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IEEE Reviews in Biomedical Engineering

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https://www.readbyqxmd.com/read/27411228/state-of-the-art-for-deep-brain-stimulation-therapy-in-movement-disorders-a-clinical-and-technological-perspective
#1
Aparna Wagle Shukla, Michael S Okun
Deep brain stimulation (DBS) therapy is a widely used brain surgery that can be applied for many neurological and psychiatric disorders. DBS is American Food and Drug Administration approved for medication refractory Parkinson's disease, essential tremor and dystonia. Although DBS has shown consistent success in many clinical trials, the therapy has limitations and there are well-recognized complications. Thus, only carefully selected patients are ideal candidates for this surgery. Over the last two decades, there have been significant advances in clinical knowledge on DBS...
2016: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/27337725/mathematical-models-of-contrast-transport-kinetics-for-cancer-diagnostic-imaging-a-review
#2
Simona Turco, Hessel Wijkstra, Massimo Mischi
Angiogenesis plays a fundamental role in cancer growth and the formation of metastasis. Novel cancer therapies aimed at inhibiting angiogenic processes and/or disrupting angiogenic tumor vasculature are currently being developed and clinically tested. The need for earlier and improved cancer diagnosis, and for early evaluation and monitoring of therapeutic response to angiogenic treatment, have led to the development of several imaging methods for in vivo noninvasive assessment of angiogenesis. The combination of dynamic contrast-enhanced imaging with mathematical modeling of the contrast agent kinetics enables quantitative assessment of the structural and functional changes in the microvasculature that are associated with tumor angiogenesis...
2016: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/27337724/review-of-the-experimental-background-and-implementation-of-computational-models-of-the-ocular-lens-microcirculation
#3
Ho-Ting D Wu, Paul J Donaldson, Ehsan Vaghefi
Our sense of vision is critically dependent on the clarity of the crystalline lens. The most common cause of transparency loss in the lens is age-related nuclear cataract, which is due to accumulative oxidative damage to this tissue. Since the ocular lens is an avascular tissue, it has to maintain its physiological homeostasis and antioxidant levels using a system of water microcirculation. This system has been experimentally imaged in animal lenses using different modalities. Based on these data, computational models have been developed to predict the properties of this system in human lenses and its changes due to aging...
2016: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/27333610/a-review-of-engineering-approaches-for-lymphedema-detection
#4
Karina Rincon, Pratikkumar Shah, Jessica Ramella-Roman, Shekhar Bhansali
Edema is a condition characterized by excessive swelling of a tissue due to an abnormal accumulation of interstitial fluid in the subcutaneous tissue. More specifically, disruption of the lymphatic system causes what is known as lymphedema. This condition is commonly seen in breast cancer survivors postradiotherapy treatment, chemotherapy, and surgeries; this population has shown high risk of developing lymphedema in the limbs. Throughout the years, several techniques have been developed and implemented for the detection and measurement of lymphedema, including techniques to measure the diseased limb volume, electrical techniques to measure the water content in tissues, and optical techniques to measure either tissue absorbance or limb volume...
2016: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/27323373/treating-total-occlusions-applying-force-for-recanalization
#5
Aimee Sakes, Evelyn Regar, Jenny Dankelman, Paul Breedveld
GOAL: The aim of this review was to analyze and review the state of the art devices for the endovascular treatment of chronic and acute total occlusions in the different vascular beds (coronary, peripheral, carotid, and intracranial arteries) based on the forces exerted on the occlusion during treatment. METHODS: The literature search was executed in the databases of Scopus and Espacenet. Overall, 120 patents and 49 articles have been reviewed and categorized. RESULTS: The identified treatment tools were divided into three treatment modalities: compression, resection, and conversion...
2016: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/27249837/review-on-lithotripsy-and-cavitation-in-urinary-stone-therapy
#6
Morteza Ghorbani, Ozlem Oral, Sinan Ekici, Devrim Gozuacik, Ali Kosar
Cavitation is the sudden formation of vapor bubbles or voids in liquid media and occurs after rapid changes in pressure as a consequence of mechanical forces. It is mostly an undesirable phenomenon. Although the elimination of cavitation is a major topic in the study of fluid dynamics, its destructive nature could be exploited for therapeutic applications. Ultrasonic and hydrodynamic sources are two main origins for generating cavitation. The purpose of this review is to give the reader a general idea about the formation of cavitation phenomenon and existing biomedical applications of ultrasonic and hydrodynamic cavitation...
