Read by QxMD icon Read

Journal of Evidence-based Medicine

Karn Wijarnpreecha, Panadeekarn Panjawatanan, Patompong Ungprasert
OBJECTIVES: Chronic hepatitis C virus (HCV) infection is one of the most common chronic liver diseases. Several risk factors for the progression of liver fibrosis among these patients have been identified. Use of cannabis could be another risk factor, but the results from epidemiological studies remain inconclusive. METHODS: Comprehensive literature review was conducted using MEDLINE and EMBASE databases through December 2017 to identify studies that compared the risk of advanced liver fibrosis among HCV-infected patients who use and who do not use cannabis...
November 5, 2018: Journal of Evidence-based Medicine
Per Lytsy
P-values are often calculated when testing hypotheses in quantitative settings, and low P-values are typically used as evidential measures to support research findings in published medical research. This article reviews old and new arguments questioning the evidential value of P-values. Critiques of the P-value include that it is confounded, fickle, and overestimates the evidence against the null. P-values may turn out falsely low in studies due to random or systematic errors. Even correctly low P-values do not logically provide support to any hypothesis...
November 5, 2018: Journal of Evidence-based Medicine
Wisit Kaewput, Charat Thongprayoon, Mathirut Mungthin, Sarawut Jindarat, Narittaya Varothai, Picha Suwannahitatorn, Ram Rangsin, Michael A Mao, Wisit Cheungpasitporn
BACKGROUND: This study aimed to assess the nationwide trends in optimal diabetic care and complications of elderly type 2 diabetes mellitus (T2DM) patients over a 6-year period in Thailand. METHODS: T2DM patients aged 65 years or older who received medical care at public hospitals in Thailand from 2010 to 2015 were included. The optimal T2DM care in elderly patients was defined as (1) blood pressure (BP) < 140/90, (2) hemoglobin A1C (HbA1c) < 7%, (3) low-density lipoprotein cholesterol (LDL-C) < 100 mg/dL, (4) use of antiplatelet medications, and (5) use of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) in hypertensive patients...
November 5, 2018: Journal of Evidence-based Medicine
Mengqin Zhang, Min Wang, Xiufang Zhao, Jianhua Ren, Jie Xiang, Biru Luo, Jianrong Yao
OBJECTIVE: To assess the incidence rates and risk factors for episiotomy during vaginal childbirth in a Western China context. METHODS: A retrospective hospital-based cohort study was conducted using computerized data of 3721 singleton vaginal deliveries after 28 weeks of gestation. Women who underwent episiotomy were compared with those who did not. RESULTS: The overall prevalence of episiotomy was 44.0% (1636/3721); 52.9% (1458/2756) among primiparas and 18...
August 29, 2018: Journal of Evidence-based Medicine
Ying Luo, Shaomin Zhang, Rongrong Zheng, Lian Xu, Jinhui Wu
BACKGROUND: Depression is an independent risk factor in coronary artery disease (CAD). Our objective was to evaluate the impact of depression on heart rate variability (HRV) in patients with stable CAD. METHODS: This study included patients with a stable CAD who admitted to our hospital in the geriatric medical center from August 2016 to December 2016. All patients agreed to participate in the study and sign informed consent. The study group included 90 CAD patients with a diagnosis of depression and 99 CAD patients without depression...
August 9, 2018: Journal of Evidence-based Medicine
Susan L Norris
The World Health Organization (WHO) is a leading source of trustworthy guidelines in public health, including in emergencies. In addition to standard guidelines produced in preparation for emergency response, WHO has processes and methods for issuing guidelines in the context of urgent public health need, including rapid advice guidelines (production time 2 to 3 months) and health emergency interim guidelines (days to weeks). There are numerous challenges to producing guidelines in response to an emergency in addition to the compressed timeline which necessitates truncating or modifying standard processes...
August 2018: Journal of Evidence-based Medicine
Soontharee Congrete, Maythawee Bintvihok, Charat Thongprayoon, Tarun Bathini, Boonphiphop Boonpheng, Konika Sharma, Ronpichai Chokesuwattanaskul, Narat Srivali, Tanyanan Tanawuttiwat, Wisit Cheungpasitporn
BACKGROUND/OBJECTIVES: Patients with obstructive sleep apnea (OSA) have an increased the risk of developing atrial fibrillation (AF). However, it remains unclear if patients with OSA carry a higher risk of recurrent AF after successful catheter ablation. This meta-analysis was conducted (1) to evaluate the association between OSA and recurrent AF after catheter ablation, and (2) to assess the effect of continuous positive airway pressure (CPAP) on the risk of recurrent AF in patients with OSA...
