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Arthritis Care & Research

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https://www.readbyqxmd.com/read/29316386/changes-in-pain-sensitization-after-bariatric-surgery
#1
Joshua J Stefanik, David T Felson, Caroline M Apovian, Jingbo Niu, M Margaret Clancy, Michael P LaValley, Tuhina Neogi
OBJECTIVE: To evaluate changes in pain (at the knee and elsewhere) and pain sensitization in obese persons with knee pain undergoing bariatric surgery compared with similarly obese persons undergoing medical management. METHODS: Individuals undergoing bariatric surgery and medical management were recruited. Knee pain severity of the more painful knee (index knee) was assessed at baseline and 12 months using the WOMAC. Pressure pain threshold (PPT) was assessed at the index patella and the right wrist...
January 5, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29316383/effectiveness-of-a-web-based-personalized-rheumatoid-arthritis-risk-tool-with-or-without-a-health-educator-for-knowledge-of-ra-risk-factors
#2
Maria G Prado, Maura D Iversen, Zhi Yu, Rachel Miller Kroouze, Nellie A Triedman, Sarah S Kalia, Bing Lu, Robert C Green, Elizabeth W Karlson, Jeffrey A Sparks
OBJECTIVE: To assess knowledge of rheumatoid arthritis (RA) risk factors among unaffected first-degree relatives (FDRs) and to study whether a personalized RA education tool increases risk factor knowledge. METHODS: We performed a randomized controlled trial assessing RA educational interventions among 238 FDRs. The web-based Personalized Risk Estimator for RA (PRE-RA) tool displayed personalized RA risk results (genetics, autoantibodies, demographics, and behaviors) and educated about risk factors...
January 5, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29316377/medical-care-costs-associated-with-rheumatoid-arthritis-in-the-us-a-systematic-literature-review-and-meta-analysis
#3
Andrew Hresko, Jay Lin, Daniel H Solomon
BACKGROUND: Rheumatoid arthritis (RA) is a morbid, mortal and costly condition without a cure. Treatments for RA have expanded over the last two decades and direct medical costs may differ by types of treatments. There has not been a systematic literature review since the introduction of new RA treatments, including biologic disease modifying anti-rheumatic drugs (bDMARDs). METHODS: We conducted a systematic literature review with meta-analysis of direct medical costs associated with RA cared for in the US since the marketing of the first bDMARD...
January 5, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29316368/rash-fever-and-pulmonary-hypertension-in-a-6-year-old-female
#4
David Buchbinder, Gina A Montealegre Sanchez, Raphaela Goldbach-Mansky, Hermine Brunner, Andrew I Shulman
A previously healthy 2-year-old Guatemalan female with an undiagnosed chronic illness characterized by fever and rash had presented with anorexia, weight loss, periorbital edema, abdominal pain and distention. A chest radiograph documented cardiomegaly. An echocardiogram demonstrated a pericardial effusion, dilated right atrium, right ventricle, and main pulmonary artery as well as diminished right ventricular systolic function and pulmonary hypertension. Right ventricular systolic pressure was estimated at 90 mmHg...
January 5, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29316366/impact-of-radiation-therapy-on-scleroderma-and-cancer-outcomes-in-scleroderma-patients-with-breast-cancer
#5
Dhaval J Shah, Ram Hirpara, Corrie L Poelman, Adrianne Woods, Laura K Hummers, Fredrick M Wigley, Jean L Wright, Arti Parekh, Virginia D Steen, Robyn T Domsic, Ami A Shah
OBJECTIVES: We examined SSc patients with breast cancer to 1) identify the prevalence of radiation complications and 2) examine SSc outcomes in SSc patients who received radiation therapy (RT) as part of their cancer treatment. METHODS: Patients with SSc and breast cancer were identified from the Johns Hopkins and University of Pittsburgh Scleroderma Center databases. We examined whether erythema, blistering, ulceration, or thickening of the skin developed in the RT port...
