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Beneficial Microbes

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https://www.readbyqxmd.com/read/28504581/bacillus-coagulans-gbi-30-6086-increases-plant-protein-digestion-in-a-dynamic-computer-controlled-in-vitro-model-of-the-small-intestine-tim-1
#1
D Keller, R Van Dinter, H Cash, S Farmer, K Venema
The aim of this study was to assess the potential of the probiotic Bacillus coagulans GBI-30, 6086 [GanedenBC(30)] (BC30) to aid in protein digestion of alimentary plant proteins. To test this, three plant proteins, from pea, soy and rice, were digested in a validated in vitro model of the stomach and small intestine (TIM-1) in the absence and in the presence of BC30. Samples were taken from the TIM-1 fractions that mimic uptake of amino acids by the host and analysed for α-amino nitrogen (AAN) and total nitrogen (TN)...
May 15, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28504580/intragastric-administration-of-lactobacillus-casei-bl23-induces-regulatory-foxp3-ror%C3%AE-t-t-cells-subset-in-mice
#2
N G Cortes-Perez, D Lozano-Ojalvo, M A Maiga, S Hazebrouck, K Adel-Patient
Many studies have highlighted the immunomodulatory properties of the probiotic strain Lactobacillus casei BL23. Recently, we demonstrated the ability of this strain to modulate the Th2-oriented immune response in a mouse model of cow's milk allergy based on the induction of a Th17-biased immune response. The probiotic function of L. casei has been also linked to gut-microbiota modifications which could been potentially involved in the immune regulation; however, its precise mechanism of action remains poorly understood...
May 15, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28504579/exopolysaccharide-producing-streptococcus-thermophilus-crl1190-reduces-the-inflammatory-response-caused-by-helicobacter-pylori
#3
G Marcial, J Villena, G Faller, A Hensel, G Font de Valdéz
This work evaluated the ability of the probiotic Streptococcus thermophilus CRL1190 strain and its exopolysaccharides to adhere to gastric mucosa. Probiotic bacteria attachment to the human stomach epithelium was confirmed in human stomach tissue samples and the gastric epithelial cell line AGS. In addition, it was demonstrated that S. thermophilus CRL1190 strain reduced Helicobacter pylori adhesion and attenuated inflammatory response in AGS cells. This is the first demonstration of the capacity of S. thermophilus CRL1190 to adhere to the stomach gastric mucosa, and improve protection against H...
May 15, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28504578/effects-of-dietary-chitosan-on-growth-lipid-metabolism-immune-response-and-antioxidant-related-gene-expression-in-misgurnus-anguillicaudatus
#4
J Yan, C Guo, M A O Dawood, J Gao
This study was performed to evaluate the effects of dietary chitosan supplementation on growth performance, lipid metabolism, gut microbial, antioxidant status and immune responses of juvenile loach (Misgurnus anguillicaudatus). Five experimental diets were formulated to contain graded levels of chitosan (0 (control), 0.5, 1, 2 and 5% CHI) for 50 days. Results of the present study showed that body weight gain was significantly higher in fish fed chitosan supplemented diets in dose dependent manner than control group...
May 15, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28504577/lactobacillus-fermentum-im12-attenuates-inflammation-in-mice-by-inhibiting-nf-%C3%AE%C2%BAb-stat3-signalling-pathway
#5
S-M Lim, H M Jang, S-E Jang, M J Han, D-H Kim
In the present study, we isolated Lactobacillus fermentum IM12 from human gut microbiota, which strongly inhibited interleukin (IL)-6 expression and STAT3 activation in lipopolysaccharide (LPS)-stimulated murine peritoneal macrophages, and examined its anti-inflammatory effect in mice with carrageenan-induced hind-paw oedema (CIE) or 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis (TIC). Oral administration of IM12 (0.2×10(9), 1×10(9) or 5×10(9) cfu/mouse, once a day for 3 days) in mice with CIE significantly suppressed the increase of oedema volume and thickness, as well as myeloperoxidase activity and IL-6, IL-17, NO, and prostaglandin E2 levels in the carrageenan-stimulated paw...
