journal
MENU ▼
Read by QxMD icon Read
search

Cancer Cytopathology

journal
https://www.readbyqxmd.com/read/30239146/petals-and-thorns-in-programmed-death-ligand-1-testing-is-all-non-small-cell-lung-cancer-diagnostic-material-suitable
#1
LETTER
Sara Bravaccini, Giuseppe Bronte
No abstract text is available yet for this article.
September 21, 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30239144/reply-to-petals-and-thorns-in-programmed-death-ligand-1-testing-is-all-non-small-cell-lung-cancer-diagnostic-material-suitable
#2
LETTER
Eleanor Russell-Goldman, Lynette M Sholl, Marina Vivero
No abstract text is available yet for this article.
September 21, 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30230262/use-of-a-low-cost-telecytopathology-method-for-remote-assessment-of-thyroid-fnas
#3
Camilla Costa, Ricardo Garcia Pastorello, André Mendonça, Caroline Tamaro, Caroline Morais, Barbara Barbosa, Karina Braga Ribeiro, Alessandra Caivano, Mauro Ajaj Saieg
BACKGROUND: Rapid on-site evaluation is a great tool for optimizing the adequacy and quality of cytologic samples. The objective of the current study was to analyze a low-cost telecytopathology method for the remote assessment of thyroid fine-needle aspiration biopsies (FNABs), with comparison of the primarily rendered adequacy and diagnosis with the final conventional analysis. METHODS: Material collected from thyroid FNABs was immediately smeared onto glass slides and stained with Diff-Quik...
September 19, 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30203925/improved-diagnostic-precision-of-urine-cytology-by-implementation-of-the-paris-system-and-the-use-of-cell-blocks
#4
Emily Chan, Ronald Balassanian, Z Laura Tabatabai, Hubing Lou, Poonam Vohra
BACKGROUND: The Paris System for Reporting Urinary Cytology (TPS) published in 2016 provides a standardized approach to evaluating urine cytology. In the authors' practice, a TPS-like approach was adopted in 2012 using similarly defined cytologic criteria and correlating cystoscopic findings, and they also began incorporating the use of cell block (CB) material. The objective of the current study was to assess whether this TPS-like approach with the use of CB, as well as direct implementation of TPS, improved the diagnostic value of urine cytology...
September 11, 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30199148/molecular-genetic-alterations-in-thyroid-transcription-factor-1-negative-lung-adenocarcinoma-in-cytology-specimens-a-subset-with-aggressive-behavior-and-a-poor-prognosis
#5
Erika F Rodriguez, Christopher J VandenBussche, Sayanan Chowsilpa, Zahra Maleki
BACKGROUND: Patients with thyroid transcription factor 1 (TTF1)-negative pulmonary adenocarcinoma (ADC) have been reported to have a worse prognosis and to lack epidermal growth factor receptor (EGFR) mutations. This study describes a series of cytology specimens from patients with clinically confirmed pulmonary carcinoma negative for TTF1. METHODS: A search for TTF1-negative ADC from 2010 to 2017 was performed. Each patient's clinical history, pathology specimens, and molecular results were noted...
September 10, 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30194715/flow-immunophenotyping-of-benign-lymph-nodes-sampled-by-fna-representative-with-diagnostic-pitfalls
#6
Gregory D Scott, Hubert D Lau, Jason H Kurzer, Christina S Kong, Dita A Gratzinger
BACKGROUND: Fine-needle aspiration with flow cytometry (FNA-FC) is routinely used in the evaluation of lymph nodes suspicious for lymphoma, yet data comparing immunophenotype distributions and outliers in benign lymph nodes sampled by fine-needle aspiration (FNA) versus excision are lacking. METHODS: Flow cytometry data from 289 benign lymph node FNA cases were assessed for the overall antigen distribution, with a focus on outliers relevant to the diagnosis of lymphoma...
September 7, 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30193011/evaluation-of-diagnostic-accuracy-and-a-practical-algorithmic-approach-for-the-diagnosis-of-renal-masses-by-fna
#7
Hubert D Lau, Christina S Kong, Chia-Sui Kao
BACKGROUND: The classification of renal neoplasms is essential for oncologic risk stratification and clinical management, and an accurate pretreatment pathologic diagnosis can provide useful guidance for active surveillance, minimally invasive ablative therapy, or surgical resection and can reduce the incidence of overtreatment. Previous studies evaluating the diagnostic accuracy of fine-needle aspiration (FNA) and core-needle biopsy (CNB) for renal masses are limited and show variable results...
