journal
MENU ▼
Read by QxMD icon Read
search

Journal of Clinical Research in Pediatric Endocrinology

journal
https://www.readbyqxmd.com/read/29809159/the-role-of-irisin-insulin-and-leptin-in-maternal-and-fetal-interaction
#1
Deniz Ökdemir, Nihal Hatipoğlu, Selim Kurtoğlu, Ülkü Gül Siraz, Himmet Haluk Akar, Sabahattin Muhtaroğlu, Mehmet Serdar Kütük
OBJECTIVE: İnsulin is an important hormone for intrauterine growth, irisin is also an effective myokine in the regulation of physiological insulin resistance in pregnancy. Leptin and insulin are associated with fetal growth and adiposity. In this study, we aimed to investigate the relationship between irisin, insulin and leptin levels and maternal weight gain, newborn anthropometric measurements. METHODS: Eighty-four mothers and newborns were included in the study...
May 29, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29809158/slc34a3-intronic-deletion-in-an-iranian-kindred-with-hereditary-hypophosphatemic-rickets-with-hypercalciuria-and-review-of-reported-cases
#2
Shirin Hasani-Ranjbar, Hanieh Sadat Ejtahed, Mahsa M Amoli, Fatemeh Bitarafan, Mostafa Qorbani, Akbar Soltani, Bahareh Yarjoo
OBJECTIVE: Hereditary Hypophosphatemic Rickets with Hypercalciuria (HHRH) is a very rare inheritable hypophosphatemic rickets/osteomalacia characterized by decreased renal phosphate reabsorption, hypophosphatemia, vitamin D refractory rickets, hyperphosphaturia, hypercalciuria, elevated circulating 1, 25-dihydroxy vitamin D levels and low serum parathyroid hormone (PTH) levels, leading to growth retardation, limb deformities, bone pain, muscle weakness, rickets and osteomalacia. Biallelic mutations in SLC34A3/NPT2c gene are responsible for the occurrence of the disease...
May 29, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29789275/perceived-expressed-emotion-emotional-and-behavioral-problems-and-self-esteem-in-obese-adolescents-a-case-control-study
#3
Merve Çolpan, Şafak Eray, Erdal Eren, Ayşe Pınar Vural
OBJECTIVE: Obesity is a chronic disease which causes medical and psychiatric complications. Family climate is also a critical factor in the presence and treatment of obesity and comorbid psychiatric disorders. In our study, perceived expressed emotion (EE), psychopathology, self-esteem and emotional and behavioural problems among obese adolescents will be investigated by comparison with their non-obese peers. METHODS: This study was carried out with 49 obese adolescents and 47 non-obese adolescents as a control group...
May 23, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29789274/incidence-of-type-1-diabetes-in-children-aged-below-18-years-during-2013-2015-in-northwest-turkey
#4
Şükran Poyrazoğlu, Rüveyde Bundak, Zehra Yavaş Abalı, Hasan Önal, Sevil Sarıkaya, Abdurrahman Akgün, Serpil Baş, Saygın Abalı, Abdullah Bereket, Erdal Eren, Ömer Tarım, Ayla Güven, Metin Yıldız, Derya Karaman Aksakal, Ayşegül Yüksel, Gülcan Seymen Karabulut, Şükrü Hatun, Tolga Özgen, Yaşar Cesur, Mehmet Azizoğlu, Emine Dilek, Filiz Tütüncüler, Esra Papatya Çakır, Bahar Özcabı, Olcay Evliyaoğlu, Songül Karadeniz, Fatma Dursun, Semih Bolu, İlknur Arslanoğlu, Gül Yeşiltepe Mutlu, Heves Kırmızıbekmez, Pınar İşgüven, Ala Üstyol, Erdal Adal, Ahmet Uçar, Nurcan Cebeci, Didem Bezen, Çiğdem Binay, Serap Semiz, Hüseyin Anıl Korkmaz, Nihal Memioğlu, Elif Sagsak, Havva Nur Peltek, Melek Yıldız, Teoman Akçay, Serap Turan, Tülay Güran, Zeynep Atay, Neşe Akcan, Filiz Çizmecioğlu, Oya Ercan, Aydilek Dağdeviren, Firdevs Baş, Halim İşsever, Feyza Darendeliler
OBJECTIVE: To assess the incidence of type 1 diabetes mellitus (T1DM) in children under 18 years of age in the northwest region of Turkey during 2013-2015. METHODS: All newly diagnosed T1DM cases were recorded prospectively during 2013-2015. Total as well as gender and age group specific (0-4, 5-9, 10-14 and 15-17 age) mean incidences per 100.000 per year were calculated. RESULTS: There were 1773 patients diagnosed during 2013-2015 (588 cases in 2013, 592 cases in 2014, 593 cases in 2015)...