May 15, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28504576/is-the-role-of-human-female-reproductive-tract-microbiota-underestimated
#6
D Kamińska, M Gajecka
An issue that is currently undergoing extensive study is the influence of human vaginal microbiota (VMB) on the health status of women and their neonates. Healthy women are mainly colonised with lactobacilli such as Lactobacillus crispatus, Lactobacillus jensenii, and Lactobacillus iners; however, other bacteria may be elements of the VMB, particularly in women with bacterial vaginosis. The implementation of culture-independent molecular methods in VMB characterisation, especially next-generation sequencing, have provided new information regarding bacterial diversity in the vagina, revealing a large number of novel, fastidious, and/or uncultivated bacterial species...
May 15, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28504575/alleviation-of-enterotoxigenic-escherichia-coli-challenge-by-recombinant-lactobacillus-plantarum-expressing-a-faeg-and-dc-targeting-peptide-fusion-protein
#7
G Yang, Y Jiang, P Tong, C Li, W Yang, J Hu, L Ye, W Gu, C Shi, B Shan, C Wang
FaeG is the major subunit of K88 fimbriae. These cell surface attachments are considered to be the major virulence factor of enterotoxigenic Escherichia coli (ETEC), which causes diarrhoea in piglets. The use of dendritic cell-targeting peptide (DCpep) has been demonstrated to be an effective approach to enhance the immunity of vaccines. Lactobacillus plantarum is an attractive candidate for oral vaccination owing to its beneficial effects and safety. In this study, L. plantarum was employed to deliver a FaeG-DCpep fusion antigen, and the immune response in mice was evaluated...
May 15, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28504574/gut-dysbiosis-following-c-section-instigates-higher-colonisation-of-toxigenic-clostridium-perfringens-in-infants
#8
R Nagpal, H Tsuji, T Takahashi, K Nomoto, K Kawashima, S Nagata, Y Yamashiro
Herein we investigated the intestinal carriage of α-toxigenic and enterotoxigenic Clostridium perfringens during infancy, focusing on its association with other gut microbes and mode of delivery and feeding. Faecal samples from 89 healthy term infants were collected at age 7 days, 1 month, 3 months, 6 months and 3 years. C. perfringens was quantified by qPCR; other gut bacteria were quantified by reverse-transcription-qPCR. Alpha-toxigenic C. perfringens was detected in 3.4% infants at day 7 but was present in 35-40% infants at subsequent time-points, with counts ranging from 10(3)-10(7) cells/g faeces...
May 15, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28504568/lactobacillus-rhamnosus-crl1505-nasal-administration-improves-recovery-of-t-cell-mediated-immunity-against-pneumococcal-infection-in-malnourished-mice
#9
N Barbieri, M Herrera, S Salva, J Villena, S Alvarez
Immunobiotic lactic acid bacteria have become an interesting alternative for the prevention of respiratory infections. Previously, we demonstrated that the nasal administration of Lactobacillus rhamnosus CRL1505, during repletion of malnourished mice, resulted in diminished susceptibility to the challenge with the respiratory pathogen Streptococcus pneumoniae. Considering the known alterations induced by malnutrition on T lymphocytes and the importance of this cell population on the protection against respiratory pathogens, we aimed to study the effect of L...
May 15, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28504567/effects-of-lactobacillus-casei-ccfm419-on-insulin-resistance-and-gut-microbiota-in-type-2-diabetic-mice
#10
X Li, E Wang, B Yin, D Fang, P Chen, G Wang, J Zhao, H Zhang, W Chen
The antidiabetic effect of Lactobacillus is increasingly recognized worldwide. In this research, the hypoglycemic activity of Lactobacillus casei CCFM419 was investigated in mice with high-fat and low-dose streptozotocin induced type 2 diabetes. Oral L. casei CCFM419 administration favourably regulated blood glucose balance, increased glucose tolerance and protected islets in the diabetic mice, accompanied by an improvement in lipid metabolism. The homeostasis model of insulin resistance, insulin level and insulin tolerance test and mRNA expression of PI3K/Akt signalling pathway indexes revealed that L...
