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Cancer Epidemiology

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https://www.readbyqxmd.com/read/28426981/overall-survival-in-elderly-patients-with-colorectal-cancer-a-population-based-study-in-the-caribbean
#1
Clarisse Joachim, Lidvine Godaert, Moustapha Dramé, Jacqueline Véronique-Baudin, Jonathan Macni, Juliette Smith-Ravin, Jean-Luc Novella, Rachid Mahmoudi
BACKGROUND: Population-based Cancer registries (PBCR) play an important role in cancer surveillance and research. The aim of this study was to examine overall survival in elderly patients with colorectal cancer (CRC) by analysing data from the Martinique PBCR between 1993 and 2012. METHODS: The log-rank test was used to assess the statistical differences of the survival curves by each categorical variable: age at diagnosis, sex, histology, zone of residence, subsite, stage at diagnosis, and chemotherapy...
April 17, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28426980/hormonal-and-reproductive-risk-factors-of-papillary-thyroid-cancer-a-population-based-case-control-study-in-france
#2
Emilie Cordina-Duverger, Christophe Leux, Monica Neri, Catherine Tcheandjieu, Anne-Valérie Guizard, Claire Schvartz, Thérèse Truong, Pascal Guénel
The three times higher incidence of thyroid cancer in women compared to men points to a role of female sex hormones in its etiology. However the effects of these factors are poorly understood. We analyzed the association between thyroid cancer and hormonal and reproductive factors among women enrolled in CATHY, a population-based case-control study conducted in France. The study included 430 cases of papillary thyroid cancer and 505 controls frequency-matched on age and area of residence. The odds ratios for thyroid cancer increased with age at menarche (p trend 0...
April 17, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28419901/does-exclusion-of-cancers-registered-only-from-death-certificate-information-diminish-socio-demographic-disparities-in-recorded-survival
#3
Hanna E Tervonen, David Roder, Stephen Morrell, Hui You, David C Currow
BACKGROUND: Death Certificate Only (DCO) cancer cases are commonly excluded from survival analyses due to unknown survival time. This study examines whether socio-demographic factors are associated with DCO diagnosis, and the potential effects of excluding DCO cases on socio-demographic cancer survival disparities in NSW, Australia. METHODS: NSW Cancer Registry data for cases diagnosed in 2000-2008 were used in this study. Logistic regression was used to estimate the odds of DCO registration by socio-demographic sub-group (socio-economic disadvantage, residential remoteness, country of birth, age at diagnosis)...
April 15, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28412477/impact-of-major-life-events-on-breast-cancer-specific-mortality-a-case-fatality-study-on-8000-breast-cancer-patients
#4
Sanna Heikkinen, Joonas Miettinen, Eero Pukkala, Markku Koskenvuo, Nea Malila, Janne Pitkäniemi
BACKGROUND: It has been suggested that long-term activation of the body's stress-response system and subsequent overexposure to stress hormones may be associated with increased morbidity. However, evidence on the impact of major life events on mortality from breast cancer (BC) remains inconclusive. The main aim of this study is to investigate whether major negatively or positively experienced life events before or after diagnosis have an effect on BC-specific mortality in women who have survived with BC for at least 2 years...
April 13, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28371729/impact-of-adjuvant-chemotherapy-on-survival-of-women-with-t1n0m0-hormone-receptor-negative-breast-cancer
#5
Nanthini Thevi Bhoo-Pathy, Shinako Inaida, Shiro Tanaka, Nur Aishah Taib, Cheng-Har Yip, Marniza Saad, Koji Kawakami, Nirmala Bhoo-Pathy
BACKGROUND: The benefit of adjuvant chemotherapy in women with T1N0M0 breast cancers is unclear. While gene expression-based prognostic assays may aid management of women with early estrogen receptor (ER) positive tumors, therapeutic decision-making in women with early stage ER negative tumors remains fraught with difficulties. We investigated the association between adjuvant chemotherapy and overall survival in women with T1N0M0, hormone receptor negative breast cancers. METHOD: All newly diagnosed breast cancer patients with node-negative and hormone receptor negative tumors measuring≤2cm at the University Malaya Medical Centre (Malaysia) from 1993 to 2013 were included...
March 31, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28365446/comorbidity-trajectories-in-working-age-cancer-survivors-a-national-study-of-swedish-men
#6
Ayako Hiyoshi, Katja Fall, Cecilia Bergh, Scott Montgomery
BACKGROUND: A large proportion of cancer survivors are of working age, and maintaining health is of interest both for their working and private life. However, patterns and determinants of comorbidity over time among adult cancer survivors are incompletely described. We aimed to identify distinct comorbidity trajectories and their potential determinants. METHODS: In a cohort study of Swedish men born between 1952 and 1956, men diagnosed with cancer between 2000 and 2003 (n=878) were matched with cancer-free men (n=4340) and followed over five years after their first year of survival...
