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American Journal of Rhinology & Allergy

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https://www.readbyqxmd.com/read/29649882/local-atopy-in-childhood-adenotonsillar-hypertrophy
#1
Kyu-Sup Cho, Seong Heon Kim, Sung-Lyong Hong, Jaeyoung Lee, Sue Jean Mun, Young Eun Roh, Young Mi Kim, Hye-Young Kim
Background Although the cause of adenotonsillar hypertrophy remains unknown, some studies have shown that allergy may be a risk factor. Purpose This study determined the levels of allergen-specific immunoglobulin E (sIgE) in the adenotonsillar tissues of children with adenotonsillar hypertrophy and evaluated the clinical significance of local atopy in adenotonsillar tissues. Methods We measured 21 types of specific immunoglobulin E in the serum and adenotonsillar tissues of 102 children with adenotonsillar hypertrophy and compared the sensitization patterns of the serum and local tissues...
May 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29644907/remodeling-of-the-paradoxical-middle-turbinate-preserving-function-while-gaining-access
#2
Ryan H Belcher, Allison K Ikeda, John M DelGaudio
Background Endoscopic sinus surgery is performed for many reasons, most commonly for chronic rhinosinusitis refractory to medical treatment. A paradoxical middle turbinate is an anatomic variant that can hinder endoscopic access to the sinuses. No publication has addressed how to surgically treat a paradoxical middle turbinate. Method We present a basic endoscopic surgical approach to conservatively resect a paradoxical middle turbinate in order to improve access to the middle meatus and the sinuses while preserving support and function...
March 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29644906/does-heating-up-saline-for-nasal-irrigation-improve-mucociliary-function-in-chronic-rhinosinusitis
#3
Suthanma Nimsakul, Saran Ruxrungtham, Supinda Chusakul, Jesada Kanjanaumporn, Songklot Aeumjaturapat, Kornkiat Snidvongs
Background Mucociliary function is affected by temperature. Exposure to cold air may impair ciliary beat frequency. While saline nasal irrigation improves in ciliary beat activity, there is no evidence supporting the use of heated saline irrigation in treating patients with chronic rhinosinusitis. Objective To compare the effects of heated saline to room-temperature saline nasal irrigation on mucociliary clearance in chronic rhinosinusitis patients. Methods Adult patients with chronic rhinosinusitis were randomized into two groups receiving either heated saline or room-temperature saline nasal irrigation...
March 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29644905/histopathology-in-chronic-rhinosinusitis-varies-with-sinus-culture
#4
Ashley L Heilingoetter, Bobby Tajudeen, Hannah N Kuhar, Paolo Gattuso, Ritu Ghai, Mahboobeh Mahdavinia, Pete S Batra
Background Structured histopathology reporting facilitates better understanding of the underlying pathophysiologic mechanisms of chronic rhinosinusitis. The microbiology of chronic rhinosinusitis has been studied extensively; however, distinct histopathologic changes associated with bacteria isolated in chronic rhinosinusitis are largely unknown. Objective The goal of this study is to better understand the relationship between culturable bacteria and histopathology in chronic rhinosinusitis. Methods A structured histopathology report was utilized to analyze sinus tissue removed during functional endoscopic sinus surgery in a group of patients with chronic rhinosinusitis refractory to medical therapy...
March 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29644904/survivin-and-cortactin-expression-in-sinonasal-schneiderian-inverted-papilloma-and-associated-carcinoma
#5
Gino Marioni, Giuseppe Brescia, Lorenzo Nicolè, Rosario Marchese-Ragona, Umberto Barion, Luciano Giacomelli, Filippo Marino, Alessandro Martini, Giancarlo Ottaviano
BACKGROUND: Sinonasal inverted (schneiderian) papilloma (IP) is histologically benign but shows a propensity for malignant transformation. Survivin, a member of the inhibitor of the apoptosis family of proteins that controls cell division, apoptosis, metastasis, and, probably, also neoangiogenesis, is overexpressed in essentially all human cancers. Overexpression of the multidomain protein cortactin has also been associated with increased cell migration, invasion, and metastatic potential in several malignancies...