May 15, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28504566/influence-of-lactobacillus-reuteri-l26-biocenol%C3%A2-on-immune-response-against-porcine-circovirus-type-2-infection-in-germ-free-mice
#11
V Karaffová, T Csank, D Mudroňová, J Király, V Revajová, S Gancarčíková, R Nemcová, J Pistl, Š Vilček, M Levkut
Probiotic bacteria are frequently used for prevention of bacterial infections of the gastrointestinal tract, but there are only limited studies on their efficacy against viral gut infections in animals. The aim of this study was to investigate the effect of probiotic Lactobacillus reuteri L26 Biocenol(TM) on the innate and adaptive immune responses in germ-free Balb/c mice, experimentally infected by porcine circovirus type 2 (PCV2), which confers immunosuppressive effect. A total of 30 six-week-old female mice were divided into 3 groups and animals in experimental group LPCV (n=10) were inoculated with L...
May 15, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28441886/differences-between-live-and-heat-killed-bifidobacteria-in-the-regulation-of-immune-function-and-the-intestinal-environment
#12
H Sugahara, R Yao, T Odamaki, J Z Xiao
Probiotics are live microorganisms that confer a health benefit on the host, such as improvement of the intestinal environment, modulation of immune function and energy metabolism. Heat-killed probiotic strains have also been known to exhibit some physiological functions; however, the differences between live and heat-killed probiotics have not been well elucidated. In this study, we investigated the differences between live and heat-killed Bifidobacterium breve M-16V, a probiotic strain, in the regulation of immune function, intestinal metabolism and intestinal gene expression of the host using gnotobiotic mouse model and omics approaches...
April 26, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28441885/lactobacillus-plantarum-l9-but-not-lactobacillus-acidophilus-la-reduces-tumour-necrosis-factor-induced-bacterial-translocation-in-caco-2-cells
#13
B Wang, J Chen, S Wang, X Zhao, G Lu, X Tang
Translocation of bacteria across the intestinal barrier is important in the pathogenesis of systemic sepsis and multiple organ dysfunction syndromes. Inflammatory cytokines increase paracellular permeability that allows increased luminal bacteria to translocate across mucosal epithelium and further deteriorate the gut barrier. In order to reduce this risk, the prophylactic use of probiotics has been recently addressed. In this paper, we investigate the protective role toward tumour necrosis factor (TNF)-α induced non-pathogenic Escherichia coli translocation across Caco-2 monolayers of Lactobacillus strains...
April 26, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28403650/a-new-contribution-to-the-history-of-probiotics
#14
G A Calatayud, J E Suárez
No abstract text is available yet for this article.
April 13, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28403649/a-survey-of-probiotic-use-practices-among-patients-at-a-tertiary-medical-centre
#15
K Draper, C Ley, J Parsonnet
Probiotic use has skyrocketed in recent years. Little is known, however, about patient knowledge and practices regarding probiotic use, especially in the context of antibiotic use. An invitation to complete a short, anonymous, electronic survey was sent by email to 965 patients at a tertiary medical centre in California who had agreed to be contacted for participation in research studies. Questions were asked about both probiotic and antibiotic use in the prior three months. Of 333 survey respondents, 55% had recently used probiotics, including food products and/or supplements (90 and 60% of probiotic users, respectively)...
April 13, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28343402/probiotic-administration-improves-sperm-quality-in-asthenozoospermic-human-donors
#16
D G Valcarce, S Genovés, M F Riesco, P Martorell, M P Herráez, D Ramón, V Robles
The objective of this study is to analyse the effect of the ingestion of two selected antioxidant probiotics strains (Lactobacillus rhamnosus CECT8361 and Bifidobacterium longum CECT7347) on sperm quality parameters in asthenozoospermic males after three and six weeks of administration. Nine asthenozoospermic men without any medical treatment under similar diet conditions participated in the study. The quality of individual sperm samples was evaluated before (previous to ingestion), during (after 3 and 6 weeks of ingestion) and after probiotic administration (3 and 6 weeks after finishing the treatment)...
