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International Journal of General Medicine

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https://www.readbyqxmd.com/read/28293117/the-use-status-of-anticoagulation-drugs-for-inpatients-with-nonvalvular-atrial-fibrillation-in-southwest-china
#1
Huan Jie Zheng, Shu Kun Ouyang, Yue Zhao, Kai Lu, Su Xin Luo, Hua Xiao
BACKGROUND: Oral anticoagulants (OACs) are effective for the prophylaxis of stroke in patients with atrial fibrillation (AF). This cross-sectional study aimed to investigate the status of anticoagulation treatment for hospitalized AF patients in Southwest China. METHODS: A total of 4760 hospitalized patients with AF were enrolled from 21 hospitals in Chongqing city from January 1 to December 31, 2013. RESULTS: Among the enrolled patients, 3785 were diagnosed with nonvalvular AF...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28293116/how-french-general-practitioners-manage-and-prevent-recurrent-respiratory-tract-infections-in-children-the-sourirre-survey
#2
Bruno Chicoulaa, Hervé Haas, Jérôme Viala, Maryline Salvetat, Jean-Pierre Olives
BACKGROUND: Recurrent respiratory tract infections (RRTIs) are the most common reason for children's visits to primary care physicians in France; however, little is known about general practitioners' (GPs) opinions and expectations concerning the management and prevention of these common and recurrent pathologies. PURPOSE: To describe French GPs' daily practice in the management of respiratory infections and the prevention of their recurrence in children. METHODS: A sample group of French GPs answered a structured questionnaire on risk factors, RRTI management, antibiotic use and prevention measures...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28280379/amylmetacresol-2-4-dichlorobenzyl-alcohol-hexylresorcinol-or-carrageenan-lozenges-as-active-treatments-for-sore-throat
#3
Martina Morokutti-Kurz, Christine Graf, Eva Prieschl-Grassauer
Up to 80% of sore throats are caused by viruses. Several over the counter products are available which provide symptomatic, not causal relief. For such lozenges, containing the antiseptics and local anesthetics amylmetacresol (AMC) and 2,4-dichlorobenzyl alcohol (DCBA) or hexylresorcinol (HR), recently an additional virucidal effect was published. Therefore, we tested a set of Strepsils(®) lozenges, containing either HR (Max [#2]) or AMC/DCBA (Original [#3], Extra Strong [#4], Warm [#5], Orange and Vitamin C [#6], Sugar free Lemon [#7], Children/Strawberry [#8] and Soothing Honey and Lemon [#9]) for their antiviral efficiency against representatives of respiratory viruses known to cause sore throat: human rhinovirus (HRV) 1a, HRV8, influenza virus A H1N1n, Coxsackievirus A10, and human coronavirus (hCoV) OC43...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28260942/frequency-and-predictors-of-suboptimal-glycemic-control-in-an-african-diabetic-population
#4
Davis Kibirige, George Patrick Akabwai, Leaticia Kampiire, Daniel Ssekikubo Kiggundu, William Lumu
BACKGROUND: Persistent suboptimal glycemic control is invariably associated with onset and progression of acute and chronic diabetic complications in diabetic patients. In Uganda, studies documenting the magnitude and predictors of suboptimal glycemic control in adult ambulatory diabetic patients are limited. This study aimed at determining the frequency and predictors of suboptimal glycemic control in adult diabetic patients attending three urban outpatient diabetic clinics in Uganda...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28255252/hepatitis-c-treatment-where-are-we-now
#5
REVIEW
Nicholas J Burstow, Zameer Mohamed, Asmaa I Gomaa, Mark W Sonderup, Nicola A Cook, Imam Waked, C Wendy Spearman, Simon D Taylor-Robinson
