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Open Biomedical Engineering Journal

Elvis K Tiburu, Ibrahim Issah, Mabel Darko, Robert E Armah-Sekum, Stephen O A Gyampo, Nadia K Amoateng, Samuel K Kwofie, Gordon Awandare
Background: Physiochemical factors such as temperature, pH and cofactors are well known parameters that confer conformational changes in a protein structure. With S100β protein being a metal binding brain-specific receptor for both extracellular and intracellular functions, a change in conformation due to the above-mentioned factors, can compromise their cellular functions and therefore result in several pathological conditions such as Alzheimer's disease, Ischemic stroke, as well as Myocardial Infarction...
2018: Open Biomedical Engineering Journal
Cristina Bignardi, Elisabetta M Zanetti, Mara Terzini, Anna R Ciccola, Gianmario Schierano, Alberto L Audenino
Background: Tooth-supported fixed dentures are commonly used in restorative dentistry, and have definitely reached a high survival rate; nevertheless, their removal is sometimes required mainly due to caries or other failures (poor fit, poor cementation and so on). Removing a definitive partial denture is not trivial since the used cement is not always known and it may be very resistant; additionally, there are various clinical circumstances in which a conservative disassembly would be desirable...
2018: Open Biomedical Engineering Journal
Luay Fraiwan, Jolu Ninan, Mohanad Al-Khodari
Purpose: The number of patients who are suffering from diabetes nowadays is increasing significantly. In some countries, the percentage of population who suffer from this disease can reach up to 20%. Diabetic patients have to deal with their medical conditions and any further complications that this disease may cause. One of the most common conditions is the Diabetic Foot Ulcer (DFU). The early detection of these ulcers can help and may save the life of diabetic patients. Methods: This work proposes a mobile application for the detection of possible ulcers using a smart phone along with a mobile thermal camera (FLIR ONE)...
2018: Open Biomedical Engineering Journal
Julia P Slopsema, John M Boss, Lane A Heyboer, Carson M Tobias, Brooke P Draggoo, Kathleen E Finn, Payton J Hoff, Katharine H Polasek
Background: Electrical stimulation is increasingly relevant in a variety of medical treatments. In this study, surface electrical stimulation was evaluated as a method to non-invasively target a neural function, specifically natural sensation in the distal limbs. Method: Electrodes were placed over the median and ulnar nerves at the elbow and the common peroneal and lateral sural cutaneous nerves at the knee. Strength-duration curves for sensation were compared between nerves...
2018: Open Biomedical Engineering Journal
Haralambia P Charalambous, Panayiotis C Roussis, Antonios E Giannakopoulos
Background: When subjected to time-dependent blood pressure, human arteries undergo large deformations, exhibiting mainly nonlinear hyperelastic type of response. The mechanical response of arteries depends on the health of tissues that comprise the artery walls. Typically, healthy arteries exhibit convex strain hardening under tensile loads, atherosclerotic parts exhibit stiffer response, and aneurysmatic parts exhibit softening response. In reality, arterial dynamics is the dynamics of a propagating pulse, originating in heart ventricle, propagating along aorta, bifurcating, etc ...
2017: Open Biomedical Engineering Journal
Franziska Ehlicke, Natascha Köster, Denise Salzig, Peter Czermak
BACKGROUND: The most common cause of lower back pain is the pathological degeneration of the nucleus pulposus (NP). Promising NP regeneration strategies involving human mesenchymal stem cells (hMSCs) would require specific markers to confirm successful differentiation into the NP lineage and to distinguish the articular cartilage (AC). OBJECTIVE: We sought specific NP mRNA markers that are upregulated in native NP cells but not in dedifferentiated NP cells, undifferentiated hMSCs or chondrocytes...
2017: Open Biomedical Engineering Journal
Kai Chen, Min Pan, Tingting Liu
BACKGROUND: Liquid needle-free injection devices (NFIDs) employ a high-velocity liquid jet to deliver drugs and vaccine through transdermal injection. NFIDs for animal vaccination are more complicated than those used for human beings for their much larger and more flexible power sources, as well as rapid, repetitive and continuous injection features. METHOD: In the paper, spring-powered NFID is designed for animal vaccine injection. For convenience, the device is a split into a power source and handheld injector...
2017: Open Biomedical Engineering Journal
Carmen D'Anna, Maurizio Schmid, Andrea Scorza, Salvatore A Sciuto, Luisa Lopez, Silvia Conforto
BACKGROUND: The development of postural control across the primary school time horizon is a complex process, which entails biomechanics modifications, the maturation of cognitive ability and sensorimotor organization, and the emergence of anticipatory behaviour. Postural stability in upright stance has been thus object of a multiplicity of studies to better characterize postural control in this age span, with a variety of methodological approaches. The analysis of the Time-to-Boundary function (TtB), which specifies the spatiotemporal proximity of the Centre of Pressure (CoP) to the stability boundaries in the regulation of posture in upright stance, is among the techniques used to better characterize postural stability in adults, but, as of now, it has not yet been introduced in developmental studies...
