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American Journal of Rhinology & Allergy

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https://www.readbyqxmd.com/read/29785855/optimizing-protein-harvest-from-nasal-brushings-for-determining-local-allergy-responses
#1
Erin C Saricilar, Aneeza Hamizan, Raquel Alvarado, Janet Rimmer, William Sewell, Jessica Tatersall, Henry P Barham, Richard Harvey
Background Rhinitis is a highly prevalent yet often misdiagnosed condition. Patients who have local allergic rhinitis are regularly mislabeled as having a nonallergic etiology. Thus, a highly accurate, reproducible, and noninvasive assessment, which can be performed quickly and with minimal discomfort to the patient, is required. Objective The aim of this research was to identify the efficiency of various nasal brushes as tools for harvest and collection of epithelial proteins and its suitability for identification of rhinitis...
May 22, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29781286/medical-therapy-versus-balloon-sinus-dilation-in-adults-with-chronic-rhinosinusitis-merlot-12-month-follow-up
#2
J Pablo Stolovitzky, Neelesh Mehendale, Keith E Matheny, William J Brown, Anthony A Rieder, Douglas R Liepert, Ewen Tseng, Andrew Gould
Background Chronic rhinosinusitis (CRS) is a devastating disease affecting nearly 30 million people in the United States. An interim analysis of data from the present study suggested that, in patients who had previously failed medical therapy, balloon sinus dilation (BSD) plus medical management (MM) provides a significant improvement in the quality of life (QOL) at 24 weeks postprocedure compared to MM alone. Objective The primary objective of this final analysis was to evaluate the durability of treatment effects through the 52-week follow-up...
May 21, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29781284/opioid-prescription-among-sinus-surgeons
#3
Khashayar Arianpour, Brandon Nguyen, Brian Yuhan, Peter F Svider, Jean Anderson Eloy, Adam J Folbe
Background Misuse and diversion of opioids have contributed to the U.S. opioid crisis, making an understanding of specialty-specific and procedure-specific trends essential. Objective The objective of this analysis was to evaluate nationwide trends in opioid prescribing patterns among sinus surgeons performing functional endoscopic sinus surgery and maxillary sinus balloon dilation, specifically examining factors associated with variations. Methods High-volume sinus surgeons were identified through the Centers for Medicare and Medicaid Services database and cross-referenced against prescriptions to Medicare Part D beneficiaries during 2013 through 2015...
May 21, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29774747/hypertonic-saline-versus-isotonic-saline-nasal-irrigation-systematic-review-and-meta-analysis
#4
Dichapong Kanjanawasee, Kachorn Seresirikachorn, Wirach Chitsuthipakorn, Kornkiat Snidvongs
Background Saline nasal lavage is one of the treatments of sinonasal diseases. Evidence from basic research favors hypertonic saline (HS) over isotonic saline (IS) for mucociliary clearance, but evidence from clinical studies is controversial. Conversely, HS may carry greater side effects. Objective To compare the effects of HS and IS nasal irrigation in treating sinonasal diseases. Methods Systematic search with Ovid MEDLINE, Scopus, PubMed, Google Scholar, and Manual additional sources was conducted. Randomized controlled trials comparing HS with IS nasal irrigation in treating any sinonasal diseases, including rhinitis and rhinosinusitis, were included...
May 18, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29754498/axonal-guidance-signaling-pathway-is-suppressed-in-human-nasal-polyps
#5
Dawei Wu, Sarina K Mueller, Angela L Nocera, Kristen Finn, Towia A Libermann, Benjamin S Bleier
Background Dysfunctional innervation might contribute to the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP), but the state of the axonal outgrowth signaling in CRSwNP is unknown. The purpose of this study was to explore the axonal outgrowth pathway-related protein expression in CRSwNP. Methods Institutional review board approved study in which tissue proteomes were compared between control and CRSwNP patients (n = 10/group) using an aptamer-based proteomic array and confirmed by whole transcriptomic analysis...