August 2018: Journal of Evidence-based Medicine
Sang Il Lee, Shabaaz Sandhu, Benjamin Djulbegovic, Rahul S Mhaskar
OBJECTIVE: Spinal anesthesia is the most frequently performed anesthesia for cesarean section. The American Society of Anesthesiology recommends using pencil-point spinal needles (SNs) over cutting-bevel SNs to reduce postdural puncture headache (PDPH) in their practice guidelines for obstetric anesthesia. However, there is no meta-analysis addressing the impact of the type of SNs on PDPH among women undergoing Cesarean section surgery. METHODS: We conducted a systematic review and meta-analysis including randomized controlled trials comparing the incidence of PDPH of pencil-point SNs with cutting-bevel SNs in patients undergoing Cesarean section with spinal anesthesia...
August 2018: Journal of Evidence-based Medicine
Boonphiphop Boonpheng, Charat Thongprayoon, Wisit Cheungpasitporn
OBJECTIVE: Several studies have demonstrated that end-stage renal disease (ESRD) patients on dialysis are at higher risk for cerebrovascular events, especially those on hemodialysis. However, the risk of stroke in patients on peritoneal dialysis (PD) compared to those on hemodialysis (HD) remains unclear. We performed this meta-analysis to assess the risks of stroke in ESRD patients on PD compared to HD. METHODS: A systematic review was conducted using MEDLINE, EMBASE, Cochrane databases from inception through January 2018 to identify studies that evaluated the risks of stroke (all types of stroke, ischemic stroke or hemorrhagic stroke) in ESRD patients on different dialysis modalities...
August 2018: Journal of Evidence-based Medicine
Bei Pan, Yiting Wu, Qingxia Yang, Long Ge, Caiyun Gao, Yangqin Xun, Jinhui Tian, Guowu Ding
OBJECTIVE: To comprehensively compare the differences between major dietary patterns in improving glycemic control, cardiovascular risk, and weight loss for patients with type 2 diabetes. METHOD: We systematically searched PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials (CENTRAL) to identify randomized controlled trials (RCTs) that compared the efficacy of Mediterranean, low-carbohydrate, and/or low-fat dietary patterns for patients with type 2 diabetes...
August 1, 2018: Journal of Evidence-based Medicine
Chengwu Jin, Xiangbing Deng, Yan Li, Wanbin He, Xuyang Yang, Jian Liu
OBJECTIVE: With neoadjuvant therapy increasingly used in advanced rectal cancer, the lymph node ratio (LNR) has been strongly considered to indicate cancer-specific survival in recent years, and a comprehensive evaluation of a large number of studies is deficient. The objective of our study is to pool enough eligible studies to assess the relationship between LNR and prognosis of advanced rectal cancer after neoadjuvant therapy. METHODS: A systematic search was done in the PubMed and EmBase databases (through 1 March 2017) that reported LNR in colorectal cancer after neoadjuvant therapy...
August 2018: Journal of Evidence-based Medicine
Astrid Austvoll-Dahlgren, Marit Johansen
BACKGROUND: Shared decision-making is a central element of evidence-based practice (EBP). Training in EBP has traditionally focused on providers, but there is an increasing interest in developing such educational resources for patients. The aim of this study is to explore the views of patient representatives attending a workshop in EBP. METHODS: We conducted three focus groups with participants attending EBP workshops in 2013, 2014, and 2015. We used the framework method for content analysis...
August 2018: Journal of Evidence-based Medicine
Daniel Erlewein, Tommaso Bruni, Mariacarla Gadebusch Bondio
OBJECTIVE: In 1983, McIntyre and Popper underscored the need for more openness in dealing with errors in medicine. Since then, much has been written on individual medical errors. Furthermore, at the beginning of the 21st century, researchers and medical practitioners increasingly approached individual medical errors through health information technology. Hence, the question arises whether the attention of biomedical researchers shifted from individual medical errors to health information technology...
