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Nutrients

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https://www.readbyqxmd.com/read/29789518/olive-oil-and-soybean-oil-based-intravenous-lipid-emulsions-liver-biochemistry-and-clinical-outcomes
#1
Fabio Araujo, Tanis R Fenton, Sara Lukmanji, Maitreyi Raman
Intravenous lipid emulsions are an essential component of parenteral nutrition (PN). Omega-6 reducing strategies may improve outcomes, including reduced PN associated liver disease, however evidence to support this recommendation is insufficient. The primary objective was to compare serum alkaline phosphatase (ALP), among patients provided with either soybean oil (Intralipid) or predominantly olive oil (Clinoleic) lipid emulsions. In this quasi-experimental study, we reviewed the medical records of surgical and medical adult patients who received lipid emulsions for at least seven consecutive days...
May 23, 2018: Nutrients
https://www.readbyqxmd.com/read/29789507/acute-caffeinated-coffee-consumption-does-not-improve-time-trial-performance-in-an-800-m-run-a-randomized-double-blind-crossover-placebo-controlled-study
#2
Alexandre C Marques, Alison A Jesus, Bruna M Giglio, Ana C Marini, Patrícia C B Lobo, João F Mota, Gustavo D Pimentel
INTRODUCTION: Studies evaluating caffeinated coffee (CAF) can reveal ergogenic effects; however, studies on the effects of caffeinated coffee on running are scarce and controversial. AIM: To investigate the effects of CAF consumption compared to decaffeinated coffee (DEC) consumption on time trial performances in an 800-m run in overnight-fasting runners. METHODS: A randomly counterbalanced, double-blind, crossover, placebo-controlled study was conducted with 12 healthy adult males with experience in amateur endurance running...
May 23, 2018: Nutrients
https://www.readbyqxmd.com/read/29789472/the-impact-of-nutrition-and-health-claims-on-consumer-perceptions-and-portion-size-selection-results-from-a-nationally-representative-survey
#3
Tony Benson, Fiona Lavelle, Tamara Bucher, Amanda McCloat, Elaine Mooney, Bernadette Egan, Clare E Collins, Moira Dean
Nutrition and health claims on foods can help consumers make healthier food choices. However, claims may have a 'halo' effect, influencing consumer perceptions of foods and increasing consumption. Evidence for these effects are typically demonstrated in experiments with small samples, limiting generalisability. The current study aimed to overcome this limitation through the use of a nationally representative survey. In a cross-sectional survey of 1039 adults across the island of Ireland, respondents were presented with three different claims (nutrition claim = "Low in fat"; health claim = "With plant sterols...
May 22, 2018: Nutrients
https://www.readbyqxmd.com/read/29789466/association-of-tea-consumption-with-risk-of-alzheimer-s-disease-and-anti-beta-amyloid-effects-of-tea
#4
REVIEW
Curt Anthony Polito, Zhuo-Yu Cai, Yun-Long Shi, Xu-Min Li, Rui Yang, Meng Shi, Qing-Sheng Li, Shi-Cheng Ma, Li-Ping Xiang, Kai-Rong Wang, Jian-Hui Ye, Jian-Liang Lu, Xin-Qiang Zheng, Yue-Rong Liang
Neurodegenerative disease Alzheimer's disease (AD) is attracting growing concern because of an increasing patient population among the elderly. Tea consumption is considered a natural complementary therapy for neurodegenerative diseases. In this paper, epidemiological studies on the association between tea consumption and the reduced risk of AD are reviewed and the anti-amyloid effects of related bioactivities in tea are summarized. Future challenges regarding the role of tea in preventing AD are also discussed...
May 22, 2018: Nutrients
https://www.readbyqxmd.com/read/29789452/circulating-metabolites-associated-with-alcohol-intake-in-the-european-prospective-investigation-into-cancer-and-nutrition-cohort
#5
Eline H van Roekel, Laura Trijsburg, Nada Assi, Marion Carayol, David Achaintre, Neil Murphy, Sabina Rinaldi, Julie A Schmidt, Magdalena Stepien, Rudolf Kaaks, Tilman Kühn, Heiner Boeing, Khalid Iqbal, Domenico Palli, Vittorio Krogh, Rosario Tumino, Fulvio Ricceri, Salvatore Panico, Petra H Peeters, Bas Bueno-de-Mesquita, Eva Ardanaz, Leila Lujan-Barroso, J Ramón Quirós, José M Huerta, Elena Molina-Portillo, Miren Dorronsoro, Konstantinos K Tsilidis, Elio Riboli, Agnetha Linn Rostgaard-Hansen, Anne Tjønneland, Kim Overvad, Elisabete Weiderpass, Marie-Christine Boutron-Ruault, Gianluca Severi, Antonia Trichopoulou, Anna Karakatsani, Anastasia Kotanidou, Anders Håkansson, Johan Malm, Matty P Weijenberg, Marc J Gunter, Mazda Jenab, Mattias Johansson, Ruth C Travis, Augustin Scalbert, Pietro Ferrari
Identifying the metabolites associated with alcohol consumption may provide insights into the metabolic pathways through which alcohol may affect human health. We studied associations of alcohol consumption with circulating concentrations of 123 metabolites among 2974 healthy participants from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Alcohol consumption at recruitment was self-reported through dietary questionnaires. Metabolite concentrations were measured by tandem mass spectrometry (BIOCRATES AbsoluteIDQTM p180 kit)...
