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International Journal of Biomaterials

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https://www.readbyqxmd.com/read/29434640/natural-composite-reinforced-by-lontar-borassus-flabellifer-fiber-an-experimental-study-on-open-hole-tensile-strength
#1
Jefri Bale, Kristomus Boimau, Marselinus Nenobesi
A research has been conducted in the present study to investigate the effect of hole configuration on tensile strength of lontar fiber-reinforced composites. The lontar fiber-reinforced composites used in this study were produced by hand lay-up process. The lontar fiber-reinforced composites consist of short random fiber of 5 cm that contains 32% of nominal fiber volume as the reinforcement and unsaturated polyester as the matrix. The results show that the differences of hole configuration have an effect on tensile strength of lontar fiber-reinforced composites...
2017: International Journal of Biomaterials
https://www.readbyqxmd.com/read/29250114/tissue-engineered-vascular-graft-of-small-diameter-based-on-electrospun-polylactide-microfibers
#2
P V Popryadukhin, G I Popov, G Yu Yukina, I P Dobrovolskaya, E M Ivan'kova, V N Vavilov, V E Yudin
Tubular vascular grafts 1.1 mm in diameter based on poly(L-lactide) microfibers were obtained by electrospinning. X-ray diffraction and scanning electron microscopy data demonstrated that the samples treated at T = 70°C for 1 h in the fixed state on a cylindrical mandrel possessed dense fibrous structure; their degree of crystallinity was approximately 44%. Strength and deformation stability of these samples were higher than those of the native blood vessels; thus, it was possible to use them in tissue engineering as bioresorbable vascular grafts...
2017: International Journal of Biomaterials
https://www.readbyqxmd.com/read/29250113/encapsulation-of-nicardipine-hydrochloride-and-release-from-biodegradable-poly-d-l-lactic-co-glycolic-acid-microparticles-by-double-emulsion-process-effect-of-emulsion-stability-and-different-parameters-on-drug-entrapment
#3
Nopparuj Soomherun, Narumol Kreua-Ongarjnukool, Sorayouth Chumnanvej, Saowapa Thumsing
Poly(D,L-lactic-co-glycolic acid) (PLGA) is an important material used in drug delivery when controlled release is required. The purpose of this research is to design and characterize PLGA microparticles (PLGA MPs) implants for the controlled release of nicardipine hydrochloride (NCH) in vitro. This study used the water-in-oil-in-water (w1/o/w2) double emulsion and solvent diffusion/evaporation approach to prepare PLGA MPs. Optimal processing conditions were found, such as polymer content, surfactant type, stabilizer concentration, inner and outer aqueous phase volumes, and stirring speed...
2017: International Journal of Biomaterials
https://www.readbyqxmd.com/read/29093738/comparative-effectiveness-of-bone-grafting-using-xenograft-freeze-dried-cortical-bovine-allograft-freeze-dried-cortical-new-zealand-white-rabbit-xenograft-hydroxyapatite-bovine-and-xenograft-demineralized-bone-matrix-bovine-in-bone-defect-of-femoral-diaphysis
#4
Ferdiansyah Mahyudin, Dwikora Novembri Utomo, Heri Suroto, Tri Wahyu Martanto, Mouli Edward, Imelda Lumban Gaol
Autogenous bone graft is gold standard in treating bone defects, but it might have difficulty in corporation and rejection reaction. This study is to compare the effectiveness among freeze-dried xenograft, freeze-dried allograft, hydroxyapatite xenograft, and demineralized bone matrix xenograft as bone graft to fill bone defect in femoral diaphysis of white rabbit. Thirty male New Zealand white rabbits were distributed into five groups. Bone defect was filled correspondingly with xenograft freeze-dried cortical bovine, allograft freeze-dried cortical New Zealand white rabbit, xenograft hydroxyapatite bovine, and xenograft demineralized bone matrix bovine...
2017: International Journal of Biomaterials
https://www.readbyqxmd.com/read/29056968/effect-of-injection-molding-melt-temperatures-on-plga-craniofacial-plate-properties-during-in-vitro-degradation
#5
Liliane Pimenta de Melo, Gean Vitor Salmoria, Eduardo Alberto Fancello, Carlos Rodrigo de Mello Roesler
The purpose of this article is to present mechanical and physicochemical properties during in vitro degradation of PLGA material as craniofacial plates based on different values of injection molded temperatures. Injection molded plates were submitted to in vitro degradation in a thermostat bath at 37 ± 1°C by 16 weeks. The material was removed after 15, 30, 60, and 120 days; then bending stiffness, crystallinity, molecular weights, and viscoelasticity were studied. A significant decrease of molecular weight and mechanical properties over time and a difference in FT-IR after 60 days showed faster degradation of the material in the geometry studied...
