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Beneficial Microbes

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https://www.readbyqxmd.com/read/28884590/galacto-oligosaccharides-ameliorate-dysbiotic-bifidobacteriaceae-decline-in-japanese-patients-with-type-2-diabetes
#1
M Gonai, A Shigehisa, I Kigawa, K Kurasaki, O Chonan, T Matsuki, Y Yoshida, M Aida, K Hamano, Y Terauchi
Gut microbiota affects the host's metabolism, and it is suggested that there are differences in gut microbiota composition between patients with type 2 diabetes and healthy individuals. Additionally, dysbiosis may increase the concentration of lipopolysaccharides (LPS), causing metabolic endotoxemia, which induces impaired glucose tolerance. Several studies have reported relationships between metabolic diseases and the gut microbiota; and prebiotics, such as oligosaccharides, are commonly consumed to regulate gut microbiotas in healthy individuals...
September 8, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28884589/is-there-a-role-for-modified-probiotics-as-beneficial-microbes-a-systematic-review-of-the-literature
#2
L Zorzela, S K Ardestani, L V McFarland, S Vohra
Our objective was to conduct a systematic review and meta-analysis for the use of modified (heat-killed or sonicated) probiotics for the efficacy and safety to prevent and treat various diseases. Recent clinical research has focused on living strains of probiotics, but use in high-risk patients and potential adverse reactions including bacteremia has focused interest on alternatives to the use of live probiotics. We searched MEDLINE/PubMed, Embase, Cochrane Central Register of Controlled Trials, CINAHL, Alt Health Watch, Web of Science, Scopus, PubMed, from inception to February 14, 2017 for randomised controlled trials involving modified probiotic strains...
September 8, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28856909/lactococcus-lactis-and-lactobacillus-salivarius-bgbu1-4-differently-modulate-early-immunological-response-of-wistar-rats-co-administered-with-listeria-monocytogenes
#3
J Lukic, I Jancic, N Mirkovic, B Bufan, J Djokic, M Milenkovic, J Begovic, I Strahinic, J Lozo
In the light of the increasing resistance of bacterial pathogens to antibiotics, one of the main global strategies in applied science is development of alternative treatments, which would be safe both for the host and from the environmental perspective. Accordingly, the aim of this study was to test whether two lactic acid bacteria (LAB) strains, Lactococcus lactis BGBU1-4 and Lactobacillus salivarius BGHO1, could be applied as safe supplements for Listeria infection. Two major research objectives were set: to compare the effects of BGBU1-4 and BGHO1 on early immune response in gut tissue of Wistar rats co-administered with Listeria monocytogenes ATCC19111 and next, to test how this applies to their usage as therapeutics in acute ATCC19111 infection...
August 31, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28856908/butyrate-modulating-effects-on-pro-inflammatory-pathways-in-human-intestinal-epithelial-cells
#4
A Elce, F Amato, F Zarrilli, A Calignano, R Troncone, G Castaldo, R B Canani
Butyrate acts as energy source for intestinal epithelial cells and as key mediator of several immune processes, modulating gene expression mainly through histone deacetylation inhibition. Thanks to these effects, butyrate has been proposed for the treatment of many intestinal diseases. Aim of this study was to investigate the effect of butyrate on the expression of a large series of target genes encoding proteins involved in pro-inflammatory pathways. We performed quantitative real-time-PCR analysis of the expression of 86 genes encoding proteins bearing to pro-inflammatory pathways, before and after butyrate exposure, in primary epithelial cells derived from human small intestine and colon...
August 31, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28856907/to-add-or-not-to-add-probiotics-to-infant-formulae-an-updated-systematic-review
#5
A Skórka, M Pieścik-Lech, M Kołodziej, H Szajewska
We updated evidence on the effects of the administration of probiotic-supplemented infant formulae (IF) compared with unsupplemented IF. Five databases were searched up to September 2016 for randomised controlled trials. Twenty publications were identified, including five new RCTs. Supplementation of IF with Bifidobacterium lactis Bb12, either alone or with Streptococcus thermophilus, had no effect on growth, respiratory illness, antibiotic use, stool frequency or consistency. However, there was a significant reduction in the number of episodes of gastrointestinal infections (Bb12) and a lower frequency of colic or irritability (when both strains were used)...
