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Biopreservation and Biobanking

Ma'n H Zawati, Anne Marie Tassé, Maimuna Mendy, Elodie Caboux, Michael Lang
As biobanking research in low- and middle-income countries (LMICs) continues to grow, novel legal and policy considerations have arisen. Also, while an expansive literature has developed around these issues, the views and concerns of individual researchers in these contexts have been less actively studied. These meeting notes aim to contribute to the growing literature on biobanking in LMICs by communicating a number of challenges and opportunities identified by biobank researchers themselves. Specifically, we describe concerns that emerge in consent and access policy domains...
April 18, 2018: Biopreservation and Biobanking
Tamsin Tarling, Zisis Kozlakidis, Brent Schacter, Sheila O'Donoghue
No abstract text is available yet for this article.
March 22, 2018: Biopreservation and Biobanking
Jim Vaught
No abstract text is available yet for this article.
March 15, 2018: Biopreservation and Biobanking
Ghiath Alahmad, Kris Dierickx
Research biobanks can offer great benefits for science and healthcare. However, many ethical challenges arise from their use. These challenges have different perspectives in Muslim countries when research biobanks are created. We propose principles for good practice related to the research biobanks in Islamic countries, focusing on issues related to confidentiality, informed consent, children's participation, and others. These issues were explored according to Islamic fatwas and Usul Al Fiqh, and we provide principles for good practice for policy makers involved in the creation of research biobanks, researchers, and anyone who has to deal with stored tissue specimens taken from Muslims...
March 13, 2018: Biopreservation and Biobanking
Kimberly White, Peixin Yang, Ling Li, Amna Farshori, Alexandre E Medina, Horst Ronald Zielke
Brain tissue from 1068 donors was analyzed for RNA quality as a function of postmortem interval (PMI) and years in storage. Approximately 83% of the cortical and cerebellar samples had an RNA integrity number (RIN) of 6 or greater, indicating their likely suitability for real-time quantitative polymerase chain reaction research. The average RIN value was independent of the PMI, up to at least 36 hours. The RNA quality for specific donated brains could not be predicted based on the PMI. Individual samples with a low PMI could have a poor RIN value, while a sample with a PMI over 36 hours may have a high RIN value...
March 2, 2018: Biopreservation and Biobanking
Peggy Manders, Tessa M A Peters, Ariaan E Siezen, Iris A L M van Rooij, Roger Snijder, Dorine W Swinkels, Gerhard A Zielhuis
INTRODUCTION: Current guidelines for clinical biobanking have a strong focus on obtaining, handling, and storage of biospecimens. However, to allow for research tying biomarker analysis to clinical decision making, there should be more focus on collection of data on donor characteristics. Therefore, our aim was to develop a stepwise procedure to define a framework as a tool to help start the data collection process in clinical biobanking. MATERIALS AND METHODS: The Radboud Biobank (RB) is a central clinical biobanking facility designed in accordance with the standards set by the Parelsnoer Institute, a Dutch national biobank originally initiated with eight different disease cohorts...
February 13, 2018: Biopreservation and Biobanking
Daniel Simeon-Dubach, Zisis Kozlakidis
No abstract text is available yet for this article.
February 2, 2018: Biopreservation and Biobanking
Koh Furuta, Clare M Allocca, Brent Schacter, Marianna J Bledsoe, Nilsa C Ramirez
Recent advances in biotechnology are making it possible to advance science and improve healthcare with increasing speed and precision. Biobanking, as a foundation of the biotechnology infrastructure, is critical to the assurance of quality for many of the key components for these advancing technologies in both the human and nonhuman domains. Biobanking must advance to support the increased complexity and required precision needs of biological resources. Standards development can provide an important link for the research and development community by providing tools to ensure quality, fitness-for-purpose, and reproducibility in biobanking...
February 2, 2018: Biopreservation and Biobanking
Lori D Campbell, Jonas J Astrin, Yvonne DeSouza, Judith Giri, Ashokkumar A Patel, Melissa Rawley-Payne, Amanda Rush, Nicole Sieffert
An increased need for specimens of reliable and consistent quality for research purposes requires the development of standardized policies and practices for the collection, handling, storage, retrieval, and distribution of specimens and specimen-related data. Providers of specimen resources should strive to incorporate new technologies and state-of-the-science approaches and thus ensure the availability of fit-for-purpose research specimens. Strategies to achieve quality outcomes and performance improvements often include adherence to established standards and implementation of best practices...
February 2, 2018: Biopreservation and Biobanking
Fay Betsou, Roberto Bilbao, Jamie Case, Rodrigo Chuaqui, Judith Ann Clements, Yvonne De Souza, Annemieke De Wilde, Jörg Geiger, William Grizzle, Fiorella Guadagni, Elaine Gunter, Stacey Heil, Michael Kiehntopf, Iren Koppandi, Sabine Lehmann, Loes Linsen, Jacqueline Mackenzie-Dodds, Rocio Aguilar Quesada, Riad Tebbakha, Teresa Selander, Katheryn Shea, Mark Sobel, Stella Somiari, Demetri Spyropoulos, Mars Stone, Gunnel Tybring, Klara Valyi-Nagy, Lalita Wadhwa
No abstract text is available yet for this article.
