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Journal of Global Infectious Diseases

Maheshkumar Lakhe, Saiprasad Vilas Patil, Krishnaprasad Korukonda, Amit Bhargava
No abstract text is available yet for this article.
July 2016: Journal of Global Infectious Diseases
Saraschandra Vallabhajosyula, Muralidhar D Varma, Saarwaani Vallabhajosyula, Shashaank Vallabhajosyula
No abstract text is available yet for this article.
July 2016: Journal of Global Infectious Diseases
Tamara M Johnson, Chandrika Chitturi, Michael Lange, Jin S Suh, Jihad Slim
Streptococcus pneumoniae vertebral infections have rarely been reported. Herein, we report a case of pneumococcal vertebral osteomyelitis with paraspinal and epidural abscesses as well as concomitant bacteremia following epidural injection. This will be the second case in the literature reporting pneumococcal vertebral osteomyelitis related to epidural manipulation.
July 2016: Journal of Global Infectious Diseases
Sriram Pothapregada, Banupriya Kamalakannan, Mahalaskhmy Thulasingham, Srinivasan Sampath
OBJECTIVE: To study the clinical profile and outcome of dengue fever in children at a tertiary care hospital in Puducherry. MATERIALS AND METHODS: All children (0-12 years of age) diagnosed and confirmed as dengue fever from August 2012 to January 2015 were reviewed retrospectively from hospital case records as per the revised World Health Organization guidelines for dengue fever. The diagnosis was confirmed by NS1 antigen-based ELISA test or dengue serology for IgM and IgG antibodies, and the data were analyzed using SPSS 16...
July 2016: Journal of Global Infectious Diseases
Eleonora Cella, Alessandra Lo Presti, Marta Giovanetti, Carla Veo, Alessia Lai, Giordano Dicuonzo, Silvia Angeletti, Marco Ciotti, Gianguglielmo Zehender, Massimo Ciccozzi
CONTEXT: Human immunodeficiency virus type 2 (HIV-2) infections are mainly restricted to West Africa; however, in the recent years, the prevalence of HIV-2 is a growing concern in some European countries and the Southwestern region of India. Despite the presence of different HIV-2 groups, only A and B Groups have established human-to-human transmission chains. AIMS: This work aimed to evaluate the phylogeographic inference of HIV-2 Group B worldwide to estimate their data of origin and the population dynamics...
July 2016: Journal of Global Infectious Diseases
Pradyot Prakash, Shashikant C U Patne, Ashish Kumar Singh, Mohan Kumar, Mukti Nath Mishra, Anil Kumar Gulati
AIMS: To devise nested multiplex polymerase chain reaction (NMPCR) protocol for detection of mucosal human papilloma viruses (HPVs) and typing of HPV-16 and -18 in formalin-fixed, paraffin-embedded (FFPE) tissues of carcinoma cervix (CaCx). SETTINGS AND DESIGN: Cross-sectional observational study. MATERIALS AND METHODS: NMPCR was done for simultaneous detection of HPV, targeting 134 bp L1 capsid gene employing GP+/mGP+ primers and typing of genotypes-16 and -18, targeting E6/E7 gene from 34 FFPE tissue blocks of CaCx and cervical intraepithelial neoplasia (CIN)...
July 2016: Journal of Global Infectious Diseases
Nitin Gupta, Rama Chaudhry, Chandan Kumar Thakur
BACKGROUND: The most common method employed for diagnosis of scrub typhus is serology. It is widely known that demonstration of ≥4-fold rise in titers of antibody in paired sera is required for diagnosis. However, for guidance of initial treatment, there is a need for rapid diagnosis at the time of admission. Therefore, there is a need for standardized region specific cutoff titers at the time of admission. MATERIALS AND METHODS: A total of 258 patients of all age groups with clinically suspected scrub typhus over a period of 24 months (October 2013-October 2015) were enrolled...
July 2016: Journal of Global Infectious Diseases
Lakshay Chanana, Karishma Atre, Sagar Galwankar, Dhanashree Kelkar
No abstract text is available yet for this article.
July 2016: Journal of Global Infectious Diseases
Theocharis Koufakis, Ioannis Gabranis
No abstract text is available yet for this article.
April 2016: Journal of Global Infectious Diseases
Jeevan Malaiyan, Padmasani Venkat Ramanan, Dinesh Subramaniam, Thangam Menon
BACKGROUND: The mumps virus is frequently the causative agent of parotitis. There has been no study on serum cytokine levels of acute mumps parotitis except for a few which document cytokine levels in cerebrospinal fluid of mumps meningitis. It is with this notion, our study aimed to find Th1/Th2 cytokine levels from patients with acute mumps parotitis. MATERIALS AND METHODS: Concentrations of mumps-specific IgM, mumps, measles, rubella-specific IgG antibody, and Th1/Th2 cytokines, namely interferon-γ (IFN-γ), interleukin-2 (IL-2), IL-4, and IL-10 were measured simultaneously in serum from 74 patients (42 pediatric and 32 adult cases), 40 healthy subjects (20 pediatric and 20 adults) and in the supernatant of peripheral blood mononuclear cells stimulated with mumps virus genotype C which served as the positive control...
