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Nature Reviews. Nephrology

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https://www.readbyqxmd.com/read/28344330/acute-kidney-injury-intravenous-hydration-for-the-prevention-of-ciaki
#1
Carlo Briguori, Giuseppe Signoriello
No abstract text is available yet for this article.
March 27, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28344329/glomerular-disease-mtor-in-fsgs
#2
Susan J Allison
No abstract text is available yet for this article.
March 27, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28344328/renal-physiology-hco3-reclamation-in-the-renal-proximal-tubule
#3
Ellen F Carney
No abstract text is available yet for this article.
March 27, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28316335/complement-in-anca-associated-vasculitis-mechanisms-and-implications-for-management
#4
REVIEW
Min Chen, David R W Jayne, Ming-Hui Zhao
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of potentially life-threatening autoimmune diseases. The main histological feature in the kidneys of patients with AAV is pauci-immune necrotizing crescentic glomerulonephritis with little immunoglobulin and complement deposition in the glomerular capillary walls. The complement system was not, therefore, initially thought to be associated with the development of AAV. Accumulating evidence from animal models and clinical observations indicate, however, that activation of the complement system - and the alternative pathway in particular - is crucial for the development of AAV, and that the complement activation product C5a has a central role...
March 20, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28316334/chronic-kidney-disease-uraemic-toxin-induced-platelet-hyperactivity
#5
Susan J Allison
No abstract text is available yet for this article.
March 20, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28287111/glomerular-disease-a-supar-kidney-connection-found-in-the-bone-marrow
#6
Lorenzo Gallon, Susan E Quaggin
No abstract text is available yet for this article.
March 13, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28287110/t-cells-and-autoimmune-kidney-disease
#7
REVIEW
Abel Suárez-Fueyo, Sean J Bradley, David Klatzmann, George C Tsokos
Glomerulonephritis is traditionally considered to result from the invasion of the kidney by autoantibodies and immune complexes from the circulation or following their formation in situ, and by cells of the innate and the adaptive immune system. The inflammatory response leads to the proliferation and dysfunction of cells of the glomerulus, and invasion of the interstitial space with immune cells, resulting in tubular cell malfunction and fibrosis. T cells are critical drivers of autoimmunity and related organ damage, by supporting B-cell differentiation and antibody production or by directly promoting inflammation and cytotoxicity against kidney resident cells...
March 13, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28287109/lupus-nephritis-t-bet-b-cells-mediate-renal-injury-in-lupus
#8
Andrea Aguilar
No abstract text is available yet for this article.
March 13, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28287108/alport-syndrome-ace2-administration-slows-kidney-damage
#9
Liesbet Lieben
No abstract text is available yet for this article.
March 13, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28262777/the-role-of-the-complement-system-in-diabetic-nephropathy
#10
REVIEW
Allan Flyvbjerg
The development of type 1 and type 2 diabetes mellitus has a substantial negative impact on morbidity and mortality and is responsible for substantial individual and socioeconomic costs worldwide. One of the most serious consequences of diabetes mellitus is the development of diabetic angiopathy, which manifests clinically as microvascular and macrovascular complications. One microvascular complication, diabetic nephropathy, is the most common cause of end-stage renal disease in developed countries. Although several available therapeutic interventions can delay the onset and progression of diabetic nephropathy, morbidity associated with this disease remains high and new therapeutic approaches are needed...
March 6, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28262776/hypertension-from-gwas-to-functional-genomics-based-precision-medicine
#11
David L Mattson, Mingyu Liang
No abstract text is available yet for this article.
March 6, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28262775/polycystic-kidney-disease-microrna-17-a-new-drug-target-for-adpkd
#12
Ellen F Carney
No abstract text is available yet for this article.
March 6, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28262774/genetics-apol1-risk-variants-drive-kidney-disease-in-mice
#13
Susan J Allison
No abstract text is available yet for this article.
March 6, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28262773/metabolomics-for-clinical-use-and-research-in-chronic-kidney-disease
#14
REVIEW
Berthold Hocher, Jerzy Adamski
Chronic kidney disease (CKD) has a high prevalence in the general population and is associated with high mortality; a need therefore exists for better biomarkers for diagnosis, monitoring of disease progression and therapy stratification. Moreover, very sensitive biomarkers are needed in drug development and clinical research to increase understanding of the efficacy and safety of potential and existing therapies. Metabolomics analyses can identify and quantify all metabolites present in a given sample, covering hundreds to thousands of metabolites...
March 6, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28262772/transplantation-desensitization-and-survival-in-kidney-transplant-recipients
#15
Caner Süsal, Gerhard Opelz
No abstract text is available yet for this article.
March 6, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28239175/chronic-kidney-disease-skin-sodium-linked-to-left-ventricular-hypertrophy
#16
Ellen F Carney
No abstract text is available yet for this article.
February 27, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28239174/acute-kidney-injury-benefits-of-blocking-fructokinase
#17
Katharine H Wrighton
No abstract text is available yet for this article.
February 27, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28239172/stones-a-novel-approach-to-stone-prevention-in-cystinuria
#18
Ellen F Carney
No abstract text is available yet for this article.
February 27, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28239171/dialysis-efficacy-of-tenapanor-in-hyperphosphataemia
#19
Ellen F Carney
No abstract text is available yet for this article.
February 27, 2017: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/28239170/diabetic-nephropathy-lipid-toxicity-drives-renal-disease
#20
Liesbet Lieben
No abstract text is available yet for this article.
February 27, 2017: Nature Reviews. Nephrology
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