May 22, 2018: Nutrients
https://www.readbyqxmd.com/read/29786674/choline-supplementation-prevents-a-hallmark-disturbance-of-kwashiorkor-in-weanling-mice-fed-a-maize-vegetable-diet-hepatic-steatosis-of-undernutrition
#6
Thaddaeus May, Kevin C Klatt, Jacob Smith, Eumenia Castro, Mark Manary, Marie A Caudill, Farook Jahoor, Marta L Fiorotto
Hepatic steatosis is a hallmark feature of kwashiorkor malnutrition. However, the pathogenesis of hepatic steatosis in kwashiorkor is uncertain. Our objective was to develop a mouse model of childhood undernutrition in order to test the hypothesis that feeding a maize vegetable diet (MVD), like that consumed by children at risk for kwashiorkor, will cause hepatic steatosis which is prevented by supplementation with choline. A MVD was developed with locally sourced organic ingredients, and fed to weanling mice ( n = 9) for 6 or 13 days...
May 22, 2018: Nutrients
https://www.readbyqxmd.com/read/29786640/vitamin-d-in-vascular-calcification-a-double-edged-sword
#7
REVIEW
Jeffrey Wang, Jimmy J Zhou, Graham R Robertson, Vincent W Lee
Vascular calcification (VC) as a manifestation of perturbed mineral balance, is associated with aging, diabetes and kidney dysfunction, as well as poorer patient outcomes. Due to the current limited understanding of the pathophysiology of vascular calcification, the development of effective preventative and therapeutic strategies remains a significant clinical challenge. Recent evidence suggests that traditional risk factors for cardiovascular disease, such as left ventricular hypertrophy and dyslipidaemia, fail to account for clinical observations of vascular calcification...
May 22, 2018: Nutrients
https://www.readbyqxmd.com/read/29783752/pro-apoptotic-and-anti-cancer-properties-of-diosgenin-a-comprehensive-and-critical-review
#8
REVIEW
Gautam Sethi, Muthu K Shanmugam, Sudha Warrier, Myriam Merarchi, Frank Arfuso, Alan Prem Kumar, Anupam Bishayee
Novel and alternative options are being adopted to combat the initiation and progression of human cancers. One of the approaches is the use of molecules isolated from traditional medicinal herbs, edible dietary plants and seeds that play a pivotal role in the prevention/treatment of cancer, either alone or in combination with existing chemotherapeutic agents. Compounds that modulate these oncogenic processes are potential candidates for cancer therapy and may eventually make it to clinical applications. Diosgenin is a naturally occurring steroidal sapogenin and is one of the major bioactive compounds found in dietary fenugreek ( Trigonella foenum-graecum ) seeds...
May 19, 2018: Nutrients
https://www.readbyqxmd.com/read/29783749/differential-impact-of-malnutrition-on-health-outcomes-among-indigenous-and-non-indigenous-adults-admitted-to-hospital-in-regional-australia-a-prospective-cohort-study
#9
Natasha Morris, Simon Stewart, Malcolm Riley, Graeme Maguire
The burden of malnutrition in Indigenous people is a major health priority and this study's aims are to understand health outcomes among Indigenous and non-Indigenous patients. This cohort study includes 608 medical inpatients in three regional hospitals. Participants were screened for malnutrition using the Subjective Global Assessment tool. Hospital length of stay, discharge destination, 30-day and six-month hospital readmission and survival were measured. Although no significant difference was observed between Indigenous participants who were malnourished or nourished ( p = 0...
May 19, 2018: Nutrients
https://www.readbyqxmd.com/read/29783731/-lactobacillus-plantarum-strain-ln4-attenuates-diet-induced-obesity-insulin-resistance-and-changes-in-hepatic-mrna-levels-associated-with-glucose-and-lipid-metabolism
#10
Eunjung Lee, So-Ra Jung, So-Young Lee, Na-Kyoung Lee, Hyun-Dong Paik, Seong-Il Lim
The prevalence of obesity and associated metabolic disorders, including diabetes and cardiovascular disease, is rapidly becoming a severe global health problem. Recent reports have suggested that the alteration of the gut ecosystem through the consumption of probiotics and fermented foods, such as yogurt and Kimchi, can significantly impact obesity and Type 2 diabetes (T2D)-related biomarkers. In this study, we screened over 400 strains of lactic acid bacteria (LAB) that were isolated from fermented foods to identify potent anti-obesogenic and diabetic probiotics in vitro...