2017: International Journal of Biomaterials
https://www.readbyqxmd.com/read/28947903/influence-of-vanadium-4-and-5-ions-on-the-differentiation-and-activation-of-human-osteoclasts
#6
Matthias A König, Oliver P Gautschi, Hans-Peter Simmen, Luis Filgueira, Dieter Cadosch
BACKGROUND: In the pathophysiology of implant failure, metal ions and inflammation-driven osteoclasts (OC) play a crucial role. The aim of this study was to investigate whether vanadium (V) ions induce differentiation of monocytic OC precursors into osteoresorptive multinucleated cells. In addition, the influence of V ions on the activation and function of in vitro generated OC was observed. METHODS: Human monocytes and osteoclasts were isolated from peripheral blood monocytic cells (PBMCs)...
2017: International Journal of Biomaterials
https://www.readbyqxmd.com/read/28912813/silicone-substrate-with-collagen-and-carbon-nanotubes-exposed-to-pulsed-current-for-msc-osteodifferentiation
#7
Daniyal Jamal, Roche C de Guzman
Autologous human adipose tissue-derived mesenchymal stem cells (MSCs) have the potential for clinical translation through their induction into osteoblasts for regeneration. Bone healing can be driven by biophysical stimulation using electricity for activating quiescent adult stem cells. It is hypothesized that application of electric current will enhance their osteogenic differentiation, and addition of conductive carbon nanotubes (CNTs) to the cell substrate will provide increased efficiency in current transmission...
2017: International Journal of Biomaterials
https://www.readbyqxmd.com/read/28848605/influence-of-processing-conditions-on-the-mechanical-behavior-and-morphology-of-injection-molded-poly-lactic-co-glycolic-acid-85-15
#8
Liliane Pimenta de Melo, Gean Vitor Salmoria, Eduardo Alberto Fancello, Carlos Rodrigo de Mello Roesler
Two groups of PLGA specimens with different geometries (notched and unnotched) were injection molded under two melting temperatures and flow rates. The mechanical properties, morphology at the fracture surface, and residual stresses were evaluated for both processing conditions. The morphology of the fractured surfaces for both specimens showed brittle and smooth fracture features for the majority of the specimens. Fracture images of the notched specimens suggest that the surface failure mechanisms are different from the core failure...
2017: International Journal of Biomaterials
https://www.readbyqxmd.com/read/28814954/intrinsic-osteoinductivity-of-porous-titanium-scaffold-for-bone-tissue-engineering
#9
Maryam Tamaddon, Sorousheh Samizadeh, Ling Wang, Gordon Blunn, Chaozong Liu
Large bone defects and nonunions are serious complications that are caused by extensive trauma or tumour. As traditional therapies fail to repair these critical-sized defects, tissue engineering scaffolds can be used to regenerate the damaged tissue. Highly porous titanium scaffolds, produced by selective laser sintering with mechanical properties in range of trabecular bone (compressive strength 35 MPa and modulus 73 MPa), can be used in these orthopaedic applications, if a stable mechanical fixation is provided...
2017: International Journal of Biomaterials
https://www.readbyqxmd.com/read/28694826/magnesium-oxide-nanoparticles-reinforced-electrospun-alginate-based-nanofibrous-scaffolds-with-improved-physical-properties
#10
R T De Silva, M M M G P G Mantilaka, K L Goh, S P Ratnayake, G A J Amaratunga, K M Nalin de Silva
Mechanically robust alginate-based nanofibrous scaffolds were successfully fabricated by electrospinning method to mimic the natural extracellular matrix structure which benefits development and regeneration of tissues. Alginate-based nanofibres were electrospun from an alginate/poly(vinyl alcohol) (PVA) polyelectrolyte complex. SEM images revealed the spinnability of the complex composite nanofibrous scaffolds, showing randomly oriented, ultrafine, and virtually defects-free alginate-based/MgO nanofibrous scaffolds...
