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Journal of Contemporary Brachytherapy

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https://www.readbyqxmd.com/read/29795720/ruthenium-brachytherapy-for-intraocular-growth-of-a-conjunctival-squamous-cell-carcinoma-a-case-report
#1
Iwona Rospond-Kubiak, Wojciech Adamski, Kinga Sosnowska, Jarosław Kociȩcki, Andrzej Marszałek
The aim of this study is to report the use of ruthenium brachytherapy as an adjunctive treatment in the management of an intraocular extension of the conjunctival squamous cell carcinoma (SCC). In 2013, a 73-year-old man presented with a tumor blocking the angle and infiltrating corneal endothelium. The patient was treated with iridectomy, and after one month, ruthenium brachytherapy was applied. 4.5 years post-irradiation, the treated eye is painless, and no recurrence was noted. We advocate the use of ruthenium brachytherapy as an eye salvage treatment with an intraocular extension of conjunctival SCC...
April 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29789768/radiological-and-clinical-findings-following-rectal-contact-x-ray-brachytherapy-papillon-technique-how-to-assess-response
#2
Matt J D Dunstan, Tim A Rockall, Kate Potter, Alexandra J Stewart
Purpose: Rectal contact X-ray brachytherapy (Papillon radiotherapy) has recently received approval from the National Institute for Health and Care Excellence. In particular, it is suitable for elderly patients who are high-risk for a major operation, but it may also be undertaken for patients who wish to avoid a stoma. It is imperative to be able to identify clinical response or tumor regrowth on surveillance magnetic resonance imaging (MRI) and sigmoidoscopy. This article aims to help clinicians to interpret MRIs and endoscopic appearances following Papillon radiotherapy...
April 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29789767/don-t-forget-the-bladder
#3
Bernard J Oosterveld, Elzbieta M van der Steen-Banasik, Geert A Smits
No abstract text is available yet for this article.
April 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29789766/salvage-high-dose-rate-brachytherapy-for-prostate-cancer-persistence-after-brachytherapy-repeated-use-of-a-polyethylene-glycol-hydrogel-spacer
#4
Rodrigo Hepp, Thilo Eggert, Georg Schabl, Lars Herberholz, Tim Petry, Razvan Galalae
Purpose: The aim of this study is to determine if a repeated hydrogel injection in a previously irradiated patient prior to salvage high-dose-rate brachytherapy (HDR-BT) is feasible. Material and methods: A 61-year-old man with an organ confined (cT1c cN0 cM0, Gleason score 3 + 3 = 6, initial prostate-specific antigen [PSA] 7.9 ng/ml) prostate cancer was previously treated with HDR-BT (3 fractions of 11.5 Gy every 2nd week) after hydrogel injection to reduce the rectal dose...
April 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29789765/successful-salvage-treatment-of-refractory-recurrence-of-maxillary-sinus-carcinoma-using-image-guided-high-dose-rate-interstitial-brachytherapy
#5
Yin Zhang, Ning Wu, Zhipeng Zhao, Qianqian Chen, Guanghui Cheng
This case report illustrates a treatment effect of image-guided high-dose-rate (HDR) interstitial brachytherapy for refractory recurrence of maxillary sinus carcinoma. A 61-year-old male was previously admitted to another hospital and received surgery because of left maxillary sinus squamous cell carcinoma (SCC) 6 years ago. Tumor regrowth was noted 2 years after the initial radical surgery. The patient accepted local excision again for the recurrence, followed by external beam radiotherapy. Despite salvage treatment with surgery and external irradiation, the lesion expanded as 4...
April 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29789764/a-single-institution-analysis-of-low-dose-rate-brachytherapy-5-year-reported-survival-and-late-toxicity-outcomes
#6
REVIEW
Michael Chao, Sandra Spencer, Mario Guerrieri, Wei Ding, Mehran Goharian, Huong Ho, Michael Ng, Danielle Healey, Alwin Tan, Chee Cham, Daryl Lim Joon, Nathan Lawrentschuk, Douglas Travis, Shomik Sengupta, Yee Chan, Andrew Troy, Trung Pham, David Clarke, Peter Liodakis, Damien Bolton
Purpose: To report the 5-year biochemical relapse-free survival (BRFS), overall survival (OS), and long-term toxicity outcomes of patients treated with low-dose-rate (LDR) brachytherapy as monotherapy for low- to intermediate-risk prostate cancer. Material and methods: Between 2004 and 2011, 371 patients were treated with LDR brachytherapy as monotherapy. Of these, 102 patients (27%) underwent transurethral resection of the prostate (TURP) prior to implantation...
