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Journal of Contemporary Brachytherapy

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https://www.readbyqxmd.com/read/29619061/the-effect-of-tandem-ovoid-titanium-applicator-on-points-a-b-bladder-and-rectum-doses-in-gynecological-brachytherapy-using-192-ir
#1
Mohammad Hosein Sadeghi, Sedigheh Sina, Amir Mehdizadeh, Reza Faghihi, Vahed Moharramzadeh, Ali Soleimani Meigooni
Purpose: The dosimetry procedure by simple superposition accounts only for the self-shielding of the source and does not take into account the attenuation of photons by the applicators. The purpose of this investigation is an estimation of the effects of the tandem and ovoid applicator on dose distribution inside the phantom by MCNP5 Monte Carlo simulations. Material and methods: In this study, the superposition method is used for obtaining the dose distribution in the phantom without using the applicator for a typical gynecological brachytherapy (superposition-1)...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619060/reduction-of-applicator-displacement-in-mr-ct-guided-cervical-cancer-hdr-brachytherapy-by-the-use-of-patient-hover-transport-system
#2
Megan Andrew, Yusung Kim, Timothy Ginader, Brian J Smith, Wenqing Sun, Dongxu Wang
Purpose: To quantify the reduction of relative displacement between the implanted intracavitary applicator and the patient bony anatomy, due to the use of a hover transport system during the patient transports between the imaging table and the treatment table. Material and methods: The displacement of the applicator inside the patient was measured by comparing the distance between the tip of the tandem and the pubic bone on X-ray radiography images taken before and after moving a patient to magnetic resonance/computed tomography imaging...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619059/a-comparative-assessment-of-inhomogeneity-and-finite-patient-dimension-effects-in-60-co-and-192-ir-high-dose-rate-brachytherapy
#3
Irina Fotina, Kyveli Zourari, Vasileios Lahanas, Evaggelos Pantelis, Panagiotis Papagiannis
Purpose: To perform a comparative study of heterogeneities and finite patient dimension effects in60 Co and192 Ir high-dose-rate (HDR) brachytherapy. Material and methods: Clinically equivalent plans were prepared for 19 cases (8 breast, 5 esophagus, 6 gynecologic) using the Ir2.A85-2 and the Co0.A86 HDR sources, with a TG-43 based treatment planning system (TPS). Phase space files were obtained for the two source designs using MCNP6, and validated through comparison to a single source dosimetry results in the literature...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619058/long-term-outcome-of-high-dose-rate-brachytherapy-and-perioperative-brachytherapy-in-early-mobile-tongue-cancer
#4
Mahadev Potharaju, Hemanth Raj E, Manavalan Muthukumaran, Murali Venkataraman, Bhargavi Ilangovan, Selvan Kuppusamy
Purpose: To evaluate long-term outcome of high-dose-rate brachytherapy and perioperative brachytherapy in early mobile tongue cancer. Material and methods: Seventy-three patients with clinically staged T1/T2 N0 M0 of mobile tongue cancer were studied retrospectively. Between January 2000 and September 2010, 47 patients underwent high-dose-rate brachytherapy (HDR-BT) alone and 26 patients underwent perioperative brachytherapy (PB). Endpoints were overall survival, disease-free survival, loco-regional control, and late side effects...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619057/accelerated-partial-breast-irradiation-in-a-single-18-gy-fraction-with-high-dose-rate-brachytherapy-preliminary-results
#5
Javier Anchuelo Latorre, Piedad Galdós, Lucía Alonso Buznego, Ana García Blanco, Juan Cardenal, María Ferri, Iván Díaz de Cerio, Elisabet Arrojo, Nicolás Sierrasesúmaga, Mónica González Noriega, Ana De Juan Ferré, Rosa Fabregat, Samuel Ruíz, Pedro J Prada
Purpose: To evaluate the feasibility of acute and chronic toxicity in patients suitable for accelerated partial breast irradiation (APBI) in a single 18 Gy fraction with multicatheter high-dose-rate (HDR) brachytherapy, as well as cosmetic and oncological outcomes. Material and methods: Between September 2014 and March 2016, twenty consecutive patients with low-risk invasive and ductal carcinoma in situ were treated with interstitial multicatheter HDR brachytherapy in a single 18 Gy fraction...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619056/should-molecular-subtype-be-recommended-as-one-of-the-selection-criteria-for-accelerated-partial-breast-irradiation-preliminary-results-from-an-asian-cohort
