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Lower Urinary Tract Symptoms

Sheng-Fu Chen, Cheng-Ling Lee, Hann-Chorng Kuo
OBJECTIVE: Patients with chronic kidney disease (CKD) or end-stage renal disease (ESRD) frequently have lower urinary tract symptoms, such as frequency, urgency, or bladder pain. This study evaluated sensory protein expression in the bladder urothelium of patients with CKD or ESRD. METHODS: Twenty-seven patients with ESRD or CKD and urodynamically proven detrusor underactivity (DU; n = 8) or bladder oversensitivity (n = 19) were enrolled in the study. These patients, and 10 controls, underwent cystoscopic biopsies of the urothelium...
September 9, 2018: Lower Urinary Tract Symptoms
Marco Vella, Alberto Abrate, Angela Costanzo, Francesco D'Amato, Maria L Tarantino, Alchiede Simonato
OBJECTIVE: Acute urinary retention (AUR) is the sudden and painful inability to urinate spontaneously. AUR is one of the most significant complications of benign prostatic enlargement. The management of AUR is based on transurethral catheterization. Subsequent therapy is uncertain, but AUR seems to benefit from the use of alpha-blockers. The aim of this study was to evaluate the variables that could predict which patients would recover spontaneous micturition after trial without catheter...
September 4, 2018: Lower Urinary Tract Symptoms
Yilmaz Unal, Muhammet Fatih Kilinc
OBJECTIVE: The aim of this study was to determine the changes in uroflowmetric values of male patients following elective inguinal hernia repair. METHODS: The study group comprised patients treated with open or laparoscopic inguinal hernia repair. Patients who underwent surgery due to various diseases such as cataract, multinodular goiter, choledocholithiasis, thyroid and breast cancer, hydrocele, or spermatocele were recruited to the control group. Perioperative characteristics, including pain assessed using the visual analog scale (VAS), uroflowmetric values, and post-void residual urine volumes (PVR), were recorded preoperatively and on Postoperative Days (POD) 1 and 30...
August 31, 2018: Lower Urinary Tract Symptoms
Daisuke Kato, Hiromi Tabuchi, Satoshi Uno
OBJECTIVE: The aim of this study was to report the final 3-year results from a surveillance study evaluating the safety, efficacy, and persistence of mirabegron for treating overactive bladder (OAB) symptoms. METHODS: Patients who had started mirabegron for the treatment of urinary urgency, daytime frequency, and urgency urinary incontinence symptoms associated with OAB were followed for 3 years. Adverse drug reactions (ADRs), residual urine volume measurements, OAB symptoms, Overactive Bladder Symptom Scores (OABSS), and treatment discontinuations were evaluated prospectively...
August 5, 2018: Lower Urinary Tract Symptoms
Hsiu-Ying Lin, Ming-Huei Lee, Kun-Min Chang, Huei-Ching Wu
OBJECTIVE: This study compared Taiwanese public health insurance outpatient reimbursements for interstitial cystitis (IC)/bladder pain syndrome (BPS) and rheumatoid arthritis (RA) treatment. METHODS: This observational study used data from the Taiwan Longitudinal Health Insurance Database between 2002 and 2013. Patients with International Classification of Diseases, Ninth Revision, Clinical Modification codes for IC/BPS and RA were selected and matched in a ratio of 1 : 5 based on index year...
August 2, 2018: Lower Urinary Tract Symptoms
Yuka Hayama, Hiroshi Doi, Tae Hasegawa, Yumi Minami, Noriko Ichimura, Mariko Koike, Hiroya Shiomi, Ryoong-Jin Oh, Fumiko Oishi
OBJECTIVE: The aim of the present study was to collect data on the characteristics, degree, and natural course of urinary complications, as well as self-care for such complications, in patients during and after prostate intensity-modulated radiation therapy (IMRT). METHODS: Quality of life data were collected retrospectively for all eligible patients who underwent IMRT. In all eligible patients, urinary symptoms were evaluated using questionnaires and face-to-face interview...
July 16, 2018: Lower Urinary Tract Symptoms
Young Ju Lee, Sung Han Kim, Hwanik Kim, Joong Sub Lee, Songzhe Piao, Seung-June Oh
OBJECTIVE: The aim of this study was to evaluate the value of computed tomography (CT) in determining total prostate volume (TPV), as an alternative to transrectal ultrasonography (TRUS) when TRUS is not available. METHODS: The patient cohort included patients who underwent both CT and TRUS within a 3-month interval from January 2012 to December 2013 at a single institution. In all, 67 non-contrast and 217 contrast-enhanced CT images were reviewed twice by 3 independent observers 2 months after the initial evaluation...
