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Nature Reviews. Nephrology

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https://www.readbyqxmd.com/read/29151600/regenerative-medicine-a-step-closer-to-kidneys-in-a-dish
#1
Grant Otto
No abstract text is available yet for this article.
November 20, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29151599/epigenetics-ewas-of-kidney-function
#2
Jack M Heintze
No abstract text is available yet for this article.
November 20, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29151598/gene-expression-single-cell-rna-sequencing-of-collecting-duct-cells
#3
Susan J Allison
No abstract text is available yet for this article.
November 20, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29129927/nephrotic-syndrome-avil-mutations-reduce-podocyte-migration-rate-in-srns
#4
Jack M Heintze
No abstract text is available yet for this article.
November 13, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29129926/tubular-disease-anti-lrp2-nephropathy
#5
Ellen F Carney
No abstract text is available yet for this article.
November 13, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29129925/the-neural-basis-of-homeostatic-and-anticipatory-thirst
#6
REVIEW
Claire Gizowski, Charles W Bourque
Water intake is one of the most basic physiological responses and is essential to sustain life. The perception of thirst has a critical role in controlling body fluid homeostasis and if neglected or dysregulated can lead to life-threatening pathologies. Clear evidence suggests that the perception of thirst occurs in higher-order centres, such as the anterior cingulate cortex (ACC) and insular cortex (IC), which receive information from midline thalamic relay nuclei. Multiple brain regions, notably circumventricular organs such as the organum vasculosum lamina terminalis (OVLT) and subfornical organ (SFO), monitor changes in blood osmolality, solute load and hormone circulation and are thought to orchestrate appropriate responses to maintain extracellular fluid near ideal set points by engaging the medial thalamic-ACC/IC network...
November 13, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29129924/hypertension-peripheral-control-of-the-systemic-hypoxic-response
#7
Grant Otto
No abstract text is available yet for this article.
November 13, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29109546/chronic-kidney-disease-intensive-blood-pressure-reduction-lowers-mortality-in-ckd
#8
Stephen P Juraschek, Lawrence J Appel
No abstract text is available yet for this article.
November 7, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29062142/modelling-diabetic-nephropathy-in-mice
#9
REVIEW
Kengo Azushima, Susan B Gurley, Thomas M Coffman
Diabetic nephropathy (DN) is a leading cause of end-stage renal disease in the developed world. Accordingly, an urgent need exists for new, curative treatments as well as for biomarkers to stratify risk of DN among individuals with diabetes mellitus. A barrier to progress in these areas has been a lack of animal models that faithfully replicate the main features of human DN. Such models could be used to define the pathogenesis, identify drug targets and test new therapies. Owing to their tractability for genetic manipulation, mice are widely used to model human diseases, including DN...
October 24, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28989174/new-treatment-paradigms-for-adpkd-moving-towards-precision-medicine
#10
REVIEW
Matthew B Lanktree, Arlene B Chapman
The natural history of autosomal dominant polycystic kidney disease (ADPKD) is characterized by a variable rate of cyst development and increase in total kidney volume (TKV), variable kidney function decline and age of onset of end-stage renal disease (ESRD), and variable presentation of renal and extrarenal manifestations. Precision medicine is proposed to improve patient outcomes by tailoring therapy to the specific genetic background, pathophysiology, disease burden, prognosis and status of each individual...
October 9, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28869248/pre-eclampsia-screening-and-aspirin-therapy-for-prevention-of-pre-eclampsia
#11
James M Roberts, Katherine P Himes
No abstract text is available yet for this article.
September 4, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28852210/immunology-the-renal-sodium-gradient-in-antimicrobial-defence
#12
Susan J Allison
No abstract text is available yet for this article.
August 30, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29081512/developmental-biology-renewal-of-npcs-requires-myc-and-%C3%AE-catenin
#13
Jack M Heintze
No abstract text is available yet for this article.
December 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29081511/genetic-kidney-disease-uromodulin-in-er-stress-and-apoptosis
#14
Susan J Allison
No abstract text is available yet for this article.
December 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29081510/isolation-and-characterization-of-urinary-extracellular-vesicles-implications-for-biomarker-discovery
#15
REVIEW
Michael L Merchant, Ilse M Rood, Jeroen K J Deegens, Jon B Klein
Urine is a valuable diagnostic medium and, with the discovery of urinary extracellular vesicles, is viewed as a dynamic bioactive fluid. Extracellular vesicles are lipid-enclosed structures that can be classified into three categories: exosomes, microvesicles (or ectosomes) and apoptotic bodies. This classification is based on the mechanisms by which membrane vesicles are formed: fusion of multivesicular bodies with the plasma membranes (exosomes), budding of vesicles directly from the plasma membrane (microvesicles) or those shed from dying cells (apoptotic bodies)...
December 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29081509/podocytes-shca-regulates-nephrin-turnover
#16
Ellen F Carney
No abstract text is available yet for this article.
December 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29062141/immunometabolism-oxygen-sensing-and-cell-metabolism-in-inflammation
#17
Kai-Uwe Eckardt
No abstract text is available yet for this article.
December 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29033453/polycystic-kidney-disease-modulation-of-cystogenesis-by-the-microenviroment
#18
Ellen F Carney
No abstract text is available yet for this article.
December 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29033452/renal-anaemia-ipsc-derived-epo-producing-cells-rescue-anaemia
#19
Susan J Allison
No abstract text is available yet for this article.
December 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28989176/renal-physiology-er-associated-degradation-in-diabetes-insipidus
#20
Susan J Allison
No abstract text is available yet for this article.
December 2017: Nature Reviews. Nephrology
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