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Cancer Epidemiology

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https://www.readbyqxmd.com/read/28319725/antiestrogen-use-in-breast-cancer-patients-reduces-the-risk-of-subsequent-lung-cancer-a-population-based-study
#1
Sung-Chao Chu, Chia-Jung Hsieh, Tso-Fu Wang, Mun-Kun Hong, Tang-Yuan Chu
BACKGROUND: There is accumulating epidemiological and preclinical evidence that estrogen might be a driver of lung cancer. Breast cancer survivors can offer a unique patient cohort to examine the effect of antiestrogen therapy on lung cancer carcinogenesis because many of these women would have received long-term selective estrogen receptor modulators (SERMs) and/or aromatase inhibitors (AIs) as adjuvant treatment. Our hypothesis is that estrogens play a role in lung cancer development, and that antiestrogen therapy would affect the incidence of subsequent lung cancer among breast cancer survivors...
March 17, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28315607/correcting-bias-due-to-missing-stage-data-in-the-non-parametric-estimation-of-stage-specific-net-survival-for-colorectal-cancer-using-multiple-imputation
#2
Milena Falcaro, James R Carpenter
BACKGROUND: Population-based net survival by tumour stage at diagnosis is a key measure in cancer surveillance. Unfortunately, data on tumour stage are often missing for a non-negligible proportion of patients and the mechanism giving rise to the missingness is usually anything but completely at random. In this setting, restricting analysis to the subset of complete records gives typically biased results. Multiple imputation is a promising practical approach to the issues raised by the missing data, but its use in conjunction with the Pohar-Perme method for estimating net survival has not been formally evaluated...
March 15, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28314172/the-risk-of-cancer-in-the-offspring-and-parental-length-of-life
#3
Ruby Del Risco Kollerud, Karl Gerhard Blaasaas, Bjørgulf Claussen, Bente Oftedal, Øyvind Næss
BACKGROUND: We investigated if cancer onset in offspring is related to having short-lived parents for different cancer types and to see if there was a difference in smoking- and non-smoking related cancers. METHODS: Our study included 524,391 individuals born in Norway 1940-1950. All children were followed up for cancer from the age of 20 until they were between 59 and 69 years. Parental longevity was examined by grouping parental age of death into parents dying before 75 years of age and parents dying at 75 years of age or older...
March 14, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28291679/low-dose-aspirin-use-and-survival-in-breast-cancer-patients-a-nationwide-cohort-study
#4
LETTER
Úna Mc Menamin, Chris Cardwell, Carmel Hughes, Liam Murray
No abstract text is available yet for this article.
March 10, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28282541/measures-of-economic-advantage-associated-with-hpv-positive-head-and-neck-cancers-among-non-hispanic-black-and-white-males-identified-through-the-national-cancer-database
#5
Caryn E Peterson, Shaveta Khosla, Gina D Jefferson, Faith G Davis, Marian L Fitzgibbon, Sally Freels, Timothy P Johnson, Kent Hoskins, Charlotte E Joslin
BACKGROUND: National trends show dramatic increases in the incidence of HPV-related head and neck squamous cell carcinomas (HNSCCs) among black and white males. Using cases identified through the National Cancer Data Base, we assessed factors associated with HPV 16- or 16/18 positive HNSCCs among non-Hispanic black and white males diagnosed in the U.S. between 2009 and 2013. METHODS: This sample included 21,524 HNSCCs with known HPV status. Adjusted relative risks (RRs) and 95% confidence intervals (CIs) were estimated using log-binomial regression...
March 7, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28274695/a-pathologist-s-perspective-on-thyroid-cancer-trends-in-thailand
#6
LETTER
Andrey Bychkov
No abstract text is available yet for this article.
March 5, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28268206/profile-of-cancer-in-the-eastern-mediterranean-region-the-need-for-action
#7
Ivana Kulhánová, Freddie Bray, Ibtihal Fadhil, Ali Saeed Al-Zahrani, Amani El-Basmy, Wagida A Anwar, Amal Al-Omari, Ali Shamseddine, Ariana Znaor, Isabelle Soerjomataram
BACKGROUND: Many countries in the Eastern Mediterranean region (EMR) are undergoing marked demographic and socioeconomic transitions that are increasing the cancer burden in region. We sought to examine the national cancer incidence and mortality profiles as a support to regional cancer control planning in the EMR. METHODS: GLOBOCAN 2012 data were used to estimate cancer incidence and mortality by country, cancer type, sex and age in 22 EMR countries. We calculated age-standardized incidence and mortality rates (per 100,000) using direct method of standardization...
March 4, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28268162/association-between-aspirin-use-triple-negative-breast-cancer-more-benefit-is-expected
#8
LETTER
Kadri Altundag
No abstract text is available yet for this article.
