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Cancer Epidemiology

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https://www.readbyqxmd.com/read/30015055/trends-in-the-incidence-of-primary-brain-central-nervous-system-and-intracranial-tumors-in-israel-1990-2015
#1
Lital Keinan-Boker, Eitan Friedman, Barbara G Silverman
BACKGROUND: The association between cellphone technology and brain, central nervous system (CNS) and intracranial tumors is unclear. Analysis of trends in incidence of such tumors for periods during which cellphone use increased dramatically may add relevant information. Herein we describe secular trends in the incidence of primary tumors of the brain and CNS from 1990 to 2015 in Israel, a period during which cellphone technology became extremely prevalent in Israel. METHODS: All cases of primary brain, CNS and intracranial tumors (excluding lymphomas) diagnosed in Israel from 1990 to 2015 were identified in the Israel National Cancer Registry database and categorized by behavior (malignant; benign/uncertain behavior) and histologic type...
July 13, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/30005388/transgenerational-effects-of-chemotherapy-both-male-and-female-children-born-to-women-exposed-to-chemotherapy-have-fewer-children
#2
Biren Patel, Huong Meeks, Yuan Wan, Erica B Johnstone, Martha Glenn, Ken R Smith, James M Hotaling
BACKGROUND: There is little known about the transgenerational effect of chemotherapy. For example, chemotherapy is known to decrease fecundity in women. But if women are able to have offspring after chemotherapy exposure, do these children also have decreased fecundity? METHODS: This study is a retrospective cohort study utilizing the Utah Population Database (UPDB), a comprehensive resource that links birth, medical, death and cancer records for individuals in the state of Utah...
July 10, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29990795/epidemiological-surveillance-of-mesothelioma-mortality-in-italy
#3
Lucia Fazzo, Giada Minelli, Marco De Santis, Caterina Bruno, Amerigo Zona, Susanna Conti, Pietro Comba
BACKGROUND: Malignant mesothelioma (MM) is causally linked to asbestos exposure with an estimated etiological fraction of 80% or more. METHODS: Standardized rates of all mesothelioma (C45, ICD-10) and malignant pleural mesothelioma (C45.0, ICD-10) mortality in Italy were computed at national and regional levels, for the period 2003-2014. Standardized Mortality Ratios (SMRs, with 95% Confidence Intervals) were calculated for each of the 8047 Italian municipalities, for both diseases, with respect to Regional figures...
July 7, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29990794/intake-of-folate-and-other-nutrients-related-to-one-carbon-metabolism-and-risk-of-cutaneous-melanoma-among-us-women-and-men
#4
Ashar Dhana, Hsi Yen, Tricia Li, Michelle D Holmes, Abrar A Qureshi, Eunyoung Cho
BACKGROUND: Nutrients involved in one-carbon metabolism - folate, vitamins B6 and B12, methionine, choline, and betaine - have been inversely associated with multiple cancer sites and may be related to skin cancer. However, there is a lack of research on the association between intake of these nutrients and cutaneous melanoma risk. The aim of this study was to examine the associations between intake of one-carbon metabolism nutrients and cutaneous melanoma risk in two large prospective cohorts...
July 7, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29986235/domperidone-use-and-risk-of-primary-liver-cancer-in-the-clinical-practice-research-datalink
#5
Jake E Thistle, Jessica L Petrick, Baiyu Yang, Marie C Bradley, Barry I Graubard, Katherine A McGlynn
BACKGROUND: Pronounced sex-disparity in liver cancer suggests a role for hormones, one of which could be prolactin. Stimulation of prolactin production in mice via domperidone has been reported to decrease hepatocarcinogenesis, thus may have chemopreventive potential. To study the effect of domperidone in humans, a large medical records study was conducted. METHODS: Based in the Clinical Practice Research Datalink, 1921 liver cancer cases and 7681 controls were identified...
