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Nature Reviews. Rheumatology

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https://www.readbyqxmd.com/read/28331210/infection-therapeutics-and-risk-of-infection-in-pregnancy
#1
Jessica McHugh
No abstract text is available yet for this article.
March 23, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28331209/systemic-lupus-erythematosus-defective-cd11b-raises-ifn-levels-in-sle
#2
Joanna Collison
No abstract text is available yet for this article.
March 23, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28331208/metabolic-regulation-of-inflammation
#3
REVIEW
Timo Gaber, Cindy Strehl, Frank Buttgereit
Immune cells constantly patrol the body via the bloodstream and migrate into multiple tissues where they face variable and sometimes demanding environmental conditions. Nutrient and oxygen availability can vary during homeostasis, and especially during the course of an immune response, creating a demand for immune cells that are highly metabolically dynamic. As an evolutionary response, immune cells have developed different metabolic programmes to supply them with cellular energy and biomolecules, enabling them to cope with changing and challenging metabolic conditions...
March 23, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28331207/osteroarthritis-a-new-tool-for-measuring-synovial-inflammation
#4
Jessica McHugh
No abstract text is available yet for this article.
March 23, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28331206/risk-factors-generational-differences-in-arthritis-prevalence
#5
Jessica McHugh
No abstract text is available yet for this article.
March 23, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28331205/therapy-monitoring-risk-of-anterior-uveitis-in-as
#6
Jessica McHugh
No abstract text is available yet for this article.
March 23, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28298650/systemic-sclerosis-knocking-out-fli1-to-clear-the-aire
#7
Jessica McHugh
No abstract text is available yet for this article.
March 16, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28298649/spondyloarthropathies-how-should-axial-spondyloarthritis-be-diagnosed
#8
Jürgen Braun, Uta Kiltz
No abstract text is available yet for this article.
March 16, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28298648/lupus-nephritis-novel-role-for-baff-in-tertiary-lymphoid-neogenesis
#9
Joanna Collison
No abstract text is available yet for this article.
March 16, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28275265/beyond-citrullination-other-post-translational-protein-modifications-in-rheumatoid-arthritis
#10
REVIEW
Leendert A Trouw, Theo Rispens, Rene E M Toes
The presence of autoantibodies is one of the hallmarks of rheumatoid arthritis (RA). In the past few decades, rheumatoid factors (autoantibodies that recognize the Fc-tail of immunoglobulins) as well as anti-citrullinated protein antibodies (ACPAs) have been studied intensively. ACPAs recognize post-translationally modified proteins in which the amino acid arginine has been converted into a citrulline. More recently, other autoantibody systems recognizing post-translationally modified proteins have also gained attention, including autoantibodies recognizing fragmented immunoglobulin (anti-hinge antibodies), autoantibodies recognizing acetylated proteins and autoantibodies recognizing proteins that are modified by adducts formed under oxidative stress...
March 9, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28275261/bone-osteoblasts-and-global-energy-metabolism-beyond-osteocalcin
#11
Hong Zhou, Markus J Seibel
No abstract text is available yet for this article.
March 9, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28250464/immunometabolism-il-37-fights-inflammation-induced-fatigue
#12
Sarah Onuora
No abstract text is available yet for this article.
March 2, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28202911/what-rheumatologists-need-to-know-about-crispr-cas9
#13
REVIEW
Gary J Gibson, Maozhou Yang
CRISPR/Cas9 genome editing technology has taken the research world by storm since its use in eukaryotes was first proposed in 2012. Publications describing advances in technology and new applications have continued at an unrelenting pace since that time. In this Review, we discuss the application of CRISPR/Cas9 for creating gene mutations - the application that initiated the current avalanche of interest - and new developments that have largely answered initial concerns about its specificity and ability to introduce new gene sequences...
February 9, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28077867/microbiome-in-2016-t-follicular-helper-cells-and-the-gut-microbiome-in-arthritis
#14
Veena Taneja
No abstract text is available yet for this article.
January 12, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28077865/systemic-sclerosis-in-2016-dermal-white-adipose-tissue-implicated-in-ssc-pathogenesis
#15
John Varga, Roberta G Marangoni
No abstract text is available yet for this article.
January 12, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28053336/leptin-in-the-interplay-of-inflammation-metabolism-and-immune-system-disorders
#16
REVIEW
Vanessa Abella, Morena Scotece, Javier Conde, Jesús Pino, Miguel Angel Gonzalez-Gay, Juan J Gómez-Reino, Antonio Mera, Francisca Lago, Rodolfo Gómez, Oreste Gualillo
Leptin is one of the most relevant factors secreted by adipose tissue and the forerunner of a class of molecules collectively called adipokines. Initially discovered in 1994, its crucial role as a central regulator in energy homeostasis has been largely described during the past 20 years. Once secreted into the circulation, leptin reaches the central and peripheral nervous systems and acts by binding and activating the long form of leptin receptor (LEPR), regulating appetite and food intake, bone mass, basal metabolism, reproductive function and insulin secretion, among other processes...
January 5, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28053334/rheumatoid-arthritis-new-model-linking-periodontitis-and-ra
#17
Jessica McHugh
No abstract text is available yet for this article.
January 5, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28053332/regenerative-medicine-in-2016-important-milestones-on-the-way-to-clinical-translation
#18
Daniel A Grande
No abstract text is available yet for this article.
January 5, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28053331/immune-resolution-mechanisms-in-inflammatory-arthritis
#19
REVIEW
Mauro Perretti, Dianne Cooper, Jesmond Dalli, Lucy V Norling
The past two decades have witnessed major advancements in the clinical management of inflammatory arthritis, with new treatment strategies in some cases providing a marked improvement in patient outcomes. However, it is widely accepted that current strategies do not provide the 'total therapeutic solution', in view of the proportion of patients who do not respond to therapy, the important incidence of adverse effects and the development of an immune response against antibodies or fusion proteins used therapeutically...
January 5, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28275264/experimental-arthritis-do-you-want-to-treat-arthritis-ido2
#20
Joanna Collison
No abstract text is available yet for this article.
April 2017: Nature Reviews. Rheumatology
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