August 2018: Journal of Evidence-based Medicine
Atefeh Ghanbari, Pardis Rahmatpour, Fateme Jafaraghaee, Ehsan Kazemnejad, Malahat Khalili
OBJECTIVE: Nurses play an effective role in diabetic foot care and they should know the best evidence. In this way, implementations according evidence-based clinical practice guidelines have positive effects on nurses' practice and patient outcomes. The objective of this study was quality assessment of diabetic foot ulcer clinical practice guidelines. METHODS: Evidence about nursing care in diabetic foot ulcer in last 5 years was searched and categorized based on nursing diagnosis (ND) and evidence levels and was finally designed as a guideline...
August 2018: Journal of Evidence-based Medicine
Frank Peinemann, Alexander Michael Labeit
OBJECTIVE: Proper interpretation of survival data of clinical cancer studies may be difficult and pitfalls related to the nature of Kaplan-Meier analyses might end up in mistaken inferences. The purpose of the present work is to raise awareness of those pitfalls and to prevent errors in future studies. STUDY DESIGN AND SETTING: While evaluating a randomized controlled trial, we came across some issues possibly associated with misinterpreting survival data. We thoroughly reviewed the reporting of survival analyses, statistical approaches, baseline characteristics, and choice of primary end point...
August 2018: Journal of Evidence-based Medicine
Sheyu Li, Chuan Yu, Yun Li, Qianrui Li, Rui Zhang, Qingtao Hou, Tao Zheng, Yi Ma, Miye Wang, Na Su, Ting Wu, Zhiwen Liu, Xia Sheng, Nan Li, Guanjian Liu, Yong Huang, Ting Xu, Xin Sun, Haoming Tian
AIM: To describe the characteristics of inpatients with diabetes in a tertiary hospital in China using an electronic medical record (EMR)-based database. METHODS: We identified the medical records of all patients with diabetes from nonpediatric departments of West China Hospital, Sichuan University (from February 2009 to December 2013), and extracted information on demographic, diagnosis, discharge outcome, department of discharge, laboratory test, and prescription from the EMR system...
August 2018: Journal of Evidence-based Medicine
Chang Xu, Yuming Niu, Junyi Wu, Huiyun Gu, Chao Zhang
OBJECTIVE: To compare and analyze the characteristics and functions of software applications for network meta-analysis (NMA). METHODS: PubMed, EMbase, The Cochrane Library, the official websites of Bayesian inference Using Gibbs Sampling (BUGS), Stata and R, and Google were searched to collect the software and packages for performing NMA; software and packages published up to March 2016 were included. After collecting the software, packages, and their user guides, we used the software and packages to calculate a typical example...
August 2018: Journal of Evidence-based Medicine
Yali Fu, Shuwei Zha, Nianqing Lü, Haoqin Xu, Xuening Zhang, Wenhui Shi, Ji Zha
OBJECTIVE: The objective of this study was to review the carrier frequencies of hearing loss gene variants, such as GJB2, SLC26A4, and MT-RNR1 in newborns of China. DESIGN: PubMed, Embase, BioCentral, CNKI, WanFang, and VIP databases were used for searching relevant literature studies published during the period of January 2007 and January 2016. Meta-analysis was performed by using the R software. The estimated rate and its 95% confidence intervals (CI) of the relevant indexes in newborns were collected and calculated using a fixed-effects model or a random-effects model when appropriate...
July 2, 2018: Journal of Evidence-based Medicine
Wenwen Chen, Jiajie Yu, Huan Tao, Yujia Cai, Youping Li, Xin Sun
OBJECTIVE: To assess the impact of motherwort injection alone or combined with oxytocin for preventing postpartum hemorrhage in pregnant women with caesarean section. METHODS: A systematic review and meta-analysis of randomized trials were performed. PubMed, EMbase, The Cochrane Central Register of Controlled Trials (CENTRAL), Chinese database Sino-Med, Chinese National Knowledge Infrastructure Database (CNKI), VIP Chinese Science and Technique Journals Database, WanFang, and ClinicalTrials...
June 7, 2018: Journal of Evidence-based Medicine
Ariel R Choi, Paul B Greenberg
OBJECTIVE: To systematically review the comparative effectiveness of patient education strategies in cataract surgery. METHODS: A comprehensive literature search of five electronic databases was conducted for randomized controlled trials (RCTs) studying the efficacy of educational interventions for cataract surgery patients. Peer-reviewed articles published in English were considered for inclusion without restriction limits on publication date. General study characteristics, measurement methodologies, and outcome measures were narratively synthesized...
May 2018: Journal of Evidence-based Medicine
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"