May 23, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29789273/insulin-resistance-is-related-to-psychiatric-disorders-among-obese-children
#5
Deniz Özalp Kızılay, Şermin Yalın Sapmaz, Semra Şen, Yekta Özkan, Betül Ersoy
OBJECTIVE: The current study aimed to investigate psychiatric consequences of obesity (OBy) and the relationship between metabolic syndrome components and psychiatric disorders in children. Our secondaryaim was to elucidate which of the anthropometric parameters or metabolic components were most strongly associated with psychiatric disorders. METHODS: The study included 88 obese(OB)and overweight (OW) children with a body mass index (BMI) greater than 85th percentile...
May 23, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29764793/evaluation-of-the-ovarian-reserve-in-adolescents-with-hashimoto-s-thyroiditis-using-serum-anti-m%C3%A3-llerian-hormone-levels
#6
Ezgi Özalp Akın, Zehra Aycan
OBJECTIVE: This study aims to evaluate the ovarian reserve of the adolescent girls with Hashimoto's thyroiditis (HT) with serum anti-müllerian hormone (AMH) levels and compare to healthy adolescents. It is hypothesized that HT decreases ovarian reserve and AMH levels are lower in the HT group. METHOD: Thirty HT patients aged between 10-18 years and 30 healthy girls as the control group are enrolled in this cross-sectional study. The mean serum AMH levels of the groups are compared using the Mann-Whitney U test...
May 16, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29739732/inherited-deletion-of-1q-hyperparathyroidism-and-signs-of-y-chromosomal-influence-in-a-patient-with-turner-syndrome
#7
Alejandro F Siller, Alex Shimony, Marwan Shinawi, Ina Amarillo, Louis P Dehner, Katherine Semenkovich, Ana María Arbeláez
We report a detailed phenotypic, cytogenetic, and molecular characterization of a patient diagnosed prenatally with Turner syndrome (TS). In addition to having typical TS clinical characteristics such as a webbed neck, high arched palate, and coarctation of the aorta, the patient had features less frequently seen in TS, including recurrent parathyroid adenomas, growth along the 75th-90th centiles on the TS height curve despite a minimal treatment with growth hormone, behavioral problems, and evidence of gonadal dysgenesis with testicular-like structures, such as seminiferous tubules lined by Sertoli cells and a contiguous nodule of Leydig cells...
May 9, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29739731/evaluation-of-the-efficacy-of-long-term-growth-hormone-theraphy-in-patients-with-hypochondroplas%C3%A4-a
#8
Tuğba Çetin, Zeynep Şıklar, Pınar Kocaay, Merih Berberoğlu
Hypochondroplasia is a cause of disproportionate short stature and characterized by slight clinical manifestations. The aim of this study was to evaluate the efficacy of long-term GH therapy in hypochondroplastic cases with inadequate response to GH simulation tests . In this study, six patients who had height SDS of -3.43 before the treatment and a mean age of 7.42 and received GH treatment at a dose of 0.2 mg / kg / week for a mean of 4.45 years were evaluated. As a result, a good accepted response was found in the first year in hypochondroplastic patients with findings of GH deficiency, but this increase was not found to be sufficient in the patients who achieved the final height...
May 9, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29739730/neonatal-hypopituitarism-diagnosis-and-treatment-approaches
#9
Selim Kurtoğlu, Ahmet Özdemir, Nihal Hatipoğlu
Hypopituitarism is defined as a decreased release of hypophysis hormones, which may be caused by pituitary gland disease or hypothalamus disease. Clinical findings for neonatal hypopituitarism depend on causes and hormonal deficiency type and degree. Patients may be asymptomatic or may demonstrate non-specific symptoms, but may still be under risk for development of hypophysis hormone deficiency with time. Anamnesis, physical examination, endocrinological, radiological and genetic evaluations are all important for early diagnosis and treatment...
