Read by QxMD icon Read

Journal of Evidence-based Medicine

Yongyan Wang
No abstract text is available yet for this article.
August 10, 2016: Journal of Evidence-based Medicine
Segun Bello
Blinding is an important methodological principle in drug development. This article reviews the functionality of blinding within the context of bias minimizing structures of randomized clinical trials. Blinding is not well understood and not well studied. The risk of bias domain 'blinding' is commonly assumed to be 'low-risk' whenever readers come across randomized clinical trials labelled as 'blinded'. However, empirical evidence has shown that this assumption cannot be taken for granted. The functionality of blinding techniques in preventing bias requires further studies...
August 3, 2016: Journal of Evidence-based Medicine
Ai-Min Wu, Tie-Jun Tong, Xiang-Yang Wang
Lumbar spinal stenosis is caused by the gradual narrowing of spinal canal and compressing of nerve, leading to intermittent claudication, leg pain and walking disability. It is one of the most common spinal disorders in elderly patients (1-3), and is estimated to rise to 64 million elderly adults by the year 2025 (4). How to choose decompression alone or decompression plus fusion is an old and persistent issue (5-7), which was raised again as a hot topic by two recent multicenter RCTs papers published in the same issue of N Engl J Med (8, 9)...
August 1, 2016: Journal of Evidence-based Medicine
Yifei Li, Kaiyu Zhou, Yimin Hua
Transcatheter closure has become one of the alternations of surgical treatment Since 1988. However, cAVB occurred as a threatening incidence of 6.8% after Amplatzer VSD Occluder closure, which was quite higher than the incidence of 1-2% post surgical closure, which leaded this kind of technique was not approved by FDA. In this commentary, we reviewed the publications of cAVB following the device closure, and summarized current data of Modified Amplatzer-type Occluder during long term follow-up. Especially introduced the experiences from China, where this kind of treatment became a routine procedure for VSD children...
August 1, 2016: Journal of Evidence-based Medicine
Wisit Cheungpasitporn, Charat Thongprayoon, Narat Srivali, Priya Vijayvargiya, Carl A Andersen, Wonngarm Kittanamongkolchai, Insara J Jaffer Sathick, Sean M Caples, Stephen B Erickson
OBJECTIVE: The risk of hypertension in adults who regularly take a nap is controversial. The objective of this meta-analysis was to assess the associations between napping and hypertension. METHODS: A literature search was performed using MEDLINE, EMbase and The Cochrane Database of Systematic Reviews from inception through October, 2015. Studies that reported relative risks, odd ratios or hazard ratios comparing the risk of hypertension in individuals who regularly take nap were included...
July 4, 2016: Journal of Evidence-based Medicine
Zhiqiang Hu, Jiajie Yu, Ge Gui, Yuan Chen, Rui Huang, Lucan Jiang, Liang Du, Joey S W Kwong, Youping Li, Lingli Zhang
OBJECTIVE: Cisplatin is one of efficacious medicines for TGCT, but is not in 18(th) WHO EML now. The Union for International Cancer Control recommended cisplatin to the 19(th) WHO EML for TGCT. To evaluate the effectiveness, safety and cost of cisplatin for TGCT according to the requirements of WHO EML Expert Committee, and to provide the evidence whether cisplatin should be included in WHO EML. METHODS: We searched The Cochrane Library, PubMed, EMbase, NHS EED, U...
July 4, 2016: Journal of Evidence-based Medicine
Min Xie, Jianxin Huang, Peng Li, Zhiyan Ou, Jing Hou
OBJECTIVES: We aimed to conduct a pharmacodynamic comparison of rocuronium bromide between patients from the plateau area and from the plain area. METHODS: A total of 104 patients who received laparoscopic cholecystectomy in Sichuan Provincial People's Hospital and Aba Autonomous Prefecture People's Hospital from October 2015 to December 2015 were included in this study. Among them, 46 patients were from the plateau area and 58 were from the plain area. Both groups received total intravenous anesthesia (TIVA) with a dose of 0...