July 6, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29980028/hormonal-contraceptive-use-and-smoking-as-risk-factors-for-high-grade-cervical-intraepithelial-neoplasia-in-unvaccinated-women-aged-30-44-years-a-case-control-study-in-new-south-wales-australia
#6
Huilan Xu, Sam Egger, Louiza S Velentzis, Dianne L O'Connell, Emily Banks, Jessica Darlington-Brown, Karen Canfell, Freddy Sitas
BACKGROUND: Human papillomavirus (HPV) vaccines protect against HPV types 16/18, but do not eliminate the need to detect pre-cancerous lesions. Australian women vaccinated as teenage girls are now entering their mid-thirties. Since other oncogenic HPV types have been shown to be more prevalent in women ≥30 years old, understanding high grade cervical lesions in older women is still important. Hormonal contraceptives (HC) and smoking are recognised cofactors for the development of pre-malignant lesions...
July 3, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29980027/benzene-exposure-at-workplace-and-risk-of-colorectal-cancer-in-four-nordic-countries
#7
Madar Talibov, Jorma Sormunen, Johnni Hansen, Kristina Kjaerheim, Jan-Ivar Martinsen, Per Sparen, Laufey Tryggvadottir, Elisabete Weiderpass, Eero Pukkala
OBJECTIVE: The aim of this case-control study was to assess the effect of occupational benzene exposure on the risk of colorectal cancer, including its subtypes. METHODS: The study included 181,709 colon cancer and 109,227 rectal cancer cases diagnosed between 1961 and 2005 in Finland, Iceland, Norway and Sweden. Cases were identified from the Nordic Occupational Cancer Study (NOCCA) cohort. Five controls per case were selected from the same cohort, matched for country, birth year, and sex...
July 2, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29980026/hbv-infection-and-extra-hepatic-cancers-in-adolescents-and-20s-a-retrospective-study-in-china
#8
Tingna Lu, Qing Yang, Mei Li, Jiqing Zhang, Jing Zou, Lu Huang, Jianhua Lin, Haosheng Jin, Jiman He
BACKGROUND: The mean age at cancer diagnosis is younger in hepatitis B virus (HBV) infected than non-infected patients. It remains unknown whether this association reflects an increase in the incidence rates of extra-hepatic cancers in adolescents and younger. METHODS: We examined 10 common extra-hepatic cancers (lung, breast, gastric, prostate, esophageal, rectal, cervical, nasopharyngeal, lymphatic, and urinary bladder) among patients diagnosed at three Chinese hospitals during 2007-2016...
June 30, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29960925/consultation-frequency-in-general-practice-before-cancer-diagnosis-in-relation-to-the-patient-s-usual-consultation-pattern-a-population-based-study
#9
Henry Jensen, Peter Vedsted, Henrik Møller
BACKGROUND: Cancer patients who usually consult the general practitioner (GP) rarely are generally diagnosed with more advanced stages of cancer. This subgroup of cancer patients may thus postpone relevant healthcare seeking. AIM: We aimed to investigate the rates of daytime face-to-face consultations in general practice before a cancer diagnosis in patients with different categories of 'usual' consultation frequency. MATERIAL AND METHODS: We conducted a population-based comparative study using register data on all 123,934 first-time cancer patients aged 50-90 years who were diagnosed in 2009-2013 in Denmark...
June 28, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29957398/epidemiology-of-multiple-myeloma-in-taiwan-a-population-based-study
#10
Chao-Hsiun Tang, Hung-Yi Liu, Hsin-An Hou, Hong Qiu, Kuan-Chih Huang, Sarah Siggins, Lee Anne Rothwell, Yanfang Liu
BACKGROUND: Although the incidence of multiple myeloma (MM) in Asia is lower than in Western countries, it is steadily increasing. However, limited data are available that describe the epidemiology of MM in Asia. METHODS: We conducted a retrospective cohort study using the Taiwan National Healthcare Insurance Research database to estimate the disease burden and clinical characteristics of patients with MM in Taiwan. All newly diagnosed confirmed MM patients during 2007-2012 were enrolled...