Chronic hepatitis C infection affects millions of people worldwide and confers significant morbidity and mortality. Effective treatment is needed to prevent disease progression and associated complications. Previous treatment options were limited to interferon and ribavirin (RBV) regimens, which gave low cure rates and were associated with unpleasant side effects. The era of direct-acting antiviral (DAA) therapies began with the development of first-generation NS3/4A protease inhibitors in 2011. They vastly improved outcomes for patients, particularly those with genotype 1 infection, the most prevalent genotype globally...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28223838/factors-associated-with-body-mass-index-among-slum-dwelling-women-in-india-an-analysis-of-the-2005-2006-indian-national-family-health-survey
#6
Maya Laxmi Patel, Raywat Deonandan
BACKGROUND: Urbanization is increasing around the world, and in India, this trend has translated into an increase in the size of slum dwellings whose environments are suspected of being associated with poor health outcomes, particularly those relating to women's nutritional status. With this study, we sought to determine the factors associated with Indian women's body mass index (BMI) in slum environments, with special attention paid to women with tribal status. METHODS: A multiple linear regression analysis was performed on data from the Indian National Family Health Survey (2005-2006), modeling demographic and behavioral factors suspected of being associated with BMI, with additional focus on the measures of social class, specifically caste and tribal status...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28144158/following-the-results-of-the-empa-reg-outcome-trial-with-empagliflozin-is-it-possible-to-speak-of-a-class-effect
#7
Francisco Javier Ampudia-Blasco, Irene Romera, Bernat Ariño, Ramón Gomis
BACKGROUND: The recently published cardiovascular outcomes data for the first sodium-glucose cotransporter 2 (SGLT2) inhibitor, empagliflozin, have shown cardiovascular safety and additional benefits in patients with type 2 diabetes and established cardiovascular disease. Empagliflozin showed lower rates of death from cardiovascular causes or from any causes and lower hospitalization rates from heart failure compared with placebo, both in addition to standard care. This commentary discusses the existence of a possible class effect considering the available evidence described for other SGLT2 inhibitors...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28144157/the-correlation-between-preoperative-erythrocyte-sedimentation-rate-and-postoperative-outcome-in-adult-cardiac-surgery
#8
Eissa Bilehjani, Solmaz Fakhari, Haleh Farzin, Alireza Yaghoubi, Moussa Mirinazhad, Kamran Shadvar, Abbasali Dehghani, Pariasadat Aboalaiy
INTRODUCTION: Over the past decades, it has been recommended that preoperative assessment mainly relies on history and physical examination rather than unnecessary laboratory tests. In Iranian hospitals, erythrocyte sedimentation rate (ESR) has been routinely measured in most of the patients awaiting major surgery, which has in turn exacted heavy costs on the health system. Therefore, the aim of the present study was to assess the preoperative routine measurement of ESR in such patients...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28123312/insidious-onset-of-intermittent-claudication-as-the-primary-manifestation-of-infective-endocarditis
#9
George Vasquez-Rios, Maria T Gamero, Jesus De la Cruz, Gabriel A Hernandez, Eduardo Hernandez, Roy Dueñas
Musculoskeletal manifestations of infective endocarditis are well-described in the literature. However, insidious onset of localized calf pain is an uncommon presentation of embolization and may represent a diagnostic challenge owing to the nonspecific nature of the symptoms. This study reviewed the literature and reports a case of infective endocarditis in a patient who presented with bilateral calf pain as the primary complaint and reason for seeking medical attention.
