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Biopreservation and Biobanking

Haiyan Li, Mingyu Ni, Peng Wang, Xiaomin Wang
The development of biomedical research urgently needs the support of a large number of high-quality clinical biospecimens. Therefore, human biobanks at different levels have been established successively in China and other countries at a significantly increasing pace in recent years. To better understand the general current state of clinical biobanks in China, we surveyed 42 clinical biobanks based in hospitals and collected information involving their management systems, sharing mechanisms, quality control systems, and informational management systems using closed questionnaire methods...
January 12, 2017: Biopreservation and Biobanking
Danielle A Bourque, Amanda M Naaum, Dan L Distel, Robert H Hanner
No abstract text is available yet for this article.
January 12, 2017: Biopreservation and Biobanking
Sergii Boryshpolets, Denisa Sochorová, Marek Rodina, Otomar Linhart, Borys Dzyuba
In the present study, we examined various freezing protocols, effects of controlled seeding, and changes in cooling rate and determined the endpoint (temperature at which sample could be plugged into liquid nitrogen (LN) without visible effect on survival rate after thawing) to reveal the relative importance of each different stage of cooling on freezing success during cryobanking of carp sperm. Sperm samples from different individual carp males were frozen in 0.5 mL straws by conventional freezing. Cooling rates were determined by monitoring the sample's internal temperature...
January 10, 2017: Biopreservation and Biobanking
Yufang Li, Gang Zhao, S M Chapal Hossain, Fazil Panhwar, Wenyu Sun, Fei Kong, Chuanbao Zang, Zhendong Jiang
Biobanking of organs by cryopreservation is an enabling technology for organ transplantation. Compared with the conventional slow freezing method, vitreous cryopreservation has been regarded to be a more promising approach for long-term storage of organs. The major challenges to vitrification are devitrification and recrystallization during the warming process, and high concentrations of cryoprotective agents (CPAs) induced metabolic and osmotic injuries. For a theoretical model based optimization of vitrification, thermal properties of CPA solutions are indispensable...
January 4, 2017: Biopreservation and Biobanking
Helder M Souza, Lúcia C P Arruda, Millena M Monteiro, Igor H A V Nery, Robespierre A J Araújo Silva, André M Batista, Maria Madalena Pessoa Guerra
The addition of antioxidants to semen cryopreservation extenders has been employed for combating oxidative damage. This work aimed to evaluate the addition of carotenoid canthaxanthin to a cryopreservation extender of ram semen. Three breeder rams were used and, after semen collection, with 48-hour intervals between collection, the samples were included in the pool formation (n = 6). The experimental groups comprised 0 (control), 0.1, 1, 10, and 25 μM of canthaxanthin. After thawing (37°C/30 s) and incubation at 37°C for 2 hours, semen aliquots from each group were evaluated for sperm kinetics (CASA), the integrity of the plasma and acrosomal membranes (iPAM), intracellular reactive oxygen species (ROS) production, and lipid peroxidation (LPO) by flow cytometry associated with the image...
December 22, 2016: Biopreservation and Biobanking
Marika Doucet, Karl Friedrich Becker, Jens Björkman, Jacques Bonnet, Bruno Clément, Maria-Grazia Daidone, Charles Duyckaerts, Gilles Erb, Helmuth Haslacher, Paul Hofman, Berthold Huppertz, Christophe Junot, Joakim Lundeberg, Andres Metspalu, Marialuisa Lavitrano, Jan-Eric Litton, Helen Moore, Manuel Morente, Ben-Youssef Naimi, Uwe Oelmueller, Bill Ollier, Barbara Parodi, Liangliang Ruan, Giorgio Stanta, Paola Turano, Jim Vaught, Peter Watson, H-Erich Wichmann, Martin Yuille, Myriam Zaomi, Kurt Zatloukal, Georges Dagher
No abstract text is available yet for this article.
December 19, 2016: Biopreservation and Biobanking
Reinhard M K Thasler, Andreas J Berghammer, Thomas Kirchner, Julia Slotta-Huspenina, Karl-Friedrich Becker, Tobias Schiergens, Wolfgang E Thasler, Heinz Erich Wichmann
No abstract text is available yet for this article.
December 19, 2016: Biopreservation and Biobanking
Alison Parry-Jones, Jarle Hansen, Daniel Simeon-Dubach, Roger Bjugn
All organizations are subject to risk and uncertainty. Adverse events may disrupt normal organizational activity and may even cause complete failure of business operations. Biorepositories are also at risk and there have been instances where multiple samples or entire collections have been destroyed. Biobank guidelines accordingly recommend the establishment of contingency plans to reduce risk to an acceptable level. In this review article, we will use general theory on risk management and illustrate how such principles can be used to establish a practical crisis management plan for any biobank organization...
December 15, 2016: Biopreservation and Biobanking
Rentao Yu, Yunjie Dan, Xiaomei Xiang, Yi Zhou, Xuemei Kuang, Ge Yang, Yulan Tang, Mingdong Liu, Weilong Kong, Wenting Tan, Guohong Deng
BACKGROUND: Serum samples are widely used in clinical research, but a comprehensive research of the stability of parameters relevant to chronic hepatitis and the effect of a relatively long-term (up to 10 years) storage on the stability have rarely been studied. AIMS: To investigate the stability of chronic hepatitis-related parameters in serum samples after long-term storage. MATERIALS AND METHODS: The storage stability of common clinical parameters such as total bile acid (TBA), total bilirubin (TBIL), potassium, cholesterol, and protein parameters such as alanine aminotransferase (ALT), creatine kinase (CK), γ-glutamyltransferase (GGT), albumin, high-density lipoprotein (HDL) and also hepatitis B virus (HBV) DNA, hepatitis C virus (HCV) RNA, hepatitis B surface antigen (HBsAg), and chemokine (C-X-C motif) ligand 10 (CXCL10) were tested in serum samples after storing at -20°C or -70°C for 1, 2, 3, 7, 8, and 10 years...