April 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29789763/verification-of-high-dose-rate-brachytherapy-treatment-planning-dose-distribution-using-liquid-filled-ionization-chamber-array
#7
A B Mohamed Yoosuf, Prakash Jeevanandam, Glenn Whitten, Geraldine Workman, Conor K McGarry
Purpose: This study aims to investigate the dosimetric performance of a liquid-filled ionization chamber array in high-dose-rate (HDR) brachytherapy dosimetry. A comparative study was carried out with air-filled ionization chamber array and EBT3 Gafchromic films to demonstrate its suitability in brachytherapy. Material and methods: The PTW OCTAVIUS detector 1000 SRS (IA 2.5-5 mm) is a liquid-filled ionization chamber array of area 11 x 11 cm2 and chamber spacing of 2...
April 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29789762/percutaneous-computed-tomography-guided-permanent-125-i-implantation-as-therapy-for-pulmonary-metastasis
#8
Xiaodong Huo, Bin Huo, Huixing Wang, Lei Wang, Qiang Cao, Guangjun Zheng, Junjie Wang, Shude Chai, Zuncheng Zhang, Kuo Yang, Yuanjie Niu, Haitao Wang
Purpose: To evaluate intermediate-term outcomes after computed tomography (CT)-guided radioactive 125 I seed implantation (CTRISI), and to determine prognostic variables associated with outcomes in patients with pulmonary metastases. Material and methods: Thoracic surgeons evaluated and performed implantation of 125 I radioactive seeds under CT guidance or combined with surgical resection. Patients were monitored in the thoracic surgery clinic for recurrence and survival...
April 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29789761/visual-outcome-after-posterior-uveal-melanoma-episcleral-brachytherapy-including-radiobiological-doses
#9
David Miguel, Jesús María de Frutos-Baraja, Francisco López-Lara, María Antonia Saornil, Ciro García-Alvarez, Pilar Alonso, Patricia Diezhandino
Purpose: To assess the long-term influence of radiobiological doses in the evolution of visual acuity (VA) in patients with uveal melanoma treated by episcleral brachytherapy. Material and methods: Visual acuity was evaluated prospectively from a case series of 243 patients in 2016 treated with 125 I. Data analysis was applied to trend VA outcome and find the accurate best-fit line. Biologically effective dose (BED) was included in survival analysis with the use of Kaplan-Meier and Cox regressions...
April 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29789760/high-dose-rate-brachytherapy-in-treatment-of-non-melanoma-skin-cancer-of-head-and-neck-region-preliminary-results-of-a-prospective-single-institution-study
#10
Bita Kalaghchi, Ebrahim Esmati, Reza Ghalehtaki, Marzieh Gomar, Ramin Jaberi, Soraya Gholami, Somayyeh Babaloui, Mansoureh Nabavi, Sarvazad Sotoudeh, Nezhat Khanjani, Ali Kazemian, Farnaz Amouzegar-Hashemi, Mahdi Aghili, Marzieh Lashkari
Purpose: Skin cancers are the most common human malignancy with increasing incidence. Currently, surgery is standard of care treatment for non-melanoma skin cancers. However, brachytherapy is a growing modality in the management of skin cancers. Therefore, we aimed to assess the outcome of patients with non-melanoma skin cancers treated by high-dose-rate (HDR) brachytherapy with surface mold technique. Material and methods: In this prospective study, we recruited patients with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) of the skin who were candidates for definitive or adjuvant brachytherapy during 2013-2014...
April 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29789759/combined-external-beam-radiotherapy-and-vaginal-brachytherapy-versus-vaginal-brachytherapy-in-stage-i-intermediate-and-high-risk-cases-of-endometrium-carcinoma
#11
R A Sunil, Devang Bhavsar, M N Shruthi, U Suryanarayan Kunikullaya, R K Vyas, Ankita Parikh, Maitrik Jayantkumar Mehta, Pooja Nandwani Patel
Purpose: Randomized trials on the effect of external beam radiotherapy (EBRT) with or without vaginal brachytherapy (VBT) for endometrial carcinoma are very few. In view of this, the current study was conducted with the hypothesizes: whether the escalated dose of 26 Gy (VBT alone) in comparison with various major international trials (PORTEC-2) has any difference in rates of disease-free and overall survival with fewer adverse effects in low resource setting like India. Material and methods: An open-labeled, non-inferiority, randomized control trial was undertaken at a regional cancer center among patients with stage IA or IB high-intermediate risk endometrial carcinoma...
