journal
MENU ▼
Read by QxMD icon Read
search

Chinese Journal of Cancer

journal
https://www.readbyqxmd.com/read/29020982/the-prognostic-value-of-c-x-c-motif-chemokine-receptor-4-in-patients-with-sporadic-malignant-peripheral-nerve-sheath-tumors
#1
Chao Zhang, Fang-Yuan Chang, Wen-Ya Zhou, Ji-Long Yang
BACKGROUND: Recent studies indicate that C-X-C motif chemokine receptor 4 (CXCR4) and its ligand, C-X-C motif chemokine ligand 12 (CXCL12), stimulate expression of the cell cycle regulatory protein Cyclin D1 in neurofibromatosis 1-associated malignant peripheral nerve sheath tumor (MPNST) cells and promote their proliferation. In this study, we measured the expression of CXCR4, CXCL12, and Cyclin D1 proteins in sporadic MPNST tissues from Chinese patients and investigated their prognostic values...
October 11, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28974261/the-150-most-important-questions-in-cancer-research-and-clinical-oncology-series-questions-57-66-edited-by-chinese-journal-of-cancer
#2
EDITORIAL
(no author information available yet)
Since the beginning of 2017, Chinese Journal of Cancer has published a series of important questions in cancer research and clinical oncology, which sparkle diverse thoughts, interesting communications, and potential collaborations among researchers all over the world. In this article, 10 more questions are presented as followed. Question 57. What are the major stresses that drive the formation, progression, and metastasis of a cancer? Question 58. What is the mechanism responsible for altering an acidic intracellular pH and a basic extracellular pH in normal tissue cells to a basic intracellular pH and an acidic extracellular pH in cancer cells, a fundamental and yet largely ignored phenomenon? Question 59...
October 3, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28969708/pathologic-response-after-preoperative-therapy-predicts-prognosis-of-chinese-colorectal-cancer-patients-with-liver-metastases
#3
Yun Wang, Yun-Fei Yuan, Hao-Cheng Lin, Bin-Kui Li, Feng-Hua Wang, Zhi-Qiang Wang, Pei-Rong Ding, Gong Chen, Xiao-Jun Wu, Zhen-Hai Lu, Zhi-Zhong Pan, De-Sen Wan, Peng Sun, Shu-Mei Yan, Rui-Hua Xu, Yu-Hong Li
BACKGROUND: Pathologic response is evaluated according to the extent of tumor regression and is used to estimate the efficacy of preoperative treatment. Several studies have reported the association between the pathologic response and clinical outcomes of colorectal cancer patients with liver metastases who underwent hepatectomy. However, to date, no data from Chinese patients have been reported. In this study, we aimed to evaluate the association between the pathologic response to pre-hepatectomy chemotherapy and prognosis in a cohort of Chinese patients...
October 2, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28950898/tripartite-motif-containing-3-trim3-inhibits-tumor-growth-and-metastasis-of-liver-cancer
#4
Xu-Qiong Huang, Xiao-Fei Zhang, Jin-Hua Xia, Jie Chao, Qiu-Zhong Pan, Jing-Jing Zhao, Zi-Qi Zhou, Chang-Long Chen, Yan Tang, De-Sheng Weng, Jian-Hua Zhang, Jian-Chuan Xia
BACKGROUND: Reduced expression of tripartite motif-containing 3 (TRIM3) has been reported to be involved in the pathogenesis of human glioblastoma. In our previous research, we found that TRIM3 expression was markedly reduced in human primary hepatocellular carcinoma (HCC) tissues and that low TRIM3 expression was associated with short survival of HCC patients. However, the role of TRIM3 in liver cancer remains unknown. This study aimed to investigate the function of TRIM3 in liver cancer cells...
September 26, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28931426/effects-of-dosimetric-inadequacy-on-local-control-and-toxicities-in-the-patients-with-t4-nasopharyngeal-carcinoma-extending-into-the-intracranial-space-and-treated-with-intensity-modulated-radiotherapy-plus-chemotherapy
#5
Fen Xue, Chao-Su Hu, Xia-Yun He
BACKGROUND: To protect neurological tissues, underdosing occurs in most cases of T4 nasopharyngeal carcinoma (NPC) with intracranial extension. In this study, we aimed to evaluate the effect of dosimetric inadequacy on local control and late neurological toxicities for patients treated with intensity-modulated radiotherapy (IMRT) plus chemotherapy. METHODS: We prospectively enrolled patients who had non-metastatic T4 NPC with intracranial extension treated between January 2009 and November 2013...
