Read by QxMD icon Read


Sara Massironi, Federica Branchi, Mirella Fraquelli, Alessandra Baccarin, Francesco Somalvico, Francesca Ferretti, Dario Conte, Luca Elli
The ingestion of gluten has been associated with gastrointestinal symptoms even in the absence of detectable immune responses. Little is known about the pathophysiological effects of gluten on the upper gastrointestinal tract. We aimed to assess whether the ingestion of gluten leads to an impairment of the physiological mechanisms of gastric emptying, gallbladder contraction and relaxation. A total of 17 healthy subjects underwent ultrasound evaluation of gastric emptying dynamics and gallbladder contractions at baseline and every 30 min after a standard gluten-containing and gluten-free meal (250 kcal, 70% carbohydrates)...
July 16, 2018: Nutrients
Sanne Sigh, Nanna Roos, Chhoun Chamnan, Arnaud Laillou, Sophanneary Prak, Frank T Wieringa
Cambodia continues to have a high prevalence of acute malnutrition. Low acceptability has been found for standard ready-to-use-therapeutic-food (RUTF) products. Therefore, NumTrey, a locally-produced fish-based RUTF, was developed. The objective was to evaluate the effectiveness of NumTrey compared to an imported milk-based RUTF for weight gain among children aged 6⁻59 months in the home-treatment for acute malnutrition. Effectiveness was tested in a single-blinded randomized controlled trial with weight gain as the primary outcome...
July 16, 2018: Nutrients
Eleni Asteriou, Athanasios Gkoutzourelas, Athanasios Mavropoulos, Christina Katsiari, Lazaros I Sakkas, Dimitrios P Bogdanos
We propose curcumin as a preventive measure to avoid/manage periodontitis (PD), and as a natural immunosuppressant for rheumatoid arthritis (RA). PD, mainly caused by Porphyromonas gingivalis forming biofilm and leading to tooth decay, is a major public health issue and a risk factor for the development of RA in humans. P. gingivalis is able to trigger experimental autoimmune arthritis in animal models and in humans can induce citrullinated peptides, which not only are a source of anti-citrullinated antibodies (ACPAs), but also participate in autoreactive responses and disease development...
July 16, 2018: Nutrients
Haichao Wang, Sisi Li, Shenglin Fang, Xiaojing Yang, Jie Feng
To investigate the role of betaine in the intestinal functions of high-salt stressed rats, 32 four-week-old male Sprague⁻Dawley rats weighing 128.0 (SD 5.06) g were randomly allotted to four groups. The control group was fed with standard chow diet (0.4% NaCl), while the treatment groups were fed a high-salt diet (4.0% NaCl) supplemented with betaine at 0.0%, 0.5%, and 1.0%, respectively. The experiment lasted 28 days. The results showed that rats in the high-salt stressed groups had a significant increase in both water intake and kidney index ( p < 0...
July 16, 2018: Nutrients
Robert Hamlin, Lisa McNeill
Front-of-pack (FoP) nutrition labels are a widely deployed tool in public good marketing. This article reports on a field experimental test of the impact of one of these systems, the Australasian Health Star Rating system (HSR), on consumer choice in the breakfast cereals category in New Zealand. This study forms part of a time-series replication stream of research on this topic. The research applied a 2 × 2 factorial design with multiple replications to retail food consumers exiting from supermarkets in New Zealand...
July 16, 2018: Nutrients
Blanka Klímová, Martin Vališ
Current demographic trends indicate that the population is aging. The aging process is inevitably connected with cognitive decline, which manifests itself in worsening working memory, processing speed, and attention. Therefore, apart from pharmacological therapies, non-pharmacological approaches which can influence cognitive performance (such as physical activities or healthy diet), are being investigated. The purpose of this study is to explore the types of nutritional interventions and their benefits in the prevention and delay of cognitive delay in healthy older individuals...
July 15, 2018: Nutrients
Mensiena B G Kiewiet, Marijke M Faas, Paul de Vos
Immunomodulatory protein hydrolysate consumption may delay or prevent western immune-related diseases. In order to purposively develop protein hydrolysates with an optimal and reproducible immunomodulatory effect, knowledge is needed on which components in protein hydrolysates are responsible for the immune effects. Important advances have been made on this aspect. Also, knowledge on mechanisms underlying the immune modulating effects is indispensable. In this review, we discuss the most promising application possibilities for immunomodulatory protein hydrolysates...
