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Journal of Clinical and Aesthetic Dermatology

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https://www.readbyqxmd.com/read/28979665/1340nm-laser-therapy-for-onychomycosis-negative-results-of-prospective-treatment-of-72-toenails-and-a-literature-review
#1
Graciela Araújo Do Espírito-Santo, Diniz Pereira Leite, Hugo Dias Hoffmann-Santos, Luciana Basili Dias, Rosane Christine Hahn
Onychomycosis is an infection of the nail plate by fungal microorganisms. This infection has an important social impact on women and men and poses a major challenge for its treatment. The traditional treatment of onychomycosis involves the use of topical and oral antifungal agents. However, the presence of adverse effects frequently associated with oral antifungals, their high cost, and their potential interactions with other drugs reflect some of the problems associated with conventional therapy. The current report details the evaluation of a 1340nm laser as monotherapy for toenails affected by onychomycosis...
August 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28979664/oily-skin-a-review-of-treatment-options
#2
REVIEW
Dawnielle C Endly, Richard A Miller
One of the most common dermatologic concerns is oily skin, and the demand for effective treatment options is ever apparent. This review article addresses numerous topical treatment options such as retinoids, olumacostat glasaretil, and various cosmeceutical agents. several systemic and procedural techniques that incorporate isotretinoin, spironolactone, oral contraceptives, botulinum toxin, photodynamic therapy, and lasers are reviewed as well. Each treatment option is analyzed in terms of the proposed mechanism of action, efficacy reported in the literature, and potential adverse effects...
August 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28979663/finger-pad-squamous-cell-carcinoma-report-of-squamous-cell-carcinoma-of-the-distal-palmar-digit-and-review-of-associated-risk-factors-mimickers-and-treatment-of-squamous-cell-carcinoma-of-ventral-hand-digits
#3
Philip R Cohen, S Brian Jiang
BACKGROUND: Squamous cell carcinoma of the palmar digits is rare. PURPOSE: The authors describe a man with squamous cell carcinoma of the pulp of his left fourth finger, and review the risk factors that may be associated with squamous cell carcinoma development on the ventral digits of the hand. the authors also summarize the clinical differential diagnoses and treatment of squamous cell carcinoma at this location. METHODS: the authors retrospectively reviewed the literature using PubMed and searched for the following terms: squamous cell carcinoma, squamous cell carcinoma in situ, finger, thumb, palmar, and ventral...
August 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28979662/topical-treatment-of-aging-hands-brief-report
#4
Wendy E Roberts, Lora Colvan, Vincent Gotz
Rejuvenation of aging hands is becoming increasingly important to physicians and their patients. While a variety of invasive treatments are available, topical products that improve manifestations of aging hands are needed. In this brief report, the efficacy of a topical product containing urea, lipids, sodium copper chlorophyllin complex, antioxidants, and humectants was assessed in subjects with moderate-to-severe photodamage of the hands.
August 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28979661/a-prospective-pilot-clinical-trial-to-evaluate-the-efficacy-and-safety-of-topical-therapy-with-ingenol-mebutate-gel-0-015-for-actinic-keratosis-on-an-expanded-area-of-the-chest
#5
Douglas C Wu, Isabella Guiha, Mitchel P Goldman
BACKGROUND: Ingenol mebutate gel 0.05% once daily for two consecutive days provides high clearance rates for actinic keratosis on a 25cm(2) area of the chest. However, it may cause intense local skin responses. OBJECTIVE: The objective of this study was to determine whether a lower dose of ingenol mebutate gel 0.015% could clear actinic keratosis on the chest with acceptable tolerability and a possible beneficial effect on photodamage and cosmesis. DESIGN: This was a noncomparative, open-label study (NCT02446223)...
August 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28979660/treatment-of-freckles-using-a-fractional-nonablative-2940nm-erb-yag-laser-in-a-series-of-asian-patients
#6
Brian Tian
OBJECTIVE: The purpose of this study was to demonstrate a novel, effective, and safe way to utilize the Erb:YAG laser to clear freckles in Type III/IV Asian skin. DESIGN: This was a prospective study. SETTING: The setting was a Singapore-based clinic. PARTICIPANTS: Participants included five women, aged 25 to 38 years, three with Skin Type III and two with Skin Type IV. All of them had freckles. MEASUREMENTS: Photographs were taken pretreatment and one month after laser treatment. Three independent physicians evaluated the photographs using a grading system...
