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PLoS Currents

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https://www.readbyqxmd.com/read/28439448/spatial-determinants-of-ebola-virus-disease-risk-for-the-west-african-epidemic
#1
Kate Zinszer, Kathryn Morrison, Aman Verma, John S Brownstein
INTRODUCTION: Although many studies have investigated the probability of Ebola virus disease (EVD) outbreaks while other studies have simulated the size and speed of EVD outbreaks, few have investigated the environmental and population-level predictors of Ebola transmission once an outbreak is underway. Identifying strong predictors of transmission could help guide and target limited public health resources during an EVD outbreak. We examined several environmental and population-level demographic predictors of EVD risk from the West African epidemic...
March 31, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28439447/the-development-of-a-veterans-health-administration-emergency-management-research-agenda
#2
Aram Dobalian, Maria Claver, Deborah Riopelle, Tamar Wyte-Lake, Ismelda Canelo
INTRODUCTION: The Veterans Health Administration (VHA), the largest integrated healthcare delivery system in the United States, is charged with ensuring timely access to high-quality care for veterans during disasters, and supporting national, state, local, and tribal emergency management and homeland security efforts. In 2008, the VHA Office of Public Health (OPH) sponsored the first VHA Emergency Management Research Agenda-setting conference to develop research priorities that address the needs of veterans and to position VHA as a national leader in emergency management by having VHA serve as a "laboratory" for the development of evidence-based emergency management practices...
March 23, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28357154/vaccine-hesitancy-in-search-of-the-risk-communication-comfort-zone
#3
Joshua Greenberg, Eve Dubé, Michelle Driedger
INTRODUCTION: This paper reports the findings of a national online survey to parents of children aged 5 and younger. The objectives of the study were to assess parental understanding of childhood immunizations, identify sources of information that they trust for vaccine-related content, assess where parents with young children stand on the key issues in the public debate about vaccination, and identify which risk communication messages are most effective for influencing the behaviours of vaccine hesitant parents...
March 3, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28357153/the-demand-for-disaster-microinsurance-for-small-businesses-in-urban-slums-the-results-of-surveys-in-three-indian-cities
#4
Ronak Patel, Garrett Walker, Mihir Bhatt, Vishal Pathak
BACKGROUND: Small informal businesses make up the core markets for many poor urban communities, providing essential goods, services, and livelihoods. Many of these communities and businesses exist in hazardous locations. In most cases, these business owners do not have access to proper coping mechanisms including risk transfer and lack resilience to shocks. Access to risk-transfer in the form of insurance for these small businesses is extremely limited. This demand survey is the first phase of an intervention to test disaster microinsurance for these businesses...
March 1, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28367356/correction-contributing-and-terminating-factors-of-a-large-rsv-outbreak-in-an-adult-hematology-and-transplant-unit
#5
(no author information available yet)
[This corrects the article DOI: 10.1371/currents.outbreaks.3bc85b2a508d205ecc4a5534ecb1f9be.].
February 27, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28357155/analytical-and-clinical-validity-study-of-firststepdx-plus-a-chromosomal-microarray-optimized-for-patients-with-neurodevelopmental-conditions
#6
Charles Hensel, Rena Vanzo, Megan Martin, Sean Dixon, Christophe Lambert, Brynn Levy, Lesa Nelson, Andy Peiffer, Karen S Ho, Patricia Rushton, Moises Serrano, Sarah South, Kenneth Ward, Edward Wassman
INTRODUCTION: Chromosomal microarray analysis (CMA) is recognized as the first-tier test in the genetic evaluation of children with developmental delays, intellectual disabilities, congenital anomalies and autism spectrum disorders of unknown etiology. ARRAY DESIGN: To optimize detection of clinically relevant copy number variants associated with these conditions, we designed a whole-genome microarray, FirstStep(Dx) PLUS (FSDX). A set of 88,435 custom probes was added to the Affymetrix CytoScanHD platform targeting genomic regions strongly associated with these conditions...
February 27, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28386515/current-state-and-problems-of-radiation-risk-communication-based-on-the-results-of-a-2012-whole-village-survey
#7
Yujiro Kuroda
PURPOSE: The entire village of Iitate was contaminated by radioactive material from the Fukushima Daiichi Nuclear Power Plant; even today, the residents remain evacuated. For the villagers, risk communication is an important element of recovery and maintaining health. This analysis focuses on the problem of radiation, presents results from a questionnaire of villagers, and examines methods for future risk communication activities. SUBJECTS AND METHODS: In May 2012, anonymous surveys were sent to 2914 heads of households whose addresses were registered in Iitate...