January 5, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29316357/cerebrovascular-events-in-systemic-lupus-erythematosus
#6
John G Hanly, Qiuju Li, Li Su, Murray B Urowitz, Caroline Gordon, Sang-Cheol Bae, Juanita Romero-Diaz, Jorge Sanchez-Guerrero, Sasha Bernatsky, Ann E Clarke, Daniel J Wallace, David A Isenberg, Anisur Rahman, Joan T Merrill, Paul Fortin, Dafna D Gladman, Ian N Bruce, Michelle Petri, Ellen M Ginzler, M A Dooley, Kristjan Steinsson, Rosalind Ramsey-Goldman, Asad A Zoma, Susan Manzi, Ola Nived, Andreas Jonsen, Munther A Khamashta, Graciela S Alarcón, Winn Chatham, Ronald F van Vollenhoven, Cynthia Aranow, Meggan Mackay, Guillermo Ruiz-Irastorza, Manuel Ramos-Casals, S Sam Lim, Murat Inanc, Kenneth C Kalunian, Soren Jacobsen, Christine A Peschken, Diane L Kamen, Anca Askanase, Chris Theriault, Vernon Farewell
OBJECTIVE: To determine the frequency, associations and outcomes of cerebrovascular events (CerVEs) in a multi-ethnic/racial, prospective, SLE disease inception cohort. METHODS: Patients were assessed annually for 19 neuropsychiatric (NP) events including 5 types of CerVEs: (i) Stroke; (ii) Transient ischemia; (iii) Chronic multifocal ischemia; (iv) Subarachnoid/intracranial hemorrhage; (v) Sinus thrombosis. Global disease activity (SLEDAI-2K), SLICC/ACR damage index (SDI) and SF-36 scores were collected...
January 5, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29316341/benefits-and-sustainability-of-a-learning-collaborative-for-implementation-of-treat-to-target-in-rheumatoid-arthritis-results-of-the-traction-trial-phase-ii
#7
Daniel H Solomon, Bing Lu, Zhi Yu, Cassandra Corrigan, Leslie R Harrold, Josef S Smolen, Liana Fraenkel, Jeffrey N Katz, Elena Losina
BACKGROUND: We conducted a two-phase randomized controlled trial of a Learning Collaborative (LC) to facilitate implementation of treat to target (TTT) to manage rheumatoid arthritis (RA). We found substantial improvement in implementation of TTT in Phase I. Herein, we report on a second 9 months (Phase II) where we examined maintenance of response in Phase I and predictors of greater improvement in TTT adherence. METHODS: We recruited 11 rheumatology sites and randomized them to either receive the LC during Phase I or to a wait-list control group that received the LC intervention during Phase II...
January 5, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29316334/geriatric-assessment-of-physical-and-cognitive-functioning-in-a-diverse-cohort-of-systemic-lupus-erythematosus-patients-a-pilot-study
#8
Laura Plantinga, Benjamin D Tift, Charmayne Dunlop-Thomas, S Sam Lim, C Barrett Bowling, Cristina Drenkard
OBJECTIVE: To use multi-domain functional assessment, commonly performed in geriatric patients but novel among SLE patients, to better understand functional impairment in SLE. METHODS: We recruited 60 adult participants [aged 20-39 (26.7%), 40-59 (50.0%), and ≥60 (23.3%); 80.0% black; 90.0% female] from an existing cohort of SLE patients. During in-person visits (10/16-4/17), we evaluated physical performance (range 0-4; higher scores = better performance); cognitive performance (five fluid cognition domains; adjusted t-scores); and self-reported measures including physical functioning (t-scores), activities of daily living (ADLs), falls, and life-space mobility...
January 5, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29287314/the-symptomatic-course-of-foot-osteoarthritis-phenotypes-an-18-month-prospective-analysis-of-community-dwelling-older-adults
#9
Thomas J Downes, Linda Chesterton, Rebecca Whittle, Edward Roddy, Hylton B Menz, Michelle Marshall, Martin J Thomas
OBJECTIVE: Osteoarthritis (OA) is a heterogeneous disease with symptom progression at the foot unclear. This study investigated the symptomatic course of three pre-defined foot OA phenotypes over an 18-month period. METHODS: The Clinical Assessment Study of the Foot (CASF) is a community-based cohort of adults aged ≥50 years in North Staffordshire, UK. Participants who reported foot pain in a postal health survey and underwent radiographic assessment were mailed an 18-month follow-up survey...
