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Lower Urinary Tract Symptoms

Yuka Hayama, Hiroshi Doi, Tae Hasegawa, Yumi Minami, Noriko Ichimura, Mariko Koike, Hiroya Shiomi, Ryoong-Jin Oh, Fumiko Oishi
OBJECTIVE: The aim of the present study was to collect data on the characteristics, degree, and natural course of urinary complications, as well as self-care for such complications, in patients during and after prostate intensity-modulated radiation therapy (IMRT). METHODS: Quality of life data were collected retrospectively for all eligible patients who underwent IMRT. In all eligible patients, urinary symptoms were evaluated using questionnaires and face-to-face interview...
July 16, 2018: Lower Urinary Tract Symptoms
Young Ju Lee, Sung Han Kim, Hwanik Kim, Joong Sub Lee, Songzhe Piao, Seung-June Oh
OBJECTIVE: The aim of this study was to evaluate the value of computed tomography (CT) in determining total prostate volume (TPV), as an alternative to transrectal ultrasonography (TRUS) when TRUS is not available. METHODS: The patient cohort included patients who underwent both CT and TRUS within a 3-month interval from January 2012 to December 2013 at a single institution. In all, 67 non-contrast and 217 contrast-enhanced CT images were reviewed twice by 3 independent observers 2 months after the initial evaluation...
July 16, 2018: Lower Urinary Tract Symptoms
Atsushi Otsuka, Takahisa Suzuki, Ryota Aki, Yuto Matsushita, Keita Tamura, Daisuke Motoyama, Toshiki Ito, Takayuki Sugiyama, Hideaki Miyake
OBJECTIVE: The aim of this study was to investigate the clinical characteristics of nocturia in patients with interstitial cystitis (IC), and the effects of bladder hydrodistention (with fulguration of Hunner lesions) on nocturia. METHODS: The records of 81 patients who were diagnosed with IC were reviewed. Clinical characteristics were evaluated using the Interstitial Cystitis Symptom Index (ICSI), a visual analogue scale (VAS), and bladder diary data. Differences in characteristics between Hunner- and non-Hunner-type IC were compared...
July 16, 2018: Lower Urinary Tract Symptoms
Kristian Vinter Juul, Marie Krarup Schrøder, Birgitte Mahler, Søren Rittig, Jens Peter Nørgaard
OBJECTIVE: This study investigated how desmopressin is prescribed to adults in Denmark. METHODS: All adult users of desmopressin over an 8-year period were identified from the Danish National Prescription Registry. Adult patients with nocturia or nocturnal enuresis (NE) were identified by indication codes for "frequent nocturnal voiding" or "involuntary nocturnal voiding", respectively. Patient demographics, desmopressin formulation and dose, and concomitant medication were investigated...
July 11, 2018: Lower Urinary Tract Symptoms
Lianguang Xie, Yang Chen, Aihua Tan, Yong Gao, Xiaobo Yang, Zengnan Mo, Haiying Zhang
OBJECTIVE: To explore the association between central obesity and lower urinary tract symptoms (LUTS) among southern men in China, and test the hypothesis that central obesity measured by waist-to-hip ratio (WHR) is the prediction of the severity of LUTS. METHODS: A total of 4,303 men were included in the study from the Fangchenggang Area Male Healthy and Examination Survey (FAMHES). LUTS was assessed by International Prostate Symptom Score (IPSS). The central obesity is evaluated by waist-to-hip ratio...
July 3, 2018: Lower Urinary Tract Symptoms
Connie Wang, Philippe E Zimmern, Gary Lemack
OBJECTIVE: This study reports on the long-term results of transurethral endoscopic excision using the Holmium laser (TEEH) for large urethral perforation (UP; defined as involving one-quarter or more of the urethral circumference) from synthetic slings. METHODS: Charts of women treated with TEEH for large UP were reviewed. TEEH was performed using a 365-μm laser fiber passed inside an open-ended ureteral catheter positioned in a holmium laser enucleation of the prostate (HoLEP) sheath to stabilize the laser fiber...
June 28, 2018: Lower Urinary Tract Symptoms
Ho Seok Chung, Sun-Ouck Kim, Dongdeuk Kwon
OBJECTIVE:  The aim of the present study was to verify the usefulness of Point Aa as a substitute marker of the Q-tip angle and urethral mobility before and after midurethral sling operation for the treatment of stress urinary incontinence (SUI) in women. METHODS:  In this study, 118 women presenting with SUI who underwent the tension-free vaginal tape obturator (TVTO) procedure were prospectively examined and followed-up for ≥6 months after operation. Spearman's correlation coefficient was used to assess the degree of correlation between Point Aa of the Pelvic Organ Prolapse Quantification system and Q-tip angles before and after midurethral sling surgery...