May 14, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29745245/endoscopic-powered-dacryocystorhinostomy-without-stenting-long-term-outcomes-of-120-procedures
#6
Ejder Ciğer, Mustafa K Balci, Seçil Arslanoğlu, Erdem Eren
Background The necessity of silicone stenting in endoscopic dacryocystorhinostomy (DCR) procedures is a controversial subject in the literature. Objective The purpose of the present study is to assess the long-term anatomical and functional outcomes of endoscopic-powered DCR (EP-DCR) without stenting or mucosal flaps. Methods One hundred twenty EP-DCR procedures were performed in 107 patients. Anatomical success was defined as a patent ostium on irrigation and functional success as free flow of dye from the ostium and resolution of epiphora...
May 10, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29745243/bevacizumab-for-epistaxis-in-hereditary-hemorrhagic-telangiectasia-an-evidence-based-review
#7
Ashleigh A Halderman, Matthew W Ryan, Bradley F Marple, Raj Sindwani, Douglas D Reh, David M Poetker
Objective Epistaxis is a primary complaint in 90% to 96% of patients with hereditary hemorrhagic telangiectasia (HHT). Numerous surgical and medical treatments aim to decrease the frequency and severity of epistaxis in this patient population. Bevacizumab is a recombinant, humanized monoclonal antibody to vascular endothelial growth factor, an angiogenic factor elevated in HHT. It has been used in several forms to treat epistaxis in HHT but thus far, evidence-based recommendations are limited. Study Design Systematic review with evidence-based recommendations...
May 10, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29741096/clinical-predictors-of-frontal-ostium-restenosis-after-draf-3-procedure-for-refractory-chronic-rhinosinusitis
#8
Xiaoqing Zhang, Ting Ye, Zhenxiao Huang, Qian Huang, Junfang Xian, Jing Li, Bing Zhou
Background The Draf 3 procedure has been demonstrated to be effective in the treatment of refractory frontal sinus disease. A variety of clinical factors may contribute to the change of frontal neo-ostium (FNO) area after this procedure. Imaging plays a vital role in the evaluation and follow-up after surgery and provides useful prognostic information. Objectives (1) To investigate the influence of local anatomic factors on FNO after a Draf 3 procedure by radiological measurements on imaging software and (2) to explore other predictive factors of FNO restenosis...
May 9, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29732935/use-of-autologous-fat-grafts-for-the-endoscopic-reconstruction-of-skull-base-defects-indications-outcomes-and-complications
#9
Kent Lam, Amber U Luong, William C Yao, Martin J Citardi
Background The use of abdominal free fat is a traditional surgical method for the repair and reconstruction of the anterior skull base. Our objective is to assess the outcomes associated with the autologous fat graft to endoscopically repair anterior skull base defects at a single tertiary care center. Methods All patients, who underwent endoscopic skull base repair utilizing abdominal free fat from September 2009 to June 2016, were included for retrospective chart review. Evaluated outcome measurements included (1) the successful closure of preoperative and intraoperative cerebrospinal fluid (CSF) leaks and (2) complications at both donor and recipient graft sites during the postoperative periods...
May 7, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29732927/nasal-endoscopy-billing-patterns-a-survey-of-the-american-rhinologic-society
#10
Abtin Tabaee, Charles A Riley, Seth M Brown, Edward D McCoul
Introduction Nasal endoscopy (NE) is an essential element of office-based clinical rhinology, including the evaluation of chronic rhinosinusitis. Despite the presence of guidelines, variability exists regarding coding and billing for NE especially with regard to inclusion of evaluation and management (E&M) codes and use of the 25 modifier. The goal of this survey was to assess the billing patterns for NE among American Rhinologic Society (ARS) members. Methods An invitation to participate in a web-based survey was electronically sent to all ARS members...
