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Nature Reviews. Rheumatology

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https://www.readbyqxmd.com/read/30659245/neuropsychiatric-lupus-new-mechanistic-insights-and-future-treatment-directions
#1
REVIEW
Noa Schwartz, Ariel D Stock, Chaim Putterman
Patients with systemic lupus erythematosus (SLE) frequently show symptoms of central nervous system (CNS) involvement, termed neuropsychiatric SLE (NPSLE). The CNS manifestations of SLE are diverse and have a broad spectrum of severity and prognostic implications. Patients with NPSLE typically present with nonspecific symptoms, such as headache and cognitive impairment, but might also experience devastating features, such as memory loss, seizures and stroke. Some features of NPSLE, in particular those related to coagulopathy, have been characterized and an evidence-based treatment algorithm is available...
January 18, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30655606/author-correction-pathogenesis-and-therapeutic-interventions-for-anca-associated-vasculitis
#2
Daigo Nakazawa, Sakiko Masuda, Utano Tomaru, Akihiro Ishizu
In the originally published online version of this article there were errors in the Supplementary Information. All three Supplementary Tables had incorrectly numbered references. These errors have now been corrected in the HTML and PDF versions of the manuscript.
January 17, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30644453/promising-drug-delivery-system
#3
Jessica McHugh
No abstract text is available yet for this article.
January 15, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30643232/ivd-progenitor-cells-a-new-horizon-for-understanding-disc-homeostasis-and-repair
#4
REVIEW
Feng-Juan Lyu, Kenneth M Cheung, Zhaomin Zheng, Hua Wang, Daisuke Sakai, Victor Y Leung
Intervertebral disc (IVD) degeneration is associated with low back pain. In IVDs, a high mechanical load, high osmotic pressure and hypoxic conditions create a hostile microenvironment for resident cells. How IVD homeostasis and function are maintained under stress remains to be understood; however, several research groups have reported isolating native endogenous progenitor-like or otherwise proliferative cells from the IVD. The isolation of such cells implies that the IVD might contain a quiescent progenitor-like population that could be activated for IVD repair and regeneration...
January 14, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30643231/author-correction-pathogenic-bone-marrow-b-cells
#5
Nicholas J Bernard
In the originally published online version of this article there was an error in the page number of the reference to the original article published in Nature Communications, and the associated link was therefore incorrect. The page number was listed as 5217 and should have been 5127. This error has now been corrected in the HTML and PDF versions of the manuscript.
January 14, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30626908/acpa-epitopes-what-are-we-actually-looking-at
#6
Lotte A van de Stadt, Theo Rispens
No abstract text is available yet for this article.
January 9, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30626907/pathogenic-bone-marrow-b-cells
#7
Nicholas J Bernard
No abstract text is available yet for this article.
January 9, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30622298/dietary-modulation-of-the-microbiome-as-therapy
#8
Nicholas J Bernard
No abstract text is available yet for this article.
January 8, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30622297/selective-janus-kinase-inhibitors-come-of-age
#9
John J O'Shea, Massimo Gadina
No abstract text is available yet for this article.
January 8, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30622296/moving-towards-tissue-engineered-disc-replacement
#10
Jessica McHugh
No abstract text is available yet for this article.
January 8, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30617266/extracellular-matrix-in-the-crosshairs
#11
Joanna Collison
No abstract text is available yet for this article.
January 7, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30617265/cell-migration-implications-for-repair-and-regeneration-in-joint-disease
#12
REVIEW
Feini Qu, Farshid Guilak, Robert L Mauck
Connective tissues within the synovial joints are characterized by their dense extracellular matrix and sparse cellularity. With injury or disease, however, tissues commonly experience an influx of cells owing to proliferation and migration of endogenous mesenchymal cell populations, as well as invasion of the tissue by other cell types, including immune cells. Although this process is critical for successful wound healing, aberrant immune-mediated cell infiltration can lead to pathological inflammation of the joint...
January 7, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30617264/cancer-risk-associated-with-anti-tif1-antibodies
#13
Joanna Collison
No abstract text is available yet for this article.
January 7, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30617263/no-increased-risk-of-vte-with-tofacitinib
#14
Joanna Collison
No abstract text is available yet for this article.
January 7, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30617262/sustained-remission-in-psa-with-secukinumab
#15
Joanna Collison
No abstract text is available yet for this article.
January 7, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30617261/gag-metabolism-associated-with-psa-risk
#16
Joanna Collison
No abstract text is available yet for this article.
January 7, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30610219/pathophysiology-assessment-and-treatment-of-psoriatic-dactylitis
#17
REVIEW
Dennis McGonagle, Ai Lyn Tan, Abdulla Watad, Philip Helliwell
Dactylitis is diffuse swelling of the digits that is usually related to an underlying inflammatory or infiltrative disorder. Psoriatic arthritis (PsA) is the most common severe disease thought to cause dactylitis. Our understanding of the pathogenesis of PsA-related dactylitis comes from experimental animal models of PsA-like disease, as well as advances in imaging and other clinical studies. Clinical trials in PsA have increasingly included dactylitis as an important secondary outcome measure. These studies indicate that cytokines drive multi-locus microanatomical pan-digital pathology...
January 4, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30610218/overcoming-natural-wnt-inhibition-to-optimize-therapy
#18
Natalie A Sims
No abstract text is available yet for this article.
January 4, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30607012/the-microbiome-in-sle-pathogenesis
#19
Gregg J Silverman
No abstract text is available yet for this article.
January 3, 2019: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/30560909/cell-metabolism-as-a-potentially-targetable-pathway-in-ra
#20
Trudy McGarry, Ursula Fearon
No abstract text is available yet for this article.
December 18, 2018: Nature Reviews. Rheumatology
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