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Journal of Diabetes

Liang Sun, Huaixing Li, Xu Lin
Due to rapid nutrition transitions, cardiometabolic diseases such as metabolic syndrome, type 2 diabetes, and cardiovascular diseases have been increasing at an alarming rate in the Chinese population. Moreover, Asians including Chinese have been hypothesized to have higher susceptibility for cardiometabolic diseases than Caucasians. Early prediction and prevention are the keys to controlling this epidemic trend, for which identification of novel biomarkers is critical to reflect environmental exposure, as well as to reveal endogenous metabolism and pathophysiology mechanisms...
September 21, 2018: Journal of Diabetes
Yicheng K Bao, Lamont G Weide, Vishwanath C Ganesan, Ishaan Jakhar, Janet B McGill, Suman Sahil, An-Lin Cheng, Monica Gaddis, Betty M Drees
BACKGROUND: Patients with type 1 diabetes are at risk for other autoimmune diseases (ie. polyautoimmunity). The prevalence and risk factors of this phenomenon has been under-reported in adults and ethnic minorities, and data is lacking about non-endocrine autoimmune diseases. METHODS: Study population data was gathered from the HealthFacts, a de-identified patient database from electronic medical records systems in the United States. Patients with an International Classification of Diseases diagnosis code specifying type 1 diabetes were included, and patients with a diagnosis of type 2 diabetes mellitus were excluded...
September 18, 2018: Journal of Diabetes
Minoru Tanaka, Takeshi Morifuji, Madoka Yoshikawa, Ryosuke Nakanishi, Hidemi Fujino
BACKGROUND: Diabetes mellitus resulted in a decrease of muscle mass and harmful complications. Blood flow restriction (Bfr) and electrical stimulation (ES) increase muscle protein synthesis. We hypothesized that the combined treatment Bfr and low intensity ES might be more effective in preventing diabetes-associated muscle atrophy via the inhibition of down-regulated protein synthesis related pathways. The present study sought to evaluate the effects of combined treatment with Bfr and low intensity ES on diabetes-associated muscle atrophy through advanced glycation end products (AGEs)/receptor for AGEs (RAGE) in rats...
September 18, 2018: Journal of Diabetes
Martin J Kurian, Peter J Rentzepis, Ann M Carracher, Kelly L Close
No abstract text is available yet for this article.
September 16, 2018: Journal of Diabetes
Zachary T Bloomgarden
No abstract is available for this article. This article is protected by copyright. All rights reserved.
September 11, 2018: Journal of Diabetes
Jing Liang, Chaoyang Lv, Minling Chen, Ming Xu, Chenhe Zhao, Yinqiu Yang, Jina Wang, Dong Zhu, Jian Gao, Ruiming Rong, Tongyu Zhu, Mingxiang Yu
BACKGROUND: The effects of preoperative hepatitis B virus (HBV) infection, hepatitis C virus (HCV) infection, and co-infection with both viruses on the development of new-onset diabetes after transplantation (NODAT) remain unexplored and controversial in kidney transplant recipients (KTRs). We aimed to examine the associations between different preoperative viral statuses, including HBV infection, HCV infection, as well as co-infection and incident NODAT in a large population of Chinese KTRs...
September 11, 2018: Journal of Diabetes
Junichi Okada, Eijiro Yamada, Yawara Niijima, Shuichi Okada, Masanobu Yamada
No abstract text is available yet for this article.
September 7, 2018: Journal of Diabetes
Nafeesa N Dhalwani, Francesco Zaccardi, Hina Waheed, Jemma Mytton, Dimitris Papamargaritis, David R Webb, Felicity Evison, Richard Lilford, Melanie J Davies, Kamlesh Khunti
BACKGROUND: Bariatric surgery reduces cardiovascular events and mortality risk in obese individuals. However, it is unclear whether diabetes modified this effect. We aimed to examine mortality, cardiovascular and cancer risk following bariatric surgery in adults with and without pre-existing diabetes and compare mortality risk to the general population. METHODS: Using mortality linked-Hospital Episodes Statistics (2006-2014) from England, we examined risk of death, myocardial infarction, stroke, unstable angina, heart failure, and cancer following bariatric surgery; and compared risk of death in people undergoing bariatric to mortality rates of the general population...
September 7, 2018: Journal of Diabetes
Yan Li, Yunyi Gao, Yun Gao, Dawei Chen, Chun Wang, Guanjian Liu, Xin Yang, Xingwu Ran
BACKGROUND: Recent years, many studies have reported that autologous platelet-rich gel (APG) is an effective adjunctive method to promote chronic cutaneous ulcers in diabetics. The aim of the present study was to explore the efficacy and safety of APG for the topical treatment of diabetic chronic cutaneous ulcers. METHODS: The Chinese CBM, CNKI, VIP, Wanfang databases, Cochrane Library databases, EBSCOhost, Embase and PubMed on October 18, 2017 were systematically searched...