December 29, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29287313/multi-center-delphi-exercise-reveals-important-key-items-for-classifying-systemic-lupus-erythematosus
#10
Gabriela Schmajuk, Bimba F Hoyer, Martin Aringer, Sindhu R Johnson, David I Daikh, Thomas Dörner
BACKGROUND: The European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR) embarked on a project to re-evaluate classification criteria for systemic lupus erythematosus (SLE). The first phase of the classification project involved generation of a broad set of items potentially useful for classification of SLE and their selection for use in a subsequent forced-choice decision analysis. METHODS: A large international group of expert lupus clinicians was invited to participate in a 2-step process to generate, rate and select items based on their importance in diagnosing early and established SLE, respectively, via a web-based survey...
December 29, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29287309/aspirin-dose-in-kawasaki-disease-the-ongoing-battle
#11
Anita Dhanrajani, Mercedes Chan, Stephanie Pau, Janet Ellsworth, Ross Petty, Jaime Guzman
BACKGROUND: Kawasaki disease (KD) is an acute childhood vasculitis that may result in coronary aneurysms. Treatment of Kawasaki disease (KD) with a single infusion of 2g/kg intravenous immunoglobulin (IVIG) is well established, but acetyl-salicylic acid (ASA) dose remains controversial. METHODS: We reviewed charts of patients with KD from two Canadian centres to assess the impact of ASA dose on IVIG resistance (operationally defined as administration of a second dose of IVIG)...
December 29, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29266882/large-vessel-dilatation-in-giant-cell-arteritis-a-different-subset-of-disease
#12
Francesco Muratore, Tanaz A Kermani, Cynthia S Crowson, Matthew J Koster, Eric L Matteson, Carlo Salvarani, Kenneth J Warrington
OBJECTIVE: To compare patients with large-vessel GCA (LV-GCA) characterized by wall thickening, stenosis and/or occlusion of subclavian arteries to those with subclavian dilatation. METHODS: For the purposes of the present retrospective study, two different subsets of LV-GCA were identified and compared from an established cohort of patients with radiographic evidence of subclavian artery vasculitis secondary to GCA: 1.LV-GCA with wall thickening, stenosis and/or occlusion of subclavian arteries (Group 1) 2...
December 20, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29266862/orthopedic-surgery-among-patients-with-rheumatoid-arthritis-a-population-based-study-to-identify-risk-factors-sex-differences-and-time-trends
#13
Michael Richter, Cynthia S Crowson, Eric L Matteson, Ashima Makol
OBJECTIVE: To identify risk factors for large joint (LJS) versus small joint surgery (SJS) in rheumatoid arthritis (RA) and evaluate trends in surgery rates over time. METHODS: A retrospective medical record review was performed of all orthopedic surgeries following first fulfillment of 1987 ACR criteria for adult-onset RA among residents of Olmsted County, Minnesota, USA in 1980-2013. Risk factors were examined using Cox models adjusted for age, sex and calendar year of RA incidence...
December 20, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29266857/-like-no-one-is-listening-to-me-a-qualitative-study-of-patient-provider-discordance-between-global-assessments-of-disease-activity-in-rheumatoid-arthritis
#14
Zoran Kvrgic, Gladys B Asiedu, Cynthia S Crowson, Jennifer L Ridgeway, John M Davis
OBJECTIVE: The objective of this study was to explore the perspectives and experiences of patients with rheumatoid arthritis (RA) whose assessments of their disease differ from those of their rheumatology care provider. METHODS: A total of 20 adult RA patients with patient-provider discordance at their most recent rheumatology appointment (within 4 weeks) were recruited. Discordance was defined by an absolute difference of 25 or more between patient and provider global assessments on visual analog scales (VASs) of disease activity...
December 20, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29266813/is-acpa-positive-ra-still-a-more-severe-disease-than-acpa-negative-ra-a-longitudinal-cohort-study-in-ra-patients-diagnosed-from-2000-onwards
#15
Aleid C Boer, Annelies Boonen, Annette H M van der Helm van Mil
OBJECTIVE: Anti-citrullinated-protein antibodies (ACPA)-positive rheumatoid arthritis (RA) is considered as more severe than ACPA-negative RA, because of its association with joint destruction. Clinically relevant joint destruction is now infrequent, thanks to adequate disease suppression. According to patients, important outcomes are pain, fatigue and independence. We evaluated if ACPA-positive RA-patients diagnosed ≥2000 have more severe self-reported limitations and impairments including restrictions at work than ACPA-negative RA-patients...
