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Journal of Atrial Fibrillation

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https://www.readbyqxmd.com/read/29487686/safety-and-efficacy-of-inpatient-initiation-of-dofetilide-versus-sotalol-for-atrial-fibrillation
#1
Bharath Yarlagadda, Venkat Vuddanda, Tawseef Dar, Mohammad-Ali Jazayeri, Valay Parikh, Mohit K Turagam, Madhav Lavu, Sindhu Reddy Avula, Donita Atkins, Sudharani Bommana, Rakesh Gopinathannair, Madhu Reddy Yeruva, Dhanunjaya Lakkireddy
Background: We sought to investigate and compare the safety and efficacy of two commonly used antiarrhythmic drugs, Dofetilide (DF) and Sotalol (SL), during inpatient drug initiation in patients with symptomatic atrial fibrillation (AF). Methods: We performed a single center retrospective study of consecutive patients, admitted for initiation of either DF or SL, for AF between 2012 and 2015. Rates of successful cardioversion, QT interval prolongation, adverse events and drug discontinuations were calculated and compared...
December 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29487685/management-of-stroke-risk-in-atrial-fibrillation-patients-with-bleeding-on-oral-anticoagulation-therapy-role-of-left-atrial-appendage-closure-octreotide-and-more
#2
REVIEW
Tawseef Dar, Bharat Yarlagadda, James Vacek, Buddhadeb Dawn, Dhanunjaya Lakkireddy
Background: Bleeding complications especially gastrointestinal bleeding remains a major challenge associated with oral anticoagulation therapy (OAT) and often leads clinicians to withdraw oral anticoagulation therapy (OAT) . This exposes patients to risk of stroke and systemic thromboembolism (STE). Novel oral anticoagulants (NOACs) have proved no better when it comes to bleeding events and in fact studies have shown that overall NOACs are associated with higher incidence of gastrointestinal (GI) bleeding compared to warfarin ...
December 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29487684/electrocardiogram-ecg-for-the-prediction-of-incident-atrial-fibrillation-an-overview
#3
REVIEW
Yoshifusa Aizawa, Hiroshi Watanabe, Ken Okumura
Electrocardiograms (ECGs) have been employed to medically evaluate participants in population-based studies, and ECG-derived predictors have been reported for incident atrial fibrillation (AF). Here, we reviewed the status of ECG in predicting new-onset AF. We surveyed population-based studies and revealed ECG variables to be risk factors for incident AF. When available, the predictive values of each ECG risk marker were calculated. Both the atrium-related and ventricle-related ECG variables were risk factors for incident AF, with significant hazard risks (HRs) even after multivariate adjustments...
December 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29487683/successful-denovo-implantation-and-explanation-of-an-old-malfunctioning-micratm-leadless-pacemaker
#4
Muhammad R Afzal, Tawseef Dar, Mahmoud Houmsse, Ralph Augostini, Emile G Daoud, John Hummel
An unknown mass in the left atrium can be challenging to differentiate, especially after previous heart transplant. A precise diagnosis is clinically crucial because of the therapeutic implications. CMR is a useful, non-invasive tool to distinguish intra-cardiac lesions, thereby enabling clinicians to initiate adequate therapy.
December 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29487682/reduced-p-wave-voltage-in-lead-i-is-associated-with-development-of-atrial-fibrillation-in-patients-with-coronary-artery-disease
#5
Bryce Alexander, Sohaib Haseeb, Henri van Rooy, Gary Tse, Wilma Hopman, Manuel Martinez-Selles, Antoni Bayés de Luna, Göksel Çinier, Adrian Baranchuk
Background: Reduced P-wave voltage in lead 1 (PVL1) has been associated with atrial fibrillation (AF) recurrence.This study sought to determine the association between reduced PVL1 and AF in the NSTEMI population and the correlation between reduced PVL1 and interatrial block (IAB)/coronary artery disease (CAD). Methods: Data were recorded for clinical, echocardiographic, angiographic, electrocardiographic and outcome variables. Patients were followed for a minimum of one year...
December 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29487681/surgical-epicardial-left-atrial-appendage-closure-a-true-alternative
#6
Sacha Salzberg, Maximillian Emmert
Left atrial appendage closure was originally described by Madden in 1949 who was the first to perform appendix amputation. This was a very invasive procedure with poor outcome, but preformed for stroke prevention. Much later, it was James Cox whom described the Cox-Maze procedure, which included multiple incisions to create a maze like pathway for the electrical impulse to go undisturbed from the sinus node down to the atrio-ventricular node. Since then cardiac surgeons stopped focusing on the left atrial appendage and went on about seemingly more important things...
