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Methodist DeBakey Cardiovascular Journal

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https://www.readbyqxmd.com/read/27826380/an-answered-prayer
#1
JaMís Monet Jackson
No abstract text is available yet for this article.
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27826379/checkmate-and-devil-s-tower
#2
(no author information available yet)
No abstract text is available yet for this article.
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27826378/be-an-expatriate-for-a-week-ad-in-a-writers-journal
#3
(no author information available yet)
No abstract text is available yet for this article.
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27826377/electrolyte-games-for-rainy-afternoons
#4
Juan Jose Olivero
No abstract text is available yet for this article.
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27826376/pannus-of-mitral-valve-prosthesis-causing-left-ventricular-outflow-tract-obstruction
#5
Muaz M Abudiab, Joshua McKay, Michael Deavers, William A Zoghbi, Su Min Chang
No abstract text is available yet for this article.
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27826375/metastatic-breast-carcinoma-to-the-coronaries-a-rare-cause-of-acute-myocardial-infarction
#6
Nicholas Bhojwani, Alok Harwani, Jason B Hartman, Sasan Partovi, Robert C Gilkeson
A 63-year-old female with a history of invasive ductal breast carcinoma presented to the emergency department with symptoms characteristic of myocardial infarction. Electrocardiography showed sinus tachycardia and ST elevations in leads II, III, and aVF, consistent with inferior wall myocardial infarction. A computed tomography (CT) scan of the chest, abdomen, and pelvis with intravenous contrast demonstrated widespread intrathoracic metastatic disease. Cardiac magnetic resonance imaging (MRI) with contrast revealed obstruction of the left ventricular (LV) outflow tract by an LV mass...
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27826374/position-dependent-ventricular-tachycardia-related-to-peripherally-inserted-central-venous-catheter
#7
Paulino Alvarez, Paul Schurmann, Melanie Smith, Miguel Valderrábano, C Huie Lin
We report a case of a 51-year-old male who developed frequent nonsustained episodes of monomorphic ventricular tachycardia after being diagnosed with bioprosthetic aortic valve endocarditis and treated with intravenous antibiotics. A peripherally inserted central venous catheter (PICC) had been placed without complication less than 24 hours prior to the episodes. Ventricular tachycardia (VT) occurred during the night, while sleeping, when he assumed a right lateral decubitus position with abduction of the right arm and placement of the forearm under his head...
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27826373/acute-cardiac-tamponade-in-a-58-year-old-male-with-poststreptococcal-glomerulonephritis
#8
Wendy Bottinor, Daniel Fronk, Salima Sadruddin, Harriet Foster, Nilang Patel, Andreas Prinz, Ion S Jovin
Pericarditis in conjunction with nephritis is an uncommon clinical scenario with a broad differential diagnosis. We present the case of a 58-year-old male who developed nephritis and pericardial effusion with tamponade physiology. In the following, we discuss the differential diagnosis for concomitant nephritis and pericarditis and discuss the work-up performed on our patient. We also review the epidemiology of postinfectious glomerulonephritis in adults and describe previous cases of Streptococcus pyogenes pericarditis in the literature...
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27826372/vascular-inflammation-a-novel-access-route-for-nanomedicine
#9
Roberto Molinaro, Christian Boada, Guillermo Medrano Del Rosal, Kelly A Hartman, Claudia Corbo, Elizabeth D Andrews, Naama E Toledano-Furman, John P Cooke, Ennio Tasciotti
Despite an improved understanding of its pathophysiology and a wide range of new treatments, cardiovascular disease (CVD) remains a serious public health issue and the number one cause of mortality in the United States. Conditions that promote chronic systemic inflammation, such as obesity, cancer, and autoimmune and infectious diseases, are now known to play an important role in promoting CVD by inducing the expression of endothelial adhesion molecules and chemokines; these in turn promote leukocyte adherence and infiltration, which initiates and spurs the progression of CVD...
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27826371/enhancing-stent-effectiveness-with-nanofeatures
#10
Nicole Bassous, John P Cooke, Thomas J Webster
Drug-eluting stents are an effective therapy for symptomatic arterial obstructions, substantially reducing the incidence of restenosis by suppressing the migration and proliferation of vascular smooth muscle cells into the intima. However, current drug-eluting stents also inhibit the growth of endothelial cells, which are required to cover the vascular stent to reduce an excessive inflammatory response. As a result, the endothelial lining of the lumen is not regenerated. Since the loss of this homeostatic monolayer increases the risk of thrombosis, patients with drug-eluting stents require long-term antithrombotic therapy...
