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Cancer Epidemiology

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https://www.readbyqxmd.com/read/28528292/cancer-incidence-in-the-western-australian-mining-industry-1996-2013
#1
Nita Sodhi-Berry, Alison Reid, Lin Fritschi, Aw Bill Musk, Roel Vermeulen, Nicholas de Klerk, Susan Peters
BACKGROUND: Miners are frequently exposed to established and potential carcinogens. We aimed to assess cancer incidence in miners relative to the general population and identify high-risk subgroups. METHODS: Incident cancers in Western Australian miners (n=153,922; 86% male) during 1996-2013 were identified. Indirectly standardised incidence ratios (SIRs) were calculated and mixed-effects Poisson models were used to calculate Incidence Rate Ratios (IRRs) to identify high-risk within-cohort subgroups...
May 18, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28528291/the-association-of-lifetime-physical-inactivity-with-bladder-and-renal-cancer-risk-a-hospital-based-case-control-analysis
#2
Rikki Cannioto, John Lewis Etter, Lauren Beryl Guterman, Janine M Joseph, Nicholas R Gulati, Kristina L Schmitt, Michael J LaMonte, Ryan Nagy, Albina Minlikeeva, James Brian Szender, Kirsten B Moysich
OBJECTIVES: Recreational physical inactivity has been gaining recognition as an independent epidemiological exposure of interest in relation to cancer endpoints due to evidence suggesting that it may associate with cancer independent of obesity. In the current analyses, we examined the associations of lifetime recreational physical inactivity with renal and bladder cancer risk. METHODS: In this hospital-based case-control study, we identified N=160 renal cancer patients, N=208 bladder cancer patients, and N=766 age frequency-matched controls without cancer...
May 18, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28528290/modelling-lung-cancer-mortality-rates-from-smoking-prevalence-fill-in-the-gap
#3
Juan Carlos Martín-Sánchez, Usama Bilal, Ramon Clèries, Cristina Lidón-Moyano, Marcela Fu, Luís González-de Paz, Manuel Franco, Esteve Fernandez, Jose M Martínez-Sánchez
BACKGROUND: The objective of this study is to estimate the gap between smoking prevalence and lung cancer mortality and provide predictions of lung cancer mortality based on previous smoking prevalence. MATERIALS AND METHODS: We used data from the Spanish National Health Surveys (2003, 2006 and 2011) to obtain information about tobacco use and data from the Spanish National Statistics Institute to obtain cancer mortality rates from 1980 to 2013. We calculated the cross-correlation among the historical series of smoking prevalence and lung cancer mortality rate (LCMR) to estimate the most likely time gap between both series...
May 18, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28521283/reproductive-factors-exogenous-hormone-use-and-risk-of-pancreatic-cancer-in-postmenopausal-women
#4
Geoffrey C Kabat, Victor Kamensky, Thomas E Rohan
INTRODUCTION: The epidemiologic literature on menstrual and reproductive factors associated with pancreatic cancer has yielded weak and inconsistent evidence of an association. Furthermore, few cohort studies have examined the association of exogenous hormone use, including type and duration, with this disease. The aim of this study was to assess the association of these exposures with risk of pancreatic cancer in a large cohort of postmenopausal women. METHODS: We used data from the Women's Health Initiative on 1003 cases of pancreatic cancer diagnosed among 158,298 participants over 14...
May 15, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28511150/disparities-in-cancer-stage-at-diagnosis-and-survival-of-aboriginal-and-non-aboriginal-south-australians
#5
David Banham, David Roder, Dorothy Keefe, Gelareh Farshid, Marion Eckert, Margaret Cargo, Alex Brown
BACKGROUND/AIM: This study tested the utility of retrospectively staging cancer registry data for comparing stage and stage-specific survivals of Aboriginal and non-Aboriginal people. Differences by area level factors were also explored. METHODS: This test dataset comprised 950 Aboriginal cases and all other cases recorded on the South Australian cancer registry with a 1977-2010 diagnosis. A sub-set of 777 Aboriginal cases diagnosed in 1990-2010 were matched with randomly selected non-Aboriginal cases by year of birth, diagnostic year, sex, and primary site of cancer...