December 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29487680/left-atrial-appendage-occlusion-with-amplatzer-cardiac-plug-and-amplatzer-amulet-a-clinical-trials-update
#7
REVIEW
Apostolos Tzikas
It has been over a decade since dedicated Amplatzer devices have been used for left atrial appendage occlusion (LAAO) in patients with atrial fibrillation. The first was the Amplatzer Cardiac Plug (ACP) that is now replaced in most countries by the Amplatzer Amulet device. Most of the clinical data for ACP come from the ACP multicenter registry that included 1047 patients from 22 sites, whereas the largest to date report on the Amplatzer Amulet is a recently published prospective multicenter study in 1088 patients from 64 sites...
December 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29487679/left-atrial-strain-predicts-pro-thrombotic-state-in-patients-with-non-valvular-atrial-fibrillation
#8
Matteo Cameli, Stefano Lunghetti, Giulia Elena Mandoli, Francesca Maria Righini, Matteo Lisi, Valeria Curci, Cristina Di Tommaso, Marco Solari, Dan Nistor, Annalaura Gismondi, Marta Focardi, Roberto Favilli, Sergio Mondillo
Background and Purpose: Atrial fibrillation (AF) has a high prevalence in the population and it is responsible for up to the 25% of the strokes in elderly people. The aim of our study was to assess the correlations of left atrial (LA) functional parameter, global peak atrial longitudinal strain (PALS), derived from speckle tracking echocardiography (STE), with transesophageal echocardiography (TEE) findings in patients with persistent AF undergoing TEE before electrical cardioversion or ablation procedures...
December 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29487678/reversal-agents-in-the-era-of-noacs
#9
REVIEW
Hany S Abed, Michael J Kilborn, Vivien Chen, Raymond W Sy
The incidence and prevalence of atrial fibrillation (AF) is expected to more than double between 2010 and 2030. Accordingly, the use of non-vitamin K oral anticoagulant (NOAC) agents for thromboembolic stroke prevention is anticipated to increase. The development of effective and safe antidotes is needed to address the unmet need for rapid anticoagulation reversal. The immediate role for these novel antidotes is for reversal of NOAC activity in life threatening bleeding and urgent surgical intervention. In addition, reversal agents may play an important role in simplifying bridging protocols in the peri-procedural period for catheter ablation of AF and elective surgery...
December 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29487677/beating-heart-thoracoscopic-left-atrial-appendage-exclusion-in-a-patient-with-left-atrial-thrombus
#10
Ali Khoynezhad
Stroke remains a major complication of atrial fibrillation and third leading cause of death in Western Countries. [1] While Coumadin and novel oral anticoagulants have been efficient in reducing the stoke risk in patients with atrial fibrillation; there is a subset of patients who are not candidates for anticoagulation.[2] The management of these patients is clinical challenge.We describe a patient with history of permanent atrial fibrillation with contra-indication to anticoagulation presenting with and left atrial thrombus...
December 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29487676/complications-of-atrial-fibrillation-cryoablation
#11
REVIEW
Ugur Canpolat, Duygu Kocyigit, Kudret Aytemir
Catheter ablation either by using radiofrequency or cryo energy in symptomatic patients with atrial fibrillation (AF) has shown to be effective as compared to anti-arrhythmic drugs. However, all the techniques used during AF ablation are not free of complication. There are several well-known peri-procedural complications in which operators should be informed of the possible risks, cautious during the procedure and able to manage them when occurred. Herein, we aimed to review possible complications of AF cryoablation...
December 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29487675/tumor-or-thrombus-the-role-of-cardiac-magnetic-resonance-imaging-in-differentiating-left-atrial-mass-in-a-transplanted-heart-a-case-report
#12
Timm Seewöster, Sebastian Hilbert, Ricardo A Spampinato, Jochen Hahn, Gerhard Hindricks, Andreas Bollmann, Paetsch Ingo, Jahnke Cosima
An unknown mass in the left atrium can be challenging to differentiate, especially after previous heart transplant. A precise diagnosis is clinically crucial because of the therapeutic implications. CMR is a useful, non-invasive tool to distinguish intra-cardiac lesions, thereby enabling clinicians to initiate adequate therapy.
December 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29487674/left-ventricular-systolic-function-assessed-by-global-longitudinal-strain-is-impaired-in-atrial-fibrillation-compared-to-sinus-rhythm
#13
Bue F Ross Agner, Michael G Katz, Zachary R Williams, Ulrik Dixen, Gorm B Jensen, Karl Q Schwarz
Background: Atrial fibrillation (AF) is the most common aberrant cardiac arrhythmia. Many AF patients present with symptoms of dyspnea and fatigue, but have normal left ventricular ejection fraction (LVEF). Purpose: To determine the reproducibility of measurements of global longitudinal strain (GLS) and strain rate in patients with AF and examine if the arrhythmia is associated with abnormal LV strain and strain rate independent of age, sex, heart rate, LVEF and LV mass...
