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Cardiology Research and Practice

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https://www.readbyqxmd.com/read/29201489/factors-affecting-health-related-quality-of-life-in-hospitalized-patients-with-heart-failure
#1
Georgia Audi, Aggeliki Korologou, Ioannis Koutelekos, Georgios Vasilopoulos, Kostas Karakostas, Kleanthi Makrygianaki, Maria Polikandrioti
This study identified factors affecting health related quality of life (HRQOL) in 300 hospitalized patients with heart failure (HF). Data were collected by the completion of a questionnaire which included patients' characteristics and the Minnesota Living with Heart Failure Questionnaire (MLHFQ). Analysis of data showed that the median of the total score of MLHFQ was 46 and the median of the physical and mental state was 22 and 6, respectively. Also, participants who were householders or had "other" professions had lower score of 17 points and therefore better quality of life compared to patients who were civil/private employees (p < 0...
2017: Cardiology Research and Practice
https://www.readbyqxmd.com/read/29170719/subclinical-hypothyroidism-and-its-association-with-increased-cardiovascular-mortality
#2
REVIEW
Alvaro Altamirano Ufion, Beenish Zulfiqar, Abdalla Hassan, Roshanak Habibi, Prajwal Boddu
Thyroid hormones play an important role in regulating different metabolism functions and multiple organs' performance. Changes in the thyroid hormone axis can lead to profound effects on the stability of vital organs and systems, especially the cardiovascular system. Hypothyroidism is classified according to the clinical presentation as overt and subclinical. There is some evidence supporting the benefits of thyroxine hormone replacement for subclinical hypothyroidism on cardiovascular mortality outcomes. However, the clinical relevance of measuring and treating high thyroid-stimulating hormone (TSH) levels in newly diagnosed heart failure patients with preserved ejection fraction requires further study...
2017: Cardiology Research and Practice
https://www.readbyqxmd.com/read/29158941/corrigendum-to-falls-and-fractures-in-the-elderly-with-sinus-node-disease-the-impact-of-pacemaker-implantation
#3
Nazmi Krasniqi, Diana Segalada, Thomas F Lüscher, Kurt Lippuner, Laurent Haegeli, Jan Steffel, Thomas Wolber, Corinna Brunckhorst, Johannes Holzmeister, David Hürlimann, Firat Duru
[This corrects the article DOI: 10.1155/2012/498102.].
2017: Cardiology Research and Practice
https://www.readbyqxmd.com/read/29130017/clinical-characteristics-management-and-outcomes-of-suspected-poststroke-acute-coronary-syndrome
#4
Sylvia Marie Biso, Marvin Lu, Toni Anne De Venecia, Supakanya Wongrakpanich, Mary Rodriguez-Ziccardi, Sujani Yadlapati, Marina Kishlyansky, Harish Seetha Rammohan, Vincent M Figueredo
Background: Acute coronary syndrome (ACS) can complicate acute ischemic stroke, causing significant morbidity and mortality. To date, literatures that describe poststroke acute coronary syndrome and its morbidity and mortality burden are lacking. Methods: This is a single center, retrospective study where clinical characteristics, cardiac evaluation, and management of patients with suspected poststroke ACS were compared and analyzed for their association with inpatient mortality and 1-year all-cause mortality...
2017: Cardiology Research and Practice
https://www.readbyqxmd.com/read/29062582/effect-of-remote-ischemic-preconditioning-on-perioperative-cardiac-events-in-patients-undergoing-elective-percutaneous-coronary-intervention-a-meta-analysis-of-16-randomized-trials
#5
REVIEW
Xiangming Wang, Na Kong, Chuanwei Zhou, Deeraj Mungun, Zakaria Iyan, Yan Guo, Zhijian Yang
BACKGROUND: The main objective of this meta-analysis was to investigate whether remote ischemic preconditioning (RIPC) reduces cardiac and renal events in patients undergoing elective cardiovascular interventions. METHODS AND RESULTS: We systematically searched articles published from 2006 to 2016 in PubMed, EMBASE, Web of Science, Cochrane Library, and Google Scholar. Odds ratios (ORs) with 95% confidence intervals (CIs) were used as the effect index for dichotomous variables...