September 20, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28899420/prognostic-value-of-systemic-immune-inflammation-index-in-patients-with-gastric-cancer
#6
Kang Wang, Feiyu Diao, Zhijun Ye, Xinhua Zhang, Ertao Zhai, Hui Ren, Tong Li, Hui Wu, Yulong He, Shirong Cai, Jianhui Chen
BACKGROUND: Inflammation-based indexes have been used to predict survival and recurrence in cancer patients. Systemic immune-inflammation index (SII) was reported to be associated with prognosis in some malignant tumors. In the present study, we aimed to explore the association between SII and the prognosis of patients with gastric cancer. METHODS: We retrospectively analyzed data from 444 gastric cancer patients who underwent gastrectomy at the First Affiliated Hospital of Sun Yat-sen University between January 1994 and December 2005...
September 12, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28893309/efficacy-and-safety-of-controlled-release-oxycodone-naloxone-versus-controlled-release-oxycodone-in-korean-patients-with-cancer-related-pain-a-randomized-controlled-trial
#7
Kyung-Hee Lee, Tae Won Kim, Jung-Hun Kang, Jin-Soo Kim, Jin-Seok Ahn, Sun-Young Kim, Hwan-Jung Yun, Young-Jun Eum, Sung Ae Koh, Min Kyoung Kim, Yong Sang Hong, Jeong Eun Kim, Gyeong-Won Lee
BACKGROUND: Controlled-release oxycodone/naloxone (OXN-CR) maintains the effect of opioid-induced analgesia through oxycodone while reducing the occurrence rate of opioid-induced constipation through naloxone. The present study was designed to assess the non-inferiority of OXN-CR to controlled-release oxycodone (OX-CR) for the control of cancer-related pain in Korean patients. METHODS: In this randomized, open-labeled, parallel-group, phase IV study, we enrolled patients aged 20 years or older with moderate to severe cancer-related pain [numeric rating scale (NRS) pain score ≥4] from seven Korean oncology/hematology centers...
September 11, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28882179/medical-expenditure-for-esophageal-cancer-in-china-a-10-year-multicenter-retrospective-survey-2002-2011
#8
Lan-Wei Guo, Hui-Yao Huang, Ju-Fang Shi, Li-Hong Lv, Ya-Na Bai, A-Yan Mao, Xian-Zhen Liao, Guo-Xiang Liu, Jian-Song Ren, Xiao-Jie Sun, Xin-Yu Zhu, Jin-Yi Zhou, Ji-Yong Gong, Qi Zhou, Lin Zhu, Yu-Qin Liu, Bing-Bing Song, Ling-Bin Du, Xiao-Jing Xing, Pei-An Lou, Xiao-Hua Sun, Xiao Qi, Shou-Ling Wu, Rong Cao, Li Lan, Ying Ren, Kai Zhang, Jie He, Jian-Gong Zhang, Min Dai
BACKGROUND: Esophageal cancer is associated with substantial disease burden in China, and data on the economic burden are fundamental for setting priorities in cancer interventions. The medical expenditure for the diagnosis and treatment of esophageal cancer in China has not been fully quantified. This study aimed to examine the medical expenditure of Chinese patients with esophageal cancer and the associated trends. METHODS: From 2012 to 2014, a hospital-based multicenter retrospective survey was conducted in 37 hospitals in 13 provinces/municipalities across China as a part of the Cancer Screening Program of Urban China...
September 7, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28877745/erythrocytosis-caused-by-giant-chromophobe-renal-cell-carcinoma-a-case-report-indicating-a-9-year-misdiagnosis-of-polycythemia-vera
#9
Renbo Guo, Yiran Liang, Lei Yan, Zhonghua Xu, Juchao Ren
BACKGROUND: Erythrocytosis, a rare paraneoplastic syndrome, generally occurs in patients with clear cell renal cell carcinoma and has never been reported in patients with chromophobe renal cell carcinoma. CASE PRESENTATION: We report a case of a young man suffering from a giant (22-cm) mass on his left kidney. Because of a history of polycythemia vera, the patient had been treated for the condition for 9 years. Radical nephrectomy was successfully performed, and the postoperative pathologic examination confirmed a diagnosis of chromophobe renal cell carcinoma...
