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Beneficial Microbes

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https://www.readbyqxmd.com/read/30406696/regulatory-t-cells-and-toll-like-receptor-2-and-4-mrna-expression-in-infants-with-colic-treated-with-lactobacillus-reuteri-dsm17938
#1
F Savino, I Galliano, M Garro, A Savino, V Daprà, P Montanari, M Bergallo
Regulatory T cells induce immune homeostasis and the expression of Toll like receptors (TLRs); subsequent inflammatory cytokine release may be involved. Recent studies have shown a microbial imbalance in the gut of colicky infants (with a prevalence of gram-negative bacteria, such as Escherichia coli), and accumulating evidence has shown the efficacy of a probiotic (Lactobacillus reuteri) in breastfed subjects, but the underlying mechanism remains undefined. The study enrolled 59 infants younger than 60 days, of whom 34 subjects had colic and 25 were healthy controls...
November 8, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/30406695/protective-effect-of-lactobacillus-reuteri-kub-ac5-against-salmonella-enteritidis-challenge-in-chickens
#2
M Nakphaichit, S Sobanbua, S Siemuang, W Vongsangnak, J Nakayama, S Nitisinprasert
Poultry is an important high-quality food and protein source for humans. However, chicken is considered a primary source of foodborne diseases, especially Salmonella Enteritidis infection. Reducing Salmonella contamination in live poultry will thus lower the risk to consumers. Our previous studies reported that Lactobacillus reuteri KUB-AC5 can produce a substance with antimicrobial activity against pathogenic bacteria, especially Salmonella. In vivo testing revealed that this strain greatly influenced the ileal microbiota by improving chicken gastrointestinal health and inhibiting certain pathogenic bacteria...
November 8, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/30406694/two-alkaline-motifs-in-the-lactobacillus-salivarius-lv72-oppa-surface-are-important-to-its-adhesin-function
#3
C Martín, S Escobedo, G Pérez-Martínez, J M Coll-Marqués, R Martín, J E Suárez, L M Quirós
Glycosaminoglycans are involved in the attachment of Lactobacillus salivarius Lv72, a strain of vaginal origin, to HeLa cell cultures, indicating that they play a fundamental role in the attachment of mutualistic bacteria to the epithelium lining cavities where the normal microbiota thrives. The bacterial OppA protein has been proposed as an adhesin involved in this adherence since, once purified, it significantly interferes with attachment of the lactobacilli to HeLa cell cultures. In this article, the role of OppA is confirmed through the determination of its location at the cell surface and its ability to promote Lactobacillus casei and Lactococcus lactis adherence to eukaryotic cell cultures upon cloning and expression of oppA in these bacteria...
November 8, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/30406693/comment-on-gut-microbiota-characterisation-in-obese-patients-before-and-after-bariatric-surgery
#4
F-G Wang, G Campisciano
No abstract text is available yet for this article.
November 8, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/30353740/lactobacillus-paracasei-k5-displays-adhesion-anti-proliferative-activity-and-apoptotic-effects-in-human-colon-cancer-cells
#5
P Chondrou, A Karapetsas, D E Kiousi, D Tsela, A Tiptiri-Kourpeti, I Anestopoulos, I Kotsianidis, E Bezirtzoglou, A Pappa, A Galanis
Lactobacillus paracasei K5 is a lactic acid bacteria (LAB) strain, isolated recently from feta-type cheese. Its probiotic potential has been demonstrated in a series of established in vitro tests. Moreover, incorporation of L. paracasei K5 as starter culture offered organoleptic and technological advantages to novel fermented food products. In the present study, further investigation of the potential probiotic activity of L. paracasei K5 was performed and its mechanisms of action were investigated. Employing quantitative analysis and confocal, fluorescent microscopy the adhesion properties of the above strain were studied...