2017: Cardiology Research and Practice
https://www.readbyqxmd.com/read/28811952/divorce-and-severity-of-coronary-artery-disease-a-multicenter-study
#6
Amin Daoulah, Mushabab Al-Murayeh, Salem Al-Kaabi, Amir Lotfi, Osama E Elkhateeb, Salem M Al-Faifi, Saleh Alqahtani, James Stewart, Jon Heavey, William T Hurley, Mohamed N Alama, Mazen Faden, Mohamed Al-Shehri, Ali Youssef, Alawi A Alsheikh-Ali
The association between marital status and coronary artery disease (CAD) is supported by numerous epidemiological studies. While divorce may have an adverse effect on cardiac outcomes, the relationship between divorce and severe CAD is unclear. We conducted a multicenter, observational study of consecutive patients undergoing coronary angiography during the period between April 1, 2013, and March 30, 2014. Of 1,068 patients, 124 (12%) were divorced. Divorce was more frequent among women (27%) compared to men (6%)...
2017: Cardiology Research and Practice
https://www.readbyqxmd.com/read/28785506/comparison-of-the-effects-of-carperitide-and-tolvaptan-on-patients-with-left-ventricular-dysfunction-a-two-center-retrospective-study
#7
Chikahiko Koeda, Shohei Yamaya, Maiko Hozawa, Masayuki Sato, Kazuhiro Nasu, Tomohiro Takahashi, Katsutoshi Terui
In patients with left ventricular (LV) dysfunction, diuretics can reduce blood pressure and lead to electrolyte abnormalities. The aim of this study was to compare the effects of tolvaptan (T group) and carperitide (C group) in these patients. Sixty-one consecutive patients admitted to the Iwate Prefectural Kuji Hospital or the Emergency Center of the Iwate Medical University between July 2011 and April 2015 were included in this study. These patients had acute heart failure (HF) and were initially treated with furosemide...
2017: Cardiology Research and Practice
https://www.readbyqxmd.com/read/28512592/the-relationship-between-body-mass-index-and-the-severity-of-coronary-artery-disease-in-patients-referred-for-coronary-angiography
#8
Anne B Gregory, Kendra K Lester, Deborah M Gregory, Laurie K Twells, William K Midodzi, Neil J Pearce
Background and Aim. Obesity is associated with an increased risk of cardiovascular disease and may be associated with more severe coronary artery disease (CAD); however, the relationship between body mass index [BMI (kg/m(2))] and CAD severity is uncertain and debatable. The aim of this study was to examine the relationship between BMI and angiographic severity of CAD. Methods. Duke Jeopardy Score (DJS), a prognostic tool predictive of 1-year mortality in CAD, was assigned to angiographic data of patients ≥18 years of age (N = 8,079)...
2017: Cardiology Research and Practice
https://www.readbyqxmd.com/read/28465858/the-prevalence-and-awareness-of-cardiovascular-diseases-risk-factors-among-the-lebanese-population-a-prospective-study-comparing-urban-to-rural-populations
#9
Iqbal Fahs, Zainab Khalife, Diana Malaeb, Mohammad Iskandarani, Pascale Salameh
Introduction. CVDs are largely driven by modifiable risk factors. This study sought to determine the awareness and prevalence of the modifiable CVDs risk factors among the Lebanese population. Methods. In a cross-sectional survey, 1000 participants aged ≥ 45 years were randomly selected from pharmacies and interviewed. The data was analyzed with SPSS version 21.0 software. Results. Differences between urban and rural areas include alcohol consumption (2.8% versus 1.7%; p = 0.0001), cardioprotective vegetable servings (6...
2017: Cardiology Research and Practice
https://www.readbyqxmd.com/read/28421156/the-personalization-of-clopidogrel-antiplatelet-therapy-the-role-of-integrative-pharmacogenetics-and-pharmacometabolomics
#10
REVIEW
Arwa M Amin, Lim Sheau Chin, Dzul Azri Mohamed Noor, Muhamad Ali Sk Abdul Kader, Yuen Kah Hay, Baharudin Ibrahim
Dual antiplatelet therapy of aspirin and clopidogrel is pivotal for patients undergoing percutaneous coronary intervention. However, the variable platelets reactivity response to clopidogrel may lead to outcome failure and recurrence of cardiovascular events. Although many genetic and nongenetic factors are known, great portion of clopidogrel variable platelets reactivity remain unexplained which challenges the personalization of clopidogrel therapy. Current methods for clopidogrel personalization include CYP2C19 genotyping, pharmacokinetics, and platelets function testing...