March 27, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28343401/effect-of-probiotic-on-innate-inflammatory-response-and-viral-shedding-in-experimental-rhinovirus-infection-a-randomised-controlled-trial
#17
R B Turner, J A Woodfolk, L Borish, J W Steinke, J T Patrie, L M Muehling, S Lahtinen, M J Lehtinen
Ingestion of probiotics appears to have modest effects on the incidence of viral respiratory infection. The mechanism of these effects is not clear; however, there is evidence from animal models that the probiotic may have an effect on innate immune responses to pathogens. The purpose of this randomised, placebo-controlled study was to determine the effect of administration of Bifidobacterium animalis subspecies lactis Bl-04 on innate and adaptive host responses to experimental rhinovirus challenge. The effect on the response of chemokine (C-X-C motif) ligand 8 (CXCL8) to rhinovirus infection was defined as the primary endpoint for the study...
March 27, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28299945/in-vitro-and-in-vivo-cholesterol-lowering-ability-of-lactobacillus-pentosus-kf923750
#18
F Bendali, K Kerdouche, S Hamma-Faradji, D Drider
Lactobacillus pentosus KF923750 was characterised for probiotic related properties and then characterised for cholesterol uptake in vitro as well as in vivo using rabbits fed a high-cholesterol diet. The survival percentage of L. pentosus KF923750 was 100% at pH 3, 52.18% at pH 2 and 36.21% at pH 2 plus pepsin. Similarly, this strain appeared resistant to bile (0.1% [98.42%], 0.3% [88.52%], 0.5% [75.60%] and 1% [71.15%]), after 4 h exposure. Moreover, L. pentosus KF923750 controlled growth of Escherichia coli ATCC 25922 and Staphylococcus aureus ATCC 25923 through the production of a bacteriocin-like inhibitory substance and anti-adhesive capabilities...
March 16, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28299944/streptococcus-thermophilus-fermented-milk-reduces-serum-mda-ldl-and-blood-pressure-in-healthy-and-mildly-hypercholesterolaemic-adults
#19
M Ito, S Kusuhara, W Yokoi, T Sato, H Ishiki, S Miida, A Matsui, K Nakamori, C Nonaka, K Miyazaki
Low-density lipoprotein (LDL)-cholesterol, malondialdehyde-modified low-density lipoprotein (MDA-LDL), MDA-LDL/LDL-cholesterol in serum, and blood pressure are considered useful risk markers of cardiovascular diseases. This study aimed to examine whether a fermented milk containing Streptococcus thermophilus YIT 2001 (ST), which has high anti-oxidative activity, would benefit healthy and mildly hyper-LDL-cholesterolaemic adults via a randomised, double-blind, placebo-controlled trial. ST-fermented milk or non-fermented placebo milk (PC) was consumed once a day for 12 weeks by 29 and 30 subjects, respectively, with average serum LDL-cholesterol levels of about 140 mg/dl...
March 16, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28548573/inulin-type-fructan-degradation-capacity-of-clostridium-cluster-iv-and-xiva-butyrate-producing-colon-bacteria-and-their-associated-metabolic-outcomes
#20
F Moens, L De Vuyst
Four selected butyrate-producing colon bacterial strains belonging to Clostridium cluster IV (Butyricicoccus pullicaecorum DSM 23266(T) and Faecalibacterium prausnitzii DSM 17677(T)) and XIVa (Eubacterium hallii DSM 17630 and Eubacterium rectale CIP 105953(T)) were studied as to their capacity to degrade inulin-type fructans and concomitant metabolite production. Cultivation of these strains was performed in bottles and fermentors containing a modified medium for colon bacteria, including acetate, supplemented with either fructose, oligofructose, or inulin as the sole energy source...
May 30, 2017: Beneficial Microbes
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