February 24, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28357156/does-zika-virus-cause-microcephaly-applying-the-bradford-hill-viewpoints
#8
Asma Awadh, Abrar Ahmad Chughtai, Amalie Dyda, Mohamud Sheikh, David J Heslop, Chandini Raina MacIntyre
INTRODUCTION: Zika virus has been documented since 1952, but been associated with mild, self-limiting disease. Zika virus is classified as an arbovirus from a family of Flaviviridae and primarily spread by Aedes Aegypti mosquitos. However, in a large outbreak in Brazil in 2015, Zika virus has been associated with microcephaly. METHODS: In this review we applied the Bradford-Hill viewpoints  to investigate the association between Zika virus and microcephaly. We examined historical studies, available data and also compared historical rates of microcephaly prior to the Zika virus outbreak...
February 22, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28286700/women-s-challenges-and-capabilities-in-disasters-a-case-report-of-the-twin-earthquakes-of-eastern-azerbaijan-iran
#9
Sanaz Sohrabizadeh, Katayoun Jahangiri, Reza Khani Jazani, Javad Babaie, Mohammad Javad Moradian, Behnaz Rastegarfar
Introduction: The twin earthquakes of eastern Azerbaijan induced considerable devastations of many villages and cities. About 70% of all victims were women and children. The present case report was aimed at describing the lessons learnt from both capabilities and challenges of girls and women after the twin earthquakes of eastern Azerbaijan. Methods: A qualitative approach using in-depth unstructured interviews was used for this study. A total of 13 participants (two men and 11 women), affected by the quakes, were interviewed applying the purposeful sampling method...
February 22, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28286701/first-report-of-the-east-central-south-african-genotype-of-chikungunya-virus-in-rio-de-janeiro-brazil
#10
Thiara Manuele Alves Souza, Elzinandes Leal Azeredo, Jessica Badolato-Corrêa, Paulo Vieira Damasco, Carla Santos, Fabienne Petitinga-Paiva, Priscila Conrado Guerra Nunes, Luciana Santos Barbosa, Márcio Costa Cipitelli, Thais Chouin-Carneiro, Nieli Rodrigues Costa Faria, Rita Maria Ribeiro Nogueira, Fernanda de Bruycker-Nogueira, Flavia Barreto Dos Santos
BACKGROUND: Chikungunya virus (CHIKV) is an arbovirus that causes an acute febrile syndrome with a severe and debilitating arthralgia. In Brazil, the Asian and East-Central South African (ECSA) genotypes are circulating in the north and northeast of the country, respectively. In 2015, the first autochthonous cases in Rio de Janeiro, Brazil were reported but until now the circulating strains have not been characterized. Therefore, we aimed here to perform the molecular characterization and phylogenetic analysis of CHIKV strains circulating in the 2016 outbreak occurred in the municipality of Rio de Janeiro...
February 14, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28255518/correction-coordinating-the-provision-of-health-services-in-humanitarian-crises-a-systematic-review-of-suggested-models
#11
(no author information available yet)
[This corrects the article DOI: 10.1371/currents.dis.95e78d5a93bbf99fca68be64826575fa.].
February 10, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28275525/correction-focused-training-for-humanitarian-responders-in-regional-anesthesia-techniques-for-a-planned-randomized-controlled-trial-in-a-disaster-setting
#12
(no author information available yet)
[This corrects the article DOI: 10.1371/currents.dis.e75f9f9d977ac8adededb381e3948a04.].
February 6, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28255519/health-consequences-of-typhoon-haiyan-in-the-eastern-visayas-region-using-a-syndromic-surveillance-database
#13
Miguel Antonio Salazar, Ronald Law, Arturo Pesigan, Volker Winkler
INTRODUCTION: Typhoon Haiyan was the strongest storm recorded in Philippine history. Surveillance in Post Extreme Emergencies and Disasters (SPEED) was activated during the typhoon response. This study analyzes the health impact of different diseases during different timeframes post-disaster during Typhoon Haiyan in 2013 using a syndromic surveillance database. METHODS: SPEED reports medical consultations based on 21 syndromes covering a range of conditions from three syndrome groups: communicable diseases, injuries, and non-communicable diseases (NCDs)...
February 6, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28286699/rural-women-s-experience-of-living-and-giving-birth-in-relief-camps-in-pakistan
#14
Humaira Maheen, Elizabeth Hoban
BACKGROUND: Women are more vulnerable than men in the same natural disaster setting. Preexisting gender inequality, socio-cultural community dynamics and poverty puts women at significant risk of mortality. Pregnant women are particularly vulnerable because of their limited or no access to prenatal and obstetric care during any disaster or humanitarian emergency setting. METHODS: In-depth interviews were conducted with 15 women who gave birth during the 2011 floods in Sindh Province, Pakistan...
January 31, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28286698/-i-aedes-aegypti-i-control-through-modernized-integrated-vector-management
#15
Laith Yakob, Sebastian Funk, Anton Camacho, Oliver Brady, W John Edmunds
INTRODUCTION: In the context of the ongoing, unprecedented Zika virus outbreak in the Americas, the World Health Organization has expressed its support for developing and up-scaling three novel approaches to controlling the Aedes aegypti mosquito: the Sterile Insect Technique (SIT), the Release of Insects carrying Dominant Lethal genes (RIDL) and the release of Wolbachia-infected mosquitoes. Whereas the former two approaches are temporary insect population suppression strategies, Wolbachia infection is a self-sustaining, invasive strategy that uses inherited endosymbiotic bacteria to render natural mosquito populations arbovirus resistant...