April 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29789758/advantages-of-intraoperative-implant-for-interstitial-brachytherapy-for-accelerated-partial-breast-irradiation-either-frail-patients-with-early-stage-disease-or-in-locally-recurrent-breast-cancer
#12
Salvatore Cozzi, Maria Laplana, Dina Najjari, Andrea Slocker, Xavier Encinas, Joan Pera, Ferran Guedea, Cristina Gutierrez
Purpose: To describe the intraoperative multicatheter implantation technique for accelerated partial breast irradiation (APBI) delivered with high-dose-rate brachytherapy (HDR-BT). Secondarily, to evaluate outcomes and toxicity in a series of 83 patients treated with this technique at our institution. Material and methods: Retrospective analysis of a series of patients treated with HDR-BT APBI after intraoperative multicatheter interstitial implant between November 2006 and June 2017 at our institution...
April 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619061/the-effect-of-tandem-ovoid-titanium-applicator-on-points-a-b-bladder-and-rectum-doses-in-gynecological-brachytherapy-using-192-ir
#13
Mohammad Hosein Sadeghi, Sedigheh Sina, Amir Mehdizadeh, Reza Faghihi, Vahed Moharramzadeh, Ali Soleimani Meigooni
Purpose: The dosimetry procedure by simple superposition accounts only for the self-shielding of the source and does not take into account the attenuation of photons by the applicators. The purpose of this investigation is an estimation of the effects of the tandem and ovoid applicator on dose distribution inside the phantom by MCNP5 Monte Carlo simulations. Material and methods: In this study, the superposition method is used for obtaining the dose distribution in the phantom without using the applicator for a typical gynecological brachytherapy (superposition-1)...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619060/reduction-of-applicator-displacement-in-mr-ct-guided-cervical-cancer-hdr-brachytherapy-by-the-use-of-patient-hover-transport-system
#14
Megan Andrew, Yusung Kim, Timothy Ginader, Brian J Smith, Wenqing Sun, Dongxu Wang
Purpose: To quantify the reduction of relative displacement between the implanted intracavitary applicator and the patient bony anatomy, due to the use of a hover transport system during the patient transports between the imaging table and the treatment table. Material and methods: The displacement of the applicator inside the patient was measured by comparing the distance between the tip of the tandem and the pubic bone on X-ray radiography images taken before and after moving a patient to magnetic resonance/computed tomography imaging...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619059/a-comparative-assessment-of-inhomogeneity-and-finite-patient-dimension-effects-in-60-co-and-192-ir-high-dose-rate-brachytherapy
#15
Irina Fotina, Kyveli Zourari, Vasileios Lahanas, Evaggelos Pantelis, Panagiotis Papagiannis
Purpose: To perform a comparative study of heterogeneities and finite patient dimension effects in 60 Co and 192 Ir high-dose-rate (HDR) brachytherapy. Material and methods: Clinically equivalent plans were prepared for 19 cases (8 breast, 5 esophagus, 6 gynecologic) using the Ir2.A85-2 and the Co0.A86 HDR sources, with a TG-43 based treatment planning system (TPS). Phase space files were obtained for the two source designs using MCNP6, and validated through comparison to a single source dosimetry results in the literature...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619058/long-term-outcome-of-high-dose-rate-brachytherapy-and-perioperative-brachytherapy-in-early-mobile-tongue-cancer
#16
Mahadev Potharaju, Hemanth Raj E, Manavalan Muthukumaran, Murali Venkataraman, Bhargavi Ilangovan, Selvan Kuppusamy