June 25, 2018: Lower Urinary Tract Symptoms
Samer Shamout, Yu Qing Huang, Hani Kabbara, Jacques Corcos, Lysanne Campeau
OBJECTIVE: The Argus perineal sling is a minimally invasive surgical option to treat post-prostatectomy stress urinary incontinence (PPSUI). This study retrospectively evaluated the short-term clinical outcomes with the Argus sling for PPSUI management and determined the effects of potential preoperative parameters on intraoperative retrograde leak point pressure (RLPP). METHODS: In this retrospective review of 16 men with various degrees of stress incontinence after prostatic surgery who underwent Argus sling, PPSUI was evaluated by pad usage, urodynamics, 24-hour pad weight, and validated questionnaires...
June 4, 2018: Lower Urinary Tract Symptoms
Misato Takayama, So Omori, Kazuhiro Iwasaki, Ei Shiomi, Ryo Takata, Jun Sugimura, Takaya Abe, Wataru Obara
OBJECTIVE: The aim of the present study was to examine factors of nocturnal polyuria and blood pressure variability in male patients with lower urinary tract symptoms (LUTS) who were treated. METHODS: Two hundred and forty-two male patients with LUTS who were treated recorded frequency volume charts. We investigated their urinary condition and characteristics, medical history, and medications. Thirty-four of these patients underwent ambulatory blood pressure monitoring (ABPM) for 24 hours to evaluate blood pressure variability...
May 29, 2018: Lower Urinary Tract Symptoms
Hueih Ling Ong, Yuan-Hong Jiang, Hann-Chorng Kuo
OBJECTIVE: The aim of the present study was to investigate the effectiveness of repeat retropubic suburethral sling for recurrent stress urinary incontinence (SUI) in women. METHODS: A retrospective review was performed of 35 women with SUI who underwent repeat retropubic suburethral sling procedures between May 1994 and November 2014. Treatment outcome was assessed directly or by telephone interview. Sling position and urethral incompetence during straining and coughing after the procedure were evaluated...
April 27, 2018: Lower Urinary Tract Symptoms
Cheng-Ling Lee, Hann-Chorng Kuo
OBJECTIVE: We examined the efficacy and safety of mirabegron in elderly patients with urodynamic detrusor hyperactivity with impaired contractility (DHIC). METHODS: Patients diagnosed with DHIC received daily dose of mirabegron (25mg). Subjective symptom scores, uroflowmetry data, and adverse events (AEs) were recorded for all patients at baseline and after 1, 3, and 6 months treatment. Comparisons were made for each patient individually and between patients with detrusor overactivity (DO)...
April 26, 2018: Lower Urinary Tract Symptoms
Naoya Masumori, Yuya Funato, Yasunobu Yamaguchi, Kunio Itoh
OBJECTIVES: In recent years, some patients have been unresponsive to anticholinergics used in the treatment of pollakisuria/urinary incontinence. It has been suggested that propiverine hydrochloride, which has not only anticholinergic activity, but also calcium antagonistic activity, may be useful in poor responders to other anticholinergics. In this study, a specific drug use-results survey was conducted in poor responders to other anticholinergics to evaluate the usefulness of propiverine hydrochloride...
May 2018: Lower Urinary Tract Symptoms
Lingfeng Liu, Kang Zhao, Fan Chen, Jian Wu, Zhaofeng Yang, Ming Chen, Linbo Mao, Jiurong Han
OBJECTIVE: To develop a portable dynamic bladder pressure monitoring device for facilitating the monitoring of bladder detrusor pressure in patients with neurogenic bladder (NB) caused by spinal cord injury and further compared the effect with traditional urodynamics devices. METHODS: Portable dynamic bladder pressure monitoring device was implemented by software and hardware. The hardware was mainly composed of seven parts, such as micro liquid pressure sensor, electric bridge amplifying circuit, clock module, SD card storage circuit, liquid crystal display circuit, touch circuit, controller circuit and so on...
May 2018: Lower Urinary Tract Symptoms
Ji S Shim, Jae H Kim, Yong S Yoon, Hoon Choi, Jae Y Park, Jae H Bae
OBJECTIVES: To investigate the correlation of serum total testosterone levels with International Prostate Symptom Score and prostate volume in aging men. METHODS: A cross-sectional study was conducted in 50 men who had participated in a medical examination. Prostate specific antigen levels, International Prostate Symptom Score, total/transitional prostate volume, body mass index, maximal flow rate, and serum total testosterone levels were evaluated. The correlation between serum total testosterone levels and additional parameters was statistically analyzed...