March 30, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28364671/social-disparities-in-survival-after-diagnosis-with-colorectal-cancer-contribution-of-race-and-insurance-status
#7
Dianne Pulte, Lina Jansen, Hermann Brenner
BACKGROUND: Both minority race and lack of health insurance are risk factors for lower survival in colorectal cancer (CRC) but the interaction between the two factors has not been explored in detail. METHODS: One to 5-year survival by race/ethnic group and insurance type for patients with CRC diagnosed in 2007-13 and registered in the Surveillance Epidemiology, and End RESULTS: database were explored. Shared frailty models were computed to further explore the association between CRC specific survival and insurance status after adjustment for demographic and treatment variables...
March 29, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28364670/alcohol-consumption-and-risk-of-upper-tract-urothelial-cancer
#8
Masayoshi Zaitsu, Ichiro Kawachi, Takumi Takeuchi, Yasuki Kobayashi
BACKGROUND: Upper-tract urothelial cancer (UTUC), which includes renal pelvic cancer and ureter cancer, is a rare cancer and its prognosis is poor. Smoking and high-risk occupations (e.g., printing and dyestuff working which involves exposure to aniline dyes) are well-known risk factors for UTUC. However, the risk of alcohol consumption in UTUC remains unclear. This study aimed to determine whether alcohol consumption is an independent risk factor for UTUC. METHODS: The study was a case-control study which used the nationwide clinical inpatient database of the Rosai Hospital group in Japan...
March 29, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28363161/family-history-of-cancer-and-the-risk-of-bladder-cancer-a-case-control-study-from-italy
#9
Federica Turati, Cristina Bosetti, Jerry Polesel, Diego Serraino, Maurizio Montella, Massimo Libra, Gaetano Facchini, Monica Ferraroni, Alessandra Tavani, Carlo La Vecchia, Eva Negri
BACKGROUND: A family history of bladder cancer has been associated with the risk of bladder cancer, but quantification of the excess risk in different populations is still a relevant issue. Further, the role of a family history of other cancers on the risk of bladder cancer remains unclear. METHODS: We analyzed data from an Italian case-control study, including 690 bladder cancer cases and 665 hospital controls. Odds ratios (ORs) were estimated through unconditional logistic regression models, adjusted for sex, age, study center, year of interview and further for education, smoking and sibling's number...
March 28, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28319725/antiestrogen-use-in-breast-cancer-patients-reduces-the-risk-of-subsequent-lung-cancer-a-population-based-study
#10
Sung-Chao Chu, Chia-Jung Hsieh, Tso-Fu Wang, Mun-Kun Hong, Tang-Yuan Chu
BACKGROUND: There is accumulating epidemiological and preclinical evidence that estrogen might be a driver of lung cancer. Breast cancer survivors can offer a unique patient cohort to examine the effect of antiestrogen therapy on lung cancer carcinogenesis because many of these women would have received long-term selective estrogen receptor modulators (SERMs) and/or aromatase inhibitors (AIs) as adjuvant treatment. Our hypothesis is that estrogens play a role in lung cancer development, and that antiestrogen therapy would affect the incidence of subsequent lung cancer among breast cancer survivors...
March 17, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28315607/correcting-bias-due-to-missing-stage-data-in-the-non-parametric-estimation-of-stage-specific-net-survival-for-colorectal-cancer-using-multiple-imputation
#11
Milena Falcaro, James R Carpenter
BACKGROUND: Population-based net survival by tumour stage at diagnosis is a key measure in cancer surveillance. Unfortunately, data on tumour stage are often missing for a non-negligible proportion of patients and the mechanism giving rise to the missingness is usually anything but completely at random. In this setting, restricting analysis to the subset of complete records gives typically biased results. Multiple imputation is a promising practical approach to the issues raised by the missing data, but its use in conjunction with the Pohar-Perme method for estimating net survival has not been formally evaluated...
March 15, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28314172/the-risk-of-cancer-in-the-offspring-and-parental-length-of-life
#12
Ruby Del Risco Kollerud, Karl Gerhard Blaasaas, Bjørgulf Claussen, Bente Oftedal, Øyvind Næss
BACKGROUND: We investigated if cancer onset in offspring is related to having short-lived parents for different cancer types and to see if there was a difference in smoking- and non-smoking related cancers. METHODS: Our study included 524,391 individuals born in Norway 1940-1950. All children were followed up for cancer from the age of 20 until they were between 59 and 69 years. Parental longevity was examined by grouping parental age of death into parents dying before 75 years of age and parents dying at 75 years of age or older...