May 19, 2018: Nutrients
https://www.readbyqxmd.com/read/29783727/prognosis-of-dermatitis-herpetiformis-patients-with-and-without-villous-atrophy-at-diagnosis
#11
Eriika Mansikka, Kaisa Hervonen, Katri Kaukinen, Pekka Collin, Heini Huhtala, Timo Reunala, Teea Salmi
Dermatitis herpetiformis (DH) is a cutaneous manifestation of coeliac disease. At diagnosis, the majority of patients have villous atrophy in the small bowel mucosa. The objective of this study was to investigate whether the presence or absence of villous atrophy at diagnosis affects the long-term prognosis of DH. Data were gathered from the patient records of 352 DH and 248 coeliac disease patients, and follow-up data via questionnaires from 181 DH and 128 coeliac disease patients on a gluten-free diet (GFD)...
May 19, 2018: Nutrients
https://www.readbyqxmd.com/read/29783725/polyphenols-in-parkinson-s-disease-a-systematic-review-of-in-vivo-studies
#12
REVIEW
Małgorzata Kujawska, Jadwiga Jodynis-Liebert
Parkinson's disease (PD) is the second most common neurodegenerative disorder. However, therapeutic options treating only its symptoms are very disappointing. Therefore there is an ongoing search for compounds capable of tackling the multi-dimensional features of PD. Recently natural polyphenols have gained great interest as potential therapeutic agents. Herein, we have attempted to summarize results obtained in different animal models demonstrating their neuroprotective effects. The in vivo findings presented below are supported by human subject data and reports regarding the ability of polyphenols to cross the blood-brain barrier...
May 19, 2018: Nutrients
https://www.readbyqxmd.com/read/29783717/associations-of-maternal-vitamin-d-deficiency-with-pregnancy-and-neonatal-complications-in-developing-countries-a-systematic-review
#13
REVIEW
Paige van der Pligt, Jane Willcox, Ewa A Szymlek-Gay, Emily Murray, Anthony Worsley, Robin M Daly
Pregnant women in Asia, the Middle East, Africa and Latin America are at risk of vitamin D deficiency (VDD) and prevalence throughout these regions are among the highest, globally. Maternal VDD has been associated with increased risk of a number of adverse maternal and neonatal health outcomes, yet research from developing countries is limited. We assessed the associations of maternal VDD during pregnancy with adverse health outcomes by synthesizing the literature from observational studies conducted in developing countries...
May 18, 2018: Nutrients
https://www.readbyqxmd.com/read/29783689/cobalamin-and-folate-status-among-breastfed-infants-in-bhaktapur-nepal
#14
Ram K Chandyo, Manjeswori Ulak, Ingrid Kvestad, Mari Hysing, Merina Shrestha, Suman Ranjitkar, Arve Ulvik, Per Magne Ueland, Laxman Shrestha, Tor A Strand
Cobalamin and folate are crucial micronutrients during infancy and they are required for growth and cognitive development. Due to the monotonous and predominantly vegetarian-based complementary feeding and poor maternal micronutrient status, infants from low- and middle-income countries are susceptible to cobalamin deficiency. However, data on plasma cobalamin and folate and the functional markers methylmalonic acid and total homocysteine from breastfed infants in Nepal are still needed. We collected plasma samples from 316 6⁻11-month-old breastfed infants with a length-for-age of less than minus one z -score and analyzed blood for plasma folate, cobalamin, methylmalonic acid and total homocysteine concentrations...
May 18, 2018: Nutrients
https://www.readbyqxmd.com/read/29783664/erratum-estimating-free-and-added-sugar-intakes-in-new-zealand-nutrients-2017-9-1292
#15
Rachael Kibblewhite, Alice Nettleton, Rachael McLean, Jillian Haszard, Elizabeth Fleming, Devonia Kruimer, Lisa Te Morenga
The authors have requested that the following changes be made to their paper [...].
