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Journal of Contemporary Brachytherapy

Naveen Mummudi, Shivakumar Gudi, Rajendra Bhalavat, Umesh Mahantshetty
No abstract text is available yet for this article.
August 2018: Journal of Contemporary Brachytherapy
Kanchan P Dholam, Gurkaran Preet Singh, Sarbani Ghosh Laskar, Sandeep V Gurav, Gorakh S Ahire
Brachytherapy has been widely employed as a salvage or adjuvant modality in localized early and/or recurrent lesions. In recent years, advances in brachytherapy techniques have helped to achieve better loco-regional disease control and higher survival rates at the cost of limited morbidity. This is mainly owing to the development of technologically advanced three-dimensional computer planning systems and treatment delivery techniques. Low-dose-rate brachytherapy has been substituted by high-dose-rate and pulsed-dose-rate techniques, which allow better dose optimization...
August 2018: Journal of Contemporary Brachytherapy
Xiaodong Ma, Prof Zhiyong Yang, Prof Shan Jiang, Prof Bin Huo, Qiang Cao, Prof Shude Chai, Prof Haitao Wang
Purpose: This research aims to evaluate the effectiveness and safety of a robot-assisted 3D personalized template in 125 I seed brachytherapy of thoracoabdominal tumors. Material and methods: Forty-three patients with different tumors were involved in this research between 2013 and 2015. They were all eligible to 125 I seed implantation based on robot-assisted 3D personalized template. Meanwhile, 51 patients with similar tumors, which were treated with a conventional coplanar template, were involved for comparison...
August 2018: Journal of Contemporary Brachytherapy
Jie Li, Lijuan Zhang, Qigen Xie, Weiguo Wang, Yanyan Hua, Zongqiong Sun
Purpose: To evaluate the efficacies of 125 I seed implantation and stereotactic body radiation therapy (SBRT) in treatment of recurrent lung metastases from colorectal cancer, to compare the tolerance of lung tissue to both forms of radiotherapy, and to analyze the factors that affect the prognosis. Material and methods: According to treatment received, thirty colorectal cancer patients with post-operative lung metastases were separated into two groups: 125 I seed implantation group (group A; n = 16) and SBRT group (group B; n = 14)...
August 2018: Journal of Contemporary Brachytherapy
David Miguel, Jesús María de Frutos-Baraja, Francisco López-Lara, María Antonia Saornil, Ciro García-Álvarez, Pilar Alonso, Patricia Diezhandino
Purpose: To assess the influence of the radiobiological doses, tumor, and treatment features on retinopathy, cataracts, retinal detachment, optic neuropathy, vitreous hemorrhage, and neovascular glaucoma at the authors' institution after brachytherapy for posterior uveal melanoma. Material and methods: Medical records of 243 eyes with uveal melanoma, treated by iodine brachytherapy between 1996 and 2016 at a single center were analyzed. Clinical and radiotherapy data were extracted from a dedicated database...
August 2018: Journal of Contemporary Brachytherapy
David Miguel, Jesús María de Frutos-Baraja, Francisco López-Lara, María Antonia Saornil, Ciro García-Álvarez, Pilar Alonso, Patricia Diezhandino
Purpose: To assess influence of the radiobiological doses, tumor, and treatment features on local control, enucleation rates, overall and disease-specific survival rates after brachytherapy for posterior uveal melanoma. Material and methods: Local control, enucleation, overall and disease-specific survival rates were evaluated on the base of 243 patients from 1996 through 2016, using plaques loaded with iodine sources. Clinical and radiotherapy data were extracted from a dedicated prospective database...
August 2018: Journal of Contemporary Brachytherapy
Bikramjit Chakrabarti, Suparna Kanti Pal, Harris Mahammad Sepai, Somapriya Basu Roy, Sanjay Kr Kar, Annesha Lahiri, Sounik Das, Amit Bala
Purpose: This study analyzes clinical consequences and dosimetric variations after imperfect brachytherapy insertions. It examines treatment decisions after such insertions in patients having difficult anatomy, which leads to good subsequent insertions with acceptable dose volume parameters. Material and methods: We reviewed images of all insertions performed during last one year and sorted faulty ones out. Clinical outcome was assessed, analyzing original treatment records...
August 2018: Journal of Contemporary Brachytherapy
Rosa Autorino, Luca Tagliaferri, Maura Campitelli, Daniela Smaniotto, Alessia Nardangeli, Gian Carlo Mattiucci, Gabriella Macchia, Benedetta Gui, Maura Miccò, Floriana Mascilini, Gabriella Ferrandina, Gyorgy Kovacs, Vincenzo Valentini, Maria Antonietta Gambacorta
Purpose: To compare the survival and toxicity outcomes in patients with endometrial cancer treated with either high-dose-rate (HDR) or low-dose-rate (LDR) vaginal brachytherapy (VBT) following external beam radiotherapy (EBRT). Material and methods: From January 2000 to December 2014, patients with endometrial cancer after radical hysterectomy with/without pelvic and/or para-aortic lymphadenectomy were treated with adjuvant EBRT (45 Gy, 1.8 Gy/day to the whole pelvis) and subsequent VBT boost (HDR dose of 7 Gy in one fraction or LDR VBT dose of 25 Gy)...