March 14, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28291679/low-dose-aspirin-use-and-survival-in-breast-cancer-patients-a-nationwide-cohort-study
#13
LETTER
Úna Mc Menamin, Chris Cardwell, Carmel Hughes, Liam Murray
No abstract text is available yet for this article.
March 10, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28282541/measures-of-economic-advantage-associated-with-hpv-positive-head-and-neck-cancers-among-non-hispanic-black-and-white-males-identified-through-the-national-cancer-database
#14
Caryn E Peterson, Shaveta Khosla, Gina D Jefferson, Faith G Davis, Marian L Fitzgibbon, Sally Freels, Timothy P Johnson, Kent Hoskins, Charlotte E Joslin
BACKGROUND: National trends show dramatic increases in the incidence of HPV-related head and neck squamous cell carcinomas (HNSCCs) among black and white males. Using cases identified through the National Cancer Data Base, we assessed factors associated with HPV 16- or 16/18 positive HNSCCs among non-Hispanic black and white males diagnosed in the U.S. between 2009 and 2013. METHODS: This sample included 21,524 HNSCCs with known HPV status. Adjusted relative risks (RRs) and 95% confidence intervals (CIs) were estimated using log-binomial regression...
March 7, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28274695/a-pathologist-s-perspective-on-thyroid-cancer-trends-in-thailand
#15
LETTER
Andrey Bychkov
No abstract text is available yet for this article.
March 5, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28268206/profile-of-cancer-in-the-eastern-mediterranean-region-the-need-for-action
#16
Ivana Kulhánová, Freddie Bray, Ibtihal Fadhil, Ali Saeed Al-Zahrani, Amani El-Basmy, Wagida A Anwar, Amal Al-Omari, Ali Shamseddine, Ariana Znaor, Isabelle Soerjomataram
BACKGROUND: Many countries in the Eastern Mediterranean region (EMR) are undergoing marked demographic and socioeconomic transitions that are increasing the cancer burden in region. We sought to examine the national cancer incidence and mortality profiles as a support to regional cancer control planning in the EMR. METHODS: GLOBOCAN 2012 data were used to estimate cancer incidence and mortality by country, cancer type, sex and age in 22 EMR countries. We calculated age-standardized incidence and mortality rates (per 100,000) using direct method of standardization...
March 4, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28268162/association-between-aspirin-use-triple-negative-breast-cancer-more-benefit-is-expected
#17
LETTER
Kadri Altundag
No abstract text is available yet for this article.
March 4, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28258029/incidence-trends-in-oesophageal-cancer-by-histological-type-an-updated-analysis-in-sweden
#18
Shao-Hua Xie, Fredrik Mattsson, Jesper Lagergren
BACKGROUND: We aimed to update incidence trends of oesophageal cancer by histological type in Sweden. METHODS: Using data from the Swedish Cancer Registry, we examined incidence trends of oesophageal cancer by histological types in individuals aged ≥50 years in 1970-2014 using log-linear joinpoint regressions. RESULTS: The age-standardised incidence rate of oesophageal adenocarcinoma in men increased on average by 3.0% per year in 1970-1994, followed by a more rapid increase of 13...
February 28, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28242577/risk-of-second-primary-cancer-associated-with-pre-diagnostic-smoking-alcohol-and-obesity-in-women-with-keratinocyte-carcinoma
#19
Sang Min Park, Tricia Li, Shaowei Wu, Wen-Qing Li, Abrar A Qureshi, Meir Stampfer, Eunyoung Cho
Keratinocyte carcinoma (KC), which includes basal-cell carcinoma (BCC) and squamous-cell cancer (SCC), has been associated with an increased risk of second primary cancers (SPCs), although the reason for this increase is unknown. We assessed the effects of smoking, alcohol, and obesity prior to the diagnosis of KC on the development of SPCs, as these are well-established risk factors for multiple cancers and may also contribute to the increased risk of SPCs among those with KC. A total of 15,628 women with self-reported KC were identified in the Nurses' Health Study...
February 24, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28236754/lymphohaematopoietic-malignancies-in-scottish-military-veterans-retrospective-cohort-study-of-57-000-veterans-and-173-000-non-veterans
#20
Beverly P Bergman, Daniel F Mackay, Jill P Pell
BACKGROUND: Lymphohaematopoietic malignancies are common in the general population. There have been concerns that military service may be associated with increased risk as a result of occupational exposures. To date, few studies have demonstrated an increased risk, although a disability pension is payable to veterans who were present at nuclear tests and who develop leukaemia (other than chronic lymphocytic leukaemia). The aim of the study was to utilise data from the Scottish Veterans Health Study to examine the risk of lymphohaematopoietic malignancy following military service in a large national cohort of veterans...
February 22, 2017: Cancer Epidemiology
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