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Gulf Journal of Oncology

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https://www.readbyqxmd.com/read/29607829/fatal-outcome-of-recurrent-infantile-pelvic-desmoid-tumor-treated-with-tamoxifene
#1
Lamiae Amaadour, Zineb Benbrahim, Othmane Zouiten, Nezar Bourdi, Youssef Lamrani Alaoui, Asmae El Mazti, Nawal Hammas, Nawfel Mellas
Desmoid tumors are rare benign neoplasms with an aggressive local growth. In children, intra-abdominal localization is less frequent and few reports exist in the literature about the management of DTs in those special patients. In our report, we describe a case of a 13-year old patient with a bifocal intra-abdominal DT, treated unsuccessfully with tamoxifene, and we discuss briefly the existing literature data.
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29607828/t-cell-large-granular-lymphocytic-leukemia-with-pulmonary-hypertension
#2
Sidra Khalid, Hamed Daw, Miriam Jacob, Megan Nakashima
T cell large granular lymphocytic leukemia is a hematological disorder which is characterized by the proliferation of CD 3+ cytotoxic T cells. We present a case about a patient who was diagnosed with T cell large granular lymphocytic leukemia and then developed pulmonary hypertension. He was treated for his leukemia with methotrexate and simultaneously treated for his pulmonary hypertension with selexipag and ambrisentan. As his leukemia improved, we also noticed an improvement in his pulmonary hypertension from a NYHA class IV to class I...
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29607827/vaginal-metastasis-of-renal-clear-cell-cancer
#3
Rehailia-Blanchard Amel, Morel Adeline, Rancoul Chloé, He Ming Yuan, Magné Nicolas, Falkowski Sabrina
BACKGROUND: Vaginal metastases originating from renal cancer remain a rare event, with less than 100 cases reported in the literature. The spreading mechanism is still under scrutiny. The tumoral bleeding often is a symptom revealing vaginal metastases. CASE: The present work reports patient case having vaginal metastasis of renal clear-cell cancer. The vaginal metastasis was treated by a 3-D conformational radiotherapy. Our experience is discussed with respect to an updated literature review concerning the medical management of vaginal metastasis related to kidney cancer...
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29607826/tumor-recurrence-at-donor-site-of-pectoralis-major-myocutaneous-flap-with-tumor-free-primary-oral-carcinoma
#4
Rakesh Kain, Suvashis Dash
Pectoralis major myocutaneous flap is an important option for post onco reconstruction in head and neck region. Among the several complications mentioned in the literature, tumor recurrence at the donor site of flap is late and rare complication. Tumor implantation at the donor site of flap is a possible explanation. The occurrence of this type case is rare. We are reporting a case of tumor recurrences of pectoralis major myocutaneous flap donor site without presence of index tumor or detectable systemic disease...
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29607825/transanal-minimally-invasive-surgery-tamis-first-in-kuwait-a-case-report
#5
Abdullah A AlHaddad, Ali S Mouzannar, Bader Marafi, Ibtisam Albader, Mona A Khoursheed, Ali Sayed Ahmed Alsayed
Transanal Minimally Invasive Surgery (TAMIS) is a one of new platform used to help and achieve better outcome in using transanal approach for the treatment of rectal neoplasm. High definition camera and high tech equipment are used to perform this kind of surgery. The main benefit of using this approach is to provide the best outcome or the patient compared to the traditional transanal approach. This platform can be used for a variety of cases, benign and malignant tumor and for the benign condition. We report the first TAMIS perfo b rmed in the Kuwait and probably in the Middle East with 2 years of follow up...
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29607824/lymphoid-proliferation-in-eyelid-a-primary-follicular-lymphoma-case
#6
Deivy Cruzado-Sánchez, Walter Andree Tellez, Solon Serpa-Frias, Grisnery Maquera
Ocular adnexal lymphoma (OAL) constitutes 8% of all extranodal lymphomas, being rare in the eyelids (5-20%). The objective was to report a case of eyelid follicular lymphoma in a young adult woman. A 35-year-old female with swelling in left lower eyelid with development for 2 months. The visual acuity was 20/20 in both eyes, the tumor mass was 3 cm wide and 1.5 cm long. The contrast-enhanced computed tomography showed a soft-tissue injury in the left lower eyelid but had no signs of local spread according to description...
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29607823/risk-factors-of-cancer-in-the-united-arab-emirates
#7
Hira Abdul Razzak, Alya Harbi, Wael Shelpai, xAhmadxx Qawas
Cancer is recognized to be a major healthcare problem globally. Cancer is a disease that mainly occurs when alterations in a normal cell group within the body leads to uncontrolled growth, mainly causing a lump referred to as a tumor. The aim of this study is to systematically review and extract studies reporting the risk factors of cancer in UAE between 2007 and 2016. A systematic literature search was performed by using "PubMed, Scopus databases, Science direct, and local journals" and appropriate key terms to retrieve studies carried out in United Arab Emirates with regards to risk factors of the cancer...
