journal
MENU ▼
Read by QxMD icon Read
search

Nature Reviews. Neurology

journal
https://www.readbyqxmd.com/read/29777184/genotype-phenotype-links-in-frontotemporal-lobar-degeneration
#1
REVIEW
Sara Van Mossevelde, Sebastiaan Engelborghs, Julie van der Zee, Christine Van Broeckhoven
Frontotemporal lobar degeneration (FTLD) represents a group of neurodegenerative brain diseases with highly heterogeneous clinical, neuropathological and genetic characteristics. This high degree of heterogeneity results from the presence of several different underlying molecular disease processes; consequently, it is unlikely that all patients with FTLD will benefit from a single therapy. Therapeutic strategies for FTLD are currently being explored, and tools are urgently needed that enable the selection of patients who are the most likely to benefit from a particular therapy...
May 18, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29769699/a-stocked-toolbox-for-understanding-the-role-of-astrocytes-in-disease
#2
REVIEW
Akshata Almad, Nicholas J Maragakis
Our understanding of astrocytes and their role in neurological diseases has increased considerably over the past two decades as the diverse roles of these cells have become recognized. Our evolving understanding of these cells suggests that they are more than support cells for neurons and that they play important roles in CNS homeostasis under normal conditions, in neuroprotection and in disease exacerbation. These multiple functions make them excellent candidates for targeted therapies to treat neurological disorders...
May 16, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29765132/stars-of-neurology-meet-at-aan-2018
#3
Heather Wood
No abstract text is available yet for this article.
May 15, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29765131/neuroimaging-model-predicts-time-of-symptom-onset-in-sporadic-ad
#4
Charlotte Ridler
No abstract text is available yet for this article.
May 15, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29713016/amyloid-%C3%AE-a-reflection-of-risk-or-a-preclinical-marker
#5
Clifford R Jack, Prashanthi Vemuri
No abstract text is available yet for this article.
April 30, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29695800/crispr-expands-insight-into-the-mechanisms-of-als-and-ftd
#6
Sarah Pickles, Leonard Petrucelli
No abstract text is available yet for this article.
April 25, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29691492/retinal-implants-show-promise-in-macular-degeneration
#7
Heather Wood
No abstract text is available yet for this article.
April 24, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29691491/designer-exosomes-alleviate-neurotoxicity
#8
Charlotte Ridler
No abstract text is available yet for this article.
April 24, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29691490/cgrp-as-the-target-of-new-migraine-therapies-successful-translation-from-bench-to-clinic
#9
REVIEW
Lars Edvinsson, Kristian Agmund Haanes, Karin Warfvinge, Diana N Krause
Treatment of migraine is on the cusp of a new era with the development of drugs that target the trigeminal sensory neuropeptide calcitonin gene-related peptide (CGRP) or its receptor. Several of these drugs are expected to receive approval for use in migraine headache in 2018 and 2019. CGRP-related therapies offer considerable improvements over existing drugs as they are the first to be designed specifically to act on the trigeminal pain system, they are more specific and they seem to have few or no adverse effects...
April 24, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29674752/protecting-the-ischaemic-penumbra-as-an-adjunct-to-thrombectomy-for-acute-stroke
#10
REVIEW
Jean-Claude Baron
After ischaemic stroke, brain damage can be curtailed by rescuing the 'ischaemic penumbra' - that is, the severely hypoperfused, at-risk but not yet infarcted tissue. Current evidence-based treatments involve restoration of blood flow so as to salvage the penumbra before it evolves into irreversibly damaged tissue, termed the 'core'. Intravenous thrombolysis (IVT) can salvage the penumbra if given within 4.5 h after stroke onset; however, the early recanalization rate is only ~30%. Direct removal of the occluding clot by mechanical thrombectomy considerably improves outcomes over IVT alone, but despite early recanalization in > 80% of cases, ~50% of patients who receive this treatment do not enjoy functional independence, usually because the core is already too large at the time of recanalization...
April 19, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29666425/prediction-of-cognitive-decline-in-pd
#11
Ian Fyfe
No abstract text is available yet for this article.
April 17, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29623949/teleneurology-and-mobile-technologies-the-future-of-neurological-care
#12
REVIEW
E Ray Dorsey, Alistair M Glidden, Melissa R Holloway, Gretchen L Birbeck, Lee H Schwamm
Neurological disorders are the leading cause of global disability. However, for most people around the world, current neurological care is poor. In low-income countries, most individuals lack access to proper neurological care, and in high-income countries, distance and disability limit access. With the global proliferation of smartphones, teleneurology - the use of technology to provide neurological care and education remotely - has the potential to improve and increase access to care for billions of people...
April 6, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29622780/new-biomarkers-of-postoperative-neurocognitive-disorders
#13
Zhongcong Xie, Yuan Shen
No abstract text is available yet for this article.
April 5, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29611539/corrigendum-pet-imaging-of-the-neurovascular-interface-in-cerebrovascular-disease
#14
Nicholas R Evans, Jason M Tarkin, John R Buscombe, Hugh S Markus, James H F Rudd, Elizabeth A Warburton
This corrects the article DOI: 10.1038/nrneurol.2017.129.
April 3, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29611538/neuroimmunology-are-naturally-occurring-anti-nmdar-autoantibodies-pathogenic
#15
Keiko Tanaka
No abstract text is available yet for this article.
April 3, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29611537/stroke-an-alarmin-inflammatory-response-after-stroke
#16
Heather Wood
No abstract text is available yet for this article.
April 3, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29569626/epilepsy-timely-treatment-of-refractory-convulsive-status-epilepticus
#17
Alberto Verrotti, Chiara Mazzocchetti
No abstract text is available yet for this article.
March 23, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29569625/epilepsy-a-role-for-expanded-dna-repeats-in-familial-epilepsy
#18
Heather Wood
No abstract text is available yet for this article.
March 23, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29569624/physiological-changes-in-neurodegeneration-mechanistic-insights-and-clinical-utility
#19
REVIEW
Rebekah M Ahmed, Yazi D Ke, Steve Vucic, Lars M Ittner, William Seeley, John R Hodges, Olivier Piguet, Glenda Halliday, Matthew C Kiernan
The effects of neurodegenerative syndromes extend beyond cognitive function to involve key physiological processes, including eating and metabolism, autonomic nervous system function, sleep, and motor function. Changes in these physiological processes are present in several conditions, including frontotemporal dementia, amyotrophic lateral sclerosis, Alzheimer disease and the parkinsonian plus conditions. Key neural structures that mediate physiological changes across these conditions include neuroendocrine and hypothalamic pathways, reward pathways, motor systems and the autonomic nervous system...
March 23, 2018: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29569623/alzheimer-disease-epigenetics-links-ageing-with-alzheimer-disease
#20
Ian Fyfe
No abstract text is available yet for this article.
March 23, 2018: Nature Reviews. Neurology
journal
journal
42294
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"