2017: Cardiology Research and Practice
https://www.readbyqxmd.com/read/28348916/aerobic-training-intensity-for-improved-endothelial-function-in-heart-failure-patients-a-systematic-review-and-meta-analysis
#11
M J Pearson, N A Smart
Objective. Flow-mediated dilation (FMD) is widely utilised to assess endothelial function and aerobic exercise improves FMD in heart failure patients. The aim of this meta-analysis is to quantify the effect of aerobic training intensity on FMD in patients with heart failure. Background. A large number of studies now exist that examine endothelial function in patients with heart failure. We sought to add to the current literature by quantifying the effect of the aerobic training intensity on endothelial function...
2017: Cardiology Research and Practice
https://www.readbyqxmd.com/read/28246571/avoiding-the-learning-curve-for-transcatheter-aortic-valve-replacement
#12
Sergey Gurevich, Ranjit John, Rosemary F Kelly, Ganesh Raveendran, Gregory Helmer, Demetris Yannopoulos, Timinder Biring, Brett Oestreich, Santiago Garcia
Objectives. To evaluate whether collaboration between existing and new transcatheter aortic valve replacement (TAVR) programs could help reduce the number of cases needed to achieve optimal efficiency. Background. There is a well-documented learning curve for achieving procedural efficiency and safety in TAVR procedures. Methods. A multidisciplinary collaboration was established between the Minneapolis VA Medical Center (new program) and the University of Minnesota (established program since 2012, n = 219) 1 year prior to launching the new program...
2017: Cardiology Research and Practice
https://www.readbyqxmd.com/read/27974990/pediatric-heart-failure-lagging-and-sagging-of-care-in-low-income-settings-a-hospital-based-review-of-cases-in-ethiopia
#13
Solmon Gebremariam, Tamirat Moges
Introduction. Causes of acute heart failure in children range from simple myocarditis complicating chest infection to complex structural heart diseases. Objective. To describe patterns, predictors of mortality, and management outcomes of acute heart failure in children. Methods. In retrospective review, between February 2012 and October 2015 at a tertiary center, 106 admitted cases were selected consecutively from discharge records. Data were extracted from patients chart and analyzed using SPSS software package...
2016: Cardiology Research and Practice
https://www.readbyqxmd.com/read/27965912/impact-of-lifestyle-intervention-on-hdl-induced-enos-activation-and-cholesterol-efflux-capacity-in-obese-adolescent
#14
Jenny Wesnigk, Luc Bruyndonckx, Vicky Y Hoymans, Ann De Guchtenaere, Tina Fischer, Gerhard Schuler, Christiaan J Vrints, Volker Adams
Background. Endothelial dysfunction occurs in obese children and adolescent and is regarded as a key step in the development of atherosclerosis. Important components for the development of endothelial dysfunction are reduced activity of endothelial nitric oxide synthase (eNOS) and an increase in cholesterol deposition in the vessel wall, due to reduced reverse cholesterol transport (RCT) activity. High density lipoprotein (HDL) exhibits antiatherosclerotic properties including modulation of eNOS activity and cholesterol efflux capacity...
2016: Cardiology Research and Practice
https://www.readbyqxmd.com/read/27885351/coronary-angiography-safety-between-transradial-and-transfemoral-access
#15
Santosh Kumar Sinha, Vikas Mishra, Nasar Afdaali, Mukesh Jitendra Jha, Ashutosh Kumar, Mohammad Asif, Ramesh Thakur, Chandra Mohan Varma
Background and Aim. The aim of study was to evaluate safety, feasibility, and procedural variables of transradial approach compared with transfemoral approach in a standard population of patients undergoing coronary catheterization as one of the major criticisms of the transradial approach is that it takes longer overall procedure and fluoroscopy time, thereby causing more radiation exposure. Method. Between January 2015 and December 2015, a total of 1,997 patients in LPS Institute of Cardiology, GSVM Medical College, Kanpur, UP, India, undergoing coronary catheterization were randomly assigned to the transradial or transfemoral approach...
