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International Journal of Endocrinology

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https://www.readbyqxmd.com/read/28912811/corrigendum-to-in-vitro-antioxidant-treatment-of-semen-samples-in-assisted-reproductive-technology-effects-of-myo-inositol-on-nemaspermic-parameters
#1
Mariangela Palmieri, Palma Papale, Antonietta Della Ragione, Giuseppa Quaranta, Giovanni Russo, Sabatino Russo
[This corrects the article DOI: 10.1155/2016/2839041.].
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28912810/latent-inflammation-and-insulin-resistance-in-adipose-tissue
#2
REVIEW
I S Stafeev, A V Vorotnikov, E I Ratner, M Y Menshikov, Ye V Parfyonova
Obesity is a growing problem in modern society and medicine. It closely associates with metabolic disorders such as type 2 diabetes mellitus (T2DM) and hepatic and cardiovascular diseases such as nonalcoholic fatty liver disease, atherosclerosis, myocarditis, and hypertension. Obesity is often associated with latent inflammation; however, the link between inflammation, obesity, T2DM, and cardiovascular diseases is still poorly understood. Insulin resistance is the earliest feature of metabolic disorders. It mostly develops as a result of dysregulated insulin signaling in insulin-sensitive cells, as compared to inactivating mutations in insulin receptor or signaling proteins that occur relatively rare...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28912809/the-biphasic-effect-of-vitamin-d-on-the-musculoskeletal-and-cardiovascular-system
#3
REVIEW
Armin Zittermann
This narrative review summarizes beneficial and harmful vitamin D effects on the musculoskeletal and cardiovascular system. Special attention is paid to the dose-response relationship of vitamin D with clinical outcomes. In infants and adults, the risk of musculoskeletal diseases is highest at circulating 25-hydroxyvitamin D (25OHD) concentrations below 25 nmol/L and is low if 40-60 nmol/L are achieved. However, evidence is also accumulating that in elderly people the risk of falls and fractures increases again at circulating 25OHD levels > 100 nmol/L...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28912808/association-of-polymorphisms-in-toll-like-receptors-4-and-9-with-autoimmune-thyroid-disease-in-korean-pediatric-patients
#4
Won Kyoung Cho, Jung-Pil Jang, Eun-Jeong Choi, Moonbae Ahn, Shin Hee Kim, Kyoung Soon Cho, So Hyun Park, In Cheol Baek, Min Ho Jung, Tai-Gyu Kim, Byung-Kyu Suh
BACKGROUND: Toll-like receptors (TLRs) have been suggested to be associated with the development of AITD. METHODS: Fifteen single-nucleotide polymorphisms in 7 TLR genes were analyzed in 104 Korean children (girls = 86, boys = 18) with AITD (Hashimoto disease (HD) = 44, Graves' disease (GD) = 60, thyroid-associated ophthalmopathy (TAO) = 29, and non-TAO = 31) with 183 controls. RESULTS: GD showed higher frequencies of the TLR4 rs1927911 C allele than control...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28883832/bmi-modulates-the-effect-of-thyroid-hormone-on-lipid-profile-in-euthyroid-adults
#5
Yanqiu Wang, Qinglei Yin, Min Xu, Qicheng Ni, Weiqing Wang, Qidi Wang
The impacts of thyroid hormones (TH) on lipid profile in euthyroid adults have gained much attention. It is currently unknown whether BMI influences such interaction. In the present study, we investigate the role of BMI in modulating the association between TH and lipid parameters in 1372 euthyroid healthy adults. Our results show that thyroid parameters are differentially associated with lipid profile. FT3 is positively correlated with total cholesterol (β = 0.176 ± 0.046, P < 0.001) and LDL cholesterol levels (β = 0...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28852407/the-association-between-bone-quality-and-atherosclerosis-results-from-two-large-population-based-studies
#6
V Lange, M Dörr, U Schminke, H Völzke, M Nauck, H Wallaschofski, A Hannemann
OBJECTIVE: It is highly debated whether associations between osteoporosis and atherosclerosis are independent of cardiovascular risk factors. We aimed to explore the associations between quantitative ultrasound (QUS) parameters at the heel with the carotid artery intima-media thickness (IMT), the presence of carotid artery plaques, and the ankle-brachial index (ABI). METHODS: The study population comprised 5680 men and women aged 20-93 years from two population-based cohort studies: Study of Health in Pomerania (SHIP) and SHIP-Trend...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28852406/regulation-of-corticosteroidogenic-genes-by-micrornas
#7
Stacy Robertson, Louise A Diver, Samantha Alvarez-Madrazo, Craig Livie, Ayesha Ejaz, Robert Fraser, John M Connell, Scott M MacKenzie, Eleanor Davies