August 31, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28856906/effect-of-propionibacterium-acidipropionici-p169-on-the-rumen-and-faecal-microbiota-of-beef-cattle-fed-a-maize-based-finishing-diet
#6
E Azad, N Narvaez, H Derakhshani, A Y Allazeh, Y Wang, T A McAllister, E Khafipour
Direct fed microbial supplementation with lactic acid utilising bacteria (i.e. Propionibacterium acidipropionici P169) has been shown to alleviate the severity of subacute ruminal acidosis in high-grain fed beef cattle. This study was carried out to explore the impact of P169 supplementation on modulating rumen and hindgut microbiota of high-grain fed steers. Seven ruminally-canulated high-grain fed steers were randomly assigned to two treatment groups: control diet (n=3) and the same diet supplemented with P169 added at a rate of 1×10(11) cfu/head/d (n=4)...
August 31, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28856905/can-probiotics-enhance-vaccine-specific-immunity-in-children-and-adults
#7
J Y Kwak, E S N Lamousé-Smith
The growing use of probiotics by the general public has heightened the interest in understanding the role of probiotics in promoting health and preventing disease. General practitioners and specialists often receive inquiries from their patients regarding probiotic products and their use to ward off systemic infection or intestinal maladies. Enhanced immune function is among the touted health benefits conferred by probiotics but has not yet been fully established. Results from recent clinical trials in adults suggest a potential role for probiotics in enhancing vaccine-specific immunity...
August 31, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28789559/the-positive-benefit-of-lactobacillus-paracasei-ncc2461-st11-in-healthy-volunteers-with-moderate-to-severe-dandruff
#8
P Reygagne, P Bastien, M P Couavoux, D Philippe, M Renouf, I Castiel-Higounenc, A Gueniche
Dandruff is a common persistent, relapsing inflammatory condition affecting the scalp. An imbalanced proportion of the major bacterial and fungal populations colonising the scalp, a skin barrier dysfunction, and hyperseborrhoea are three main etiological factors of dandruff. The efficacy of Lactobacillus paracasei NCC 2461 ST11 (ST11) to manage dandruff and to restore a balanced scalp microbiome was assessed. Sixty healthy male volunteers aged 18 to 60 years with moderate to severe dandruff consumed on a daily basis a sachet containing ST11 (1×10(9) cfu) or a placebo for 56 days...
August 9, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28760005/evidence-based-selection-of-probiotic-strains-to-promote-astronaut-health-or-alleviate-symptoms-of-illness-on-long-duration-spaceflight-missions
#9
G L Douglas, A A Voorhies
Spaceflight impacts multiple aspects of human physiology, which will require non-invasive countermeasures as mission length and distance from Earth increases and the capability for external medical intervention decreases. Studies on Earth have shown that probiotics have the potential to improve some of the conditions that have manifested during spaceflight, such as gastrointestinal distress, dermatitis, and respiratory infections. The constraints and risks of spaceflight make it imperative that probiotics are carefully selected based on their strain-specific benefits, doses, delivery mechanisms, and relevance to likely crew conditions prior to evaluation in astronauts...
August 1, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28726510/the-effect-of-probiotic-lactobacillus-casei-shirota-on-knee-osteoarthritis-a-randomised-double-blind-placebo-controlled-clinical-trial
#10
M Lei, C Guo, D Wang, C Zhang, L Hua
Knee osteoarthritis (OA) treatment is challenging due to inefficacy and adverse effects of current medications. Probiotic treatment has been shown to promote bone metabolism, reduce pain and inflammatory responses of age-related musculoskeletal disorders, including OA. We aimed to investigate the effect of probiotic Lactobacillus casei Shirota (LcS) on patients with knee OA. 537 patients with knee OA were enrolled in this double-blind, placebo-controlled trial, who were randomised to receive skimmed milk containing either LcS or placebo daily for 6 months...