May 13, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28486205/statin-use-after-esophageal-cancer-diagnosis-and-survival-a-population-based-cohort-study
#6
Chris R Cardwell, Andrew D Spence, Carmel M Hughes, Liam J Murray
BACKGROUND: A recent epidemiological study of esophageal cancer patients concluded statin use post-diagnosis was associated with large (38%) and significant reductions in cancer-specific mortality. We investigated statin use and cancer-specific mortality in a large population-based cohort of esophageal cancer patients. METHODS: Newly diagnosed [2009-2012] esophageal cancer patients were identified from the Scottish Cancer Registry and linked with the Prescribing Information System and Scotland Death Records (to January 2015)...
May 6, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28482191/contextual-determinants-of-participation-in-cervical-cancer-screening-in-france-2010
#7
Mélanie Araujo, Jeanna-Eve Franck, Emmanuelle Cadot, Arnaud Gautier, Pierre Chauvin, Laurent Rigal, Virginie Ringa, Gwenn Menvielle
BACKGROUND: Some contextual factors associated with participation in cervical cancer screening are reported in the literature, but few studies have examined their combined effect. Our objective was to assess the role of contextual characteristics, separately and in combination, in participation in cervical cancer screening in France. METHODS: Marginal Poisson regression models - taking into account the correlation between women in a given commune - were conducted using data from the Baromètre Santé 2010 survey...
May 5, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28478931/sun-exposure-and-skin-cancer-and-the-puzzle-of-cutaneous-melanoma-a-perspective-on-fears-et-al-mathematical-models-of-age-and-ultraviolet-effects-on-the-incidence-of-skin-cancer-among-whites-in-the-united-states-american-journal-of-epidemiology-1977-105-420
#8
REVIEW
Bruce K Armstrong, Anne E Cust
Sunlight has been known as an important cause of skin cancer since around the turn of the 20th Century. A 1977 landmark paper of US scientists Fears, Scotto, and Schneiderman advanced a novel hypothesis whereby cutaneous melanoma was primarily caused by intermittent sun exposure (i.e. periodic, brief episodes of exposure to high-intensity ultraviolet radiation) while the keratinocyte cancers, squamous cell carcinoma and basal cell carcinoma, were primarily caused by progressive accumulation of sun exposure...
May 3, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28463808/no-outcome-disparities-in-patients-with-diffuse-large-b-cell-lymphoma-and-a-low-socioeconomic-status
#9
Karin Boslooper, Mels Hoogendoorn, Eric N van Roon, Robby E Kibbelaar, Huib Storm, Sjoerd Hovenga, Gerhard Woolthuis, Bas P van Rees, Bart Klijs, Nic J G M Veeger, Hanneke C Kluin-Nelemans, Geertruida H de Bock
INTRODUCTION: In patients with diffuse large B-cell lymphoma (DLBCL) socioeconomic status (SES) is associated with outcome in several population-based studies. The aim of this study was to further investigate the existence of disparities in treatment and survival. METHODS: A population-based cohort study was performed including 343 consecutive patients with DLBCL, diagnosed between 2005 and 2012, in the North-west of the Netherlands. SES was based on the socioeconomic position within the Netherlands by use of postal code and categorized as low, intermediate or high...
April 29, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28460349/nonalcoholic-fatty-liver-disease-and-mortality-among-cancer-survivors
#10
Justin C Brown, Michael O Harhay, Meera N Harhay
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) may foster a tumor microenvironment that promotes cancer recurrence and progression. We examined the relationship between NAFLD and mortality among a sample of cancer survivors. METHODS: Ultrasonography was used to assess hepatic steatosis, and standardized algorithms were used to define NAFLD. Study endpoints included all-cause, cancer-specific, and cardiovascular-specific mortality. RESULTS: Among 387 cancer survivors, 17...
