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Nature Reviews. Nephrology

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https://www.readbyqxmd.com/read/28529341/lupus-nephritis-cholesterol-accumulation-in-dcs-promotes-autoimmunity
#1
Ellen F Carney
No abstract text is available yet for this article.
May 22, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28529340/vasculitis-a-clear-argument-for-targeting-complement-in-anca-vasculitis
#2
Ralph Kettritz
No abstract text is available yet for this article.
May 22, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28529339/glomerular-disease-updated-oxford-classification-of-iga-nephropathy-a-new-mest-c-score
#3
Glen Markowitz
No abstract text is available yet for this article.
May 22, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28529338/glomerular-disease-targeted-steroid-therapy-for-iga-nephropathy
#4
Richard J Glassock
No abstract text is available yet for this article.
May 22, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28502986/autoimmunity-hla-mediated-protection-in-goodpasture-disease
#5
Ellen F Carney
No abstract text is available yet for this article.
May 15, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28502985/transplantation-anti-viral-therapy-enables-transplantation-of-hcv-kidneys
#6
Andrea Aguilar
No abstract text is available yet for this article.
May 15, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28502984/diabetic-nephropathy-glucose-metabolic-flux-in-dn
#7
Susan J Allison
No abstract text is available yet for this article.
May 15, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28502983/alkaline-phosphatase-a-novel-treatment-target-for-cardiovascular-disease-in-ckd
#8
REVIEW
Mathias Haarhaus, Vincent Brandenburg, Kamyar Kalantar-Zadeh, Peter Stenvinkel, Per Magnusson
Cardiovascular disease is the main cause of early death in the settings of chronic kidney disease (CKD), type 2 diabetes mellitus (T2DM), and ageing. Cardiovascular events can be caused by an imbalance between promoters and inhibitors of mineralization, which leads to vascular calcification. This process is akin to skeletal mineralization, which is carefully regulated and in which isozymes of alkaline phosphatase (ALP) have a crucial role. Four genes encode ALP isozymes in humans. Intestinal, placental and germ cell ALPs are tissue-specific, whereas the tissue-nonspecific isozyme of ALP (TNALP) is present in several tissues, including bone, liver and kidney...
May 15, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28480905/transplantation-the-psychology-of-extraordinary-altruism
#9
Ellen F Carney
No abstract text is available yet for this article.
May 8, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28480903/metabolic-reprogramming-in-clear-cell-renal-cell-carcinoma
#10
REVIEW
Hiromi I Wettersten, Omran Abu Aboud, Primo N Lara, Robert H Weiss
Research in many cancers has uncovered changes in metabolic pathways that control tumour energetics and biosynthesis, so-called metabolic reprogramming. Studies in clear cell renal cell carcinoma (ccRCC) have been particularly revealing, leading to the concept that ccRCC is a metabolic disease. ccRCC is generally accompanied by reprogramming of glucose and fatty acid metabolism and of the tricarboxylic acid cycle. Metabolism of tryptophan, arginine and glutamine is also reprogrammed in many ccRCCs, and these changes provide opportunities for new therapeutic strategies, biomarkers and imaging modalities...
May 8, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28366948/renal-fibrosis-pericytes-activate-complement-in-fibrosis
#11
Shimona Starling
No abstract text is available yet for this article.
April 3, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28366942/renal-and-cardiac-assessment-of-living-kidney-donor-candidates
#12
REVIEW
Ngan N Lam, Krista L Lentine, Amit X Garg
Living kidney donation provides the best therapeutic outcomes for eligible patients with end-stage renal disease. To ensure suitability for living kidney donation, donor candidates undergo a thorough medical, surgical, and psychosocial evaluation by a multidisciplinary transplant assessment team. Numerous guidelines are available to assist clinicians in the process of donor evaluation and selection. These guidelines outline the minimum recommended requirements for donor screening and additional tests that are indicated when abnormalities arise; however, evidence suggests that some of these additional tests might not be required in certain donor candidates...
April 3, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28344328/renal-physiology-hco3-reclamation-in-the-renal-proximal-tubule
#13
Ellen F Carney
No abstract text is available yet for this article.
March 27, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28287109/lupus-nephritis-t-bet-b-cells-mediate-renal-injury-in-lupus
#14
Andrea Aguilar
No abstract text is available yet for this article.
March 13, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28262772/transplantation-desensitization-and-survival-in-kidney-transplant-recipients
#15
Caner Süsal, Gerhard Opelz
No abstract text is available yet for this article.
March 6, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28480904/renal-physiology-burning-calories-to-excrete-salt
#16
Ton J Rabelink
No abstract text is available yet for this article.
June 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28480902/cardiovascular-disease-coronary-artery-calcification-predicts-risk-of-cvd-in-patients-with-ckd
#17
Paolo Raggi
No abstract text is available yet for this article.
June 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28435157/the-systemic-nature-of-ckd
#18
REVIEW
Carmine Zoccali, Raymond Vanholder, Ziad A Massy, Alberto Ortiz, Pantelis Sarafidis, Friedo W Dekker, Danilo Fliser, Denis Fouque, Gunnar H Heine, Kitty J Jager, Mehmet Kanbay, Francesca Mallamaci, Gianfranco Parati, Patrick Rossignol, Andrzej Wiecek, Gerard London
The accurate definition and staging of chronic kidney disease (CKD) is one of the major achievements of modern nephrology. Intensive research is now being undertaken to unravel the risk factors and pathophysiologic underpinnings of this disease. In particular, the relationships between the kidney and other organs have been comprehensively investigated in experimental and clinical studies in the last two decades. Owing to technological and analytical limitations, these links have been studied with a reductionist approach focusing on two organs at a time, such as the heart and the kidney or the bone and the kidney...
June 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28435156/polycystic-kidney-disease-pmm2-mutation-causes-pkd-and-hyperinsulinism
#19
Ellen F Carney
No abstract text is available yet for this article.
June 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28420887/kidney-cancer-targeting-metabolism-in-rcc
#20
Susan J Allison
No abstract text is available yet for this article.
June 2017: Nature Reviews. Nephrology
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