The loss of normal regulation of corticosteroid secretion is important in the development of cardiovascular disease. We previously showed that microRNAs regulate the terminal stages of corticosteroid biosynthesis. Here, we assess microRNA regulation across the whole corticosteroid pathway. Knockdown of microRNA using Dicer1 siRNA in H295R adrenocortical cells increased levels of CYP11A1, CYP21A1, and CYP17A1 mRNA and the secretion of cortisol, corticosterone, 11-deoxycorticosterone, 18-hydroxycorticosterone, and aldosterone...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28848603/baseline-demographic-and-clinical-characteristics-of-patients-with-adrenal-incidentaloma-from-a-single-center-in-china-a-survey
#8
Lele Li, Guoqing Yang, Ling Zhao, Jingtao Dou, Weijun Gu, Zhaohui Lv, Juming Lu, Yiming Mu
AIM: To investigate the clinical and endocrinological characteristics of patients with adrenal incidentaloma (AI). MATERIALS AND METHODS: This retrospective study enrolled 1941 AI patients hospitalized at the Department of Endocrinology, Chinese PLA General Hospital, Beijing, China, between January 1997 and December 2016. The patient gender, age at visits, imaging features, functional status, and histological results were analyzed. RESULTS: Of the 1941 patients, 984 (50...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28845158/2d-shear-wave-elastography-in-the-evaluation-of-parathyroid-lesions-in-patients-with-hyperparathyroidism
#9
Ioana Golu, Ioan Sporea, Lavinia Moleriu, Anca Tudor, Marioara Cornianu, Adrian Vlad, Romulus Timar, Melania Balas, Daniela Amzar, Mihaela Vlad
BACKGROUND AND AIMS: 2D-shear wave elastography (2D-SWE) is a relatively new elastographic technique. The aim of the present study is to determine the values of the elasticity indexes (EI) measured by 2D-SWE in parathyroid benign lesions (adenomas or hyperplasia) and to establish if this investigation is helpful for the preoperative identification of the parathyroid adenoma. MATERIAL AND METHODS: The study groups were represented by 22 patients with primary or tertiary hyperparathyroidism, diagnosed by specific tests, and 43 healthy controls, in whom the thyroid parenchyma was evaluated, in order to compare the EI of the thyroid tissue with those of the parathyroid lesions...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28845157/thickness-of-extraocular-muscle-and-orbital-fat-in-mri-predicts-response-to-glucocorticoid-therapy-in-graves-ophthalmopathy
#10
Lingling Xu, Linna Li, Cuihua Xie, Meiping Guan, Yaoming Xue
33 patients with active, moderate-severe Graves' ophthalmopathy (GO) received 4.5 g methylprednisolone for 12 weeks and were divided by efficacy into two groups (responsive and unresponsive). All patients and 10 controls underwent orbital MRI examination at baseline. No significant difference was seen in baseline clinical characteristics between the two GO groups. The values of exophthalmos were higher in both GO groups than in the control and were higher in the responsive group versus the unresponsive group...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28839453/variants-of-interleukin-22-gene-confer-predisposition-to-autoimmune-thyroid-disease
#11
Rong-Hua Song, Qian Li, Wen Wang, Qiu-Ming Yao, Xiao-Qing Shao, Jin-An Zhang
As there are no previous studies on the interleukin-22 (IL-22) variants in autoimmune thyroid disease (AITD), the present study aimed to explore the association between polymorphisms of IL-22 and the predisposition to AITD. The study had 975 AITD patients, including 639 Graves' disease (GD) and 336 Hashimoto's thyroiditis (HT) individuals and 851 healthy cohorts. Ligase detection reaction (LDR) and direct sequencing method were used for genotyping the IL-22 gene polymorphisms at rs2046068, rs2227478, rs2227485, rs11611206, and rs1179251...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28819359/screening-for-cushing-syndrome-at-the-primary-care-level-what-every-general-practitioner-must-know
#12
REVIEW
Ernest Yorke, Yacoba Atiase, Josephine Akpalu, Osei Sarfo-Kantanka
Cushing's syndrome is a rare entity, and a high index of suspicion is needed for screening in a primary care setting. The clinical awareness of the primary care physician (PCP) to the highly indicative signs and symptoms such as facial plethora, proximal myopathy, reddish purple striae, and easy bruisability should alert him to look for biochemical evidence of Cushing's syndrome through any of the first-line screening tests, namely, 24-hour urinary free cortisol, overnight dexamethasone suppression test, or late-night salivary cortisol...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28808444/association-of-sudoscan-values-with-vibration-perception-threshold-in-chinese-patients-with-type-2-diabetes-mellitus
#13
Xiaoming Zhu, Fei Mao, Siying Liu, Hangping Zheng, Bin Lu, Yiming Li