September 5, 2018: Journal of Diabetes
Xiaoyu Xiao, Lili Liu, Yang Xiao, Zhiguo Xie, Long Li, Houde Zhou, Weili Tang, Shiping Liu, Zhiguang Zhou
No abstract text is available yet for this article.
September 5, 2018: Journal of Diabetes
Mei Chung Moh, Chee Fang Sum, Tavintharan Subramaniam, Keven Ang, Pek Yee Kwan, Simon Biing Ming Lee, Wern Ee Tang, Su Chi Lim
BACKGROUND: The association between gain in adiposity and renal decline in a large prospective multi-ethnic South-East Asian cohort with type 2 diabetes mellitus (T2DM) was evaluated. METHODS: T2DM participants (N=2,057) were recalled for re-assessment 3 years after baseline visit. The final cohort comprising 1,014 subjects was categorized into tertiles based on changes in body weight (ΔWt), body mass index (ΔBMI), visceral fat area (ΔVFA), and BMI-adjusted VFA (ΔVFABMI )...
September 3, 2018: Journal of Diabetes
Robert A Vigersky
Hemoglobin A1C (HbA1C), the gold standard for monitoring overall glycemia. However, HbA1C has several important limitations giving more weight to the prior 2-3 months rather than short-term glycemic control. In addition, the level of the HbA1C does not reflect the important interpersonal differences in its relationship with mean glucose. In addition, HbA1C is affected by many common clinical conditions (anemia, uremia) that can interfere with the accuracy of its measurement in the laboratory. The development and refinement of CGM, a glucose- and patient-centric technology, over the past two decades has permitted the creation of new single and composite metrics, e...
August 26, 2018: Journal of Diabetes
Chandra K Bhattacharjee, Suman K Paine, Jagadish Mahanta, Sawjib Borphukan, Prasanta K Borah
No abstract text is available yet for this article.
August 26, 2018: Journal of Diabetes
Sarah Cuschieri, Josanne Vassallo, Neville Calleja, Julian Mamo
No abstract text is available yet for this article.
August 25, 2018: Journal of Diabetes
Anoop Misra, Zachary T Bloomgarden
No abstract text is available yet for this article.
August 20, 2018: Journal of Diabetes
Peter J Rentzepis, Martin J Kurian, Ann M Carracher, Kelly L Close
No abstract is available for this article. This article is protected by copyright. All rights reserved.
August 18, 2018: Journal of Diabetes
Zhaosheng Tang, Fuming Cao, Hao Zhang, Jing Tang, Huizhi Li, Yiyun Zhang, Bo Feng, Hua Wang
BACKGROUND: Insulin-like growth factor-1 (IGF-1) is a multidimensional neurotrophic factor. Nevertheless, it has been reported that IGF-1 may lead to hyperalgesia. This study aimed to investigate the effects of IGF-1 on the overall behaviour of diabetic mice and to explore the possible mechanisms of IGF-1-induced pain effects. METHODS: The mice were divided into five groups: db/m group, db/db group, db/db+vehicle group, IGF-1-treated db/db group and IGF-1-JB-1-treated db/db group...
August 13, 2018: Journal of Diabetes
Michel Hermans, Sylvie Ahn, Michel Rousseau
BACKGROUND: To establish the isolated and crossed impacts of familial histories (FH) of early-onset coronary heart disease (EOCHD) and type 2 diabetes mellitus (T2DM) on their diabetic offsprings. METHODS: The cardiometabolic phenotype of 1098 T2DM patients was analysed according to FHs of DM and/or EOCHD, including body composition, fasting insulinemia, insulin sensitivity, β-cell function (BCF), lipids, lipoprotein(a), high-density lipoprotein (HDL) number/functionality, and micro-/macrovascular complications...
August 13, 2018: Journal of Diabetes
Kalina Rajaobelina, Courtney Dow, Francesca Romana Mancini, Laureen Dartois, Marie-Christine Boutron-Ruault, Beverley Balkau, Fabrice Bonnet, Guy Fagherazzi
BACKGROUND: Though many type 2 diabetes (T2D) risk factors have been identified, little is known on their contributions to the diabetes burden at the population level. METHODS: The study included, 72 655 French women from the E3N prospective cohort followed between 1993 and 2011. We used Cox multivariable models including the main T2D risk factors (metabolic, dietary, clinical, socio-economic and hormonal), as well as a healthy lifestyle index combining five characteristics (smoking, body mass index (BMI), alcohol consumption, fruit and vegetable consumption and physical activity) to estimate hazard ratios and population attributable fractions (PAFs) for T2D...
August 11, 2018: Journal of Diabetes
Jun Yang Lee, Christina San San Tan, Shaun Wen Huey Lee
No abstract text is available yet for this article.
August 10, 2018: Journal of Diabetes
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