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International Journal of General Medicine

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https://www.readbyqxmd.com/read/29988742/the-increasing-prevalence-of-non-communicable-diseases-in-low-middle-income-countries-the-view-from-malawi
#1
REVIEW
Matthew Gowshall, Simon D Taylor-Robinson
Non-communicable diseases (NCDs) are the leading cause of death globally, the majority of these being due to cardiovascular disease, cancer, chronic respiratory diseases, or diabetes. Mortality from many NCDs continues to increase worldwide, with a disproportionately larger impact in low-middle income countries (LMIs), where almost 75% of global deaths occur from these causes. As a low-income African country that consistently ranks amongst the world's poorest nations, Malawi as a case study demonstrates how transition due to societal change and increasing urbanization is often accompanied by a rise in the rate of NCDs...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29950885/understanding-short-term-blood-pressure-variability-phenotypes-from-concept-to-clinical-practice
#2
REVIEW
Veerendra Melagireppa Chadachan, Min Tun Ye, Jam Chin Tay, Kannan Subramaniam, Sajita Setia
Clinic blood pressure (BP) is recognized as the gold standard for the screening, diagnosis, and management of hypertension. However, optimal diagnosis and successful management of hypertension cannot be achieved exclusively by a handful of conventionally acquired BP readings. It is critical to estimate the magnitude of BP variability by estimating and quantifying each individual patient's specific BP variations. Short-term BP variability or exaggerated circadian BP variations that occur within a day are associated with increased cardiovascular events, mortality and target-organ damage...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29950884/stroke-in-hospital-survival-and-its-predictors-the-first-results-from-tabriz-stroke-registry-of-iran
#3
Reza Deljavan, Mehdi Farhoudi, Homayoun Sadeghi-Bazargani
Objective: The aim of this study was to determine the in-hospital survival of patients referred to the 2 stroke centers in North-West of Iran during a full seasonal year from April 2015. Methods: All the consecutive patients with stroke admitted to the 2 main stroke centers at Tabriz (Imam Reza University Hospital and Razi University Hospital) were recruited in this study. Stroke patients from both ischemic and hemorrhagic subtypes were selected based on the registry data and International Classification of Diseases, 10th edition...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29950883/venous-thromboembolism-risk-assessments-on-trauma-patients-has-suboptimal-interobserver-reliability-among-inexperienced-clinicians-fourth-year-medical-students
#4
Akella Chendrasekhar, Sireesha Aleti
Background: Venous thromboembolic disease is a major cause of morbidity and mortality in hospitalized patients worldwide. The objective of this study is to compare interobserver reliability for qualitative and quantitative venous thromboembolism (VTE) risk assessments in hospitalized trauma patients. Methods: We conducted a retrospective medical record review of 40 randomly selected trauma patients admitted to a 448-bed urban level-I trauma center from January 2013 to January 2014...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29942144/association-of-serum-procalcitonin-and-c-reactive-protein-levels-with-curb-65-criteria-among-patients-with-community-acquired-pneumonia
#5
Fariba Keramat, Hamid Reza Ghasemi Basir, Elham Abdoli, Arghavan Shafiei Aghdam, Jalal Poorolajal
Background: The concentration of diagnostic markers such as inflammatory biomarkers including procalcitonin (PCT) and C-reactive protein (CRP) increases in bacterial infections. The aim of this study was to compare serum PCT and CRP levels with CURB-65 ranking, in the patients with community-acquired pneumonia (CAP). Patients and methods: In a cross-sectional study, 93 hospitalized patients with a definite diagnosis of CAP, considering inclusion and exclusion criteria, were enrolled...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29892202/clinical-and-epidemiologic-profile-and-predictors-of-outcome-of-poisonous-snake-bites-an-analysis-of-1-500-cases-from-a-tertiary-care-center-in-malabar-north-kerala-india
#6
Kg Sajeeth Kumar, Santhosh Narayanan, V Udayabhaskaran, N K Thulaseedharan
Background: Snake bites are a neglected public health problem in all tropical countries, and particularly in Malabar region of Kerala, India. Demographic characteristics and clinical parameters vary in this part of the world, and studies based on them are scarce. Increased incidence of capillary leak syndrome (CLS) in hemotoxic snake bites and emergence of cases of hump-nosed pit viper (HNPV, Hypnale hypnale ) envenomation are some notable features seen here. Objectives: The study was conducted to assess the epidemiological profile and clinical features to identify factors contributing to outcome in patients with venomous snakebites...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29872334/overview-of-air-pollution-and-endocrine-disorders
#7
REVIEW
Philippa D Darbre
Over recent years, many environmental pollutant chemicals have been shown to possess the ability to interfere in the functioning of the endocrine system and have been termed endocrine disrupting chemicals (EDCs). These compounds exist in air as volatile or semi-volatile compounds in the gas phase or attached to particulate matter. They include components of plastics (phthalates, bisphenol A), components of consumer goods (parabens, triclosan, alkylphenols, fragrance compounds, organobromine flame retardants, fluorosurfactants), industrial chemicals (polychlorinated biphenyls), products of combustion (polychlorinated dibenzodioxins/furans, polyaromatic hydrocarbons), pesticides, herbicides, and some metals...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29844698/exploring-factors-that-might-influence-primary-care-provider-discussion-of-and-recommendation-for-prostate-and-colon-cancer-screening