2017: International Journal of Biomaterials
https://www.readbyqxmd.com/read/28611845/novel-nanotechnology-of-tio2-improves-physical-chemical-and-biological-properties-of-glass-ionomer-cement
#11
Daniela Dellosso Cibim, Miki Taketomi Saito, Priscila Alves Giovani, Ana Flávia Sanches Borges, Vanessa Gallego Arias Pecorari, Orisson Ponce Gomes, Paulo Noronha Lisboa-Filho, Francisco Humberto Nociti-Junior, Regina Maria Puppin-Rontani, Kamila Rosamilia Kantovitz
The aim of this study was to assess the performance of glass ionomer cement (GIC) added with TiO2 nanotubes. TiO2 nanotubes [3%, 5%, and 7% (w/w)] were incorporated into GIC's (Ketac Molar EasyMix™) powder component, whereas unblended powder was used as control. Physical-chemical-biological analysis included energy dispersive spectroscopy (EDS), surface roughness (SR), Knoop hardness (SH), fluoride-releasing analysis, cytotoxicity, cell morphology, and extracellular matrix (ECM) composition. Parametric or nonparametric ANOVA were used for statistical comparisons (α ≤ 0...
2017: International Journal of Biomaterials
https://www.readbyqxmd.com/read/28592972/fabrication-of-polycaprolactone-polyurethane-loading-conjugated-linoleic-acid-and-its-antiplatelet-adhesion
#12
Ho Hieu Minh, Nguyen Thi Hiep, Nguyen Dai Hai, Vo Van Toi
Polycaprolactone/polyurethane (PCL/PU) fibrous scaffold was loaded with conjugated linoleic acid (CLA) by electrospinning method to improve the hemocompatibility of the polymeric surface. Fourier Transform Infrared Spectroscopy (FT-IR) analysis and Scanning Electron Microscopy (SEM) observation were employed to characterize the chemical structure and the changing morphology of electrospun PCL/PU and PCL/PU loaded with CLA (PCL/PU-CLA) scaffolds. Platelet adhesion and whole blood clot formation tests were used to evaluate the effect of CLA on antithrombotic property of PCL/PU-CLA scaffold...
2017: International Journal of Biomaterials
https://www.readbyqxmd.com/read/28572823/stabilisation-of-collagen-sponges-by-glutaraldehyde-vapour-crosslinking
#13
Yong Y Peng, Veronica Glattauer, John A M Ramshaw
Glutaraldehyde is a well-recognised reagent for crosslinking and stabilising collagens and other protein-based materials, including gelatine. In some cases, however, the use of solutions can disrupt the structure of the material, for example, by causing rapid dispersion or distortions from surface interactions. An alternative approach that has been explored in a number of individual cases is the use of glutaraldehyde vapour. In this study, the effectiveness of a range of different glutaraldehyde concentrations in the reservoir providing vapour, from 5% to 25% (w/v), has been explored at incubation times from 5 h to 48 h at room temperature...
2017: International Journal of Biomaterials
https://www.readbyqxmd.com/read/28424734/influence-of-teeth-preparation-finishing-on-the-adaptation-of-lithium-disilicate-crowns
#14
Bruna Salamoni Sinhori, Mauro Amaral Caldeira de Andrada, Guilherme Carpena Lopes, Sylvio Monteiro Junior, Luiz Narciso Baratieri
The polishing step of teeth preparations for crowns is a step often performed, so that there is an increased time during the clinical procedure. The aim of this study is to evaluate the marginal and internal adaptation of all-ceramic CAD/CAM lithium disilicate crowns in polished preparations for crown and nonpolished preparations for crowns. For this purpose, 20 first molars were selected, which were divided into two groups (n = 10) G1, teeth that received surface roughening similar to preparation without polishing, and G2 (control), polished preparations...
2017: International Journal of Biomaterials
https://www.readbyqxmd.com/read/28331495/development-and-in-vitro-evaluation-of-liposomes-using-soy-lecithin-to-encapsulate-paclitaxel
#15
Thi Lan Nguyen, Thi Hiep Nguyen, Dai Hai Nguyen
The formulation of a potential delivery system based on liposomes (Lips) formulated from soy lecithin (SL) for paclitaxel (PTX) was achieved (PTX-Lips). At first, PTX-Lips were prepared by thin film method using SL and cholesterol and then were characterized for their physiochemical properties (particle size, polydispersity index, zeta potential, and morphology). The results indicated that PTX-Lips were spherical in shape with a dynamic light scattering (DLS) particle size of 131 ± 30.5 nm. Besides, PTX was efficiently encapsulated in Lips, 94...