March 4, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28259083/environmental-heavy-metal-as-a-potential-risk-factor-for-the-progression-of-oral-potentially-malignant-disorders-in-central-taiwan
#9
Kuo-Yang Tsai, Che-Chun Su, Chi-Ting Chiang, Yao-Ting Tseng, Ie-Bin Lian
OBJECTIVE: Oral cancer (OC) is a leading cause of death from cancer in men between the ages of 25 and 44 years in Taiwan. The overall 5-year survival rates for the four OC stages (I-IV) in Taiwan are approximately 70%, 30%, 20%, and 10%, respectively, indicating the importance of the early diagnosis of oral potentially malignant disorders (OPMDs). Previous studies indicated an association between the OC incidence and certain environmental heavy metal concentrations. If these associations do exist for OC, they may also be observed for OPMD...
March 1, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28258029/incidence-trends-in-oesophageal-cancer-by-histological-type-an-updated-analysis-in-sweden
#10
Shao-Hua Xie, Fredrik Mattsson, Jesper Lagergren
BACKGROUND: We aimed to update incidence trends of oesophageal cancer by histological type in Sweden. METHODS: Using data from the Swedish Cancer Registry, we examined incidence trends of oesophageal cancer by histological types in individuals aged ≥50 years in 1970-2014 using log-linear joinpoint regressions. RESULTS: The age-standardised incidence rate of oesophageal adenocarcinoma in men increased on average by 3.0% per year in 1970-1994, followed by a more rapid increase of 13...
February 28, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28242577/risk-of-second-primary-cancer-associated-with-pre-diagnostic-smoking-alcohol-and-obesity-in-women-with-keratinocyte-carcinoma
#11
Sang Min Park, Tricia Li, Shaowei Wu, Wen-Qing Li, Abrar A Qureshi, Meir Stampfer, Eunyoung Cho
Keratinocyte carcinoma (KC), which includes basal-cell carcinoma (BCC) and squamous-cell cancer (SCC), has been associated with an increased risk of second primary cancers (SPCs), although the reason for this increase is unknown. We assessed the effects of smoking, alcohol, and obesity prior to the diagnosis of KC on the development of SPCs, as these are well-established risk factors for multiple cancers and may also contribute to the increased risk of SPCs among those with KC. A total of 15,628 women with self-reported KC were identified in the Nurses' Health Study...
February 24, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28236754/lymphohaematopoietic-malignancies-in-scottish-military-veterans-retrospective-cohort-study-of-57-000-veterans-and-173-000-non-veterans
#12
Beverly P Bergman, Daniel F Mackay, Jill P Pell
BACKGROUND: Lymphohaematopoietic malignancies are common in the general population. There have been concerns that military service may be associated with increased risk as a result of occupational exposures. To date, few studies have demonstrated an increased risk, although a disability pension is payable to veterans who were present at nuclear tests and who develop leukaemia (other than chronic lymphocytic leukaemia). The aim of the study was to utilise data from the Scottish Veterans Health Study to examine the risk of lymphohaematopoietic malignancy following military service in a large national cohort of veterans...
February 22, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28192742/breast-cancer-detection-using-single-reading-of-breast-tomosynthesis-3d-mammography-compared-to-double-reading-of-2d-mammography-evidence-from-a-population-based-trial
#13
Nehmat Houssami, Daniela Bernardi, Marco Pellegrini, Marvi Valentini, Carmine Fantò, Livio Ostillio, Paolina Tuttobene, Andrea Luparia, Petra Macaskill
BACKGROUND: Most population breast cancer (BC) screening programs use double-reading of 2D-mammography. We recently reported the screening with tomosynthesis or standard mammography-2 (STORM-2) trial, showing that double-read tomosynthesis (pseudo-3D-mammography) detected more BC than double-read 2D-mammography. In this study, we compare screen-detection measures for single-reading of 3D-mammography with those for double-reading of 2D-mammography, to inform screening practice. METHODS: This is a secondary analysis based on STORM-2 which prospectively compared 3D-mammography and 2D-mammography in sequential screen-readings...
February 10, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28167416/the-relationship-between-ethnicity-social-deprivation-and-late-presentation-of-colorectal-cancer
#14
Alan Askari, Subramanian Nachiappan, Andrew Currie, Andrew Latchford, Justin Stebbing, Alex Bottle, Thanos Athanasiou, Omar Faiz
INTRODUCTION: Tumour staging at time of presentation is an important factor in determining survival in colorectal cancer. The aim of this paper is to investigate the relationship between ethnicity and deprivation in late (Stage IV) presentation of colorectal cancer. METHODS: Data from the Thames Cancer Registry comprising 77,057 colorectal cancer patients between the years 2000 and 2012 were analysed. RESULTS: A total of 17,348 patients were identified with complete data, of which 53...
