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Nature Reviews. Cardiology

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https://www.readbyqxmd.com/read/29789627/publisher-correction-exosome-based-therapy-to-repair-the-injured-heart
#1
Alexandra Le Bras
The article originally published online contained an error in the figure in which the scale bar was incorrectly associated with a value of 100 µm. This error has been corrected in the HTML and PDF versions of the article to associate the scale bar with the correct value of 1 mm.
May 22, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29789626/efficacy-of-cardiac-contractility-modulation-confirmed
#2
Irene Fernández-Ruiz
No abstract text is available yet for this article.
May 22, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29777181/genetic-variation-explains-residual-chd-risk-with-statin-therapy
#3
Alexandra Le Bras
No abstract text is available yet for this article.
May 17, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29777180/radial-artery-versus-saphenous-vein-grafts
#4
Alexandra Le Bras
No abstract text is available yet for this article.
May 17, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29777179/tannylated-proteins-target-the-heart
#5
Alexandra Le Bras
No abstract text is available yet for this article.
May 17, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29752454/assigning-matrix-metalloproteinase-roles-in-ischaemic-cardiac-remodelling
#6
REVIEW
Merry L Lindsey
Matrix metalloproteinases (MMPs) and their endogenous inhibitors have been studied in the myocardium for the past 2 decades. An incomplete knowledge base and experimental design issues with inhibitors have hampered attempts at translation, but clinical interest remains high because of strong associations between MMPs and outcomes after myocardial infarction (MI) as well as mechanistic studies showing MMP involvement at multiple stages of the MI wound-healing process. This Review focuses on how our understanding of MMPs has evolved from a one-dimensional early focus on measuring MMP activity, monitoring MMP:inhibitor ratios, and evaluating one MMP-substrate pair to the current use of systems biology approaches to integrate the whole MMP repertoire of roles in the left ventricular response to MI...
May 11, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29748594/reassessing-endothelial-to-mesenchymal-transition-in-cardiovascular-diseases
#7
REVIEW
Yan Li, Kathy O Lui, Bin Zhou
Endothelial cells and mesenchymal cells are two different cell types with distinct morphologies, phenotypes, functions, and gene profiles. Accumulating evidence, notably from lineage-tracing studies, indicates that the two cell types convert into each other during cardiovascular development and pathogenesis. During heart development, endothelial cells transdifferentiate into mesenchymal cells in the endocardial cushion through endothelial-to-mesenchymal transition (EndoMT), a process that is critical for the formation of cardiac valves...
May 10, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29748593/exosome-based-therapy-to-repair-the-injured-heart
#8
Alexandra Le Bras
No abstract text is available yet for this article.
May 10, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29743564/atherosclerosis-linked-to-faulty-dna-repair-in-vsmcs
#9
Caroline Barranco
No abstract text is available yet for this article.
May 9, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29743563/cell-therapy-trials-for-heart-regeneration-lessons-learned-and-future-directions
#10
REVIEW
Philippe Menasché
The effects of cell therapy on heart regeneration in patients with chronic cardiomyopathy have been assessed in several clinical trials. These trials can be categorized as those using noncardiac stem cells, including mesenchymal stem cells, and those using cardiac-committed cells, including KIT+ cardiac stem cells, cardiosphere-derived cells, and cardiovascular progenitor cells derived from embryonic stem cells. Although the safety of cell therapies has been consistently reported, their efficacy remains more elusive...
May 9, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29740152/treatment-of-pah-with-a-ppar%C3%AE-agonist
#11
Gregory B Lim
No abstract text is available yet for this article.
May 8, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29740151/ambulatory-versus-clinic-bp-values
#12
Gregory B Lim
No abstract text is available yet for this article.
May 8, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29717214/nanoimmunotherapy-targeting-cd40-traf6-signalling-to-reduce-atherosclerosis
#13
Gregory B Lim
No abstract text is available yet for this article.
May 1, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29713009/role-of-salt-intake-in-prevention-of-cardiovascular-disease-controversies-and-challenges
#14
REVIEW
Feng J He, Graham A MacGregor
Strong evidence indicates that reduction of salt intake lowers blood pressure and reduces the risk of cardiovascular disease (CVD). The WHO has set a global target of reducing the population salt intake from the current level of approximately 10 g daily to <5 g daily. This recommendation has been challenged by several studies, including cohort studies, which have suggested a J-shaped relationship between salt intake and CVD risk. However, these studies had severe methodological problems, such as reverse causality and measurement error due to assessment of salt intake by spot urine...
May 1, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29713011/pathophysiological-coronary-and-microcirculatory-flow-alterations-in-aortic-stenosis
#15
REVIEW
Michael Michail, Justin E Davies, James D Cameron, Kim H Parker, Adam J Brown
Regulation of coronary blood flow is maintained through a delicate balance of ventriculoarterial and neurohumoral mechanisms. The aortic valve is integral to the functions of these systems, and disease states that compromise aortic valve integrity have the potential to seriously disrupt coronary blood flow. Aortic stenosis (AS) is the most common cause of valvular heart disease requiring medical intervention, and the prevalence and associated socio-economic burden of AS are set to increase with population ageing...
April 30, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29713010/dynamics-of-fibroblast-activation-in-the-infarcted-heart
#16
Alexandra Le Bras
No abstract text is available yet for this article.
April 30, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29700402/selenoprotein-p-a-new-player-in-pah
#17
Irene Fernández-Ruiz
No abstract text is available yet for this article.
April 26, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29700401/fitness-ameliorates-genetic-risk-of-heart-disease
#18
Gregory B Lim
No abstract text is available yet for this article.
April 26, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29700400/young-women-have-worse-outcomes-after-stemi
#19
Gregory B Lim
No abstract text is available yet for this article.
April 26, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29700399/breast-cancer-therapy-and-cardiac-mortality
#20
Gregory B Lim
No abstract text is available yet for this article.
April 26, 2018: Nature Reviews. Cardiology
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