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Journal of Atrial Fibrillation

Karam Ayoub, Fuad Habash, Ahmed Almomani, Jack Xu, Meera Marji, Allison Shaw-Devine, Hakan Paydak, Srikanth Vallurupalli
Background: New onset post-operative atrial fibrillation (POAF) can complicate both non-cardiac(NCS) and cardiac(CS) surgeries. Long term differences in recurrence of atrial fibrillation (AF) and incidence of ischemic stroke/transient ischemic attack(CVA)between these types of POAFare lacking. Objective: To compare thelong term recurrence rate of AF and incidence of CVAin patients withnew onset POAF after CS and NCS. Methods: All patients who developed POAF between May 2010 and April 2014 were included in this single-center, retrospective study Exclusion criteria included a prior history of atrial tachyarrhythmias and pre-operative use of anti-arrhythmic drugs...
April 2018: Journal of Atrial Fibrillation
Dimitrios Varvarousis, Nikolaos Goulas, Kali Polytarchou, Stavroula N Psychari, Konstantinos Paravolidakis, Agapi Konstantinidou, Dionysios Tsoukalas, Delia Vlad, Konstantina Bouki, Athanasios Kotsakis
Background: Permanent pacemaker implantation is accompanied by minor myocardial damage, indicated by elevated serum levels of cardiac biomarkers. Aim of this prospective study was to comparably investigate the lead fixation type effect on the extent of myocardial injury and inflammation following pacemaker implantation, and to assess the possible clinical implications. Methods: Cardiac troponin I (cTnI) and C-reactive protein (CRP) were measured at baseline, 6 and 24h after implantation in 101 patients, categorized into the active and passive lead fixation group...
April 2018: Journal of Atrial Fibrillation
Philippe Maury, Anne Rollin, Cristelle Cardin, Pierre Mondoly, Fernando Guerrero
While ablation of accessory pathways is usually performed without 3D mapping system, we present a case where high-density mapping helps in illustrating the anatomical features of epicardial and oblique AP connections.
April 2018: Journal of Atrial Fibrillation
Mark Hensey, Louisa O'Neill, Ciara Mahon, Stephen Keane, Aurelie Fabre, David Keane
The left atrial appendage (LAA) has a key role in the embolic complications of atrial fibrillation (AF). It has been studied extensively, from recent interest in the thrombotic implications of various LAA morphologies to LAA occlusion and ablation. We collected eleven post-mortem LAA samples for visual analysis, two were not included due to poor sample quality. On examination of the nine remaining samples, several common patterns of pectinate muscle orientation were noted. The LAA samples were noted to have a smooth circumferential neck of muscular tissue giving rise to a dominant singular smooth trunk of papillary muscle in 6 cases and two trunks in 3 cases...
April 2018: Journal of Atrial Fibrillation
Pattara Rattanawong, Jirat Chenbhanich, Wasawat Vutthikraivit, Pakawat Chongsathidkiet
Background: Recent studies suggested that variants on chromosome loci 4q25, 1q21, and 16q22 were associated with atrial fibrillation recurrence after catheter ablation. In this study, we performed a systematic review and meta-analysis to explore the association between variants on chromosome loci 4q25, 1q21, and 16q22 and atrial fibrillation recurrence after catheter ablation. Methods: We comprehensively searched the databases of MEDLINE and EMBASE from inception to January 2017...
April 2018: Journal of Atrial Fibrillation
Zardasht Oqab, Payam Pournazari, Robert S Sheldon
Background: Atrial fibrillation (AF) and frailty are both associated with advanced age. Oral anticoagulants (OAC) effectively prevent strokes in AF patients but are underutilized in the elderly, possibly due to misperception of frailty. Objective: We performed a systematic review to determine the prevalence of frailty in patients with AF, and whether frailty was associated with reduced prescription of OAC. Methods: We systematically searched Cochrane, MEDLINE, EMBASE, and PubMed databases...
April 2018: Journal of Atrial Fibrillation
Bassareo Pp, Namana V, Puddu M, Marras S, Fanos V, Mercuro G
Introduction: Recent published data demonstrated how subjects born preterm are at higher risk of developing early atrial fibrillation (AF). Materials and Methods: The surface ECG of twenty-four adults, former preterm infants born with an extremely low birth weight (ex-ELBW; mean age at study: 23.2±3.3 years; mean gestational age: 27.8±2.3 weeks; mean birth weight: 840±120.1 grams), were compared with those of 24 healthy counterparts born at term (C). A few parameters known to be capable of predicting a predisposition to develop AF were examined: P wave duration and dispersion, P terminal force, isoelectric interval length, PR interval length, and advanced interatrial blocks...
