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Nature Reviews. Gastroenterology & Hepatology

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https://www.readbyqxmd.com/read/29162936/liver-cancer-a-complex-interplay-between-inflammation-and-immunity-in-liver-cancer
#1
Katrina Ray
No abstract text is available yet for this article.
November 22, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29162935/hepatitis-e-virus-advances-and-challenges
#2
REVIEW
Ila Nimgaonkar, Qiang Ding, Robert E Schwartz, Alexander Ploss
At least 20 million hepatitis E virus (HEV) infections occur annually, with >3 million symptomatic cases and ∼60,000 fatalities. Hepatitis E is generally self-limiting, with a case fatality rate of 0.5-3% in young adults. However, it can cause up to 30% mortality in pregnant women in the third trimester and can become chronic in immunocompromised individuals, such as those receiving organ transplants or chemotherapy and individuals with HIV infection. HEV is transmitted primarily via the faecal-oral route and was previously thought to be a public health concern only in developing countries...
November 22, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29139482/opioid-misuse-in-gastroenterology-and-non-opioid-management-of-abdominal-pain
#3
REVIEW
Eva Szigethy, Mitchell Knisely, Douglas Drossman
Opioids were one of the earliest classes of medications used for pain across a variety of conditions, but morbidity and mortality have been increasingly associated with their chronic use. Despite these negative consequences, chronic opioid use is increasing worldwide, with the USA and Canada having the highest rates. Chronic opioid use for noncancer pain can have particularly negative effects in the gastrointestinal and central nervous systems, including opioid-induced constipation, narcotic bowel syndrome, worsening psychopathology and addiction...
November 15, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29139481/pancreatic-cancer-tailored-therapy-for-pancreatic-tumour-subtype
#4
Iain Dickson
No abstract text is available yet for this article.
November 15, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29139480/position-paper-the-potential-role-of-optical-biopsy-in-the-study-and-diagnosis-of-environmental-enteric-dysfunction
#5
REVIEW
Alex J Thompson, Michael Hughes, Salzitsa Anastasova, Laurie S Conklin, Tudor Thomas, Cadman Leggett, William A Faubion, Thomas J Miller, Peter Delaney, François Lacombe, Sacha Loiseau, Alexander Meining, Rebecca Richards-Kortum, Guillermo J Tearney, Paul Kelly, Guang-Zhong Yang
Environmental enteric dysfunction (EED) is a disease of the small intestine affecting children and adults in low and middle income countries. Arising as a consequence of repeated infections, gut inflammation results in impaired intestinal absorptive and barrier function, leading to poor nutrient uptake and ultimately to stunting and other developmental limitations. Progress towards new biomarkers and interventions for EED is hampered by the practical and ethical difficulties of cross-validation with the gold standard of biopsy and histology...
November 15, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29139479/ibd-inflammatory-biomarkers-improve-management-of-crohn-s-disease
#6
Hugh Thomas
No abstract text is available yet for this article.
November 15, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29114102/surgery-robotic-assistance-confers-no-benefit-in-rectal-cancer-surgery
#7
Hugh Thomas
No abstract text is available yet for this article.
November 8, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29114101/gut-microbiota-oral-bacteria-a-cause-of-ibd
#8
Iain Dickson
No abstract text is available yet for this article.
November 8, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29094726/ibd-the-changing-epidemiology-of-ibd
#9
Katrina Ray
No abstract text is available yet for this article.
November 2, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29094725/therapy-the-attraction-of-nivolumab-for-gastric-and-gastro-oesophageal-junction-cancer
#10
Katrina Ray
No abstract text is available yet for this article.
November 2, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29094724/gut-microbiota-oral-microbiome-could-provide-clues-to-crc
#11
Katrina Ray
No abstract text is available yet for this article.
November 2, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29094723/liver-cancer-sensitizing-hepatocellular-carcinoma-to-oncolytic-virus-therapy
#12
Jennifer Altomonte
No abstract text is available yet for this article.
November 2, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29094722/evaluation-of-indeterminate-biliary-strictures
#13
Christopher L Bowlus, Kristin A Olson, M Eric Gershwin
This corrects the article DOI: 10.1038/nrgastro.2015.182.
November 2, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29094721/colorectal-cancer-mir-100-and-mir-125b-induce-cetuximab-resistance-in-crc
#14
Hugh Thomas
No abstract text is available yet for this article.
November 2, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29066857/alcoholic-liver-disease-gut-liver-axis-ppis-enterococcus-and-promotion-of-alcoholic-liver-disease
#15
Katrina Ray
No abstract text is available yet for this article.
October 25, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29042692/nafld-hif2%C3%AE-a-new-therapeutic-target-for-nafld
#16
Iain Dickson
No abstract text is available yet for this article.
October 18, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29042691/gastric-cancer-the-gastric-microbiota-bacterial-diversity-and-implications
#17
Manish A Shah
No abstract text is available yet for this article.
October 18, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29018278/coeliac-disease-to-biopsy-or-not
#18
REVIEW
Norelle R Reilly, Steffen Husby, David S Sanders, Peter H R Green
Coeliac disease is increasingly recognized as a global problem in both children and adults. Traditionally, the findings of characteristic changes of villous atrophy and increased intraepithelial lymphocytosis identified in duodenal biopsy samples taken during upper gastrointestinal endoscopy have been required for diagnosis. Although biopsies remain advised as necessary for the diagnosis of coeliac disease in adults, European guidelines for children provide a biopsy-sparing diagnostic pathway. This approach has been enabled by the high specificity and sensitivity of serological testing...
October 11, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29018276/ibd-step-up-vs-top-down-therapy-for-crohn-s-disease-medicine-vs-surgery
#19
Bo Shen
No abstract text is available yet for this article.
October 11, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29018272/bile-acid-microbiota-crosstalk-in-gastrointestinal-inflammation-and-carcinogenesis
#20
REVIEW
Wei Jia, Guoxiang Xie, Weiping Jia
Emerging evidence points to a strong association between the gut microbiota and the risk, development and progression of gastrointestinal cancers such as colorectal cancer (CRC) and hepatocellular carcinoma (HCC). Bile acids, produced in the liver, are metabolized by enzymes derived from intestinal bacteria and are critically important for maintaining a healthy gut microbiota, balanced lipid and carbohydrate metabolism, insulin sensitivity and innate immunity. Given the complexity of bile acid signalling and the direct biochemical interactions between the gut microbiota and the host, a systems biology perspective is required to understand the liver-bile acid-microbiota axis and its role in gastrointestinal carcinogenesis to reverse the microbiota-mediated alterations in bile acid metabolism that occur in disease states...
October 11, 2017: Nature Reviews. Gastroenterology & Hepatology
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