May 7, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29683003/assessment-of-a-lateral-nasal-wall-block-technique-for-endoscopic-sinus-surgery-under-local-anesthesia
#11
Grace M Scott, Chris Diamond, Damian C Micomonaco
Introduction With increasingly limited operative resources and patient desires for minimally invasive procedures, there is a trend toward local endoscopic procedures being performed in the outpatient clinic setting. However, there remain limited data supporting a technique to adequately anesthetize the lateral nasal wall and provide patient comfort during these procedures. The objective of this study is to assess the efficacy of a novel lateral nasal wall block for use in office-based endoscopic sinus surgery...
April 23, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29682983/long-term-clinical-outcomes-of-aspirin-desensitization-with-continuous-daily-aspirin-therapy-in-aspirin-exacerbated-respiratory-disease
#12
Kristen M Walters, Jeremy D Waldram, Katharine M Woessner, Andrew A White
Background Aspirin-exacerbated respiratory disease (AERD), also known as Samter's triad or aspirin (ASA)-intolerant asthma, affects 7% of asthmatics and has a higher prevalence in those with chronic rhinosinusitis and concomitant nasal polyposis. ASA desensitization with daily ASA therapy is a uniquely beneficial treatment for this disease entity and has been shown to have a significant impact on symptom scores, polyp disease, and need for systemic corticosteroids. However, no long-term studies have demonstrated whether or not ASA therapy remains safe and beneficial for these patients beyond 5-10 years...
April 23, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29676185/blood-eosinophil-and-basophil-values-before-and-after-surgery-for-eosinophilic-type-sinonasal-polyps
#13
Giuseppe Brescia, Daniela Parrino, Claudia Zanotti, Giulia Tealdo, Umberto Barion, Paolo Sfriso, Gino Marioni
Background Blood eosinophil and basophil levels have recently been considered for the purpose of endotyping chronic rhinosinusitis with nasal polyps (CRSwNP). Histologically, eosinophilic-type CRSwNPs have been associated with high recurrence rates after treatment. Objective The present study was the first to compare blood eosinophil and basophil counts in eosinophilic-type CRSwNP patients before and after endoscopic sinus surgery. Methods The study concerned 79 consecutive patients with histologically confirmed eosinophilic-type CRSwNP treated with endoscopic sinus surgery...
May 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29676168/transnasal-endoscopic-sphenopalatine-artery-ligation-compared-with-embolization-for-intractable-epistaxis-a-long-term-analysis
#14
G de Bonnecaze, Y Gallois, F Bonneville, S Vergez, B Chaput, E Serrano
Background Transnasal endoscopic sphenopalatine artery ligation (TESPAL) and selective embolization both provide excellent treatment success rate in the management of intractable epistaxis. Few long-term studies comparing these approaches have been previously published. Recommendations often present these techniques as alternatives, but there is no clear consensus. Objective The purpose of this study was to evaluate and compare the clinical efficacy of sphenopalatine artery ligation versus embolization to control intractable epistaxis...
May 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29660995/diagnostic-value-of-nasal-cytology-in-chronic-rhinosinusitis-assessed-by-a-liquid-based-cytological-technique
#15
Wenyu She, Jun Yang, Chengshuo Wang, Luo Zhang
Back ground: Nasal cytology has generally been employed as a useful diagnostic tool in the differentiation of rhinopathies. Objective The aim of this study was to assess the extent and diagnostic value of inflammation of nasal and paranasal sinus mucosa in chronic rhinosinusitis patients by employing a combination of nasal brushings and a liquid-based cytological technique. Methods Forty-eight patients with chronic sinusitis and 20 control subjects without any sign of sinusitis undergoing endoscopic surgery, although not all underwent endoscopic sinus surgery, were recruited to the study...
