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Open Biomedical Engineering Journal

Carmen D'Anna, Maurizio Schmid, Andrea Scorza, Salvatore A Sciuto, Luisa Lopez, Silvia Conforto
BACKGROUND: The development of postural control across the primary school time horizon is a complex process, which entails biomechanics modifications, the maturation of cognitive ability and sensorimotor organization, and the emergence of anticipatory behaviour. Postural stability in upright stance has been thus object of a multiplicity of studies to better characterize postural control in this age span, with a variety of methodological approaches. The analysis of the Time-to-Boundary function (TtB), which specifies the spatiotemporal proximity of the Centre of Pressure (CoP) to the stability boundaries in the regulation of posture in upright stance, is among the techniques used to better characterize postural stability in adults, but, as of now, it has not yet been introduced in developmental studies...
2017: Open Biomedical Engineering Journal
Yoko Kato, Michelle L Oyen, Graham J Burton
BACKGROUND: In the human placenta, maternal and fetal bloods exchange substances through the surface of the villous trees: the fetal blood circulates in the villous trees, around which the maternal blood circulates. The blood flows directly influence fetal growth. Stem villi, the main supports of the villous tree, have contractile cells along the axes, whose contractions are expected to influence the blood circulations in the placenta. The displacement is neither measurable nor predictable while non-invasive measurements such as umbilical Doppler waveforms are helpful to predict the histological changes of the villous trees and vascularization in the placenta...
2017: Open Biomedical Engineering Journal
Angela Agostinelli, Agnese Sbrollini, Luca Burattini, Sandro Fioretti, Francesco Di Nardo, Laura Burattini
BACKGROUND: Fetal well-being evaluation may be accomplished by monitoring cardiac activity through fetal electrocardiography. Direct fetal electrocardiography (acquired through scalp electrodes) is the gold standard but its invasiveness limits its clinical applicability. Instead, clinical use of indirect fetal electrocardiography (acquired through abdominal electrodes) is limited by its poor signal quality. OBJECTIVE: Aim of this study was to evaluate the suitability of the Segmented-Beat Modulation Method to denoise indirect fetal electrocardiograms in order to achieve a signal-quality at least comparable to the direct ones...
2017: Open Biomedical Engineering Journal
Angela Agostinelli, Ilaria Marcantoni, Elisa Moretti, Agnese Sbrollini, Sandro Fioretti, Francesco Di Nardo, Laura Burattini
BACKGROUND: Indirect fetal electrocardiography is preferable to direct fetal electrocardiography because of being noninvasive and is applicable also during the end of pregnancy, besides labor. Still, the former is strongly affected by noise so that even R-peak detection (which is essential for fetal heart-rate evaluations and subsequent processing procedures) is challenging. Some fetal studies have applied the Pan-Tompkins' algorithm that, however, was originally designed for adult applications...
2017: Open Biomedical Engineering Journal
Yu-Ping Qin, Shuang Zhang, Hai-Yan Liu, Yi-He Liu, You-Zhi Li, Xue Peng, Xiu Ma, Qi-Li Li, Xuan Huang
BACKGROUND: The galvanic coupling intra-body communication has low radiation and strong anti-interference ability, so it has many advantages in the wireless communication. METHOD: In order to analyze the effect of muscle tissue's characteristics upon the communication channel, we selected the muscle of pig buttock as the experimental sample, and used it to study the attenuation property with the galvanic coupling intra-body communication channel along the parallel direction and the transverse direction relative to the muscular fibre line as well as on the surface of destroyed muscular fibre; the study frequency ranges from 1kHz to 10MHz...
2017: Open Biomedical Engineering Journal
Tomohiro Fukui, Hiroaki Asama, Manabu Kimura, Toshiyuki Itoi, Koji Morinishi
BACKGROUND: The transposition of the great arteries (TGA) is one of the most severe congenital heart diseases. The arterial switch operation (ASO) is the preferred procedure to treat TGA. Although numerous reports have shown good results after ASOs, some patients suffer from circulatory system problems following the procedure. One reason for problems post-ASO is the local changes in the curvature and torsion of the thoracic aorta. OBJECTIVE: The influence of these geometric changes on the blood flow field needs to be investigated in detail to consider possible cardiovascular problems after an ASO...