#6
Tabassum Wadasadawala, Monidipa Mondal, Siji Nojin Paul, Vani Parmar, Nita Nair, Tanuja Shet, Sangeeta Desai, Sudeep Gupta, Rajiv Sarin
Purpose: The purpose of this study was to report clinical outcomes in patients treated with accelerated partial breast irradiation (APBI), stratified as per molecular subtype and American Society for Therapeutic Radiology and Oncology/Groupe Européen de Curiethérapie and European Society for Radiotherapy & Oncology (ASTRO/GEC-ESTRO) patient selection criteria in order to determine whether molecular subtype should be recommended as one of the selection criteria for APBI. Material and methods: 157 early-stage breast cancers patients, treated with APBI using multi-catheter interstitial brachytherapy with ≥ 6 months follow-up were included...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619055/late-g2-vagina-toxicity-in-post-operative-endometrial-carcinoma-is-associated-with-a-68-gy-dose-equivalent-to-2-gy-per-fraction-%C3%AE-%C3%AE-3gy-at-2-cm-3-of-vagina
#7
María Del Valle Aguilera, Ángeles Rovirosa, Carlos Ascaso, Antonio Herreros, Joan Sánchez, Julia Garcia-Migue, Stephanía Cortes, Eduardo Agusti, Cristina Camacho, Yaowen Zhang, Yan Li, Sebastià Sabater, Aureli Torne, Meritxell Arenas
Purpose: To evaluate if the dose equivalent to 2 Gy per fraction (EQD2)(α/β=3Gy) at 0.1 cm3 , 1 cm3 , and 2 cm3 of vagina in vaginal-cuff-brachytherapy (VBT) (high-dose-rate [HDR] 192 Ir-source) ± external-beam-irradiation (EBRT) is associated with toxicity in post-operative endometrial carcinoma (P-EC). Material and methods: From June 2014 till November 2015, 67 consecutive P-EC patients underwent VBT ± EBRT; 44 patients received EBRT (median, 45 Gy; range, 44-50...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619054/clinical-analysis-of-speculum-based-vaginal-packing-for-high-dose-rate-intracavitary-tandem-and-ovoid-brachytherapy-in-cervical-cancer
#8
Shivani Sud, Toni Roth, Ellen Jones
Purpose: Intra-vaginal packing is used to fix the applicator and displace organs at risk (OAR) during high-dose-rate intracavitary tandem and ovoid brachytherapy (HDR-ICB). We retain the speculum from applicator placement as a dual-function bladder and rectum retractor during treatment. Our objective is to review salient techniques for OAR displacement, share our packing technique, and determine the reduction in dose to OAR and inter-fraction variability of dose to OAR, associated with speculum-based vaginal packing (SBVP) in comparison to conventional gauze packing during HDR-ICB...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619053/dosimetric-analysis-of-the-effects-of-the-bladder-volume-on-organs-at-risk-oar-in-high-dose-rate-intracavitary-brachytherapy-in-carcinoma-cervix-an-institutional-study
#9
Ashutosh Das Sharma, Jyoti Poddar, U Suryanarayan K, Sonal Patel Shah, Ankita Parikh, Vimesh Mehta, Med Phys, Tarun Kumar, Med Phys
Purpose: The purpose of this study was to establish a dosimetric correlation between the bladder volume and its effects on the dose received by the organs at risk (OARs) (urinary bladder, rectum, and sigmoid) during computed tomography (CT)-guided high-dose-rate (HDR) brachytherapy in carcinoma cervix, and to determine an optimum bladder volume to limit the dose to OARs. Material and methods: Seventy-five intracavitary applications in patients of carcinoma cervix (stage IIB, IIIA, IIIB, IVA) treated with external beam radiotherapy with concurrent chemotherapy followed by CT-based HDR intracavitary brachytherapy (tandem and ovoid type) at our institute between July 2014 to January 2016 were studied...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619052/impact-of-brachytherapy-technique-2d-versus-3d-on-outcome-following-radiotherapy-of-cervical-cancer
#10
Kris Derks, Jacco L G Steenhuijsen, Hetty A van den Berg, Saskia Houterman, Jeltsje Cnossen, Paul van Haaren, Katrien De Jaeger
