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Journal of Diabetes

Tomoyuki Kawada
No abstract text is available yet for this article.
January 18, 2017: Journal of Diabetes
Mingli Hao, Lin Ding, Liping Xuan, Tiange Wang, Mian Li, Zhiyun Zhao, Jieli Lu, Yu Xu, Yuhong Chen, Weiqing Wang, Yufang Bi, Min Xu, Guang Ning
BACKGROUND: Previous studies have associated bisphenol A (BPA) exposure with diabetes and related metabolic disorders such as obesity. Study regarding association of urinary BPA concentrations with central obesity risk is limited. We aimed to prospectively investigate the association of urinary BPA with incident central obesity in a Chinese population aged 40 years and above. METHODS: 888 participants who were not central obese at baseline in 2009 were followed for 4 years in Shanghai, China...
January 18, 2017: Journal of Diabetes
Yu Yi-Hao
Body weight is neither stationary nor changing unidirectionally. It usually oscillates up and down around a set-point. Two types of forces determine the direction of weight changes. Forces that push body weight away from the set-point are defined as non-homeostatic and are governed by multiple mechanisms, including but not limited to hedonic regulation of food intake. Forces that restore the set-point weight are defined as homeostatic, and they operate through the mechanisms that regulate short-term energy balance driven by hunger and satiation and long-term energy balance driven by changes in adiposity...
January 17, 2017: Journal of Diabetes
Diana Sherifali Rn
Diabetes coaching is emerging as an important role in self-management and care. Despite the rapid rise of interest in this role, the conceptualization of coaching, and how to implement and evaluate coaching has not been articulated in the literature. The objective of this review was to synthesize the diabetes coaching literature to: a) identify the components of coaching using a validated framework, including the description of the role of technology used to facilitate coaching; b) describe the implementation and evaluation measures for diabetes coaching; and c) based on the evidence, to propose a diabetes coaching model for future implementation...
January 13, 2017: Journal of Diabetes
Junmei Yin, Andrea Luk, Rebecca Wong, Harriet Chung, Alice Kong, Risa Ozaki, Ronald Ma, Chun-Chung Chow, Wingyee So, Juliana Chan
BACKGROUND: To examine the effects of mailing regular personalized follow-up(FU) reports on metabolic control and hospitalization in patients managed by the Joint Asia Diabetes Evaluation(JADE) Program. METHODS: In 2013, 1200 Chinese patients with diabetes (95.8% type 2 diabetes, mean age:58.3 ± 12.6 years, disease duration:10.1 ± 8.2 years, HbA1c: 7.4 ± 1.4%, 35% insulin-treated) underwent comprehensive assessment(CA) with usual clinic FU visits...
January 12, 2017: Journal of Diabetes
Zachary T Bloomgarden
No abstract text is available yet for this article.
January 11, 2017: Journal of Diabetes
Payal H Marathe, Helen X Gao, Kelly L Close
No abstract text is available yet for this article.
January 10, 2017: Journal of Diabetes
Du Rui, Cheng Di, Lin Lin, Sun Jichao, Peng Kui, Xu Yu, Xu Min, Chen Yuhong, Bi Yufang, Wang Weiqing, Lu Jieli, Ning Guang
BACKGROUND: Rising evidence suggested that serum carbohydrate antigen (CA) 19-9 was associated with abnormal glucose metabolism. However, data on the association between CA 19-9 and metabolic syndrome is limited. In the current study, we aimed to investigate the association between serum CA 19-9 and metabolic syndrome. METHODS: A cross-sectional study was conducted among 3641 participants aged 40 years or older from the Songnan community, Baoshan district in Shanghai...
January 9, 2017: Journal of Diabetes
Zhang Lu, Wang Jinjin, Zhang Ming, Wang Guo'an, Shen Yanxia, Wu Dongting, Wang Chongjian, Li Linlin, Ren Yongcheng, Wang Bingyuan, Zhang Hongyan, Yang Xiangyu, Zhao Yang, Han Chengyi, Zhou Junmei, Pang Chao, Yin Lei, Zhao Jingzhi, Luo Xinping, Hu Dongsheng
BACKGROUND: Low-density lipoprotein receptor-related protein 5 (LRP5) plays an important role in glucose and cholesterol metabolism, so a cohort study was used to evaluate the association of LRP5 variants and incidence of type 2 diabetes mellitus (T2DM) in a rural adult Chinese population. METHODS: A total of 7751 subjects ≥18 years old and without T2DM underwent genotyping at baseline; 6326 subjects (81.62%) were followed-up, with 5511 eligible for this analysis...
January 9, 2017: Journal of Diabetes
Yi Shi, Paul M Vanhoutte
Endothelial cells, as well as their major products nitric oxide and prostacyclin, play a key role in the regulation of vascular homeostasis. Diabetes mellitus is an important risk factor for cardiovascular disease. Diabetes-induced endothelial dysfunction is a critical and initiating factor in the genesis of diabetic vascular complications. The present review focuses on both large blood vessels and the microvasculature. The endothelial dysfunction in diabetic macrovascular complications is characterized by a reduced nitric oxide bioavailability, poorly compensated for by increased production of prostacyclin and/or endothelium-dependent hyperpolarizations, and increased production /action of endothelium-derived vasoconstrictors...
January 3, 2017: Journal of Diabetes
Agustín Ramos-Prol, David Hervás-Marín, Alia GarcÍa-Castell, Juan Francisco Merino-Torres
BACKGROUND: There is discrepancy between the results of different studies about the impact of diabetes mellitus on morbidity and mortality in patients undergoing liver transplantation. The objective of the study was to compare mortality, risk of liver graft rejection and cardiovascular events in patients with and without diabetes undergoing liver transplantation, with a follow-up of 10 years. METHODS: Retrospective study of 183 patients transplanted during the years 2005 and 2006...