2017: Open Biomedical Engineering Journal
Yen-Chen Hsu, Chung-Hung Tsai, Yu-Ming Kuo, Bella Ya-Hui
BACKGROUND: Several countries have recently attempted to implement telecare information technology to provide health care to older adults. This study applied self-determination theory (autonomy, relatedness, and competence) and the theory of planned behavior (subjective norm, perceived behavioral control, and attitudes toward using tools) to investigate a theoretical model for explaining the predictive factors influencing the intention of elderly patients to continue using telecare services...
2016: Open Biomedical Engineering Journal
Mara Terzini, Cristina Bignardi, Carlotta Castagnoli, Irene Cambieri, Elisabetta M Zanetti, Alberto L Audenino
BACKGROUND: The dermis is a commonly used source tissue for biologic scaffolds; all cellular and nuclear materials need to be removed to limit the inflammatory immune response by the host organism. The decellularization is critical because it must preserve the structural integrity of the extracellular matrix. This work has analyzed a decellularization procedure commonly followed for the dermal tissue that is a chemical treatment with sodium hydroxide. The goal of this work is to identify the optimal treatment length on the basis of structural properties...
2016: Open Biomedical Engineering Journal
Junhong Liu, Wanzhong Chen, Mingyang Li, Xiaotao Kang
BACKGROUND: While the classification of multifunctional finger and wrist movement based on surface electromyography (sEMG) signals in intact subjects can reach remarkable recognition rates, the performance obtained from amputated subjects remained low. METHODS: In this paper, we proposed and evaluated the myoelectric control scheme of upper-limb prostheses by the continuous recognition of 17 multifunctional finger and wrist movements on 5 amputated subjects. Experimental validation was applied to select optimal features and classifiers for identifying sEMG and accelerometry (ACC) modalities under the windows-based analysis scheme...
2016: Open Biomedical Engineering Journal
Zhang Wei
No abstract text is available yet for this article.
2016: Open Biomedical Engineering Journal
Xiaoyang Zhang, Lei Xue, Zhi Zhang, Yiwen Zhang
BACKGROUND: Health problems about children have been attracting much attention of parents and even the whole society all the time, among which, child-language development is a hot research topic. The experts and scholars have studied and found that the guardians taking appropriate intervention in children at the early stage can promote children's language and cognitive ability development effectively, and carry out analysis of quantity. The intervention of Artificial Intelligence Technology has effect on the autistic spectrum disorders of children obviously...
2016: Open Biomedical Engineering Journal
E G Yakovleva, K G Korotkov, E D Fedorov, E V Ivanova, R V Plahov, S S Belonosov
BACKGROUND: Colonic neoplasms are quite a serious problem today. Screening methods play an important role in diagnosing the disease. Colorectal cancer screening is a complex undertaking, having various options, which require a lot of efforts both from the doctor and from the patient, including the use of sedatives and the necessity of the presence of an assistant for some procedures such as colonoscopy. This is why it is very important to find a method by which one can make a diagnosis quickly, easily, and painlessly...
2016: Open Biomedical Engineering Journal
Andrew C Rau, Ryan Siskey, Jorge A Ochoa, Tracy Good
BACKGROUND: Creating appropriately-sized, lethal isotherms during cryoablation of renal tumors is critical in order to achieve sufficiently-sized zones of cell death. To ensure adequate cell death in target treatment locations, surgeons must carefully select the type, size, location, and number of probes to be used, as well as various probe operating parameters. OBJECTIVE: The current study investigates the effects of probe type, operating pressure, and clinical method on the resulting sizes of isotherms in an in vitro gelatin model...