April 2018: Journal of Atrial Fibrillation
Oscar Westin, Line Jee Hartmann Rasmussen, Ove Andersen, Eric Buch, Jesper Eugen- Olsen, Jens Friberg
Soluble urokinase plasminogen activator receptor (suPAR) is a biomarker of chronic low-grade inflammation and a potent predictor of cardiovascular events. We hypothesized that plasma suPAR levels would predict new-onset atrial fibrillation (AF) in a large cohort of con-secutively admitted acute medical patients during long-term follow-up. In 14,764 acutely ad-mitted patients without prior or current AF, median suPAR measured upon admission was 2.7 ng/ml (interquartile range (IQR) 1.9-4.0). During a median follow-up of 392 days (IQR 218-577), 349 patients (2...
April 2018: Journal of Atrial Fibrillation
Martin Borlich, Leon Iden, Krister Kuhnhardt, Ingo Paetsch, Gerhard Hindricks, Philipp Sommer
Catheter ablation of atrial fibrillation has evolved enormously thanks to rapid improvement of modern mapping technologies, progress in catheter development and current possibilities for reduction of radiation exposure. Pulmonary vein isolation is thereby the cornerstone in this interventional treatment. Increased precision of catheter localization by modern three-dimensional mapping systems, faster and better processing of local electrograms and their immediate color-based visualization make it possible to treat even challenging arrhythmias very effectively...
April 2018: Journal of Atrial Fibrillation
Luca De Mattia, Martino Crosato, Stefano Indiani, Elena Causin, Claudia Licciardello, Paolo Antonio Maria Squasi, Alessandro De Leo, Vittorio Calzolari
Introduction: Pulmonary vein isolation (PVI) using contact force (CF) sensing ablation catheters currently relies on CF and force-time integral (FTI) guidelines. Such measurement of lesion effectiveness still lacks information on current delivery to the tissue, influenced by system impedance and power. Lesion Index (LSI) is a multi-parametric index incorporating CF and radiofrequency current data across time. We aimed to prospectively assess the efficacy of an LSI-guided approach to PVI in patients with paroxysmal atrial fibrillation (PAF)...
April 2018: Journal of Atrial Fibrillation
Francesca Salghetti, Juan-Pablo Abugattas, Valentina De Regibus, Saverio Iacopino, Ken Takarada, Erwin Ströker, Hugo-Enrique Coutiño, Ian Lusoc, Juan Sieira, Lucio Capulzini, Giacomo Mugnai, Vincent Umbrain, Stefan Beckers, Pedro Brugada, Carlo de Asmundis, Gian-Battista Chierchia
Aims: Real Time Recordings (RTR) of pulmonary vein (PV) activity provide important information in the setting of the 2nd generation Cryoballoon (CB-A), as a funcion of time to isolation. Visualization of RTR with the standard inner lumen mapping catheter (ILMC) 20mm Achieve (AC) is possible in roughly 50% of PVs. A novel 25mm-Achieve Advance (AC-A) has been developed with the aim of increasing the detection of RTR. The purpose of this study is to compare the AC-A with the AC, to feasibility and improvement of RTR...
April 2018: Journal of Atrial Fibrillation
Andres Enriquez, Javad Hashemi, Kevin Michael, Hoshiar Abdollah, Christopher Simpson, Adrian Baranchuk, Damian Redfearn
Purpose: Catheter ablation is an effective therapy for symptomatic atrial fibrillation (AF). The aim of this study was to assess the effect of ibutilide administration in patients with long standing persistent AF undergoing catheter ablation. Methods: We included 25 patients undergoing stepwise catheter ablation with ibutilide 1.0 mg infused prior to mapping and ablation as first step. Procedural and long-term outcomes were compared to a matched cohort of 25 patients in which ibutilide was not used but all other steps remained the same...