July 16, 2018: Lower Urinary Tract Symptoms
Atsushi Otsuka, Takahisa Suzuki, Ryota Aki, Yuto Matsushita, Keita Tamura, Daisuke Motoyama, Toshiki Ito, Takayuki Sugiyama, Hideaki Miyake
OBJECTIVE: The aim of this study was to investigate the clinical characteristics of nocturia in patients with interstitial cystitis (IC), and the effects of bladder hydrodistention (with fulguration of Hunner lesions) on nocturia. METHODS: The records of 81 patients who were diagnosed with IC were reviewed. Clinical characteristics were evaluated using the Interstitial Cystitis Symptom Index (ICSI), a visual analogue scale (VAS), and bladder diary data. Differences in characteristics between Hunner- and non-Hunner-type IC were compared...
July 16, 2018: Lower Urinary Tract Symptoms
Kristian Vinter Juul, Marie Krarup Schrøder, Birgitte Mahler, Søren Rittig, Jens Peter Nørgaard
OBJECTIVE: This study investigated how desmopressin is prescribed to adults in Denmark. METHODS: All adult users of desmopressin over an 8-year period were identified from the Danish National Prescription Registry. Adult patients with nocturia or nocturnal enuresis (NE) were identified by indication codes for "frequent nocturnal voiding" or "involuntary nocturnal voiding", respectively. Patient demographics, desmopressin formulation and dose, and concomitant medication were investigated...
July 11, 2018: Lower Urinary Tract Symptoms
Lianguang Xie, Yang Chen, Aihua Tan, Yong Gao, Xiaobo Yang, Zengnan Mo, Haiying Zhang
Objective The aim of this study was to explore the association between central obesity and lower urinary tract symptoms (LUTS) among men in southern China, and test the hypothesis that central obesity measured by the waist-to-hip ratio (WHR) is a predictor of the severity of LUTS. Methods In all, 4303 men from the Fangchenggang Area Male Healthy and Examination Survey (FAMHES) were included in this study. LUTS were assessed by the International Prostate Symptom Score (IPSS), whereas central obesity was evaluated by the WHR...
July 3, 2018: Lower Urinary Tract Symptoms
Connie Wang, Philippe E Zimmern, Gary Lemack
OBJECTIVE: This study reports on the long-term results of transurethral endoscopic excision using the Holmium laser (TEEH) for large urethral perforation (UP; defined as involving one-quarter or more of the urethral circumference) from synthetic slings. METHODS: Charts of women treated with TEEH for large UP were reviewed. TEEH was performed using a 365-μm laser fiber passed inside an open-ended ureteral catheter positioned in a holmium laser enucleation of the prostate (HoLEP) sheath to stabilize the laser fiber...
June 28, 2018: Lower Urinary Tract Symptoms
Ho Seok Chung, Sun-Ouck Kim, Dongdeuk Kwon
OBJECTIVE:  The aim of the present study was to verify the usefulness of Point Aa as a substitute marker of the Q-tip angle and urethral mobility before and after midurethral sling operation for the treatment of stress urinary incontinence (SUI) in women. METHODS:  In this study, 118 women presenting with SUI who underwent the tension-free vaginal tape obturator (TVTO) procedure were prospectively examined and followed-up for ≥6 months after operation. Spearman's correlation coefficient was used to assess the degree of correlation between Point Aa of the Pelvic Organ Prolapse Quantification system and Q-tip angles before and after midurethral sling surgery...
June 25, 2018: Lower Urinary Tract Symptoms
Emre Baser, Safak Ozdemirci, Dilek Uysal, Ertugrul Karahanoglu, Akın Sivaslioglu
OBJECTIVE: To evaluate the effects of surgical anatomical correction on lower urinary tract symptoms (LUTS) in patients with a pelvic anterior compartment defect (PACD). METHODS: This prospective study was carried out on 30 women who had stage II-IV PACD. The women were questioned regarding LUTS symptoms such as urgency, urge incontinence, frequency, hesitancy, abnormal emptying, nocturia and dysuria pre and postoperatively. After a 7-month follow up, the comparison of LUTS symptoms with respect to their healing, existence or de novo appearance was performed using the McNemar and Bowner and Wilcoxon signed-rank tests...