August 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28979659/pan-asian-consensus-key-recommendations-for-adapting-the-world-congress-of-dermatology-consensus-on-combination-treatment-with-injectable-fillers-toxins-and-ultrasound-devices-in-asian-patients
#7
Yates Y Y Chao, Chiranjiv Chhabra, Niamh Corduff, Sabrina Guillen Fabi, Martina Kerscher, Stephanie C K Lam, Tatjana Pavicic, Berthold Rzany, Peter H L Peng, Atchima Suwanchinda, Fang-Wen Tseng, Kyle K Seo
BACKGROUND. The demand for minimally invasive aesthetic procedures has driven requests by physicians for guidance on their use in Asian patients, who have unique cultural preferences, social trends, and anatomy. However, few guidelines exist, particularly on combination treatment strategies for different facial shapes or indications such as the modification of face shapes to the "oval ideal."Physicians must, therefore, apply Caucasian patient-optimized guidelines to their Asian patients. METHODS. Eleven specialists developed a consensus on the use of botulinum toxin A (BoNT-A), calcium hydroxylapatite (CaHA) and hyaluronic acid (HA) fillers, and microfocused ultrasound with visualization (MFU-V) devices in Asian patients on upper-, middle-, and lower-face indications, including strategies to modify different facial shapes to the oval shape...
August 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28979658/radiation-therapy-for-the-adjunctive-treatment-of-surgically-excised-keloids-a-review
#8
REVIEW
Nikoo Cheraghi, Armand Cognetta, David Goldberg
BACKGROUND: Radiotherapy has been used historically to treat a wide variety of dermatologie conditions, including nonmelanoma skin cancers, lymphomas, and inflammatory skin conditions. Recently, radiotherapy has been used increasingly as a valuable tool in the postsurgical treatment of large or recalcitrant keloids. OBJECTIVE: The objective of this review was to explore the use of radiation therapy as an adjuvant to surgically excised keloids. DESIGN: A PubMed search of all published English literature regarding the applications of radiotherapy for the treatment of keloids was performed using a combination of keywords including radiation, radiotherapy, brachytherapy, electron beam, superficial radiation, orthovoltage radiation, and keloid...
August 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28979657/nonablative-fractional-laser-resurfacing-in-skin-of-color-evidence-based-review
#9
REVIEW
Shivani B Kaushik, Andrew F Alexis
Background: Nonablative laser resurfacing represents one of the major advances in procedural dermatology over the past decade. However, its use in darker skin types is limited by safety concerns and a relative lack of available data. Aim: To provide evidence-based recommendations for the use of fractional lasers in darker skin types. Evidence review: A broad literature search of PubMed/Medline database was conducted in April 2016 using the term fractional lasers. A free text search of keywords including fractional resurfacing, nonablative lasers, skin type, skin of color, ethnic skin, Fitzpatrick skin type, Asian skin, African Americans, Afro-Caribbean, and Hispanics was also executed...
June 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28979656/treatment-of-actinic-purpura
#10
REVIEW
Roger I Ceilley
Mature skin is prone to bruising, resulting in a condition known as actinic purpura, characterized by unsightly ecchymosis and purple patches. Similar to other skin conditions, the incidence of actinic purpura increases with advancing age and occurs with equal frequency among men and women. The unsightly appearance of actinic purpura may be a source of emotional distress among the elderly. A new product has been formulated specifically for the treatment of actinic purpura. This product contains retinol, α-hydroxy acids, arnica oil, ceramides, niacinamide, and phytonadione, which effectively treat actinic purpura by improving local circulation, thickening the skin, and repairing the skin barrier...
June 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28979655/treatment-of-moderate-to-severe-acne-vulgaris-in-a-hispanic-population-a-post-hoc-analysis-of-the-efficacy-and-tolerability-of-clindamycin-1-2-benzoyl-peroxide-3-75-gel
#11
Andrew F Alexis, Fran Cook-Bolden, Tina Lin
Background: Acne vulgaris (acne) is highly prevalent in the Hispanic population as it is in other racial/ethnic groups. While nuances in the presentation, quality-of-life impact, and approach to therapy of acne have been reported in various racial ethnic groups and skin types, data on the Hispanic population are limited, and yet they are the fastest growing population in the United States. Potential for irritation, dryness, and pigmentary alteration (due to acne and/or treatment) are key concerns in the management of acne in Hispanic populations...
June 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28979654/the-burden-of-illness-of-erythematotelangiectatic-rosacea-and-papulopustular-rosacea-findings-from-a-web-based-survey
#12
James Q Del Rosso, Emil A Tanghetti, Hilary E Baldwin, David A Rodriguez, Ilia L Ferrusi
Objective: Evaluate patients' perceptions of rosacea symptoms and treatments. Design: Cross-sectional, web-based survey conducted from May 8 to July 1,2015. Setting: E-mail invitation. Participants: Male and female adults in the United States who self-reported having a physician's diagnosis of rosacea. Measurements: Sociodemographic and clinical characteristics were collected for eligible respondents using the Self-Assessment of Rosacea Facial Redness scale and the Symptom Assessment for Rosacea Facial Bumps and Pimples questionnaire...
June 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28979653/topical-anti-estrogen-therapy-to-treat-melasma
#13
Philip R Cohen
No abstract text is available yet for this article.
