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Nature Reviews. Cardiology

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https://www.readbyqxmd.com/read/30002481/dual-therapy-stent-shows-promise
#1
Irene Fernández-Ruiz
No abstract text is available yet for this article.
July 12, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29985453/detection-of-atrial-fibrillation-using-a-smartwatch
#2
Ki H Chon, David D McManus
No abstract text is available yet for this article.
July 9, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29980782/aaa-to-screen-or-not-to-screen
#3
Alexandra Le Bras
No abstract text is available yet for this article.
July 6, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29973710/the-complex-molecular-genetics-of-familial-hypercholesterolaemia
#4
REVIEW
Amanda J Berberich, Robert A Hegele
Familial hypercholesterolaemia is the most commonly encountered genetic condition that predisposes individuals to premature cardiovascular disease. Nevertheless, most patients are undiagnosed, and treatment is often suboptimal even when the diagnosis seems certain. Advances in molecular technologies are reshaping our understanding of this condition, including revision upwards of the population prevalence. Furthermore, the underlying pathophysiological complexity has been exposed by the range of causative genetic loci, breadth of types and classes of rare disease-causing variants, and polygenic basis of the phenotype in many patients...
July 4, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29973709/aspirin-free-strategies-in-cardiovascular-disease-and-cardioembolic-stroke-prevention
#5
REVIEW
Davide Capodanno, Roxana Mehran, Marco Valgimigli, Usman Baber, Stephan Windecker, Pascal Vranckx, George Dangas, Fabiana Rollini, Takeshi Kimura, Jean-Philippe Collet, C Michael Gibson, Philippe Gabriel Steg, Renato D Lopes, Hyeon-Cheol Gwon, Robert F Storey, Francesco Franchi, Deepak L Bhatt, Patrick W Serruys, Dominick J Angiolillo
In patients with manifestations of cardiovascular disease, acetylsalicylic acid (popularly known as aspirin) has been the mainstay of treatment for decades owing to its capacity to reduce the risk of ischaemic events. Accordingly, novel antithrombotic therapies have been traditionally tested on a background of acetylsalicylic acid therapy. Although the adjunctive use of such antithrombotic therapies can potentially further reduce the risk of ischaemic events, these agents are also inevitably associated with an increased risk of bleeding...
July 4, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29955174/targeting-the-cytoskeleton-in-heart-failure
#6
Irene Fernández-Ruiz
No abstract text is available yet for this article.
June 28, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29950578/the-epicardium-as-a-hub-for-heart-regeneration
#7
REVIEW
Jingli Cao, Kenneth D Poss
After decades of directed research, no effective regenerative therapy is currently available to repair the injured human heart. The epicardium, a layer of mesothelial tissue that envelops the heart in all vertebrates, has emerged as a new player in cardiac repair and regeneration. The epicardium is essential for muscle regeneration in the zebrafish model of innate heart regeneration, and the epicardium also participates in fibrotic responses in mammalian hearts. This structure serves as a source of crucial cells, such as vascular smooth muscle cells, pericytes, and fibroblasts, during heart development and repair...
June 27, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29941964/erectile-dysfunction-predicts-cvd-events
#8
Gregory B Lim
No abstract text is available yet for this article.
June 25, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29941963/lima1-variant-influences-cholesterol-absorption
#9
Gregory B Lim
No abstract text is available yet for this article.
June 25, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29941962/distinct-macrophage-subsets-in-the-human-heart
#10
Gregory B Lim
No abstract text is available yet for this article.
June 25, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29934578/inflammatory-and-atherogenic-effects-of-oxidized-phospholipids
#11
Gregory B Lim
No abstract text is available yet for this article.
June 22, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29930268/chronotherapy-for-atherosclerosis
#12
Alexandra Le Bras
No abstract text is available yet for this article.
June 21, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29921936/reply-to-salt-intake-cardiovascular-disease-and-physiology
#13
LETTER
Feng J He, Graham A MacGregor
No abstract text is available yet for this article.
June 19, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29921935/sodium-intake-cardiovascular-disease-and-physiology
#14
LETTER
Simon N Thornton
No abstract text is available yet for this article.
June 19, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29915254/metabolic-remodelling-in-heart-failure
#15
REVIEW
Edoardo Bertero, Christoph Maack
The heart consumes large amounts of energy in the form of ATP that is continuously replenished by oxidative phosphorylation in mitochondria and, to a lesser extent, by glycolysis. To adapt the ATP supply efficiently to the constantly varying demand of cardiac myocytes, a complex network of enzymatic and signalling pathways controls the metabolic flux of substrates towards their oxidation in mitochondria. In patients with heart failure, derangements of substrate utilization and intermediate metabolism, an energetic deficit, and oxidative stress are thought to underlie contractile dysfunction and the progression of the disease...
June 18, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29891969/inflammasome-activation-in-af
#16
Irene Fernández-Ruiz
No abstract text is available yet for this article.
June 11, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29875439/transcriptional-regulation-of-the-cardiac-conduction-system
#17
REVIEW
Vincent W W van Eif, Harsha D Devalla, Gerard J J Boink, Vincent M Christoffels
The rate and rhythm of heart muscle contractions are coordinated by the cardiac conduction system (CCS), a generic term for a collection of different specialized muscular tissues within the heart. The CCS components initiate the electrical impulse at the sinoatrial node, propagate it from atria to ventricles via the atrioventricular node and bundle branches, and distribute it to the ventricular muscle mass via the Purkinje fibre network. The CCS thereby controls the rate and rhythm of alternating contractions of the atria and ventricles...
June 6, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29875438/renewed-hopes-for-renal-denervation-in-hypertension
#18
Irene Fernández-Ruiz
No abstract text is available yet for this article.
June 6, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29872165/therapeutic-approaches-for-cardiac-regeneration-and-repair
#19
REVIEW
Hisayuki Hashimoto, Eric N Olson, Rhonda Bassel-Duby
Ischaemic heart disease is a leading cause of death worldwide. Injury to the heart is followed by loss of the damaged cardiomyocytes, which are replaced with fibrotic scar tissue. Depletion of cardiomyocytes results in decreased cardiac contraction, which leads to pathological cardiac dilatation, additional cardiomyocyte loss, and mechanical dysfunction, culminating in heart failure. This sequential reaction is defined as cardiac remodelling. Many therapies have focused on preventing the progressive process of cardiac remodelling to heart failure...
June 5, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29872164/enduring-fame-of-ffr-guided-pci
#20
Gregory B Lim
No abstract text is available yet for this article.
June 5, 2018: Nature Reviews. Cardiology
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