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Nature Reviews. Cardiology

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https://www.readbyqxmd.com/read/28102234/heart-failure-recombinant-neuregulin-for-hf-treatment
#1
Dario Ummarino
No abstract text is available yet for this article.
January 19, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28102233/arrhythmias-optogenetic-control-of-cardiac-rhythm
#2
Dario Ummarino
No abstract text is available yet for this article.
January 19, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28102232/aetiology-and-management-of-hereditary-aortopathy
#3
REVIEW
Aline Verstraeten, Ilse Luyckx, Bart Loeys
Aortic aneurysms are a major health problem because they account for 1-2% of all deaths in the Western population. Although abdominal aortic aneurysms (AAAs) are more prevalent than thoracic aortic aneurysms (TAAs), TAAs have been more exhaustively studied over the past 2 decades because they have a higher heritability and affect younger individuals. Gene identification in both syndromic and nonsyndromic TAA is proceeding at a rapid pace and has already pinpointed >20 genes associated with familial TAA risk...
January 19, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28102231/cell-therapy-autologous-cardiac-stem-cells-for-congenital-hf
#4
Dario Ummarino
No abstract text is available yet for this article.
January 19, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28079111/killing-the-old-cell-senescence-in-atherosclerosis
#5
Martin R Bennett, Murray C H Clarke
No abstract text is available yet for this article.
January 12, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28079110/left-ventricular-noncompaction-cardiomyopathy-cardiac-neuromuscular-and-genetic-factors
#6
REVIEW
Josef Finsterer, Claudia Stöllberger, Jeffrey A Towbin
Left ventricular hypertrabeculation (LVHT) or noncompaction is a myocardial abnormality of unknown aetiology, frequently associated with monogenic disorders, particularly neuromuscular disorders, or with chromosomal defects. LVHT is diagnosed usually by echocardiography by the presence of a bilayered myocardium consisting of a thick, spongy, noncompacted endocardial layer and a thin, compacted, epicardial layer. The pathogenesis of LVHT is unsolved, and the diagnostic criteria, prognosis, and optimal treatment of patients with LVHT are under debate...
January 12, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28054580/nlrp3-inflammasome-common-nexus-between-depression-and-cardiovascular-diseases
#7
Elísabet Alcocer-Gómez, Mario D Cordero
No abstract text is available yet for this article.
January 5, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28054579/device-therapy-optimization-of-crt-with-novel-contractility-sensor
#8
Karina Huynh
No abstract text is available yet for this article.
January 5, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28054578/reply-the-complexity-of-substance-p-mediated-mast-cell-activation
#9
Guo-Ping Shi, Ilze Bot, Petri T Kovanen
No abstract text is available yet for this article.
January 5, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28054577/genetics-of-chd-in-2016-common-and-rare-genetic-variants-and-risk-of-chd
#10
Daniel I Swerdlow, Steve E Humphries
No abstract text is available yet for this article.
January 5, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28054576/acute-coronary-syndromes-in-2016-assessing-strategies-to-improve-patient-management
#11
Ron Waksman
No abstract text is available yet for this article.
January 5, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28054575/reply-nlrp3-inflammasome-as-a-mechanism-linking-depression-and-cardiovascular-diseases
#12
Robert M Carney, Kenneth E Freedland
No abstract text is available yet for this article.
January 5, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28054574/implications-of-mrgprx2-in-human-and-experimental-cardiometabolic-diseases
#13
Ehsan Azimi, Ethan A Lerner
No abstract text is available yet for this article.
January 5, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28054573/inflammation-nsaids-and-cardiovascular-risk-in-arthritis
#14
Miguel A González-Gay, Carlos González-Juanatey
No abstract text is available yet for this article.
January 5, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28004807/expert-consensus-document-mitochondrial-function-as-a-therapeutic-target-in-heart-failure
#15
David A Brown, Justin B Perry, Mitchell E Allen, Hani N Sabbah, Brian L Stauffer, Saame Raza Shaikh, John G F Cleland, Wilson S Colucci, Javed Butler, Adriaan A Voors, Stefan D Anker, Bertram Pitt, Burkert Pieske, Gerasimos Filippatos, Stephen J Greene, Mihai Gheorghiade
Heart failure is a pressing worldwide public-health problem with millions of patients having worsening heart failure. Despite all the available therapies, the condition carries a very poor prognosis. Existing therapies provide symptomatic and clinical benefit, but do not fully address molecular abnormalities that occur in cardiomyocytes. This shortcoming is particularly important given that most patients with heart failure have viable dysfunctional myocardium, in which an improvement or normalization of function might be possible...
December 22, 2016: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/27974810/genetics-hmgcr-and-pcsk9-variants-and-cardiovascular-risk
#16
Gregory B Lim
No abstract text is available yet for this article.
December 15, 2016: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/27974809/arrhythmias-weight-loss-and-reduced-risk-of-atrial-fibrillation
#17
Gregory B Lim
No abstract text is available yet for this article.
December 15, 2016: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/27974808/heart-failure-phase-ii-trial-results-of-omecamtiv-mecarbil
#18
Gregory B Lim
No abstract text is available yet for this article.
December 15, 2016: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/27974807/long-term-neprilysin-inhibition-implications-for-arnis
#19
REVIEW
Duncan J Campbell
Neprilysin has a major role in both the generation and degradation of bioactive peptides. LCZ696 (valsartan/sacubitril, Entresto), the first of the new ARNI (dual-acting angiotensin-receptor-neprilysin inhibitor) drug class, contains equimolar amounts of valsartan, an angiotensin-receptor blocker, and sacubitril, a prodrug for the neprilysin inhibitor LBQ657. LCZ696 reduced blood pressure more than valsartan alone in patients with hypertension. In the PARADIGM-HF study, LCZ696 was superior to the angiotensin-converting enzyme inhibitor enalapril for the treatment of heart failure with reduced ejection fraction, and LCZ696 was approved by the FDA for this purpose in 2015...
December 15, 2016: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/27929027/vascular-diseases-shear-thinning-biomaterial-for-endovascular-embolization
#20
Karina Huynh
No abstract text is available yet for this article.
December 8, 2016: Nature Reviews. Cardiology
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