October 24, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/30353739/bioactive-factors-secreted-by-bifidobacterium-breve-b-3-enhance-barrier-function-in-human-intestinal-caco-2-cells
#6
Y Kurose, J Minami, A Sen, N Iwabuchi, F Abe, J Xiao, T Suzuki
Intestinal barrier function is closely related to intestinal health and diseases. Recent studies demonstrate that some probiotic and commensal bacteria secrete metabolites that are capable of affecting the intestinal functions. The present study examined an enhancing effect of bioactive factors secreted by Bifidobacterium breve strain B-3 on the intestinal tight junction (TJ) barrier integrity in human intestinal Caco-2 cells. Administration of conditioned medium obtained from B. breve strain B-3 (B3CM) to Caco-2 cells for 24 h increased trans-epithelial electrical resistance (TER), a TJ barrier indicator, across their monolayers...
October 24, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/30274522/beneficial-effects-of-saccharomyces-cerevisiae-rc016-in-weaned-piglets-in-vivo-and-ex-vivo-analysis
#7
G R Garcia, C A Dogi, V L Poloni, A S Fochesato, A De Moreno de Leblanc, A M Cossalter, D Payros, I P Oswald, L R Cavaglieri
Probiotics represents an alternative to replace antibiotics as growth promoters in animal feed and are able to control enteric bacterial diseases and to improve gut immunity. Saccharomyces cerevisiae RC016 showed previously inhibition/coagregation of pathogens) and mycotoxins adsorbent ability (aflatoxin B1 , ochratoxin A and zearalenone). The aim of this work was to evaluate beneficial properties of S. cerevisiae RC016 in a non-inflammatory in vivo model in weaned piglets and in an intestinal inflammation ex vivo model induced by the mycotoxin deoxynivalenol (DON)...
October 2, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/30232908/the-role-of-adjuvant-probiotics-to-attenuate-intestinal-inflammatory-responses-due-to-cancer-treatments
#8
M Thomsen, S Clarke, L Vitetta
Chemotherapy and radiotherapy treatment regimens for gastrointestinal, peritoneal and pelvic tumours can disrupt the intestinal microbiome and intestinal epithelia. Such disturbances can provoke symptoms such as diarrhoea, nausea and vomiting. Chemotherapy and radiotherapy induced gastrointestinal toxicity aggravating intestinal microbiome dysbiosis is postulated to adversely alter the intestinal microbiome, with a consequent induced pro-inflammatory effect that disrupts the intestinal microbiome-epithelia-mucosal immunity axis...
September 20, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/30232907/systemic-immune-response-of-gnotobiotic-mice-infected-with-porcine-circovirus-type-2-after-administration-of-lactobacillus-reuteri-l26-biocenol%C3%A2
#9
D Mudroňová, V Karaffová, T Csank, J Király, V Revajová, S Gancarčíková, R Nemcová, J Pistl, Š Vilček, M Levkut
In our previous study we confirmed an antiviral activity of probiotic Lactobacillus reuteri L26 which was mediated by stimulation of local intestinal immunity. The aim of this paper was to evaluate the influence of L. reuteri L26 on the systemic immune response in gnotobiotic mice infected with porcine circovirus type 2 (PCV2). A total of 30 germ-free mice were divided into 3 groups and animals in noninfected and infected control groups (NC and IC; n=10) received sterile de Man-Rogosa-Sharpe broth for 7 days and animals in experimental group L+PCV (n=10) were inoculated with L...
September 20, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/30208728/functional-modulation-of-caecal-fermentation-and-microbiota-in-rat-by-feeding-bean-husk-as-a-dietary-fibre-supplement
#10
H Myint, H Kishi, Y Iwahashi, W Saburi, S Koike, Y Kobayashi
A feeding study using rats was conducted to evaluate the utility of lablab bean husk and soya bean husk as sources of potential prebiotic fibre. Twenty 5-week-old Sprague Dawley rats were divided into 4 groups and fed one of the following diets for 3 weeks: purified diet (AIN93 G) containing 5% cellulose (CEL), or the same diet in which cellulose was replaced by corn starch (STA), lablab bean husk (LBH), or soya bean husk (SBH). Rats were sacrificed at 8 weeks of age and caecal digesta were collected. Feed intake, body weight, anatomical parameters, and caecal ammonia level did not differ significantly among diets...