September 2018: Lower Urinary Tract Symptoms
Sanae Ninomiya, Kiyoko Naito, Kyoko Nakanishi, Hisayo Okayama
OBJECTIVES: The prevalence of storage symptoms, including stress urinary incontinence (SUI) and overactive bladder (OAB), is high in women worldwide. In Japan, there have been few large-scale epidemiological surveys of lower urinary tract symptoms (LUTS), and the risk factors for these symptoms are unclear. The aim of this study was to explore the prevalence and risk factors of storage symptoms in Japanese women. METHODS: A cross-sectional Internet survey was conducted in Japan...
September 2018: Lower Urinary Tract Symptoms
I-Chun Chen, Ming-Huei Lee, Wei-Chih Chen, Tsung-Ching Hu, Hsiu-Ying Lin
OBJECTIVE: This study investigated the risk factors of ketamine associated-lower urinary tract symptoms (LUTS), such as duration of use, dosage of ketamine, co-occurring substance use of other psychoactive drugs, comorbidities, and depression. METHODS: This study was a cross-sectional survey. LUTS was assessed with the O'Leary symptom and problem index (OSPI) scores. We included the comorbidities of interstitial cystitis/painful bladder syndrome (IC/PBS) as comorbid factors...
September 2018: Lower Urinary Tract Symptoms
Kwang Suk Lee, Kyo Chul Koo, Seung Hwan Lee, Kang Su Cho, Chang-Hee Hong, Byung Ha Chung
OBJECTIVES: We investigated the effect of daily climatic parameters on spontaneous acute urinary retention (sAUR) and evaluated the risk factors for refractory/recurrent AUR. METHODS: A total of 4194 patients older than 40 years were diagnosed with AUR in the emergency department at Gangnam Severance Hospital, Seoul, from January 2007 to May 2016. To evaluate climatic parameters at sAUR onset, we included individuals living in the area around the hospital. We excluded patients with fever, who did not return to the hospital after the AUR episode or with AUR occurring within 2 weeks following admission for surgery or chemotherapy...
September 2018: Lower Urinary Tract Symptoms
Juan P Valdevenito, Arturo García-Mora, Jorge Rodriguez, Andrew Gammie
OBJECTIVES: To compare the initial resting intravesical pressure (pves ) and abdominal pressure (pabd ) in the sitting position with the typical range of values, to assess the correlation between such pressures and patient xipho-pubic distance, body weight, height and body mass index (BMI), and to estimate if xipho-pubic distance can be a guide to interpret initial resting pressures in urodynamic testing. METHODS: Women with lower urinary tract symptomatology referred for urodynamic testing were consecutively enrolled in a prospective study...
September 2018: Lower Urinary Tract Symptoms
Dong Gil Shin, Hyeon Woo Kim, Sung Woo Park, Chang Soo Park, Seong Choi, Tae Hee Oh, Dong Hwan Lee, Chang Yell Lee, Jung Man Kim, Jeong Zoo Lee
OBJECTIVES: To introduce a new surgical mentorship, the "hand-grab navigated technique," to shorten the learning curve for Holmium laser enucleation of the prostate. METHODS: Patients with benign prostatic hyperplasia were managed at six institutions with Holmium laser enucleation of the prostate. An analysis was done in the 200 of these patients (the set of first 20 patients treated with Holmium laser enucleation of the prostate by 10 surgeons) who were sorted into two groups depending on the surgeon's instructional group...
September 2018: Lower Urinary Tract Symptoms
Yuta Yamada, Tetsuya Fujimura, Hiroshi Fukuhara, Toru Sugihara, Tohru Nakagawa, Haruki Kume, Yasuhiko Igawa, Yukio Homma
OBJECTIVE: Our objective was to investigate predictors of early continence outcome after robot-assisted radical prostatectomy (RARP). METHODS: Clinical records were prospectively collected in 272 patients who underwent RARP. Clinical parameters, continence rates, and time to achieve continence were investigated and analyzed. Recovery of continence was defined as achieving complete continence (pad-free). RESULTS: In the univariate analysis, young age (≤67 years) and low pT stage (≤pT2) were significantly associated with continence achieved within 2 weeks after RARP (P = 0...
September 2018: Lower Urinary Tract Symptoms
Chian-Shiung Lin, Tony T-L Wu, Chin-Hong Chang, Juei-Tang Cheng, Yat-Ching Tong
OBJECTIVES: To investigate the effect of high-fat diet (HFD) on bladder M1,3 muscarinic receptor expression and contractile function in the rat. METHODS: Eight-week-old male rats were divided into two groups including one with HFD for 8 weeks (short-term) and the other for 24 weeks (long-term). Each group was compared to age-matched rats fed with normal chow as controls. The body weight, food intake amount and blood biochemistry were monitored. Bladder muscle contractile responses to acetylcholine (0...
September 2018: Lower Urinary Tract Symptoms
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