journal
MENU ▼
Read by QxMD icon Read
search

Nature Reviews. Rheumatology

journal
https://www.readbyqxmd.com/read/28435152/systemic-lupus-erythematosus-withdrawing-standard-of-care-therapies-in-sle-trials
#1
Chi Chiu Mok
No abstract text is available yet for this article.
April 24, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28435151/osteoarthritis-targeting-peripheral-pain-neurons-in-oa
#2
Jessica McHugh
No abstract text is available yet for this article.
April 24, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28405001/dietary-factors-in-rheumatic-autoimmune-diseases-a-recipe-for-therapy
#3
REVIEW
Shani Dahan, Yahel Segal, Yehuda Shoenfeld
Today, we are facing a new era of digitization in the health care system, and with increased access to health care information has come a growing demand for safe, cost-effective and easy to administer therapies. Dietary habits have a crucial influence on human health, affecting an individual's risk for hypertension, heart disease and stroke, as well as influencing the risk of developing of cancer. Moreover, an individual's lifestyle choices can greatly influence the progression and manifestation of chronic autoimmune rheumatic diseases...
April 13, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28405000/osteoarthritis-inflammation-and-fibrosis-in-adipose-tissue-of-osteoarthritic-joints
#4
Andreea Ioan-Facsinay, Margreet Kloppenburg
No abstract text is available yet for this article.
April 13, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28404999/gout-short-telomeres-in-gout-linked-with-flares-and-cvd
#5
Sarah Onuora
No abstract text is available yet for this article.
April 13, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28381831/experimental-arthritis-il-38-promotes-anti-inflammatory-effects
#6
Dario Ummarino
No abstract text is available yet for this article.
April 6, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28381830/the-role-of-metabolism-in-the-pathogenesis-of-osteoarthritis
#7
REVIEW
Ali Mobasheri, Margaret P Rayman, Oreste Gualillo, Jérémie Sellam, Peter van der Kraan, Ursula Fearon
Metabolism is important for cartilage and synovial joint function. Under adverse microenvironmental conditions, mammalian cells undergo a switch in cell metabolism from a resting regulatory state to a highly metabolically activate state to maintain energy homeostasis. This phenomenon also leads to an increase in metabolic intermediates for the biosynthesis of inflammatory and degradative proteins, which in turn activate key transcription factors and inflammatory signalling pathways involved in catabolic processes, and the persistent perpetuation of drivers of pathogenesis...
April 6, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28381829/fine-tuning-of-immunometabolism-for-the-treatment-of-rheumatic-diseases
#8
REVIEW
Jillian P Rhoads, Amy S Major, Jeffrey C Rathmell
All immune cells depend on specific and efficient metabolic pathways to mount an appropriate response. Over the past decade, the field of immunometabolism has expanded our understanding of the various means by which cells modulate metabolism to achieve the effector functions necessary to fight infection or maintain homeostasis. Harnessing these metabolic pathways to manipulate inappropriate immune responses as a therapeutic strategy in cancer and autoimmunity has received increasing scrutiny by the scientific community...
April 6, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28381828/rheumatoid-arthritis-the-ins-and-outs-of-platelets-in-ra
#9
Isabel Andia
No abstract text is available yet for this article.
April 6, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28360424/the-emerging-safety-profile-of-jak-inhibitors-in-rheumatic-disease
#10
Kevin L Winthrop
No abstract text is available yet for this article.
March 31, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28360423/immunometabolism-in-systemic-lupus-erythematosus
#11
REVIEW
Laurence Morel
Systemic lupus erythematosus (SLE) is an autoimmune disease mediated by pathogenic autoantibodies directed against nucleoprotein complexes. Beyond the activation of autoreactive B cells, this process involves dysregulation in many other types of immune cells, including CD4(+) T cells, dendritic cells, macrophages and neutrophils. Metabolic substrate utilization and integration of cues from energy sensors are critical checkpoints of effector functions in the immune system, with common as well as cell-specific programmes...
March 31, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28360422/immunometabolism-in-early-and-late-stages-of-rheumatoid-arthritis
#12
REVIEW
Cornelia M Weyand, Jörg J Goronzy
One of the fundamental traits of immune cells in rheumatoid arthritis (RA) is their ability to proliferate, a property shared with the joint-resident cells that form the synovial pannus. The building of biomass imposes high demands for energy and biosynthetic precursors, implicating metabolic control as a basic disease mechanism. During preclinical RA, when autoreactive T cells expand and immunological tolerance is broken, the main sites of disease are the secondary lymphoid tissues. Naive CD4(+) T cells from patients with RA have a distinct metabolic signature, characterized by dampened glycolysis, low ATP levels and enhanced shunting of glucose into the pentose phosphate pathway...
March 31, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28331210/infection-therapeutics-and-risk-of-infection-in-pregnancy
#13
Jessica McHugh
No abstract text is available yet for this article.
March 23, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28331209/systemic-lupus-erythematosus-defective-cd11b-raises-ifn-levels-in-sle
#14
Joanna Collison
No abstract text is available yet for this article.
March 23, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28331208/metabolic-regulation-of-inflammation
#15
REVIEW
Timo Gaber, Cindy Strehl, Frank Buttgereit
Immune cells constantly patrol the body via the bloodstream and migrate into multiple tissues where they face variable and sometimes demanding environmental conditions. Nutrient and oxygen availability can vary during homeostasis, and especially during the course of an immune response, creating a demand for immune cells that are highly metabolically dynamic. As an evolutionary response, immune cells have developed different metabolic programmes to supply them with cellular energy and biomolecules, enabling them to cope with changing and challenging metabolic conditions...
March 23, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28331207/osteroarthritis-a-new-tool-for-measuring-synovial-inflammation
#16
Jessica McHugh
No abstract text is available yet for this article.
March 23, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28331206/risk-factors-generational-differences-in-arthritis-prevalence
#17
Jessica McHugh
No abstract text is available yet for this article.
March 23, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28331205/therapy-monitoring-risk-of-anterior-uveitis-in-as
#18
Jessica McHugh
No abstract text is available yet for this article.
March 23, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28298650/systemic-sclerosis-knocking-out-fli1-to-clear-the-aire
#19
Jessica McHugh
No abstract text is available yet for this article.
March 16, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28298649/spondyloarthropathies-how-should-axial-spondyloarthritis-be-diagnosed
#20
Jürgen Braun, Uta Kiltz
No abstract text is available yet for this article.
March 16, 2017: Nature Reviews. Rheumatology
journal
journal
42299
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"