December 13, 2016: Biopreservation and Biobanking
Daniel Simeon-Dubach, Kirstin Goldring, Marianne K Henderson
No abstract text is available yet for this article.
December 12, 2016: Biopreservation and Biobanking
Jenna van Draanen, Pamela Davidson, Helene Bour-Jordan, LeeAnna Bowman-Carpio, David Boyle, Steve Dubinett, Brian Gardner, Jachael Gardner, Courtney McFall, Dan Mercola, Terry Nakazono, Stephanie Soares, Hubert Stoppler, Margaret Tempero, Scott Vandenberg, Yu-Jui Yvonne Wan, Sarah Dry
INTRODUCTION: Biosamples and associated clinical data accelerate translational and clinical research discoveries. A lack of high quality biosamples both stalls projects and limits research advances. In this study, we targeted a wide audience of University of California (UC) biobanking stakeholders who were either involved with the collection or the utilization of biosamples to assess the scope of their biobanking activities and their interest in virtual biobanking or cooperating in the formation of the UC-wide biorepository...
December 8, 2016: Biopreservation and Biobanking
John G Day, Simon Tytor, Jenny Egardt, Monica Applegren, Cecilia Rad-Menéndez, Olga Chepurnova, Wim Vyverman, Anna Godhe
Modern genomic and metabolomic tools have provided the possibility of generating and interrogating large datasets that can provide answers to previously imponderable taxonomic, evolutionary, ecological, and physiological questions. However, the curatorial tools needed to provide and maintain the relevant biological resources on which new knowledge can be built have not kept pace with this meteoric rise in scientific capacity, its associated activity, or the huge increase in published science. The availability of biological material of guaranteed identity and quality in Biological Resource Centers is fundamental for scientific research, but it crucially depends on there being adequate preservation/maintenance methods that are capable of ensuring phenotypic, genotypic, and functional security of the biological material(s)...
November 29, 2016: Biopreservation and Biobanking
Mirella Ciaburri, Mariarosaria Napolitano, Elena Bravo
Worldwide, the sustainability of public health systems is challenged by the increasing number and cost of personalized therapies. Quality biological samples stored in biobanks are essential for the provision of appropriate health services and also act as a reservoir for the development of precision medicine and biotechnological innovation. Economic sustainability is a crucial factor in the maintenance of biobanking activities. Traditionally, management of biobanking is performed by health researchers and/or clinicians whose knowledge of economic issues is inadequate...
November 29, 2016: Biopreservation and Biobanking
Kevin McCluskey
Formal living collections have unique characteristics that distinguish them from other types of biorepositories. Comprising diverse resources, microbe culture collections, crop and biodiversity plant germplasm collections, and animal germplasm repositories are commonly allied with specific research communities or stakeholder groups. Among living collections, microbial culture collections have very long and unique life histories, with some being older than 100 years. Regulatory, financial, and technical developments have impacted living collections in many ways...
November 21, 2016: Biopreservation and Biobanking
Tony Brown, Devon D Kelly, Suzanne Vercauteren, William H Wilson, Alexander Werner
As guest editors of this sustainability issue of Biopreservation and Biobanking focused on business planning, utilization, and marketing, we invited a number of experts from different sectors of the biobanking arena to provide their views on business planning issues. Each expert was asked to provide a brief background statement on their biobanks, to build a context to understand their answers to the sustainability questions. We hope that these insights and experiences can provide valuable considerations and ideas for other biobanks who wish to develop or refine their own business plans, measure their utilization rates, and work toward financial sustainability...
November 21, 2016: Biopreservation and Biobanking
Marianne K Henderson, Kirstin Goldring, Daniel Simeon-Dubach
No abstract text is available yet for this article.
November 18, 2016: Biopreservation and Biobanking
Susan M Kelly, Luke T Wiehagen, Philip E Schumacher, Rajiv Dhir
This article discusses the evolution of the University of Pittsburgh (UPitt) Health Sciences Tissue Bank (HSTB) operation and how it has successfully positioned itself, manages to sustain its value, and remains viable in today's research landscape. We describe the various components of our biobanking operation, which are valued by our researchers, thus leading to sustainability for our biorepository. Operating within the infrastructure of a large academic university, we have access to the most cutting-edge database resources for collecting, tracking, and annotating thousands of specimens...
November 18, 2016: Biopreservation and Biobanking
Melissa VonDran, Jeffrey A Thomas, Michelle P Freund, Maggie Ritsick, Maureen Orr, Wendy E Kaye, Annette Bakker, Pamela Knight
No abstract text is available yet for this article.
November 15, 2016: Biopreservation and Biobanking
Petr Holub, Morris Swertz, Robert Reihs, David van Enckevort, Heimo Müller, Jan-Eric Litton
No abstract text is available yet for this article.
December 2016: Biopreservation and Biobanking
Alison Parry-Jones, Monique Albert
No abstract text is available yet for this article.
December 2016: Biopreservation and Biobanking
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