April 2016: Journal of Global Infectious Diseases
Suman Mitra, Anindya Mukherjee, Dibbendhu Khanra, Ananya Bhowmik, Krishnendu Roy, Arunansu Talukdar
CONTEXT: Parasitic opportunistic infections (POIs) frequently occur in HIV/AIDS patients and affect the quality of life. AIMS: This study assessing the standard organisms in the stool of HIV-positive patients, their comparison with HIV-negative controls, their relation with various factors, is the first of its kind in the eastern part of India. SETTINGS AND DESIGN: hospital-based case-control study. MATERIALS AND METHODS: A total of 194 antiretroviral therapy naïve HIV-positive patients (18-60 years) were taken as cases and 98 age- and sex-matched HIV-negative family members as controls...
April 2016: Journal of Global Infectious Diseases
Afiono Agung Prasetyo, Ruben Dharmawan, Irvan Raharjo, Hudiyono
CONTEXT: Data regarding the distribution of Human Leukocyte Antigen (HLA)-E alleles and their association with blood-borne pathogen infections/co-infections are limited for many populations, including Indonesia. AIMS: The aim of this study was to analyze the association between HLA-E allelic variants and infection with blood-borne pathogens such as hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis D virus (HDV), torque teno virus (TTV), GB virus C (GBV-C), and Toxoplasma gondii (T...
April 2016: Journal of Global Infectious Diseases
Toms John Peedikayil Neetu, Sevanan Murugan
BACKGROUND: Globally, methicillin resistant Staphylococcus aureus (MRSA) is one of the most common pathogens that causes hospital- and community-acquired infections. The use of molecular typing methods is essential for determining the origin of the isolates, their clonal relations, and also epidemiological investigations. OBJECTIVE: The purpose of this study was to determine the prevalence of antibiotic-resistant MRSA investigate the accessory gene regulator (agr) and staphylococcal cassette chromosome mec (SCCmec) types and perform multilocus sequence typing (MLST)...
April 2016: Journal of Global Infectious Diseases
Kaustubh Suresh Chaudhari, Sahil Prashant Uttarwar, Nikhil Narayan Tambe, Rohan S Sharma, Anant Arunrao Takalkar
INTRODUCTION: There is no comprehensive data or studies relating to clinical presentation and prognosis of cerebral malaria (CM) in the tribal settlements of Assam. High rates of transmission and deaths from complicated malaria guided us to conduct a prospective observational cohort study to evaluate the factors associated with poor outcome and prognosis in patients of CM. MATERIALS AND METHODS: We admitted 112 patients to the Bandarpara and Damodarpur Tribal Health Centers (THCs) between 2011 and 2013 with a strict diagnosis of CM...
April 2016: Journal of Global Infectious Diseases
Vivek Chauhan, Sunil Kumar Raina, Suman Thakur
No abstract text is available yet for this article.
April 2016: Journal of Global Infectious Diseases
Harsh C Sutariya, Tejal N Panchal, Vaidehi K Pandya, Kajal N Patel
No abstract text is available yet for this article.
January 2016: Journal of Global Infectious Diseases
Tanmay S Panchabhai, Chirag Choudhary, Carlos Isada, Erik Folch, Atul C Mehta
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by polyomavirus John Cunningham (JC) virus. We report the case of a 60-year-old woman who presented 16 months after right single lung transplant with worsening memory, behavioral problems, emotional lability, and progressive left upper extremity weakness. Magnetic resonance imaging revealed white matter changes suggestive of PML. JC virus infection was confirmed with polymerase chain reaction (PCR) from both the bronchoalveolar lavage (BAL) fluid and cerebrospinal fluid...
January 2016: Journal of Global Infectious Diseases
Yamuna Devi Bakthavatchalam, Shalini Anandan, Balaji Veeraraghavan
Carbapenemase producing Gram-negative pathogen is of great concern for physician. The challenging aspects are treatment option and infection control. Monitoring of respective carbapenemase resistance mechanism is necessary to prevent the outbreaks. Currently, the rapid emergence of oxacillinase (OXA-48) like is alarming. Increasing frequency of OXA-48 is seen than the classical carbapenemase (KPC, NDM, IMP, and VIM) across the world. The bla OXA-48 gene is commonly identified in Escherichia coli and Klebsiella pneumoniae...
January 2016: Journal of Global Infectious Diseases
Ravdeep Kaur, Kavita Kachroo, Jitendar Kumar Sharma, Satyanarayana Murthy Vatturi, Amit Dang
BACKGROUND: World Health Organization (WHO) recommends the use of Xpert MTB/RIF assay for rapid diagnosis of tuberculosis (TB) and detection of rifampicin resistance. This systematic review was done to know about the diagnostic accuracy and cost-effectiveness of the Xpert MTB/RIF assay. METHODS: A systematic literature search was conducted in following databases: Cochrane Central Register of Controlled Trials and Cochrane Database of Systematic Reviews, MEDLINE, PUBMED, Scopus, Science Direct and Google Scholar for relevant studies for studies published between 2010 and December 2014...
January 2016: Journal of Global Infectious Diseases
Richa Gupta, Abida Malik, Meher Rizvi, S Moied Ahmed
BACKGROUND: Multidrug-resistant (MDR) Pseudomonas spp. have been reported to be the important cause of ICU infections. The appearance of ESBL, AmpC and MBL genes and their spread among bacterial pathogens is a matter of great concern. Biofilm production also attributes to antimicrobial resistance due to close cell to cell contact that permits bacteria to more effectively transfer plasmids to one another. This study aimed at determining the incidence of ESBL, AmpC, MBL and biofilm producing Pseudomonas spp...
January 2016: Journal of Global Infectious Diseases
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