#8
Christine E Kistler, Maihan Vu, Anne Sutkowi-Hemstreet, Ziya Gizlice, Russell P Harris, Noel T Brewer, Carmen L Lewis, Rowena J Dolor, Colleen Barclay, Stacey L Sheridan
Background: Primary-care providers may contribute to the use of low-value cancer screening. Objective: We sought to examine circumstances under which primary-care providers would discuss and recommend two types of cancer screening services across a spectrum of net benefit and other factors known to influence screening. Patients and methods: This was a cross sectional survey of 126 primary-care providers in 24 primary-care clinics in the US...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29773952/remote-ischemic-preconditioning-in-myocardial-protection-in-hemodialysis-patients
#9
Marcelo R Bacci, Livia Y Vasconcelos, Neif Murad, Antonio Carlos P Chagas, Ana Carolina Capuano, Beatriz Ca Alves, Edimar C Pereira, Ligia A Azzalis, Virginia Bc Junqueira, Fernando LA Fonseca
Background: Remote ischemic preconditioning (RIPC) is a procedure that generates a brief period of ischemia followed by reperfusion. The role of RIPC in protecting myocardial ischemia during hemodialysis is not yet established. The aim of the study was to evaluate RIPC myocardial protection as evaluated by ultrasensitive I troponin in hemodialysis outpatients. Patients and methods: A double-blind randomized trial with two groups: intervention submitted to RIPC and control group without RIPC...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29765244/an-echo-to-choosing-wisely-%C3%A2-in-switzerland
#10
Lionel Chok, Johann Debrunner, Sandra Jaeggli, Karmen Kusic, Esther B Bachli
Background: Inspired by the US Choosing Wisely® , in 2016 the Swiss Society of General Internal Medicine released a list of five treatments or diagnostic tests used in the hospital and considered unnecessary based on not improving patient care and adding to health care costs. These "Smarter Medicine" recommendations were implemented in the Department of Internal Medicine, Uster Hospital, in August 2016. They were supported by lectures and weekly email communications. We analyzed the number of blood draws before and after implementation of the recommendation aimed at reducing blood tests...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29731660/the-vitamin-d-receptor-and-the-etiology-of-rantes-ccl-expressive-fatty-degenerative-osteolysis-of-the-jawbone-an-interface-between-osteoimmunology-and-bone-metabolism
#11
Johann Lechner, Jürgen Aschoff, Tatjana Rudi
Background: Recent research on vitamin D indicates that our current understanding of the factors leading to chronic inflammation should be revised. One of the key mechanisms by which microbial immunosuppression occurs is the suppression of one of the most common endogenous cell nucleus receptors: the vitamin D receptor (VDR). Autoimmune diseases may be correlated with VDR deactivation (VDR-deac) which occurs when the receptor is no longer able to transcribe antimicrobial agents. Excess 1,25-dihydroxyvitamin D (1,25D) is not converted to 25-hydroxyvitamin D (25D); thus, high 1,25D levels may be accompanied by low 25D values...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29692623/nephritis-cerebritis-and-myositis-after-adalimumab-therapy-in-a-patient-with-rheumatoid-arthritis-a-case-report
#12
Narges E Omran, Abdulsalam A Noorwali
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that mainly affects the joints, therefore, may cause deformities and disability if untreated. The first line of treatment is disease-modifying antirheumatic drugs (DMARDs). When the patient fails to respond to DMARDs, mainly methotrexate, then second-line therapy is required. Tumor necrosis factor α (TNFα) plays an important role in the pathogenesis of RA; however, the treatment with anti-TNFα medications is challenging. It may trigger the autoimmune system and result in producing antibodies that induce symptoms and signs mimic to systemic lupus erythematosus (SLE), and in rare situations can affect vital organs with severe and life-threatening complications...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29692622/identifying-agents-triggering-bronchiolitis-in-the-state-of-qatar
#13
Mohamed A Hendaus, Ahmed H Alhammadi, Prem Chandra, Eshan Muneer, Mohamed S Khalifa
Background: Bronchiolitis is considered as the most frequent lower respiratory tract infection in infants and young children. This disorder is marked by acute inflammation, edema, damage of epithelial cells lining small airways, and augmentation of mucus production. Objective: The goal of the study was to identify agents triggering bronchiolitis in the State of Qatar. Materials and methods: A cross-sectional retrospective study was performed at Hamad Medical Corporation, the only tertiary and academic medical center in the State of Qatar...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29670391/determining-30-day-readmission-risk-for-heart-failure-patients-the-readmission-after-heart-failure-scale
#14
Ronald S Chamberlain, Jaswinder Sond, Krishnaraj Mahendraraj, Christine Sm Lau, Brianna L Siracuse
