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Nature Reviews. Endocrinology

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https://www.readbyqxmd.com/read/28059159/obesity-methylation-a-consequence-not-a-cause
#1
Tim Geach
No abstract text is available yet for this article.
January 6, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28059158/thyroid-cancer-overdiagnosis-of-papillary-carcinoma-who-benefits
#2
Juan P Brito, Ian D Hay
No abstract text is available yet for this article.
January 6, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28059157/healthy-ageing-in-2016-obesity-in-geroscience-is-cellular-senescence-the-culprit
#3
Claudio Franceschi
No abstract text is available yet for this article.
January 6, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28059156/genetic-screening-in-arterial-hypertension
#4
REVIEW
Gian Paolo Rossi, Giulio Ceolotto, Brasilina Caroccia, Livia Lenzini
Studies involving adoptive families and twins have demonstrated the genetic basis of hypertension and shown that genetic factors account for about 40% of the variance in blood pressure among individuals. Arterial hypertension is genetically complex: multiple genes influence the blood pressure phenotype through allelic effects from single genes and gene-gene interactions. Moreover, environmental factors also modify the blood pressure phenotype. This complexity explains why the identification of the underlying genes has not been as successful in hypertension as in other diseases (such as type 1 and type 2 diabetes mellitus)...
January 6, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28051119/exercise-metabolism-in-2016-health-benefits-of-exercise-more-than-meets-the-eye
#5
Mark A Febbraio
No abstract text is available yet for this article.
January 4, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28051118/adipose-tissue-a-new-generation-of-ppar%C3%AE-agonists
#6
Tim Geach
No abstract text is available yet for this article.
January 4, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28051115/therapy-once-weekly-growth-hormone
#7
Claire Greenhill
No abstract text is available yet for this article.
January 4, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/27983737/obesity-obesity-alters-fatty-acid-sensing
#8
Tim Geach
No abstract text is available yet for this article.
December 16, 2016: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/27983736/fgf21-and-metabolic-disease-in-2016-a-new-frontier-in-fgf21-biology
#9
Matthew J Potthoff
No abstract text is available yet for this article.
December 16, 2016: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/27983735/dyslipidaemia-predicting-the-benefits-and-risks-of-pcsk9-inhibition
#10
David Holmes
No abstract text is available yet for this article.
December 16, 2016: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/27934865/adipose-tissue-reversing-age-related-decline-in-beiging
#11
Tim Geach
No abstract text is available yet for this article.
December 9, 2016: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/27934864/an-updated-view-of-hypothalamic-vascular-pituitary-unit-function-and-plasticity
#12
REVIEW
Paul Le Tissier, Pauline Campos, Chrystel Lafont, Nicola Roman├▓, David J Hodson, Patrice Mollard
The discoveries of novel functional adaptations of the hypothalamus and anterior pituitary gland for physiological regulation have transformed our understanding of their interaction. The activity of a small proportion of hypothalamic neurons can control complex hormonal signalling, which is disconnected from a simple stimulus and the subsequent hormone secretion relationship and is dependent on physiological status. The interrelationship of the terminals of hypothalamic neurons and pituitary cells with the vasculature has an important role in determining the pattern of neurohormone exposure...
December 9, 2016: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/27934863/metabolism-intestinal-microbiota-affects-host-physiology
#13
Claire Greenhill
No abstract text is available yet for this article.
December 9, 2016: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/27910881/gut-microbiota-mucin-munching-bacteria-modulate-glucose-metabolism
#14
Tim Geach
No abstract text is available yet for this article.
December 2, 2016: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/27910880/diabetes-high-diabetes-mellitus-linked-mortality-in-mexico
#15
Charlotte Ridler
No abstract text is available yet for this article.
December 2, 2016: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/27910879/cardiovascular-endocrinology-spermidine-enhances-cardiovascular-health
#16
Charlotte Ridler
No abstract text is available yet for this article.
December 2, 2016: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/27910878/lipids-celastrol-protects-against-fatty-liver-through-sirt1
#17
Charlotte Ridler
No abstract text is available yet for this article.
December 2, 2016: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/27857130/early-life-exposure-to-edcs-role-in-childhood-obesity-and-neurodevelopment
#18
REVIEW
Joseph M Braun
Endocrine-disrupting chemicals (EDCs) might increase the risk of childhood diseases by disrupting hormone-mediated processes that are critical for growth and development during gestation, infancy and childhood. The fetus, infant and child might have enhanced sensitivity to environmental stressors such as EDCs due to their rapid development and increased exposure to some EDCs as a consequence of development-specific behaviour, anatomy and physiology. In this Review, I discuss epidemiological studies examining the relationship between early-life exposure to bisphenol A (BPA), phthalates, triclosan and perfluoroalkyl substances (PFAS) with childhood neurobehavioural disorders and obesity...
November 18, 2016: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/27857127/consensus-statement-on-next-generation-sequencing-based-diagnostic-testing-of-hereditary-phaeochromocytomas-and-paragangliomas
#19
Rodrigo A Toledo, Nelly Burnichon, Alberto Cascon, Diana E Benn, Jean-Pierre Bayley, Jenny Welander, Carli M Tops, Helen Firth, Trish Dwight, Tonino Ercolino, Massimo Mannelli, Giuseppe Opocher, Roderick Clifton-Bligh, Oliver Gimm, Eamonn R Maher, Mercedes Robledo, Anne-Paule Gimenez-Roqueplo, Patricia L M Dahia
Phaeochromocytomas and paragangliomas (PPGLs) are neural-crest-derived tumours of the sympathetic or parasympathetic nervous system that are often inherited and are genetically heterogeneous. Genetic testing is recommended for patients with these tumours and for family members of patients with hereditary forms of PPGLs. Due to the large number of susceptibility genes implicated in the diagnosis of inherited PPGLs, next-generation sequencing (NGS) technology is ideally suited for carrying out genetic screening of these individuals...
November 18, 2016: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/27834384/clinical-pancreatic-islet-transplantation
#20
REVIEW
A M James Shapiro, Marta Pokrywczynska, Camillo Ricordi
Clinical pancreatic islet transplantation can be considered one of the safest and least invasive transplant procedures. Remarkable progress has occurred in both the technical aspects of islet cell processing and the outcomes of clinical islet transplantation. With >1,500 patients treated since 2000, this therapeutic strategy has moved from a curiosity to a realistic treatment option for selected patients with type 1 diabetes mellitus (that is, those with hypoglycaemia unawareness, severe hypoglycaemic episodes and glycaemic lability)...
November 11, 2016: Nature Reviews. Endocrinology
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