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Orthopaedic Surgery

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https://www.readbyqxmd.com/read/28447380/lncrna-h19-modulates-wnt-%C3%AE-catenin-signaling-by-targeting-dkk4-in-hindlimb-unloaded-rat
#1
Bing Li, Jun Liu, Jie Zhao, Jian-Xiong Ma, Hao-Bo Jia, Yang Zhang, Guo-Sheng Xing, Xin-Long Ma
OBJECTIVE: To investigate the biological functions of long noncoding RNA-H19 (H19) in the pathogenesis of disuse osteoporosis (DOP). METHODS: Fifty-four male Sprague Dawley (SD) rats were randomly divided into three groups: baseline control (BC, 6), age-matched control (AC, 24), and hindlimb unloading (HLU, 24). The rats in the BC group were sacrificed at the beginning of the experiment, while the AC and HLU rats were sacrificed at different times (7, 14, 21 and 28 days after HLU)...
April 26, 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28371503/effect-of-femoral-component-flexion-implantation-on-the-mediolateral-bone-prosthetic-fit-in-total-knee-arthroplasty
#2
Shi-Chang Chen, Yi-Ming Zeng, Meng-Ning Yan, Bing Yue, Jun Zhang, You Wang
OBJECTIVE: Femoral component overhang in total knee arthroplasty (TKA) has been reported in previous studies. The purpose of this study was to evaluate the effect of femoral component flexion implantation on mediolateral bone-prosthetic fit in TKA. METHODS: Virtual prosthesis implantations were performed on computed tomographic models of 10 Chinese knees with femoral prostheses of the Advance Medial-Pivot knee system (MicroPort Orthopedics, Arlington, TN, USA), with the femoral component positioned at 0°, 3°, or 6° of flexion in the sagittal plane...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28371502/comparison-of-posteromedial-versus-posterolateral-approach-for-posterior-malleolus-fixation-in-trimalleolar-ankle-fractures
#3
Sheng Zhong, Lin Shen, Jia-Guo Zhao, Jie Chen, Jin-Feng Xie, Qi Shi, Ying-Hua Wu, Xian-Tie Zeng
OBJECTIVE: To compare clinical and radiographic outcomes of posterior malleolar fractures (PMF) treated with lag screws from anterior to posterior versus posterior to anterior approach. METHODS: We retrospectively analyzed 48 patients with trimalleolar fractures who underwent open reduction and internal fixation (ORIF) with either posteromedial (PM) or posterolateral (PL) approaches between January 2012 and December 2014. Fixation of the posterior malleolus was made with anteroposterior screws in 20 patients using the PM approach and posteroanterior screws in 28 patients using the PL approach...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28371501/therapeutic-outcomes-of-kalix-ii-in-treating-juvenile-flexible-flatfoot
#4
Le Cao, Xu-Dong Miao, Yong-Ping Wu, Xiang-Feng Zhang, Qiang Zhang
OBJECTIVES: To evaluate the therapeutic outcomes with Kalix II subtalar arthroereisis in sinus tarsi for juvenile flexible flatfoot. METHODS: A retrospective analysis of the data of 20 juveniles with symptomatic flexible flatfoot (27 feet) who underwent the Kalix II implant procedure from January 2008 to September 2012 was performed. The pain during daily activities was assessed and followed up by use of a standard 10-point visual analog scale (VAS), and function was evaluated using the American Orthopaedic Foot and Ankle Society (AOFAS) ankle and hindfoot scoring system, and anteroposterior talar-first metatarsal angle, lateral talar-first metatarsal angle, calcaneal pitch angle, and talar declination angle at X-ray film were measured to assess the therapeutic outcomes...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28371500/joint-preserving-surgery-for-talar-malunions-or-nonuions
#5
Gang Chen, Mu Hu, Yang Xu, Yue-Huan Zhen, Yuan Hong, Xiang-Yang Xu
OBJECTIVE: To describe the technique and analyze the outcomes of joint-preserving surgical treatments which included anatomical reconstruction or alignment correction for talar malunions or nonunions, and avoid development of degenerative changes in the adjacent joints. METHODS: Eight patients who had painful talar malunions or nonunions treated between 2009 and 2015 were included in this retrospective study. The mean age of the patients was 35.6 years, with patients aged from 18 to 58 years...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28371499/rod-migration-to-the-thoracic-subarachnoid-space-after-c1-2-instrumentation-a-case-report-and-literature-review
