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Nature Reviews. Neurology

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https://www.readbyqxmd.com/read/28643808/parkinson-disease-deep-brain-stimulation-making-the-right-connections
#1
Charlotte Ridler
No abstract text is available yet for this article.
June 23, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28643807/infectious-disease-musashi-1-protein-could-mediate-the-effects-of-zika-virus-on-brain-development
#2
Heather Wood
No abstract text is available yet for this article.
June 23, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28643806/dementia-persistent-pain-might-be-a-harbinger-of-cognitive-decline-in-older-people
#3
Heather Wood
No abstract text is available yet for this article.
June 23, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28643805/parkinson-disease-plasma-%C3%AE-synuclein-a-potential-marker-of-cognitive-impairment-in-parkinson-disease
#4
Heather Wood
No abstract text is available yet for this article.
June 23, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28621771/repeat-expansion-disorders-new-evidence-for-rna-gelation-in-repeat-expansion-disorders
#5
Heather Wood
No abstract text is available yet for this article.
June 16, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28621768/imaging-and-fluid-biomarkers-in-frontotemporal-dementia
#6
REVIEW
Lieke H Meeter, Laura Donker Kaat, Jonathan D Rohrer, John C van Swieten
Frontotemporal dementia (FTD), the second most common type of presenile dementia, is a heterogeneous neurodegenerative disease characterized by progressive behavioural and/or language problems, and includes a range of clinical, genetic and pathological subtypes. The diagnostic process is hampered by this heterogeneity, and correct diagnosis is becoming increasingly important to enable future clinical trials of disease-modifying treatments. Reliable biomarkers will enable us to better discriminate between FTD and other forms of dementia and to predict disease progression in the clinical setting...
June 16, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28621767/neuroimmunology-complement-is-no-bystander-in-cns-degeneration
#7
Ian Fyfe
No abstract text is available yet for this article.
June 16, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28621766/autologous-haematopoietic-stem-cell-transplantation-for-treatment-of-multiple-sclerosis
#8
REVIEW
Paolo A Muraro, Roland Martin, Giovanni Luigi Mancardi, Richard Nicholas, Maria Pia Sormani, Riccardo Saccardi
Autologous haematopoietic stem cell transplantation (AHSCT) is a multistep procedure that enables destruction of the immune system and its reconstitution from haematopoietic stem cells. Originally developed for the treatment of haematological malignancies, the procedure has been adapted for the treatment of severe immune-mediated disorders. Results from ∼20 years of research make a compelling case for selective use of AHSCT in patients with highly active multiple sclerosis (MS), and for controlled trials...
June 16, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28621764/neuroimmunology-b-cells-and-variant-baff-in-autoimmune-disease
#9
Manuel Comabella
No abstract text is available yet for this article.
June 16, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28621770/epilepsy-a-new-guideline-on-sudden-unexpected-death-in-epilepsy
#10
Daniel Friedman
No abstract text is available yet for this article.
June 9, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28621769/alzheimer-disease-sniffing-out-a-marker-of-early-alzheimer-disease
#11
Ian Fyfe
No abstract text is available yet for this article.
June 9, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28621765/epilepsy-cannabidiol-reduces-seizure-frequency-in-dravet-syndrome
#12
Charlotte Ridler
No abstract text is available yet for this article.
June 9, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28574061/stroke-long-term-outcome-of-endovascular-therapy-for-ischaemic-stroke
#13
Charlotte Zerna, Mayank Goyal
No abstract text is available yet for this article.
June 2, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28574060/neurodevelopmental-disorders-metformin-a-therapeutic-option-for-fragile-x-syndrome
#14
Heather Wood
No abstract text is available yet for this article.
June 2, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28548108/drugging-the-pain-epigenome
#15
REVIEW
Ellen Niederberger, Eduard Resch, Michael J Parnham, Gerd Geisslinger
More than 20% of adults worldwide experience different types of chronic pain, which are frequently associated with several comorbidities and a decrease in quality of life. Several approved painkillers are available, but current analgesics are often hampered by insufficient efficacy and/or severe adverse effects. Consequently, novel strategies for safe, highly efficacious treatments are highly desirable, particularly for chronic pain. Epigenetic mechanisms such as DNA methylation, histone modifications and microRNAs (miRNAs) strongly affect the regulation of gene expression, potentially for long periods over years or even generations, and have been associated with pathophysiological pain...
May 26, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28548107/current-controversies-in-brain-death-determination
#16
REVIEW
Ariane Lewis, David Greer
Although the concept of brain death is accepted by the majority of physicians, lawyers, ethicists and society at large, controversies about determination of death by neurological criteria persist, and often reach the public eye. In this article, we examine four prominent controversial brain death cases from 2013-2016. We review current controversies, including protocol variability, recognition of the American Academy of Neurology (AAN) criteria for brain death as an accepted medical standard, and management of objections to discontinuation of organ support after determination of brain death...
May 26, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28548106/cerebrovascular-malformations-microbiota-promotes-cerebral-cavernous-malformations
#17
Charlotte Ridler
No abstract text is available yet for this article.
May 26, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28548105/alzheimer-disease-peripheral-a%C3%AE-clearance-a-therapeutic-strategy-for-ad
#18
Heather Wood
No abstract text is available yet for this article.
May 26, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28524175/modulators-of-microglial-activation-and-polarization-after-intracerebral-haemorrhage
#19
REVIEW
Xi Lan, Xiaoning Han, Qian Li, Qing-Wu Yang, Jian Wang
Intracerebral haemorrhage (ICH) is the most lethal subtype of stroke but currently lacks effective treatment. Microglia are among the first non-neuronal cells on the scene during the innate immune response to ICH. Microglia respond to acute brain injury by becoming activated and developing classic M1-like (proinflammatory) or alternative M2-like (anti-inflammatory) phenotypes. This polarization implies as yet unrecognized actions of microglia in ICH pathology and recovery, perhaps involving microglial production of proinflammatory or anti-inflammatory cytokines and chemokines...
May 19, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28524174/dementia-imaging-signatures-identified-for-dementia-subtypes
#20
Ian Fyfe
No abstract text is available yet for this article.
May 19, 2017: Nature Reviews. Neurology
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