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Journal of Contemporary Brachytherapy

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https://www.readbyqxmd.com/read/29441104/current-status-of-brachytherapy-in-cancer-treatment-short-overview
#1
REVIEW
Janusz Skowronek
Cancer incidence and mortality depend on a number of factors, including age, socio-economic status and geographical location, and its prevalence is growing around the world. Most of cancer treatments include external beam radiotherapy or brachytherapy. Brachytherapy, a type of radiotherapy with energy from radionuclides inserted directly into the tumor, is increasingly used in cancer treatment. For cervical and skin cancers, it has become a standard therapy for more than 100 years as well as an important part of the treatment guidelines for other malignancies, including head and neck, skin, breast, and prostate cancers...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441103/complete-response-in-a-patient-with-gynecological-hidradenocarcinoma-treated-with-exclusive-external-beam-radiotherapy-and-brachytherapy-a-case-report
#2
Flavio Giannelli, Ilaria Chiola, Liliana Belgioia, Stefania Garelli, Alice Pastorino, Michela Marcenaro, Serafina Mammoliti, Sergio Costantini, Nicolò Bizzarri, Valerio Vellone, Salvina Barra, Renzo Corvò
Hidradenocarcinoma (HC) is a very rare disease. This case report illustrates a successful treatment of a 60-year-old woman with vulvo-vaginal localization of hidradenocarcinoma treated with external beam radiotherapy delivered by helical tomotherapy with a simultaneous integrated boost (SIB), followed by brachytherapy. External beam radiotherapy dose prescription was 50.4 Gy in 28 fractions, five fractions per week to whole pelvis (planning target volume 1 - PTV1), 60.2 Gy in 28 fractions to SIB1 (fundus of uterus and right inguinal node), and 58...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441102/dosimetric-analysis-of-rib-interference-of-the-ctv-during-interstitial-brachytherapy-of-lung-tumors
#3
Bo Yang, Xiaoyang Sun, Haowen Pang, Xiangxiang Shi, Tao Tang, Guangpeng Zhang, Renjin Chen, Jing Zhang, Hong Wu, Sheng Lin, Qinglian Wen, Yunwei Han, Jingbo Wu
Purpose: In interstitial brachytherapy for lung tumors, the placement and alignment of the source needles are influenced by the ribs, which can affect the dose distribution. This study evaluated the change in dose to the target by comparing the dose between the actual interstitial brachytherapy plan (AIBP, what is deliverable due to anatomic constraints), and the virtual interstitial brachytherapy plan (VIBP, pretreatment-modified dose distribution). Material and methods: AIBPs and VIBPs were designed for 20 lung tumors...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441101/high-dose-rate-brachytherapy-in-the-treatment-of-skin-kaposi-sarcoma
#4
María Ángeles González Ruiz, Juan Quirós Rivero, Julia Luisa Muñoz García, Joaquín José Cabrera Rodríguez, Yesika Ríos Kavadoy, María Francisca Ropero Carmona, Almudena Corbacho Campos, Fernando García Urra, María Cristina Cruz Muñoz, Amanda Ruiz Herrero, Pedro Almendral Manzano
Purpose: The aim of the study is to review our experience in treatment of Kaposi sarcoma (KS) lesions with high-dose-rate (HDR) brachytherapy. Material and methods: We present five new KS lesions (three patients) that were treated in our hospital from May 2016 to February 2017 with HDR brachytherapy using Valencia applicators. The treatment was delivered in 5 Gy fractions over five sessions, on alternate days. Total dose of 25 Gy (EQD2 31.25 Gy) was delivered. All patients were male, Caucasian, without a history of HIV, organ transplantation, or current immunosuppressive therapy...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441100/dose-volume-analysis-of-target-volume-and-critical-structures-in-computed-tomography-image-based-multicatheter-high-dose-rate-interstitial-brachytherapy-for-head-and-neck-cancer
#5
Hironori Akiyama, Tibor Major, Csaba Polgár, Zoltán Takácsi-Nagy
