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Case Reports in Neurology

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https://www.readbyqxmd.com/read/29681829/dysphagia-causes-symptom-fluctuations-after-oral-l-dopa-treatment-in-a-patient-with-parkinson-disease
#1
Hiromasa Sato, Toshiyuki Yamamoto, Masako Sato, Yoshihiko Furusawa, Miho Murata
Objective: The causes of "delayed-on" and "no-on" phenomena in Parkinson disease (PD) are thought to have some impact on the progress of L-DOPA from the time of ingestion until it reaches the brain and is converted to dopamine. Dysphagia can cause fluctuating symptom expression in L-DOPA therapy for PD. Case Description: A 69-year-old man with PD presented with "delayed-on" and "no-on" phenomena. The patient developed a gait disorder at age 60 years, and he began coughing on his food during breakfast at age 64 years...
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29681828/emergency-foramen-magnum-decompression-for-tonsillar-herniation-secondary-to-meningoencephalitis
#2
Fardad T Afshari, Barbara Wysota, Michelle Oswal, Gordan Mazibrada, Edward A White
Tonsillar herniation and coning is a rare and often late presentation of meningoencephalitis, and is associated with poor neurological outcome. We report the case of a 16-year-old female who presented unresponsive with radiological evidence of tonsillar herniation secondary to meningoencephalitis. She underwent an emergency foramen magnum decompression and C1 laminectomy with full recovery and no residual neurological deficit.
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29681827/hemicrania-continua-associated-with-classic-scintillating-scotoma
#3
Eva Auffenberg, Friedemann Bender, Tobias Freilinger
Hemicrania continua (HC) is a rare primary headache disorder, characterized by persistent unilateral pain associated with cranial autonomic symptoms and prompt response to indomethacin. While migrainous features (including aura) have been recognized in cluster headache, there have been only single reports of HC with aura. Here, we report the case of a 53-year-old man with constant right-sided headache and superimposed exacerbations to severe pain lasting for several hours. Secondary etiologies were excluded, and a diagnosis of HC was established after prompt and complete response to treatment with indomethacin...
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29681826/frontal-phonological-agraphia-and-acalculia-with-impaired-verbal-short-term-memory-due-to-left-inferior-precentral-gyrus-lesion
#4
Yasuhisa Sakurai, Emi Furukawa, Masanori Kurihara, Izumi Sugimoto
We report a patient with phonological agraphia (selective impairment of kana [Japanese phonetic writing] nonwords) and acalculia (mental arithmetic difficulties) with impaired verbal short-term memory after a cerebral hemorrhage in the opercular part of the left precentral gyrus (Brodmann area 6) and the adjacent postcentral gyrus. The patient showed phonemic paragraphia in five-character kana nonword writing, minimal acalculia, and reduced digit and letter span. Mental arithmetic normalized after 8 months and agraphia recovered to the normal range at 1 year after onset, in parallel with an improvement of the auditory letter span score from 4 to 6 over a period of 14 months and in the digit span score from 6 to 7 over 24 months...
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29681825/arterial-spin-labeling-imaging-of-a-giant-aneurysm-leading-to-subarachnoid-hemorrhage-following-cerebral-infarction
#5
Tatsuya Ueno, Tatsuya Sasaki, Masatoshi Iwamura, Tomoya Kon, Jin-Ichi Nunomura, Hiroshi Midorikawa, Masahiko Tomiyama
An 83-year-old Japanese man was admitted with dysarthria and right hemiparesis. He had had a large intracranial aneurysm on the left internal carotid artery 5 years before admission and had been followed up under conservative treatment. On admission, diffusion-weighted imaging revealed a hyperintense signal on the left anterior choroidal artery territory. Time-of-flight magnetic resonance angiography demonstrated poor visibility of the middle and anterior cerebral arteries and the inferior giant aneurysm, suggesting distal emboli from aneurysm thrombosis or a reduction of blood outflow due to aneurysm thrombosis...
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29681824/bilateral-ageusia-and-tongue-anesthesia-following-unilateral-brainstem-infarct-a-case-report-with-a-brief-review-of-the-literature
#6
Christian Saleh, Simona Negoias, Franca Wagner, Marie-Luise Mono
We present the case of a 63-year-old male patient who suffered bilateral ageusia following a unilateral left-sided mesencephalon infarct. To the best of our knowledge, this is the first description of a mesencephalon lesion leading to ageusia. We discuss the literature on this rare but important symptom following a stroke.
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29606953/a-report-of-a-case-involving-body-lateropulsion-with-numbness-of-the-ipsilesional-fingers-caused-by-a-small-infarction-in-the-dorsal-part-of-the-middle-medulla
#7
Yumiko Yamaoka, Sadahiro Kishishita, Yohei Takayama, Seiji Okubo
Based on the complexity of functional anatomy, a small infarction in the medulla can produce various types of clinical symptoms or signs depending on the location of this infarction. We describe the case of a 46-year-old man who presented with sudden onset of body lateropulsion to the left side and numbness of the ipsilateral fingers. 3-tesla diffusion-weighted magnetic resonance imaging with a section thickness of 2 mm revealed a small infarction in the dorsal part of the left middle medulla. To our knowledge, this is the first case report describing vestibular dysfunction apparent upon otoelectrophysiological examination but without vestibular symptoms or signs except for body lateropulsion...