AIMS/INTRODUCTION: SUDOSCAN has been proved to be an efficient method in detecting diabetic microvascular complications. In this study, we determine to detect the possible relationship between vibration perception threshold (VPT) and cardiac autonomic neuropathy (CAN) values produced by SUDOSCAN. MATERIALS AND METHODS: A total of 920 Chinese patients with T2DM were enrolled in the study. Spearman correlation analysis and multivariate regression analysis were performed to determine the relation between CAN and VPT values...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28808443/angiotensin-converting-enzyme-inhibition-and-parathyroid-hormone-secretion
#14
Sarah Zaheer, Jenifer M Brown, Molly Connors, Jonathan S Williams, Gail K Adler, Anand Vaidya
BACKGROUND: Prior studies suggest that renin-angiotensin-aldosterone system (RAAS) inhibitors decrease parathyroid hormone (PTH) secretion. OBJECTIVE: To evaluate the effect of angiotensin-converting enzyme inhibitors (ACEi) on serum PTH in participants with and without primary hyperparathyroidism (P-HPT). METHODS: An open-label, single-arm, pilot study whereby participants with and without P-HPT had PTH were evaluated before and after 1 week of maximally tolerated lisinopril therapy...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28791047/central-precocious-puberty-and-response-to-gnrha-therapy-in-children-with-cerebral-palsy-and-moderate-to-severe-motor-impairment-data-from-a-longitudinal-case-control-multicentre-italian-study
#15
Patrizia Bruzzi, Maria Francesca Messina, Alessandra Bartoli, Barbara Predieri, Laura Lucaccioni, Simona Filomena Madeo, Alberto Verrotti, Filippo De Luca, Lorenzo Iughetti
BACKGROUND: Children affected by neurodevelopmental disability could experience early pubertal changes at least 20 times more than the general population. Limited data about central precocious puberty (CPP) among children affected by cerebral palsy (CP) are available. METHODS: This is a longitudinal, observational, retrospective, case-control study involving 22 children affected by CPP and CP (group A), 22 paired with CP but without CPP (group B), and 22 children with CPP without CP...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28791046/corrigendum-to-fracture-risk-in-type-2-diabetes-current-perspectives-and-gender-differences
#16
Giuseppina T Russo, Annalisa Giandalia, Elisabetta L Romeo, Nunziata Morabito, Marco Muscianisi, Maria Concetta Ruffo, Antonino Catalano, Domenico Cucinotta
[This corrects the article DOI: 10.1155/2016/1615735.].
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28781594/plasma-lncrna-gas8-as1-as-a-potential-biomarker-of-papillary-thyroid-carcinoma-in-chinese-patients
#17
Dongxue Zhang, Xin Liu, Bojun Wei, Guoliang Qiao, Tao Jiang, Zhenwen Chen
BACKGROUND: Long noncoding RNAs (lncRNAs) were recently shown to have potential in the diagnosis and prognosis for numerous cancers. lncRNA GAS8-AS1 is decreased in papillary thyroid cancer (PTC) tissue, but its plasma expression and clinical value in patients with PTC remain unknown. MATERIALS AND METHODS: We investigated the expression profile of plasma GAS8-AS1 in 97 patients with PTC and 39 patients with nodular goiter by quantitative real-time polymerase chain reaction...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28761442/effects-of-exercise-training-on-fat-loss-and-lean-mass-gain-in-mexican-american-and-korean-premenopausal-women
#18
Shenghui Wu, Kyung-Shin Park, Joseph B McCormick
We investigated the effect of exercise training on body composition change in women. Nineteen Mexican-American and 18 Korean premenopausal overweight/obese women were randomized into one of the following groups: control, low-intensity training group (LI), and high-intensity training group (HI). Subjects completed 12 weeks of training at 50-56% maximal oxygen consumption (LI) or 65-70% maximal oxygen consumption (HI). Body composition components were measured at baseline and after training using dual-energy X-ray absorptiometry for Mexican-Americans, while whole-body composition was measured by the direct segmental multifrequency bioelectrical impedance analysis and abdominal fat was measured by single-slice computed tomography for Koreans...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28751911/corrigendum-to-male-osteoporosis-in-the-elderly
#19
Patrizia D'Amelio, Giovanni Carlo Isaia
[This corrects the article DOI: 10.1155/2015/907689.].
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28751910/corrigendum-to-the-alliance-of-mesenchymal-stem-cells-bone-and-diabetes
#20
Nicola Napoli, Rocky Strollo, Angela Paladini, Silvia I Briganti, Paolo Pozzilli, Sol Epstein
[This corrects the article DOI: 10.1155/2014/690783.].
2017: International Journal of Endocrinology
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