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Journal of Clinical and Aesthetic Dermatology

Martyn King, Cormac Convery, Emma Davies
No abstract text is available yet for this article.
June 2018: Journal of Clinical and Aesthetic Dermatology
Lily I Jiang, Peter D Hino, Lydia Parker, Thomas J Stephens, John Mccook, Vincent Gotz
Objective: The objective of this study was to assess clinical safety and efficacy of a novel acne treatment regimen in adult women. Methods: Participants in the study included an ethnically diverse group of adult women (n=24) with mild-to-moderate acne who were treated twice daily with a topical regimen (cleanser, acne cream, and rebalancing gel) for eight weeks. Following baseline assessments, subjects returned to clinic at Weeks 2, 4, and 8 for clinical assessments and self-assessment questionnaires. Results: Twenty-one of the 24 enrolled women completed the eight-week clinical trial...
June 2018: Journal of Clinical and Aesthetic Dermatology
Benji Dhillon, Tapan Patel
Objective: The goal of this study was to evaluate the safety and the efficacy of the SlimME™ (Lumenis AB, Lumenis, Israel) ultrasound device for noninvasive body contouring. Design: This was an open-label, single-arm, exploratory study. Participants: Twenty adult patients presenting with subcutaneous target region adipose fat thickness greater than 2.5cm were included in this study. Measurements: Responses to a single treatment session with the ultrasound device were assessed. Change from baseline in abdominal circumference was evaluated at one, two, and three months posttreatment...
June 2018: Journal of Clinical and Aesthetic Dermatology
Bruna Souza Felix Bravo, Julien Totti, Berta Elena Alcala Gelpi, Stephanie Bianco de Souza, Leonardo Gonçalves Bravo
Generally, the shape of women's eyes are distinctly different in intercatal height from that in men. Ideally, in a woman, the lateral intercostal point is positioned above the medial intercostal point, which gives the eyes a cat-like appearance that culturally suggests youth and health. Because of aging and/or physiological changes, this area can be altered with the inversion of the lateral intercantal line lower than the medial intercantal line, producing a tired and/or sad looking appearance. Hyaluronic acid is a quick and safe method of elevating the lateral intercantal area of the eye...
June 2018: Journal of Clinical and Aesthetic Dermatology
Olabola Awosika, Misty G Eleryan, Monica Rengifo-Pardo, Lindsay Doherty, Lisa W Martin, Alison Ehrlich
Objective: International case-control studies have demonstrated that psoriasis is associated with an increased prevalence of nonalcoholic fatty liver disease (NAFLD). The purpose of the present study was to establish an association of psoriasis and NAFLD in patients attending a dermatology clinic center in the United States. Design: This was an observational, case-control study. Setting: The study setting was an outpatient dermatology clinic of the George Washington Medical Faculty Associates in Washington DC...
June 2018: Journal of Clinical and Aesthetic Dermatology
Kyle D Klingbeil, Raymond Fertig
The objective of this systematic review was to investigate the etiologies of hair loss of the eyebrow and eyelash that required hair transplantation, the optimal surgical technique, patient outcomes, and common complications. A total of 67 articles including 354 patients from 18 countries were included in this study. Most patients were women with an average age of 29 years. The most common etiology requiring hair transplantation was burns, occurring in 57.6 percent of cases. Both eyebrow and eyelash transplantation use follicular unit transplantation techniques most commonly; however, other techniques involving composite grafts and skin flaps continue to be utilized effectively with minimal complication rates...
June 2018: Journal of Clinical and Aesthetic Dermatology
Hitomi Sano, Yu Hokazono, Rei Ogawa
Objective: Pathological scars, including hypertrophic scars and keloids, have a strong predilection for specific regions of the body. Such site specificity might reflect regional differences in skin properties. Greater knowledge about the characteristics of the skin at various body regions can promote the development of clinical approaches to skin incision and flap design and reduce the formation of cutaneous scars. It could also help elucidate the etiology of pathological scar development and progression. Thus, we measured the distensibility and gross elasticity of the skin at various body sites...
June 2018: Journal of Clinical and Aesthetic Dermatology
Lee Walker, Martyn King
No abstract text is available yet for this article.
May 2018: Journal of Clinical and Aesthetic Dermatology
Betul Tas, Aysel Çağlar, Serdar Altinay
We present the case of a 15-year-old girl who presented with an unusual grouping of lesions on her upper left leg. The lesions had been present since birth. The patient had five different types of lesions: 1) transparent grouped or scattered yellowish vesicles; 2) keratotic-surfaced, grouped dark-yellowish papules; 3) bright-red grouped papules; 4) keratotic-surfaced grouped dark-red papules; and 5) patchy, punctate, and erythematous red macules. All of the lesions were intertwined along the lines of Blaschko and were in the form of irregular serpiginous plaques...
May 2018: Journal of Clinical and Aesthetic Dermatology
William A Hayward, Wilmer L Sibbitt, Randy R Sibbitt, Maheswari Muruganandam, Noelle A Rolle, Monthida Fangtham, N Suzanne Emil, Scarlett K Kettwich
Objective: Benign subcutaneous lipomas can cause musculoskeletal pain and nerve impingement. We hypothesized that the potent lipolytic and atrophic effect of 40mg/mL triamcinolone acetonide would atrophy symptomatic lipomas so surgical excision could be avoided. Design: This was a cohort study. Setting: This study took place in an ultrasound injection clinic. Participants: Eight subjects with painful symptomatic lipoma were included. Measurements: Preprocedurally, the margins of the lipomas were palpated and marked with ink, then measured in centimeters (cm)...