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29606952/cervical-intramedullary-schwannoma-case-report-and-review-of-the-literature
#8
José Omar Navarro Fernández, Alejandro Monroy Sosa, Bernardo Cacho Díaz, Víctor Andrés Arrieta, Ramses Uriel Ortíz Leyva, Ana María Cano Valdez, Gervith Reyes Soto
Cervical intramedullary schwannomas are extraordinarily rare. Gross total resection is the best therapeutic option for these types of tumors. Although rare, intramedullary schwannomas should be considered as a differential diagnosis of intramedullary lesions since a good prognosis can be guaranteed to the majority of these patients. We present a case of a cervical intramedullary schwannoma surgically treated in a 19-year-old male patient who initially presented with motor neuron disease.
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29515424/intracranial-leptomeningeal-carcinomatosis-a-diagnostic-study-with-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography
#9
Susanna Nuvoli, Silvia Contu, Bi Llie Joy Pung, Patrizia Solinas, Giuseppe Madeddu, Angela Spanu
Leptomeningeal carcinomatosis (LC) diagnosis is based on cerebrospinal fluid (CSF) cytological analysis and contrast-enhanced magnetic resonance imaging (MRI); however, low sensitivity was evidenced in some cases delaying prompt and adequate treatments. Brain 18 F-fluorodeoxyglucose positron emission tomography (18 F-FDG PET) was also employed in doubtful cases. We retrospectively described 4 suspected LC cases with uncertain or undetectable MRI and initially negative CSF cytology. Whole-body (WB) and brain 18 F-FDG PET/computed tomography (CT) were used, the latter showing intracranial tracer uptakes suspected for LC in 3/4 cases...
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29515423/clinical-and-genetic-analysis-of-an-asian-indian-family-with-charcot-marie-tooth-disease-type-4c
#10
Raji P Grewal, Kinsi Oberoi, Leema Reddy Peddareddygari
Charcot-Marie-Tooth disease type 4C, an autosomal recessive genetic neuropathy, is caused by mutations in the SH3TC2 (SH3 domain and tetratricopeptide repeats 2) gene. Interestingly, although mutations in this gene have been observed in European gypsies, a population that originated in India, there are few publications describing Indian patients. We report our analysis of a 50-year-old woman of Asian Indian descent with onset of progressive distal weakness and sensory loss in childhood. A clinical examination revealed the presence of a neuropathy with pes cavus without spinal abnormalities...
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29515422/convulsive-seizures-as-presenting-symptom-of-metronidazole-induced-encephalopathy-a-case-report
#11
Caspar Godthaab Sørensen, William Kristian Karlsson, Faisal Mohammad Amin, Mette Lindelof
Introduction: Encephalopathy and convulsive seizures are rare manifestations of metronidazole toxicity. The incidence is unknown, but the condition has most frequently been reported in patients in their fifth to sixth decades. Usually, this condition is regarded as reversible, but permanent deficits and even death have been reported. Case Report: A 66-year-old female patient undergoing metronidazole treatment for pleural empyema was admitted to our institution after her second episode of seizure...
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29515421/central-variant-posterior-reversible-encephalopathy-syndrome-with-albuminocytologic-dissociation
#12
Sang-Woo Lee, Seung-Jae Lee
Posterior reversible encephalopathy syndrome (PRES) is a disorder of reversible vasogenic brain edema which mainly involves the parieto-occipital lobes in various clinical settings. The main mechanism is known to be cerebral autoregulation failure and endothelial dysfunction leading to the disruption of the blood-brain barrier. We report the case of a 47-year-old woman with PRES which involved the brain stem and thalami, sparing the cerebral hemispheres. She was admitted to the emergency room because of acute-onset confusion...
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29515420/elderly-onset-neuromyelitis-optica-spectrum-disorder-with-pre-existing-prednisone-allergy
#13
Christopher Hollen, Omer Suhaib, Aaron Farrow, Evgeny Sidorov
We present a case of an 82-year-old man with new-onset neuromyelitis optica (NMO) spectrum disorder, the treatment of which was complicated by a severe pre-existing prednisone allergy. His age caused much initial doubt about his diagnosis, and his corticosteroid allergy altered our management as we attempted to minimize risk to the patient. Our patient was a healthy 82-year-old, right-handed man who presented with sensory loss of the bilateral lower extremities and progressive, painless vision loss. MRI showed bilateral pre-chiasmatic optic nerve and optic chiasm enhancement, along with enhancement within the thoracic spinal cord from T3 to T7...