September 13, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/30198327/mind-the-gut-probiotics-in-paediatric-neurogastroenterology
#11
S Salvatore, L Pensabene, O Borrelli, M Saps, N Thapar, D Concolino, A Staiano, Y Vandenplas
The gut-brain axis has recently emerged as a key modulator of human health and the intestinal microbiome has a well-recognised pivotal role in this strong connection. The aim of this narrative review is to update and summarise the effect and clinical applicability of probiotics in paediatric neurogastroenterology. The Cochrane Database and PubMed were searched using keywords relating to different subtypes of functional gastrointestinal disorders (FGIDs) and their symptoms, those relating to the CNS and related neurological or behavioural dysfunction as well as 'probiotic' OR 'probiotics'...
September 10, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/30198326/effect-of-combined-bifidobacteria-supplementation-and-resistance-training-on-cognitive-function-body-composition-and-bowel-habits-of-healthy-elderly-subjects
#12
T Inoue, Y Kobayashi, N Mori, M Sakagawa, J-Z Xiao, T Moritani, N Sakane, N Nagai
Physical exercise exerts favourable effects on brain health and quality of life of the elderly; some of these positive health effects are induced by the modulation of microbiota composition. We therefore conducted a randomised, double blind, placebo-controlled trial that assessed whether a combination of Bifidobacterium spp. supplementation and moderate resistance training improved the cognitive function and other health-related parameters in healthy elderly subjects. Over a 12-week period, 38 participants (66-78 years) underwent resistance training and were assigned to the probiotic Bifidobacterium supplementation (n=20; 1...
September 10, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/30198325/the-beneficial-effect-of-probiotics-as-a-supplementary-treatment-in-drug-resistant-epilepsy-a-pilot-study
#13
M Gómez-Eguílaz, J L Ramón-Trapero, L Pérez-Martínez, J R Blanco
Epilepsy is a neurological disease with high global prevalence. Despite the range of drug-based treatments currently available to control the condition, one in 3 patients experiences epileptic seizures. Therapeutic alternatives for these patients include the ketogenic diet, surgery or the cerebral implantation of neurostimulators; however these are benefits with limits. The target of this study is to find a new complementary treatment for these patients, studying the effectiveness of probiotics for controlling epileptic seizures in patients with drug-resistant epilepsy...
September 10, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/30165752/effect-of-probiotic-saccharomyces-boulardii-in-experimental-giardiasis
#14
M R S Ribeiro, D R Oliveira, F M S Oliveira, M V Caliari, F S Martins, J R Nicoli, M F Torres, M E R Andrade, V N Cardoso, M A Gomes
The aim of the study was to assess the efficacy of Saccharomyces boulardii in experimental treatment of giardiasis and its impact on intestinal integrity and some functions of gerbils infected with Giardia lamblia. 28 gerbils (Meriones unguiculatus), aged 4-6 weeks, were divided into four groups: untreated and uninfected control (CT); infected with G. lamblia (IGL); treated with S. boulardii (SB); and infected with G. lamblia and treated with S. boulardii (ITSB). The SB and ITSB groups received S. boulardii 15 days prior to being infected with G...
September 18, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/30099892/probiotic-bacillus-enhance-the-intestinal-epithelial-cell-barrier-and-immune-function-of-piglets
#15
W Du, H Xu, X Mei, X Cao, L Gong, Y Wu, Y Li, D Yu, S Liu, Y Wang, W Li
Bacillus is widely used in the livestock industry. This study was designed to evaluate the effects of probiotic Bacillus amyloliquefaciens SC06 (Ba), originally isolated from soil, in piglets diet as an alternative to antibiotics (aureomycin), mainly on intestinal epithelial barrier and immune function. Ninety piglets were divided into three groups: G1 (containing 150 mg/kg aureomycin in the diet); G2 (containing 75 mg/kg aureomycin and 1×108 cfu/kg Ba in the diet); G3 (containing 2×108 cfu/kg Ba in the diet without any antibiotics)...