2016: Cardiology Research and Practice
https://www.readbyqxmd.com/read/27882261/prevalence-of-hepatitis-c-virus-seropositivity-and-its-impact-on-coronary-artery-disease-among-egyptian-patients-referred-for-coronary-angiography
#16
Ragab Abd El Salam, Baher Nabil, Marawan Saber, Hany A AbdelWahab, Tamer Saber
Background. We tested the prevalence and impact of HCV seropositivity among Egyptian patients referred for coronary angiography. Subjects and Methods. This cross-sectional study was conducted in Zagazig University hospitals including 509 patients scheduled for elective coronary angiography between June 2013 and June 2014. By taking full history on admission, laboratory workup including HCV Ab, echocardiography study, and coronary angiography, we calculated the mean number of coronary artery lesions and the mean number of affected coronary artery vessels for all patients...
2016: Cardiology Research and Practice
https://www.readbyqxmd.com/read/27872790/kansas-city-cardiomyopathy-questionnaire-utility-in-prediction-of-30-day-readmission-rate-in-patients-with-chronic-heart-failure
#17
Shengchuan Dai, Manoucher Manoucheri, Junhong Gui, Xiang Zhu, Divyanshu Malhotra, Shenjing Li, Jason D'souza, Fnu Virkram, Aditya Chada, Haibing Jiang
Background. Heart failure (HF) is one of the most common diagnoses associated with hospital readmission. We designed this prospective study to evaluate whether Kansas City Cardiomyopathy Questionnaire (KCCQ) score is associated with 30-day readmission in patients hospitalized with decompensated HF. Methods and Results. We enrolled 240 patients who met the study criteria. Forty-eight (20%) patients were readmitted for decompensated HF within thirty days of hospital discharge, and 192 (80%) patients were not readmitted...
2016: Cardiology Research and Practice
https://www.readbyqxmd.com/read/27668118/impact-of-body-mass-index-on-short-term-outcomes-in-patients-undergoing-percutaneous-coronary-intervention-in-newfoundland-and-labrador-canada
#18
Anne B Gregory, Kendra K Lester, Deborah M Gregory, Laurie K Twells, William K Midodzi, Neil J Pearce
Background and Aim. Obesity (BMI ≥ 30 kg/m(2)) is associated with advanced cardiovascular disease requiring procedures such as percutaneous coronary intervention (PCI). Studies report better outcomes in obese patients having these procedures but results are conflicting or inconsistent. Newfoundland and Labrador (NL) has the highest rate of obesity in Canada. The aim of the study was to examine the relationship between BMI and vascular and nonvascular complications in patients undergoing PCI in NL. Methods...
2016: Cardiology Research and Practice
https://www.readbyqxmd.com/read/27597926/association-between-stable-coronary-artery-disease-and-in-vivo-thrombin-generation
#19
Benjamin Valente-Acosta, Manuel Alfonso Baños-González, Marco Antonio Peña-Duque, Marco Antonio Martínez-Ríos, Leslie Quintanar-Trejo, Gad Aptilon-Duque, Mirthala Flores-García, David Cruz-Robles, Guillermo Cardoso-Saldaña, Aurora de la Peña-Díaz
Background. Thrombin has been implicated as a key molecule in atherosclerotic progression. Clinical evidence shows that thrombin generation is enhanced in atherosclerosis, but its role as a risk factor for coronary atherosclerotic burden has not been proven in coronary artery disease (CAD) stable patients. Objectives. To evaluate the association between TAT levels and homocysteine levels and the presence of coronary artery disease diagnosed by coronary angiography in patients with stable CAD. Methods and Results...
2016: Cardiology Research and Practice
https://www.readbyqxmd.com/read/27563480/impact-of-rosuvastatin-treatment-on-hdl-induced-pkc-%C3%AE-ii-and-enos-phosphorylation-in-endothelial-cells-and-its-relation-to-flow-mediated-dilatation-in-patients-with-chronic-heart-failure
#20
Ephraim B Winzer, Pauline Gaida, Robert Höllriegel, Tina Fischer, Axel Linke, Gerhard Schuler, Volker Adams, Sandra Erbs
Background. Endothelial function is impaired in chronic heart failure (CHF). Statins upregulate endothelial NO synthase (eNOS) and improve endothelial function. Recent studies demonstrated that HDL stimulates NO production due to eNOS phosphorylation at Ser(1177), dephosphorylation at Thr(495), and diminished phosphorylation of PKC-βII at Ser(660). The aim of this study was to elucidate the impact of rosuvastatin on HDL mediated eNOS and PKC-βII phosphorylation and its relation to endothelial function. Methods...
2016: Cardiology Research and Practice
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