July 14, 2018: Nutrients
Jesús Gilberto Arámburo-Galvez, Norberto Sotelo-Cruz, Lilian Karem Flores-Mendoza, Martina Hilda Gracia-Valenzuela, Francisco Iván Rodolfo Chiquete-Elizalde, Jesús Guadalupe Espinoza-Alderete, Humberto Trejo-Martínez, Vicente Adrián Canizalez-Román, Noé Ontiveros, Francisco Cabrera-Chávez
Most food allergy cases are associated with a limited group of allergens. This could be attributed to an increased ability of some foods to sensitize and trigger allergic reactions. However, there are no validated animal models to evaluate the sensitizing or allergenic potentials of proteins. Our aim was to evaluate three protocols of adjuvant-free intraperitoneal sensitization that differ in the time points for sample collection (days 14, 28 and 35 from beginning of the sensitization) and also in the number of immunizations (2, 5 and 3, respectively)...
July 14, 2018: Nutrients
Yuko Ikemoto, Keiji Kuroda, Koji Nakagawa, Asako Ochiai, Rie Ozaki, Keisuke Murakami, Makoto Jinushi, Akemi Matsumoto, Rikikazu Sugiyama, Satoru Takeda
Vitamin D (VD) deficiency is associated with reproductive failure. However, the relationship between VD and maternal immunity remains unclear. We investigated the clinical efficacy of VD in maternal T-helper (Th) cytokines in 276 infertile women and examined for Th1 and Th2 cells based on the deficient, insufficient, and sufficient serum 25-hydroxyvitamin D3 (25[OH]VD) levels (<12, 12⁻30, and >30 ng/mL, respectively). Most infertile women had a low-level of VD (87.3%). Immunological tests of pre-/post-VD supplementation were performed in patients who were deficient and insufficient in VD...
July 13, 2018: Nutrients
Youn-Hwan Hwang, Hyunil Ha, Rajeong Kim, Chang-Won Cho, Young-Ran Song, Hee-Do Hong, Taesoo Kim
Persimmon ( Diospyros kaki L.f.) leaves have traditionally been used as a phytomedicine, in health beverages to treat cardiovascular and respiratory disease and to promote maternal health in East Asia. In particular, polysaccharides from persimmon are known to have anti-coagulant, anti-oxidant, and immune-stimulatory activities. However, their beneficial effects against osteoporosis have not been reported. In the present study, we investigated the anti-osteoporotic effects of polysaccharides from persimmon leaves (PLE0) using an in vivo model of ovariectomy (OVX)-induced bone loss and an in vitro system of receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast differentiation...
July 13, 2018: Nutrients
Sairah L Chen, Cecilie Dahl, Haakon E Meyer, Ahmed A Madar
High dietary salt intake is associated with increased blood pressure (BP) and cardiovascular disease (CVD) risk. The migration of Somalis from East Africa to Norway may have altered their dietary habits, making them vulnerable to adverse health outcomes. Since little is known about the lifestyle and health status of this population, the purpose of our study was to estimate salt intake in Somali adults in Oslo, Norway. In this cross-sectional study, we included 161 Somali adults (76 men, 86 women) from the Sagene borough in Oslo, Norway...
July 13, 2018: Nutrients
Masahiro Kita, Kuniaki Obara, Sumio Kondo, Satoshi Umeda, Yasuhisa Ano
Background: Previous epidemiological and clinical studies have shown that dairy products have beneficial effects on cognitive decline and dementia. Enzymatic digestion of whey protein produces a whey peptide rich in tryptophan-tyrosine-related peptides which improve cognitive performance in mice. We evaluated the effects of whey peptides on cognitive functions in healthy adults in a randomized, double-blind, placebo-controlled design. Methods: 101 healthy adults (45 to 64 years), with a self-awareness of cognitive decline received either whey peptide or placebo supplements for 12 weeks...
July 13, 2018: Nutrients
Antonella Agodi, Andrea Maugeri, Sarka Kunzova, Ondrej Sochor, Hana Bauerova, Nikola Kiacova, Martina Barchitta, Manlio Vinciguerra
Although metabolic syndrome (MetS) could be handled by lifestyle interventions, its relationship with dietary patterns remains unclear in populations from Central Europe. Using data from the Kardiovize Brno cohort, the present study aims to identify the main dietary patterns and to evaluate their association with MetS risk in a random urban sample from Brno, Czech Republic. In a cross-sectional study of 1934 subjects aged 25⁻65 years (44.3% male), dietary patterns were derived by food frequency questionnaire (FFQ) administration and principal component analysis...
July 13, 2018: Nutrients
Haifa Maalmi, Viola Walter, Lina Jansen, Daniel Boakye, Ben Schöttker, Michael Hoffmeister, Hermann Brenner
Previous meta-analyses have shown an improved survival with higher blood 25-hydroxyvitamin D (25(OH)D) concentrations in patients with colorectal cancer (CRC). However, a number of much larger studies have been published since then. We provide an updated meta-analysis to synthesize current evidence. PubMed and Web of Science databases were systematically searched for eligible studies. The dose-response relationships and pooled hazard ratios for overall and CRC-specific survival comparing the highest versus the lowest categories of blood 25(OH)D concentrations were assessed...