April 28, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28456092/occupation-and-risk-of-prostate-cancer-in-canadian-men-a-case-control-study-across-eight-canadian-provinces
#11
Jeavana Sritharan, Paul A Demers, Shelley A Harris, Donald C Cole, Cheryl E Peters
BACKGROUND: The etiology of prostate cancer continues to be poorly understood, including the role of occupation. Past Canadian studies have not been able to thoroughly examine prostate cancer by occupation with detailed information on individual level factors. METHODS: Occupation, industry and prostate cancer were examined using data from the National Enhanced Cancer Surveillance System, a large population-based case-control study conducted across eight Canadian provinces from 1994 to 1997...
April 26, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28437692/stage-iv-colorectal-cancer-primary-site-and-patterns-of-distant-metastasis
#12
Jamaica R Robinson, Polly A Newcomb, Sheetal Hardikar, Stacey A Cohen, Amanda I Phipps
BACKGROUND: Although colorectal cancer (CRC) usually metastasizes to the liver and/or lungs, factors influencing the anatomic pattern of metastases remain poorly understood. METHODS: We assessed the relationship between primary CRC site and pattern of synchronous metastasis among 1202 individuals diagnosed with incident metastatic CRC between 2010 and 2014 and identified through the Seattle-Puget Sound Surveillance, Epidemiology, and End Results (SEER) registry...
April 21, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28426981/overall-survival-in-elderly-patients-with-colorectal-cancer-a-population-based-study-in-the-caribbean
#13
Clarisse Joachim, Lidvine Godaert, Moustapha Dramé, Jacqueline Véronique-Baudin, Jonathan Macni, Juliette Smith-Ravin, Jean-Luc Novella, Rachid Mahmoudi
BACKGROUND: Population-based Cancer registries (PBCR) play an important role in cancer surveillance and research. The aim of this study was to examine overall survival in elderly patients with colorectal cancer (CRC) by analysing data from the Martinique PBCR between 1993 and 2012. METHODS: The log-rank test was used to assess the statistical differences of the survival curves by each categorical variable: age at diagnosis, sex, histology, zone of residence, subsite, stage at diagnosis, and chemotherapy...
April 17, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28426980/hormonal-and-reproductive-risk-factors-of-papillary-thyroid-cancer-a-population-based-case-control-study-in-france
#14
Emilie Cordina-Duverger, Christophe Leux, Monica Neri, Catherine Tcheandjieu, Anne-Valérie Guizard, Claire Schvartz, Thérèse Truong, Pascal Guénel
The three times higher incidence of thyroid cancer in women compared to men points to a role of female sex hormones in its etiology. However the effects of these factors are poorly understood. We analyzed the association between thyroid cancer and hormonal and reproductive factors among women enrolled in CATHY, a population-based case-control study conducted in France. The study included 430 cases of papillary thyroid cancer and 505 controls frequency-matched on age and area of residence. The odds ratios for thyroid cancer increased with age at menarche (p trend 0...
April 17, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28419901/does-exclusion-of-cancers-registered-only-from-death-certificate-information-diminish-socio-demographic-disparities-in-recorded-survival
#15
Hanna E Tervonen, David Roder, Stephen Morrell, Hui You, David C Currow
BACKGROUND: Death Certificate Only (DCO) cancer cases are commonly excluded from survival analyses due to unknown survival time. This study examines whether socio-demographic factors are associated with DCO diagnosis, and the potential effects of excluding DCO cases on socio-demographic cancer survival disparities in NSW, Australia. METHODS: NSW Cancer Registry data for cases diagnosed in 2000-2008 were used in this study. Logistic regression was used to estimate the odds of DCO registration by socio-demographic sub-group (socio-economic disadvantage, residential remoteness, country of birth, age at diagnosis)...