July 20, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28789560/milk-fermented-by-lactobacillus-species-from-brazilian-artisanal-cheese-protect-germ-free-mice-against-salmonella-typhimurium-infection
#11
L B Acurcio, S H C Sandes, R W Bastos, F M Sant'anna, S H S P Pedroso, D C Reis, Á C Nunes, G D Cassali, M R Souza, J R Nicoli
Ingestion of milks fermented by Lactobacillus strains showing probiotic properties is an important tool to maintain gastrointestinal health. In this study, Lactobacillus rhamnosus D1 and Lactobacillus plantarum B7, isolated from Brazilian artisanal cheese, were used as starters for the functional fermented milks to assess their probiotic properties in a gnotobiotic animal model. Male germ-free Swiss mice received a single oral dose of milk fermented by each sample, and were challenged with Salmonella Typhimurium five days afterwards...
August 24, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28726512/human-milk-oligosaccharide-categories-define-the-microbiota-composition-in-human-colostrum
#12
J Aakko, H Kumar, S Rautava, A Wise, C Autran, L Bode, E Isolauri, S Salminen
Human milk oligosaccharides (HMOs) are structurally diverse unconjugated glycans with a composition unique to each lactating mother. While HMOs have been shown to have an impact on the development of infant gut microbiota, it is not well known if HMOs also already affect milk microbial composition. To address this question, we analysed eleven colostrum samples for HMO content by high-pressure liquid chromatography and microbiota composition by quantitative PCR. Higher total HMO concentration was associated with higher counts of Bifidobacterium spp...
August 24, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28726511/how-do-probiotics-and-prebiotics-function-at-distant-sites
#13
G Reid, T Abrahamsson, M Bailey, L B Bindels, R Bubnov, K Ganguli, C Martoni, C O'Neill, H M Savignac, C Stanton, N Ship, M Surette, K Tuohy, S van Hemert
The realisation that microbes regarded as beneficial to the host can impart effects at sites distant from their habitat, has raised many possibilities for treatment of diseases. The objective of a workshop hosted in Turku, Finland, by the International Scientific Association for Probiotics and Prebiotics, was to assess the evidence for these effects and the extent to which early life microbiome programming influences how the gut microbiota communicates with distant sites. In addition, we examined how probiotics and prebiotics might affect the skin, airways, heart, brain and metabolism...
August 24, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28726509/soymilk-fermentation-by-enterococcus-faecalis-vb43-leads-to-reduction-in-the-immunoreactivity-of-allergenic-proteins-%C3%AE-conglycinin-7s-and-glycinin-11s
#14
V Biscola, A Rodriguez de Olmos, Y Choiset, H Rabesona, M S Garro, F Mozzi, J-M Chobert, M Drouet, T Haertlé, B D G M Franco
Food allergies represent a serious problem affecting human health and soy proteins rank among the most allergenic proteins from food origin. The proteolytic enzymes produced by lactic acid bacteria (LAB) can hydrolyse the major allergens present in soybean, reducing their immunoreactivity. Many studies have reported the ability of LAB to ferment soy-based products; while the majority of them focus on the improvement of the sensory characteristics and functionality of soy proteins, a lack of information about the role of lactic fermentation in the reduction of immunoreactivity of these proteins exists...
August 24, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28701082/bovine-mastitis-prevention-humoral-and-cellular-response-of-dairy-cows-inoculated-with-lactic-acid-bacteria-at-the-dry-off-period
#15
M Pellegrino, N Berardo, J Giraudo, M E F Nader-Macías, C Bogni
The use of lactic acid bacteria (LAB) in animal feed, constitute an alternative tool for bovine mastitis prevention. Previously, two LAB strains were isolated from bovine milk and selected for their probiotics properties. So far, immune response of inoculating LAB in bovine udders at dry-off period has not been investigated. The immunoglobulin isotype levels and memory cell proliferation in blood and milk of animals inoculated with Lactobacillus lactis subsp. lactis CRL1655 and Lactobacillus perolens CRL1724 at dry-off period was studied...