December 20, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29245188/the-unmet-needs-of-aboriginal-australians-with-musculoskeletal-pain-a-mixed-method-systematic-review
#16
Ivan B Lin, Samantha Bunzli, Donna B Mak, Charmaine Green, Roger Goucke, Juli Coffin, Peter B O'Sullivan
OBJECTIVE: Musculoskeletal pain (MSP) conditions are the biggest cause of disability and internationally, Indigenous peoples experience a higher burden. There are conflicting reports about Aboriginal Australians and MSP. We conducted a systematic review to describe the prevalence, associated factors, impacts, care access, health care experiences, and factors associated with MSP among Aboriginal Australians. METHODS: A systematic search of quantitative and qualitative scientific and grey literature (PROSPERO number: CRD42016038342)...
December 15, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29245187/news-on-relapsing-polychondritis-the-patients-experience
#17
EDITORIAL
Jean-Charles Piette, Jérémie Dion, Nathalie Costedoat-Chalumeau
In this issue of Arthritis Care & Research, the authors of Patient-Perception of Disease-Related Symptoms and Complications in Relapsing Polychondritis report for the first time the patient's view over the disease (1). Thanks go to them for this important step forward. The method used however, carries some limitations, as indicated very honestly by the authors. This article is protected by copyright. All rights reserved.
December 15, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29245186/endothelial-dysfunction-in-early-systemic-lupus-erythematosus-patients-and-controls-without-previous-cardiovascular-events
#18
Mara Taraborelli, Edoardo Sciatti, Ivano Bonadei, Vincenzo Terlizzi, Micaela Fredi, Roberta Zani, Giovanni Cancarini, Angela Tincani, Franco Franceschini, Enrico Vizzardi, Ilaria Cavazzana
OBJECTIVES: To assess the prevalence and risk factors for endothelial dysfunction detected by peripheral artery tonometry in systemic lupus erythematosus patients with early disease without cardiovascular disease and risk factors. METHODS: All the consecutive adult lupus patients, with a disease duration less than 5 years, seen in our Hospital from December 2014 to March 2016 were considered. We excluded patients with any history of cardiovascular disease or risk factors possibly affecting peripheral artery tonometry...
December 15, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29245180/factors-influencing-cane-use-for-the-management-of-knee-osteoarthritis-a-cross-sectional-survey
#19
Julia Hart, Rana S Hinman, Ans Van Ginckel, Michelle Hall, Rachel Nelligan, Kim L Bennell
OBJECTIVE: To investigate demographic, symptom-related and cognitive determinants of cane use for knee osteoarthritis (OA) and prioritise the factors that could facilitate cane use in people with no previous cane use. METHODS: A survey of people aged ≥45 years with a clinical diagnosis of knee OA was conducted. The survey included two sections: i) demographic and cognitive determinants of cane use assessed via subscales of the Cane Cognitive Mediator Scale; ii) 19 statements, underpinned by the Behaviour Change Wheel theoretical framework, relating to factors that could facilitate regular cane use...
December 15, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29245175/development-and-testing-of-a-hybrid-measure-of-muscle-strength-in-juvenile-dermatomyositis-for-use-in-routine-care
#20
Giulia Camilla Varnier, Silvia Rosina, Cristina Ferrari, Angela Pistorio, Alessandro Consolaro, Francesca Bovis, Sara Dalprà, Clarissa Pilkington, Susan Maillard, Adele Civino, Elena Tsitsami, Jaime de Inocencio, Marija Jelusic, Jelena Vojinovic, Graciela Espada, Balahan Makay, Maria Martha Katsicas, Polixeni Pratsidou-Gertsi, Dragana Lazarevic, Anand Prahalad Rao, Denise Pires Marafon, Nicolino Ruperto, Alberto Martini, Angelo Ravelli
OBJECTIVE: To develop and test a hybrid measure of muscle strength for juvenile dermatomyositis (JDM), which is based on the combination of the Manual Muscle Testing 8 (MMT8) and the Childhood Myositis Assessment Scale (CMAS), but is more comprehensive than the former and more feasible than the latter. METHODS: The hybrid MMT/CMAS (hMC) is composed of all 8 items of the MMT8 and 3 items of the CMAS: 1) time of head lift; 2) assessment of abdominal muscles; 3) floor rise...
December 15, 2017: Arthritis Care & Research
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