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29607822/cancer-statistics-in-giresun-province-turkey-a-12-years-retrospective-review
#8
Aysegül Çebi, Egemen Akgün, Tuncer Öztürk, Esin Avci
AIM: The aim of this retrospective study was to analyze 6,613 diagnosed cancer cases in the Black Sea Turkish province of Giresun over a period of 12 years. MATERIAL AND METHOD: Data of this retrospective crosssectional study was collected from 6,613 cancer patients at Prof. Dr. A. Ilhan Özdemir Education and Research Hospital between 2005- 2016. MINITAB 15 package software was used for statistical analysis. Chi-Square test and differences between two ratios significance test were used to calculate the relationship between two nominal (categorical) variables...
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29607821/human-papilloma-virus-hpv-in-sinonasal-papillomas-and-squamous-cell-carcinomas-a-pcr-based-study-of-60-cases
#9
Ambreen Beigh, Ruby Rashi, Sheikh Junaid, Mehnaz Sultan Khuroo, Summyia Farook
This study was carried out to observe the association of Human Papilloma Virus (HPV) with papillomas and squamous cell carcinomas of the sinonasal region. The present study was a hospital-based study conducted over a period of three years from May, 2014 to May, 2017 in the Department of Pathology, Government Medical College, Srinagar. A total of 196 cases of non-neoplastic and neoplastic lesions of nasal cavity and paranasal sinuses were observed during the study period. Out of total 196 cases, 102 were non-neoplastic and 94 were neoplastic...
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29607820/assessment-of-sunitinib-alternative-prescription-schedules-in-metastatic-kidney-cancer-a-study-of-10-cases
#10
Habib Diallo, Hasnae Alaoui Mhamdi, Salma Elouarzazi, Mohamed Fadli, Rhizlane Belbaraka
BACKGROUND: Managing metastatic Renal Cell Carcinoma (mRCC) has been revolutionized during the first decade of the 21st century due to the development of targeted therapies. The sunitinib is an oral multi-targeted receptor Tyrosine Kinase Inhibitor (TKI). It became the first targeted therapy as first-line treatment to improve the survival of patients with metastatic kidney cancer. This treatment consists in the oral intake of 50 mg of sunitinib per day in a 6 -week cycle including 4 weeks of treatment intake (the "on" week) followed by a 2-week break (the off week)...
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29607819/profile-of-high-grade-gliomas-a-single-center-experience
#11
Basharat Mujtaba Jan, Arif Hussain Sarmast, Abdul Rashid Bhat, Altaf Rehman Kirmani
INTRODUCTION: The term high grade glioma (HGG), is usually used to describe WHO grade III and IV tumours. There has been a recent increase in incidence of HGGs in the Western world, particularly in the elderly population. This probably reflects the easy availability of vastly improved diagnostic imaging. A five year retroprospective study was planned to study demography, clinical presentation, imaging, surgical intervention, histopathological examination of specimens and postoperative outcome of patients of high grade gliomas...
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29607818/epidemiology-of-colorectal-cancer-in-iraq-2002-2014
#12
Safauldeen Abdulrahman Al Dahhan, Faris H Al Lami
OBJECTIVES: After cardiovascular diseases, cancer is one of the major causes of death in Iraq but there is scarcity of data on cancer. This study aimed to estimate the incidence rate of colorectal cancer in Iraq and its distribution and determine its trend in Iraq from 2002 to 2011. METHODS: The necessary data for recording the incidence of colorectal cancer in Iraq were obtained from three main sources including the cancer registry for the period of 2002-2014. Data included information on gender, age, geographical distribution, site of tumors, and histology types...
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29607817/lung-cancer-epidemiology-among-the-bahraini-population-1998-2011
#13
Najat Mohamed Abulfateh, Randah R Hamadeh, Majida Fikree
BACKGROUND: Lung cancer is the fourth most common cancer in the Gulf Cooperation Council countries among males and the third among females. It is the commonest cancer among Bahraini males accounting for 16.9% of all cancers and the third in Bahraini females contributing to 5.8 % of all female cancers. The aim of this study was to describe the epidemiology of lung cancer among the Bahraini population during the period 1998-2011. METHODS: All Bahraini registered lung cancer cases in the national cancer registry from 1 January 1998 to 31 December 2011 were included in the study...
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29607816/rosai-dorfman-disease-five-years-retrospective-analysis-from-tertiary-cancer-center
#14
K Aradhana, B Thejaswini, A Shamsundar, R Nanda, Usha Amritham, G V Giri
AIM: To study the pattern of presentation and management of nodal and extranodal primary RDD. METHODOLOGY: From 2010 to 2015, eleven patients diagnosed with Rosai-Dorfman Disease (RDD) presented at our institute. Nine of them were analyzed as they received treatment at our center. We had five neck primaries, three intracranial and one cutaneous disease. Hematological, radiological, histopathological and immunohistochemistry evaluation along with the treatment data was collected and analyzed...