September 6, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28870229/potential-factors-associated-with-clinical-stage-of-nasopharyngeal-carcinoma-at-diagnosis-a-case-control-study
#10
Jun-Ting Ren, Meng-Yu Li, Xiao-Wen Wang, Wen-Qiong Xue, Ze-Fang Ren, Wei-Hua Jia
BACKGROUND: In China, most patients with nasopharyngeal carcinoma (NPC) are diagnosed at a late stage and consequently have a poor prognosis. This study aimed to investigate potential factors associated with the clinical stage of NPC at diagnosis. METHODS: Data were obtained from 118 patients with early-stage NPC and 274 with late-stage NPC who were treated at Sun Yat-sen University Cancer Center between August 2014 and July 2015. Patients were individually matched by age, sex, and residence, and a conditional logistic regression model was applied to assess the associations of clinical stage at diagnosis with socioeconomic status indicators, knowledge of NPC, physical examinations, patient interval, and risk factors for NPC...
September 4, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28854960/erratum-to-cancer-chemoprevention-through-dietary-flavonoids-what-s-limiting
#11
Haneen Amawi, Charles R Ashby, Amit K Tiwari
No abstract text is available yet for this article.
August 30, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28847311/the-150-most-important-questions-in-cancer-research-and-clinical-oncology-series-questions-50-56
#12
EDITORIAL
(no author information available yet)
Since the beginning of 2017, Chinese Journal of Cancer has published a series of important questions in cancer research and clinical oncology, which sparkle diverse thoughts, interesting communications, and potential collaborations among researchers all over the world. In this article, seven more questions are presented as followed. Question 50. When tumor cells spread from primary site to distant sites, are they required to be "trained" or "armed" in the bone marrow niche prior to colonizing soft tissues? Question 51...
August 29, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28826400/at-home-cancer-screening-a-solution-for-china-and-other-developing-countries-with-a-large-population-and-limited-number-of-healthcare-practitioners
#13
EDITORIAL
Chao-Nan Qian
Five-year survival rate for patients with all cancers combined, in China, is only 30.9%, which is much lower than those in developed countries. The three main reasons for the low cancer curative rates in China include differences in the spectrum of cancer types, in early detection rates, and in the percentage of cancer patients receiving standardized treatment between China and developed countries. The most important mechanism for improving the curative rate is to improve early detection rates of major cancers in China using novel and affordable technologies that can be operated at home by the patients themselves...
August 21, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28823251/awakening-immunity-against-cancer-a-2017-primer-for-clinicians
#14
EDITORIAL
Amit Jain, Qing Zhang, Han-Chong Toh
Cancer immunotherapy has finally joined the pillars of cancer treatment-surgery, radiation, chemotherapy, hormonal therapy, and targeted therapy-in improving cancer patient lives. In the last 5 years, the development of immune checkpoint inhibitor and T cell therapy, particularly chimeric antigen receptor (CAR) T-cell therapy, has been remarkable for the speed, scale, and number of drug approvals. Still, these treatments may also bring unusual adverse effects and clinical outcomes including unprecedented long-term survival...
August 20, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28818111/estimates-of-cancer-incidence-and-mortality-in-china-2013
#15
Rongshou Zheng, Hongmei Zeng, Siwei Zhang, Wanqing Chen
INTRODUCTION: Population-based cancer registration data are collected by the National Central Cancer Registry in China every year. Cancer incident cases and cancer deaths in 2013 were analyzed. METHODS: Through the procedure of quality control, reported data from 255 registries were accepted to establish the national database for cancer estimates. Incidences and mortalities were calculated with stratification by area (urban/rural), sex (male/female), age group (0, 1-4, 5-9, 10-14 … 80-84, and 85-year-old and above), and cancer site...
August 17, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28818096/immunohistochemical-prognostic-markers-of-esophageal-squamous-cell-carcinoma-a-systematic-review
#16
Chunni Wang, Jingnan Wang, Zhaoli Chen, Yibo Gao, Jie He
BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy, with a high incidence and poor prognosis. In the past several decades, hundreds of proteins have been reported to be associated with the prognosis of ESCC, but none has been widely accepted to guide clinical care. This study aimed to identify proteins with great potential for predicting prognosis of ESCC. METHODS: We conducted a systematic review on immunohistochemical (IHC) prognostic markers of ESCC according to the 2009 Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Guidelines...
