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American Journal of Rhinology & Allergy

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https://www.readbyqxmd.com/read/29070186/using-the-nasoseptal-flap-for-reconstruction-after-endoscopic-debridement-of-radionecrosis-in-nasopharyngeal-carcinoma
#1
(no author information available yet)
BACKGROUND: Radionecrosis is a complication of nasopharyngeal carcinoma (NPC) that is difficult to treat. Endoscopic debridement is the first-line treatment for radionecrosis. After debridement, however, either bone or the internal carotid artery is exposed and requires mucosal coverage. OBJECTIVES: This study sought to demonstrate the effectiveness of a nasoseptal flap (NSF) after endoscopic debridement of radionecrosis in the reconstruction of nasopharyngeal or skull base defects...
October 25, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29070165/optimal-cutoff-values-of-allergen-specific-immunoglobulin-e-to-house-dust-mites-and-animal-dander-based-on-skin-prick-test-results-analysis-in-16-209-patients-with-allergic-rhinitis
#2
(no author information available yet)
BACKGROUND: The most common tests for allergen sensitization in patients with allergic rhinitis are the skin-prick test(SPT) and an in vitro test to detect serum specific immunoglobulin E (sIgE). However, in vitro allergen test results were interpreted dichotomically as positive or negative at a threshold of 0.35kU/L of sIgE, regardless of the patient characteristics or antigen types. OBJECTIVE: The purpose of this study was to determine the cutoff value for sIgE in house-dust mites and animal dander, and to analyze differences in cutoff value according to age and gender...
October 25, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28927491/effectiveness-of-intranasal-sodium-hyaluronate-in-mitigating-adverse-effects-of-nasal-continuous-positive-airway-pressure-therapy
#3
(no author information available yet)
BACKGROUND: Nasal continuous positive airway pressure (CPAP) in moderate-to-severe cases of obstructive sleep apnea cancause nasal discomfort and other undesirable problems. OBJECTIVE: The aim of our study was to test the effects of sodium hyaluronate on nasal problems that patients experienced in their daily lives, sleepiness, nasal resistance to airflow, nasal mucociliary clearance, changes in inflammatory markers, and compliance to CPAP in three groups of patients with obstructive sleep apnea syndrome on CPAP therapy...
September 19, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28927489/role-of-exhaled-nasal-nitric-oxide-in-distinguishing-between-chronic-rhinosinusitis-with-and-without-nasal-polyps
#4
(no author information available yet)
BACKGROUND: Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP) nasal polypsis a global health concern. Several clinical biomarkers, such as inhaled carbon monoxide and exhaled nitric oxide (NO), have been studied to assess the presence and degree of inflammation in the airway mucosa. OBJECTIVE: To evaluate the clinical application of exhaled nasal NO (nNO) in distinguishing between CRSwNP and CRSsNP in consideration of the atopic status of patients...
September 19, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29122085/influence-of-chitosan-based-dressing-on-prevention-of-synechia-and-wound-healing-after-endoscopic-sinus-surgery-a-meta-analysis
#5
Jie Liu, Quan Zeng, Xia Ke, Yucheng Yang, Guohua Hu, Xuan Zhang
INTRODUCTION: Endoscopic sinus surgery (ESS) has had many complications, e.g., synechia formation. This meta-analysis investigated the effect of a novel chitosan-based dressing on prevention of synechia and wound healing after ESS. METHODS: We systematically searched various medical literature data bases and included the randomized controlled trials (RCT) regarding the effect of novel chitosan-based dressing on ESS. The study outcomes included synechia, granulations, hemostasis, crusting scores, and infection...
November 4, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29122089/acute-radiology-rarely-confirms-sinus-disease-in-suspected-recurrent-acute-rhinosinusitis
#6
Ronald G Amedee
No abstract text is available yet for this article.
November 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29122088/factors-that-contribute-to-disagreement-in-satisfaction-between-surgeons-and-patients-after-corrective-septorhinoplasty
#7
Jong-Yeup Kim, Min-Ji Cha, Soon-Sung Kwon, Dong-Kyu Kim
BACKGROUND: Corrective septorhinoplasty is one of the most common facial plastic surgeries. However, surgeons and patients sometimes disagree about postoperative-outcome satisfaction after corrective septorhinoplasty. OBJECTIVE: We investigated the factors that influenced the disagreement in satisfaction between surgeons and patients after corrective septorhinoplasty. METHODS: Surgeon satisfaction was assessed by other plastic surgeons by comparing patient photographs taken at the preoperative and 12-month postoperative periods...