June 23, 2016: Journal of Evidence-based Medicine
Charat Thongprayoon, Wisit Cheungpasitporn, Alexander J Podboy, Erin A Gillaspie, Kevin L Greason, Kianoush B Kashani
OBJECTIVE: The goal of this systematic review was to assess the effects of contrast media volume on transcatheter aortic valve replacement-related acute kidney injury. METHODS: A literature search was performed using Medline, EMbase, the Cochrane Database of Systematic Reviews and from the inception of these databases through December 2015. Studies that reported relative risk, odds ratio, or hazard ratio comparing the risks of acute kidney injury following transcatheter aortic valve replacement in patients who received high contrast media volume, were included...
June 17, 2016: Journal of Evidence-based Medicine
Li Hui Deng, Jun Jie Xiong, Qing Xia
OBJECTIVE: To investigate the advantage between isolated Roux loop pancreaticojejunostomy (IPJ) and conventional pancreaticojejunostomy (CPJ) after pancreaticoduodenectomy (PD). METHODS: Comparative studies on this topic published between January 1976 and April 2015 in PubMed, EMbase, EBSCO, Science Citation Index Expanded and Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library were searched, and selected based on specific inclusion and exclusion criteria...
June 17, 2016: Journal of Evidence-based Medicine
Edward Araujo, Gabriele Tonni, Wellington P Martins
OBJECTIVE: To assess the outcomes of infants followed-up at least 12 months after open and endoscopic fetal surgery for the treatment of spina bifida. METHODS: A searching in The Cochrane Library, LILACS, PubMed and SCOPUS databases for fetal meningomyelocele (MMC) open or endoscopic surgery in humans from 2003 on-wards with follow-up at least 12 months. The rate of the estimated proportions was evaluated by the 95% confidence interval (CI). RESULTS: A total of 19 studies were finally included (17 open and 2 endoscopic surgery)...
June 15, 2016: Journal of Evidence-based Medicine
Stefan G Hofmann, Giovanbattista Andreoli, Joseph K Carpenter, Joshua Curtiss
OBJECTIVE: Some evidence suggests that Hatha yoga might be an effective practice to reduce anxiety. To examine the effect of Hatha yoga on anxiety, we conducted a meta-analysis of relevant studies extracted from PubMed, PsycINFO, the Cochrane Library, and manual searches. METHODS: The search identified 17 studies (11 waitlist controlled trials) totaling 501 participants who received Hatha yoga and who reported their levels of anxiety before and after the practice...
May 20, 2016: Journal of Evidence-based Medicine
Menghuan Song, Hong Guo, Hong Chen, Hao Hu
OBJECTIVE: This research aims to examine the basic and methodological characteristics of anti-cancer drug studies registered on the Chinese Clinical Trial Registry (ChiCTR) and explores the progress of implementation of good clinical practice (GCP) and the challenges it poses for anti-cancer drug research in China. METHODS: The studies from 2007 to 2015 were downloaded from the ChiCTR and those involving anti-cancer drugs with evaluation of the main dimensions. The numerical trend of the studies registered each year was analysed...
May 20, 2016: Journal of Evidence-based Medicine
Adeel S Zubair, Wisit Cheungpasitporn, Stephen B Erickson, Mikel Prieto
OBJECTIVE: The objective of this study is to assess clinical and safety outcomes after laparoscopic nephrectomy with autotransplantation for loin pain-hematuria syndrome (LPHS). METHODS: We conducted telephone interviews using structured questionnaires and retrospectively reviewed data on all patients who underwent laparoscopic nephrectomy with autotransplantation for LPHS between January 2000 and May 2014. RESULTS: A total of 24 laparoscopic nephrectomies with renal autotransplantation of 21 patients with LPHS refractory to conservative medical treatment were reviewed...
May 17, 2016: Journal of Evidence-based Medicine
Jing Tan, Qiao Cao, Guo-Lin He, Yu-Han Cai, Jia-Jie Yu, Xin Sun, You-Ping Li
OBJECTIVE: To compare the effects of misoprostol versus ergometrine-oxytocin for PPH prevention, and provide important evidence to choose optimal agents for preventing PPH in developing countries. METHODS: The Cochrane Central Register of Controlled Trials, PubMed, EMbase, and were searched from inception to 1st January 2016. Two authors independently extracted data and assessed risk of bias of studies according to Cochrane Handbook5.1.0. Meta-analysis was performed using RevMan5...
