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Nature Reviews. Neurology

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https://www.readbyqxmd.com/read/28211452/early-onset-and-delayed-onset-poststroke-dementia-revisiting-the-mechanisms
#1
REVIEW
Vincent C T Mok, Bonnie Y K Lam, Adrian Wong, Ho Ko, Hugh S Markus, Lawrence K S Wong
Incident stroke has long been recognized to cause dementia shortly after the event. Patients who survive stroke without early-onset poststroke dementia (PSD) are at a high risk of developing dementia months to years after the initial stroke incident, which has generated enthusiasm for exploring treatments to prevent delayed-onset PSD in survivors of stroke. However, results from clinical trials completed in the past 10-15 years have been disappointing. In light of these results, the present Review revisits the mechanisms of both early-onset and delayed-onset PSD and proposes preventive strategies and directions for future clinical trials...
February 17, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28211451/motor-neuron-disease-communication-for-completely-locked-in-patients
#2
Ian Fyfe
No abstract text is available yet for this article.
February 17, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28211450/corrigendum-brain-computer-interfaces-for-communication-and-rehabilitation
#3
Ujwal Chaudhary, Niels Birbaumer, Ander Ramos-Murguialday
No abstract text is available yet for this article.
February 17, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28211449/translational-use-of-event-related-potentials-to-assess-circuit-integrity-in-asd
#4
REVIEW
Meera E Modi, Mustafa Sahin
Deficits in social cognition are the defining characteristic of autism spectrum disorder (ASD). Social cognition requires the integration of several neural circuits in a time-sensitive fashion, so impairments in social interactions could arise as a result of alterations in network connectivity. Electroencephalography (EEG) has revealed abnormalities in event related potentials (ERPs) evoked by auditory and visual sensory stimuli in humans with ASD, indicating disruption of neural connectivity. Similar abnormalities in sensory-evoked ERPs have been observed in animal models of ASD, suggesting that ERPs have the potential to provide a translational biomarker of the disorder...
February 17, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28186180/motor-neuron-disease-spinal-cord-morphometry-a-promising-technique-to-track-disease-course-in-als
#5
Heather Wood
No abstract text is available yet for this article.
February 10, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28186179/alzheimer-disease-twin-peaks-of-microglial-activation-observed-in-alzheimer-disease
#6
Heather Wood
No abstract text is available yet for this article.
February 10, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28186178/stroke-sleep-related-breathing-disorders-after-stroke-are-not-linked-to-lesion-location
#7
Heather Wood
No abstract text is available yet for this article.
February 10, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28186177/the-far-reaching-scope-of-neuroinflammation-after-traumatic-brain-injury
#8
REVIEW
Dennis W Simon, Mandy J McGeachy, Hülya Bayır, Robert S B Clark, David J Loane, Patrick M Kochanek
The 'silent epidemic' of traumatic brain injury (TBI) has been placed in the spotlight as a result of clinical investigations and popular press coverage of athletes and veterans with single or repetitive head injuries. Neuroinflammation can cause acute secondary injury after TBI, and has been linked to chronic neurodegenerative diseases; however, anti-inflammatory agents have failed to improve TBI outcomes in clinical trials. In this Review, we therefore propose a new framework of targeted immunomodulation after TBI for future exploration...
February 10, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28155893/neuroimmunology-microglia-induced-reactive-astrocytes-toxic-players-in-neurological-disease
#9
Charlotte Ridler
No abstract text is available yet for this article.
February 3, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28155892/alzheimer-disease-csf-biomarkers-for-alzheimer-disease-approaching-consensus
#10
Douglas R Galasko, Leslie M Shaw
No abstract text is available yet for this article.
February 3, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28155891/stroke-ct-imaging-markers-predict-outcome-of-ischaemic-stroke
#11
Ian Fyfe
No abstract text is available yet for this article.
February 3, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28134255/motor-neuron-disease-targeting-multiple-mechanisms-to-treat-amyotrophic-lateral-sclerosis
#12
Heather Wood
No abstract text is available yet for this article.
January 30, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28134254/schwann-cell-interactions-with-axons-and-microvessels-in-diabetic-neuropathy
#13
REVIEW
Nádia P Gonçalves, Christian B Vægter, Henning Andersen, Leif Østergaard, Nigel A Calcutt, Troels S Jensen
The prevalence of diabetes worldwide is at pandemic levels, with the number of patients increasing by 5% annually. The most common complication of diabetes is peripheral neuropathy, which has a prevalence as high as 50% and is characterized by damage to neurons, Schwann cells and blood vessels within the nerve. The pathogenic mechanisms of diabetic neuropathy remain poorly understood, impeding the development of targeted therapies to treat nerve degeneration and its most disruptive consequences of sensory loss and neuropathic pain...
January 30, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28106068/alzheimer-disease-misfolded-diabetes-mellitus-peptide-seeds-amyloid-%C3%AE-aggregation
#14
Charlotte Ridler
No abstract text is available yet for this article.
January 20, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28106063/dementia-could-heavy-traffic-drive-dementia-risk
#15
Louise Adams
No abstract text is available yet for this article.
January 20, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28145448/stroke-thrombolytic-removal-of-intraventricular-haemorrhage-does-not-improve-outcomes
#16
Heather Wood
No abstract text is available yet for this article.
February 1, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28145447/unruptured-intracranial-aneurysms-development-rupture-and-preventive-management
#17
Nima Etminan, Gabriel J Rinkel
No abstract text is available yet for this article.
February 1, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28145446/migraine-migraine-is-associated-with-increased-risk-of-perioperative-ischaemic-stroke
#18
Heather Wood
No abstract text is available yet for this article.
February 1, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28145445/peripheral-neuropathies-atypical-charcot-marie-tooth-disease-linked-to-sphingosine-1-phosphate-lyase-deficiency
#19
Heather Wood
No abstract text is available yet for this article.
February 1, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28145444/motor-neuron-disease-sparing-of-oligodendrocytes-in-a-mouse-model-of-spinal-muscular-atrophy
#20
Heather Wood
No abstract text is available yet for this article.
February 1, 2017: Nature Reviews. Neurology
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