December 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29250249/arrhythmia-induced-cardiomyopathy-prevalent-under-recognized-reversible
#14
Rahul Dhawan, Rakesh Gopinathannair
Arrhythmia-induced cardiomyopathy (AIC) is a clinical condition in which a persistent tachyarrhythmia or frequent ectopy contribute to ventricular dysfunction leading to systolic heart failure. AIC can be partially or completely corrected with adequate treatment of the culprit arrhythmia. Several molecular and cellular alterations by which tachyarrhythmias lead to cardiomyopathy have been identified. AIC can affect children and adults, can be clinically silent in the form of asymptomatic tachycardia with cardiomyopathy, or can present with manifest heart failure...
October 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29250248/congenital-absence-of-left-atrial-appendage
#15
Tawseef Dar, Bharath Yarlagadda, Vijendra Swarup, Dhanunjaya Lakkireddy
Isolated absence of left atrial appendage is a very rare entity and is usually encountered as an incidental finding during routine imaging for other purposes. Lately, with increasing fund of knowledge about its potential role in cardio embolic phenomena, we have seen an increased trend in the use different techniques to exclude left atrial appendage from main left atrial chamber, in an effort to alleviate the stroke risk and therefore the need for long term anticoagulation. Clinical implications of absent left atrial appendage in such patients remains a mystery...
October 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29250247/coronary-air-embolism-during-cryoablation-of-atrial-fibrillation-a-catastrophic-complication-and-its-management
#16
Serkan Cay, Ozcan Ozeke, Firat Ozcan, Serkan Topaloglu, Dursun Aras
Various acute complications and their management during ablation of atrial fibrillation have been described. In the current report, coronary air embolism, its acute adverse effects and management of the problem were presented in a patient underwent cryoballoon ablation of atrial fibrillation.
October 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29250246/leaks-after-left-atrial-appendage-ligation-with-lariat-device-incidence-pathophysiology-clinical-implications-and-methods-of-closure-a-case-based-discussion
#17
Bharath Yarlagadda, Valay Parikh, Tawseef Dar, Dhanunjaya Lakkireddy
Catheter based left atrial appendage (LAA) closure techniques are emerging as a promising alternative for stroke prevention in patients who cannot tolerate oral anticoagulation. Lariat procedure involves percutaneous catheter based epicardial ligation of the LAA with a suture via an endo-epicardial hybrid approach. It offers the advantage of not leaving behind a focus for thrombus formation or embolization. Similar to surgical ligation of the left atrial appendage, Lariat ligation is limited by leaks in a small percentage of patients...
October 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29250245/ashman-phenomenon-dynamicity-during-atrial-fibrillation-the-critical-role-of-the-long-cycles
#18
Damián Longo, Adrian Baranchuk
A case of a patient with Atrial Fibrillation and intermittent wide complex beats. What's the mechanism?
October 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29250244/atrioesophageal-fistula-after-atrial-fibrillation-ablation-a-single-center-series
#19
Houman Khakpour, Richard J Shemin, Jay M Lee, Eric Buch, Noel G Boyle, Kalyanam Shivkumar, Jason S Bradfield
Background: The incidence of atrioesophageal fistula (AEF) after atrial fibrillation catheter ablation is reported to be 0.015%-0.04%, though it is likely underreported due to a number of factors including misdiagnosis. We report our institutional experience with AEF. Methods: Patients with confirmed diagnosis of AEF between 2004 and 2016 at our institution were identified (n=5) and their clinical characteristics and outcome were analyzed. Results: AEF occurred in 5 patients who underwent AF catheter ablation (3 ablated at our institution; 2 transferred from outside hospitals after diagnosis of AEF)...
October 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29250243/efficacy-of-catheter-ablation-and-concomitant-antiarrhythmic-drugs-on-the-reduction-of-the-arrhythmia-burden-in-patients-with-long-standing-persistent-atrial-fibrillation
#20
Atsuhiko Yagishita, Yasuteru Yamauchi, Hironori Sato, Shu Yamashita, Tatsuhiko Hirao, Takamichi Miyamoto, Kenzo Hirao
Background: Little is known about the long-term outcome and recurrent form recurrence after catheter ablation of atrial fibrillation (AF) in patients with long-standing persistent AF. Methods: Two hundred thirty-six patients with persistent AF (193 men; age, 61.5±10.7 years) were enrolled, and were classified according to the duration of AF: AF duration of <1 year (group A, n=99), between 1 to 5 years (group B, n=101), and ≥5 years (group C, n=36). The long-term recurrence rate and recurrent form were compared among the groups...
October 2017: Journal of Atrial Fibrillation
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