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27826370/novel-nanoprinting-for-oral-delivery-of-poorly-soluble-drugs
#11
Cihan Yilmaz, Can Sarisozen, Vladimir Torchilin, Ahmed Busnaina
Many of the newly developed drugs for cancer, and some of those for cardiovascular disease, are poorly soluble in water and cannot be taken orally. This can be overcome by employing a new and effective delivery system utilizing nanotechnology. We present a new method for oral preparation of poorly soluble drugs that entails assembling (printing) drug-loaded polymeric micelles into sub-100 nm orally acceptable nanorods (NRs). Due to their small size, these NRs will have a high permeability through cells and thus should transport through the intestine to allow for drug delivery in the blood...
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27826369/targeted-delivery-of-shear-stress-inducible-micrornas-by-nanoparticles-to-prevent-vulnerable-atherosclerotic-lesions
#12
Wing Tak Wong, Shuangtao Ma, Xiao Yu Tian, Andrea Banuet Gonzalez, Eno E Ebong, Haifa Shen
Atherosclerosis is a chronic inflammatory vascular wall disease, and endothelial cell dysfunction plays an important role in its development and progression. Under the influence of laminar shear stress, however, the endothelium releases homeostatic factors such as nitric oxide and expresses of vasoprotective microRNAs that are resistant to atherosclerosis. Adhesion molecules such as E-selectin, exhibited on the endothelial surface, recruit monocytes that enter the vessel wall to form foam cells. Accumulation of these foam cells form fatty streaks that may progress to atherosclerotic plaques in the blood vessel wall...
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27826368/native-and-reconstituted-plasma-lipoproteins-in-nanomedicine-physicochemical-determinants-of-nanoparticle-structure-stability-and-metabolism
#13
Henry J Pownall, Corina Rosales, Baiba K Gillard, Mauro Ferrari
Although many acute and chronic diseases are managed via pharmacological means, challenges remain regarding appropriate drug targeting and maintenance of therapeutic levels within target tissues. Advances in nanotechnology will overcome these challenges through the development of lipidic particles, including liposomes, lipoproteins, and reconstituted high-density lipoproteins (rHDL) that are potential carriers of water-soluble, hydrophobic, and amphiphilic molecules. Herein we summarize the properties of human plasma lipoproteins and rHDL, identify the physicochemical determinants of lipid transfer between phospholipid surfaces, and discuss strategies for increasing the plasma half-life of lipoprotein- and liposome-associated molecules...
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27826367/local-inhibition-of-macrophage-and-smooth-muscle-cell-proliferation-to-suppress-plaque-progression
#14
Roman A Sukhovershin, Naama E Toledano Furman, Ennio Tasciotti, Barry H Trachtenberg
Atherosclerosis is a complex process responsible for a major burden of cardiovascular morbidity and mortality. Macrophages and smooth muscle cells (SMCs) are abundant within atherosclerotic plaques. This review discusses the role of macrophages and SMCs in plaque progression and provides an overview of nanoparticle-based approaches and other current methods for local targeting of atherosclerotic plaques.
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27826366/nucleic-acid-delivery-for-endothelial-dysfunction-in-cardiovascular-diseases
#15
Dipti Deshpande, David R Janero, Victor Segura-Ibarra, Elvin Blanco, Mansoor M Amiji
Endothelial dysfunction has been implicated in the pathophysiology of multiple cardiovascular diseases and involves components of both innate and acquired immune mechanisms. Identifying signature patterns and targets associated with endothelial dysfunction can help in the development of novel nanotherapeutic platforms for treatment of vascular diseases. This review discusses nucleic acid-based regulation of endothelial function and the different nucleic acid-based nanotherapeutic approaches designed to target endothelial dysfunction in cardiovascular disorders...
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27826365/nanotherapeutic-solutions-for-cardiovascular-disease
#16
EDITORIAL
John P Cooke, Johnique Atkins
No abstract text is available yet for this article.
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27826364/guest-editor-john-cooke-offers-expertise-and-insight-on-nanotherapeutic-solutions-for-cardiovascular-diseases
#17
(no author information available yet)
No abstract text is available yet for this article.
September 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27486503/letter-to-the-editor
#18
Poovendran Saththasivam, Elizabeth Hererra
No abstract text is available yet for this article.
April 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27486502/lighting-the-way
#19
Jordan Roberts
No abstract text is available yet for this article.
April 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27486501/bullseye
#20
(no author information available yet)
No abstract text is available yet for this article.
April 2016: Methodist DeBakey Cardiovascular Journal
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