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Nature Reviews. Neurology

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https://www.readbyqxmd.com/read/28303929/neuro-oncology-new-therapeutic-targets-for-diffuse-intrinsic-pontine-glioma
#1
Charlotte Ridler
No abstract text is available yet for this article.
March 17, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28303915/brain-imaging-applications-of-tau-pet-imaging
#2
Nobuyuki Okamura, Kazuhiko Yanai
No abstract text is available yet for this article.
March 17, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28303914/restoring-brain-function-after-stroke-bridging-the-gap-between-animals-and-humans
#3
REVIEW
Nick S Ward
Stroke is the leading cause of complex adult disability in the world. Recovery from stroke is often incomplete, which leaves many people dependent on others for their care. The improvement of long-term outcomes should, therefore, be a clinical and research priority. As a result of advances in our understanding of the biological mechanisms involved in recovery and repair after stroke, therapeutic opportunities to promote recovery through manipulation of poststroke plasticity have never been greater. This work has almost exclusively been carried out in preclinical animal models of stroke with little translation into human studies...
March 17, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28303913/multiple-system-atrophy-insights-into-a-rare-and-debilitating-movement-disorder
#4
REVIEW
Florian Krismer, Gregor K Wenning
Multiple system atrophy (MSA) is a devastating and fatal neurodegenerative disorder. The clinical presentation of this disease is highly variable, with parkinsonism, cerebellar ataxia and autonomic failure being the most common - and often debilitating - symptoms. These symptoms progress rapidly, and patients die from MSA-related complications after 9 years of symptom duration on average. Unfortunately, the course of the disease cannot be improved by drug or surgical treatment. In addition, symptomatic treatment options are currently limited, and therapeutic benefits are often only transient...
March 17, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28303912/new-technologies-for-the-assessment-of-neuropathies
#5
REVIEW
Roberto Gasparotti, Luca Padua, Chiara Briani, Giuseppe Lauria
Technical advances are rapidly changing the clinical and instrumental approach to peripheral nerve diseases. Magnetic resonance neurography, diffusion tensor imaging and nerve ultrasonography are increasingly entering the diagnostic workup of peripheral neuropathies as tools that complement neurophysiology and enable investigation of proximal structures, such as plexuses and roots. Progress in the design of magnetic resonance scanners and sequences, and the development of high-frequency ultrasound probes mean that high-resolution peripheral nerve imaging is possible, enabling detailed examination of nerve size, morphology and internal fascicular structure that can integrate nerve conduction studies into clinical practice...
March 17, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28303911/comorbidity-in-multiple-sclerosis-implications-for-patient-care
#6
REVIEW
Ruth Ann Marrie
Most efforts aimed at understanding the notable heterogeneity of outcomes in multiple sclerosis (MS) have focused on disease-specific factors, such as symptoms at initial presentation, initial relapse rate, and age at symptom onset. These factors, however, explain relatively little of the heterogeneity of disease outcomes. Owing to the high prevalence of comorbidity in MS and the potential for its prevention or treatment, comorbidity is of rising interest as a factor that could explain the heterogeneity of outcomes...
March 17, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28281535/epilepsy-common-and-rare-epilepsies-share-genetic-determinants
#7
Pasquale Striano, Federico Zara
No abstract text is available yet for this article.
March 10, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28281534/in-the-news-isc-2017-getting-the-heads-up-on-stroke
#8
Heather Wood
No abstract text is available yet for this article.
March 10, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28281533/alzheimer-disease-a-novel-human-mouse-chimaeric-model-of-alzheimer-disease
#9
Heather Wood
No abstract text is available yet for this article.
March 10, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28281532/multiple-sclerosis-stem-cell-treatment-suppresses-multiple-sclerosis-in-the-long-term
#10
Ian Fyfe
No abstract text is available yet for this article.
March 10, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28257129/traumatic-brain-injury-new-insights-into-the-long-term-effects-of-mild-brain-injury
#11
Charlotte Ridler
No abstract text is available yet for this article.
March 3, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28257128/cognitive-decline-in-parkinson-disease
#12
REVIEW
Dag Aarsland, Byron Creese, Marios Politis, K Ray Chaudhuri, Dominic H Ffytche, Daniel Weintraub, Clive Ballard
Dementia is a frequent problem encountered in advanced stages of Parkinson disease (PD). In recent years, research has focused on the pre-dementia stages of cognitive impairment in PD, including mild cognitive impairment (MCI). Several longitudinal studies have shown that MCI is a harbinger of dementia in PD, although the course is variable, and stabilization of cognition - or even reversal to normal cognition - is not uncommon. In addition to limbic and cortical spread of Lewy pathology, several other mechanisms are likely to contribute to cognitive decline in PD, and a variety of biomarker studies, some using novel structural and functional imaging techniques, have documented in vivo brain changes associated with cognitive impairment...
March 3, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28233842/epilepsy-could-autoantibodies-explain-epilepsy-with-unknown-aetiology
#13
Ian Fyfe
No abstract text is available yet for this article.
February 24, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28233841/stroke-stroke-thrombolysis-and-thrombectomy-not-stronger-together
#14
Elad I Levy, Maxim Mokin
No abstract text is available yet for this article.
February 24, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28233840/motor-neuron-disease-csf-suppresses-sonic-hedgehog-in-amyotrophic-lateral-sclerosis
#15
Heather Wood
No abstract text is available yet for this article.
February 24, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28211452/early-onset-and-delayed-onset-poststroke-dementia-revisiting-the-mechanisms
#16
REVIEW
Vincent C T Mok, Bonnie Y K Lam, Adrian Wong, Ho Ko, Hugh S Markus, Lawrence K S Wong
Incident stroke has long been recognized to cause dementia shortly after the event. Patients who survive stroke without early-onset poststroke dementia (PSD) are at a high risk of developing dementia months to years after the initial stroke incident, which has generated enthusiasm for exploring treatments to prevent delayed-onset PSD in survivors of stroke. However, results from clinical trials completed in the past 10-15 years have been disappointing. In light of these results, the present Review revisits the mechanisms of both early-onset and delayed-onset PSD and proposes preventive strategies and directions for future clinical trials...
February 17, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28211451/motor-neuron-disease-communication-for-completely-locked-in-patients
#17
Ian Fyfe
No abstract text is available yet for this article.
February 17, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28211450/corrigendum-brain-computer-interfaces-for-communication-and-rehabilitation
#18
Ujwal Chaudhary, Niels Birbaumer, Ander Ramos-Murguialday
No abstract text is available yet for this article.
February 17, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28186180/motor-neuron-disease-spinal-cord-morphometry-a-promising-technique-to-track-disease-course-in-als
#19
Heather Wood
No abstract text is available yet for this article.
February 10, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28186179/alzheimer-disease-twin-peaks-of-microglial-activation-observed-in-alzheimer-disease
#20
Heather Wood
No abstract text is available yet for this article.
February 10, 2017: Nature Reviews. Neurology
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