March 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29644903/patients-with-chronic-rhinosinusitis-and-obstructive-sleep-apnea-have-increased-paroxysmal-limb-movement
#6
Mahboobeh Mahdavinia, Jessica W Hui, Mohamed Zitun, Alejandra Lastra, James J Herdegen, Christopher D Codispoti, Rafsa J Khan, Phillip S LoSavio, Pete S Batra
BACKGROUND: Patients with chronic rhinosinusitis (CRS) frequently experience sleep disruption and are at a higher than normal risk for obstructive sleep apnea (OSA). The purpose of this study was to determine how CRS affects polysomnography findings and sleep-related breathing in OSA. METHODS: A cohort study was performed that included 107 adult patients with CRS and comorbid OSA (CRS+OSA group) and 137 patients with OSA and without CRS as the control group. An electronic medical records database was used to identify eligible subjects...
March 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29644902/interleukin-il-36-gamma-induces-mucin-5ac-oligomeric-mucus-gel-forming-expression-via-il-36-receptor-extracellular-signal-regulated-kinase-1-and-2-and-p38-nuclear-factor-kappa-light-chain-enhancer-of-activated-b-cells-in-human-airway-epithelial-cells
#7
Chang Hoon Bae, Yoon Seok Choi, Hyung Gyun Na, Si-Youn Song, Yong-Dae Kim
BACKGROUND: Mucin 5AC, oligomeric mucus/gel-forming (MUC5AC) expression is significantly increased in allergic and inflammatory airway diseases. Interleukin (IL) 36 gamma is predominantly expressed in airway epithelial cells and plays an important role in innate and adaptive immune responses. IL-36 gamma is induced by many inflammatory mediators, including cytokines and bacterial and viral infections. However, the association between IL-36 gamma and mucin secretion in human airway epithelial cells has not yet been fully investigated...
March 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29644901/eccentric-mature-osseous-cap-a-distinct-imaging-feature-of-sinonasal-osteoblastoma
#8
Sumeet G Dua, Philip H Locker, Isolina R Rossi, Danny Jandali, Paulo Gattuso, Pete S Batra, Bobby A Tajudeen
BACKGROUND: With the exception of osteomas, bone neoplasms that originate in the sinonasal cavity are seldom diagnosed on preoperative imaging due to a lack of characteristic radiographic features. Here we described the unusual occurrence of an osteoblastoma in the paranasal sinuses, and we drew focus to its salient imaging features. A highly unique imaging sign was indicated, and its pathologic basis was explained, with concurrent review of the literature. METHODS: Case series and review of the literature...
March 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29644900/discordance-in-preoperative-and-postoperative-histopathology-of-sinonasal-tumors
#9
Ashwin Ganti, Bobby A Tajudeen, Max A Plitt, Isolina Rossi, Paolo Gattuso, Pete S Batra
Background Head and neck surgical pathology has been shown to be prone to histopathologic diagnostic error that can adversely impact patient care due to inappropriate management. Sinonasal tumors, in particular, present a diagnostic challenge given the relative rarity and diversity in histology and thus may have higher rates of discordant histology. Objective The purpose of this study is to determine the rate of discrepancy between preoperative and postoperative diagnoses of sinonasal tumors. Methods Retrospective chart review was performed on 52 patients treated for sinonasal tumors between January 2013 and December 2016...