2016: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/27071194/upper-limb-robotic-exoskeletons-for-neurorehabilitation-a-review-on-control-strategies
#7
Tommaso Proietti, Vincent Crocher, Agnes Roby-Brami, Nathanael Jarrasse
Since the late 1990s, there has been a burst of research on robotic devices for poststroke rehabilitation. Robot-mediated therapy produced improvements on recovery of motor capacity; however, so far, the use of robots has not shown qualitative benefit over classical therapist-led training sessions, performed on the same quantity of movements. Multidegree-of-freedom robots, like the modern upper-limb exoskeletons, enable a distributed interaction on the whole assisted limb and can exploit a large amount of sensory feedback data, potentially providing new capabilities within standard rehabilitation sessions...
2016: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/27071193/computer-vision-guided-human-pulse-rate-estimation-a-review
#8
Arindam Sikdar, Santosh Kumar Behera, Debi Prosad Dogra
Human pulse rate (PR) can be estimated in several ways, including measurement instruments that directly count the PR through contact- and noncontact-based approaches. Over the last decade, computer-vision-assisted noncontact-based PR estimation has evolved significantly. Such techniques can be adopted for clinical purposes to mitigate some of the limitations of contact-based techniques. However, existing vision-guided noncontact-based techniques have not been benchmarked with respect to a challenging dataset...
2016: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/27008673/movement-quantification-in-neurological-diseases-methods-and-applications
#9
Maria do Carmo Vilas-Boas, Joao Paulo Silva Cunha
The movement of the human body offers neurologists important clues for the diagnosis and follow-up of many neurological diseases. The typical diagnosis approach is accomplished through simple observation of movements of interest (MOI) associated with a specific neurological disease. This approach is highly subjective because it is mainly based on qualitative evaluation of MOIs. Quantitative movement techniques are then obvious diagnosis-aid systems to approach these cases. Nevertheless, the use of motion quantification techniques in these pathologies is still relatively rare...
2016: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/26960228/haptics-in-robot-assisted-surgery-challenges-and-benefits
#10
Nima Enayati, Elena De Momi, Giancarlo Ferrigno
Robotic surgery is transforming the current surgical practice, not only by improving the conventional surgical methods but also by introducing innovative robot-enhanced approaches that broaden the capabilities of clinicians. Being mainly of man-machine collaborative type, surgical robots are seen as media that transfer pre- and intraoperative information to the operator and reproduce his/her motion, with appropriate filtering, scaling, or limitation, to physically interact with the patient. The field, however, is far from maturity and, more critically, is still a subject of controversy in medical communities...
2016: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/26929060/laser-speckle-imaging-to-monitor-microvascular-blood-flow-a-review
#11
Pedro G Vaz, Anne Humeau-Heurtier, Edite Figueiras, Carlos Correia, Joao Cardoso
Laser speckle is a complex interference phenomenon that can easily be understood, in concept, but is difficult to predict mathematically, because it is a stochastic process. The use of laser speckle to produce images, which can carry many types of information, is called laser speckle imaging (LSI). The biomedical applications of LSI started in 1981 and, since then, many scientists have improved the laser speckle theory and developed different imaging techniques. During this process, some inconsistencies have been propagated up to now...
2016: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/26887012/quantitative-laughter-detection-measurement-and-classification-a-critical-survey
#12
Sarah Cosentino, Salvatore Sessa, Atsuo Takanishi
The study of human nonverbal social behaviors has taken a more quantitative and computational approach in recent years due to the development of smart interfaces and virtual agents or robots able to interact socially. One of the most interesting nonverbal social behaviors, producing a characteristic vocal signal, is laughing. Laughter is produced in several different situations: in response to external physical, cognitive, or emotional stimuli; to negotiate social interactions; and also, pathologically, as a consequence of neural damage...
2016: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/26849872/treatment-of-the-partial-hand-amputation-an-engineering-perspective
#13
Ilario Imbinto, Carlo Peccia, Marco Controzzi, Andrea Giovanni Cutti, Angelo Davalli, Rinaldo Sacchetti, Christian Cipriani
Partial hand amputation is perhaps the most frequent amputation level, worldwide. Although its annual incidence in western countries is roughly 1:18‚ÄČ000 inhabitants, the treatments of partial hand amputations have modestly progressed so far. We have identified three main limitation factors to this progress: 1) the wide range of anatomical and functional presentations, which makes difficult to find standardized and scalable solutions; 2) the technological complexity in replacing the motor and sensory function of a lost digit in the size of a digit; and 3) the fact that a partial hand can be functionally successful mostly when it restores a lost opposition movement, i...