June 24, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29945094/mortality-of-patients-examined-at-a-diagnostic-centre-a-matched-cohort-study
#11
Esben Næser, Henrik Møller, Ulrich Fredberg, Peter Vedsted
BACKGROUND: 'Diagnostic Centres' has been established to provide a diagnostic pathway for patients with non-specific, serious symptoms that could be cancer. As little is known about the prognosis, we aimed to 1) analyse mortality of patients examined at the diagnostic centre, stratified on diagnostic outcome (cancer, serious-non-malignant disease, or other/no diagnosis), and 2) compare mortality for cancer patients examined at the diagnostic centre with cancer patients diagnosed through other routes...
June 23, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29940418/anxiety-and-depression-in-women-with-breast-cancer-social-and-clinical-determinants-and-influence-of-the-social-network-and-social-support-dama-cohort
#12
R Puigpinós-Riera, A Graells-Sans, G Serral, X Continente, X Bargalló, M Domènech, M Espinosa-Bravo, J Grau, F Macià, R Manzanera, M Pla, M J Quintana, M Sala, E Vidal
BACKGROUND: Anxiety and depression are the most prevalent mental health pathologies among women with breast cancer. Social, clinical and contextual variables may influence emotional stress among women with breast cancer. The aim of this work is to study anxiety and depression in a cohort of women diagnosed with breast cancer between 2003 and 2013 in Barcelona. We evaluate social and clinical determinants. METHODS: We performed a mixed cohort study (prospective and retrospective) using a convenience sample of women diagnosed with breast cancer...
June 22, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29936140/the-scientific-impact-and-value-of-large-nci-sponsored-randomized-phase-iii-cancer-chemoprevention-trials
#13
Joseph M Unger, William E Barlow, Catherine M Tangen, Scott D Ramsey, Ian M Thompson, Eric A Klein, Michael LeBlanc, Charles D Blanke, Phyllis J Goodman, Lori M Minasian, Van T Nghiem, Dawn L Hershman
BACKGROUND: The cancer research groups of the National Cancer Institute's National Clinical Trials Network have a history of successful conduct of large randomized phase III trials of chemoprevention for cancer. An important question for funding agencies is whether the conduct of large chemoprevention trials provides strong scientific return on investment. METHODS: We evaluated the scientific impact of four large chemoprevention trials - two for breast cancer and two for prostate cancer - using citation analysis, a bibliometric technique...
June 21, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29935395/risk-of-high-grade-serous-ovarian-cancer-associated-with-pelvic-inflammatory-disease-parity-and-breast-cancer
#14
Louise M Stewart, Katrina Spilsbury, Susan Jordan, Colin Stewart, C D'Arcy J Holman, Aime Powell, Joanne Reekie, Paul Cohen
BACKGROUND: Ovarian carcinoma is not a single disease, but rather a collection of subtypes with differing molecular properties and risk profiles. The most common of these, and the subject of this work, is high-grade serous ovarian carcinoma (HGSC). METHODS: In this population-based study we identified a cohort of 441,382 women resident in Western Australia who had ever been admitted to hospital in the State. Of these, 454 were diagnosed with HGSC. We used Cox regression to derive hazard ratios (HRs) comparing the risk of disease in women who had each of a range of medical diagnoses and surgical procedures with women who did not...
June 20, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29902672/childhood-cancer-registration-in-new-zealand-a-registry-collaboration-to-asssess-and-improve-data-quality
#15
Kirsten R Ballantine, Susan Hanna, Scott Macfarlane, Peter Bradbeer, Lochie Teague, Sarah Hunter, Siobhan Cross, Jane Skeen
AIM: To evaluate the completeness and accuracy of child cancer registration in New Zealand. METHODS: Registrations for children aged 0-14 diagnosed between 1/1/2010 and 31/12/2014 were obtained from the New Zealand Cancer Registry (NZCR) and the New Zealand Children's Cancer Registry (NZCCR). Six key data fields were matched using National Health Index numbers in order to identify and resolve registration discrepancies. Capture-recapture methods were used to assess the completeness of cancer registration...