May 2018: Lower Urinary Tract Symptoms
Sezgin Okçelik, Hasan Soydan, Ferhat Ateş, Ömer Yilmaz, Ercan Malkoç, Temuçin Şenkul, Kenan Karademir
OBJECTIVES: Our aim was to examine correlation between Post-void residual urine (PVR) after uroflowmetry and random PVR. METHODS: Male patients reporting to the Urology outpatient clinic with LUTS were selected. Patients' age, prostate volume, bladder capacity, voided volume, maximum flow rate, average flow rate, random PVR and PVR after uroflowmetry were recorded. We evaluated the correlations between these parameters. Also we assessed if there was a difference between random PVR and PVR after uroflowmetry...
May 2018: Lower Urinary Tract Symptoms
Hidekazu Matsuya, Noritoshi Sekido, Jun Kida, Hiroko Mashimo, Daisuke Wakamatsu, Hiroki Okada
OBJECTIVES: The objective was to develop an underactive bladder (UAB) model in primates and to evaluate the potential of prostanoid EP2 and EP3 receptor dual agonist ONO-8055 to become a therapeutic agent for UAB. METHODS: A surgical procedure resembling radical hysterectomy was performed on female cynomolgus monkeys. Subsequently, in vitro muscle strip studies were performed using bladder muscle strips from normal monkeys and monkeys that underwent surgery. In addition, uroflowmetric data were obtained at specified days after the surgery...
May 2018: Lower Urinary Tract Symptoms
Abbas Ali Pourmomeny, Behnaz Ghanei, Farshid Alizadeh
OBJECTIVES: Assessment instruments are essential for research, allowing diagnosis and evaluating treatment outcomes in subjects with lower urinary tract disorders of both genders. The purpose of this study was to translate the Male Lower Urinary Tract Symptoms (MLUTS) Questionnaire and determine its psychometric properties in Persian subjects. METHODS: After getting permission from the International Consultation on Incontinence Modular Questionnaire (ICIQ) web site, the forward and backward translation of the MLUTS questionnaire were carried out by researcher team...
May 2018: Lower Urinary Tract Symptoms
I-Hung Chen, Juei-Tang Cheng, Yat-Ching Tong
OBJECTIVES: To investigate the effect of metabolic syndrome on the bladder cannabinoid receptors 1 and 2 (CB1/CB2) expression and function in the fructose-fed rats (FR). METHODS: Adult male Sprague-Dawley rats were divided into two groups: (i) Control rats fed with normal chow; and (ii) Rats fed with high-fructose diet (FR) for 9 weeks. The body weight, blood pressure, plasma sugar, insulin, triglyceride and cholesterol were measured. Bladder muscle strips were prepared in organ bath and pre-contracted with 1 µM/L acetylcholine (ACh) or 50 mM/L KCl...
May 2018: Lower Urinary Tract Symptoms
Ashwin Mallya, Ramaiah Keshavamurthy, Vilvapathy S Karthikeyan, Sumit Kumar, Mahadevappa Nagabhushana, Ananth J Kamath
OBJECTIVE: The American Urology Association symptom index (AUASI) is the most accepted tool to assess lower urinary tract symptoms (LUTS). UWIN (urgency, weak stream, incomplete void, nocturia) score is a simplified questionnaire with fewer and more distinctive options omitting three questions from AUASI. We sought to identify if UWIN is equally efficient in capturing LUTS and could replace the gold-standard AUASI. METHODS: Consecutive consenting male patients with benign prostatic hyperplasia (BPH)-LUTS were randomized to receive either UWIN/AUASI questionnaire first followed by the other...
May 2018: Lower Urinary Tract Symptoms
Jai Seth, Sophie Rintoul-Hoad, Arun Sahai
The first reported application of Botulinum toxin-A (BTX-A) into the urethral sphincter predates the first documented use in the bladder. The aim of this review is to describe the clinical indications of BTX-A injection into the urethral sphincter and its clinical efficacy. This review of the literature includes the larger more significant published studies that have reported on this use of BTX-A. Case reports and articles not published in English were excluded. There have been many published clinical studies describing the use of BTX-A in the urethral sphincter, four of which are randomized placebo controlled trials...
May 2018: Lower Urinary Tract Symptoms
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