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International Journal of General Medicine

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https://www.readbyqxmd.com/read/29773952/remote-ischemic-preconditioning-in-myocardial-protection-in-hemodialysis-patients
#1
Marcelo R Bacci, Livia Y Vasconcelos, Neif Murad, Antonio Carlos P Chagas, Ana Carolina Capuano, Beatriz Ca Alves, Edimar C Pereira, Ligia A Azzalis, Virginia Bc Junqueira, Fernando LA Fonseca
Background: Remote ischemic preconditioning (RIPC) is a procedure that generates a brief period of ischemia followed by reperfusion. The role of RIPC in protecting myocardial ischemia during hemodialysis is not yet established. The aim of the study was to evaluate RIPC myocardial protection as evaluated by ultrasensitive I troponin in hemodialysis outpatients. Patients and methods: A double-blind randomized trial with two groups: intervention submitted to RIPC and control group without RIPC...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29765244/an-echo-to-choosing-wisely-%C3%A2-in-switzerland
#2
Lionel Chok, Johann Debrunner, Sandra Jaeggli, Karmen Kusic, Esther B Bachli
Background: Inspired by the US Choosing Wisely® , in 2016 the Swiss Society of General Internal Medicine released a list of five treatments or diagnostic tests used in the hospital and considered unnecessary based on not improving patient care and adding to health care costs. These "Smarter Medicine" recommendations were implemented in the Department of Internal Medicine, Uster Hospital, in August 2016. They were supported by lectures and weekly email communications. We analyzed the number of blood draws before and after implementation of the recommendation aimed at reducing blood tests...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29731660/the-vitamin-d-receptor-and-the-etiology-of-rantes-ccl-expressive-fatty-degenerative-osteolysis-of-the-jawbone-an-interface-between-osteoimmunology-and-bone-metabolism
#3
Johann Lechner, Jürgen Aschoff, Tatjana Rudi
Background: Recent research on vitamin D indicates that our current understanding of the factors leading to chronic inflammation should be revised. One of the key mechanisms by which microbial immunosuppression occurs is the suppression of one of the most common endogenous cell nucleus receptors: the vitamin D receptor (VDR). Autoimmune diseases may be correlated with VDR deactivation (VDR-deac) which occurs when the receptor is no longer able to transcribe antimicrobial agents. Excess 1,25-dihydroxyvitamin D (1,25D) is not converted to 25-hydroxyvitamin D (25D); thus, high 1,25D levels may be accompanied by low 25D values...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29692623/nephritis-cerebritis-and-myositis-after-adalimumab-therapy-in-a-patient-with-rheumatoid-arthritis-a-case-report
#4
Narges E Omran, Abdulsalam A Noorwali
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that mainly affects the joints, therefore, may cause deformities and disability if untreated. The first line of treatment is disease-modifying antirheumatic drugs (DMARDs). When the patient fails to respond to DMARDs, mainly methotrexate, then second-line therapy is required. Tumor necrosis factor α (TNFα) plays an important role in the pathogenesis of RA; however, the treatment with anti-TNFα medications is challenging. It may trigger the autoimmune system and result in producing antibodies that induce symptoms and signs mimic to systemic lupus erythematosus (SLE), and in rare situations can affect vital organs with severe and life-threatening complications...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29692622/identifying-agents-triggering-bronchiolitis-in-the-state-of-qatar
#5
Mohamed A Hendaus, Ahmed H Alhammadi, Prem Chandra, Eshan Muneer, Mohamed S Khalifa
Background: Bronchiolitis is considered as the most frequent lower respiratory tract infection in infants and young children. This disorder is marked by acute inflammation, edema, damage of epithelial cells lining small airways, and augmentation of mucus production. Objective: The goal of the study was to identify agents triggering bronchiolitis in the State of Qatar. Materials and methods: A cross-sectional retrospective study was performed at Hamad Medical Corporation, the only tertiary and academic medical center in the State of Qatar...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29670391/determining-30-day-readmission-risk-for-heart-failure-patients-the-readmission-after-heart-failure-scale
#6
Ronald S Chamberlain, Jaswinder Sond, Krishnaraj Mahendraraj, Christine Sm Lau, Brianna L Siracuse
Background: Chronic heart failure (CHF), which affects >5 million Americans, accounts for >1 million hospitalizations annually. As a part of the Hospital Readmission Reduction Program, the Affordable Care Act requires that the Centers for Medicare and Medicaid Services reduce payments to hospitals with excess readmissions. This study sought to develop a scale that reliably predicts readmission rates among patients with CHF. Methods: The State Inpatient Database (2006-2011) was utilized, and discharge data including demographic and clinical characteristics on 642,448 patients with CHF from California and New York (derivation cohort) and 365,359 patients with CHF from Florida and Washington (validation cohort) were extracted...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29670390/epidemiological-factors-and-worldwide-pattern-of-middle-east-respiratory-syndrome-coronavirus-from-2013-to-2016