2016: Open Biomedical Engineering Journal
Xiaoyuan Li, Qiwei Li, Li Shi, Liucheng Jiao
The response properties of individual neurons in the primary visual cortex (V1) are among the most thoroughly described in the mammalian central nervous system, but they reveal less about higher-order processes like visual perception. Neural activity is highly nonlinear and non-stationary over time, greatly complicating the relationships among the spatiotemporal characteristics of visual stimuli, local field potential (LFP) signal components, and the underlying neuronal activity patterns. We applied discrete wavelet transformation to detect new features of the LFP that may better describe the association between visual input and neural ensemble activity...
2016: Open Biomedical Engineering Journal
C Giuliani, A Agostinelli, F Di Nardo, S Fioretti, L Burattini
Electrocardiographic (ECG) T-wave endpoint (Tend) identification suffers lack of reliability due to the presence of noise and variability among leads. Tend identification can be improved by using global repolarization waveforms obtained by combining several leads. The dominant T-wave (DTW) is a global repolarization waveform that proved to improve Tend identification when computed using the 15 (I to III, aVr, aVl, aVf, V1 to V6, X, Y, Z) leads usually available in clinics, of which only 8 (I, II, V1 to V6) are independent...
2016: Open Biomedical Engineering Journal
Kai Chen, Min Pan, Zhi-Gang Feng
BACKGROUND: Micro-needles were proposed as one of the alternatives to deliver drugs painlessly passing through stratum corneum in recent years. In this work, a mathematical model is presented to characterize the in fusion flow of a hollow micro-needle array driven by a micro-pump. METHODS: By assuming the injection of each micro-needle undergoes a spherical expansion and diffusion, the model is able to calculate the time-varying expansion radius, and the diffusion boundary, provided that the material properties and the micro-needle system parameters are known...
2016: Open Biomedical Engineering Journal
Alexander P Dahinten, Robert A Malkin
INTRODUCTION: Modern day antiretroviral therapy allows HIV+ pregnant women to lower the likelihood of viral transmission to their infants before, during, and after birth from 20-45% to less than 5%. In developing countries, where non-facility births may outnumber facility births, infant access to safe antiretroviral medication during the critical first three days after birth is often limited. A single-dose, polyethylene pouch ("Pratt Pouch") addresses this challenge by allowing the medication to be distributed to mothers during antenatal care...
2016: Open Biomedical Engineering Journal
Tomokazu Masaoka, Toshitaka Yoshii, Masato Yuasa, Tsuyoshi Yamada, Takashi Taniyama, Ichiro Torigoe, Kenichi Shinomiya, Atsushi Okawa, Sadao Morita, Shinichi Sotome
BACKGROUND: Reconstruction of large bone defects is a great challenge in orthopedic research. In the present study, we prepared composites of bone marrow-derived stromal cells (BMSCs) and β-tricalcium phosphate (β-TCP) with three novel aspects: proliferation of BMSCs with continuous dexamethasone treatment, cell loading under low pressure, and use of autologous plasma as the cell loading medium. The effectiveness of the resulting composite for large bone-defect reconstruction was tested in a non-human primate model, and the bone union capability of the regenerated bones was examined...
2016: Open Biomedical Engineering Journal
(no author information available yet)
No abstract text is available yet for this article.
2016: Open Biomedical Engineering Journal
Cheng Kai, Zhang Denglan, Deng Jingxuan, Zhao Yijun
An Aeromonas punctata bacteriophage, named as DH1, was isolated from East Lake, Wuhan city, China. Morphologically, phage DH1 showed a typical Myoviridae structure consisting of an isometric head (50 nm in diameter) and a visible tail. The bacteriophage had a latent period of about 90 minutes and an average burst size of about 125 PFU•Cell(-1). Restriction enzyme pattern of the bacteriophage's genome showed that the genome is a double-stranded DNA and about 34kb in size. The sequenced genomic fragments showed highly similarities to gp04 and gp16 sequence of other Myoviridae bacteriophages at protein level...
2015: Open Biomedical Engineering Journal
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