November 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29122087/comparison-of-two-concentrations-of-triamcinolone-injection-in-the-prevention-of-supratip-edema-after-external-rhinoplasty-a-randomized-trial
#8
Babak Saedi, Amin Amali, Mina Arabpor
BACKGROUND: A comparison of the two methods of corticosteroid (triamcinolone) use in reducing supratip edema (pollybeak deformity) after rhinoplasty. METHODS: Ninety patients who were candidates for rhinoplasty were randomly divided into three groups. Group A received no treatment, group B received 8 mg/mL of triamcinolone, and group C received 16 mg/mL of triamcinolone. Their effects on dorsal edema were evaluated by using the patients' and surgeons' visual analog scale scores...
November 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29122086/endonasal-endoscopic-management-of-frontal-sinus-cerebrospinal-fluid-leak
#9
Javaneh Jahanshahi, Mehdi Zeinalizadeh, Hasan Reza Mohammadi, Seyed Mousa Sadrehosseini
BACKGROUND: A frontal sinus leak is uncommon and is seen in ∼15% of cases of patients with cerebrospinal fluid (CSF) rhinorrhea. Now, endonasal endoscopic techniques have been reported to reconstruct skull base defects in the frontal sinus with a favorable outcome. OBJECTIVE: To review our experience in the repair of frontal sinus CSF leaks through an endonasal endoscopic approach. METHODS: Twenty-four patients with a frontal sinus leak who underwent endonasal endoscopic repair entered the study...
November 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29122084/vitamin-d%C3%A2-deficiency-and-its-association-with-nasal-polyposis-in-patients-with-cystic-fibrosis-and-patients-with-chronic-rhinosinusitis
#10
Iordanis Konstantinidis, Maria Fotoulaki, Ioannis Iakovou, Angelos Chatziavramidis, Vasilios Mpalaris, Kseniya Shobat, Konstantinos Markou
BACKGROUND: Currently vitamin D3 (VD3) or cholecalciferol is considered an immunomodulator that may be implicated in nasal polyposis (NP) pathophysiology. OBJECTIVES: This study aimed to investigate if deficiency of VD3 is associated with the presence of NP in patients with cystic fibrosis (CF) and patients with chronic rhinosinusitis (CRS). METHODS: In total, 152 adult participants were included in five phenotypic groups: CF with NP (CFwNP) (n = 27), CF without NP (CFsNP) (n = 31), CRS with NP (CRSwNP) (n = 32), CRS without NP (CRSsNP) (n = 30), and controls (n = 32)...
November 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29122083/biocompatibility-and-pharmacokinetics-of-fluticasone-eluting-sinus-implant-in-a-rabbit-model
#11
Vishal S Patel, Evan Walgama, Alkis Psaltis, Francois Lavigne, Steven D Pletcher, Peter H Hwang
BACKGROUND: A novel, bioabsorbable, fibrinogen-based implant has been developed as a mucosal dressing after endoscopic sinus surgery (ESS). This implant can be formulated with fluticasone propionate (FP) for local elution of corticosteroid to reduce postoperative inflammation and promote mucosal healing. OBJECTIVE: This study investigated the biocompatibility and pharmacokinetics of the implant in a rabbit model. METHODS: Implants with and without FP were placed on both intact and demucosalized maxillary sinuses of 33 New Zealand White rabbits...
November 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29122082/the-relationship-between-social-determinants-of-health-and-utilization-of-tertiary-rhinology-care
#12
Madeleine B Samuelson, Rakesh K Chandra, Justin H Turner, Paul T Russell, David O Francis
BACKGROUND: Chronic rhinosinusitis (CRS) has a high prevalence and significant cost and quality of life implications. Many types of practitioners care for patients with rhinosinusitis; however, patients with chronic or complicated conditions are often referred for tertiary rhinology services. It is unclear how social determinants of health affect access and utilization of these services. A better understanding of social barriers to tertiary rhinology care is needed to reduce health care disparities and improve health outcomes...
November 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29122081/gender-specific-differences-in-serum-immunoglobulin-e-levels-and-prevalence-of-fungus-in-sinonasal-tissue-noted-in-patients-with-chronic-rhinosinusitis-who-underwent-endoscopic-sinus-surgery
#13
Antoine Azar, Matthew A Rank, Matthew A Zarka, Yu-Hui Chang, Devyani Lal
BACKGROUND: We previously presented that women with chronic rhinosinusitis (CRS) who elected endoscopic sinus surgery (ESS) have a higher symptom burden than men. Causes of these gender-based differences warranted further study. OBJECTIVES: To study gender differences in another cohort of adult patients with CRS who underwent ESS and to compare key histopathologic and serologic features Methods: Patients with CRS who underwent ESS (from 2011 to 2014) with structured histopathology reports on surgical samples were studied...