#6
Seref Dogan, Elif Basaran Gundogdu, Mevlüt Özgür Taşkapılıoğlu, Ahmet Karaoglu
Posterior instrumented fusion of the cervical spine is a common surgical procedure in the treatment of cervical subluxation, fractures, and stenosis. Although malpositions are commonly seen, it is rare to observe the malposition of the rod or interconnection because of hardware failure. A 62-year-old woman with spastic tetraparesis as a sequel to pediatric meningitis with C1 -C2 cervical subluxation and myelomalacia had undergone laminectomy of C1 and C1 lateral mass and C2 bilateral pedicular screw fixation...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28371498/chinese-guideline-for-the-diagnosis-and-treatment-of-osteonecrosis-of-the-femoral-head-in-adults
#7
(no author information available yet)
The treatment of adult osteonecrosis of the femoral head (ONFH), with 8.12 million patients in China, remains a challenge to surgeons. To standardize and improve the efficacy of the treatment of ONFH, Chinese specialists updated the experts' suggestions in March 2015, and an experts' consensus was given to provide a current basis for the diagnosis, treatment and evaluation of ONFH. The current guideline provides recommendations for ONFH with respect to epidemiology, etiology, diagnostic criteria, differential diagnosis, staging, treatment, as well as rehabilitation...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28371497/staged-management-of-missed-lisfranc-injuries-a-report-of-short-term-results
#8
Pin Feng, Ya-Xing Li, Jia Li, Xiang-Yu Ouyang, Wei Deng, Yu Chen, Hui Zhang
OBJECTIVE: Lisfranc joint injury is a rare injury and can be easily missed at the initial treatment. Once ignored, late reduction is very difficult and requires extensive dissection. Surgical outcome is not as good as in the case of an early reduction. The aim of this cohort study was to analyze the midterm clinical and radiographic outcomes of staged reduction and fixation in a consecutive series of patients with old Lisfranc injuries. METHODS: Fifteen patients (16 feet) with missed Lisfranc injuries were treated with staged reduction...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28371496/osteogenic-ability-detection-of-human-bone-morphogenetic-protein-2-gene-activated-nano-bone-putty-by-reusable-double-cavity-bone-harvest-chamber
#9
Li Sun, Zhi-Hui Yan, Xian-Teng Yang, Tai-Zhe Wang, Qin Yang, Sen-Lei Li, Ying-Jie Nie, Xiao-Bin Tian
OBJECTIVE: To explore the feasibility of implanting a self-designed reusable double-cavity bone harvest chamber into Guizhou mini-pigs for observation of the osteogenic effect of human bone morphogenetic protein-2 (hBMP-2) gene-activated nano bone putty on bone in growth. METHODS: Eight healthy 12-month-old female Guizhou mini-pigs were used for the present experiment. In the first operation, empty double-cavity bone harvest chambers (n = 8) were implanted into the femoral metaphysis of the animals as a blank control group...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28371495/safe-zone-of-posterior-screw-insertion-for-talar-neck-fractures-on-3-dimensional-reconstruction-model
#10
Jian-Qun Wu, Sheng-Hui Ma, Song Liu, Cheng-He Qin, Dan Jin, Bin Yu
OBJECTIVE: To investigate the optimal posterior screw placement and the geometry of safe zones for screw insertion in the talar neck. METHODS: Computed tomography data for 15 normal feet were imported into Mimics 10.01 software for 3-dimensional reconstruction; 4.0-mm-diameter screws were simulated from the lateral tubercle of the posterior process of the talus to the talar head. The range of screw paths trajectories and screw lengths at nine locations that did not breach the cortex of the talus were evaluated...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28300359/influence-of-different-boundary-conditions-in-finite-element-analysis-on-pelvic-biomechanical-load-transmission