May 13, 2016: Journal of Evidence-based Medicine
Yuansheng Huang, Zhirong Yang, Jing Wang, Lin Zhuo, Zhixia Li, Siyan Zhan
AIM: To compare the performance of search strategies to retrieve systematic reviews of diagnostic test accuracy from The Cochrane Library. METHODS: Databases of CDSR and DARE in the Cochrane Library were searched for systematic reviews of diagnostic test accuracy published between 2008 and 2012 through nine search strategies. Each strategy consists of one group or combination of groups of searching filters about diagnostic test accuracy. Four groups of diagnostic filters were used...
May 6, 2016: Journal of Evidence-based Medicine
Allen F Shaughnessy, John R Torro, Kara A Frame, Munish Bakshi
BACKGROUND: In the USA, recent changes to oversight of residency training codify the requirements for teaching evidence-based medicine and information mastery (lifelong learning) knowledge, skills, and attitudes. OBJECTIVE: The goal of this project is to determine current requirements for teaching of evidence-based medicine (EBM) and information mastery (IM) in specialty residency education in the USA. METHODS: The project was a qualitative thematic analysis using content analysis...
May 2016: Journal of Evidence-based Medicine
Dang Wei, Kun Tang, Qi Wang, Janne Estill, Liang Yao, Xiaoqin Wang, Yaolong Chen, Kehu Yang
OBJECTIVE: The application of GRADE (Grading of Recommendations Assessment, Development and Evaluation) in SR of animal studies can promote the translation from bench to bedside. We aim to explore the use of GRADE in systematic reviews of animal studies. METHODS: We used a theoretical analysis method to explore the use of GRADE in SR of animal studies and applied in a SR of animal studies. Meanwhile, we presented and discussed our results in two international conferences...
March 15, 2016: Journal of Evidence-based Medicine
Wei Deng, Le Li, Zixia Wang, Xiaonan Chang, Rui Li, Ziye Fang, Dang Wei, Liang Yao, Xiaoqin Wang, Qi Wang, Guanghui An
OBJECTIVE: To evaluate/assess the quality of the Clinical Practice Guidelines (CPGs) of traditional medicine in China. METHODS: We systematically searched the literature databases WanFang Data, VIP, CNKI and CBM for studies published between 1978 and 2012 to identify and select CPGs of traditional medicine. We used the Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument to evaluate these guidelines. RESULTS: A total of 75 guidelines were included, of which 46 guidelines (62%) were on Traditional Chinese Medicine, 19 (25%) on Chinese Integrated Medicine, and 10 (13%) on Uyghur Medicine...
March 15, 2016: Journal of Evidence-based Medicine
Hailong Zhou, Xiaoyan Yang, Sheng Zhao, Xiaoping Pan, Junhong Xu
OBJECTIVE: China is a country that experiences frequent earthquakes and has a high pulmonary tuberculosis (PTB) burden. In this study, we aimed to explore the spatial clustering and risk factors of the reported incidence of PTB before and after the Wenchuan earthquake. METHODS: Data on the location and the demographic, socioeconomic, and health service characteristics of the 181 counties of Sichuan province from 2004 to 2012 were collected. Global and local spatial autocorrelation analyses were performed to explore spatial clustering...
March 11, 2016: Journal of Evidence-based Medicine
Zhongheng Zhang
The results of meta-analysis are usually influenced by characteristics of component trials. These characteristics include but are not limited to sample size, publication language, quality of study design and the number of participating centers. Because systematic review and meta-analysis is considered to be evidence of the highest quality in the era of evidence-based medicine, characteristics that may bias the results of meta-analysis should be fully investigated. Meta-epidemiological study aims to investigate the impact of study design characteristics on treatment effect...
February 9, 2016: Journal of Evidence-based Medicine
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"