Purpose: To evaluate dose-volume relationships of target volume and critical structures in computed tomography (CT) image-based brachytherapy for head and neck cancer. Material and methods: Thirty-seven patients with mobile tongue, floor of mouth, and base of tongue cancer treated with brachytherapy (post-operative alone and as a boost after external beam radiotherapy [EBRT], or definitive alone or as a boost after EBRT) were selected. Treatment plans were made using post-implant CT images...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441099/ruthenium-brachytherapy-for-uveal-melanoma-single-institution-experience
#6
Iwona Rospond-Kubiak, Marta Wróblewska-Zierhoffer, Hanna Twardosz-Pawlik, Jarosław Kocięcki
Purpose: The aim of this study was to report on results of uveal melanoma treatment with ruthenium-106 ( 106 Ru) brachytherapy with long-term follow-up, in terms of local tumor control, eye retention rate, radiation retinopathy, and patients' survival. Material and methods: Medical records of patients treated with ruthenium plaque due to uveal melanoma at the Department of Ophthalmology, Poznan University of Medical Sciences, Poland, between 1994 and 2014 were retrospectively reviewed...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441098/nomogram-for-predicting-radiation-maculopathy-in-patients-treated-with-ruthenium-106-plaque-brachytherapy-for-uveal-melanoma
#7
Luca Tagliaferri, Monica Maria Pagliara, Carlotta Masciocchi, Andrea Scupola, Luigi Azario, Gabriela Grimaldi, Rosa Autorino, Maria Antonietta Gambacorta, Antonio Laricchiuta, Luca Boldrini, Vincenzo Valentini, Maria Antonietta Blasi
Purpose: To develop a predictive model and nomogram for maculopathy occurrence at 3 years after 106 Ru/ 106 Rh plaque brachytherapy in uveal melanoma. Material and methods: Clinical records of patients affected by choroidal melanoma and treated with 106 Ru/ 106 Rh plaque from December 2006 to December 2014 were retrospectively reviewed. Inclusion criteria were: dome-shaped melanoma, distance to the fovea > 1.5 mm, tumor thickness > 2 mm, and follow-up > 4 months...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441097/the-feasibility-of-using-ultrasound-during-follow-up-for-superficial-non-melanoma-skin-cancers-after-electronic-brachytherapy
#8
Uma Goyal, Justin Suszko, Baldassarre Stea
Purpose: Non-melanoma skin cancers (NMSCs) can be treated with a number of modalities including surgery, topical chemotherapy, or radiotherapy. Amongst the radiotherapeutic options, electronic brachytherapy (eBT) is an appealing treatment as it is usually given in a few fractions, it leads to good outcomes, and is increasingly being used. However, currently no follow-up imaging is routinely used or recommended to evaluate treatment response of NMSC. We aimed to use ultrasound (US) in follow-up after eBT for superficial NMSC to assess its feasibility in detecting possible tumor response...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441096/implantation-of-computed-tomography-guided-iodine-125-seeds-in-combination-with-chemotherapy-for-the-treatment-of-stage-iii-non-small-cell-lung-cancer
#9
Xiaodong Huo, Bin Huo, Huixing Wang, Lei Wang, Qiang Cao, Guangjun Zheng, Junjie Wang, Shude Chai, Zuncheng Zhang, Kuo Yang, Yuanjie Niu, Haitao Wang
Purpose: We investigated the role of computed tomography (CT)-guided Iodine-125 ( 125 I) seed implantation in combination with chemotherapy for the treatment of stage III non-small cell lung carcinoma (NSCLC). Material and methods: The data from 182 patients with stage III NSCLC who were treated with radioactive 125 I seed implantation between June 2002 and June 2009, and who received sequential platinum-based combination chemotherapy using the most common combination of platinum and gemcitabine, were retrospectively reviewed...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441095/off-line-magnetic-resonance-imaging-navigation-of-cervix-cancer-brachytherapy-in-patients-with-risk-factors-for-uterine-perforation
#10
Noora Mohammed Al-Hammadi, Suparna Halsnad Chandramouli, Rabih Hammoud, Primoz Petric
