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Nature Reviews. Urology

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https://www.readbyqxmd.com/read/29434372/a-stage-dependent-link-between-metabolic-syndrome-components-and-incident-prostate-cancer
#1
REVIEW
Jan Hammarsten, Jan-Erik Damber, Mohammad A Haghsheno, Dan Mellström, Ralph Peeker
Metabolic syndrome is associated with increased cancer risk and progression at almost all sites, including the prostate in high-stage prostate cancer. However, several reports have described an inverse relationship between metabolic syndrome and its components and low-stage incident prostate cancer. Such anomalies in cancer research hamper efforts to fight cancer. Evidence suggests that metabolic syndrome and its components have two distinct effects in prostate cancer, concealing prostate cancer in low-stage disease and promoting progression to high-stage incident, nonlocalized, and lethal prostate cancer...
February 13, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29434371/kidney-cancer-pdl1-as-a-biomarker-in-high-risk-rcc
#2
Rebecca Kelsey
No abstract text is available yet for this article.
February 13, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29434370/imaging-predicting-68ga-psma-pet-ct-positivity-for-recurrent-disease
#3
Louise Stone
No abstract text is available yet for this article.
February 13, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29434369/bladder-biomechanics-and-the-use-of-scaffolds-for-regenerative-medicine-in-the-urinary-bladder
#4
REVIEW
Fatemeh Ajalloueian, Greg Lemon, Jöns Hilborn, Ioannis S Chronakis, Magdalena Fossum
The urinary bladder is a complex organ with the primary functions of storing urine under low and stable pressure and micturition. Many clinical conditions can cause poor bladder compliance, reduced capacity, and incontinence, requiring bladder augmentation or use of regenerative techniques and scaffolds. To replicate an organ that is under frequent mechanical loading and unloading, special attention towards fulfilling its biomechanical requirements is necessary. Several biological and synthetic scaffolds are available, with various characteristics that qualify them for use in bladder regeneration in vitro and in vivo, including in the treatment of clinical conditions...
February 13, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29434368/prostate-cancer-genomic-drivers-of-resistance-to-ar-therapies
#5
Rebecca Kelsey
No abstract text is available yet for this article.
February 13, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29434367/stones-individual-gut-microbiome-in-nephrolithiasis
#6
Rebecca Kelsey
No abstract text is available yet for this article.
February 13, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29434366/potentiating-prostate-cancer-immunotherapy-with-oncolytic-viruses
#7
REVIEW
Patrick Lee, Shashi Gujar
The clinical effectiveness of immunotherapies for prostate cancer remains subpar compared with that for other cancers. The goal of most immunotherapies is the activation of immune effectors, such as T cells and natural killer cells, as the presence of these activated mediators positively correlates with patient outcomes. Clinical evidence shows that prostate cancer is immunogenic, accessible to the immune system, and can be targeted by antitumour immune responses. However, owing to the detrimental effects of prostate-cancer-associated immunosuppression, even the newest immunotherapeutic approaches fail to initiate the clinically desired antitumour immune reaction...
February 13, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29434365/bladder-cancer-bbn-mouse-model-mimics-human-mibc
#8
Rebecca Kelsey
No abstract text is available yet for this article.
February 13, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29405206/the-potential-of-3d-printing-in-urological-research-and-patient-care
#9
REVIEW
Marc Colaco, Daniel A Igel, Anthony Atala
3D printing is an evolving technology that enables the creation of unique organic and inorganic structures with high precision. In urology, the technology has demonstrated potential uses in both patient and clinician education as well as in clinical practice. The four major techniques used for 3D printing are inkjet printing, extrusion printing, laser sintering, and stereolithography. Each of these techniques can be applied to the production of models for education and surgical planning, prosthetic construction, and tissue bioengineering...
February 6, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29405205/bladder-cancer-improving-nmibc-risk-stratification
#10
Clemens Thoma
No abstract text is available yet for this article.
February 6, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29405204/labiaplasty-motivation-techniques-and-ethics
#11
REVIEW
Müjde Özer, Indiana Mortimore, Elise P Jansma, Margriet G Mullender
Labiaplasty (also known as labia minora reduction) is attracting increasing attention in the media and in online forums. Controversy exists among health-care professionals on how to manage a request for this surgery. Furthermore, the indications for and outcomes of labiaplasty have not yet been systematically assessed, and long-term outcomes have not yet been reported. Labia minora hypertrophy is defined as enlargement of the labia minora; however, the natural variation of labia minora size has scarcely been studied, with only one study suggesting objective criteria...
February 6, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29384524/infection-vaginal-microbiota-and-infectious-infertility
#12
Louise Stone
No abstract text is available yet for this article.
January 31, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29384523/a-practical-guide-to-bladder-cancer-pathology
#13
REVIEW
Eva Compérat, Justine Varinot, Julien Moroch, Caroline Eymerit-Morin, Fadi Brimo
Pathological assessment of bladder cancer is becoming an increasingly complex task owing to the growing availability of molecular data for different histological subtypes and the appreciation of their importance in determining outcomes of neoadjuvant chemotherapy. Urologists are aware of the need to closely collaborate with pathologists, and comprehensive sharing of information is crucial to achieve optimal patient management. Numerous steps towards this goal have been made during the past years. Important advances in the assessment and reporting of grading and staging, especially substaging of pT1 urothelial carcinomas, have been made...
January 31, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29384522/stepwise-sexual-development-of-adolescents-the-dutch-approach-to-sexuality-education
#14
Sanderijn van der Doef, Jo Reinders
No abstract text is available yet for this article.
January 31, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29384521/prostate-cancer-proms-suggest-a-festival-of-benefits-in-latitude
#15
Annette Fenner
No abstract text is available yet for this article.
January 31, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29359739/prostate-cancer-developing-car-t-cell-therapy
#16
Clemens Thoma
No abstract text is available yet for this article.
January 23, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29359738/prostate-cancer-revealing-mechanisms-of-resistance
#17
Louise Stone
No abstract text is available yet for this article.
January 23, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29359737/repairing-the-female-pelvic-floor-when-good-enough-is-not-good-enough
#18
Sheila MacNeil, Sohier El Neil, Gloria Esegbona, Margot Damaser
No abstract text is available yet for this article.
January 23, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29335526/prostate-cancer-race-and-prostate-cancer-personalized-medicine-the-future
#19
Stephen Freedland
No abstract text is available yet for this article.
January 16, 2018: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29335525/urothelial-cancer-optimizing-and-integrating-cisplatin-based-chemotherapy-across-the-disease-spectrum
#20
Jay D Raman
No abstract text is available yet for this article.
January 16, 2018: Nature Reviews. Urology
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