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Nature Reviews. Endocrinology

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https://www.readbyqxmd.com/read/28820505/gut-microbiota-gas-induced-glp1-release
#1
David Holmes
No abstract text is available yet for this article.
August 18, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28820504/diabetes-insulin-pumps-after-injections-and-cgm-in-t1dm
#2
John C Pickup
No abstract text is available yet for this article.
August 18, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28820503/diabetes-systemic-effects-of-metformin-revealed
#3
Alan Morris
No abstract text is available yet for this article.
August 18, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28799554/adapting-to-obesity-with-adipose-tissue-inflammation
#4
REVIEW
Shannon M Reilly, Alan R Saltiel
Adipose tissue not only has an important role in the storage of excess nutrients but also senses nutrient status and regulates energy mobilization. An overall positive energy balance is associated with overnutrition and leads to excessive accumulation of fat in adipocytes. These cells respond by initiating an inflammatory response that, although maladaptive in the long run, might initially be a physiological response to the stresses obesity places on adipose tissue. In this Review, we characterize adipose tissue inflammation and review the current knowledge of what triggers obesity-associated inflammation in adipose tissue...
August 11, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28799553/obesity-new-insights-into-bat-activity
#5
Alan Morris
No abstract text is available yet for this article.
August 11, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28799552/thyroid-function-thyroid-hypofunction-in-pregnancy
#6
Claire Greenhill
No abstract text is available yet for this article.
August 11, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28776584/obesity-maternal-obesity-and-congenital-anomalies-risk-and-diagnosis
#7
Jodie M Dodd, Clare L Whitehead
No abstract text is available yet for this article.
August 4, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28776582/thyroid-disease-in-pregnancy-new-insights-in-diagnosis-and-clinical-management
#8
REVIEW
Tim I M Korevaar, Marco Medici, Theo J Visser, Robin P Peeters
Adequate thyroid hormone availability is important for an uncomplicated pregnancy and optimal fetal growth and development. Overt thyroid disease is associated with a wide range of adverse obstetric and child development outcomes. An increasing number of studies now indicate that milder forms of thyroid dysfunction are also associated with these adverse pregnancy outcomes. The definitions of both overt and subclinical thyroid dysfunction have changed considerably over the past few years, as new data indicate that the commonly used fixed upper limits of 2...
August 4, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28731035/growth-and-development-dwarfism-linked-to-hypertension-treatment
#9
David Holmes
No abstract text is available yet for this article.
July 21, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28731034/regulation-of-hepatic-glucose-metabolism-in-health-and-disease
#10
REVIEW
Max C Petersen, Daniel F Vatner, Gerald I Shulman
The liver is crucial for the maintenance of normal glucose homeostasis - it produces glucose during fasting and stores glucose postprandially. However, these hepatic processes are dysregulated in type 1 and type 2 diabetes mellitus, and this imbalance contributes to hyperglycaemia in the fasted and postprandial states. Net hepatic glucose production is the summation of glucose fluxes from gluconeogenesis, glycogenolysis, glycogen synthesis, glycolysis and other pathways. In this Review, we discuss the in vivo regulation of these hepatic glucose fluxes...
July 21, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28707681/liver-paradigm-shift-in-the-immunopathogenesis-of-nafld
#11
David Holmes
No abstract text is available yet for this article.
July 14, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28707680/targeted-therapies-lenvatinib-selects-survival-benefit
#12
Lisa Hutchinson
No abstract text is available yet for this article.
July 14, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28707679/anaplastic-thyroid-carcinoma-from-clinicopathology-to-genetics-and-advanced-therapies
#13
REVIEW
Eleonora Molinaro, Cristina Romei, Agnese Biagini, Elena Sabini, Laura Agate, Salvatore Mazzeo, Gabriele Materazzi, Stefano Sellari-Franceschini, Alessandro Ribechini, Liborio Torregrossa, Fulvio Basolo, Paolo Vitti, Rossella Elisei
Anaplastic thyroid carcinoma (ATC) is a rare malignancy, accounting for 1-2% of all thyroid cancers. Although rare, ATC accounts for the majority of deaths from thyroid carcinoma. ATC often originates in a pre-existing thyroid cancer lesion, as suggested by the simultaneous presence of areas of differentiated or poorly differentiated thyroid carcinoma. ATC is characterized by the accumulation of several oncogenic alterations, and studies have shown that an increased number of oncogenic alterations equates to an increased level of dedifferentiation and aggressiveness...
July 14, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28707678/cardiovascular-endocrinology-is-angptl3-the-next-pcsk9
#14
Kiran Musunuru, Sekar Kathiresan
No abstract text is available yet for this article.
July 14, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28707677/-omics-and-endocrine-disrupting-chemicals-new-paths-forward
#15
REVIEW
Carmen Messerlian, Rosie M Martinez, Russ Hauser, Andrea A Baccarelli
The emerging field of omics - large-scale data-rich biological measurements of the genome - provides new opportunities to advance and strengthen research into endocrine-disrupting chemicals (EDCs). Although some EDCs have been associated with adverse health effects in humans, our understanding of their impact remains incomplete. Progress in the field has been primarily limited by our inability to adequately estimate and characterize exposure and identify sensitive and measurable outcomes during windows of vulnerability...
July 14, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28707676/obesity-olfactory-senses-linked-to-metabolism
#16
Alan Morris
No abstract text is available yet for this article.
July 14, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28685768/obesity-gut-microbiome-and-serum-metabolome-changes
#17
Claire Greenhill
No abstract text is available yet for this article.
July 7, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28685767/type-1-diabetes-mellitus-is-a-heterogeneous-disease
#18
Mikael Knip
No abstract text is available yet for this article.
July 7, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28685766/gut-microbiota-link-between-the-gut-and-adipose-tissues
#19
Alan Morris
No abstract text is available yet for this article.
July 7, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28664920/fgf1-a-new-weapon-to-control-type-2-diabetes-mellitus
#20
REVIEW
Emanuel Gasser, Christopher P Moutos, Michael Downes, Ronald M Evans
A hypercaloric diet combined with a sedentary lifestyle is a major risk factor for the development of insulin resistance, type 2 diabetes mellitus (T2DM) and associated comorbidities. Standard treatment for T2DM begins with lifestyle modification, and includes oral medications and insulin therapy to compensate for progressive β-cell failure. However, current pharmaceutical options for T2DM are limited in that they do not maintain stable, durable glucose control without the need for treatment intensification...
June 30, 2017: Nature Reviews. Endocrinology
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