Purpose: There are no reports on pre-insertion identification of cervix cancer patients at risk for uterine perforation during brachytherapy (BT). Our aim was to assess the incidence of risk factors in our patient cohort, and assess feasibility of a novel technique of magnetic resonance imaging (MRI)-guided navigation for applicator insertion (NAI) in high-risk cases. Material and methods: All patients with locally advanced cervical cancer, treated with image guided adaptive BT at our department between October 2013 and June 2017 were considered for analysis...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441094/artificial-neural-network-based-gynaecological-image-guided-adaptive-brachytherapy-treatment-planning-correction-of-intra-fractional-organs-at-risk-dose-variation
#11
Ramin Jaberi, Zahra Siavashpour, Mahmoud Reza Aghamiri, Christian Kirisits, Reza Ghaderi
Purpose: Intra-fractional organs at risk (OARs) deformations can lead to dose variation during image-guided adaptive brachytherapy (IGABT). The aim of this study was to modify the final accepted brachytherapy treatment plan to dosimetrically compensate for these intra-fractional organs-applicators position variations and, at the same time, fulfilling the dosimetric criteria. Material and methods: Thirty patients with locally advanced cervical cancer, after external beam radiotherapy (EBRT) of 45-50 Gy over five to six weeks with concomitant weekly chemotherapy, and qualified for intracavitary high-dose-rate (HDR) brachytherapy with tandem-ovoid applicators were selected for this study...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441093/correlations-of-post-implant-regional-dosimetric-parameters-at-24-hours-and-one-month-with-clinical-results-of-low-dose-rate-brachytherapy-for-localized-prostate-cancer
#12
Eiichiro Okazaki, Katsuyuki Kuratsukuri, Kentaro Ishii, Tomoaki Tanaka, Ryo Ogino, Tomohiro Nishikawa, Hideyuki Morimoto, Masako Hosono, Yukio Miki
Purpose: To evaluate the correlations of post-implant regional dosimetrics at 24 hours (24 h) and 1 month after implant procedures, with clinical outcomes of low-dose-rate (LDR) brachytherapy for localized prostate cancer. Material and methods: Between January 2008 and December 2014, 130 consecutive patients treated for localized prostate cancer, receiving definitive iodine-125 ( 125 I) brachytherapy treatment were retrospectively analyzed. All patients underwent post-implant CT imaging for dosimetric analysis at 24 h and 1 month after implantation procedure...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441092/is-an-interventional-oncology-center-an-advantage-in-the-service-of-cancer-patients-or-in-the-education-the-gemelli-hospital-and-interacts-experience
#13
EDITORIAL
György Kovács, Luca Tagliaferri, Vincenzo Valentini
No abstract text is available yet for this article.
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29204171/magnetic-resonance-imaging-metal-artifact-reduction-for-eye-plaque-patient-with-dental-braces
#14
H Michael Gach, Stacie L Mackey, Sana Rehman, Mo Kadbi, Jacqueline E Zoberi, Jose Garcia-Ramirez, Perry W Grigsby
Purpose: To determine if metal artifact reduction can minimize magnetic susceptibility artifacts in the orbits for an eye plaque brachytherapy patient with metallic dental braces. Material and methods: A 62-year-old female patient with a choroidal melanoma in the right eye received a 1.5 T magnetic resonance imaging (MRI) simulation for 3D eye plaque brachytherapy planning. The protocol included conventional 3D T1-weighted and 2D T2-weighted MRIs. A vendor-supplied T2-weighted metal artifact reduction sequence was added to the protocol to reduce magnetic susceptibility artifacts from the metallic dental braces...
October 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29204170/locally-advanced-squamous-cell-cervical-cancer-in-a-patient-with-septate-uterus
#15
Guler Yavas, Cagdas Yavas, Gokcen Inan
A 33-year-old premenopausal multiparous woman with the history of septate uterus was referred to the hospital with menorrhagia and inter-menstrual bleeding occurring for the last 6 months. Work-up revealed a stage IIB cervical cancer. The patient underwent curative chemo/radiotherapy. The patient's septate uterus presented several difficulties during application. Brachytherapy was applied using standard computed tomography-compatible tandem and ovoids. The high-risk clinical target volume (HR-CTV), intermediate risk CTV, and organs at risk were contoured according to the Groupe Européen de Curiethérapie - European Society for Radiology and Oncology (GEC-ESTRO) guidelines...