June 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28670359/red-dot-basal-cell-carcinoma
#14
Philip R Cohen
Red dot basal cell carcinoma, a distinctive morphologic variant of basal cell carcinoma that presents as a small red macule (dot) or papule, is described on a woman's thigh. A high index of suspicion is necessary to consider the diagnosis since the tumor mimics a telangiectasia or an angioma.
May 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28670358/aesthetic-treatment-of-bruxism
#15
REVIEW
Shino Bay Aguilera, Liza Brown, Viviana Andrea Perico
Bruxism is a diurnal or nocturnal parafunctional activity that includes unconscious clenching, grinding, or bracing of the teeth. An extensive medical history should be taken in these patients so proper diagnosis can be made. Habits such as biting the tongue, cheeks or lips, chewing gum or eating seeds for many hours per day, biting nails, and/or biting hard objects, will cause and/or exacerbate pre-existing bruxism. The etiology of bruxism is uncertain, but it is hypothesized to be associated with genetic, structural, and psychosocial factors...
May 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28670357/raising-awareness-among-healthcare-providers-about-epidermolysis-bullosa-and-advancing-toward-a-cure
#16
REVIEW
Aaron Tabor, Joseph V Pergolizzi, Guy Marti, John Harmon, Bernard Cohen, Jo Ann Lequang
Objective: Epidermolysis bullosa (EB) is an orphan disease that affects about half a million people worldwide, but may not be familiar to all clinicians. The authors' goal was to present a short description of this condition and current research in the form of a narrative review. Methods: The authors reviewed the literature on epidermolysis bullosa in order to describe the condition and current genetic research. Results: There are at least 31 subtypes of EB, including junctional EB, dystrophic EB, and Kindler syndrome...
May 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28670356/a-prospective-randomized-double-blind-split-face-clinical-trial-comparing-the-efficacy-of-two-topical-human-growth-factors-for-the-rejuvenation-of-the-aging-face
#17
Douglas C Wu, Mitchel P Goldman
Background: Cosmeceutical products represent an increasingly important therapeutic option for anti-aging and rejuvenation, either used alone or in combination with dermatologic surgical procedures. Among this group of products, topical growth factors have demonstrated efficacy in randomized, controlled clinical trials. However, comparisons between different products remain uncommon. Objective: The objective of this randomized, double-blind, split-face clinical trial was to compare two different topical growth factor formulations derived from either human fibroblasts or human adipose tissue derived mesenchymal stem cells...
May 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28670355/a-retrospective-study-of-non-thermal-laser-therapy-for-the-treatment-of-toenail-onychomycosis
#18
Kerry Zang, Robert Sullivan, Steven Shanks
Objective: The objective of this study was to assess the efficacy of non-thermal laser therapy for treating toenail onychomycosis. Design: This retrospective study analyzed the results of three nonrandomized, open-label studies. The device used was a 635nm/405nm dual-diode laser. Affected toenails were treated for 12 minutes weekly for 2 or 4 weeks. Setting: Treatments occurred in clinic and private office settings. Participants: Subjects with onychomycosis-infected toenails were enrolled. Measurements: Fifty great toenails were included in the analysis based on visually identifiable onychomycosis; thickened, discolored nail plate; and confirmed etiology of onychomycosis...
May 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28670354/psychosocial-impact-of-postinflammatory-hyperpigmentation-in-patients-with-acne-vulgaris
#19
Kavita Darji, Reena Varade, Daniel West, Eric S Armbrecht, Mary A Guo
Background: Acne vulgaris is a common, often socially distressing skin condition primarily seen in young adults. Quality of life studies have shown that people with acne are more introverted with increased social setting anxiety compared to a control group. Unfortunately, patients with acne may have residual postinflammatory hyperpigmentation, amplifying impaired psychosocial effects. Objective: To quantify the impact of postinflammatory hyperpigmentation in patients with acne using a psychometric scale. Design: A clinic-based survey was conducted among US adults with facial acne and postinflammatory hyperpigmentation...
May 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28458775/vulvar-asymmetry-due-to-silicone-migration-and-granulomatous-immune-response-following-injection-for-buttock-augmentation
#20
David B Harker, Jake E Turrentine, Seemal R Desai
A 34-year-old woman was referred to the authors' dermatology clinic for evaluation of right labial swelling and dyspareunia. Her symptoms began after receiving a liquid silicone injection into the buttocks at a cosmetic plastic surgery clinic that was operating illegally by an unlicensed provider. A single prior debulking surgery had produced only temporary relief of symptoms, and the swelling returned. Work-up including magnetic resonance imaging and skin biopsy revealed migration of the injected silicone from her buttock to the subcutaneous tissue of the right labia majora, with an associated granulomatous immune response to the silicone...
April 2017: Journal of Clinical and Aesthetic Dermatology
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