March 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29644899/technical-notes-on-the-endoscopic-endonasal-approach-to-the-craniovertebral-junction-for-odontoidectomy
#10
Dennis Tang, Christopher Roxbury, Brian D'Anza, Varun Kshettry, Troy Woodard, Pablo Recinos, Raj Sindwani
INTRODUCTION: Odontoidectomy can help decompress ventral compression of the brainstem and upper cervical spinal cord in the presence of bony abnormalities of the craniovertebral junction (CVJ), e.g., an odontoid pannus. Endonasal approaches have been shown to be associated with lower morbidity compared with traditional transoral approaches. We demonstrated an entirely endonasal approach to the CVJ. MATERIALS AND METHODS: We presented our technique for performing an endoscopic endonasal odontoidectomy...
March 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29644898/a-new-chapter-for-the-american-journal-of-rhinology-and-allergy
#11
Rakesh K Chandra, Anju T Peters, Raj Sindwani
No abstract text is available yet for this article.
March 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29336293/using-the-nasoseptal-flap-for-reconstruction-after-endoscopic-debridement-of-radionecrosis-in-nasopharyngeal-carcinoma
#12
Gwanghui Ryu, Yoon Kyoung So, Min Young Seo, Woori Park, Hyo Yeol Kim, Hun-Jong Dhong, Seung-Kyu Chung, Sang Duk Hong
BACKGROUND: Radionecrosis is a complication of nasopharyngeal carcinoma (NPC) that is difficult to treat. Endoscopic debridement is the first-line treatment for radionecrosis. After debridement, however, either bone or the internal carotid artery is exposed and requires mucosal coverage. OBJECTIVES: This study sought to demonstrate the effectiveness of a nasoseptal flap (NSF) after endoscopic debridement of radionecrosis in the reconstruction of nasopharyngeal or skull base defects...
January 25, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29336285/optimal-cutoff-values-of-allergen-specific-immunoglobulin-e-to-house-dust-mites-and-animal-dander-based-on-skin-prick-test-results-analysis-in-16-209-patients-with-allergic-rhinitis
#13
Sang Duk Hong, Gwanghui Ryu, Min Young Seo, Jong In Jeong, Hyo Yeol Kim, Seung-Kyu Chung, Hun-Jong Dhong
BACKGROUND: The most common tests for allergen sensitization in patients with allergic rhinitis are the skin-prick test (SPT) and an in vitro test to detect serum specific immunoglobulin E (sIgE). However, in vitro allergen test results were interpreted dichotomically as positive or negative at a threshold of 0.35 kU/L of sIgE, regardless of the patient characteristics or antigen types. OBJECTIVE: The purpose of this study was to determine the cutoff value for sIgE in house-dust mites and animal dander, and to analyze differences in cutoff value according to age and gender...
January 25, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29774747/hypertonic-saline-versus-isotonic-saline-nasal-irrigation-systematic-review-and-meta-analysis
#14
Dichapong Kanjanawasee, Kachorn Seresirikachorn, Wirach Chitsuthipakorn, Kornkiat Snidvongs
Background Saline nasal lavage is one of the treatments of sinonasal diseases. Evidence from basic research favors hypertonic saline (HS) over isotonic saline (IS) for mucociliary clearance, but evidence from clinical studies is controversial. Conversely, HS may carry greater side effects. Objective To compare the effects of HS and IS nasal irrigation in treating sinonasal diseases. Methods Systematic search with Ovid MEDLINE, Scopus, PubMed, Google Scholar, and Manual additional sources was conducted. Randomized controlled trials comparing HS with IS nasal irrigation in treating any sinonasal diseases, including rhinitis and rhinosinusitis, were included...
January 1, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29754498/axonal-guidance-signaling-pathway-is-suppressed-in-human-nasal-polyps
#15
Dawei Wu, Sarina K Mueller, Angela L Nocera, Kristen Finn, Towia A Libermann, Benjamin S Bleier
Background Dysfunctional innervation might contribute to the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP), but the state of the axonal outgrowth signaling in CRSwNP is unknown. The purpose of this study was to explore the axonal outgrowth pathway-related protein expression in CRSwNP. Methods Institutional review board approved study in which tissue proteomes were compared between control and CRSwNP patients (n = 10/group) using an aptamer-based proteomic array and confirmed by whole transcriptomic analysis...