November 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29122080/role-of-adenosine-monophosphate-activated-protein-kinase-on-cell-migration-matrix-contraction-and-matrix-metalloproteinase-1-and-matrix-metalloproteinase-2-production-in-nasal-polyp-derived-fibroblasts
#14
Ji-Young Um, Seoung-Ae Lee, Joo-Hoo Park, Jae-Min Shin, Il-Ho Park, Heung-Man Lee
PURPOSE: Activation of adenosine monophosphate-activated protein kinase (AMPK) by metformin, as a master regulator of metabolism, is involved in airway tissue remodeling. Here, we investigated the physical role of AMPK on cell migration, matrix contraction, and the production of matrix metalloproteinases (MMP) in nasal polyp-derived fibroblasts (NPDF). METHODS: Primary NPDFs from six patients with chronic rhinosinusitis and nasal polyps were isolated and cultured...
November 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29122079/sinonasal-t-cell-expression-of-cytotoxic-mediators-granzyme-b-and-perforin-is-reduced-in-patients-with-chronic-rhinosinusitis
#15
Sarah E Smith, Rodney J Schlosser, James R Yawn, Jose L Mattos, Zachary M Soler, Jennifer K Mulligan
BACKGROUND: CD8+ T cells and natural killer (NK) cells are cytotoxic cells that use granzyme B (GrB) and perforin. Defective cytotoxic function is known to play a role in dysregulated immune response as seen in chronic sinusitis, also referred to as chronic rhinosinusitis (CRS). However, to our knowledge, in the United States, neither GrB or perforin expression has been reported in patients with CRS. OBJECTIVE: The aim of this study was to investigate sinonasal cytotoxic cells, their mediators, and cell-specific distribution of these mediators in patients with CRS with nasal polyp (CRSwNP) and in patients with CRS without nasal polyp (CRSsNP)...
November 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29122078/the-role-of-regulatory-t-cells-in-the-regulation-of-upper-airway-inflammation
#16
Charlie Palmer, Jennifer K Mulligan, Sarah E Smith, Carl Atkinson
Allergic rhinitis (AR) and chronic rhinosinusitis with nasal polyps (CRSwNP) are inflammatory diseases of the upper airway, with a similar immunologic profile, characterized by aberrant and persistent type 2 inflammation. One cell population that has been identified as altered in both disease types is regulatory T cell (Treg). Tregs have the capacity to modulate T-effector function and suppress inflammatory cytokine production in a broad range of cell types. Given the ability of Tregs to control inflammation, the role of Tregs in respiratory diseases has attracted much attention...
November 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29122077/beyond-borders-and-sinuses-rhinology-and-allergy-research-on-a-world-stage
#17
Alkis James Psaltis
No abstract text is available yet for this article.
November 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29122076/a-systematic-review-of-secondary-cerebrospinal-fluid-leaks
#18
Neeraja Konuthula, Mohemmed N Khan, Anthony Del Signore, Satish Govindaraj, Raj Shrivastava, Alfred M Iloreta
BACKGROUND: Secondary cerebrospinal leaks (CSF) are leaks that recur after an initial endoscopic repair of CSF leaks. Identification of characteristics that could predict secondary leaks may allow surgeons to plan repairs with the knowledge that these defects are more likely to fail. OBJECTIVE: To identify characteristics that could predict secondary CSF leaks. METHODS: A search of all studies that reported outcomes after endoscopic repair of CSF leaks was conducted by using medical literature data bases...
November 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28859714/utility-of-intraoperative-frozen-sections-in-surgical-decision-making-for-acute-invasive-fungal-rhinosinusitis
#19
Ronald G Amedee
No abstract text is available yet for this article.
September 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28859713/draf-iii-frontal-sinus-surgery-how-i-do-it
#20
A Simon Carney
BACKGROUND: The Draf III approach to the frontal sinus can be used during revision endoscopic sinus surgery for chronic rhinosinusitis and to provide access for tumor resection, mucoceles, and repair of cerebrospinal fluid leaks. OBJECTIVE: To describe a simple and safe way to perform a Draf III approach by using the "outside-in" approach. METHODS: By using a 0° endoscope and a single 15°, 5-mm, coarse diamond burr, the main steps of the procedure are the following: (1) elevation of the mucosal flaps and creation of the septal window, (2) drilling out the frontal beak, (3) creation of neo-ostium and removal of the interfrontal septum, (4) joining the neo-ostium with the frontal recesses, (5) smoothing off the cavity and lowering of the "frontal T," and (6) use of mucosal flaps and grafts to cover exposed bone...
September 1, 2017: American Journal of Rhinology & Allergy
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