February 3, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28153669/coffee-and-tea-consumption-and-risk-of-leukaemia-in-an-adult-population-a-reanalysis-of-the-italian-multicentre-case-control-study
#15
Stefano Parodi, Domenico Franco Merlo, Emanuele Stagnaro
BACKGROUND: Coffee and tea are the most frequently consumed beverages in the world. Their potential effect on the risk of developing different types of malignancies has been largely investigated, but studies on leukaemia in adults are scarce. METHODS: The present investigation is aimed at evaluating the potential role of regular coffee and tea intake on the risk of adult leukaemia by reanalysing a large population based case-control study carried out in Italy, a country with a high coffee consumption and a low use of green tea...
January 30, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28131793/rosacea-and-risk-of-cancer-in-denmark
#16
Alexander Egeberg, Joseph F Fowler, Gunnar H Gislason, Jacob P Thyssen
BACKGROUND: Rosacea is a common facial skin disorder with an estimated prevalence of 5-10% among Caucasians. OBJECTIVE: We compared cancer incidence in patients previously diagnosed with rosacea with that in the general population. METHODS: Nationwide cohort study of the Danish population using individual-level linkage of administrative registers. All Danish citizens aged ≥18years were followed from January 1st 2008 to December 31st 2012...
January 26, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28130996/association-of-maternal-and-index-child-s-diet-with-subsequent-leukemia-risk-a-systematic-review-and-meta-analysis
#17
REVIEW
Nick Dessypris, Maria A Karalexi, Evangelos Ntouvelis, Andreas-Antonios Diamantaras, Vassilios Papadakis, Margarita Baka, Emmanuel Hatzipantelis, Maria Kourti, Maria Moschovi, Sophia Polychronopoulou, Vasiliki Sidi, Eftichia Stiakaki, Eleni Th Petridou
BACKGROUND: Exploring the effect of maternal and/or childhood diet on offspring leukemogenesis is challenging, given differences in food group categories, their potentially variable impact depending on time window of exposure and the multiple leukemia subtypes. We opted to quantitatively synthesize published data on the association of maternal/child diet with leukemia risk. METHODS: Medline was searched until June 30th, 2016 for eligible articles on the association of childhood leukemia with consumption of (i) food groups, excluding alcoholic and non-alcoholic beverages, and (ii) specific dietary supplements before/during index pregnancy and childhood...
January 25, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28126584/obesity-physical-activity-and-cancer-risks-results-from-the-cancer-lifestyle-and-evaluation-of-risk-study-clear
#18
Carlos Nunez, Adrian Bauman, Sam Egger, Freddy Sitas, Visalini Nair-Shalliker
INTRODUCTION: Physical activity (PA) has been associated with lower risk of cardiovascular diseases, but the evidence linking PA with lower cancer risk is inconclusive. We examined the independent and interactive effects of PA and obesity using body mass index (BMI) as a proxy for obesity, on the risk of developing prostate (PC), postmenopausal breast (BC), colorectal (CRC), ovarian (OC) and uterine (UC) cancers. METHODS: We estimated odds ratios (OR) and 95% confidence intervals (CI), adjusting for cancer specific confounders, in 6831 self-reported cancer cases and 1992 self-reported cancer-free controls from the Cancer Lifestyle and Evaluation of Risk Study, using unconditional logistic regression...
January 23, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28126583/time-to-diagnosis-and-stage-of-symptomatic-colorectal-cancer-determined-by-three-different-sources-of-information-a-population-based-retrospective-study
#19
Alfonso Leiva, Magdalena Esteva, Joan Llobera, Francesc Macià, Salvador Pita-Fernández, Luis González-Luján, María A Sánchez-Calavera, María Ramos
BACKGROUND: Survival rates from colorectal cancer (CRC) are highly variable in Europe. This variability could potentially be explained by differences in healthcare system delays in diagnosis. However, even when such delays are reduced, the relationship of the diagnostic interval (time from presentation with symptoms to diagnosis) with outcome is uncertain. METHODS: A total of 795 patients with CRC from 5 regions of Spain were retrospectively examined in this population-based multicenter study...
January 23, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28119121/incidence-mortality-and-receptor-status-of-breast-cancer-in-african-caribbean-women-data-from-the-cancer-registry-of-guadeloupe
#20
J Deloumeaux, S Gaumond, B Bhakkan, Nsome Manip M'Ebobisse, W Lafrance, Pierre Lancelot, D Vacque, Y Negesse, A Diedhiou, P Kadhel
BACKGROUND: Geographical disparities in breast cancer incidence and outcomes are reported worldwide. Women of African descent show lower incidence, higher mortality rates and earlier age of onset. We analyzed data from the cancer registry of Guadeloupe for the period 2008-2013. METHODS: We describe breast cancer characteristics by molecular subtype, as well as estimated observed and net survival. We used Cox proportional hazard models to determine associations between cancer subtypes and death rate, adjusted for variables of interest...
January 21, 2017: Cancer Epidemiology
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