October 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29204169/independent-assessment-of-source-position-for-gynecological-applicator-in-high-dose-rate-brachytherapy
#16
Hiroyuki Okamoto, Satoshi Nakamura, Shie Nishioka, Kotaro Iijima, Akihisa Wakita, Yukinao Abe, Naoki Tohyama, Shinji Kawamura, Toshiyuki Minemura, Jun Itami
Purpose: The aim of this study is to describe a phantom designed for independent examination of a source position in brachytherapy that is suitable for inclusion in an external auditing program. Material and methods: We developed a phantom that has a special design and a simple mechanism, capable of firmly fixing a radiochromic film and tandem-ovoid applicators to assess discrepancies in source positions between the measurements and treatment planning system (TPS)...
October 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29204168/pre-plan-technique-feasibility-in-multi-interstitial-endocavitary-perineal-gynecological-brachytherapy
#17
Silvia Rodriguez, Antonio Otal, Jose Richart, Jose Perez-Calatayud, Manuel Santos
Purpose: To present the implementation of a magnetic resonance imaging (MRI) pre-planning technique in multi-interstitial perineal and endocavitary gynecological brachytherapy. Material and methods: We used a new fully MRI-compatible applicator that is capable to engage titanium needles, and an intrauterine tandem, developed in our department for the treatment of gynecological cervical cancer patients. This applicator is an attempt to combine the technical advantages of the Martinez universal perineal interstitial template (MUPIT) with the improvement in dose distribution by adding an intrauterine probe with the imaging advantages of MRI-based brachytherapy, thus preserving the stability, geometry, and robustness of the implant, avoiding possible errors of free-hand needle placement...
October 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29204167/interstitial-brachytherapy-for-orbital-soft-tissue-sarcoma-an-innovative-technique
#18
Siddhartha Laskar, Avinash Pilar, Nehal Khanna, Yogesh Ghadi
Purpose: To report an innovative technique of interstitial brachytherapy developed for treatment of orbital soft tissue tumors. Material and methods: A 4-month-old child diagnosed with rhabdomyosarcoma of orbit was treated with multiagent chemotherapy (CTh) and brachytherapy. Pre-planning computed tomography (CT) images were obtained and clinical target volume (CTV) was defined using the pre-treatment magnetic resonance imaging (MRI). Brachytherapy plan was generated for deciding optimal catheter placement...
October 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29204166/patterns-of-care-and-survival-outcomes-after-treatment-for-uveal-melanoma-in-the-post-coms-era-2004-2013-a-surveillance-epidemiology-and-end-results-analysis
#19
Yuan James Rao, Julia Sein, Shahed Badiyan, Julie K Schwarz, Todd DeWees, Perry Grigsby, Prabakar Kumar Rao
Purpose: The Collaborative Ocular Melanoma Study (COMS) established modern treatment recommendations for uveal melanoma. We aim to evaluate patterns of care and survival outcomes in the time after COMS. Material and methods: The retrospective study population includes 2,611 patients in the SEER database treated for uveal melanoma between 2004-2013. Patients stage were T1-4N0M0. Data analyzed included age, clinical stage, tumor size, race, and treatment. Treatments included enucleation (EN) and globe preserving therapy (GPT), which consisted of limited surgical resection or ablation (LSRA), external beam radiation (EBRT), or brachytherapy (BT)...
October 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29204165/throwing-the-dart-blind-folded-comparison-of-computed-tomography-versus-magnetic-resonance-imaging-guided-brachytherapy-for-cervical-cancer-with-regard-to-dose-received-by-the-actual-targets-and-organs-at-risk
#20
Winnie Wing Ling Yip, Joyce Siu Yu Wong, Venus Wan Yan Lee, Frank Chi Sing Wong, Stewart Yuk Tung
Purpose: Computed tomography (CT) is inferior to magnetic resonance imaging (MRI) in cervical tumor delineation, but similar in identification of organs at risk (OAR). The trend to over-estimate high-risk and low-risk clinical target volume (HRCTV, IRCTV) on CT can lead to under-estimation of dose received by 90% (D90) of the 'actual' CTV. This study aims to evaluate whether CT-guided planning delivers adequate dose to the 'actual' targets while spares the OAR similarly. Material and methods: MRI-guided high-dose-rate image-guided brachytherapy (IGBT) was performed in 11 patients...
October 2017: Journal of Contemporary Brachytherapy
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