2016: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/26829803/magnetic-surgical-instruments-for-robotic-abdominal-surgery
#14
Florence Leong, Nicolo Garbin, Christian Di Natali, Alireza Mohammadi, Dhan Thiruchelvam, Denny Oetomo, Pietro Valdastri
This review looks at the implementation of magnetic-based approaches in surgical instruments for abdominal surgeries. As abdominal surgical techniques advance toward minimizing surgical trauma, surgical instruments are enhanced to support such an objective through the exploration of magnetic-based systems. With this design approach, surgical devices are given the capabilities to be fully inserted intraabdominally to achieve access to all abdominal quadrants, without the conventional rigid link connection with the external unit...
2016: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/26742143/robust-nucleus-cell-detection-and-segmentation-in-digital-pathology-and-microscopy-images-a-comprehensive-review
#15
Fuyong Xing, Lin Yang
Digital pathology and microscopy image analysis is widely used for comprehensive studies of cell morphology or tissue structure. Manual assessment is labor intensive and prone to interobserver variations. Computer-aided methods, which can significantly improve the objectivity and reproducibility, have attracted a great deal of interest in recent literature. Among the pipeline of building a computer-aided diagnosis system, nucleus or cell detection and segmentation play a very important role to describe the molecular morphological information...
2016: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/26292162/a-review-of-locomotion-systems-for-capsule-endoscopy
#16
REVIEW
Lejie Liu, Shahrzad Towfighian, Amine Hila
Wireless capsule endoscopy for gastrointestinal (GI) tract is a modern technology that has the potential to replace conventional endoscopy techniques. Capsule endoscopy is a pill-shaped device embedded with a camera, a coin battery, and a data transfer. Without a locomotion system, this capsule endoscopy can only passively travel inside the GI tract via natural peristalsis, thus causing several disadvantages such as inability to control and stop, and risk of capsule retention. Therefore, a locomotion system needs to be added to optimize the current capsule endoscopy...
2015: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/26011892/a-review-of-wavelet-transform-time-frequency-methods-for-nirs-based-analysis-of-cerebral-autoregulation
#17
REVIEW
Paul S Addison
Near-infrared spectroscopy (NIRS) has been proposed as a suitable technique for the analysis of cerebral autoregulation as it provides a simpler acquisition methodology and more artifact-free signal. A number of sophisticated wavelet transform methods have recently emerged to quantify the cerebral autoregulation mechanism using NIRS and blood pressure signals. These provide an enhanced partitioning of signal information via the time-frequency plane, which facilitates improved extraction of the components of interest...
2015: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/25993705/oscillometric-blood-pressure-estimation-past-present-and-future
#18
REVIEW
Mohamad Forouzanfar, Hilmi R Dajani, Voicu Z Groza, Miodrag Bolic, Sreeraman Rajan, Izmail Batkin
The use of automated blood pressure (BP) monitoring is growing as it does not require much expertise and can be performed by patients several times a day at home. Oscillometry is one of the most common measurement methods used in automated BP monitors. A review of the literature shows that a large variety of oscillometric algorithms have been developed for accurate estimation of BP but these algorithms are scattered in many different publications or patents. Moreover, considering that oscillometric devices dominate the home BP monitoring market, little effort has been made to survey the underlying algorithms that are used to estimate BP...
2015: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/25974948/electrical-and-mechanical-strategies-to-enable-cardiac-repair-and-regeneration
#19
REVIEW
Hung Cao, Bong Jin Kang, Chia-An Lee, K Kirk Shung, Tzung K Hsiai
Inadequate replacement of lost ventricular myocardium from myocardial infarction leads to heart failure. Investigating the regenerative capacity of mammalian hearts represents an emerging direction for tissue engineering and cell-based therapy. Recent advances in stem cells hold promise to restore cardiac functions. However, embryonic or induced pluripotent stem cell-derived cardiomyocytes lack functional phenotypes of the native myocardium, and transplanted tissues are not fully integrated for synchronized electrical and mechanical coupling with the host...
2015: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/25955851/review-of-robotic-technology-for-stereotactic-neurosurgery
#20
REVIEW
Carlos Faria, Wolfram Erlhagen, Manuel Rito, Elena De Momi, Giancarlo Ferrigno, Estela Bicho
The research of stereotactic apparatus to guide surgical devices began in 1908, yet a major part of today's stereotactic neurosurgeries still rely on stereotactic frames developed almost half a century ago. Robots excel at handling spatial information, and are, thus, obvious candidates in the guidance of instrumentation along precisely planned trajectories. In this review, we introduce the concept of stereotaxy and describe a standard stereotactic neurosurgery. Neurosurgeons' expectations and demands regarding the role of robots as assistive tools are also addressed...
2015: IEEE Reviews in Biomedical Engineering
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