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28096688/extreme-leukocytosis-and-leukemoid-reaction-associated-with-the-lung-sarcomatoid-carcinoma-an-unusual-case-report
#10
Danyang Wang, Haiyan Zhang, Fengkuan Yu, Baijun Fang
PURPOSE: To report a rare case of extreme leukocytosis and leukemoid reaction associated with lung sarcomatoid carcinoma (LSC) and increase people's awareness of the disease. PATIENTS AND METHODS: A 58-year-old male patient was diagnosed with LSC; however, after the end of the second course of chemotherapy, his white blood cells increased gradually without fever or use of medications such as granulocyte colony-stimulating factor and steroids. A bone marrow biopsy then confirmed it to be a leukemoid reaction...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28053553/hepatitis-c-in-egypt-past-present-and-future
#11
REVIEW
Ahmed Elgharably, Asmaa I Gomaa, Mary Me Crossey, Peter J Norsworthy, Imam Waked, Simon D Taylor-Robinson
Hepatitis C viral infection is endemic in Egypt with the highest prevalence rate in the world. It is widely accepted that the implementation of mass population antischistosomal treatment involving administration of tartar emetic injections (from 1950s to 1980s) led to widespread infection. What is less well known, however, is that these schemes were implemented by the Egyptian Ministry of Health on the advice of the World Health Organization. There has been a spectrum of treatments to target the public health disaster represented by the hepatitis C problem in Egypt: from the use of PEGylated interferon to the recent use of direct acting antiviral drugs...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28008280/thicker-carotid-intima-media-thickness-and-increased-plasma-vegf-levels-suffered-by-post-acute-thrombotic-stroke-patients
#12
Yuyun Yueniwati, Ni Komang Darmiastini, Eko Arisetijono
BACKGROUND AND OBJECTIVES: Atherosclerosis causes reduction of the oxygen supply to structures in the far arterial wall, provoking the release of factors that drive angiogenesis of vasa vasorum, including VEGF. Other studies have revealed the inflammatory response in atherosclerosis and the role of platelet factor 4 (PF4) as an anti-angiogenic chemokine through the inhibition of VEGF. This cross-sectional study aims at measuring the effect of atherosclerosis assessed through carotid intima-media thickness (CIMT) against plasma VEGF levels in patients with post-acute thrombotic stroke...
2016: International Journal of General Medicine
https://www.readbyqxmd.com/read/27980433/bacteremia-caused-by-a-rare-pathogen-chromobacterium-violaceum-a-case-report-from-nepal
#13
Narayan Prasad Parajuli, Anjeela Bhetwal, Sumitra Ghimire, Anjila Maharjan, Shreena Shakya, Deepa Satyal, Roshan Pandit, Puspa Raj Khanal
Chromobacterium violaceum is a gram negative saprophytic bacterium, prevalent in tropical and subtropical climates. Infections caused by C. violaceum are very uncommon, yet it can cause severe systemic infections with higher mortality when entered into the bloodstream through open wound. A case of symptomatic bacteremia in a woman caused by C. violaceum was identified recently at a tertiary care teaching hospital in Nepal. Timely diagnosis by microbiological methods and rapid administration of antimicrobials led to a successful treatment of this life-threatening infection in this case...
2016: International Journal of General Medicine
https://www.readbyqxmd.com/read/27956843/lung-protective-mechanical-ventilation-strategies-in-cardiothoracic-critical-care-a-retrospective-study
#14
Vasileios Zochios, Matthew Hague, Kimberly Giraud, Nicola Jones
A body of evidence supports the use of low tidal volumes in ventilated patients without lung pathology to slow progress to acute respiratory distress syndrome (ARDS) due to ventilator associated lung injury. We undertook a retrospective chart review and tested the hypothesis that tidal volume is a predictor of mortality in cardiothoracic (medical and surgical) critical care patients receiving invasive mechanical ventilation. Independent predictors of mortality in our study included: type of surgery, albumin, H(+), bilirubin, and fluid balance...
2016: International Journal of General Medicine
https://www.readbyqxmd.com/read/27956842/role-of-a-proprietary-propolis-based-product-on-the-wait-and-see-approach-in-acute-otitis-media-and-in-preventing-evolution-to-tracheitis-bronchitis-or-rhinosinusitis-from-nonstreptococcal-pharyngitis
#15
Francesco Di Pierro, Alberto Zanvit, Maria Colombo
Antipyretics and/or anti-inflammatory drugs along with a wait-and-see approach are the only treatments recommended in early acute otitis media (AOM) or viral pharyngitis. Propolis has been widely investigated for its antibacterial, antiviral, and anti-inflammatory properties and could perhaps be administered as an add-on therapy during watchful waiting in AOM or for better control of symptoms in nonstreptococcal pharyngitis. However, propolis has well-known problems of poor solubility and low oral bioavailability...
