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Lower Urinary Tract Symptoms

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https://www.readbyqxmd.com/read/28762672/safety-efficacy-and-persistence-of-long-term-mirabegron-treatment-for-overactive-bladder-in-the-daily-clinical-setting-interim-1-year-report-from-a-japanese-post-marketing-surveillance-study
#1
Daisuke Kato, Hiromi Tabuchi, Satoshi Uno
OBJECTIVES: To report interim 1-year results from a 3-year surveillance study evaluating safety, efficacy, and persistence of long-term mirabegron for overactive bladder (OAB). METHODS: Patients starting treatment with mirabegron for urinary urgency, daytime frequency, and urgency incontinence associated with OAB were registered and followed up for 3 years. Data were collected on adverse drug reactions (ADR), changes in OAB symptoms, changes in Overactive Bladder Symptom Score (OABSS), and treatment discontinuations...
August 1, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28762663/impact-of-monopolar-turp-bipolar-turp-and-photoselective-vaporization-of-prostate-for-enlarged-prostate-on-erectile-function
#2
Pawan Vasudeva, Niraj Kumar, Anup Kumar, Gaurav Kumar, Mikir Patel, Pankaj Gupta
OBJECTIVES: To compare monopolar transurethral resection of the prostate (TURP), bipolar TURP and photoselective vaporization of the prostate (PVP) by 120-W GreenLight laser with regard to the impact on International Index of Erectile Function (IIEF)-5 score in patients presenting with lower urinary tract symptoms (LUTS) secondary to prostate >80 mL. METHODS: Between April 2012 and March 2015, 110 patients who satisfied eligibility criteria were divided into three groups according to surgical modality adopted to treat benign prostatic enlargement...
August 1, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28762631/prevalence-and-risk-factors-of-urinary-incontinence-and-overactive-bladder-in-japanese-women
#3
Sanae Ninomiya, Kiyoko Naito, Kyoko Nakanishi, Hisayo Okayama
OBJECTIVES: The prevalence of storage symptoms, including stress urinary incontinence (SUI) and overactive bladder (OAB), is high in women worldwide. In Japan, there have been few large-scale epidemiological surveys of lower urinary tract symptoms (LUTS), and the risk factors for these symptoms are unclear. The aim of this study was to explore the prevalence and risk factors of storage symptoms in Japanese women. METHODS: A cross-sectional Internet survey was conducted in Japan...
August 1, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28707385/risk-factors-of-lower-urinary-tract-syndrome-among-ketamine-users
#4
I-Chun Chen, Ming-Huei Lee, Wei-Chih Chen, Tsung-Ching Hu, Hsiu-Ying Lin
OBJECTIVE: This study investigated the risk factors of ketamine associated-lower urinary tract symptoms (LUTS), such as duration of use, dosage of ketamine, co-occurring substance use of other psychoactive drugs, comorbidities, and depression. METHODS: This study was a cross-sectional survey. LUTS was assessed with the O'Leary symptom and problem index (OSPI) scores. We included the comorbidities of interstitial cystitis/painful bladder syndrome (IC/PBS) as comorbid factors...
July 13, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28707361/effect-of-climatic-parameters-on-acute-urinary-retention-incidence
#5
Kwang Suk Lee, Kyo Chul Koo, Seung Hwan Lee, Kang Su Cho, Chang-Hee Hong, Byung Ha Chung
OBJECTIVES: We investigated the effect of daily climatic parameters on spontaneous acute urinary retention (sAUR) and evaluated the risk factors for refractory/recurrent AUR. METHODS: A total of 4194 patients older than 40 years were diagnosed with AUR in the emergency department at Gangnam Severance Hospital, Seoul, from January 2007 to May 2016. To evaluate climatic parameters at sAUR onset, we included individuals living in the area around the hospital. We excluded patients with fever, who did not return to the hospital after the AUR episode or with AUR occurring within 2 weeks following admission for surgery or chemotherapy...