January 29, 2018: Biopreservation and Biobanking
Jesús García-Martínez, Daniel López Lacomba, Angel Castaño Pascual
The conservation of microorganisms is essential for their in-depth study. However, today's most widely used conservation methods, based on the use of distilled water, soil, oils, or silica, do not guarantee the stability of fungal cells, especially dermatophytes. This problem led us to evaluate the conservation capacity of a cryogenic vials system containing glass beads covered in a cryopreservant hypertonic solution as an alternative method of storage of fungal cells at -80°C. Up to 570 strains of fungi belonging to 27 different species, isolated from clinical samples, were inoculated into cryotubes containing 25 glass beads covered in a cryopreserving hypertonic solution...
January 25, 2018: Biopreservation and Biobanking
Seyedeh Zeynab Sadr, Roya Fatehi, Saman Maroufizadeh, Christiani Andrade Amorim, Bita Ebrahimi
In vitro culture of ovarian follicles is a new technique in reproductive technology, which helps in understanding the process of folliculogenesis. The in vitro culture of follicles could be carried out using three-dimensional (3D) natural scaffolds that mimic the ovarian tissue stroma. Selection of the right matrix and culture media in these scaffolds could increase the survival and maturation of the follicles. In this work, the applicability of matrigel-alginate (MA) and fibrin-alginate (FA) 3D scaffolds for folliculogenesis was assessed...
April 2018: Biopreservation and Biobanking
Maksim V Puzanov, Liudmila B Vasilyeva, Polina V Popova, Elena N Grineva, Renata I Dmitrieva
It is widely accepted that endothelial dysfunction (ED) is a common feature and a risk factor for cardiovascular diseases and metabolic disorders. Cultures of human umbilical vein endothelial cells (HUVECs) are routinely used in cell-based models to study in vitro molecular and cellular mechanisms of development of different aspects of ED. The methods of the HUVEC extraction and expansion are well developed and standardized. However, when large collections of samples are needed for certain projects, or when samples from a rare population of patients should be collected for future experimental use, HUVEC samples should be transferred to a biobank to be saved in liquid nitrogen for a long period of time until the required collection is completed...
April 2018: Biopreservation and Biobanking
Petr Holub, Florian Kohlmayer, Fabian Prasser, Michaela Th Mayrhofer, Irene Schlünder, Gillian M Martin, Sara Casati, Lefteris Koumakis, Andrea Wutte, Łukasz Kozera, Dominik Strapagiel, Gabriele Anton, Gianluigi Zanetti, Osman Ugur Sezerman, Maimuna Mendy, Dalibor Valík, Marialuisa Lavitrano, Georges Dagher, Kurt Zatloukal, GertJan B van Ommen, Jan-Eric Litton
The known challenge of underutilization of data and biological material from biorepositories as potential resources for medical research has been the focus of discussion for over a decade. Recently developed guidelines for improved data availability and reusability-entitled FAIR Principles (Findability, Accessibility, Interoperability, and Reusability)-are likely to address only parts of the problem. In this article, we argue that biological material and data should be viewed as a unified resource. This approach would facilitate access to complete provenance information, which is a prerequisite for reproducibility and meaningful integration of the data...
April 2018: Biopreservation and Biobanking
Sepideh Jalilzadeh-Tabrizi, Younes Pilehvar-Soltanahmadi, Effat Alizadeh, Shahriar Alipour, Mehdi Dadashpour, Kazem Nejati-Koshki, Nosratollah Zarghami
BACKGROUND: Emu oil (EO) with anti-inflammatory, antioxidative, and wound healing properties can be blended for preparing bioactive nanofibrous scaffold. Adipose tissue-derived stem cells (ADSCs) are promising candidates for tissue engineering, and preserving their stemness potential is vital for further therapeutic applications. AIM: The aim of this study was to fabricate EO-blended nanofiber and investigate its effect on proliferation, survival, and stemness preservation of ADSCs...
April 2018: Biopreservation and Biobanking
Shannon J McCall, Philip A Branton, Victoria M Blanc, Sarah M Dry, Julie M Gastier-Foster, James H Harrison, Scott D Jewell, Rajesh C Dash, Rebecca C Obeng, Joan Rose, Dawna L Mateski, Albi Liubinskas, James A Robb, Nilsa C Ramirez, Kathi Shea
The College of American Pathologists (CAP) developed the Biorepository Accreditation Program (BAP) in 2012. This program integrates best practices from the International Society for Biological and Environmental Biorepositories, the National Cancer Institute, the Organisation for Economic Cooperation and Development, the Center for Medicare and Medicaid Services, and the CAP Laboratory Accreditation Program. The goal of this elective program is to provide requirements for standardization in biorepository processes that will result in high-quality specimens that can be used to support research, drug discovery, and personalized medicine...
February 2018: Biopreservation and Biobanking
Sheila O'Donoghue, Lise Matzke, Peter Watson
No abstract text is available yet for this article.
February 2018: Biopreservation and Biobanking
Fay Betsou
No abstract text is available yet for this article.
February 2018: Biopreservation and Biobanking
Zisis Kozlakidis
No abstract text is available yet for this article.
February 2018: Biopreservation and Biobanking
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