Purpose: To evaluate long-term outcome of high-dose-rate brachytherapy and perioperative brachytherapy in early mobile tongue cancer. Material and methods: Seventy-three patients with clinically staged T1/T2 N0 M0 of mobile tongue cancer were studied retrospectively. Between January 2000 and September 2010, 47 patients underwent high-dose-rate brachytherapy (HDR-BT) alone and 26 patients underwent perioperative brachytherapy (PB). Endpoints were overall survival, disease-free survival, loco-regional control, and late side effects...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619057/accelerated-partial-breast-irradiation-in-a-single-18-gy-fraction-with-high-dose-rate-brachytherapy-preliminary-results
#17
Javier Anchuelo Latorre, Piedad Galdós, Lucía Alonso Buznego, Ana García Blanco, Juan Cardenal, María Ferri, Iván Díaz de Cerio, Elisabet Arrojo, Nicolás Sierrasesúmaga, Mónica González Noriega, Ana De Juan Ferré, Rosa Fabregat, Samuel Ruíz, Pedro J Prada
Purpose: To evaluate the feasibility of acute and chronic toxicity in patients suitable for accelerated partial breast irradiation (APBI) in a single 18 Gy fraction with multicatheter high-dose-rate (HDR) brachytherapy, as well as cosmetic and oncological outcomes. Material and methods: Between September 2014 and March 2016, twenty consecutive patients with low-risk invasive and ductal carcinoma in situ were treated with interstitial multicatheter HDR brachytherapy in a single 18 Gy fraction...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619056/should-molecular-subtype-be-recommended-as-one-of-the-selection-criteria-for-accelerated-partial-breast-irradiation-preliminary-results-from-an-asian-cohort
#18
Tabassum Wadasadawala, Monidipa Mondal, Siji Nojin Paul, Vani Parmar, Nita Nair, Tanuja Shet, Sangeeta Desai, Sudeep Gupta, Rajiv Sarin
Purpose: The purpose of this study was to report clinical outcomes in patients treated with accelerated partial breast irradiation (APBI), stratified as per molecular subtype and American Society for Therapeutic Radiology and Oncology/Groupe Européen de Curiethérapie and European Society for Radiotherapy & Oncology (ASTRO/GEC-ESTRO) patient selection criteria in order to determine whether molecular subtype should be recommended as one of the selection criteria for APBI. Material and methods: 157 early-stage breast cancers patients, treated with APBI using multi-catheter interstitial brachytherapy with ≥ 6 months follow-up were included...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619055/late-g2-vagina-toxicity-in-post-operative-endometrial-carcinoma-is-associated-with-a-68-gy-dose-equivalent-to-2-gy-per-fraction-%C3%AE-%C3%AE-3gy-at-2-cm-3-of-vagina
#19
María Del Valle Aguilera, Ángeles Rovirosa, Carlos Ascaso, Antonio Herreros, Joan Sánchez, Julia Garcia-Migue, Stephanía Cortes, Eduardo Agusti, Cristina Camacho, Yaowen Zhang, Yan Li, Sebastià Sabater, Aureli Torne, Meritxell Arenas
Purpose: To evaluate if the dose equivalent to 2 Gy per fraction (EQD2)(α/β=3Gy) at 0.1 cm3 , 1 cm3 , and 2 cm3 of vagina in vaginal-cuff-brachytherapy (VBT) (high-dose-rate [HDR] 192 Ir-source) ± external-beam-irradiation (EBRT) is associated with toxicity in post-operative endometrial carcinoma (P-EC). Material and methods: From June 2014 till November 2015, 67 consecutive P-EC patients underwent VBT ± EBRT; 44 patients received EBRT (median, 45 Gy; range, 44-50...
February 2018: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29619054/clinical-analysis-of-speculum-based-vaginal-packing-for-high-dose-rate-intracavitary-tandem-and-ovoid-brachytherapy-in-cervical-cancer
#20
Shivani Sud, Toni Roth, Ellen Jones
Purpose: Intra-vaginal packing is used to fix the applicator and displace organs at risk (OAR) during high-dose-rate intracavitary tandem and ovoid brachytherapy (HDR-ICB). We retain the speculum from applicator placement as a dual-function bladder and rectum retractor during treatment. Our objective is to review salient techniques for OAR displacement, share our packing technique, and determine the reduction in dose to OAR and inter-fraction variability of dose to OAR, associated with speculum-based vaginal packing (SBVP) in comparison to conventional gauze packing during HDR-ICB...
February 2018: Journal of Contemporary Brachytherapy
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