Purpose: The purpose of this study was to analyze the effect of 2D conventional brachytherapy (CBT) compared to 3D MRI-guided brachytherapy (IGBT) with and without the use of interstitial needles on local control, overall survival, and toxicity in patients treated for cervical cancer with radiation or chemoradiation. Material and methods: A retrospective analysis was performed of biopsy-proven FIGO IB-IVA cervical cancer patients, treated with primary radiation or chemoradiation, followed by brachytherapy (BT) between January 1997 and July 2016...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619051/a-cold-spot-compensation-technique-using-a-combination-of-trans-rectal-ultrasonography-and-intraoperative-computed-tomography-for-interstitial-permanent-prostate-brachytherapy-a-single-arm-prospective-trial
#11
Hiromichi Ishiyama, Hideyasu Tsumura, Shogo Kawakami, Takefumi Satoh, Akane Sekiguchi, Ken-Ichi Tabata, Masatsugu Iwamura, Kazushige Hayakawa
Purpose: To evaluate the efficacy of a cold spot compensation technique using a combination of trans-rectal ultrasonography (TRUS) and computed tomography (CT) for permanent interstitial prostate brachytherapy. Material and methods: Sixty-five patients were treated with the cold spot compensation technique using TRUS-CT fusion. The prescribed dose was set at 145 Gy. The dose to 90% of prostate volume (D90 ) was planned to be within 195 Gy (134%) and 205 Gy (141%)...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619050/time-to-psa-rise-differentiates-the-psa-bounce-after-hdr-and-ldr-brachytherapy-of-prostate-cancer
#12
Wojciech Burchardt, Janusz Skowronek
Purpose: To investigate the differences in prostate-specific antigen (PSA) bounce (PB) after high-dose-rate (HDR-BT) or low-dose-rate (LDR-BT) brachytherapy alone in prostate cancer patients. Materials and methods: Ninety-four patients with localized prostate cancer (T1-T2cN0), age ranged 50-81 years, were treated with brachytherapy alone between 2008 and 2010. Patients were diagnosed with adenocarcinoma, Gleason score ≤ 7. The LDR-BT total dose was 144-145 Gy, in HDR-BT - 3 fractions of 10...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441104/current-status-of-brachytherapy-in-cancer-treatment-short-overview
#13
REVIEW
Janusz Skowronek
Cancer incidence and mortality depend on a number of factors, including age, socio-economic status and geographical location, and its prevalence is growing around the world. Most of cancer treatments include external beam radiotherapy or brachytherapy. Brachytherapy, a type of radiotherapy with energy from radionuclides inserted directly into the tumor, is increasingly used in cancer treatment. For cervical and skin cancers, it has become a standard therapy for more than 100 years as well as an important part of the treatment guidelines for other malignancies, including head and neck, skin, breast, and prostate cancers...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441103/complete-response-in-a-patient-with-gynecological-hidradenocarcinoma-treated-with-exclusive-external-beam-radiotherapy-and-brachytherapy-a-case-report
#14
Flavio Giannelli, Ilaria Chiola, Liliana Belgioia, Stefania Garelli, Alice Pastorino, Michela Marcenaro, Serafina Mammoliti, Sergio Costantini, Nicolò Bizzarri, Valerio Vellone, Salvina Barra, Renzo Corvò
Hidradenocarcinoma (HC) is a very rare disease. This case report illustrates a successful treatment of a 60-year-old woman with vulvo-vaginal localization of hidradenocarcinoma treated with external beam radiotherapy delivered by helical tomotherapy with a simultaneous integrated boost (SIB), followed by brachytherapy. External beam radiotherapy dose prescription was 50.4 Gy in 28 fractions, five fractions per week to whole pelvis (planning target volume 1 - PTV1), 60.2 Gy in 28 fractions to SIB1 (fundus of uterus and right inguinal node), and 58...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441102/dosimetric-analysis-of-rib-interference-of-the-ctv-during-interstitial-brachytherapy-of-lung-tumors
#15
Bo Yang, Xiaoyang Sun, Haowen Pang, Xiangxiang Shi, Tao Tang, Guangpeng Zhang, Renjin Chen, Jing Zhang, Hong Wu, Sheng Lin, Qinglian Wen, Yunwei Han, Jingbo Wu
Purpose: In interstitial brachytherapy for lung tumors, the placement and alignment of the source needles are influenced by the ribs, which can affect the dose distribution. This study evaluated the change in dose to the target by comparing the dose between the actual interstitial brachytherapy plan (AIBP, what is deliverable due to anatomic constraints), and the virtual interstitial brachytherapy plan (VIBP, pretreatment-modified dose distribution). Material and methods: AIBPs and VIBPs were designed for 20 lung tumors...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441101/high-dose-rate-brachytherapy-in-the-treatment-of-skin-kaposi-sarcoma