2017: Open Biomedical Engineering Journal
Yoko Kato, Michelle L Oyen, Graham J Burton
BACKGROUND: In the human placenta, maternal and fetal bloods exchange substances through the surface of the villous trees: the fetal blood circulates in the villous trees, around which the maternal blood circulates. The blood flows directly influence fetal growth. Stem villi, the main supports of the villous tree, have contractile cells along the axes, whose contractions are expected to influence the blood circulations in the placenta. The displacement is neither measurable nor predictable while non-invasive measurements such as umbilical Doppler waveforms are helpful to predict the histological changes of the villous trees and vascularization in the placenta...
2017: Open Biomedical Engineering Journal
Angela Agostinelli, Agnese Sbrollini, Luca Burattini, Sandro Fioretti, Francesco Di Nardo, Laura Burattini
BACKGROUND: Fetal well-being evaluation may be accomplished by monitoring cardiac activity through fetal electrocardiography. Direct fetal electrocardiography (acquired through scalp electrodes) is the gold standard but its invasiveness limits its clinical applicability. Instead, clinical use of indirect fetal electrocardiography (acquired through abdominal electrodes) is limited by its poor signal quality. OBJECTIVE: Aim of this study was to evaluate the suitability of the Segmented-Beat Modulation Method to denoise indirect fetal electrocardiograms in order to achieve a signal-quality at least comparable to the direct ones...
2017: Open Biomedical Engineering Journal
Angela Agostinelli, Ilaria Marcantoni, Elisa Moretti, Agnese Sbrollini, Sandro Fioretti, Francesco Di Nardo, Laura Burattini
BACKGROUND: Indirect fetal electrocardiography is preferable to direct fetal electrocardiography because of being noninvasive and is applicable also during the end of pregnancy, besides labor. Still, the former is strongly affected by noise so that even R-peak detection (which is essential for fetal heart-rate evaluations and subsequent processing procedures) is challenging. Some fetal studies have applied the Pan-Tompkins' algorithm that, however, was originally designed for adult applications...
2017: Open Biomedical Engineering Journal
Yu-Ping Qin, Shuang Zhang, Hai-Yan Liu, Yi-He Liu, You-Zhi Li, Xue Peng, Xiu Ma, Qi-Li Li, Xuan Huang
BACKGROUND: The galvanic coupling intra-body communication has low radiation and strong anti-interference ability, so it has many advantages in the wireless communication. METHOD: In order to analyze the effect of muscle tissue's characteristics upon the communication channel, we selected the muscle of pig buttock as the experimental sample, and used it to study the attenuation property with the galvanic coupling intra-body communication channel along the parallel direction and the transverse direction relative to the muscular fibre line as well as on the surface of destroyed muscular fibre; the study frequency ranges from 1kHz to 10MHz...
2017: Open Biomedical Engineering Journal
Tomohiro Fukui, Hiroaki Asama, Manabu Kimura, Toshiyuki Itoi, Koji Morinishi
BACKGROUND: The transposition of the great arteries (TGA) is one of the most severe congenital heart diseases. The arterial switch operation (ASO) is the preferred procedure to treat TGA. Although numerous reports have shown good results after ASOs, some patients suffer from circulatory system problems following the procedure. One reason for problems post-ASO is the local changes in the curvature and torsion of the thoracic aorta. OBJECTIVE: The influence of these geometric changes on the blood flow field needs to be investigated in detail to consider possible cardiovascular problems after an ASO...
2017: Open Biomedical Engineering Journal
Cong Wei
[This retracts the article on p. 240 in vol. 9.].
2016: Open Biomedical Engineering Journal
Cheng Kai, Zhang Denglan, Deng Jingxuan, Zhao Yijun
[This retracts the article on p. 185 in vol. 9.].
2016: Open Biomedical Engineering Journal
Jingbing Li, Yaoli Liu, Jiling Zhong
[This retracts the article on p. 131 in vol. 8.].
2016: Open Biomedical Engineering Journal
Liu Zhong-Hua, Hou Xiao-Ge, Zhao Jin-Hui, H E Le
[This retracts the article on p. 224 in vol. 9.].
2016: Open Biomedical Engineering Journal
Li Qi, Liu Ying
[This retracts the article on p. 318 in vol. 9.].
2016: Open Biomedical Engineering Journal
Hua Miao
[This retracts the article on p. 322 in vol. 9.].
2016: Open Biomedical Engineering Journal
Liu Zhong-Hua, Guo Jie
[This retracts the article on p. 282 in vol. 9.].
2016: Open Biomedical Engineering Journal
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