September 7, 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30156778/ancillary-studies-in-cytology-secondary-or-necessary
#8
REVIEW
Douglas P Clark
Ancillary studies are rapidly becoming an integral and necessary aspect of cytologic analysis. In addition to morphologic features, cytologic specimens contain an enormous amount of information content within their molecules that should be tapped to add value to these samples. Fortunately, a large number of existing and emerging technologies exist to provide access to this information. Adoption of these technologies will require continued attention to fundamental aspects of specimen procurement, handling, and processing to ensure testing accuracy...
August 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30156777/ancillary-tests-in-the-diagnosis-of-liver-and-pancreatic-neoplasms
#9
REVIEW
Joseph Misdraji, Barbara A Centeno, Martha B Pitman
Ancillary tests in the diagnosis of liver and pancreatic neoplasms include a wide array of immunostains and molecular diagnostic tests, and the selection of tests is based on the differential diagnosis. This review discusses ancillary tests in the diagnosis of liver tumors, including benign and malignant primary tumors as well as metastatic tumors to the liver. In addition, ancillary tests for the diagnosis of both solid and cystic pancreatic neoplasms, including molecular tests in these lesions are also reviewed...
August 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30156776/identification-of-infectious-organisms-in-cytopathology-a-review-of-ancillary-diagnostic-techniques
#10
REVIEW
Derek B Allison, Patricia J Simner, Syed Z Ali
Cytology samples obtained from exfoliative sources and fine-needle aspiration (FNA) procedures can all be used to detect microorganisms and/or the associated cytopathologic effects (CPE) caused by an infection. There are many advantages to utilizing cytology samples as an adjunct to routine microbiology laboratory methods. For example, cytology samples can be obtained by non-invasive and minimally invasive techniques, and interpretation is affordable, accurate, and fast. Furthermore, routine cytology stains, including the Papanicolaou (Pap) and the Diff-Quik (DQ) stains, can adequately identify a number of microorganisms...
August 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30156775/ancillary-molecular-testing-of-indeterminate-thyroid-nodules
#11
REVIEW
Esther Diana Rossi, Luigi Maria Larocca, Liron Pantanowitz
Cytological specimens from thyroid nodules are increasingly being adopted as the first available material for cost effectively managing patients in the era of personalized medicine. Cytology aspirates not only play a central role in providing accurate diagnoses, but are also being collected for ancillary molecular testing. Molecular analysis, including the evaluation of somatic mutations and other genomic alterations, has accordingly become well integrated in the cytological workup of thyroid lesions. Appropriately handled thyroid cytology preparations provide well-preserved and adequately cellular material with improved DNA/RNA quantity...
August 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30156774/application-of-ancillary-studies-in-soft-tissue-cytology-using-a-pattern-based-approach
#12
REVIEW
Ivan Chebib, Vickie Y Jo
The cytologic diagnosis of soft tissue neoplasms has undergone many advances due to the development of numerous useful immunohistochemical markers and molecular assays that target specific molecular alterations. Ancillary tests, when used in conjunction with clinical, radiologic, and cytomorphologic features, allow for more accurate classification and refinement of differential diagnoses of soft tissue neoplasms. Soft tissue tumors encompass a diverse group of tumors showing a wide range of cytomorphologies that can be broadly grouped as lipomatous, myxoid, spindled, pleomorphic, round cell, and epithelioid...
August 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30156773/navigating-the-diverse-array-of-ancillary-markers-available-for-cytology
#13
EDITORIAL
William C Faquin
No abstract text is available yet for this article.
August 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30156772/a-practical-guide-for-ancillary-studies-in-pulmonary-cytologic-specimens
#14
REVIEW
Manon Auger, Fadi Brimo, Yonca Kanber, Pierre O Fiset, Sophie Camilleri-Broet
Although most pulmonary cytologic specimens obtained by either exfoliation or fine needle aspirates can be reliably and accurately diagnosed based on pure morphologic criteria alone, a small proportion of cases require ancillary studies for either refining a diagnosis, for resolving a differential diagnosis or increasingly, for predictive purposes in primary lung carcinomas. This article aims to provide practical guidance on the use of common ancillary studies in pulmonary cytologic specimens. Cancer Cytopathol 2018;000:000-000...