#7
Javad Aghazadeh-Attari, Iraj Mohebbi, Behnam Mansorian, Jamal Ahmadzadeh, Mohammad Mirza-Aghazadeh-Attari, Kazhal Mobaraki, Sima Oshnouei
Background: Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging threat to global health security with high intensity and lethality. This study was conducted to investigate epidemiological factors and patterns related to this disease. Methods: Full details of MERS-CoV cases available on the disease outbreak news section of the World Health Organization official website from January 2013 to November 2016 were retrieved; demographic and clinical information, global distribution status, potential contacts, and probable risk factors for the mortality of laboratory-confirmed MERS-CoV cases were extracted and analyzed by following standard statistical methods...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29636629/late-life-depression-issues-for-the-general-practitioner
#8
REVIEW
Axel Van Damme, Tom Declercq, Lieve Lemey, Hannelore Tandt, Mirko Petrovic
Late-life depression (LLD) is both a prevalent and life-threatening disorder, affecting up to 13.3% of the elderly population. LLD can be difficult to identify because patients mainly consult their general practitioner (GP) for somatic complaints. Moreover, patients may be hesitant to express the problem to their GP. Increased vigilance on the part of the GP can only benefit older people with depression. To recognize the risk of LLD, screening tools are provided in addition to treatment options for LLD. This review aims to provide the GP with guidance in recognizing and treating LLD...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29593428/can-patient-safety-be-improved-by-reducing-the-volume-of-inappropriate-prescribing-tasks-handed-over-to-out-of-hours-junior-doctors
#9
Samuel Martin Amis, Tobin Henry Edgar Osicki
Background: First-year doctors found that during out-of-hours shifts they were being delayed and distracted from reviewing potentially sick/deteriorating patients by a high volume of prescribing tasks. This predominately consisted of oral anticoagulation prescribing and rewrites of drug charts. We hoped that if we could reduce this burden of "inappropriate prescribing tasks", we could not only improve junior doctors' job satisfaction and opportunities for training but also give them more time for patient reviews...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29563829/psychiatric-traits-in-patients-with-vasovagal-and-unexplained-syncope
#10
Abdullah Alhuzaimi, Alwaleed Aljohar, Ahmad N Alhadi, Abdulqudous Aljenedil, Ahmad S Hersi
Purpose: Syncope is a common condition affecting almost one-third of the general population. The present study measures the prevalence of psychiatric traits in patients presenting with syncope (unexplained and vasovagal) and whether recurrent attacks have an impact on psychiatric profiles. Patients and methods: This is a case-control study in a tertiary hospital enrolling all patients aged ≥12 years with single or recurrent syncopal attacks. A self-reporting psychometric questionnaire (The Symptoms Checklist-90-Revised) was used to screen for depression, anxiety, somatization disorder, and phobia...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29563828/-pelargonium-sidoides-extract-eps-7630-a-review-of-its-clinical-efficacy-and-safety-for-treating-acute-respiratory-tract-infections-in-children
#11
REVIEW
Domenico Careddu, Andrea Pettenazzo
Background: In numerous randomized controlled trials (RCTs) and systematic reviews such as those published by the Cochrane Collaboration, Pelargonium sidoides extract EPs® 7630 was shown to be effective in acute respiratory tract infections (aRTI) in all investigated age-groups. This narrative review focuses on recently published results from RCTs investigating the clinical efficacy and safety of EPs 7630 in children and adolescents with different manifestations of aRTI, in order to present a broader overview and to provide an update on the state of knowledge regarding the use of EPs 7630 in this age-group...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29520161/knowledge-on-self-management-and-levels-of-asthma-control-among-adult-patients-in-ho-chi-minh-city-vietnam
#12
Vinh Nhu Nguyen, Thuong Thi Hoai Huynh, Niels H Chavannes
Background: Most asthma patients in Vietnam have poorly controlled asthma. Besides reasons related to the health care system and health care providers, knowledge on the self-management of patients has also contributed to this situation. Purpose: To assess knowledge on asthma self-management among adult asthma patients in Ho Chi Minh City. Patients and methods: A cross-sectional study with convenience sampling was conducted among 322 ambulatory patients using questionnaires filled in via a face-to-face interview...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29497327/erratum-perirenal-fat-stranding-is-not-a-powerful-diagnostic-tool-for-acute-pyelonephritis-corrigendum
#13
(no author information available yet)
[This corrects the article on p. 137 in vol. 10, PMID: 28507449.].
