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Nature Reviews. Neurology

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https://www.readbyqxmd.com/read/28799551/the-tension-between-early-diagnosis-and-misdiagnosis-of-multiple-sclerosis
#1
REVIEW
Andrew J Solomon, John R Corboy
No abstract text is available yet for this article.
August 11, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28799550/stroke-wearable-robot-aids-walking-after-stroke
#2
Charlotte Ridler
No abstract text is available yet for this article.
August 11, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28799549/neuroepidemiology-the-increasing-burden-of-mortality-from-neurological-diseases
#3
Julia Pakpoor, Michael Goldacre
No abstract text is available yet for this article.
August 11, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28776601/the-far-reaching-scope-of-neuroinflammation-after-traumatic-brain-injury
#4
Dennis W Simon, Mandy J McGeachy, Hülya Bayır, Robert S B Clark, David J Loane, Patrick M Kochanek
No abstract text is available yet for this article.
August 4, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28776600/neuroimmunology-new-targets-in-neuropsychiatric-lupus
#5
Ian Fyfe
No abstract text is available yet for this article.
August 4, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28776599/neuro-oncology-a-new-approach-to-ependymoma-subtyping
#6
Heather Wood
No abstract text is available yet for this article.
August 4, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28776598/dementia-prevention-hits-the-headlines-at-aaic17
#7
Charlotte Ridler
No abstract text is available yet for this article.
August 4, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28752858/neurodevelopmental-disorders-gene-therapy-for-mucopolysaccharidosis-shows-promise
#8
Heather Wood
No abstract text is available yet for this article.
July 28, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28752857/insights-into-the-mechanisms-of-deep-brain-stimulation
#9
REVIEW
Keyoumars Ashkan, Priya Rogers, Hagai Bergman, Ismail Ughratdar
Despite long-term and widespread use of deep brain stimulation (DBS) in a variety of neurological conditions, the underlying mechanisms of action have been elusive. Growing evidence suggests that DBS acts through multimodal mechanisms that are not limited to inhibition and excitation of basal ganglia circuits. DBS also seems to act over variable time spans - for example, the effects on tremor are immediate, whereas the effects on dystonia emerge over several weeks - suggesting that large networks are targeted...
July 28, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28752856/multiple-sclerosis-treatment-of-cognitive-impairment-in-secondary-progressive-ms
#10
Anthony Feinstein
No abstract text is available yet for this article.
July 28, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28731039/peripheral-neuropathies-long-term-opioid-therapy-in-neuropathy-benefit-or-harm
#11
Claudia Sommer
No abstract text is available yet for this article.
July 21, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28731038/alzheimer-disease-tau-pathology-in-atomic-detail
#12
Ian Fyfe
No abstract text is available yet for this article.
July 21, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28731037/dementia-skin-%C3%AE-synuclein-deposits-a-new-biomarker-for-dlb
#13
Heather Wood
No abstract text is available yet for this article.
July 21, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28731036/stroke-in-women-from-evidence-to-inequalities
#14
REVIEW
Charlotte Cordonnier, Nikola Sprigg, Else Charlotte Sandset, Aleksandra Pavlovic, Katharina S Sunnerhagen, Valeria Caso, Hanne Christensen
Stroke is the second largest cause of disability-adjusted life-years lost worldwide. The prevalence of stroke in women is predicted to rise rapidly, owing to the increasing average age of the global female population. Vascular risk factors differ between women and men in terms of prevalence, and evidence increasingly supports the clinical importance of sex differences in stroke. The influence of some risk factors for stroke - including diabetes mellitus and atrial fibrillation - are stronger in women, and hypertensive disorders of pregnancy also affect the risk of stroke decades after pregnancy...
July 21, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28708133/autoantibodies-in-chronic-inflammatory-neuropathies-diagnostic-and-therapeutic-implications
#15
REVIEW
Luis Querol, Jérôme Devaux, Ricard Rojas-Garcia, Isabel Illa
The chronic inflammatory neuropathies (CINs) are rare, very disabling autoimmune disorders that generally respond well to immune therapies such as intravenous immunoglobulin (IVIg). The most common forms of CIN are chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), multifocal motor neuropathy, and polyneuropathy associated with monoclonal gammopathy of unknown significance. The field of CIN has undergone a major advance with the identification of IgG4 autoantibodies directed against paranodal proteins in patients with CIDP...
July 14, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28708132/in-the-news-ean-highlights-european-success-in-neurology
#16
Ian Fyfe
No abstract text is available yet for this article.
July 14, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28685760/prion-disease-anti-prions-block-prion-disease-onset
#17
Charlotte Ridler
No abstract text is available yet for this article.
July 7, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28731040/er-stress-and-the-unfolded-protein-response-in-neurodegeneration
#18
REVIEW
Claudio Hetz, Smita Saxena
The clinical manifestation of neurodegenerative diseases is initiated by the selective alteration in the functionality of distinct neuronal populations. The pathology of many neurodegenerative diseases includes accumulation of misfolded proteins in the brain. In physiological conditions, the proteostasis network maintains normal protein folding, trafficking and degradation; alterations in this network - particularly disturbances to the function of endoplasmic reticulum (ER) - are thought to contribute to abnormal protein aggregation...
August 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28708134/neurodegenerative-disease-loss-of-tdp-43-in-microglia-friend-or-foe
#19
Charlotte Ridler
No abstract text is available yet for this article.
August 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28708131/a-clinicopathological-approach-to-the-diagnosis-of-dementia
#20
REVIEW
Fanny M Elahi, Bruce L Miller
The most definitive classification systems for dementia are based on the underlying pathology which, in turn, is categorized largely according to the observed accumulation of abnormal protein aggregates in neurons and glia. These aggregates perturb molecular processes, cellular functions and, ultimately, cell survival, with ensuing disruption of large-scale neural networks subserving cognitive, behavioural and sensorimotor functions. The functional domains affected and the evolution of deficits in these domains over time serve as footprints that the clinician can trace back with various levels of certainty to the underlying neuropathology...
August 2017: Nature Reviews. Neurology
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