August 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30156771/lymph-node-cytopathology-essential-ancillary-studies-as-applied-to-lymphoproliferative-neoplasms
#15
REVIEW
Ming Jin, Paul E Wakely
Ancillary testing is absolutely integral to the correct recognition and classification of lymphoid neoplasms as procured with the fine-needle aspiration (FNA) biopsy technique. In patients with a newly diagnosed lymphoid neoplasm, immunophenotyping with flow cytometry, immunohistochemistry, or both is a standard that is currently expected by oncologists before any form of therapy is initiated. This is often the case also for patients with recurrent/relapsed disease. The cellular material obtained with FNA is perfectly suited to meet this demand...
August 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30156770/ancillary-studies-in-fine-needle-aspiration-of-the-kidney
#16
REVIEW
Andrew A Renshaw, Edwin W Gould
An increasing number of renal cell carcinomas (RCCs) require ancillary studies for diagnosis. The majority of renal fine needle aspirates do not require ancillary studies. Among the most common useful stains are cytokeratin 7 (separating clear cell RCC [negative] from papillary RCC, clear cell papillary RCC, and multilocular cystic RCC [positive] as well as separating chromophobe RCC [diffusely positive] from oncocytoma [focally positive/negative]) and CD117 (separating chromophobe RCC and oncocytoma [positive] from granular variants of clear cell RCC [negative])...
August 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30156769/cancer-of-unknown-primary-ancillary-testing-of-cytologic-and-small-biopsy-specimens-in-the-era-of-targeted-therapy
#17
REVIEW
Morgan L Cowan, Christopher J VandenBussche
Initial evaluation of patients presenting with a suspected malignancy without a clear clinical or radiologic impression of a primary site (so-called cancer of unknown primary, or CUP) frequently includes fine needle aspiration (FNA) to both establish a diagnosis and procure tissue for additional studies. Careful management of limited specimen material is especially important in the modern era, when molecular studies may take precedence over a more definitive tissue diagnosis. This review summarizes our practice habits when encountering a CUP...
August 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30156768/ancillary-studies-in-pleural-pericardial-and-peritoneal-effusion-cytology
#18
REVIEW
Kaitlin E Sundling, Edmund S Cibas
Pleural, pericardial, and peritoneal effusion specimens present diagnostic challenges and clinical opportunities for cytology. For the patient, these specimens may be the first diagnosis of malignancy or the first sign of disease recurrence. This review aims to provide useful approaches with which to resolve key difficulties in cytologic diagnosis through the use of ancillary studies, focusing on immunohistochemistry. These approaches are suggested in concert with clinical, radiographic, and morphologic findings...
August 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30156767/ancillary-testing-in-salivary-gland-cytology-a-practical-guide
#19
REVIEW
Vickie Y Jo, Jeffrey F Krane
Salivary gland cytology is challenging, and historically the role of ancillary testing has been limited. However, numerous molecular/genetic advances in the understanding of salivary gland neoplasms during the last decade have facilitated the development of many useful diagnostic markers, such as PLAG1 and HMGA2 immunohistochemistry for pleomorphic adenoma and ETV6 fluorescence in situ hybridization for secretory carcinoma. Numerous salivary gland neoplasms are characterized by specific molecular/genetic alterations, many of which can be identified on cytologic preparations by karyotype analysis, fluorescence in situ hybridization, or immunohistochemical surrogates...
August 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/30156766/pre-analytic-error-a-significant-patient-safety-risk
#20
REVIEW
Yael K Heher, Yigu Chen, Paul A VanderLaan
Ancillary testing in cytopathology has grown dramatically over the past decade, enhancing the clinical value of cytology specimens obtained via minimally invasive methods. However, a complex testing landscape brings with it new and emerging risks to patient safety. Recognition of complicated systems issues as well as shared responsibility in process ownership can help to minimize safety risks. Because pre-analytic factors account for the majority of errors in pathology, attention to operational steps (test ordering, specimen collection, specimen transport, specimen accessioning, and specimen processing) is critical for successful quality improvement programs...
August 2018: Cancer Cytopathology
journal
journal
42289
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"