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Nature Reviews. Neurology

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https://www.readbyqxmd.com/read/27909308/in-the-news
#1
Hemi Malkki
No abstract text is available yet for this article.
December 2, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27909307/motor-neuron-disease-brain-computer-interface-unlocks-the-mind-of-a-patient-with-als
#2
Heather Wood
No abstract text is available yet for this article.
December 2, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27886203/stroke-ct-identifies-patients-in-stroke-treatment-window
#3
Ian Fyfe
No abstract text is available yet for this article.
November 25, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27886202/multiple-sclerosis-new-imaging-marker-of-brain-leukocyte-infiltration
#4
Ian Fyfe
No abstract text is available yet for this article.
November 25, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27886201/cryptococcal-meningitis-epidemiology-immunology-diagnosis-and-therapy
#5
REVIEW
Peter R Williamson, Joseph N Jarvis, Anil A Panackal, Matthew C Fisher, Síle F Molloy, Angela Loyse, Thomas S Harrison
HIV-associated cryptococcal meningitis is by far the most common cause of adult meningitis in many areas of the world that have high HIV seroprevalence. In most areas in Sub-Saharan Africa, the incidence of cryptococcal meningitis is not decreasing despite availability of antiretroviral therapy, because of issues of adherence and retention in HIV care. In addition, cryptococcal meningitis in HIV-seronegative individuals is a substantial problem: the risk of cryptococcal infection is increased in transplant recipients and other individuals with defects in cell-mediated immunity, and cryptococcosis is also reported in the apparently immunocompetent...
November 25, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27857124/neuroinflammation-using-big-data-to-inform-clinical-practice
#6
REVIEW
Calliope A Dendrou, Gil McVean, Lars Fugger
Neuroinflammation is emerging as a central process in many neurological conditions, either as a causative factor or as a secondary response to nervous system insult. Understanding the causes and consequences of neuroinflammation could, therefore, provide insight that is needed to improve therapeutic interventions across many diseases. However, the complexity of the pathways involved necessitates the use of high-throughput approaches to extensively interrogate the process, and appropriate strategies to translate the data generated into clinical benefit...
November 18, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27857123/low-grade-epilepsy-associated-neuroepithelial-tumours-the-2016-who-classification
#7
REVIEW
Ingmar Blümcke, Eleonora Aronica, Albert Becker, David Capper, Roland Coras, Mrinalini Honavar, Thomas S Jacques, Katja Kobow, Hajime Miyata, Angelika Mühlebner, José Pimentel, Figen Söylemezoğlu, Maria Thom
Rapid developments in molecular genetic technology and research have swiftly advanced our understanding of neuro-oncology. As a consequence, the WHO invited their expert panels to revise the current classification system of brain tumours and to introduce, for the first time, a molecular genetic approach for selected tumour entities, thus setting a new gold standard in histopathology. The revised 5th edition of the 'blue book' was released in May 2016 and will have a major impact in stratifying diagnosis and treatment...
November 18, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27857122/eteplirsen-therapy-for-duchenne-muscular-dystrophy-skipping-to-the-front-of-the-line
#8
James J Dowling
No abstract text is available yet for this article.
November 18, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27857121/guillain-barr%C3%A3-syndrome-a-century-of-progress
#9
REVIEW
John A Goodfellow, Hugh J Willison
In 1916, Guillain, Barré and Strohl reported on two cases of acute flaccid paralysis with high cerebrospinal fluid protein levels and normal cell counts - novel findings that identified the disease we now know as Guillain-Barré syndrome (GBS). 100 years on, we have made great progress with the clinical and pathological characterization of GBS. Early clinicopathological and animal studies indicated that GBS was an immune-mediated demyelinating disorder, and that severe GBS could result in secondary axonal injury; the current treatments of plasma exchange and intravenous immunoglobulin, which were developed in the 1980s, are based on this premise...
November 18, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27857120/multiple-sclerosis-latitude-and-vitamin-d-influence-disease-course-in-multiple-sclerosis
#10
Heather Wood
No abstract text is available yet for this article.
November 18, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27857119/cerebrovascular-disease-lobar-cerebral-microbleeds-signal-early-cognitive-impairment
#11
Yusuke Yakushiji, David J Werring
No abstract text is available yet for this article.
November 18, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27834395/cns-infections-a-new-herpes-zoster-subunit-vaccine-for-older-adults
#12
Charlotte Warren-Gash, Judith Breuer
No abstract text is available yet for this article.
November 11, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27834394/the-central-vein-sign-and-its-clinical-evaluation-for-the-diagnosis-of-multiple-sclerosis-a-consensus-statement-from-the-north-american-imaging-in-multiple-sclerosis-cooperative
#13
Pascal Sati, Jiwon Oh, R Todd Constable, Nikos Evangelou, Charles R G Guttmann, Roland G Henry, Eric C Klawiter, Caterina Mainero, Luca Massacesi, Henry McFarland, Flavia Nelson, Daniel Ontaneda, Alexander Rauscher, William D Rooney, Amal P R Samaraweera, Russell T Shinohara, Raymond A Sobel, Andrew J Solomon, Constantina A Treaba, Jens Wuerfel, Robert Zivadinov, Nancy L Sicotte, Daniel Pelletier, Daniel S Reich
Over the past few years, MRI has become an indispensable tool for diagnosing multiple sclerosis (MS). However, the current MRI criteria for MS diagnosis have imperfect sensitivity and specificity. The central vein sign (CVS) has recently been proposed as a novel MRI biomarker to improve the accuracy and speed of MS diagnosis. Evidence indicates that the presence of the CVS in individual lesions can accurately differentiate MS from other diseases that mimic this condition. However, the predictive value of the CVS for the development of clinical MS in patients with suspected demyelinating disease is still unknown...
November 11, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27834393/neurodegenerative-disease-new-in-vivo-evidence-that-different-tau-strains-cause-different-diseases
#14
Ian Fyfe
No abstract text is available yet for this article.
November 11, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27811919/cerebrovascular-disorders-exercise-alleviates-vascular-cognitive-impairment
#15
Hemi Malkki
No abstract text is available yet for this article.
November 4, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27811918/multiple-sclerosis-coagulation-factors-could-mediate-neuroinflammation-in-multiple-sclerosis
#16
Hemi Malkki
No abstract text is available yet for this article.
November 4, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27811917/neuro-oncology-met-fusion-genes-implicated-as-treatment-target-in-paediatric-glioblastoma
#17
Hemi Malkki
No abstract text is available yet for this article.
November 4, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27811916/movement-disorders-novel-genetic-risk-variants-for-essential-tremor
#18
Hemi Malkki
No abstract text is available yet for this article.
November 4, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27808265/unruptured-intracranial-aneurysms-development-rupture-and-preventive-management
#19
REVIEW
Nima Etminan, Gabriel J Rinkel
Saccular unruptured intracranial aneurysms (UIAs) have a prevalence of 3% in the adult population, and are being increasingly detected because of improved quality and higher frequency of cranial imaging. Large amounts of data, providing varying levels of evidence, have been published on aneurysm development, progression and rupture, but less information is available on the risks and efficacy of preventive treatment. When deciding how to best manage UIAs, clinicians must consider the age and life expectancy of the patient, the estimated risk of rupture, the risk of complications attributed to preventive treatment, and the level of anxiety caused by the awareness of having an aneurysm...
November 3, 2016: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/27808264/alzheimer-disease-bace1-inhibition-could-block-csf-tau-increase
#20
Hemi Malkki
No abstract text is available yet for this article.
November 3, 2016: Nature Reviews. Neurology
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