July 13, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28707318/correlation-of-xiphopubic-distance-body-weight-height-and-body-mass-index-with-intravesical-and-abdominal-initial-resting-pressures-in-urodynamic-testing-in-the-sitting-position
#6
Juan P Valdevenito, Arturo García-Mora, Jorge Rodriguez, Andrew Gammie
OBJECTIVES: To compare the initial resting intravesical pressure (pves ) and abdominal pressure (pabd ) in the sitting position with the typical range of values, to assess the correlation between such pressures and patient xipho-pubic distance, body weight, height and body mass index (BMI), and to estimate if xipho-pubic distance can be a guide to interpret initial resting pressures in urodynamic testing. METHODS: Women with lower urinary tract symptomatology referred for urodynamic testing were consecutively enrolled in a prospective study...
July 13, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28699307/new-surgical-instruction-method-for-homium-laser-enucleation-of-the-prostate-hand-grab-navigated-technique-to-shorten-the-learning-curve-the-results-of-multicenter-analysis
#7
Dong Gil Shin, Hyeon Woo Kim, Sung Woo Park, Chang Soo Park, Seong Choi, Tae Hee Oh, Dong Hwan Lee, Chang Yell Lee, Jung Man Kim, Jeong Zoo Lee
OBJECTIVES: To introduce a new surgical mentorship, the "hand-grab navigated technique," to shorten the learning curve for Holmium laser enucleation of the prostate. METHODS: Patients with benign prostatic hyperplasia were managed at six institutions with Holmium laser enucleation of the prostate. An analysis was done in the 200 of these patients (the set of first 20 patients treated with Holmium laser enucleation of the prostate by 10 surgeons) who were sorted into two groups depending on the surgeon's instructional group...
July 11, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28699263/predictors-of-early-continence-after-robot-assisted-radical-prostatectomy
#8
Yuta Yamada, Tetsuya Fujimura, Hiroshi Fukuhara, Toru Sugihara, Tohru Nakagawa, Haruki Kume, Yasuhiko Igawa, Yukio Homma
OBJECTIVE: Our objective was to investigate predictors of early continence outcome after robot-assisted radical prostatectomy (RARP). METHODS: Clinical records were prospectively collected in 272 patients who underwent RARP. Clinical parameters, continence rates, and time to achieve continence were investigated and analyzed. Recovery of continence was defined as achieving complete continence (pad-free). RESULTS: In the univariate analysis, young age (≤67 years) and low pT stage (≤pT2) were significantly associated with continence achieved within 2 weeks after RARP (P = 0...
July 11, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28681521/changes-of-bladder-m1-3-muscarinic-receptor-expression-in-rats-fed-with-short-term-long-term-high-fat-diets
#9
Chian-Shiung Lin, Tony T-L Wu, Chin-Hong Chang, Juei-Tang Cheng, Yat-Ching Tong
OBJECTIVES: To investigate the effect of high-fat diet (HFD) on bladder M1,3 muscarinic receptor expression and contractile function in the rat. METHODS: Eight-week-old male rats were divided into two groups including one with HFD for 8 weeks (short-term) and the other for 24 weeks (long-term). Each group was compared to age-matched rats fed with normal chow as controls. The body weight, food intake amount and blood biochemistry were monitored. Bladder muscle contractile responses to acetylcholine (0...
July 5, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28675636/prevalence-of-urinary-incontinence-during-pregnancy-and-associated-risk-factors
#10
Ayten Dinç
OBJECTIVE: To investigate the prevalence of urinary incontinence during pregnancy and associated risk factors. METHODS: The study is a cross-sectional and descriptive study. A questionnaire was conducted with a total of 750 pregnant women about their urinary incontinence complaints between April and December 2013. RESULTS: The prevalence of urinary incontinence during pregnancy was 300 in 750 (40%). Stress urinary incontinence was the most common type of incontinence during pregnancy...