#16
María Ángeles González Ruiz, Juan Quirós Rivero, Julia Luisa Muñoz García, Joaquín José Cabrera Rodríguez, Yesika Ríos Kavadoy, María Francisca Ropero Carmona, Almudena Corbacho Campos, Fernando García Urra, María Cristina Cruz Muñoz, Amanda Ruiz Herrero, Pedro Almendral Manzano
Purpose: The aim of the study is to review our experience in treatment of Kaposi sarcoma (KS) lesions with high-dose-rate (HDR) brachytherapy. Material and methods: We present five new KS lesions (three patients) that were treated in our hospital from May 2016 to February 2017 with HDR brachytherapy using Valencia applicators. The treatment was delivered in 5 Gy fractions over five sessions, on alternate days. Total dose of 25 Gy (EQD2 31.25 Gy) was delivered. All patients were male, Caucasian, without a history of HIV, organ transplantation, or current immunosuppressive therapy...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441100/dose-volume-analysis-of-target-volume-and-critical-structures-in-computed-tomography-image-based-multicatheter-high-dose-rate-interstitial-brachytherapy-for-head-and-neck-cancer
#17
Hironori Akiyama, Tibor Major, Csaba Polgár, Zoltán Takácsi-Nagy
Purpose: To evaluate dose-volume relationships of target volume and critical structures in computed tomography (CT) image-based brachytherapy for head and neck cancer. Material and methods: Thirty-seven patients with mobile tongue, floor of mouth, and base of tongue cancer treated with brachytherapy (post-operative alone and as a boost after external beam radiotherapy [EBRT], or definitive alone or as a boost after EBRT) were selected. Treatment plans were made using post-implant CT images...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441099/ruthenium-brachytherapy-for-uveal-melanoma-single-institution-experience
#18
Iwona Rospond-Kubiak, Marta Wróblewska-Zierhoffer, Hanna Twardosz-Pawlik, Jarosław Kocięcki
Purpose: The aim of this study was to report on results of uveal melanoma treatment with ruthenium-106 (106 Ru) brachytherapy with long-term follow-up, in terms of local tumor control, eye retention rate, radiation retinopathy, and patients' survival. Material and methods: Medical records of patients treated with ruthenium plaque due to uveal melanoma at the Department of Ophthalmology, Poznan University of Medical Sciences, Poland, between 1994 and 2014 were retrospectively reviewed...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441098/nomogram-for-predicting-radiation-maculopathy-in-patients-treated-with-ruthenium-106-plaque-brachytherapy-for-uveal-melanoma
#19
Luca Tagliaferri, Monica Maria Pagliara, Carlotta Masciocchi, Andrea Scupola, Luigi Azario, Gabriela Grimaldi, Rosa Autorino, Maria Antonietta Gambacorta, Antonio Laricchiuta, Luca Boldrini, Vincenzo Valentini, Maria Antonietta Blasi
Purpose: To develop a predictive model and nomogram for maculopathy occurrence at 3 years after 106 Ru/106 Rh plaque brachytherapy in uveal melanoma. Material and methods: Clinical records of patients affected by choroidal melanoma and treated with 106 Ru/106 Rh plaque from December 2006 to December 2014 were retrospectively reviewed. Inclusion criteria were: dome-shaped melanoma, distance to the fovea > 1.5 mm, tumor thickness > 2 mm, and follow-up > 4 months...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441097/the-feasibility-of-using-ultrasound-during-follow-up-for-superficial-non-melanoma-skin-cancers-after-electronic-brachytherapy
#20
Uma Goyal, Justin Suszko, Baldassarre Stea
Purpose: Non-melanoma skin cancers (NMSCs) can be treated with a number of modalities including surgery, topical chemotherapy, or radiotherapy. Amongst the radiotherapeutic options, electronic brachytherapy (eBT) is an appealing treatment as it is usually given in a few fractions, it leads to good outcomes, and is increasingly being used. However, currently no follow-up imaging is routinely used or recommended to evaluate treatment response of NMSC. We aimed to use ultrasound (US) in follow-up after eBT for superficial NMSC to assess its feasibility in detecting possible tumor response...
December 2017: Journal of Contemporary Brachytherapy
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