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Journal of Cancer Epidemiology

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https://www.readbyqxmd.com/read/28894467/racial-and-socioeconomic-disparities-are-more-pronounced-in-inflammatory-breast-cancer-than-other-breast-cancers
#1
Ryan A Denu, John M Hampton, Adam Currey, Roger T Anderson, Rosemary D Cress, Steven T Fleming, Joseph Lipscomb, Xiao-Cheng Wu, J Frank Wilson, Amy Trentham-Dietz
Inflammatory breast cancer (IBC) is a rare yet aggressive form of breast cancer. We examined differences in patient demographics and outcomes in IBC compared to locally advanced breast cancer (LABC) and all other breast cancer patients from the Breast and Prostate Cancer Data Quality and Patterns of Care Study (POC-BP), containing information from cancer registries in seven states. Out of 7,624 cases of invasive carcinoma, IBC and LABC accounted for 2.2% (N = 170) and 4.9% (N = 375), respectively. IBC patients were more likely to have a higher number (P = 0...
2017: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/28744312/prevalence-of-egfr-mutations-in-lung-cancer-in-uruguayan-population
#2
Nora Berois, Diego Touya, Luis Ubillos, Bernardo Bertoni, Eduardo Osinaga, Mario Varangot
BACKGROUND: Incorporation of molecular analysis of the epidermal growth factor receptor (EGFR) gene into routine clinical practice represents a milestone for personalized therapy of the non-small-cell lung cancer (NSCLC). However, the genetic testing of EGFR mutations has not yet become a routine clinical practice in developing countries. In view of different prevalence of such mutations among different ethnicities and geographic regions, as well as the limited existing data from Latin America, our aim was to study the frequency of major types of activating mutations of the EGFR gene in NSCLC patients from Uruguay...
2017: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/28702054/the-role-of-neighborhood-characteristics-in-late-stage-melanoma-diagnosis-among-hispanic-men-in-california-texas-and-florida-1996-2012
#3
Valerie M Harvey, Clinton W Enos, Jarvis T Chen, Hadiza Galadima, Karl Eschbach
BACKGROUND: Hispanics diagnosed with cutaneous melanoma are more likely to present at advanced stages but the reasons for this are unknown. We identify census tracts at high risk for late stage melanoma diagnosis (LSMD) and examine the contextual predictors of LSMD in California, Texas, and Florida. METHODS: We conducted a cross-sectional study using geocoded state cancer registry data. Using hierarchical multilevel logistic regression models we estimated ORs and 95% confidence intervals for the impact of socioeconomic, Hispanic ethnic concentration, index of dissimilarity, and health resource availability measures on LSMD...
2017: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/28487737/insurance-status-is-related-to-receipt-of-therapy-and-survival-in-patients-with-early-stage-pancreatic-exocrine-carcinoma
#4
Emily Boevers, Bradley D McDowell, Sarah L Mott, Anna M Button, Charles F Lynch
Objectives. The study objective was to determine how insurance status relates to treatment receipt and overall survival for patients with early-stage pancreatic exocrine carcinoma. Methods. SEER data were evaluated for 17,234 patients diagnosed with Stage I/II pancreatic exocrine carcinoma. Multivariate regression models controlled for personal characteristics to determine whether insurance status was independently associated with overall survival and receipt of radiation/surgery. Results. Odds of receiving radiation were 1...
2017: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/28484492/relationships-between-global-dna-methylation-in-circulating-white-blood-cells-and-breast-cancer-risk-factors
#5
REVIEW
Nayha Chopra-Tandon, Haotian Wu, Kathleen F Arcaro, Susan R Sturgeon
It is not yet clear whether white blood cell DNA global methylation is associated with breast cancer risk. In this review we examine the relationships between multiple breast cancer risk factors and three markers of global DNA methylation: LINE-1, 5-mdC, and Alu. A literature search was conducted using Pubmed up to April 1, 2016, using combinations of relevant outcomes such as "WBC methylation," "blood methylation," "blood LINE-1 methylation," and a comprehensive list of known and suspected breast cancer risk factors...
2017: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/28321255/cancer-prevention-in-low-and-middle-income-countries
#6
EDITORIAL
Subhojit Dey, Preet K Dhillon, Preetha Rajaraman
No abstract text is available yet for this article.
2017: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/28239395/patterns-of-sociodemographic-and-clinicopathologic-characteristics-of-stages-ii-and-iii-colorectal-cancer-patients-by-age-examining-potential-mechanisms-of-young-onset-disease
#7
Caitlin C Murphy, Hanna K Sanoff, Karyn B Stitzenberg, John A Baron, Jennifer L Lund, Robert S Sandler
Background and Aims. As a first step toward understanding the increasing incidence of colorectal cancer (CRC) in younger (age < 50) populations, we examined demographic, clinicopathologic, and socioeconomic characteristics and treatment receipt in a population-based sample of patients newly diagnosed with stages II and III CRC. Methods. Patients were sampled from the National Cancer Institute's Patterns of Care studies in 1990/91, 1995, 2000, 2005, and 2010 (n = 6, 862). Tumor characteristics and treatment data were obtained through medical record review and physician verification...