July 4, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28675645/adult-onset-nocturnal-enuresis-identifying-causes-cofactors-and-impact-on-quality-of-life
#11
Dominic Lee, Benjamin E Dillon, Gary E Lemack
OBJECTIVES: The objectives of the present study were: (i) Evaluate common co-pathologies associated with, and potentially contributing to adult onset Nocturnal enuresis (NE) in a tertiary referral population; and (ii) quantify its impact on QoL with validated questionnaires. METHODS: Following Institutional Review Board approval, patients with adult onset NE were reviewed with history, physical examination, urodynamic studies, questionnaires: Overactive bladder questionnaire short-form (OAB-qSF), Urogenital Distress Inventory (UDI-6), AUA symptom score (AUA-SS) and Patient Global Impression scale (PGIS)...
July 3, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28675633/increased-urine-production-due-to-leg-fluid-displacement-reduces-hours-of-undisturbed-sleep
#12
Keisuke Kiba, Akihide Hirayama, Motokiyo Yoshikawa, Yutaka Yamamoto, Kazumasa Torimoto, Nobutaka Shimizu, Nobumichi Tanaka, Kiyohide Fujimoto, Hirotsugu Uemura
OBJECTIVE: To investigate whether or not the leg fluid displacement observed when moving from the standing to recumbent position at bedtime reduces the hours of undisturbed sleep (HUS). METHODS: Men aged 50 years or older who were hospitalized for urological diseases were investigated. Body water evaluation was performed three times with a bioelectric impedance method: (i) 17:00, (ii) 30 min after (short-term), and (iii) waking up (long-term). A frequency volume chart was used to evaluate the status of nocturnal urine production, and the factors affecting HUS were investigated...
July 3, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28657139/complications-following-the-insertion-of-two-synthetic-mid-urethral-slings-and-subsequent-removal
#13
Dominic Lee, Chasta Bacsu, Benjamin Dillon, Philippe E Zimmern
OBJECTIVE: To determine outcomes after removal of two synthetic mid-urethral slings (MUS) at a tertiary care center. METHODS: Following IRB approval, a retrospective chart review of non-neurogenic, symptomatic women requiring re-operation after ≥2 MUS was performed. Data reviewed by a third party included: demographics, prior anti-incontinence surgery, complications, pelvic/urinary symptoms, subsequent investigations, surgical repair and outcomes (including UDI-6/IIQ-7 questionnaires) at a minimum 6 months follow-up...
June 28, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28643427/correlation-between-residual-volume-of-male-patients-after-uroflowmetry-and-random-residual-volume
#14
Sezgin Okçelik, Hasan Soydan, Ferhat Ateş, Ömer Yilmaz, Ercan Malkoç, Temuçin Şenkul, Kenan Karademir
OBJECTIVES: Our aim was to examine correlation between Post-void residual urine (PVR) after uroflowmetry and random PVR. METHODS: Male patients reporting to the Urology outpatient clinic with LUTS were selected. Patients' age, prostate volume, bladder capacity, voided volume, maximum flow rate, average flow rate, random PVR and PVR after uroflowmetry were recorded. We evaluated the correlations between these parameters. Also we assessed if there was a difference between random PVR and PVR after uroflowmetry...
June 23, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28627109/high-power-magnetotherapy-a-new-weapon-in-urinary-incontinence
#15
Maria Vadalà, Beniamino Palmieri, Andrea Malagoli, Carmen Laurino
OBJECTIVE: Urinary incontinence (UI) is one of the most common urinary system diseases that mostly affects women but also men. We evaluated the therapeutic efficacy of functional magnetic stimulation (FMS) as potential UI treatment with improvements in the pelvic floor musculature, urodynamic tests and quality of life. METHODS: A total of 20 UI patients (10 females and 10 men, mean age 64, 14 years), including 10 with stress UI, four with urgency UI and six with mixed UI, were treated with FMS (20 min/session) twice a week for 3 weeks...