August 24, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28701081/gut-microbiota-dysbiosis-associated-with-glucose-metabolism-disorders-and-the-metabolic-syndrome-in-older-adults
#16
K Lippert, L Kedenko, L Antonielli, I Kedenko, C Gemeier, M Leitner, A Kautzky-Willer, B Paulweber, E Hackl
Obesity and associated metabolic disorders have become highly prevalent diseases worldwide, and the human gut microbiota, due to its influence on host energy metabolism, has been attributed an important role therein. This pilot study explores host-microbiota relationships in men and women affected by various types of glucose metabolism disorder. Among 20 individuals aged 58 to 71 years with either normal glucose tolerance, prediabetes, or type 2 diabetes mellitus the gut bacterial communities were compared based on barcoded 454 sequencing of 16S rRNA genes amplified from stool samples...
August 24, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28670908/effects-of-lactobacillus-rhamnosus-gg-on-the-maturation-and-differentiation-of-dendritic-cells-in-rotavirus-infected-mice
#17
Y Jiang, L Ye, Y Cui, G Yang, W Yang, J Wang, J Hu, W Gu, C Shi, H Huang, C Wang
Rotavirus-related diarrhoea is considered one of the most important diseases in field animal production. In addition to the classic vaccine strategy, a number of studies have utilised probiotics, such as Lactobacillus rhamnosus GG (LGG), to prevent rotavirus-induced diarrhoea. Although it has been partially revealed that Toll-like receptors (TLRs) are involved in the LGG-mediated protection against rotavirus infection, the details of the underlying immunologic mechanisms remain largely unknown. In this study, three-to-four-week-old female BALB/c mice were divided into three groups and orally administered phosphate buffered saline (PBS), PBS plus rotavirus or LGG plus rotavirus, respectively...
August 24, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28618865/streptococcus-thermophilus-ncimb-41856-ameliorates-signs-of-colitis-in-an-animal-model-of-inflammatory-bowel-disease
#18
J R Bailey, V Vince, N A Williams, T A Cogan
Treatment of inflammatory bowel disease (IBD) is mainly based on suppression of symptoms, often with numerous side effects. Trials of probiotics in IBD have frequently produced disappointing results. The majority of probiotics are unusual, since they do not require iron for growth, unlike many bacteria resident in the intestine. The IBD intestine is iron-rich due to bleeding and use of oral iron supplements; conventional probiotics would be rapidly outcompeted. We have evaluated an iron-responsive Streptococcus thermophilus strain for its potential to reduce signs of colitis...
August 24, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28618864/gut-microbiota-composition-strongly-correlates-to-peripheral-insulin-sensitivity-in-obese-men-but-not-in-women
#19
J Most, G H Goossens, D Reijnders, E E Canfora, J Penders, E E Blaak
Gut microbiota composition may play an important role in the development of obesity-related comorbidities. However, only few studies have investigated gender-differences in microbiota composition and gender-specific associations between microbiota or microbial products and insulin sensitivity. Insulin sensitivity (hyperinsulinemic-euglycemic clamp), body composition (dual energy X-ray absorptiometry), substrate oxidation (indirect calorimetry), systemic inflammatory markers and microbiota composition (PCR) were determined in male (n=15) and female (n=14) overweight and obese subjects...
August 24, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28618863/interaction-of-vaginal-lactobacillus-strains-with-hela-cells-plasma-membrane
#20
N Calonghi, C Parolin, G Sartor, L Verardi, B Giordani, G Frisco, A Marangoni, B Vitali
Vaginal lactobacilli offer protection against recurrent urinary and vaginal infections. The precise mechanisms underlying the interaction between lactobacilli and the host epithelium remain poorly understood at the molecular level. Deciphering such events can provide valuable information on the mode of action of commensal and probiotic bacteria in the vaginal environment. We investigated the effects exerted by five Lactobacillus strains of vaginal origin (Lactobacillus crispatus BC1 and BC2, Lactobacillus gasseri BC9 and BC11 and Lactobacillus vaginalis BC15) on the physical properties of the plasma membrane in a cervical cell line (HeLa)...
August 24, 2017: Beneficial Microbes
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