May 2018: Journal of Clinical and Aesthetic Dermatology
Saakshi Khattri, Orin Goldblum, Kathleen Solotkin, Yasmin Amir, Michelle S Min, Terri Ridenour, Fan Emily Yang, Mark Lebwohl
Objective: The purpose of this study was to evaluate the speed of onset of clinical response to ixekizumab (IXE) and assess the progression of visible improvement in patients with moderate-to-severe plaque psoriasis. Design: This was an interventional, randomized, open-label, Phase IIIb clinical trial. Setting: This was a single center study at the Mount Sinai School of Medicine. Participants: Twelve patients were randomized at a ratio of 1:1 to receive 80mg of ixekizumab every two (IXE Q2W) or four (IXE Q4W) weeks following a starting dose of 160mg of ixekizumab...
May 2018: Journal of Clinical and Aesthetic Dermatology
Zoe Diana Draelos, Isabelle Raymond
Objective: The goal of this study was to determine if a therapeutic cream containing PC-104 synthetic ceramides and other ingredients could help to ameliorate signs and symptoms of mild-to-moderate atopic dermatitis and other xerotic or pruritic dermatoses. Design: In this single-site, four-week study, subjects (n=50) were instructed to apply the study product three times daily to all affected areas, including a target site for evaluation and photography at baseline, Week 2, and Week 4 visits. Setting: This study took place in the private practice of the senior author...
May 2018: Journal of Clinical and Aesthetic Dermatology
Jerry Bagel, Elise Nelson
Objective: The goal of this study was to evaluate efficacy and safety of desoximetasone spray 0.25%, a topical corticosteroid, in the management of scalp and body psoriasis. Design: This was an open-label, observational study. Participants: Twenty adults aged 18 years or older with chronic scalp psoriasis present on at least 30 percent of the scalp surface area and an Investigator Global Assessment (IGA) scale score of scalp disease of at least 2 on a scale of 0 to 4 were included in the study. Measurements: Study spray was applied twice daily for four weeks, followed by 12 weeks of twice-daily application for two consecutive days weekly...
May 2018: Journal of Clinical and Aesthetic Dermatology
Hayaat F Almaary, Ramakrishnan Karthik, Cynthia Scott
Dimleplasty is the surgical creation of dimples. The demand for dimpleplasty has increased over the past few years. Despite this increasing demand, the most widely used reference point for determining where to place a surgically created dimple, the Khoo Boo Chai (KBC) point, dates back more than 60 years. The aim of our study was to assess the facial shape of a sample of men and women, all of whom had natural dimples, to determine if characteristic patterns in dimple size, location, and shape existed according to each specific facial shapes...
May 2018: Journal of Clinical and Aesthetic Dermatology
Guneet Awal, Simplepreet Kaur
Background: Various treatment modalities have been described in the literature for treating warts, but none thus far have demonstrated optimal results. Recently, the mumps, measles, and rubella (MMR) antigen has gained popularity because of its proven efficacy in the treatment of warts. Aim: The goal was to evaluate the efficacy and safety of intralesional MMR antigen in the treatment of cutaneous warts. Methods: Patients were divided into an MMR (study) group and a normal saline (control) group. Injections were administered into the single largest wart on each patient every two weeks...
May 2018: Journal of Clinical and Aesthetic Dermatology
Martyn King
No abstract text is available yet for this article.
April 2018: Journal of Clinical and Aesthetic Dermatology
Joseph F Sobanko, Kimberly Shao, Rebecca L Pearl, Sancy Leachman
The United States Preventive Services Task Force (USPSTF) 2016 recommendation for skin cancer screening in asymptomatic healthy adults concluded that current evidence is "insufficient to assess the balance and harms of visual skin examination." One contributing factor leading to the insufficient grade was a concern for cosmetic harms resulting from unnecessary biopsies or excisions. This commentary briefly highlights the pertinent studies and currently accepted methods for pigmented lesion biopsy...
April 2018: Journal of Clinical and Aesthetic Dermatology
Hamzah Mustak, Michael Rafaelof, Robert Alan Goldberg, Daniel Rootman
Background: Lid margin asymmetry and its associated compensatory mechanisms might cause patients to seek treatment to improve aesthetics. Surgery might not be indicated and can potentially worsen the asymmetry in these cases. Methods: A case series of three patients was organized to illustrate the use of botulinum toxin administered to the pre-tarsal orbicularis for the correction of micro-ptosis and improved symmetry. The marginal reflex distance and tarsal platform show were measured on both sides. Measurements were made using ImageJ software on standardized frontal photographs taken pre- and post-injection...
April 2018: Journal of Clinical and Aesthetic Dermatology
Ajay J Deshpande
Background: Acne vulgaris is a self-limiting, chronic inflammatory disorder of the pilosebaceous unit characterized by exacerbations and remissions. It is often the early manifestation of puberty, and in girls it appears relatively early. In women, acne tends to become aggravated during the menstrual period, pregnancy, and in those who are on progesterone. Acne treatment is divided into two parts: topical and systemic. For Grades 1 and 2 acne, topical treatment is sufficient, while for Grades 3 and 4 acne, systemic drugs such as tetracyclines and retinoids are required to control the symptoms...
April 2018: Journal of Clinical and Aesthetic Dermatology
Lauren C Cook, Courtney Hanna, Galen T Foulke, Elizabeth V Seiverling
Background: Dermoscopy is well established as a tool to improve the detection of cancerous skin growths. Published data suggest that dermoscopy might be useful in evaluating inflammatory dermatoses and in distinguishing between rashes and skin cancer. Objective: The authors sought to review the published literature regarding use of dermoscopy in the evaluation of inflammatory skin conditions. Methods: Using a systematic approach, the authors performed a literature search using the names of 146 inflammatory dermatoses and pairing each one separately with the search terms dermoscopy, dermatoscopy, and epiluminescence microscopy...
April 2018: Journal of Clinical and Aesthetic Dermatology
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