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Neurodegenerative Disease Management

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https://www.readbyqxmd.com/read/27879155/managing-cognition-in-progressive-supranuclear-palsy
#1
Timothy Rittman, Ian Ts Coyle-Gilchrist, James B Rowe
Cognitive impairment is integral to the syndrome of progressive supranuclear palsy. It is most commonly described as a frontal dysexecutive syndrome but other impairments include apathy, impulsivity, visuospatial and memory functions. Cognitive dysfunction may be exacerbated by mood disturbance, medication and communication problems. In this review we advocate an individualized approach to managing cognitive impairment in progressive supranuclear palsy with the education of caregivers as a central component...
November 23, 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27855543/alcohol-related-cognitive-impairment-current-trends-and-future-perspectives
#2
Victoria Hayes, Apo Demirkol, Nicole Ridley, Adrienne Withall, Brian Draper
Excessive alcohol use is associated with a wide range of physical, psychological and social consequences, and is responsible for a significant proportion of the burden of disease globally. An area which has received increasing interest is alcohol-related brain damage, not just because of the cost to the individual and society through resource utilization, but also because of the potential for prevention and reversibility. This paper aims to review the current literature on this subject and seeks to explore issues around diagnosis and treatment of alcohol-related brain damage...
November 18, 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27855537/communication-in-dementia-care
#3
Elizabeth Chmelik, Reiko Emtman, Anna Borisovskaya, Soo Borson
Dementia is a progressive neurodegenerative illness that affects a growing number of older adults in our country. We discuss ways to improve the management of persons with dementia within current healthcare models. Specifically, we argue that structured communication at regular intervals is essential for dementia care at all phases of illness. We emphasize the need for a single healthcare provider to take on a central role in organizing communication between patient, family and other healthcare providers in the outpatient setting...
November 18, 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27855532/pain-assessment-tools-for-older-adults-with-dementia-in-long-term-care-facilities-a-systematic-review
#4
Selina Chow, Ronald Chow, Michael Lam, Leigha Rowbottom, Drew Hollenberg, Erika Friesen, Olivia Nadalini, Henry Lam, Carlo DeAngelis, Nathan Herrmann
AIM: The aim of this review is to document pain assessment tools used primarily for older adults in long-term care facilities and compare self-report and observer-rated tools. METHODS: A literature search was conducted in Ovid MEDLINE(®), Embase, Cochrane and PsycINFO. Keywords included 'dementia', 'pain management' and 'managing pain'. RESULTS: Of 1033 references, 23 articles were selected for inclusion. Six tools were self-rated and 18 tools were administered by an observer...
November 18, 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27827565/family-physicians-perspectives-on-memory-clinics-in-primary-care
#5
Linda Lee, Loretta M Hillier
AIM: To identify family physicians' perception of the primary care collaborative memory clinic (PCCMC) care model. METHODS: Physicians with access to a PCCMC completed a survey to assess their satisfaction with various aspects of PCCMC care delivery (n = 78). Interviews were conducted with a purposeful sample of physicians (n = 20) to gather their opinions on the strengths, gaps in care and benefits associated with the PCCMC model. RESULTS: There was support for this care model in providing timely quality dementia care at a primary care level, making it easier for referring physicians to manage challenging aspects of dementia care...
November 9, 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27827553/solutions-for-improving-communication-with-parkinson-s-disease-patients
#6
Thomas Holtgraves
No abstract text is available yet for this article.
November 9, 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27827552/alzheimer-s-disease-cerebrolysin-and-nanotechnology-as-a-therapeutic-strategy
#7
Hari S Sharma, Dafin F Muresanu, Aruna Sharma
No abstract text is available yet for this article.
November 9, 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27813452/cognitive-remediation-to-enhance-mobility-in-older-adults-the-crem-study
#8
Joe Verghese, Emmeline Ayers, Jeannette R Mahoney, Anne Ambrose, Cuiling Wang, Roee Holtzer
Mobility disabilities represent the most prevalent disability among seniors. Emerging evidence indicates that executive functions play an important role in maintaining mobility. However, the use of cognitive remediation programs to enhance mobility has not been investigated in a full-scale randomized control trial. The CREM study is a single-blind randomized control trial to examine the effect of computerized cognitive remediation versus computer-based health education training on mobility in 420 seniors. The primary outcome is change in gait speed during normal walking and walking-while-talking conditions from baseline to postintervention...
November 4, 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27813444/advances-in-a%C3%AE-plaque-detection-and-the-value-of-knowing-overcoming-challenges-to-improving-patient-outcomes-in-alzheimer-s-disease
#9
Aleksandar Jovalekic, Santiago Bullich, Ana Catafau, Susan de Santi
Clinical diagnosis of Alzheimer's disease (AD) can be challenging as numerous diseases mimic the characteristics of AD. In this light, recent guidelines developed by different associations and working groups point out the need for biomarkers to support AD diagnosis. This paper discusses 18F-labeled radiotracers (which are indicated for PET imaging of the brain) and ongoing clinical studies that aim to generate new evidence for the usage of amyloid imaging. In addition to their relatively long half-life, these agents are known for their high sensitivity and high negative predictive values for detection of neuritic Aβ plaques...