June 18, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28573832/effect-of-preoperative-low-maximal-flow-rate-on-postoperative-voiding-trials-after-the-midurethral-sling-procedure-in-women-with-stress-urinary-incontinence
#16
Ji Y Chae, Jae H Bae, Jeong G Lee, Hong S Park, Du G Moon, Mi M Oh
OBJECTIVES: To evaluate the effects of preoperative low maximal flow rate (Qmax) on voiding trials after the midurethral sling (MUS) procedure in women with stress urinary incontinence (SUI). METHODS: One hundred and sixty-eight women who underwent MUS procedure were enrolled. Preoperative free uroflowmetry was performed and patients were divided by Qmax. Low Qmax was defined as a Qmax under 15 mL/sec with voided volume at least 150 mL. Surgical results, failure of voiding trial, and postoperative uroflowmetry parameters were compared between the groups...
June 2, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28573791/early-experiences-of-contact-laser-vaporization-of-the-prostate-using-the-980%C3%A2-nm-high-power-diode-laser-for-benign-prostatic-hyperplasia
#17
Hideyo Miyazaki, Yoshikazu Hirano, Shinobu Kato, Naomasa Ioritani, Takaharu Ichikawa, Hitoshi Takamoto, Yukio Homma
OBJECTIVES: We report early experiences of contact laser vaporization of the prostate for symptomatic benign prostatic hyperplasia (BPH). METHODS: A total of 80 patients recruited at four institutions in Japan from April 2013 through September 2014 underwent contact laser vaporization of the prostate using 980 nm high power diode laser with an end-firing fiber in the contact mode. Patients were followed prospectively at 1 day, 2, 4, 8, 12, and 24 weeks, postoperatively per protocol, and at 1 and 2 years post-protocol...
June 2, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28560762/low-dose-desmopressin-and-tolterodine-combination-therapy-for-treating-nocturia-in-women-with-overactive-bladder-a-double-blind-randomized-controlled-study
#18
Eric S Rovner, Kyle Raymond, Eugene Andruczyk, Kristian V Juul
OBJECTIVE: Evaluation of safety and efficacy of desmopressin/tolterodine combination therapy in women. METHODS: This double-blind, randomized, proof-of-concept study enrolled 106 patients (≥18 years), with overactive bladder (OAB) and nocturia, with ≥2 nocturnal voids, receiving a 3-month once-daily combination (desmopressin 25 µg, orally-disintegrating tablets [ODT]/tolterodine 4 mg [Detrol® LA]; n = 49) or monotherapy (tolterodine 4 mg/placebo ODT; n = 57)...
May 31, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28394500/naftopidil-improves-symptoms-in-a-rat-model-of-tranilast-induced-interstitial-cystitis
#19
Kimio Sugaya, Saori Nishijima, Katsumi Kadekawa, Katsuhiro Ashitomi, Tomoyuki Ueda, Hideyuki Yamamoto
OBJECTIVE: The effect of naftopidil on symptoms of tranilast-induced interstitial cystitis (IC) was examined in rats. METHODS: Thirty-two female rats were divided into four groups (control, naftopidil, tranilast, and combination groups). Rats in the control group were fed a standard diet, while rats in the naftopidil, tranilast, and combination groups were fed diets containing naftopidil, tranilast, or naftopidil + tranilast, respectively. After 4 weeks of treatment, locomotor activity was measured and continuous cystometry was performed...
May 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28394499/antioxidant-agent-quercetin-prevents-impairment-of-bladder-tissue-contractility-and-apoptosis-in-a-rat-model-of-ischemia-reperfusion-injury
#20
Ilker Tinay, Tarik E Sener, Ozge Cevik, Selin Cadirci, Hale Toklu, Sule Cetinel, Göksel Sener, Tufan Tarcan
OBJECTIVES: To examine the possible protective effect of quercetin (QT), which is well known for its antioxidant and protective effects in circumstances of oxidative stress, on urinary bladder tissue in a rat model of ischemia/reperfusion (I/R) injury, which is a known factor for the development of lower urinary tract dysfunction partly mediated by the generation of free radicals causing oxidative damage. METHODS: Thirty male Sprague-Dawley rats were subjected to I/R injury through clamping the abdominal aorta for 30 min and then allowing reperfusion for the next 60 min...
May 2017: Lower Urinary Tract Symptoms
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