Background: Chronic heart failure (CHF), which affects >5 million Americans, accounts for >1 million hospitalizations annually. As a part of the Hospital Readmission Reduction Program, the Affordable Care Act requires that the Centers for Medicare and Medicaid Services reduce payments to hospitals with excess readmissions. This study sought to develop a scale that reliably predicts readmission rates among patients with CHF. Methods: The State Inpatient Database (2006-2011) was utilized, and discharge data including demographic and clinical characteristics on 642,448 patients with CHF from California and New York (derivation cohort) and 365,359 patients with CHF from Florida and Washington (validation cohort) were extracted...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29670390/epidemiological-factors-and-worldwide-pattern-of-middle-east-respiratory-syndrome-coronavirus-from-2013-to-2016
#15
Javad Aghazadeh-Attari, Iraj Mohebbi, Behnam Mansorian, Jamal Ahmadzadeh, Mohammad Mirza-Aghazadeh-Attari, Kazhal Mobaraki, Sima Oshnouei
Background: Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging threat to global health security with high intensity and lethality. This study was conducted to investigate epidemiological factors and patterns related to this disease. Methods: Full details of MERS-CoV cases available on the disease outbreak news section of the World Health Organization official website from January 2013 to November 2016 were retrieved; demographic and clinical information, global distribution status, potential contacts, and probable risk factors for the mortality of laboratory-confirmed MERS-CoV cases were extracted and analyzed by following standard statistical methods...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29636629/late-life-depression-issues-for-the-general-practitioner
#16
REVIEW
Axel Van Damme, Tom Declercq, Lieve Lemey, Hannelore Tandt, Mirko Petrovic
Late-life depression (LLD) is both a prevalent and life-threatening disorder, affecting up to 13.3% of the elderly population. LLD can be difficult to identify because patients mainly consult their general practitioner (GP) for somatic complaints. Moreover, patients may be hesitant to express the problem to their GP. Increased vigilance on the part of the GP can only benefit older people with depression. To recognize the risk of LLD, screening tools are provided in addition to treatment options for LLD. This review aims to provide the GP with guidance in recognizing and treating LLD...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29593428/can-patient-safety-be-improved-by-reducing-the-volume-of-inappropriate-prescribing-tasks-handed-over-to-out-of-hours-junior-doctors
#17
Samuel Martin Amis, Tobin Henry Edgar Osicki
Background: First-year doctors found that during out-of-hours shifts they were being delayed and distracted from reviewing potentially sick/deteriorating patients by a high volume of prescribing tasks. This predominately consisted of oral anticoagulation prescribing and rewrites of drug charts. We hoped that if we could reduce this burden of "inappropriate prescribing tasks", we could not only improve junior doctors' job satisfaction and opportunities for training but also give them more time for patient reviews...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29563829/psychiatric-traits-in-patients-with-vasovagal-and-unexplained-syncope
#18
Abdullah Alhuzaimi, Alwaleed Aljohar, Ahmad N Alhadi, Abdulqudous Aljenedil, Ahmad S Hersi
Purpose: Syncope is a common condition affecting almost one-third of the general population. The present study measures the prevalence of psychiatric traits in patients presenting with syncope (unexplained and vasovagal) and whether recurrent attacks have an impact on psychiatric profiles. Patients and methods: This is a case-control study in a tertiary hospital enrolling all patients aged ≥12 years with single or recurrent syncopal attacks. A self-reporting psychometric questionnaire (The Symptoms Checklist-90-Revised) was used to screen for depression, anxiety, somatization disorder, and phobia...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29563828/-pelargonium-sidoides-extract-eps-7630-a-review-of-its-clinical-efficacy-and-safety-for-treating-acute-respiratory-tract-infections-in-children
#19
REVIEW
Domenico Careddu, Andrea Pettenazzo
Background: In numerous randomized controlled trials (RCTs) and systematic reviews such as those published by the Cochrane Collaboration, Pelargonium sidoides extract EPs® 7630 was shown to be effective in acute respiratory tract infections (aRTI) in all investigated age-groups. This narrative review focuses on recently published results from RCTs investigating the clinical efficacy and safety of EPs 7630 in children and adolescents with different manifestations of aRTI, in order to present a broader overview and to provide an update on the state of knowledge regarding the use of EPs 7630 in this age-group...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29520161/knowledge-on-self-management-and-levels-of-asthma-control-among-adult-patients-in-ho-chi-minh-city-vietnam
#20
Vinh Nhu Nguyen, Thuong Thi Hoai Huynh, Niels H Chavannes
Background: Most asthma patients in Vietnam have poorly controlled asthma. Besides reasons related to the health care system and health care providers, knowledge on the self-management of patients has also contributed to this situation. Purpose: To assess knowledge on asthma self-management among adult asthma patients in Ho Chi Minh City. Patients and methods: A cross-sectional study with convenience sampling was conducted among 322 ambulatory patients using questionnaires filled in via a face-to-face interview...
2018: International Journal of General Medicine
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