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Lower Urinary Tract Symptoms

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https://www.readbyqxmd.com/read/28168811/transobturator-tape-operation-for-the-treatment-of-stress-urinary-incontinence-in-postmenopausal-women-aged-over-65%C3%A2-years
#1
Cenk Yasa, Funda Gungor Ugurlucan, Ozlem Dural, Harika Yumru, Cansu Gunaydin, Onay Yalcin
OBJECTIVE: We compared success rates and complication rates in women aged less then and equal to or more than 65 years who had undergone transobturator tape (TOT) surgery for stress urinary incontinence (SUI). METHODS: This was a retrospective cohort study that included patients who underwent surgery to treat SUI. We separated patients into two groups according to age: younger than 65 years and equal to or older than 65 years. Exclusion criteria were patients with history of incontinence surgery, history of radical pelvic surgery, concomitant pelvic organ prolapse repair, detrusor overactivity, and less than 1 year of postoperative follow-up...
February 6, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28160499/clinical-effects-of-formulated-food-of-peucedanum-japonicum-extract-and-saw-palmetto-extract-in-male-patients-with-lower-urinary-tract-symptoms
#2
Shinji Kageyama, Masanori Beppu, Hiromu Ohnogi, Sayaka Miyazaki, Akihiro Haruno, Yoshihiko Ito, Shizuo Yamada
OBJECTIVES: To evaluate changes over time in subjective symptom scores and urination parameters before and after oral administration of formulated food containing a combination of Peucedanum japonicum (P. japonicum) extract and saw palmetto extract (SPE) in male patients with lower urinary tract symptoms (LUTS). METHODS: This study was conducted in an open label manner on male patients with untreated LUTS. The urination state of patients was evaluated before and after administration of food formulated with P...
February 4, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28150436/efficacy-and-safety-of-gabapentin-in-comparison-to-solifenacin-succinate-in-adult-overactive-bladder-treatment
#3
Michael E Chua, Manuel C See, Ednalyn B Esmeňa, Jaime C Balingit, Marcelino L Morales
OBJECTIVE: To evaluate the efficacy and safety of gabapentin in comparison to solifenacin succinate and placebo for the treatment of adult patients with overactive bladder (OAB). METHOD: A 12-week, randomized, double-blind, double dummy placebo-controlled, clinical trial was conducted between October 2010 and August 2014 at a tertiary medical center. Eligible and consenting patients included were randomized into three treatment groups (placebo, gabapentin and solifenacin)...
February 2, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28009939/comparative-efficacy-and-tolerability-of-antimuscarinic-agents-and-the-selective-%C3%AE-3-adrenoceptor-agonist-mirabegron-for-the-treatment-of-overactive-bladder-which-is-more-preferable-as-an-initial-treatment
#4
Minoru Kobayashi, Akinori Nukui, Takao Kamai
OBJECTIVES: The objective of the present study was to evaluate comparative efficacy and tolerability of antimuscarinics and mirabegron as primary and salvage therapy in patients with overactive bladder (OAB). METHODS: Patients ≥50 years with OAB symptoms were enrolled. Patients were initially treated with antimuscrinics or mirabegron for 8 weeks. When patients were refractory or intolerant to an initial treatment, drugs were switched to the other. The initial and second-line efficacy was assessed at baseline, 4 and 8 weeks after the treatment having the following parameters of the International Prostatic Symptom Score (IPSS), quality of life (QOL) index, Overactive Bladder Symptom Score (OABSS) and post-void residual (PVR) urine volume...
December 23, 2016: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/27990783/radiation-exposure-during-videourodynamics-establishing-risk-factors
#5
Benjamin M Brucker, Lysanne Campeau, Eva Fong, Sidhartha Kalra, Nirit Rosenblum, Victor W Nitti
OBJECTIVES: The use of fluoroscopy during urodynamics can be helpful in the evaluation of patients with lower urinary tract dysfunction. However, fluoroscopy introduces the potential hazards of ionizing radiation, including malignancy. In this study we analyzed the data for radiation exposure during videourodynamic study (VUDS) at our center; we have also tried to establish the factors associated with increased exposure to radiation during VUDS. METHODS: We reviewed all VUDS from August 2010 to May 2011...