May 9, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29726397/under-recognized-hypoparathyroidism-in-thalassemia
#10
Hataitip Tangngam, Pat Mahachoklertwattana, Preamrudee Poomthavorn, Ampaiwan Chuansumrit, Nongnuch Sirachainan, La-or Chailurkit, Patcharin Khlairit
OBJECTIVE: Symptomatic hypoparathyroidism [symptomatic hypocalcemia without elevated serum parathyroid hormone (PTH)] in patients with thalassemia is relatively rare. Asymptomatic mild hypocalcemia without elevated PTH which is considered hypoparathyroidism may be more common but under-recognized. METHODS: Sixty-six transfusion-dependent thalassemic patients, and 28 healthy controls were enrolled. Serum calcium (Ca), phosphate (P), creatinine (Cr), albumin, intact PTH, 25-hydroxyvitamin D (25-OHD), plasma intact fibroblast growth factor-23 (FGF-23), urine Ca, P and Cr were measured...
May 4, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29699389/a-synopsis-on-current-practice-in-the-diagnosis-and-management-of-patients-with-turner-syndrome-in-turkey-a-survey-of-18-pediatric-endocrinology-centers
#11
Ahmet Uçar, Ayhan Abacı, Özgür Pirgon, Bumin Dündar, Filiz Tütüncüler, Gönül Çatlı, Ahmet Anık, Aylin Kılınç Uğurlu, Atilla Büyükgebiz
Objective: A comprehensive survey was conducted courtesy of the Turkish Turner study group to evaluate the shortcomings of clinical care in patients with Turner syndrome (TS) in Turkey. Methods: A structured questionnaire prepared by the Turner study group in Turkey, which covers relevant aspects of the care of patients with TS, was sent to all pediatric endocrinology centers. Results: Eighteen centers (41%) returned the questionnaire. In the majority of the centers, diagnostic genetic testing, screening for Y chromosomal material, protocols regarding the timing and posology of growth hormone (GH) and estrogen, thrombophilia screening, fertility information, and screening for glucose intolerance, thyroid, and coeliac diseases in patients with TS were in line with the current consensus...
April 27, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29699378/use-of-vitamin-d-in-children-and-adults-frequently-asked-questions
#12
Gül Yeşiltepe Mutlu, Şükrü Hatun
In recent years, the increase in interest and use of vitamin D has been attributed mainly to the effects of vitamin D on the extra-skeletal effects and confusion about normal reference values for serum 25OHD. However, The Institute of Medicine (IOM), which determines daily intake of nutrients, vitamins and minerals in the United States, emphasizes that there is no additional benefit of having a 25OHD level above 20 ng/ml in terms of PTH suppression, calcium absorption and "fall risk". Taking into consideration that there has not been a significant increase in vitamin D deficiency and related conditions in Turkey over the past 5 years, it is not hard to suppose that this increase is due to declarations of doctors who have shown vitamin D as a "panacea’’ in media platforms...
April 27, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29687786/a-novel-mutation-of-amhr2-in-two-siblings-with-persistent-m%C3%A3-llerian-duct-syndrome
#13
Edip Unal, Ruken Yıldırım, Suat Tekin, Vasfiye Demir, Hüseyin Onay, Yusuf Kenan Haspolat
Persistent Müllerian Duct syndrome (PMDS) develops due to deficiency of anti-Müllerian hormone (AMH) or insensitivity of target organs to AMH in people with 46, XY karyotype. PMDS is characterized with normal male phenotype of external genital associated with persistence of Müllerian structures. The 2.5 years old male patient presented due to bilateral undescended testis. Karyotype was 46, XY. The amount of increase in testosterone following human chorionic gonadotropin (hCG) stimulation test was normal...
April 24, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29687783/subnormal-growth-velocity-and-related-factors-during-gnrh-analog-therapy-for-idiopathic-central-precocious-puberty
#14
Nursel Muratoğlu Şahin, Asiye Uğraş Dikmen, Semra Çetinkaya, Zehra Aycan
OBJECTIVE: Decline of subnormal growth velocity(GV) and related factors during gonadotropin-releasing hormone analog(GnRHa) therapy for idiopathic central precocious puberty(ICPP) are unclear. We investigated the incidence of subnormal growth velocity, associated factors in patients with GnRHa therapy for ICPP. METHODS: In this retrospective cohort study, the records of 50 girls were investigated, who had diagnosed ICPP and had started GnRHa treatment before the age of 8...