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29515419/infliximab-associated-chronic-inflammatory-central-nervous-system-disease-and-peroneal-nerve-injury-in-a-psoriatic-patient-refractory-to-treatment-case-report-with-10-year-follow-up
#14
Sandra C Signore, Birka Brauns, Gunther Schütze, Christoph P Dohm, Mathias Bähr, Rotraut Mössner, Pawel Kermer
The tumor necrosis factor-α (TNF-α) antagonists infliximab, adalimumab, and etanercept have been approved for the treatment of chronic inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, psoriasis, and psoriatic arthritis. Manifestations of demyelinating disease have been reported for patients receiving TNF-α antagonists. We describe a rare manifestation of a chronic inflammatory process affecting both the central and peripheral nervous system in a patient who received infliximab for the treatment of psoriasis and psoriatic arthritis...
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29515418/a-case-of-traumatic-brain-injury-presenting-with-musical-hallucinations
#15
Yasutaka Kobayashi
A 67-year-old woman was hospitalized for rehabilitation from the after effects of a traumatic brain injury. In addition to memory impairment, attention disorder, and executive dysfunction, she experienced musical hallucinations. Brain magnetic resonance imaging revealed cerebral contusion in the bilateral temporal lobes and the left frontal lobe. Case reports of musical hallucinations caused by traumatic brain injury are extremely rare.
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29515417/microsurgical-treatment-of-intraventricular-cavernoma-with-prior-planning-neuroendoscopy
#16
Flavio Nigri, Jucilana Dos Santos Viana, Pedro Henrique da Costa Ferreira Pinto, Elington Lannes Simões, Carlos Roberto Telles Ribeiro
Microsurgery remains the gold standard treatment for intraventricular lesions, but it is not without limitations. The cerebral ventricles approach is considered a challenge for neurosurgeons because of their deep location and their intimate association with critical areas of the brain. It has been shown that direct endoscopic view is superior to magnetic resonance imaging (MRI) in identifying intraventricular structures and lesions. Also, during neuroendoscopy, there is no cerebrospinal fluid leak causing brain collapse as seen in microsurgery...
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29515427/lateral-medullary-ischemic-infarct-caused-by-posterior-inferior-cerebellar-artery-aneurysm
#17
Muhammad Taimur Malik, Edgar J Kenton Iii, Dana Vanino, Shamsher S Dalal, Ramin Zand
Posterior inferior cerebellar artery (PICA) aneurysms are rare. The most common complication of intracranial aneurysms is rupture causing subarachnoid hemorrhage. Ischemic infarct, although more common in giant thrombosed aneurysms, is a very rare manifestation of small intracranial aneurysms. Here we describe a patient who presented with lateral medullary acute infarction associated with an ipsilateral, small (4 × 3.5 mm), unruptured and non-thrombosed PICA aneurysm.
September 2017: Case Reports in Neurology
https://www.readbyqxmd.com/read/29515426/a-rare-case-of-glossopharyngeal-neuralgia-due-to-neurovascular-conflict
#18
Marc Vecchi, Ricardo Pereira Mestre, S Luciamma Thiekalamuriyil, Roberto Cartolari
In the context of painful cranial neuropathies, a very rare cause is represented by the irritation of the glossopharyngeal nerve due to various aetiologic factors. Here, we present a case of neuralgia of the ninth right cranial nerve due to a compression of its nerve root upon the kinking of the homolateral vertebral artery, resulting in a disabling clinical overview for the patient. Our objective was to focus the reader's attention on the clinical manifestation, which alone could lead to an immediate diagnosis...
September 2017: Case Reports in Neurology
https://www.readbyqxmd.com/read/29515425/dystonic-seizures-and-intense-hyperperfusion-of-the-basal-ganglia-in-a-patient-with-anti-n-methyl-d-aspartate-receptor-encephalitis
#19
Hideyuki Matsumoto, Hideji Hashida, Yukitoshi Takahashi
This report describes a rare case presenting with dystonic seizures due to anti-N-methyl-D-aspartate (NMDA) receptor encephalitis. The patient was an 18-year-old woman with repeated right-dominant dystonic seizures even under sedation. Single-photon emission computed tomography (SPECT) showed intense hyperperfusion of the caudate nuclei, putamen, globus pallidus, thalamus, and insula on the left side, suggesting encephalitis. Antibodies against NMDA receptors were detected in the sera and cerebrospinal fluids...
September 2017: Case Reports in Neurology
https://www.readbyqxmd.com/read/29422854/reversible-cerebral-vasoconstriction-syndrome-due-to-atovaquone
#20
Takahiro Makino, Ikuo Kamitsukasa, Shoichi Ito
A 72-year-old Japanese woman with rheumatoid arthritis whose activity decreased with previous treatments had recurrent thunderclap headaches during an atovaquone regimen for the treatment of pneumocystis pneumonia. The recurrent headaches disappeared after discontinuation of the drug. Brain magnetic resonance images showed multiple cerebral vasoconstrictions of cerebral arteries with vasogenic cerebral white matter edema, which diminished several weeks later. We diagnosed the patient's headaches as reversible cerebral vasoconstriction syndrome due to atovaquone...
September 2017: Case Reports in Neurology
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