April 2018: Journal of Atrial Fibrillation
Tawseef Dar, Bharath Yarlagadda, Cheen Alkhatib, Dhanunjaya Lakkireddy
Catheter Radiofrequency ablation (RFA) for the management of atrial fibrillation (AF) can be associated with serious thermal injuries of the esophagus due to the close proximity of later. Use of Esophageal/Rectal temperature monitoring probes have become a standard practice now during these procedures in order to prevent such complications. However these probes need small introducer sheaths in order to guide them into the esophagus without coiling. Due to the small size of these sheaths, they can easily get dislodged into the trachea or esophagus and cause serious complications including mucosal lacerations...
February 2018: Journal of Atrial Fibrillation
Tolga Aksu, Tumer Erdem Guler, Serdar Bozyel, Kivanc Yalin, Ferit Onur Mutluer
The effects of cryoballoon (CB) ablation in non-pulmonary vein sites have not clearly elucidated. Herein we present a new definition method which helps to predict autonomic modification effect of CB application using atrial electrogram (EGM) characteristics and vagal responses (VRs). A 54-year-old man underwent pulmonary vein isolation (PVI) for paroxysmal atrial fibrillation. Both atria were mapped with the aid of electroanatomical mapping system prior to ablation procedure. The atrial EGMs were divided into 3 groups according to duration, amplitude, and number of deflections...
February 2018: Journal of Atrial Fibrillation
Gianluca Rigatelli, Marco Zuin, Alan Fong
Background: An impairment of the left atrial function similar to that usually observed in atrial fibrillation (AF) has been observed also in patients with patent foramen ovale (PFO) and permanent right-to-left shunting (RLS). Methods: We reconstructed the geometrical model of right atrium (RA), PFO, left atrium (LA) and left atrial appendage (LAA) of 65 patients with mild (36 patients mean age 45.5±6.8 years, 24 females) or permanent (29 patients, mean age 45.1±5...
February 2018: Journal of Atrial Fibrillation
George Louridas, Katerina Lourida
No abstract text is available yet for this article.
February 2018: Journal of Atrial Fibrillation
John J Squiers, James R Edgerton
Occlusion of the left atrial appendage (LAA) may protect against stroke in patients with atrial fibrillation. While percutaneous LAA closure devices have demonstrated efficacy in stroke reduction, surgical LAA occlusion has been performed with mixed results to date. Although surgical exclusion via internal sutures or noncutting stapler is ineffective due to recanalization of the LAA, surgical excision and certain exclusion devices including the AtriClip device are effective methods to achieve complete closure of the LAA...
February 2018: Journal of Atrial Fibrillation
Kyoichiro Yazaki, Masahiro Watarai, Kenji Enta, Mitsuru Kahata, Asako Kumagai, Koji Inoue, Hiroshi Koganei, Masato Otsuka, Yasuhiro Ishii
Introduction: The efficacy of thoracic vein isolation (TVI), an approach to trigger atrial fibrillation (AF), for the management of AF has been established. Our goal was to identify the predictors for late recurrence of atrial tachyarrhythmias (ATAs), for which the patients and procedural and/or echocardiographic parameters were retrospectively analyzed. Although substrate modification in the atrium for the treatment of AF ablation remains controversial, the background associated with the outcome has not been fully investigated...
February 2018: Journal of Atrial Fibrillation
Tolga Aksu, Tumer Erdem Guler, Serdar Bozyel, Kivanc Yalin
A 30-year-old man underwent ganglionated plexi ablation due to cardioinhibitory type vasovagal syncope with asystole. After asymptomatic period of 15-month following the procedure, the patient experienced 2 new syncope episodes. Tilt test demonstrated vasodepressor response without significant bradycardia. Following the onset of midodrine therapy, the patient was asymptomatic for 1 year and tilt test demonstrate normal response.
February 2018: Journal of Atrial Fibrillation
Mustafa Yildiz, Hulya Yilmaz Ak, Dogac Oksen, Sinan Oral
Many clinical challenges have been encountered in electrophysiology laboratories (EP) while implanting intracardiac defibrillators for lethal arrhythmias, using pacemakers for bradyarrhythmias, placing pacemakers with multiple leads in patients with heart failure and cardiac ablation procedures. In this environment, anesthesiology plays a very critical role to ensure patients comfort, as well as maintains operator's convenience and facilitate management of undesired situations. EP laboratories are mostly used for diagnosis of certain heart diseases...
February 2018: Journal of Atrial Fibrillation
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