December 31, 2016: Journal of Diabetes
Naglaa Khedr
BACKGROUND: Uncontrolled diabetes mellitus (DM) results in neuronal damage caused by increased intracellular glucose. The addition of natural products as complementary therapy can reduce neuronal complications. The main objectives of this study was to determine whether fish oil (FO) and wheat germ oil (WGO) supplementation protect rat brains in streptozotocin (STZ)-induced diabetic rats via estimating lipid peroxidation, inflammatory and anti-oxidant status of brain. METHODS: Diabetes was induced in male Wistar rats by single i...
December 29, 2016: Journal of Diabetes
Roberta Bgeginski, Paula A B Ribeiro, Michelle F Mottola, José Geraldo L Ramos
BACKGROUND: Exercise is an important part of gestational diabetes mellitus (GDM) lifestyle management. However, there is no meta-analysis analyzing the effects of exercise programs on fasting blood glucose (FBG) in women with GDM. A systematic review with meta-analysis was performed to evaluate the effect of weekly-supervised exercise (EXE group) or physical activity counseling (PA group) in women with GDM compared to usual prenatal (UPN group) on glycemic control. METHODS: Eligible trials were identified from MEDLINE, EMBASE, Web of Science, Scopus and SportDiscus up to 11 December 2016...
December 29, 2016: Journal of Diabetes
Simin Liu, Qi Sun
In assessing clinical and pathophysiological development of type 2 diabetes (T2D), the critical role of the sex steroids axis is underappreciated particularly concerning the sex specific relations with many relevant cardiometabolic outcomes. In this issue of the Journal, we provide a comprehensive overview of these strong associations of germline variants in the genes governing the sex-steroids pathways, plasma levels of steroid-hormones, and sex hormone-binding globulin (SHBG) with T2D risk that have been observed in many clinical as well as high-quality large prospective cohorts of men and women across ethnic populations...
December 19, 2016: Journal of Diabetes
Wing Bun Chan, Andrea Luk, Wing Sun Chow, Vincent Tok Fai Yeung
There is increasing evidence that the pathophyisology of type 2 diabetes mellitus (T2DM) in Asian patients differs from that seen in western patients, with early phase insulin deficiencies, increased postprandial glucose excursions, and increased sensitivity to insulin. Asian patients may also experience higher rates of gastrointestinal adverse events associated with glucagon-like peptide-1 receptor agonists (GLP-1 RAs), such as nausea and vomiting, compared with their western counterparts. These factors should be taken into consideration when selecting therapy for basal insulin treatment intensification in Asian patients...
December 15, 2016: Journal of Diabetes
Hsin-Fang Chung, Abdullah Al Mamun, Meng-Chuan Huang, Kurt Z Long, Ya-Fang Huang, Shyi-Jang Shin, Shang-Jyh Hwang, Chih-Cheng Hsu
BACKGROUND: We investigated obesity and weight change in relation to risk of chronic kidney disease (CKD) in Asian patients with Type 2 diabetes using longitudinal data. METHODS: We recruited 1187 diabetic patients aged 30-70 years at baseline (2003-2005), and follow-up surveys were completed in 2008, 2009, and 2010. CKD was defined as having an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m(2) ; body mass index (BMI; kg/m(2) ) was categorised as normal (18...
December 15, 2016: Journal of Diabetes
Mingming Liu, Xiaoyan Zhang, Ailing Li, Xu Zhang, Bing Wang, Bingwei Li, Shuying Liu, Hongwei Li, Ruijuan Xiu
BACKGROUND: Microcirculation plays an important role in the pathogenesis of diabetes and its complications. We hypothesize that pancreatic-islet microvascular vasomotion as a parameter of functional status of pancreatic-islet microcirculation is abnormal in diabetic mice and insulin treatment might restore that dysfunction. METHODS: Mice were divided into non-diabetic control, untreated diabetic and diabetic treated with insulingroups (n = 6 in each group) randomly...
December 15, 2016: Journal of Diabetes
Mohammad Badavi, Amir Bazaz, Mahin Dianat, Alireza Sarkaki
BACKGROUND: One of the many complications that caused by diabetes mellitus is endothelial dysfunction. This study was designed to evaluate the effects of gallic acid on the mesenteric vascular bed (MVB) response to histamine in diabetic rats. METHODS: Forty male Wistar rats were randomly assigned into five groups: Control (C), alloxan-induced diabetic (D), and three separate diabetic groups treated with different doses of gallic acid. Six weeks after diabetes induction by alloxan and treatment with gallic acid, the total antioxidant capacity (TAC), malondialdehyde (MDA) and histamine vasodilatory response of MVB was measured as changes in perfusion pressure...
December 10, 2016: Journal of Diabetes
Serena Low, Su Chi Lim, Lee Ying Yeoh, Yan Lun Liu, Jian Jun Liu, Sharon Fun, Chang Su, Xiao Zhang, Tavintharan Subramaniam, Chee Fang Sum
BACKGROUND: We examined the association between HbA1c variability and renal disease progression based on estimated glomerular filtration rate (eGFR) decline in patients with type 2 diabetes mellitus (T2DM) in Singapore. METHODS: We retrospectively assessed the glycemic burden and renal function in 1628 patients in 2002-2014. Multivariable logistic regression was used to assess the relationships between HbA1c variability expressed as HbA1c coefficient of variation (HbA1c-CV) in quartiles, HbA1c-intrapersonal mean and eGFR decline, adjusted for baseline covariates...
December 9, 2016: Journal of Diabetes
Zachary Bloomgarden, Guang Ning
No abstract text is available yet for this article.
December 1, 2016: Journal of Diabetes
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