August 2018: Journal of Contemporary Brachytherapy
Matthew Sean Peach, Joanna Moore, Wallis Giles, Justin Trainor, Tim Long, Nicholas Moon, Joseph E Hylton, Timothy N Showalter, Bruce Libby
Purpose: We evaluated the performance of a novel hydrogel-based strategy developed for clinical use as vaginal packing using phantoms and cadavers, and to compare the hydrogel to gauze and balloon packing. Material and methods: The biocompatible hydrogel is based on a thiol-Michael addition reaction, with delivery of reagents into the vaginal cavity using a custom-made system. Soft-cured cadavers were used for soft tissue-like mechanical properties. Two cadavers with intact uteri had magnetic resonance imaging (MRI) compatible with tandem and ovoids...
August 2018: Journal of Contemporary Brachytherapy
Jörg S Zimmermann, Rudolf Osieka, Thorsten Bruns, Helge Hollberg, Bastian Wiechmann, Olaf Netzbandt, Jörg Sablotny, Michael Malade, Matthias Heitz, Fritz Bernhardt, Jörg Tiemann, Marc Wilkens, Tom Brüske, Utz Welker, Volker Heinemann, Petra Zimmermann, Salvador Fernandez de la Maza, Dietrich Pfeiffer, Prof Roland Tauber, Dorothea Thomas, Christos Moustakis
Purpose: To assess the effectiveness of low-dose-rate (LDR) brachytherapy in patients with localized prostate cancer and to compare the outcome with predictions from Kattan and Partin nomograms at 60 months after seed implantation. Material and methods: One thousand, one hundred and eighty-seven patients with localized prostate cancer at low-, intermediate-, or high-risk of progression received LDR brachytherapy using iodine-125 seeds with curative intent, applied as monotherapy or in combination with external beam radiation therapy (EBRT), and/or androgen deprivation therapy (ADT)...
August 2018: Journal of Contemporary Brachytherapy
Tomoya Kaneda, Toshio Ohashi, Masanori Sakayori, Shinya Sutani, Shoji Yamashita, Tetsuo Momma, Shinichi Takahashi, Takashi Hanada, Naoyuki Shigematsu
Purpose: Few studies have compared the implant quality of linked and loose seeds for prostate brachytherapy. This study aimed to evaluate and compare plan reproducibility of intraoperatively built custom linked seeds and loose seeds for prostate brachytherapy. Material and methods: Between December 2010 and March 2014, 76 localized prostate cancer patients received Iodine-125 brachytherapy with external beam radiotherapy. Linked and loose seeds were implanted in 39 and 37 patients, respectively...
August 2018: Journal of Contemporary Brachytherapy
Simone Grisotto, Annamaria Cerrotta, Brigida Pappalardi, Mauro Carrara, Antonella Messina, Chiara Tenconi, Riccardo Valdagni, Carlo Fallai
Purpose: The purpose of this study was to compare the prostate contours drawn by two radiation oncologists and one radiologist on magnetic resonance (MR) and transrectal ultrasound (TRUS) images. TRUS intra- and inter-fraction variability as well as TRUS vs. MR inter-modality and inter-operator variability were studied. Material and methods: Thirty patients affected by localized prostate cancer and treated with interstitial high-dose-rate (HDR) prostate brachytherapy at the National Cancer Institute in Milan were included in this study...
August 2018: Journal of Contemporary Brachytherapy
Cheng Huang, Mingyuan He, Hongfu Zhao, Prof Guanghui Cheng
The aim of this study is to report an uncommon case of nasal keloid treated with adaptive image-guided high-dose-rate (HDR) intracavitary brachytherapy. A 34-year-old female presented with nasal keloid after facial trauma was treated with scar resection and HDR intracavitary brachytherapy with a customized eccentric applicator. The total dose was 21 Gy in 6 fractions. During 3 years of follow-up, there was no evidence of recurrence at the local site, and no complications. In conclusion, HDR intracavitary brachytherapy is an effective way to prevent the recurrence of nasal keloids post-surgery...
June 2018: Journal of Contemporary Brachytherapy
Ken Yoshida, Yuki Otani, Takayuki Nose, Eisaku Yoden, Shuuji Asahi, Iwao Tsukiyama, Takushi Dokiya, Toshiaki Saeki, Ichirou Fukuda, Hiroshi Sekine, Yu Kumazaki, Takao Takahashi, Tadayuki Kotsuma, Norikazu Masuda, Kazutaka Nakashima, Taisei Matsumura, Shino Nakagawa, Seiji Tachiiri, Yoshio Moriguchi, Jun Itami, Masahiko Oguchi
We initiated the first multi-institutional prospective study of accelerated partial breast irradiation for early breast cancer in Japan. Our early clinical results showed that the treatment methods were technically reproducible between institutions and showed excellent disease control at a median follow-up of 26 months in our previous report. At present, total 46 patients from six institutions underwent the treatment regimen from October 2009 to December 2011, and the median follow-up time was 60 months (range, 57-67 months)...