January 30, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28239513/rapid-molecular-detection-of-zika-virus-in-acute-phase-urine-samples-using-the-recombinase-polymerase-amplification-assay
#16
Ahmed Abd El Wahed, Sabri Saeed Sanabani, Oumar Faye, Rodrigo Pessôa, João Veras Patriota, Ricardo Rodrigues Giorgi, Pranav Patel, Susanne Böhlken-Fascher, Olfert Landt, Matthias Niedrig, Paolo Marinho de Andrade Zanotto, Claus Peter Czerny, Amadou A Sall, Manfred Weidmann
BACKGROUND: Currently the detection of Zika virus (ZIKV) in patient samples is done by real-time RT-PCR. Samples collected from rural area are sent to highly equipped laboratories for screening. A rapid point-of-care test is needed to detect the virus, especially at low resource settings. METHODOLOGY/PRINCIPAL FINDINGS: In this report, we describe the development of a reverse transcription isothermal recombinase polymerase amplification (RT-RPA) assay for the identification of ZIKV...
January 25, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28228974/the-solidarity-and-health-neutrality-of-physicians-in-war-peace
#17
Frederick M Burkle, Timothy Erickson, Johan von Schreeb, Stephanie Kayden, Anthony Redmond, Emily Yy Chan, Francesco Della Corte, Hilarie Cranmer, Yasuhiro Otomo, Kirsten Johnson, Nobhojit Roy
The wars in the Middle East have led to unprecedented threats and attacks on patients, healthcare workers, and purposeful targeting of hospitals and medical facilities. It is crucial that every healthcare provider, both civilian and military, on either side of the conflict become aware of the unique and inherent protections afforded to them under International Humanitarian Law. However, these protections come with obligations. Whereas Governments must guarantee these protections, when violated, medical providers have equal duty and obligations under the Law to ensure that they will neither commit nor assist in these violations nor take part in any act of hostility...
January 20, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28228976/facebook-enables-disaster-research-studies-the-use-of-social-media-to-recruit-participants-in-a-post-disaster-setting
#18
Karin Hugelius, Annsofie Adolfsson, Mervyn Gifford, Per Örtenwall
INTRODUCTION: Disaster research entails several methodological challenges, given the context of a disaster. This article aims to describe and evaluate the use of Facebook as a tool to recruit participants for a self-selected Internet sample using a web-based survey in a post-disaster setting in the Philippines after the Haiyan typhoon hit parts of the country in November 2013. METHOD: An invitation to a web-based survey about health was posted on several Facebook pages during a ten-day period...
January 19, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28228973/duchenne-regulatory-science-consortium-meeting-on-disease-progression-modeling-for-duchenne-muscular-dystrophy
#19
Jane Larkindale, Richard Abresch, Enrique Aviles, Abby Bronson, Janice Chin, Pat Furlong, Heather Gordish-Dressman, Elizabeth Habeeb-Louks, Erik Henricson, Hans Kroger, Charles Lynn, Stephen Lynn, Dana Martin, Glen Nuckolls, William Rooney, Klaus Romero, Lee Sweeney, Krista Vandenborne, Glenn Walter, Jodi Wolff, Brenda Wong, Craig M McDonald, Members Of The Duchenne Regulatory Science Consortium Imaging-Dmd Consortium And The Cinrg Investigators
The Duchenne Regulatory Science Consortium (D-RSC) was established to develop tools to accelerate drug development for DMD.  The resulting tools are anticipated to meet validity requirements outlined by qualification/endorsement pathways at both the U.S. Food and Drug Administration (FDA) and European Medicines Administration (EMA), and will be made available to the drug development community. The initial goals of the consortium include the development of a disease progression model, with the goal of creating a model that would be used to forecast changes in clinically meaningful endpoints, which would inform clinical trial protocol development and data analysis...
January 12, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28228972/emergency-preparedness-and-management-at-the-university-of-l-aquila-central-italy-and-the-role-of-students-associations-in-the-april-6th-2009-earthquake
#20
Michele Magni, Rita Fraboni, Fausto Marincioni
INTRODUCTION: On April 6th 2009 an earthquake of Mw=6.3 hit the historical downtown of L'Aquila and its hinterland causing more than 300 fatalities and severe damage to private and public buildings. At the time, the University of L'Aquila represented a major source of employment and income for the city. The earthquake impacted both the facilities and the administrative, financial and patrimonial activities of the university, bringing into the open the tendency - widespread in Italy - to rely on adaptive tactics rather than on strategic pre-disaster plans...
January 12, 2017: PLoS Currents
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