November 4, 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27874500/rehabilitation-in-multiple-sclerosis-the-role-of-tele-rehabilitation-gaming
#10
Mathias Mäurer
No abstract text is available yet for this article.
December 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27874499/muscle-elastography-in-multiple-sclerosis-spasticity
#11
Giovanni Illomei
Ultrasound elastography is a novel imaging modality for evaluating the elasticity of biological tissues. The technique is widely used in oncology to detect and differentiate malignant lesions in soft tissues. Studies have explored use of ultrasound elastography to measure the mechanical properties of muscle in patients with multiple sclerosis spasticity. Real-time elastography was shown to correlate well with subjective scales commonly used to measure MS spasticity. Ultrasound elastography has the potential to become a new objective gold standard to monitor symptom evolution in patients with MS spasticity and to evaluate the efficacy of antispasticity treatment...
December 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27874498/what-is-new-in-multiple-sclerosis-spasticity-research-poster-session-highlights
#12
Angelo Ghezzi
Each year at the MS Experts Summit, relevant research in the field of multiple sclerosis spasticity is featured in poster sessions. In 2016, six new studies were presented.
December 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27874497/country-breakout-session-highlights
#13
Angelo Ghezzi, Linard Filli, Claudio Solaro, Claude Mekies, Lamberto Landete, Jan Lycke
At the 2016 MS Experts Summit, country-relevant aspects pertaining to the management of symptoms and disability in multiple sclerosis (MS), with emphasis on those associated with spasticity, were explored in interactive country breakout sessions chaired by selected MS experts. Attendees had the opportunity to review and discuss topics in their own native language. After feedback from each session leader, key messages were collated and presented in a Plenary Session by Summit chair, Professor Angelo Ghezzi. Topics at this year's Summit included: gait tracking (Germany/Switzerland); the Care Alliance against MS spasticity (Italy); MS spasticity and associated symptoms (France); improvement in MS symptoms and functionality and patients' independence (Spain); Swedish MS guidelines (Sweden/Rest of World)...
December 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27874496/2016-multiple-sclerosis-experts-summit-foreword
#14
Angelo Ghezzi
No abstract text is available yet for this article.
December 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27874495/evolution-of-multiple-sclerosis-spasticity-associated-symptoms-latest-data
#15
Peter Flachenecker
In addition to muscle stiffness and increasing mobility restrictions, symptoms commonly associated with multiple sclerosis (MS) spasticity are spasms, sleep disturbances, pain, fatigue and bladder dysfunction. Treatment options include trigger factor avoidance, physiotherapy and antispasticity medication. Oral antispasticity agents commonly used in Germany are baclofen, tizanidine and gabapentin, but physician and patient satisfaction with their effectiveness is low. Over the past few years, randomized controlled trials, observational studies and registry data have demonstrated the positive risk:benefit profile of add-on 9-delta-tetra-hydrocannabinol:cannabidiol oromucosal spray for moderate-to-severe resistant MS spasticity...
December 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27874494/pediatric-multiple-sclerosis-updates-in-epidemiology-clinical-features-and-management
#16
Sona Narula
Consensus definitions for acute demyelinating syndromes in children have led to increased recognition of pediatric multiple sclerosis and improved our understanding of its pathogenesis, epidemiology and treatment. An estimated 2-10% of MS patients experience their first clinical symptom in childhood. Multiple genetic and environmental risk factors have been identified in the pathogenesis of pediatric MS, although further research to determine their interplay is required. Clinical trials of emerging disease-modifying therapies in children are nearing completion...
December 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27874493/web-based-medical-and-health-information-in-multiple-sclerosis-for-patients-and-physicians
#17
Alessandra Solari
No abstract text is available yet for this article.
December 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27874492/an-update-on-ms-nurse-professional-an-ongoing-project-of-the-european-multiple-sclerosis-platform
#18
Anne Winslow
Within the multidisciplinary team required to manage people with multiple sclerosis (MS) effectively, the nurse is the central component of coordinated care and support. A 2009 survey led by the European Multiple Sclerosis Platform, an umbrella organization of national MS associations, identified variance and disparity across Europe in the nursing care of MS patients. This led to development of MS Nurse PROfessional, a continuing medical education-accredited modular online learning program endorsed and approved by leading international nursing and professional groups, and people with MS, as a tool to support the evolving role of the European MS nurse...
December 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27874491/movement-disorders-in-multiple-sclerosis-and-their-treatment
#19
Günther Deuschl
Hyperkinetic movement disorders such as tremors are not uncommon in patients with multiple sclerosis (MS). The classical feature is intention tremor, whereas rest tremors appear not to occur. Treatment is mainly invasive, with options of Gamma Knife surgery, thalamotomy or deep brain stimulation depending on individual circumstances. Deep brain stimulation is the only option for patients who require a bilateral intervention. All treatment recommendations have only low evidence. Tremors can also be cured spontaneously by a subsequent strategic MS lesion...
December 2016: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/27874490/symptom-tracking-from-clinically-isolated-syndrome-to-advanced-multiple-sclerosis
#20
Mar Tintoré
No abstract text is available yet for this article.
December 2016: Neurodegenerative Disease Management
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