August 17, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28789709/comparison-of-efficacy-safety-and-quality-of-life-between-sorafenib-and-sunitinib-as-first-line-therapy-for-chinese-patients-with-metastatic-renal-cell-carcinoma
#17
Wen Cai, Wen Kong, Baijun Dong, Jin Zhang, Yonghui Chen, Wei Xue, Yiran Huang, Lixin Zhou, Jiwei Huang
BACKGROUND: Sorafenib and sunitinib are widely used as first-line targeted therapy for metastatic renal cell carcinoma (mRCC) in China. This study aimed to compare the efficacy, safety, and quality of life (QoL) in Chinese mRCC patients treated with sorafenib and sunitinib as first-line therapy. METHODS: Clinical data of patients with mRCC who received sorafenib (400 mg twice daily; 4 weeks) or sunitinib (50 mg twice daily; on a schedule of 4 weeks on treatment followed by 2 weeks off) were retrieved...
August 8, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28756771/prognostic-role-of-abo-blood-type-in-patients-with-extranodal-natural-killer-t-cell-lymphoma-nasal-type-a-triple-center-study
#18
Ya-Jun Li, Ping-Yong Yi, Ji-Wei Li, Xian-Ling Liu, Tian Tang, Pei-Ying Zhang, Wen-Qi Jiang
BACKGROUND: The prognostic significance of ABO blood type for lymphoma is largely unknown. We evaluated the prognostic role of ABO blood type in patients with extranodal natural killer (NK)/T-cell lymphoma (ENKTL). METHODS: We retrospectively analyzed clinical data of 697 patients with newly diagnosed ENKTL from three cancer centers. The prognostic value of ABO blood type was evaluated using Kaplan-Meier curves and Cox proportional hazard models. The prognostic values of the International Prognostic Index (IPI) and the Korean Prognostic Index (KPI) were also evaluated...
July 31, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28756770/synthetic-lethal-short-hairpin-rna-screening-reveals-that-ring-finger-protein-183-confers-resistance-to-trametinib-in-colorectal-cancer-cells
#19
Rong Geng, Xin Tan, Zhixiang Zuo, Jiangxue Wu, Zhizhong Pan, Wei Shi, Ranyi Liu, Chen Yao, Gaoyuan Wang, Jiaxin Lin, Lin Qiu, Wenlin Huang, Shuai Chen
BACKGROUND: The mitogen-activated extracellular signal-regulated kinase 1/2 (MEK1/2) inhibitor trametinib has shown promising therapeutic effects on melanoma, but its efficacy on colorectal cancer (CRC) is limited. Synthetic lethality arises with a combination of two or more separate gene mutations that causes cell death, whereas individual mutations keep cells alive. This study aimed to identify the genes responsible for resistance to trametinib in CRC cells, using a synthetic lethal short hairpin RNA (shRNA) screening approach...
July 31, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28754154/prognostic-value-of-programmed-death-1-programmed-death-ligand-1-programmed-death-ligand-2-expression-and-cd8-t-cell-density-in-primary-tumors-and-metastatic-lymph-nodes-from-patients-with-stage-t1-4n-m0-gastric-adenocarcinoma
#20
Yuan Gao, Su Li, Dazhi Xu, Shangxiang Chen, Yuchen Cai, Wenqi Jiang, Xinke Zhang, Jin Sun, Kefeng Wang, Boyang Chang, Fenghua Wang, Minghuang Hong
BACKGROUND: Anti-programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) immunotherapy has been proved to be effective on gastric cancer in ongoing clinical trials. However, the value of PD-L1 in predicting responses of patients with gastric cancer to anti-PD-1/PD-L1 immunotherapy is controversial. Some studies suggested that intra- and inter-tumoral heterogeneity of PD-L1 expression might explain the controversy. This study aimed to analyze the expression of PD-L1, PD-L2, and PD-1 as well as CD8(+) T-cell density in primary tumors and lymph nodes from patients with stage T1-4N+M0 gastric adenocarcinoma to explore the heterogeneity of PD-1 signaling pathway molecules...
July 29, 2017: Chinese Journal of Cancer
journal
journal
42277
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"