June 11, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29883839/genetic-polymorphisms-of-th2-interleukins-history-of-asthma-or-eczema-and-childhood-acute-lymphoid-leukaemia-findings-from-the-escale-study-sfce
#16
A Bonaventure, L Orsi, J Rudant, S Goujon-Bellec, G Leverger, A Baruchel, Y Bertrand, B Nelken, M Pasquet, G Michel, N Sirvent, P Chastagner, S Ducassou, C Thomas, C Besse, D Hémon, J Clavel
BACKGROUND: Previous studies on the putative role of allergy in the aetiology of childhood leukaemia have reported contradictory results. The present study aimed to analyse the relation between a medical history of asthma or eczema and childhood acute lymphoid leukaemia (ALL) in light of potential candidate gene-environment interactions. METHODS: Analyses were based on a subset of 434 cases of ALL and 442 controls successfully genotyped and of European ancestry children enrolled in a French population-based case-control study conducted in 2003-2004...
June 5, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29861403/erratum-to-plasma-magnesium-is-inversely-associated-with-epstein-barr-virus-load-in-peripheral-blood-and-burkitt-lymphoma-in-uganda-cancer-epidemiol-52-2018-70-74
#17
Juan Ravell, Isaac Otim, Hadijah Nabalende, Ismail D Legason, Steven J Reynolds, Martin D Ogwang, Christopher M Ndugwa, Vickie Marshall, Denise Whitby, James J Goedert, Eric A Engels, Kishor Bhatia, Michael J Lenardo, Sam M Mbulaiteye
No abstract text is available yet for this article.
June 1, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29859499/prevalence-of-hereditary-cancer-susceptibility-syndromes-in-children-with-cancer-in-a-highly-consanguineous-population
#18
Wasil Jastaniah, Abdullah Aljefri, Mouhab Ayas, Musa Alharbi, Nawaf Alkhayat, Faisal Al-Anzi, Fawwaz Yassin, Fawaz Alkasim, Qasim Alharbi, Shaker Abdullah, Mohammed Burhan Abrar, Abdulrahman Alsultan
BACKGROUND & AIM: Hereditary cancer susceptibility syndromes (HCSS) are reported in up to one-third of children with cancer. Diagnosis of HCSS is crucial for implementation of surveillance protocols. We identified children who fulfilled criteria for HCSS in Saudi Arabia using the American College of Medical Genetics and Genomics (ACMG) guidelines, addressing the utility of these guidelines in a highly consanguineous population. METHODS: This multi-center cross-sectional study recruited 1858 children with cancer between January 2011 and December 2014...
May 30, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29852396/trends-in-thyroid-cancer-retrospective-analysis-of-incidence-and-survival-in-denmark-1980-2014
#19
Christian Mirian, Christian Grønhøj, David Hebbelstrup Jensen, Kathrine Kronberg Jakobsen, Kirstine Karnov, Jakob Schmidt Jensen, Christoffer Holst Hahn, Tina Agander Klitmøller, Jens Bentzen, Christian von Buchwald
BACKGROUND: Thyroid cancer incidence has been reported to be increasing since the 1970 s. The aim of this study was to investigate the change in incidence and survival from 1980 to 2014 in Denmark. METHODS: We identified patients registered with thyroid cancer in the period 1980-2014. We evaluated the age-adjusted incidence rate (AAIR) and the average annual percentage change (AAPC), constructed age-period-cohort models (APCs), and evaluated relative survival (RS)...
May 28, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29843073/breast-and-cervical-cancer-incidence-and-mortality-trends-in-russia-1980-2013
#20
Anton Barchuk, Alexander Bespalov, Heini Huhtala, Tuvshinjargal Chimed, Irina Laricheva, Alexey Belyaev, Freddie Bray, Ahti Anttila, Anssi Auvinen
BACKGROUND: Breast and cervical cancer are among the leading causes of preventable cancer deaths in women in Russia. The aim of this study is to analyze changes in breast and cervical cancer incidence and mortality trends using data from the Russian State Cancer Registry. METHODS: The age-standardized rates of cervical cancer incidence (1993-2013) and mortality (1980-2013) were analyzed using piecewise linear regression. Age-period-cohort models were used to estimate the temporal effects and provide future predictions...
May 26, 2018: Cancer Epidemiology
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