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29607815/cytomorphologic-spectrum-of-hurthle-cell-lesions-of-thyroid-a-study-of-54-cases
#15
K R Anila, Nileena Nayak, Preethi Sara George, K Jayasree
INTRODUCTION: Lesions of the thyroid gland composed of Hurthle cells constitute a wide spectrum of pathological entities ranging from benign hyperplastic nodules with Hurthle cell metaplasia at one end to malignancies like Hurthle cell carcinomas. The cytological distinction of these entities is not only diagnostically challenging but are also critical since they influence treatment decisions. AIM: To critically analyze the cytomorphology of cases of Hurthle cell lesions in FNACs and to characterize cytological features shown to be statistically signific ant in predicting Hurthle cell neoplasm (HCN)...
January 2018: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29019336/chemotherapy-induced-febrile-neutropenia-in-solid-tumours
#16
Ayman Rasmy, Mohammed Al Mashiakhi, Amal Ameen
Febrile neutropaenia (FN) is defined as an oral temperature of >38.3°C or two consecutive readings of >38.0°C for 2 hours and an absolute neutrophil count (ANC) of <0.5 × 109/l, or expected to fall below 0.5 × 109/l. Fever is one of the characteristic symptoms of FN and is usually associated with the presence of an infection caused by various microorganisms. The incidence and epidemiology of FN are variable based on different factors: (type of cancer, the age/sex of the patient, chemotherapy type /number of cycles)...
September 2017: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29019335/leiomyosarcoma-of-penis-an-aggressive-and-exceptionally-rare-entity
#17
Vinita Trivedi, Muneer A, Rita Rani, Richa Chauhan, Usha Singh, Naveen Kuna
Penile leiomyosarcoma is a very rare disease of penile mesenchymal tissue, most of them are of vascular origin and pathologically classified into the superficial and deep type. Because of the small number of cases reported so far, the conclusions about treatment and prognosis are equivocal. Here we report a case of 40-year old patient who presented with leiomyosracoma of penis; despite adequate surgery patient developed local recurrence and distant metastasis indicating aggressive nature of leiomyosarcoma entity of penis...
September 2017: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29019334/brain-metastasis-from-colorectal-adenocarcinoma-a-case-report
#18
Jaroslav Nemec, Abdulsalam Alnajjar, Jasem Albarrak, Shaban A, Mariam Al Otaibi, Asit Mohanty
Colorectal cancer (CRC) is the third leading cause of cancer death in the Western world, accounting for approximately 140,000 new cases and more than 51,000 deaths in 2010 in the United States. In Kuwait, CRC is the first most-diagnosed neoplasm among males and overall, the second leading cause of death from cancer. The 5-year survival rate in 2002-2004 was 61% for men and 62% for women. Even after complete resection of the colorectal tumor, distant metastases have been noted to develop in 10%-15% of patients...
September 2017: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29019333/evaluation-of-brca1-large-genomic-rearrangements-in-group-of-egyptian-female-breast-cancer-patients-using-mlpa
#19
Ola M Eid, Eman A El Ghoroury, Maha M Eid, Rana M Mahrous, Mohamed I Abdelhamid, Zahra I Aboafya, Esmat A Abdel Ghaffar, Amany H Abdelrahman
INTRODUCTION: Breast cancer is one of the most widespread cancers affecting women all over the world. In Egypt, it is considered to be the first cause of malignancies among female. BRCA1 Large Genomic Rearrangements (LGRs) have been reported in hereditary breast families and occurs in considerable proportion of cases in various populations. OBJECTIVE AND METHODS: We investigated the incidence of BRCA1 LGRs in group of Egyptian females with breast cancer using Multiplex Ligation-dependent Probe Amplification (MLPA) assay...
September 2017: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/29019332/pre-treatment-nutritional-status-and-radiotherapy-outcome-in-patients-with-locally-advanced-head-and-neck-cancers
#20
Amit Bahl, Arun Elangovan, Satinder Kaur, Rosahn Verman, Arun Singh Oinam, Sushmita Ghoshal, Naresh K Panda
AIM: Poor oral intake and associated nutritional depletion can affect treatment outcome in locally advanced head and neck cancers. The aim of this study was to evaluate the pre radiotherapy nutritional status as a predictor for response to radiotherapy treatment. PATIENTS AND METHODS: Fifty patients of locally advanced head and neck cancers undergoing radical chemoradiotherapy were evaluated in this prospective analysis. Patients were treated with definitive radiotherapy to a total dose of 60-70 Gy along with concurrent chemotherapy with injection Cisplatin 100mg/m2 delivered three weekly...
September 2017: Gulf Journal of Oncology
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