2017: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/28133481/a-case-control-study-of-risk-factors-for-salivary-gland-cancer-in-canada
#8
Sai Yi Pan, Margaret de Groh, Howard Morrison
Aim. To assess the effect of various lifestyle risk factors on the risk of salivary gland cancer in Canada using data from a population-based case-control study. Methods. Data from a population-based case-control study of 132 incident cases of salivary gland cancer and 3076 population controls were collected through self-administered questionnaire and analysed using unconditional logistic regression. Results. Four or more servings/week of processed meat product was associated with an adjusted odds ratio (OR) and corresponding 95% confidence interval (CI) of 1...
2017: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/28070189/role-of-private-enterprise-in-cancer-control-in-low-to-middle-income-countries
#9
REVIEW
Chukwumere E Nwogu, Martin Mahoney, Ifeoma Okoye, Kenneth Ejiogu, Saby George, Grace Dy, Mutiu Jimoh, Omolola Salako, Oge Ilegbune, Bindiya Chugani, Emmanuel Ezeome, Abiodun O Popoola, Arthur M Michalek
Background. About 65% of cancer deaths globally occur in low to middle income countries (LMICs) where prioritization and allocation of resources to cancer care are often quite poor. In the absence of governmental focus on this problem, public-private partnerships may be an avenue to provide effective cancer control. Methods. This manuscript highlights the establishment of a nongovernmental organization (NGO) to stimulate the development of partnerships between oncology professionals, private enterprise, and academic institutions, both locally and internationally...
2016: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/28018431/genetic-and-clinical-features-of-medullary-thyroid-carcinoma-the-experience-of-a-single-center-in-costa-rica
#10
Javier Calvo, Gabriel Torrealba, Adriana Sáenz, Carlos Santamaría, Estela Morera, Silvia Alvarado, Yolanda Roa, Michelle González
Background. Activating mutations in the RET gene leads to medullary thyroid carcinoma (MTC). Guidelines encourage performing RET analysis in subjects with hereditary and sporadic disease. Materials and Methods. Design. Observational, case series report study. Patients. Subjects diagnosed with MTC, with a thyroidectomy performed in a single center in Costa Rica between the years 2006 and 2015. Diagnosis and Follow-Up. Pre- and postoperative calcitonin, RET mutation, and neck ultrasound and tomography were obtained...
2016: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/27965709/pattern-and-distribution-of-colorectal-cancer-in-tanzania-a-retrospective-chart-audit-at-two-national-hospitals
#11
Leonard K Katalambula, Julius Edward Ntwenya, Twalib Ngoma, Joram Buza, Emmanuel Mpolya, Abdallah H Mtumwa, Pammla Petrucka
Background. Colorectal cancer (CRC) is a growing public health concern with increasing rates in countries with previously known low incidence. This study determined pattern and distribution of CRC in Tanzania and identified hot spots in case distribution. Methods. A retrospective chart audit reviewed hospital registers and patient files from two national institutions. Descriptive statistics, Chi square (χ(2)) tests, and regression analyses were employed and augmented by data visualization to display risk variable differences...
2016: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/27882054/risk-of-cancer-among-commercially-insured-hiv-infected-adults-on-antiretroviral-therapy
#12
Jeannette Y Lee, Ishwori Dhakal, Corey Casper, Ariela Noy, Joel M Palefsky, Missak Haigentz, Susan E Krown, Richard F Ambinder, Ronald T Mitsuyasu
The objective of this study was to explore the cancer incidence rates among HIV-infected persons with commercial insurance who were on antiretroviral therapy and compare them with those rates in the general population. Paid health insurance claims for 63,221 individuals 18 years or older, with at least one claim with a diagnostic code for HIV and at least one filled prescription for an antiretroviral medication between January 1, 2006, and September 30, 2012, were obtained from the LifeLink® Health Plan Claims Database...
2016: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/27721828/screening-of-oral-potentially-malignant-disorders-using-exfoliative-cytology-a-diagnostic-modality
#13
Arpita Kabiraj, Tanya Khaitan, Debarati Bhowmick, Uday Ginjupally, Aritri Bir, Kushal Chatterjee
Objective. Oral exfoliative cytology (OEC) has been implemented in the diagnosis of pathologic lesions for ages. The present study was undertaken to evaluate the cytomorphological features of some of the commonest potentially malignant disorders (leukoplakia, lichen planus, and oral submucous fibrosis) through a simple procedure and illustrate its importance in mass screening. Materials and Method. A total of 160 subjects with 25-50 years of age were included in the study. Among them, 40 were clinically diagnosed with oral leukoplakia, 40 were diagnosed with oral lichen planus, 40 were diagnosed with oral submucous fibrosis, and 40 were in the control group...