December 19, 2016: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/27990752/risk-for-hip-fracture-due-to-alpha-blocker-treatment-in-korean-women-national-health-insurance-database-study
#6
Gi H Seo, Sung R Shim, Hwan W Lee, Jin H Kim, Dong-Il Chun, Hyun J Kim, Hyun Y Lee, Jae H Kim
OBJECTIVE: The aim of this study is to evaluate the risk for hip fracture associated with adverse drug reactions caused by α1-adrenergic (alpha) blockers to treat female voiding dysfunction. METHODS: Information from the Health Insurance Review and Assessment Service database from January 1, 2008 to December 31, 2012 was used. Hip fracture women patients who received a prescription for an alpha blocker due to voiding dysfunction were the cases. A 30-day hazard period after administration of an alpha blocker was set...
December 19, 2016: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/27943566/impact-of-androgen-deprivation-therapy-on-volume-reduction-and-lower-urinary-tract-symptoms-in-patients-with-prostate-cancer
#7
Satoshi Washino, Masaru Hirai, Kimitoshi Saito, Yutaka Kobayashi, Yoshiaki Arai, Tomoaki Miyagawa
OBJECTIVE: To evaluate the impact of androgen deprivation therapy (ADT) on prostate volume, lower urinary tract symptoms (LUTS), and LUTS-related quality of life (QOL) in patients with prostate cancer. METHODS: Patients with prostate cancer (PCa) were treated with goserelin and bicalutamide for 24 weeks. Changes in the total prostate volume (TPV), International Prostate Symptom Score (IPSS), and QOL score for urinary symptoms were assessed every 12 weeks. Of the 42 patients enrolled, 8 patients withdrew and 2 were excluded, so 32 patients were analyzed...
December 12, 2016: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/27911988/long-term-persistence-with-mirabegron-versus-solifenacin-in-women-with-overactive-bladder-prospective-randomized-trial
#8
Manami Kinjo, Yuki Sekiguchi, Yasukuni Yoshimura, Kikuo Nutahara
OBJECTIVES: To compare persistence with medication and the reasons for discontinuation of mirabegron or solifenacin therapy up to12 months in women with overactive bladder (OAB). METHODS: Female OAB patients who presented to women's urology clinics were enrolled in a prospective, randomized, two-arm study. Patients were randomized to receive mirabegron at 25-50 mg (n = 76) or solifenacin at 2.5-5 mg (n = 72). The persistence rate and the reasons for discontinuation were investigated up to 12 months...
December 2, 2016: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/27886448/comment-on-effect-on-sexual-function-of-patients-and-patients-spouses-after-midurethal-sling-procedure-for-stress-urinary-incontinence-a-prospective-single-center-study
#9
LETTER
Antonio Simone Laganà, Valentina Lucia LA Rosa, Agnese Maria Chiara Rapisarda, Salvatore Giovanni Vitale
No abstract text is available yet for this article.
November 25, 2016: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28120450/an-investigation-of-lower-urinary-tract-symptoms-in-women-aged-40-and-over
#10
Neziha Sever, Umran Oskay
OBJECTIVE: The objective of this study was to determine lower urinary tract symptoms (LUTS) and associated risk factors in women aged 40 years and over. METHODS: The study was carried out with a total of 312 women. The data were collected between 1 January 2009 and 30 July 2010. As research instruments, an interview form of 19 questions that questioned personal characteristics and was developed by researchers, and the Bristol Female Lower Urinary Tract Symptoms (BFLUTS) Questionnaire evaluating lower urinary tract symptoms were used...