April 15, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28412477/impact-of-major-life-events-on-breast-cancer-specific-mortality-a-case-fatality-study-on-8000-breast-cancer-patients
#16
Sanna Heikkinen, Joonas Miettinen, Eero Pukkala, Markku Koskenvuo, Nea Malila, Janne Pitkäniemi
BACKGROUND: It has been suggested that long-term activation of the body's stress-response system and subsequent overexposure to stress hormones may be associated with increased morbidity. However, evidence on the impact of major life events on mortality from breast cancer (BC) remains inconclusive. The main aim of this study is to investigate whether major negatively or positively experienced life events before or after diagnosis have an effect on BC-specific mortality in women who have survived with BC for at least 2 years...
April 14, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28371729/impact-of-adjuvant-chemotherapy-on-survival-of-women-with-t1n0m0-hormone-receptor-negative-breast-cancer
#17
Nanthini Thevi Bhoo-Pathy, Shinako Inaida, Shiro Tanaka, Nur Aishah Taib, Cheng-Har Yip, Marniza Saad, Koji Kawakami, Nirmala Bhoo-Pathy
BACKGROUND: The benefit of adjuvant chemotherapy in women with T1N0M0 breast cancers is unclear. While gene expression-based prognostic assays may aid management of women with early estrogen receptor (ER) positive tumors, therapeutic decision-making in women with early stage ER negative tumors remains fraught with difficulties. We investigated the association between adjuvant chemotherapy and overall survival in women with T1N0M0, hormone receptor negative breast cancers. METHOD: All newly diagnosed breast cancer patients with node-negative and hormone receptor negative tumors measuring≤2cm at the University Malaya Medical Centre (Malaysia) from 1993 to 2013 were included...
March 31, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28365446/comorbidity-trajectories-in-working-age-cancer-survivors-a-national-study-of-swedish-men
#18
Ayako Hiyoshi, Katja Fall, Cecilia Bergh, Scott Montgomery
BACKGROUND: A large proportion of cancer survivors are of working age, and maintaining health is of interest both for their working and private life. However, patterns and determinants of comorbidity over time among adult cancer survivors are incompletely described. We aimed to identify distinct comorbidity trajectories and their potential determinants. METHODS: In a cohort study of Swedish men born between 1952 and 1956, men diagnosed with cancer between 2000 and 2003 (n=878) were matched with cancer-free men (n=4340) and followed over five years after their first year of survival...
March 30, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28364671/social-disparities-in-survival-after-diagnosis-with-colorectal-cancer-contribution-of-race-and-insurance-status
#19
Dianne Pulte, Lina Jansen, Hermann Brenner
BACKGROUND: Both minority race and lack of health insurance are risk factors for lower survival in colorectal cancer (CRC) but the interaction between the two factors has not been explored in detail. METHODS: One to 5-year survival by race/ethnic group and insurance type for patients with CRC diagnosed in 2007-13 and registered in the Surveillance Epidemiology, and End RESULTS: database were explored. Shared frailty models were computed to further explore the association between CRC specific survival and insurance status after adjustment for demographic and treatment variables...
March 29, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28364670/alcohol-consumption-and-risk-of-upper-tract-urothelial-cancer
#20
Masayoshi Zaitsu, Ichiro Kawachi, Takumi Takeuchi, Yasuki Kobayashi
BACKGROUND: Upper-tract urothelial cancer (UTUC), which includes renal pelvic cancer and ureter cancer, is a rare cancer and its prognosis is poor. Smoking and high-risk occupations (e.g., printing and dyestuff working which involves exposure to aniline dyes) are well-known risk factors for UTUC. However, the risk of alcohol consumption in UTUC remains unclear. This study aimed to determine whether alcohol consumption is an independent risk factor for UTUC. METHODS: The study was a case-control study which used the nationwide clinical inpatient database of the Rosai Hospital group in Japan...
March 29, 2017: Cancer Epidemiology
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