2016: International Journal of General Medicine
https://www.readbyqxmd.com/read/27920571/commercial-test-kits-for-detection-of-lyme-borreliosis-a-meta-analysis-of-test-accuracy
#16
Michael J Cook, Basant K Puri
The clinical diagnosis of Lyme borreliosis can be supported by various test methodologies; test kits are available from many manufacturers. Literature searches were carried out to identify studies that reported characteristics of the test kits. Of 50 searched studies, 18 were included where the tests were commercially available and samples were proven to be positive using serology testing, evidence of an erythema migrans rash, and/or culture. Additional requirements were a test specificity of ≥85% and publication in the last 20 years...
2016: International Journal of General Medicine
https://www.readbyqxmd.com/read/27895508/multi-ethnic-differences-in-hba1c-blood-pressure-and-low-density-lipid-cholesterol-control-among-south-africans-living-with-type-2-diabetes-after-a-4-year-follow-up
#17
Yacob Pinchevsky, Varada J Shukla, Neil Butkow, Tobias Chirwa, Frederick Raal
PURPOSE: Our study set out to examine if disparities in control of glycated hemoglobin (HbA1c), blood pressure (BP), and low-density-lipoprotein cholesterol (LDL-C) existed among an urban multi-ethnic cohort of South Africans, living with type 2 diabetes mellitus (T2DM). PATIENTS AND METHODS: This longitudinal, retrospective study consisted of 261 men and women with previously diagnosed T2DM who attended Charlotte Maxeke Johannesburg Academic Hospital, South Africa across two time periods 2009 and 2013...
2016: International Journal of General Medicine
https://www.readbyqxmd.com/read/27877063/copd-patients-medical-care-and-support-in-greece-during-financial-crisis
#18
George Mitonas, Alexia Juvana, Zoe Daniil, Chryssa Hatzoglou, Konstantinos Gourgoulianis
BACKGROUND: The need to follow a multidisciplinary strategy in chronic obstructive pulmonary disease (COPD) management and rehabilitation in community settings in Greece raises significant questions, given the severe austerity measures being imposed at present. The aim of this study was to investigate the clinical profile of patients with COPD along with the care provided in rural community settings in Greece. METHODS: Two primary health care centers and 200 newly diagnosed patients over a 12-month period were involved in the study...
2016: International Journal of General Medicine
https://www.readbyqxmd.com/read/27843336/treatment-of-bleeding-in-acquired-hemophilia-a-with-the-proper-administration-of-recombinant-activated-factor-vii-single-center-study-of-7-cases
#19
Makoto Saito, Minoru Kanaya, Koh Izumiyama, Akio Mori, Tatsuro Irie, Masanori Tanaka, Masanobu Morioka, Masahiro Ieko
Recombinant activated factor VII (rFVIIa) is the bypassing agent used in the first-line hemostatic therapy for acquired hemophilia A (AHA); however, the occurrence of thrombotic complications in rFVIIa-treated AHA patients was recently reported to be 2.9-6.5%. Therefore, the investigation of the proper administration of rFVIIa for AHA is needed. In the present study, we retrospectively investigated the clinical features of AHA with regards to the use of rFVIIa (presence or absence of use and total amount) in 7 AHA patients encountered in our department for 7 years between January 2008 and December 2014...
2016: International Journal of General Medicine
https://www.readbyqxmd.com/read/27843335/incidence-of-clinical-symptoms-during-long-duration-orbital-spaceflight
#20
Brian Crucian, Adriana Babiak-Vazquez, Smith Johnston, Duane L Pierson, C Mark Ott, Clarence Sams
BACKGROUND: The environment of spaceflight may elevate an astronaut's clinical risk for specific diseases. The purpose of this study was to derive, as accurately as currently possible, an assessment of in-flight clinical "incidence" data, based on observed clinical symptoms in astronauts on board the International Space Station (ISS). METHODS: Electronic medical records were examined from 46 long-duration ISS crew members, each serving approximately a 6-month mission on board the ISS, constituting 20...
2016: International Journal of General Medicine
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