2016: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/27672394/breast-cancer-prevalence-and-mortality-among-hispanic-subgroups-in-the-united-states-2009-2013
#14
Bijou R Hunt
Background. This paper presents data on breast cancer prevalence and mortality among US Hispanics and Hispanic subgroups, including Cuban, Mexican, Puerto Rican, Central American, and South American. Methods. Five-year average annual female breast cancer prevalence and mortality rates for 2009-2013 were examined using data from the National Health Interview Survey (prevalence) and the National Center for Health Statistics and the American Community Survey (mortality rates). Results. Overall breast cancer prevalence among US Hispanic women was 1...
2016: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/27239197/coffee-consumption-and-the-incidence-of-colorectal-cancer-in-women
#15
Erik J Groessl, Matthew A Allison, Joseph C Larson, Samuel B Ho, Linda G Snetslaar, Dorothy S Lane, Katie M Tharp, Marcia L Stefanick
Background. Higher coffee consumption has been associated with decreased incidence of colorectal cancer. Our objective was to examine the relationship of coffee intake to colorectal cancer incidence in a large observational cohort of postmenopausal US women. Methods. Data were collected for the Women's Health Initiative Observational Study providing a follow-up period of 12.9 years. The mean age of our sample (N = 83,778 women) was 63.5 years. Daily coffee intake was grouped into 3 categories: None, moderate (>0-<4 cups), and high (4+ cups)...
2016: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/27118972/promoter-methylation-and-mrna-expression-of-response-gene-to-complement-32-in-breast-carcinoma
#16
Ebrahim Eskandari-Nasab, Mohammad Hashemi, Firoozeh Rafighdoost
Background. Response gene to complement 32 (RGC32), induced by activation of complements, has been characterized as a cell cycle regulator; however, its role in carcinogenesis is still controversial. In the present study we compared RGC32 promoter methylation patterns and mRNA expression in breast cancerous tissues and adjacent normal tissues. Materials and Methods. Sixty-three breast cancer tissues and 63 adjacent nonneoplastic tissues were included in our study. Design. Nested methylation-specific polymerase chain reaction (Nested-MSP) and quantitative PCR (qPCR) were used to determine RGC32 promoter methylation status and its mRNA expression levels, respectively...
2016: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/27034669/the-influences-of-health-insurance-and-access-to-information-on-prostate-cancer-screening-among-men-in-dominican-republic
#17
Joseph Kangmennaang, Isaac Luginaah
Objectives. Although research demonstrates the public health burden of prostate cancer among men in the Caribbean, relatively little is known about the factors that underlie the low levels of testing for the disease among this population. Study Design. A cross-sectional study of prostate cancer testing behaviours among men aged 40-60 years in Dominican Republic using the Demographic and Health Survey (2013). Methods. We use hierarchical binary logit regression models and average treatment effects combined with propensity score matching to explore the determinants of prostate screening as well as the average effect of health insurance coverage on screening...
2016: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/27034668/prostate-cancer-screening-in-jamaica-results-of-the-largest-national-screening-clinic
#18
Belinda F Morrison, William Aiken, Richard Mayhew, Yulit Gordon, Marvin Reid
Prostate cancer is highly prevalent in Jamaica and is the leading cause of cancer-related deaths. Our aim was to evaluate the patterns of screening in the largest organized screening clinic in Jamaica at the Jamaica Cancer Society. A retrospective analysis of all men presenting for screening at the Jamaica Cancer Society from 1995 to 2005 was done. All patients had digital rectal examinations (DRE) and prostate specific antigen (PSA) tests done. Results of prostate biopsies were noted. 1117 men of mean age 59...
2016: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/26880917/what-prevents-men-aged-40-64-years-from-prostate-cancer-screening-in-namibia
#19
Joseph Kangmennaang, Paul Mkandawire, Isaac Luginaah
Objectives. Although a growing body of evidence demonstrates the public health burden of prostate cancer in SSA, relatively little is known about the underlying factors surrounding the low levels of testing for the disease in the context of this region. Using Namibia Demographic Health Survey dataset (NDHS, 2013), we examined the factors that influence men's decision to screen for prostate cancer in Namibia. Methods. We use complementary log-log regression models to explore the determinants of screening for prostate cancer...
2016: Journal of Cancer Epidemiology
https://www.readbyqxmd.com/read/26880916/determinants-of-cervical-cancer-screening-uptake-among-women-in-ilorin-north-central-nigeria-a-community-based-study
#20
Ajibola Idowu, Samuel Anu Olowookere, Aderonke Tolulope Fagbemi, Olumuyiwa Ayotunde Ogunlaja
Introduction. Cancer of the cervix is the leading cause of cancer deaths among women in developing countries. Screening is one of the most cost effective control strategies for the disease. This study assessed the determinants of cervical cancer screening uptake among Nigerian women. Methodology. This cross-sectional study was conducted using multistage sampling technique among 338 participants in Ilorin, North Central Nigeria. A pretested questionnaire was used for data collection and data analysis was done using SPSS version 21...
2016: Journal of Cancer Epidemiology
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