September 18, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/30099890/gut-bacterial-composition-in-a-mouse-model-of-parkinson-s-disease
#16
P Perez-Pardo, H B Dodiya, P A Engen, A Naqib, C B Forsyth, S J Green, J Garssen, A Keshavarzian, A D Kraneveld
The mechanism of neurodegeneration in Parkinson's disease (PD) remains unknown but it has been hypothesised that the intestinal tract could be an initiating and contributing factor to the neurodegenerative processes. In PD patients as well as in animal models for PD, alpha-synuclein-positive enteric neurons in the colon and evidence of colonic inflammation have been demonstrated. Moreover, several studies reported pro-inflammatory bacterial dysbiosis in PD patients. Here, we report for the first time significant changes in the composition of caecum mucosal associated and luminal microbiota and the associated metabolic pathways in a rotenone-induced mouse model for PD...
September 18, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/30014710/lactobacillus-acidophilus-and-clostridium-butyricum-ameliorate-colitis-in-murine-by-strengthening-the-gut-barrier-function-and-decreasing-inflammatory-factors
#17
Y Wang, Y Gu, K Fang, K Mao, J Dou, H Fan, C Zhou, H Wang
Ulcerative colitis is a type of chronic inflammation present in the intestines for which the aetiology is not yet clear. The current therapies for ulcerative colitis cannot be considered to be long-term management strategies due to their significant side effects. Therefore, it is essential to identify an alternative therapeutic strategy for ulcerative colitis. The present study focused on the evaluation of the anti-inflammatory activities of Lactobacillus acidophilus CGMCC 7282 and Clostridium butyricum CGMCC 7281...
September 18, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/29888657/oral-administration-of-bifidobacterium-bifidum-tmc3115-to-neonatal-mice-may-alleviate-ige-mediated-allergic-risk-in-adulthood
#18
R Y Cheng, J R Yao, Q Wan, J W Guo, F F Pu, L Shi, W Hu, Y H Yang, L Li, M Li, F He
This study aimed to demonstrate whether exposure to bifidobacteria during early life influences immunity and alleviates the risk of immunoglobulin E (IgE)-mediated allergies in adulthood. BALB/c neonatal mice (n=54) were administered with a lyophilised cell preparation of Bifidobacterium bifidum TMC3115 (TMC3115) for 3 weeks. Following the intervention, the mice were immunised with intraperitoneal ovalbumin (OVA). The morphology and function of the intestinal epithelium were determined using histopathological examinations...
September 18, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/29888656/lactobacillus-acidophilus-cl1285-lactobacillus-casei-lbc80r-and-lactobacillus-rhamnosus-clr2-improve-quality-of-life-and-ibs-symptoms-a-double-blind-randomised-placebo-controlled-study
#19
RANDOMIZED CONTROLLED TRIAL
K Preston, R Krumian, J Hattner, D de Montigny, M Stewart, S Gaddam
A combination of Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R and Lactobacillus rhamnosus CLR2 was compared to placebo for relief of symptoms of irritable bowel syndrome (IBS). A total of 113 subjects at 3 clinical sites were randomised in a 2:1 ratio and followed for 12 weeks. Subjects ingested either 2 capsules of active study product, containing 50×109 cfu of live organisms, or 2 placebo capsules daily. Endpoints included improvement in abdominal pain, days of pain, distention, stool consistency and frequency, quality of life (QOL), and adequate relief (AR) of IBS symptoms...
September 18, 2018: Beneficial Microbes
https://www.readbyqxmd.com/read/29888655/increased-incidence-of-necrotizing-enterocolitis-associated-with-routine-administration-of-infloran%C3%A2-in-extremely-preterm-infants
#20
E Escribano, C Zozaya, R Madero, L Sánchez, J van Goudoever, J M Rodríguez, M Sáenz de Pipaon
We aimed to evaluate the isolation of strains contained in the Infloran™ probiotic preparation in blood cultures and its efficacy in reducing necrotizing enterocolitis (NEC) and late-onset sepsis (LOS) in extremely preterm infants. Routine use of probiotics was implemented in 2008. Infants born at <28 weeks gestational age were prospectively followed and compared with historical controls (HC) born between 2005 and 2008. Data on sepsis due to any of the two probiotic strains contained in Infloran and rates of LOS and NEC were analysed...
September 18, 2018: Beneficial Microbes
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