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Nature Reviews. Urology

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https://www.readbyqxmd.com/read/27898101/urinary-incontinence-detrusor-activity-predicts-renal-damage
#1
Peter Sidaway
No abstract text is available yet for this article.
November 29, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27898100/bladder-dysfunction-in-2016-new-insights-into-interstitial-cystitis-and-chronic-pelvic-pain-syndromes
#2
Jia-Fong Jhang, Hann-Chorng Kuo
No abstract text is available yet for this article.
November 29, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27898099/clinical-and-molecular-rationale-to-retain-the-cancer-descriptor-for-gleason-score-6-disease
#3
REVIEW
Chad A Reichard, Eric A Klein
Treatment choices for men with indolent prostate cancer include active surveillance or definitive local therapy. Overtreatment of these patients is an important current problem. Treatment decisions are often made jointly by the clinician and the patient, partly based on the tumour's Gleason score. To reduce the burden of overtreatment, the clinical significance of Gleason score 3 + 3 = 6 prostate cancer has been questioned and some have advocated that Gleason pattern 3 should be stripped of its cancer status...
November 29, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27898098/development-ar-signalling-and-sexual-development
#4
Louise Stone
No abstract text is available yet for this article.
November 29, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27898097/infection-siderophore-based-vaccine-protects-against-e-coli-infection
#5
Peter Sidaway
No abstract text is available yet for this article.
November 29, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27898096/on-a-fox-hunt-functions-of-fox-transcriptional-regulators-in-bladder-cancer
#6
REVIEW
Hironobu Yamashita, Vasty Osei Amponsa, Joshua I Warrick, Zongyu Zheng, Peter E Clark, Jay D Raman, Xue-Ru Wu, Cathy Mendelsohn, David J DeGraff
Genomic and transcriptional studies have identified discrete molecular subtypes of bladder cancer. These observations could be the starting point to identify new treatments. Several members of the forkhead box (FOX) superfamily of transcription factors have been found to be differentially expressed in the different bladder cancer subtypes. In addition, the FOXA protein family are key regulators of embryonic bladder development and patterning. Both experimental and clinical data support a role for FOXA1 and FOXA2 in urothelial carcinoma...
November 29, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27872478/circulating-tumour-cells-as-biomarkers-of-prostate-bladder-and-kidney-cancer
#7
REVIEW
Michael A Gorin, James E Verdone, Emma van der Toom, Trinity J Bivalacqua, Mohamad E Allaf, Kenneth J Pienta
Circulating tumour cells (CTCs) have been studied as biomarkers of a number of solid malignancies. Potential clinical applications for CTC analysis include early cancer detection, disease staging, monitoring for recurrence, prognostication, and to aid in the selection of therapy. In the field of urologic oncology, CTCs have been most widely studied as prognostic biomarkers of castration-resistant prostate cancer. Additionally, emerging data support a role for CTCs to help identify which patients are most likely to respond to novel androgen-pathway targeted therapies, such as abiraterone and enzalutamide...
November 22, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27872477/the-role-of-gata2-in-lethal-prostate-cancer-aggressiveness
#8
REVIEW
Veronica Rodriguez-Bravo, Marc Carceles-Cordon, Yujin Hoshida, Carlos Cordon-Cardo, Matthew D Galsky, Josep Domingo-Domenech
Advanced prostate cancer is a classic example of the intractability and consequent lethality that characterizes metastatic carcinomas. Novel treatments have improved the survival of men with prostate cancer; however, advanced prostate cancer invariably becomes resistant to these therapies and ultimately progresses to a lethal metastatic stage. Consequently, detailed knowledge of the molecular mechanisms that control prostate cancer cell survival and progression towards this lethal stage of disease will benefit the development of new therapeutics...
November 22, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27843146/prostate-cancer-role-for-egfr-her2-in-bone-metastasis
#9
Clemens Thoma
No abstract text is available yet for this article.
November 15, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27843145/infection-transcriptome-remodelling-explains-uti-recurrence
#10
Peter Sidaway
No abstract text is available yet for this article.
November 15, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27843144/prostate-cancer-a-glitch-in-the-extracellular-matrix
#11
Louise Stone
No abstract text is available yet for this article.
November 15, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27843142/prostate-cancer-brn2-is-a-neuroendocrine-driver
#12
Annette Fenner
No abstract text is available yet for this article.
November 15, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27824352/kidney-cancer-high-affinity-fc-%C3%AE-variants-improve-il-2-responses
#13
Peter Sidaway
No abstract text is available yet for this article.
November 8, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27824350/erectile-dysfunction-too-much-rock-erection-block
#14
Clemens Thoma
No abstract text is available yet for this article.
November 8, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27824349/urinary-incontinence-effects-of-anterior-root-stimulation-are-sustained
#15
Peter Sidaway
No abstract text is available yet for this article.
November 8, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27824348/androgen-synthesis-in-prostate-cancer-do-all-roads-lead-to-rome
#16
REVIEW
Ryan Stuchbery, Patrick J McCoy, Christopher M Hovens, Niall M Corcoran
The accumulation of high concentrations of signalling androgens within prostate tumours that progress despite use of androgen-deprivation therapy is a clinically important mechanism of the development of castration-resistant prostate cancer. In the past 5 years, data from a number of studies have increased our understanding of the enzymes and substrates involved in intratumoural androgen biosynthesis, and have implicated three competing pathways, which are likely to account for these observations. These pathways ('canonical', 'backdoor' and '5α-dione'), which can all ultimately generate the potent signalling androgen, dihydrotestosterone, involve many of the same enzymes, but differ in terms of substrate preference, reaction sequence and the organs and tissues in which they occur...
November 8, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27824347/prostate-cancer-on-target-theranostic-imaging-for-aggressive-disease
#17
Louise Stone
No abstract text is available yet for this article.
November 8, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27824346/bladder-cancer-autologous-nk-cells-active-against-high-risk-cancer
#18
Peter Sidaway
No abstract text is available yet for this article.
November 8, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27824345/kidney-cancer-somatic-mutations-predict-survival-duration
#19
Peter Sidaway
No abstract text is available yet for this article.
November 8, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27804987/kidney-cancer-methylation-panel-predicts-rcc-outcome
#20
Annette Fenner
No abstract text is available yet for this article.
November 2, 2016: Nature Reviews. Urology
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