#11
Pan Hu, Tao Wu, Hui-Zhi Wang, Xin-Zheng Qi, Jie Yao, Xiao-Dong Cheng, Wei Chen, Ying-Ze Zhang
OBJECTIVE: To observe the effects of boundary conditions and connect conditions on biomechanics predictions in finite element (FE) pelvic models. METHODS: Three FE pelvic models were constructed to analyze the effect of boundary conditions and connect conditions in the hip joint: an intact pelvic model assumed contact of the hip joint on both sides (Model I); and a pelvic model assumed the hip joint connecting surfaces fused together with (Model II) or without proximal femurs (Model III)...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28300344/intramedullary-nailing-combined-with-bone-grafting-for-benign-lesions-of-the-proximal-femur
#12
Yan Zhang, Jia-Zhen Li, Xin-Chang Lu, Yi Zhang, Huai-Shuan Zhang, Hai-Long Shi, Zheng Lei, Guang Feng, Wei-Ping Fu
OBJECTIVE: To evaluate the effectiveness of intramedullary nailing for benign lesions of the proximal femur. METHOD: A retrospective analysis was carried out on 68 cases of benign lesions in the proximal femur at our hospital from April 2002 to April 2013 (38 men and 30 women). Mean age at surgery was 35.5 years (range, 22-56 years). The cases were divided into two groups: curettage of the lesion with bone grafting only as the grafting group (32 cases) and internal fixation after removal of the lesion as the fixation group (36 cases)...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28296225/treatment-of-medial-malleolus-or-pure-deltoid-ligament-injury-in-patients-with-supination-external-rotation-type-iv-ankle-fractures
#13
Xu Wang, Chao Zhang, Jian-Wen Yin, Chen Wang, Jia-Zhang Huang, Xin Ma, Cheng-Wei Wang, Xue Wang
OBJECTIVE: To investigate the effect of internal fixation on postoperative ankle function in patients with supination-external rotation type IV ankle fractures, including medial malleolus fractures and deltoid ligament injury. METHODS: Between January 2012 and June 2014, patients with medial structure injuries were enrolled in this study and assigned to the medial malleolus fracture group or the deltoid ligament group. The surgical procedures for the two groups were documented...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28294528/effect-of-intraoperative-dexamethasone-on-pain-scores-and-narcotic-consumption-in-patients-undergoing-total-knee-arthroplasty
#14
Jason Samona, Carrie Cook, Kyle Krupa, Krystle Swatsell, Andrew Jackson, Chase Dukes, Sidney Martin
OBJECTIVE: To examine whether the addition of intravenous dexamethasone during total knee arthroplasty (TKA) would be effective at reducing postoperative pain scores and postoperative opioid consumption. METHODS: A total of 102 patients undergoing TKA were placed into two groups: 55 subjects received intraoperative dexamethasone 8 mg intravenously (treatment group) and 47 did not receive dexamethasone at any time during the perioperative period. Comparison was made using the 0-10 numeric pain rating scale and the amount of opioids used in each group...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28276661/anterior-lumbar-interbody-fusion-in-left-sided-inferior-vena-cava-and-right-sided-aortic-arch
#15
Kevin Phan, Bernard A M Fang, Monish M Maharaj, Andrew F Lennox, Ralph J Mobbs
Spinal fusion via anterior lumbar interbody fusion (ALIF) can offer symptomatic relief to patients that suffer severe low back pain, radiculopathy, and claudication. However, a detailed working knowledge of the thoracic, abdominal, and lumbar anatomy, particularly of the vasculature, is vital. We report the case of a 68-year-old man who presented with radiculopathy and progressively worsening low back pain despite 9 months of unsuccessful conservative therapy and pain management. Preoperative computed tomography and magnetic resonance imaging revealed a rare anatomical variation, with an anomalous left-sided inferior vena cava and anomalous aorta...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28276651/realignment-surgery-for-malunited-ankle-fracture