May 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29660990/novel-radiographic-assessment-of-the-cribriform-plate
#16
Kimia G Ganjaei, Zachary M Soler, Elliott D Mappus, Robert J Taylor, Mitchell L Worley, Jennifer K Mulligan, Jose L Mattos, Nicholas R Rowan, Guilherme J M Garcia, Judy R Dubno, Mark A Eckert, Lois J Matthews, Rodney J Schlosser
Background The cribriform plate (CP) is a common site of spontaneous cerebrospinal fluid (SCSF) leaks. Radiographic assessment of the anterior and lateral skull base has shown thinner bone in patients with SCSFs; however, prior assessment of the CP has required postmortem cadaver dissection. Objective To develop novel radiographic techniques to assess the anatomy of the CP. Methods Computed tomography (CT) scans were performed on cadaveric specimens. Bone density and anatomy of a predefined volume of interest of the posterior CP were assessed by two independent reviewers...
May 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29649893/a-three-year-course-of-house-dust-mite-sublingual-immunotherapy-appears-effective-in-controlling-the-symptoms-of-allergic-rhinitis
#17
Silviya M Novakova, Plamena I Novakova, Plamen H Yakovliev, Maria T Staevska, Nonka G Mateva, Teodora D Dimcheva, Jivko L Peichev
Background Allergic rhinitis is the most common allergic disorder. Although the management of the disease is successful in many patients, based on guidelines, some of them remain with symptoms uncontrolled with pharmacotherapy. Presently, there is no substantiated information on the control of allergic rhinitis in patients who underwent sublingual immunotherapy. Objective The purpose of this prospective follow-up study was to assess the control of allergic rhinitis in adults after a three-year course of house dust mite sublingual immunotherapy...
May 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29649892/a-pilot-comparison-between-caregiver-s-and-patient-s-perceived-quality-of-life-in-chronic-rhinosinusitis
#18
Katherine N Adams, Douglas Farquhar, Brent A Senior, Brian D Thorp, Adam M Zanation, Charles S Ebert
Introduction Chronic rhinosinusitis negatively impacts a patient's quality of life, but current studies only address the patient's perception of their disease. Caregivers living with the patient may have an alternative perception of the severity of the quality of life disturbance that patient's experience with chronic rhinosinusitis. Methods This was a prospective cohort study that enrolled patients with a confirmed chronic rhinosinusitis diagnosis who presented to clinic with a caregiver. At the initial visit, patients completed a Rhinosinusitis Disability Index...
May 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29649889/endoscopic-resection-of-sinonasal-inverted-papillomas-systematic-review-and-meta-analysis
#19
John K Goudakos, Sarantis Blioskas, Angelos Nikolaou, Konstantinos Vlachtsis, Peter Karkos, Konstantinos D Markou
Background Pure endoscopic surgery (functional endoscopic sinus surgery) has been increasingly replacing external approaches in the management of sinonasal inverted papillomas. Objective To analyze and compare the effectiveness of pure endoscopic procedure with external or combined procedures to paranasal inverted papillomas, including the experience from two institutions in North Greece, over a 20-year period. Methods Systematic literature searches of MEDLINE (1952-2016), EMBASE (1974-2016), and the Cochrane Central Register of Controlled Trials...
May 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29649887/clinical-effect-of-endoscopic-vidian-neurectomy-on-bronchial-asthma-outcomes-in-patients-with-coexisting-refractory-allergic-rhinitis-and-asthma
#20
Jingang Ai, Zuozhong Xie, Xiang Qing, Wei Li, Honghui Liu, Tiansheng Wang, Guolin Tan
Background The prevalence of both allergic rhinitis and bronchial asthma is high throughout the world; their mutual influence on each other has been documented in many studies. However, studies regarding surgical intervention are limited. Objective To evaluate the clinical significance of endoscopic vidian neurectomy on bronchial asthma outcomes in patients with coexisting refractory allergic rhinitis and asthma. Methods A total of 109 patients with moderate to severe persistent intractable allergic rhinitis and mild/moderate asthma were allocated to the bilateral endoscopic vidian neurectomy group (group 1) or conservative medication group (group 2) according to the patients' self-selection...
May 2018: American Journal of Rhinology & Allergy
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