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29491715/a-video-depicting-resuscitation-did-not-impact-upon-patients-decision-making
#14
Caitlin Richardson-Royer, Imran Naqvi, Christopher Riffel, Lawrence Harvey, Domonique Smith, Dagmawe Ayalew, Nasim Motayar, Yaw Amoateng-Adjepong, Constantine A Manthous
Background: Previous studies have demonstrated that video of and scripted information about cardiopulmonary resuscitation (CPR) can be deployed during clinician-patient end-of-life discussions. Few studies, however, examine whether video adds to verbal information-sharing. We hypothesized that video augments script-only decision-making. Methods: Patients aged >65 years admitted to hospital wards were randomized to receive evidence-based information ("script") vs...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29491714/hospital-medicine-beyond-the-united-states
#15
REVIEW
Flora Kisuule, Eric Howell
Hospital medicine is the fastest growing specialty in the United States. An interesting aspect of the rapid expansion of hospital medicine is the expansion of the field beyond the United States. Although the health care systems, regulations, and cultural norms in these nations differ, there are striking similarities in the profession's development. We performed a literature review to better understand the factors contributing to the growth of hospital medicine internationally. In this article, we describe some of the drivers for expansion of hospital medicine outside the United States and the challenges faced by these groups...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29445294/anxiety-and-depression-in-general-practice-outpatients-the-long-term-change-process
#16
Fumio Shimada, Yoshiyuki Ohira, Yusuke Hirota, Akiko Ikegami, Takeshi Kondo, Kiyoshi Shikino, Shingo Suzuki, Kazutaka Noda, Takanori Uehara, Masatomi Ikusaka
Background and objectives: Patients who come for a consultation at a general practice clinic as outpatients often suffer from background anxiety and depression. The psychological state of such patients can alleviate naturally; however, there are cases when these symptoms persist. This study investigated the realities and factors behind anxiety/depression becoming prolonged. Methods: Participants were 678 adult patients, who came to Department of General Medicine at Chiba University Hospital within a 1-year period starting from April 2012 and who completed the Hospital Anxiety and Depression Scale (HADS) during their initial consultation...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29440924/alterations-in-oral-microbial-flora-induced-by-waterpipe-tobacco-smoking
#17
Muhamad Ali K Shakhatreh, Omar F Khabour, Karem H Alzoubi, Majed M Masadeh, Emad I Hussein, George N Bshara
Background: Waterpipe smoking is a global health problem and a serious public concern. Little is known about the effects of waterpipe smoking on oral health. In the current study, we examined the alterations of oral microbial flora by waterpipe smoking. Methods: One hundred adult healthy subjects (59 waterpipe smokers and 41 non-smokers) were recruited into the study. Swabs were taken from the oral cavity and subgingival regions. Standard culturing techniques were used to identify types, frequency, and mean number of microorganisms in cultures obtained from the subjects...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29430194/effectiveness-of-palivizumab-immunoprophylaxis-in-preterm-infants-against-respiratory-syncytial-virus-disease-in-qatar
#18
Ahmad Abushahin, Ibrahim Janahi, Amjad Tuffaha
Objective: The primary objective of this study was to document the hospitalization rate due to respiratory syncytial virus (RSV) and compliance with palivizumab use in preterm infants receiving palivizumab immunoprophylaxis during 2009-2012 RSV seasons. Design: This is a descriptive single-center cohort study. Infants who were ≤35-week gestational age were eligible for enrollment if they received the first palivizumab dose between November 1 and March 31 (2009-2010, 2010-2011, 2011-2012)...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29416371/survey-on-diabetic-patients-treated-with-insulin-during-the-fasting-month-of-ramadan
#19
Mohamed Abid, Mohamed Hsairi, Mouna Elleuch, Emna Ben Aissa
Aim: To estimate the proportion of diabetic patients on insulin, who interrupt fasting during Ramadan, and describe the reported reasons of this interruption. Design: This is a national observational survey of diabetic patients treated with insulin and fasting during the month of Ramadan 2013, proposed to all endocrinologists willing to participate. Consecutive patients were included until the required sample size, estimated at 498 patients, was obtained. Conducted among patients recruited by endocrinologists during the month following Ramadan 2013...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29403304/in-vitro-biofilm-formation-by-staphylococcus-aureus-isolated-from-wounds-of-hospital-admitted-patients-and-their-association-with-antimicrobial-resistance
#20
Puja Neopane, Hari Prasad Nepal, Rojeet Shrestha, Osamu Uehara, Yoshihiro Abiko
Introduction: Staphylococcus aureus including methicillin-resistant S. aureus (MRSA) has the propensity to form biofilms, and causes significant mortality and morbidity in the patients with wounds. Our aim was to study the in vitro biofilm-forming ability of S. aureus isolated from wounds of hospitalized patients and their association with antimicrobial resistance. Materials and methods: Forty-three clinical isolates of S. aureus were obtained from 150 pus samples using standard microbiological techniques...
2018: International Journal of General Medicine
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