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Nature Reviews. Cardiology

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https://www.readbyqxmd.com/read/30214021/cardiovascular-safety-of-lorcaserin
#1
Gregory B Lim
No abstract text is available yet for this article.
September 13, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30214020/no-benefit-of-n-3-fatty-acid-supplements-in-diabetes
#2
Gregory B Lim
No abstract text is available yet for this article.
September 13, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30214019/tafamidis-a-new-treatment-for-attr-cardiomyopathy
#3
Alexandra Le Bras
No abstract text is available yet for this article.
September 13, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30209355/nanoimmunotherapy-to-treat-ischaemic-heart-disease
#4
REVIEW
Raphaël Duivenvoorden, Max L Senders, Mandy M T van Leent, Carlos Pérez-Medina, Matthias Nahrendorf, Zahi A Fayad, Willem J M Mulder
Atherosclerosis is a chronic disease of the large arteries and the underlying cause of myocardial infarction and stroke. Atherosclerosis is driven by cholesterol accumulation and subsequent inflammation in the vessel wall. Despite the clinical successes of lipid-lowering treatments, atherosclerosis remains one of the major threats to human health worldwide. Over the past 20 years, insights into cardiovascular immunopathology have provided a plethora of new potential therapeutic targets to reduce the risk of atherosclerosis and have shifted the therapeutic focus from lipids to inflammation...
September 12, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30209354/using-reconditioned-pacemakers-to-treat-bradycardia-in-africa
#5
Kevin Wunderly, Zaheer Yousef, Aimé Bonny, Kevin J Weatherwax, Balasundaram Lavan, Craig Allmendinger, Brad Wasserman, George Samson, Sheldon Davis, George Nel, James Russell, Constantine Akwanalo, Mahmoud U Sani, Ashely Chin, Olujimi A Ajijola, Bongani M Mayosi, Kim A Eagle, Thomas C Crawford
No abstract text is available yet for this article.
September 12, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30202121/no-benefit-of-mitraclip-for-secondary-mitral-regurgitation-in-heart-failure
#6
Irene Fernández-Ruiz
No abstract text is available yet for this article.
September 10, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30194400/early-invasive-assessment-of-nste-acs
#7
Gregory B Lim
No abstract text is available yet for this article.
September 7, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30194399/no-benefit-of-rivaroxaban-in-hf-with-sinus-rhythm
#8
Gregory B Lim
No abstract text is available yet for this article.
September 7, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30194398/rivaroxaban-for-prevention-of-vte
#9
Gregory B Lim
No abstract text is available yet for this article.
September 7, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30190531/hallmarks-of-cardiac-regeneration
#10
Alessandro Bertero, Charles E Murry
No abstract text is available yet for this article.
September 6, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30181596/the-interstitium-in-cardiac-repair-role-of-the-immune-stromal-cell-interplay
#11
REVIEW
Elvira Forte, Milena Bastos Furtado, Nadia Rosenthal
Cardiac regeneration, that is, restoration of the original structure and function in a damaged heart, differs from tissue repair, in which collagen deposition and scar formation often lead to functional impairment. In both scenarios, the early-onset inflammatory response is essential to clear damaged cardiac cells and initiate organ repair, but the quality and extent of the immune response vary. Immune cells embedded in the damaged heart tissue sense and modulate inflammation through a dynamic interplay with stromal cells in the cardiac interstitium, which either leads to recapitulation of cardiac morphology by rebuilding functional scaffolds to support muscle regrowth in regenerative organisms or fails to resolve the inflammatory response and produces fibrotic scar tissue in adult mammals...
September 4, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30177752/targeting-mitochondria-for-cardiovascular-disorders-therapeutic-potential-and-obstacles
#12
REVIEW
Massimo Bonora, Mariusz R Wieckowski, David A Sinclair, Guido Kroemer, Paolo Pinton, Lorenzo Galluzzi
A large body of evidence indicates that mitochondrial dysfunction has a major role in the pathogenesis of multiple cardiovascular disorders. Over the past 2 decades, extraordinary efforts have been focused on the development of agents that specifically target mitochondria for the treatment of cardiovascular disease. Despite such an intensive wave of investigation, no drugs specifically conceived to modulate mitochondrial functions are currently available for the clinical management of cardiovascular disease...
September 3, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30140053/targeting-the-gut-to-protect-the-heart
#13
Alexandra Le Bras
No abstract text is available yet for this article.
August 23, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30115967/exercise-benefits-in-cardiovascular-disease-beyond-attenuation-of-traditional-risk-factors
#14
REVIEW
Carmen Fiuza-Luces, Alejandro Santos-Lozano, Michael Joyner, Pedro Carrera-Bastos, Oscar Picazo, José L Zugaza, Mikel Izquierdo, Luis M Ruilope, Alejandro Lucia
Despite strong scientific evidence supporting the benefits of regular exercise for the prevention and management of cardiovascular disease (CVD), physical inactivity is highly prevalent worldwide. In addition to merely changing well-known risk factors for systemic CVD, regular exercise can also improve cardiovascular health through non-traditional mechanisms. Understanding the pathways through which exercise influences different physiological systems is important and might yield new therapeutic strategies to target pathophysiological mechanisms in CVD...
August 16, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30111784/the-hippo-pathway-in-the-heart-pivotal-roles-in-development-disease-and-regeneration
#15
REVIEW
Jun Wang, Shijie Liu, Todd Heallen, James F Martin
The Hippo-YAP (Yes-associated protein) pathway is an evolutionarily and functionally conserved regulator of organ size and growth with crucial roles in cell proliferation, apoptosis, and differentiation. This pathway has great potential for therapeutic manipulation in different disease states and to promote organ regeneration. In this Review, we summarize findings from the past decade revealing the function and regulation of the Hippo-YAP pathway in cardiac development, growth, homeostasis, disease, and regeneration...
August 15, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30054573/whole-genome-sequencing-for-hcm-screening
#16
Irene Fernandez-Ruiz
No abstract text is available yet for this article.
July 27, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30054572/ldl-quality-influences-cad-progression
#17
Irene Fernandez-Ruiz
No abstract text is available yet for this article.
July 27, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30054571/lower-stroke-rates-with-pci-than-with-surgery
#18
Irene Fernandez-Ruiz
No abstract text is available yet for this article.
July 27, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30050095/unravelling-the-atheroprotective-mechanisms-of-ldl-immunization
#19
Irene Fernández-Ruiz
No abstract text is available yet for this article.
July 26, 2018: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/30042432/cardiac-lymphatics-mediate-the-resolution-of-inflammation
#20
Alexandra Le Bras
No abstract text is available yet for this article.
July 24, 2018: Nature Reviews. Cardiology
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