May 18, 2018: Nutrients
https://www.readbyqxmd.com/read/29783637/a-phosphatidylserine-source-of-docosahexanoic-acid-improves-neurodevelopment-and-survival-of-preterm-pigs
#16
Randal K Buddington, Victor V Chizhikov, Igor Y Iskusnykh, Helen J Sable, Jeffrey J Sable, Zade R Holloway, Tamar Blumenfeld Katzir, Marie van der Merwe, Taisiya Yakimkova, Karyl K Buddington, Yael Lifshitz, Shoshi Tessler, Ariel Gilbert
The amount, composition, and sources of nutrition support provided to preterm infants is critical for normal growth and development, and particularly for structural and functional neurodevelopment. Although omega-3 long chain polyunsaturated fatty acids (LC-PUFA), and particularly docosahexanoic acid (DHA), are considered of particular importance, results from clinical trials with preterm infants have been inconclusive because of ethical limitations and confounding variables. A translational large animal model is needed to understand the structural and functional responses to DHA...
May 18, 2018: Nutrients
https://www.readbyqxmd.com/read/29783624/growth-responses-of-preterm-pigs-fed-formulas-with-different-protein-levels-and-supplemented-with-leucine-or-%C3%AE-hydroxyl-%C3%AE-methylbutyrate
#17
Randal K Buddington, Scott C Howard, Harold W Lee, Karyl K Buddington
Growth after preterm birth is an important determinant of long-term outcomes. Yet, many preterm infants suffer ex utero growth retardation. We evaluated effects of leucine and the metabolite, β-hydroxy β-methylbutyrate (HMB) on growth of preterm pigs, a previously-validated translational model for preterm infants. After 48 h of parenteral nutrition preterm pigs were fed for 6 to 7 days isocaloric formulas with different levels of protein (50 or 100 g/L) with leucine (10 g/L, 76 mM) or HMB (at 1.1 g/L, 4 mM) added to stimulate protein synthesis or with alanine (6...
May 18, 2018: Nutrients
https://www.readbyqxmd.com/read/29772844/leucine-supplementation-does-not-attenuate-skeletal-muscle-loss-during-leg-immobilization-in-healthy-young-men
#18
Evelien M P Backx, Astrid M H Horstman, Gabriel N Marzuca-Nassr, Janneau van Kranenburg, Joey S Smeets, Cas J Fuchs, Anniek A W Janssen, Lisette C P G M de Groot, Tim Snijders, Lex B Verdijk, Luc J C van Loon
BACKGROUND: Short successive periods of physical inactivity occur throughout life and contribute considerably to the age-related loss of skeletal muscle mass. The maintenance of muscle mass during brief periods of disuse is required to prevent functional decline and maintain metabolic health. OBJECTIVE: To assess whether daily leucine supplementation during a short period of disuse can attenuate subsequent muscle loss in vivo in humans. METHODS: Thirty healthy (22 ± 1 y) young males were exposed to a 7-day unilateral knee immobilization intervention by means of a full leg cast with (LEU, n = 15) or without (CON, n = 15) daily leucine supplementation (2...
May 17, 2018: Nutrients
https://www.readbyqxmd.com/read/29772833/the-effect-of-increasing-the-protein-content-of-human-milk-fortifier-to-1-8-g-100-ml-on-growth-in-preterm-infants-a-randomised-controlled-trial
#19
Jessica Reid, Maria Makrides, Andrew J McPhee, Michael J Stark, Jacqueline Miller, Carmel T Collins
The aim of this study was to assess the effect of feeding high protein human milk fortifier (HMF) on growth in preterm infants. In this single-centre randomised trial, 60 infants born 28⁻32 weeks' gestation were randomised to receive a higher protein HMF providing 1.8 g protein ( n = 31) or standard HMF providing 1 g protein per 100 mL expressed breast milk (EBM) ( n = 29). The primary outcome was rate of weight gain. Baseline characteristics were similar between groups. There was no difference between high and standard HMF groups for weight gain (mean difference (MD) -14 g/week; 95% CI -32, 4; p = 0...
May 17, 2018: Nutrients
https://www.readbyqxmd.com/read/29772827/physicochemical-nutritional-and-organoleptic-characterization-of-a-skimmed-goat-milk-fermented-with-the-probiotic-strain-lactobacillus-plantarum-c4
#20
Miriam Moreno-Montoro, Miguel Navarro-Alarcón, Triana Bergillos-Meca, Rafael Giménez-Martínez, Silvia Sánchez-Hernández, Manuel Olalla-Herrera
The benefits of goat milk, fermented milks, and probiotics for the humans are well documented. In this study, a novel fermented goat milk was manufactured with the putative probiotic strain Lactobacillus plantarum C4 together with L. bulgaricus and Streptococcus thermophilus . Ultrafiltration was chosen as the skimmed milk concentration method because it produced the best viscosity and syneresis and a high casein content. The viability rate of all bacterial strains was >10⁷ cfu/mL, even after 5 weeks of storage or after in vitro gastrointestinal digestion, which is especially important for exertion of the probiotic strain functionalities...
May 17, 2018: Nutrients
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