#16
Chang-Jun Guo, Xing-Cheng Li, Mu Hu, Yang Xu, Xiang-Yang Xu
OBJECTIVE: To investigate the characteristics and the results of realignment surgery for the treatment of malunited ankle fracture. METHODS: Thirty-three patients with malunited fractures of the ankle who underwent reconstructive surgery at our hospital from January 2010 to January 2014 were reviewed. The tibial anterior surface angle (TAS), the tibiotalar tilt angle (TTA), the malleolar angle (MA), and the tibial lateral surface angle (TLS) were measured. Clinical assessment was performed with use of the American Orthopaedic Foot and Ankle Society (AOFAS) scale and visual analogue scale (VAS) scores, and the osteoarthritis stage was determined radiographically with the modified Takakura classification system...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28276650/comparison-of-arthrodesis-and-non-fusion-to-treat-lisfranc-injuries
#17
Yu-Sen Qiao, Jun-Kun Li, Hao Shen, Hai-Yan Bao, Ming Jiang, Yan Liu, Wasim Kapadia, Hong-Tao Zhang, Hui-Lin Yang
OBJECTIVE: "Lisfranc joint injury" is comprised of a tarsometatarsal joint-complex injury. The Lisfranc complex injury is always a challenge for orthopedists, and the optimum treatment is still up for debate. Anatomic reduction and stable internal fixation prove to have no satisfactory outcomes. This research aims to compare the clinical curative effects, complications and radiographic features of arthrodesis and non-fusion of the Lisfranc joint in the follow-up of the patients who suffered Lisfranc injuries...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28276647/clinical-comparison-of-extensile-lateral-approach-and-sinus-tarsi-approach-combined-with-medial-distraction-technique-for-intra-articular-calcaneal-fractures
#18
Hai-Chao Zhou, Tao Yu, Hao-Yang Ren, Bing Li, Kai Chen, You-Guang Zhao, Yun-Feng Yang
OBJECTIVE: To study and compare the clinical outcomes of open reduction and internal fixation via extensile L-shape incision and limited open reduction via the sinus tarsi approach using the medial distraction technique for intra-articular calcaneal fractures. METHODS: We performed a retrospective review of 65 intra-articular calcaneal fractures treated operatively between March 2012 and February 2015. Patients were divided into two groups: 28 were in the sinus tarsi approach group and 37 were in the extensile lateral approach group...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28276642/role-of-clavicle-chest-cage-angle-difference-in-predicting-postoperative-shoulder-balance-in-lenke-5c-adolescent-idiopathic-scoliosis-patients-after-selective-posterior-fusion
#19
Zhen Liu, Zong-Shan Hu, Yong Qiu, Zhen Zhang, Zhi-Hui Zhao, Xiao Han, Ze-Zhang Zhu
OBJECTIVE: To evaluate the role of preoperative clavicle chest cage angle difference (CCAD) on postoperative radiographic shoulder imbalance, patient's satisfaction and surgeon's fulfillment in Lenke 5 adolescent idiopathic scoliosis (AIS). CCAD, as a novel radiographic parameter, has proven to be a reliable predictor for postoperative shoulder imbalance in Lenke 1 AIS patients. However, the value of CCAD in predicting shoulder balance has never been evaluated in Lenke 5 AIS patients...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28276640/prospective-review-of-mesenchymal-stem-cells-differentiation-into-osteoblasts
#20
REVIEW
Priyanka Garg, Matthew M Mazur, Amy C Buck, Meghan E Wandtke, Jiayong Liu, Nabil A Ebraheim
Stem cell research has been a popular topic in the past few decades. This review aims to discuss factors that help regulate, induce, and enhance mesenchymal stem cell (MSC) differentiation into osteoblasts for bone regeneration. The factors analyzed include bone morphogenic protein (BMP), transforming growth factor β (TGF-β), stromal cell-derived factor 1 (SDF-1), insulin-like growth factor type 1 (IGF-1), histone demethylase JMJD3, cyclin dependent kinase 1 (CDK1), fucoidan, Runx2 transcription factor, and TAZ transcriptional coactivator...
February 2017: Orthopaedic Surgery
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