2017: International Journal of Biomaterials
https://www.readbyqxmd.com/read/27965710/new-biofunctional-loading-of-natural-antimicrobial-agent-in-biodegradable-polymeric-films-for-biomedical-applications
#16
Bakhtawar Ghafoor, Murtaza Najabat Ali, Umar Ansari, Muhammad Faraz Bhatti, Mariam Mir, Hafsah Akhtar, Fatima Darakhshan
The study focuses on the development of novel Aloe vera based polymeric composite films and antimicrobial suture coatings. Polyvinyl alcohol (PVA), a synthetic biocompatible and biodegradable polymer, was combined with Aloe vera, a natural herb used for soothing burning effects and cosmetic purposes. The properties of these two materials were combined together to get additional benefits such as wound healing and prevention of surgical site infections. PVA and Aloe vera were mixed in a fixed quantity to produce polymer based films...
2016: International Journal of Biomaterials
https://www.readbyqxmd.com/read/27656212/fracture-resistance-of-endodontically-treated-maxillary-premolars-restored-by-various-direct-filling-materials-an-in-vitro-study
#17
Jozef Mincik, Daniel Urban, Silvia Timkova, Renata Urban
The aim of this study is to compare the effect of various restorative materials on fracture resistance in maxillary premolars. Premolars (n = 64) with no restorations or cracks were selected. MOD cavities were prepared considering the buccolingual width to be equal to half of the intercuspal distance. The specimens were randomly divided into 8 groups, 8 specimens each: group A intact teeth, group B unfilled cavity, group C composite made by oblique layering technique, group D composite with 2 mm cusp coverage, group E bulk-filled posterior composite, group F glass-ionomer, group G amalgam, and group H composite with proximal boxes...
2016: International Journal of Biomaterials
https://www.readbyqxmd.com/read/27340405/silver-nanoparticles-biosynthesis-using-an-atcc-reference-strain-of-pseudomonas-aeruginosa-and-activity-as-broad-spectrum-clinical-antibacterial-agents
#18
Melisa A Quinteros, Ivana M Aiassa Martínez, Pablo R Dalmasso, Paulina L Páez
Currently, the biosynthesis of silver-based nanomaterials attracts enormous attention owing to the documented antimicrobial properties of these ones. This study reports the extracellular biosynthesis of silver nanoparticles (Ag-NPs) using a Pseudomonas aeruginosa strain from a reference culture collection. A greenish culture supernatant of P. aeruginosa incubated at 37°C with a silver nitrate solution for 24 h changed to a yellowish brown color, indicating the formation of Ag-NPs, which was confirmed by UV-vis spectroscopy, transmission electron microscopy, and X-ray diffraction...
2016: International Journal of Biomaterials
https://www.readbyqxmd.com/read/27293439/shear-bond-strengths-between-three-different-yttria-stabilized-zirconia-dental-materials-and-veneering-ceramic-and-their-susceptibility-to-autoclave-induced-low-temperature-degradation
#19
Manoti Sehgal, Akshay Bhargava, Sharad Gupta, Prateek Gupta
A study was undertaken to evaluate the effect of artificial aging through steam and thermal treatment as influencing the shear bond strength between three different commercially available zirconia core materials, namely, Upcera, Ziecon, and Cercon, layered with VITA VM9 veneering ceramic using Universal Testing Machine. The mode of failure between zirconia and ceramic was further analyzed as adhesive, cohesive, or mixed using stereomicroscope. X-ray diffraction and SEM (scanning electron microscope) analysis were done to estimate the phase transformation (m-phase fraction) and surface grain size of zirconia particles, respectively...
2016: International Journal of Biomaterials
https://www.readbyqxmd.com/read/27293438/novel-vanadium-loaded-ordered-collagen-scaffold-promotes-osteochondral-differentiation-of-bone-marrow-progenitor-cells
#20
Ana M Cortizo, Graciela Ruderman, Flavia N Mazzini, M Silvina Molinuevo, Ines G Mogilner
Bone and cartilage regeneration can be improved by designing a functionalized biomaterial that includes bioactive drugs in a biocompatible and biodegradable scaffold. Based on our previous studies, we designed a vanadium-loaded collagen scaffold for osteochondral tissue engineering. Collagen-vanadium loaded scaffolds were characterized by SEM, FTIR, and permeability studies. Rat bone marrow progenitor cells were plated on collagen or vanadium-loaded membranes to evaluate differences in cell attachment, growth and osteogenic or chondrocytic differentiation...
2016: International Journal of Biomaterials
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