April 24, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29739729/congenital-hyperinsulinism-and-evolution-to-sulfonylurea-responsive-diabetes-later-in-life-due-to-a-novel-homozygous-p-l171f-abcc8-mutation
#15
Emregül Işık, Huseyin Demirbilek, Jayne A L Houghton, Sian Ellard, Sarah E Flanagan, Khalid Hussain
BACKGROUND: Congenital hyperinsulinism (CHI) is the most common cause of persistent hypoglycemia in infants and children. Recessive inactivating mutations in the ABCC8 and KCNJ11 genes account for approximately 50 % of all CHI cases. Hyperinsulinaemic hypoglycaemia (HH) in infancy and diabetes in later life have been reported in subjects with HNF1A , HNF4A and ABCC8 mutations. CASE REPORT: Herein, we present a child who was diagnosed with CHI at birth, then developed diabetes mellitus at the age of 9 years due to a novel homozygous missense, p...
March 29, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29595517/parental-perception-of-terminology-of-disorders-of-sex-development-in-western-turkey-running-head-parental-perception-of-dsd-terminology
#16
Sibel Tiryaki, Ali Tekin, Ismail Yagmur, Samim Özen, Burcu Özbaran, Damla Gökşen, Şükran Darcan, İbrahim Ulman, Ali Avanoğlu
OBJECTIVE: "Disorders of sex development (DSD)" is a nomenclature proposed to defeat the discomfort of families and patients and has found worldwide usage. The aim of this study is addressing the perception and usage of terminology among the parents of DSD patients in a tertiary center in western Turkey. METHODS: The records of the DSD council between years 2008-2015 were reviewed retrospectively and data including details of the management process, patient characteristics and follow-up details were noted...
March 29, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29595516/a-rare-cause-of-congenital-adrenal-hyperplasia-clinical-and-genetic-findings-and-follow-up-characteristics-of-six-patients-with-17-hydroxylase-deficiency-and-two-novel-mutations
#17
Aslı Derya Kardelen, Güven Toksoy, Firdevs Baş, Zehra Yavaş Abalı, Genco Gençay, Şükran Poyrazoğlu, Rüveyde Bundak, Umut Altunoğlu, Şahin Avcı, Adam Najaflı, Oya Uyguner, Birsen Karaman, Seher Başaran, Feyza Darendeliler
BACKGROUND: 17-α-hydroxylase/17,20 lyase deficiency (17OHD) is a rare form of congenital adrenal hyperplasia (CAH), characterized by hypertension and varying degrees of ambiguous genitalia and delayed pu-berty. The disease is associated with bi-allelic mutations in the CYP17A1 gene located on chromosome 10q24.3. We aimed to present clinical and genetic findings and follow-up and treatment of 17-OHD patients. PATIENTS AND METHODS: We evaluated six patients with 17OHD from five families at presentation and at follow up...
March 29, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29792016/erratum
#18
(no author information available yet)
No abstract text is available yet for this article.
June 1, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29537377/effectiveness-of-continuous-subcutaneous-insulin-infusion-pump-therapy-during-five-years-of-treatment-on-metabolic-control-in-children-and-adolescents-with-type-1-diabetes-mellitus
#19
Özlem Korkmaz, Günay Demir, Hafize Çetin, İlkin Mecidov, Yasemin Atik Altınok, Samim Özen, Şükran Darcan, Damla Gökşen
OBJECTIVE: To compare continuous subcutaneous insulin infusion (CSII) therapy with multiple daily insulin (MDI) therapy on metabolic control in children and adolescents with type 1 diabetes mellitus (T1DM) over the long term. METHODS: Fifty-two T1DM patients treated with CSII and monitored for at least one year prior to and at least five years following CSII were included. Thirty-eight age and sex-matched MDI controls with a 5-year follow up were recruited. RESULTS: Mean age of the subjects, duration of diabetes and CSII therapy were 17...
June 1, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29022558/klinefelter-syndrome-in-childhood-variability-in-clinical-and-molecular-findings
#20
Neşe Akcan, Şükran Poyrazoğlu, Firdevs Baş, Rüveyde Bundak, Feyza Darendeliler
OBJECTIVE: Klinefelter syndrome (KS) is the most common (1/500–1/1000) chromosomal disorder in males, but only 10% of cases are identified in childhood. This study aimed to review the data of children with KS to assess the age and presenting symptoms for diagnosis, clinical and laboratory findings, together with the presence of comorbidities. METHODS: Twenty-three KS patients were analyzed retrospectively. Age at admission, presenting symptoms, comorbid problems, height, weight, pubertal status, biochemical findings, hormone profiles, bone mineral density and karyotype were evaluated...
June 1, 2018: Journal of Clinical Research in Pediatric Endocrinology
journal
journal
42725
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"