January 1, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29745245/endoscopic-powered-dacryocystorhinostomy-without-stenting-long-term-outcomes-of-120-procedures
#16
Ejder Ciğer, Mustafa K Balci, Seçil Arslanoğlu, Erdem Eren
Background The necessity of silicone stenting in endoscopic dacryocystorhinostomy (DCR) procedures is a controversial subject in the literature. Objective The purpose of the present study is to assess the long-term anatomical and functional outcomes of endoscopic-powered DCR (EP-DCR) without stenting or mucosal flaps. Methods One hundred twenty EP-DCR procedures were performed in 107 patients. Anatomical success was defined as a patent ostium on irrigation and functional success as free flow of dye from the ostium and resolution of epiphora...
January 1, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29745243/bevacizumab-for-epistaxis-in-hereditary-hemorrhagic-telangiectasia-an-evidence-based-review
#17
Ashleigh A Halderman, Matthew W Ryan, Bradley F Marple, Raj Sindwani, Douglas D Reh, David M Poetker
Objective Epistaxis is a primary complaint in 90% to 96% of patients with hereditary hemorrhagic telangiectasia (HHT). Numerous surgical and medical treatments aim to decrease the frequency and severity of epistaxis in this patient population. Bevacizumab is a recombinant, humanized monoclonal antibody to vascular endothelial growth factor, an angiogenic factor elevated in HHT. It has been used in several forms to treat epistaxis in HHT but thus far, evidence-based recommendations are limited. Study Design Systematic review with evidence-based recommendations...
January 1, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29741096/clinical-predictors-of-frontal-ostium-restenosis-after-draf-3-procedure-for-refractory-chronic-rhinosinusitis
#18
Xiaoqing Zhang, Ting Ye, Zhenxiao Huang, Qian Huang, Junfang Xian, Jing Li, Bing Zhou
Background The Draf 3 procedure has been demonstrated to be effective in the treatment of refractory frontal sinus disease. A variety of clinical factors may contribute to the change of frontal neo-ostium (FNO) area after this procedure. Imaging plays a vital role in the evaluation and follow-up after surgery and provides useful prognostic information. Objectives (1) To investigate the influence of local anatomic factors on FNO after a Draf 3 procedure by radiological measurements on imaging software and (2) to explore other predictive factors of FNO restenosis...
January 1, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29732935/use-of-autologous-fat-grafts-for-the-endoscopic-reconstruction-of-skull-base-defects-indications-outcomes-and-complications
#19
Kent Lam, Amber U Luong, William C Yao, Martin J Citardi
Background The use of abdominal free fat is a traditional surgical method for the repair and reconstruction of the anterior skull base. Our objective is to assess the outcomes associated with the autologous fat graft to endoscopically repair anterior skull base defects at a single tertiary care center. Methods All patients, who underwent endoscopic skull base repair utilizing abdominal free fat from September 2009 to June 2016, were included for retrospective chart review. Evaluated outcome measurements included (1) the successful closure of preoperative and intraoperative cerebrospinal fluid (CSF) leaks and (2) complications at both donor and recipient graft sites during the postoperative periods...
January 1, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29732927/nasal-endoscopy-billing-patterns-a-survey-of-the-american-rhinologic-society
#20
Abtin Tabaee, Charles A Riley, Seth M Brown, Edward D McCoul
Introduction Nasal endoscopy (NE) is an essential element of office-based clinical rhinology, including the evaluation of chronic rhinosinusitis. Despite the presence of guidelines, variability exists regarding coding and billing for NE especially with regard to inclusion of evaluation and management (E&M) codes and use of the 25 modifier. The goal of this survey was to assess the billing patterns for NE among American Rhinologic Society (ARS) members. Methods An invitation to participate in a web-based survey was electronically sent to all ARS members...
January 1, 2018: American Journal of Rhinology & Allergy
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