January 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28120449/correlation-between-advanced-glycation-end-products-lower-urinary-tract-symptoms-and-bladder-dysfunctions-in-patients-with-type-2-diabetes-mellitus
#11
Alessandro Galì, Giuseppe Mucciardi, Salvatore Butticè, Enrica Subba, Carmela D'Amico, Francesco Lembo, Carlo Magno
OBJECTIVES: To explore whether serum and urinary advanced glycation end-products (AGEs) are related to urinary symptoms and bladder dysfunctions in diabetic patients. METHODS: Forty-seven patients with type 2 Diabetes mellitus (T2DM) and lower urinary tract symptoms (LUTS) were enrolled. LUTS evaluation was performed by IPSS (International Prostatic Symptoms Score), QoL (quality of life), OAB (overactive bladder). ICI-SF (International Consultation on Incontinence - short form) quaestionneires; ultrasound examination, evaluation of postvoid residual (PVR), uroflowmetry, cystometry with pressure-flow study (PFS) were performed to detect bladder dysfunctions...
January 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28120448/the-long-term-outcomes-of-the-tension-free-vaginal-tape-procedure-for-treatment-of-female-stress-urinary-incontinence-data-from-minimum-13%C3%A2-years-of-follow-up
#12
Phil Hyun Song, Dae Hyeon Kwon, Young Hwii Ko, Hee Chang Jung
OBJECTIVES: To evaluate the long-term outcomes from the tension-free vaginal tape (TVT) procedure, we investigated the data from a minimum 13-year follow-up and predictive risk factors affecting efficacy for treatment of female stress urinary incontinence (SUI). METHODS: A total of 206 (mean age, 59.2 ± 8.8 years) women who underwent the TVT procedure for SUI were selected and followed up for at least 13 years (mean, 162.4 months; range, 156-174) after TVT procedure...
January 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28120447/effects-of-sildenafil-a-phosphodiesterase-type-5-inhibitor-on-the-primary-single-afferent-activity-of-the-rat-bladder
#13
Naoki Aizawa, Hiroki Ito, Rino Sugiyama, Tetsuya Fujimura, Hiroshi Fukuhara, Haruki Kume, Yukio Homma, Yasuhiko Igawa
OBJECTIVES: We investigated the direct effects of sildenafil, a phosphodiesterase type 5 inhibitor, on the single-unit mechanosensitive afferent activities (SAAs) primarily originated from the bladder in the rat. METHODS: Female Sprague-Dawley rats were anesthetized with urethane. SAAs were recorded from the left L6 dorsal roots and classified by conduction velocity as Aδ- or C-fibers. A catheter was inserted into the bladder dome, and a separate catheter was placed in the carotid artery and external iliac vein for monitoring of blood pressure and sildenafil-administration, respectively...
January 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28120446/phase-iii-study-to-assess-long-term-52-week-safety-and-efficacy-of-mirabegron-a-%C3%AE-3-adrenoceptor-agonist-in-japanese-patients-with-overactive-bladder
#14
Osamu Yamaguchi, Yasushi Ikeda, Sumito Ohkawa
OBJECTIVES: To investigate safety, tolerability and efficacy of long-term (52 weeks) open-label treatment with mirabegron 50 mg, with an optional dose increase to 100 mg, in patients with overactive bladder (OAB). METHODS: Patients received mirabegron 50 mg once daily for 52 weeks. If efficacy was insufficient at week 8, the dose could be increased to 100 mg. Safety was evaluated based on vital signs, adverse events (AEs), laboratory findings, electrocardiogram and post-void residual volume...
January 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28120445/efficacy-and-adherence-of-flexibly-adding-on-a-second-antimuscarinic-agent-for-patients-with-refractory-overactive-bladder
#15
Chung-Cheng Wang, Yuan-Hong Jiang, Hann-Chorng Kuo
OBJECTIVES: To evaluate the efficacy and adverse events (AE) of flexibly adding on oxybutynin ER in patients with overactive bladder (OAB) refractory to monotherapy with the first muscarinic antagonist. METHODS: A total of 129 patients with refractory OAB were enrolled in a prospective, open-label protocol. Inclusion criteria were persistent symptoms or partial response to 3-month behavioral therapy and an optimized dose of one antimuscarinic agent. At baseline, weeks 4, and 12 after the oxybutynin ER (5-15 mg once a day) was flexibly added, we assessed the OAB symptom indexes and Patient Perception of Bladder Condition, uroflowmetry, and post-void residual, along with the therapeutic effect, AE, and tolerability...
