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Nature Reviews. Neurology

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https://www.readbyqxmd.com/read/28708134/neurodegenerative-disease-loss-of-tdp-43-in-microglia-friend-or-foe
#1
Charlotte Ridler
No abstract text is available yet for this article.
July 14, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28708133/autoantibodies-in-chronic-inflammatory-neuropathies-diagnostic-and-therapeutic-implications
#2
REVIEW
Luis Querol, Jérôme Devaux, Ricard Rojas-Garcia, Isabel Illa
The chronic inflammatory neuropathies (CINs) are rare, very disabling autoimmune disorders that generally respond well to immune therapies such as intravenous immunoglobulin (IVIg). The most common forms of CIN are chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), multifocal motor neuropathy, and polyneuropathy associated with monoclonal gammopathy of unknown significance. The field of CIN has undergone a major advance with the identification of IgG4 autoantibodies directed against paranodal proteins in patients with CIDP...
July 14, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28708132/in-the-news-ean-highlights-european-success-in-neurology
#3
Ian Fyfe
No abstract text is available yet for this article.
July 14, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28708131/a-clinicopathological-approach-to-the-diagnosis-of-dementia
#4
REVIEW
Fanny M Elahi, Bruce L Miller
The most definitive classification systems for dementia are based on the underlying pathology which, in turn, is categorized largely according to the observed accumulation of abnormal protein aggregates in neurons and glia. These aggregates perturb molecular processes, cellular functions and, ultimately, cell survival, with ensuing disruption of large-scale neural networks subserving cognitive, behavioural and sensorimotor functions. The functional domains affected and the evolution of deficits in these domains over time serve as footprints that the clinician can trace back with various levels of certainty to the underlying neuropathology...
July 14, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28685760/prion-disease-anti-prions-block-prion-disease-onset
#5
Charlotte Ridler
No abstract text is available yet for this article.
July 7, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28685759/parkinson-disease-defining-pd-subtypes-a-step-toward-personalized-management
#6
Caroline H Williams-Gray, Roger A Barker
No abstract text is available yet for this article.
July 7, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28664909/chemotherapy-induced-peripheral-neurotoxicity-management-informed-by-pharmacogenetics
#7
REVIEW
Andreas A Argyriou, Jordi Bruna, Armando A Genazzani, Guido Cavaletti
The increasing availability of sophisticated methods to characterize human genetic variation has enabled pharmacogenetic data to be used not only to predict responses to treatment (in the context of so-called personalized medicine), but also to identify patients at high or low risk of specific treatment-related adverse effects. Over the past two decades, extensive attempts have been made to understand the genetic basis of chemotherapy-induced peripheral neurotoxicity (CIPN), one of the most severe non-haematological adverse effects of cancer treatment...
June 30, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28664908/parkinson-disease-t-cells-recognize-%C3%AE-synuclein-peptides-in-parkinson-disease
#8
Ian Fyfe
No abstract text is available yet for this article.
June 30, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28643808/parkinson-disease-deep-brain-stimulation-making-the-right-connections
#9
Charlotte Ridler
No abstract text is available yet for this article.
June 23, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28643807/infectious-disease-musashi-1-protein-could-mediate-the-effects-of-zika-virus-on-brain-development
#10
Heather Wood
No abstract text is available yet for this article.
June 23, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28643806/dementia-persistent-pain-might-be-a-harbinger-of-cognitive-decline-in-older-people
#11
Heather Wood
No abstract text is available yet for this article.
June 23, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28643805/parkinson-disease-plasma-%C3%AE-synuclein-a-potential-marker-of-cognitive-impairment-in-parkinson-disease
#12
Heather Wood
No abstract text is available yet for this article.
June 23, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28621771/repeat-expansion-disorders-new-evidence-for-rna-gelation-in-repeat-expansion-disorders
#13
Heather Wood
No abstract text is available yet for this article.
June 16, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28621767/neuroimmunology-complement-is-no-bystander-in-cns-degeneration
#14
Ian Fyfe
No abstract text is available yet for this article.
June 16, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28621764/neuroimmunology-b-cells-and-variant-baff-in-autoimmune-disease
#15
Manuel Comabella
No abstract text is available yet for this article.
June 16, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28621769/alzheimer-disease-sniffing-out-a-marker-of-early-alzheimer-disease
#16
Ian Fyfe
No abstract text is available yet for this article.
June 9, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28548107/current-controversies-in-brain-death-determination
#17
REVIEW
Ariane Lewis, David Greer
Although the concept of brain death is accepted by the majority of physicians, lawyers, ethicists and society at large, controversies about determination of death by neurological criteria persist, and often reach the public eye. In this article, we examine four prominent controversial brain death cases from 2013-2016. We review current controversies, including protocol variability, recognition of the American Academy of Neurology (AAN) criteria for brain death as an accepted medical standard, and management of objections to discontinuation of organ support after determination of brain death...
May 26, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28524172/in-the-news-clinical-trials-excite-at-aan-2017
#18
Charlotte Ridler
No abstract text is available yet for this article.
May 19, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28621770/epilepsy-a-new-guideline-on-sudden-unexpected-death-in-epilepsy
#19
Daniel Friedman
No abstract text is available yet for this article.
July 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28621768/imaging-and-fluid-biomarkers-in-frontotemporal-dementia
#20
REVIEW
Lieke H Meeter, Laura Donker Kaat, Jonathan D Rohrer, John C van Swieten
Frontotemporal dementia (FTD), the second most common type of presenile dementia, is a heterogeneous neurodegenerative disease characterized by progressive behavioural and/or language problems, and includes a range of clinical, genetic and pathological subtypes. The diagnostic process is hampered by this heterogeneity, and correct diagnosis is becoming increasingly important to enable future clinical trials of disease-modifying treatments. Reliable biomarkers will enable us to better discriminate between FTD and other forms of dementia and to predict disease progression in the clinical setting...
July 2017: Nature Reviews. Neurology
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