July 13, 2018: Nutrients
Dominika Guzek, Dominika Głąbska, Blanka Mellová, Katarzyna Zadka, Katarzyna Żywczyk, Krystyna Gutkowska
Among the factors that may influence fruit and vegetable intake, there is a food neophobia level, but the other elements, including physical activity and place of residence, must also be taken into account as interfering ones. The aim of the study was to analyze the association between food neophobia level and the intake of fruits and vegetables in a nationwide case-control study of Polish adolescents (12⁻13 years), including the influence of gender, the physical activity program participation and the place of residence...
July 13, 2018: Nutrients
Renée Wilson, Jinny Willis, Richard B Gearry, Alan Hughes, Blair Lawley, Paula Skidmore, Chris Frampton, Elizabeth Fleming, Angie Anderson, Lizzie Jones, Gerald W Tannock, Anitra C Carr
Kiwifruit are a nutrient dense food and an excellent source of vitamin C. Supplementation of the diet with kiwifruit enhances plasma vitamin C status and epidemiological studies have shown an association between vitamin C status and reduced insulin resistance and improved blood glucose control. In vitro experiments suggest that eating kiwifruit might induce changes to microbiota composition and function; however, human studies to confirm these findings are lacking. The aim of this study was to investigate the effect of consuming two SunGold kiwifruit per day over 12 weeks on vitamin C status, clinical and anthropometric measures and faecal microbiota composition in people with prediabetes...
July 12, 2018: Nutrients
Shih-Yi Huang, Li-Han Chen, Ming-Fu Wang, Chih-Chieh Hsu, Ching-Hung Chan, Jia-Xian Li, Hui-Yu Huang
Probiotic supplements are potential therapeutic agents for age-related disorders due to their antioxidant and anti-inflammatory properties. However, the effect of probiotics on age-related brain dysfunction remains unclear. To investigate the effects of Lactobacillus paracasei PS23 (LPPS23) on the progression of age-related cognitive decline, male and female senescence-accelerated mouse prone 8 (SAMP8) mice were divided into two groups ( n = 6 each): the control and PS23 groups. From the age of 16 weeks, these groups were given saline and LPPS23, respectively, because SAMP8 mice start aging rapidly after four months of age...
July 12, 2018: Nutrients
Chihiro Kojima, Nobukazu Kasai, Chika Kondo, Kumiko Ebi, Kazushige Goto
PURPOSE: The purpose of the present study was to investigate the effect of whole-body cryotherapy (WBC) treatment after exercise on appetite regulation and energy intake. METHODS: Twelve male athletes participated in two trials on different days. In both trials, participants performed high-intensity intermittent exercise. After 10 min following the completion of the exercise, they were exposed to a 3-min WBC treatment (-140 °C, WBC trial) or underwent a rest period (CON trial)...
July 12, 2018: Nutrients
Iva Hoffmanová, Daniel Sánchez, Ludmila Tučková, Helena Tlaskalová-Hogenová
Immunologically mediated liver diseases belong to the common extraintestinal manifestations of celiac disease. We have reviewed the current literature that addresses the association between celiac disease and liver disorders. We searched relevant articles on MEDLINE/PubMed up to 15 June 2018. The objective of the article is to provide a comprehensive and up-to-date review on the latest hypotheses explaining the pathogenetic relationship between celiac disease and liver injury. Besides the involvement of gut⁻liver axis, tissue transglutaminase antibodies, and impairment of intestinal barrier, we integrate the latest achievements made in elucidation of the role of gut microbiota in celiac disease and liver disorders, that has not yet been sufficiently discussed in the literature in this context...
July 12, 2018: Nutrients
Nathalie Kliemann, Mariana V S Kraemer, Tailane Scapin, Vanessa M Rodrigues, Ana C Fernandes, Greyce L Bernardo, Paula L Uggioni, Rossana P C Proença
The presentation of nutrition information on a serving size basis is a strategy that has been adopted by several countries to promote healthy eating. Variation in serving size, however, can alter the nutritional values reported on food labels and compromise the food choices made by the population. This narrative review aimed to discuss (1) current nutrition labelling legislation regarding serving size and (2) the implications of declared serving size for nutrition information available on packaged foods. Most countries with mandatory food labelling require that serving size be presented on food labels, but variation in this information is generally allowed...
July 12, 2018: Nutrients
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"