January 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28120444/histopathologic-and-urodynamic-effects-of-the-anticholinergic-drugs-oxybutynin-tolterodine-and-trospium-on-the-bladder
#16
Seyfettin Orgen, Hasan Deliktas, Hayrettin Sahin, Abdullah Gedik, Yusuf Nergis
OBJECTIVES: This study aimed to evaluate the effects of intravesical instillation of the anticholinergic drugs oxybutynin, tolterodine, and trospium on bladder capacity and histopathological changes in the bladder mucosa. METHODS: The study included 20 male New Zealand white rabbits that were randomly allocated to four groups of five. In the oxybutynin, tolterodine, and trospium groups, the drugs used were 1 mg/kg of crushed tablet mixed with 5 mL of saline, instilled intravesically once per day for 4 weeks...
January 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28120443/effect-of-voided-volume-on-voiding-patterns-and-reliability-of-uroflowmetry-electromyography-results-in-children-with-lower-urinary-tract-dysfunction
#17
M Murat Dayanc, Yusuf Kibar, H Cem Irkilata, Ahmet A Sancaktutar, Turgay Ebiloglu, Ahmet Gur, Giray Ergin, Bilal F Alp, Faysal Gok
OBJECTIVE: To examine whether voided volume (VV) could change the uroflow patterns and result in children with lower urinary tract dysfunction (LUTD). METHODS: Between January 2009 and May 2010, the children with LUTD were enrolled in this study. Uroflowmetry (UF) combined with electromyography (EMG) was performed two times and was reviewed independently by two urologists. UF-EMG curves were classified as bell, staccato, intermittent, plateau, and tower. Patients' expected bladder capacity (EBC) and VV were recorded...
January 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28120442/evaluation-of-sacrospinous-hysteropexy-vs-uterosacral-suspension-for-the-treatment-of-uterine-prolapse-a-retrospective-assessment
#18
Ahmed Al-Badr, Kauser Perveen, Ghadeer Al-Shaikh
OBJECTIVE: This single-center retrospective study aimed to compare the outcomes of vaginal hysterectomy with utero-sacral suspension (VH/USS) versus sacro-spinous hysteropexy (SSHP) in the management of uterine prolapse at a tertiary care center specializing in Urogynecology. METHODS: The medical records of 50 women with stage 2 or more uterine prolapse treated with VH/USS (n = 26) or SSHP (n = 24) were assessed between January 2006 and December 2012. RESULTS: There were no significant differences between the two groups in terms of body mass index (BMI) and parity P = 0...
January 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28120441/prevalence-of-lower-urinary-tract-symptoms-among-individuals-aged-50%C3%A2-years-and-over-and-its-effect-on-the-quality-of-life-in-a-semi-rural-area-of-western-turkey
#19
Didem Arslantas, Mehmet E Gokler, Alaettin Unsal, Barbaros Başeskioğlu
OBJECTIVES: The number of individuals with lower urinary tract symptoms (LUTS) is increasing as the average age of the men in the community increases. This study aimed to determine the prevalence of LUTS and to assess the quality of life in men aged 50 years and older in Sivrihisar. METHODS: This cross-sectional study was conducted in men aged over 50 years and included 450 subjects. The quality of life was evaluated using the SF-36 Health-Related Quality of Life Scale and the International Prostate Symptom Score (IPSS) to assess the presence and severity of LUTS...
January 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/27860325/safety-and-effectiveness-of-mirabegron-in-patients-with-overactive-bladder-in-a-real-world-clinical-setting-a-japanese-post-marketing-study
#20
Yumiko Nozawa, Daisuke Kato, Hiromi Tabuchi, Kentarou Kuroishi
OBJECTIVES: To provide real-world data on Japanese patients with overactive bladder (OAB) initiating treatment with the β3 -adrenoceptor agonist, mirabegron. This study examined prescribing patterns, adverse drug reaction (ADR) incidence, and treatment effectiveness. METHODS: Full medical histories, including prior/concomitant drug use, were collected before initiating mirabegron treatment. After 12 weeks mirabegron, physicians assessed ADR incidence and treatment effectiveness...
November 17, 2016: Lower Urinary Tract Symptoms
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