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Nature Reviews. Rheumatology

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https://www.readbyqxmd.com/read/29323347/rheumatoid-arthritis-ifn%C3%AE-drives-synovial-tissue-remodelling
#1
Jessica McHugh
No abstract text is available yet for this article.
January 11, 2018: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29323346/inflammation-in-2017-connectivity-to-other-fields-brings-new-ideas
#2
Pierre Miossec
No abstract text is available yet for this article.
January 11, 2018: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29323345/osteoporosis-in-2017-addressing-the-crisis-in-the-treatment-of-osteoporosis
#3
Christian Roux, Karine Briot
No abstract text is available yet for this article.
January 11, 2018: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29323344/updating-osteoimmunology-regulation-of-bone-cells-by-innate-and-adaptive-immunity
#4
REVIEW
Matthew C Walsh, Noriko Takegahara, Hyunsoo Kim, Yongwon Choi
Osteoimmunology encompasses all aspects of the cross-regulation of bone and the immune system, including various cell types, signalling pathways, cytokines and chemokines, under both homeostatic and pathogenic conditions. A number of key areas are of increasing interest and relevance to osteoimmunology researchers. Although rheumatoid arthritis has long been recognized as one of the most common autoimmune diseases to affect bone integrity, researchers have focused increased attention on understanding how molecular triggers and innate signalling pathways (such as Toll-like receptors and purinergic signalling pathways) related to pathogenic and/or commensal microbiota are relevant to bone biology and rheumatic diseases...
January 11, 2018: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29323343/targeting-lymphatic-function-as-a-novel-therapeutic-intervention-for-rheumatoid-arthritis
#5
REVIEW
Echoe M Bouta, Richard D Bell, Homaira Rahimi, Lianping Xing, Ronald W Wood, Clifton O Bingham, Christopher T Ritchlin, Edward M Schwarz
Although clinical outcomes for patients with rheumatoid arthritis (RA) have greatly improved with the use of biologic and conventional DMARDs, approximately 40% of patients do not achieve primary clinical outcomes in randomized trials, and only a small proportion achieve lasting remission. Over the past decade, studies in murine models point to the critical role of the lymphatic system in the pathogenesis and therapy of inflammatory-erosive arthritis, presumably by the removal of catabolic factors, cytokines and inflammatory cells from the inflamed synovium...
January 11, 2018: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29323342/paediatric-rheumatology-in-2017-child-centred-research-is-the-key-to-progress
#6
Michael W Beresford, Athimalaipet V Ramanan
No abstract text is available yet for this article.
January 11, 2018: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29323341/rheumatoid-arthritis-in-2017-protective-dietary-and-hormonal-factors-brought-to-light
#7
Jeffrey A Sparks, Karen H Costenbader
No abstract text is available yet for this article.
January 11, 2018: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29323340/osteoarthritis-in-2017-latest-advances-in-the-management-of-knee-oa
#8
Timothy E McAlindon, Raveendhara R Bannuru
No abstract text is available yet for this article.
January 11, 2018: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29296024/beh%C3%A3-et-syndrome-a-contemporary-view
#9
REVIEW
Hasan Yazici, Emire Seyahi, Gulen Hatemi, Yusuf Yazici
The presence of symptom clusters, regional differences in disease expression and similarities with, for example, Crohn's disease suggest multiple pathological pathways are involved in Behçet syndrome. These features also make formulating disease criteria difficult. Genetic studies have identified HLA-B*51 to be the important genetic risk factor. However, the low prevalence of HLA-B*51 in many patients with bone fide disease, especially in non-endemic regions, suggests other factors must also be operative in Behçet syndrome...
January 3, 2018: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29296023/autoinflammatory-diseases-tnf-drives-cryopyrinopathies-in-mice
#10
Sarah Onuora
No abstract text is available yet for this article.
January 3, 2018: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29263377/systemic-lupus-erythematosus-rituximab-improves-sle-disease-activity
#11
Sarah Onuora
No abstract text is available yet for this article.
December 21, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29263376/therapy-biologics-and-risk-of-second-malignant-neoplasm
#12
Sarah Onuora
No abstract text is available yet for this article.
December 21, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29263375/osteoarthritis-arthroscopy-does-not-delay-tka-for-knee-oa
#13
Sarah Onuora
No abstract text is available yet for this article.
December 21, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29263374/rheumatoid-arthritis-higher-disease-risk-in-children-of-women-with-ra
#14
Sarah Onuora
No abstract text is available yet for this article.
December 21, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29213125/the-role-of-semaphorins-in-immune-responses-and-autoimmune-rheumatic-diseases
#15
REVIEW
Masayuki Nishide, Atsushi Kumanogoh
Semaphorins have a well-characterized role in guiding axon repulsion during development; however, the important contribution of these proteins in immunity is becoming increasingly clear. Immunoregulatory semaphorins, termed 'immune semaphorins', have roles in regulating immune cell activation, differentiation, mobility and migration. These proteins are also intimately associated with the pathogenesis of autoimmune diseases including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), systemic sclerosis (SSc) and anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV)...
December 7, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29213124/the-ra-map-consortium-a-working-model-for-academia-industry-collaboration
#16
REVIEW
Andrew P Cope, Michael R Barnes, Alexandra Belson, Michael Binks, Sarah Brockbank, Francisco Bonachela-Capdevila, Claudio Carini, Benjamin A Fisher, Carl S Goodyear, Paul Emery, Michael R Ehrenstein, Neil Gozzard, Ray Harris, Sally Hollis, Sarah Keidel, Marc Levesque, Catharina Lindholm, Michael F McDermott, Iain B McInnes, Christopher M Mela, Gerry Parker, Simon Read, Ayako Wakatsuki Pedersen, Frederique Ponchel, Duncan Porter, Ravi Rao, Anthony Rowe, Peter Schulze-Knappe, Matthew A Sleeman, Deborah Symmons, Peter C Taylor, Brian Tom, Wayne Tsuji, Denny Verbeeck, John D Isaacs
Collaboration can be challenging; nevertheless, the emerging successes of large, multi-partner, multi-national cooperatives and research networks in the biomedical sector have sustained the appetite of academics and industry partners for developing and fostering new research consortia. This model has percolated down to national funding agencies across the globe, leading to funding for projects that aim to realise the true potential of genomic medicine in the 21st century and to reap the rewards of 'big data'...
December 7, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29213123/therapy-rheumatic-symptoms-associated-with-immune-checkpoint-inhibition
#17
Jessica McHugh
No abstract text is available yet for this article.
December 7, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29213122/spondyloarthropathies-tnf-inhibitors-and-structural-damage-in-ankylosing-spondylitis
#18
Atul Deodhar
No abstract text is available yet for this article.
December 7, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29187742/bone-dj-1-orchestrates-osteoclastogenesis
#19
Joanna Collison
No abstract text is available yet for this article.
November 30, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29167547/crystal-arthritis-stepping-up-febuxostat-to-treat-gout-flares
#20
Joanna Collison
No abstract text is available yet for this article.
November 23, 2017: Nature Reviews. Rheumatology
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