June 2018: Journal of Contemporary Brachytherapy
Yuting Gao, Ning Wu, Zhipeng Zhao, Mingyuan He, Jie Han, Guanghui Cheng
Purpose: The aim of the report was the evaluation of application with image-guided high-dose-rate (HDR) interstitial brachytherapy in patients undergoing conventional chemo-radiotherapy for perineal locally recurrent rectal cancer (LRRC). Material and methods: 75-year-old female patient presented with LRRC three years after total mesorectal excision (TME) surgery for rectal cancer with tubular adenocarcinoma (stage IIIB). Despite conventional chemotherapy and external beam radiotherapy, the re-recurrent lesion expanded as 4...
June 2018: Journal of Contemporary Brachytherapy
Luca Tagliaferri, Ashwini Budrukkar, Jacopo Lenkowicz, Mauricio Cambeiro, Francesco Bussu, Jose Luis Guinot, Guido Hildebrandt, Bengt Johansson, Jens E Meyer, Peter Niehoff, Angeles Rovirosa, Zoltán Takácsi-Nagy, Luca Boldrini, Nicola Dinapoli, Vito Lanzotti, Andrea Damiani, Roberto Gatta, Bruno Fionda, Valentina Lancellotta, Tamer Soror, Rafael Martìnez Monge, Vincenzo Valentini, György Kovács
Purpose: Clinical data collecting is expensive in terms of time and human resources. Data can be collected in different ways; therefore, performing multicentric research based on previously stored data is often difficult. The primary objective of the ENT COBRA (COnsortium for BRachytherapy data Analysis) ontology is to define a specific terminological system to standardized data collection for head and neck (H&N) cancer patients treated with interventional radiotherapy. Material and methods: ENT-COBRA is a consortium for standardized data collection for H&N patients treated with interventional radiotherapy...
June 2018: Journal of Contemporary Brachytherapy
Rosa Autorino, Lisa Vicenzi, Luca Tagliaferri, Carlo Soatti, Prof Gyeorgy Kovacs, Cynthia Aristei
Purpose: To review brachytherapy resources and to explore current practice patterns in Italy. Material and methods: In 2016, on behalf of the Italian Association of Radiation Oncology (AIRO), the Brachytherapy Study Group proposed conducting a survey in order to identify brachytherapy practice patterns. An electronic questionnaire was sent to all radiotherapy centres in Italy, asking for: 1. General information on the Radiation Oncology Centre (affiliation, whether brachytherapy was delivered or not); 2...
June 2018: Journal of Contemporary Brachytherapy
Rezarta Frakulli, Milly Buwenge, Silvia Cammelli, Gabriella Macchia, Eleonora Farina, Alessandra Arcelli, Martina Ferioli, Lorenzo Fuccio, Luca Tagliaferri, Andrea Galuppi, Giovanni P Frezza, Alessio G Morganti
Radio-chemotherapy (RCT) is the primary treatment of anal cancer (AC). However, the role and the optimal total dose of a radiation boost is still unclear. No randomized controlled trials nor systematic reviews have been performed to analyze the efficacy of brachytherapy (BRT) as boost in AC. Therefore, we performed this systematic review based on PRISMA methodology to establish the role of BRT boost in AC. A systematic search of the bibliographic databases: PubMed, Scopus, and Cochrane library from the earliest possible date through January 31, 2018 was performed...
June 2018: Journal of Contemporary Brachytherapy
Gemma Corey, A B Mohamed Yoosuf, Geraldine Workman, Monica Byrne, Darren M Mitchell, Suneil Jain
Purpose: To document the current prostate brachytherapy practice across the UK and Ireland and compare with previously published audit results. Material and methods: Participants from 25 centers attending the annual UK & Ireland Prostate Brachytherapy Conference were invited to complete an online survey. Sixty-three questions assessed the center's experience and staffing, clinician's experience, clinical selection criteria and scheduling, number of cases per modality in the preceding three years, low-dose-rate (LDR) pre- and post-implant technique and high-dose-rate (HDR) implant technique...
June 2018: Journal of Contemporary Brachytherapy
Corinna Melchert, Tamer Soror, György Kovács
Purpose: Brachytherapy procedure may result in acute tissue reactions like edema, causing deviations between planned and measured doses. The rationale for in vivo dosimetry in interstitial brachytherapy is to assess the accuracy of the delivered dose in comparison with the dose calculated by the treatment planning system (TPS). Material and methods: One single computer tomography (CT) dataset was used for brachytherapy planning, taken within 24 hours after implantation...
June 2018: Journal of Contemporary Brachytherapy
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