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Diabetology & Metabolic Syndrome

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https://www.readbyqxmd.com/read/29026444/association-of-meal-frequency-with-metabolic-syndrome-in-korean-adults-from-the-korea-national-health-and-nutrition-examination-survey-knhanes
#1
Chan-Hee Jung, Ji Sung Lee, Hee Jung Ahn, Jin-Sun Choi, Min Young Noh, Ji Jeung Lee, Eun Young Lee, Jeong Hyun Lim, Young Ran Lee, So Yoon Yoon, Chong Hwa Kim, Dong-Hyeok Cho, Young Sik Choi, Kyung Mook Choi
BACKGROUND: Although previous studies have established a close relationship between caloric intake and metabolic syndrome, there is limited research exploring the impact of meal frequency adjusted by caloric intake on metabolic syndrome (MetS). OBJECTIVE: To evaluate the association of meal frequency and MetS after adjusting for confounding factors including caloric intake in Korean men and women. METHODS: We analyzed the national representative data of a total 12,389 adults (5171 men, 7218 women) from the Korean National Health and Nutrition Examination Survey (KNHANES) 2010-2012...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/29026443/neutrophil-killing-of-staphylococcus-aureus-in-diabetes-obesity-and-metabolic-syndrome-a-prospective-cellular-surveillance-study
#2
Ingrid Lea Scully, Lisa Kristin McNeil, Sudam Pathirana, Christine Lee Singer, Yongdong Liu, Stanley Mullen, Douglas Girgenti, Alejandra Gurtman, Michael W Pride, Kathrin Ute Jansen, Paul L Huang, Annaliesa S Anderson
BACKGROUND: Obesity, metabolic syndrome (MetS), and diabetes are frequent in surgical populations and can enhance susceptibility to postoperative surgical site infections. Reduced neutrophil function has been linked with diabetes and risk of Staphylococcus aureus infection. Therefore, neutrophil function in diabetic and obese subjects (± MetS) was assessed in this prospective serological and cellular surveillance study to determine whether vaccines administered to protect against infections after surgery could be effective in these populations...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/29021829/review-article-effects-of-type-2-diabetes-therapies-on-bone-metabolism
#3
REVIEW
A G D Vianna, C P Sanches, F C Barreto
Diabetes complications and osteoporotic fractures are two of the most important causes of morbidity and mortality in older patients, and they share many features, including genetic susceptibility, molecular mechanisms, and environmental factors. Type 2 diabetes mellitus (T2DM) compromises bone microarchitecture by inducing abnormal bone cell function and matrix structure with increased osteoblast apoptosis, diminished osteoblast differentiation, and enhanced osteoclast-mediated bone resorption. The linkage between these two chronic diseases creates a possibility that certain antidiabetic therapies may affect bone function...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/29021828/endurance-exercise-training-decreased-serum-levels-of-surfactant-protein-d-and-improved-aerobic-fitness-of-obese-women-with-type-2-diabetes
#4
Sajjad Rezaei, Mahdieh Molanouri Shamsi, Mehdi Mahdavi, Azadeh Jamali, Jonato Prestes, Ramires Alsamir Tibana, James Wilfred Navalta, Fabrício Azevedo Voltarelli
BACKGROUND: Surfactant protein D (SP-D) is a member of the collectin family and is an important component of the pulmonary innate host defense. To find the relationship between exercise training and SP-D in diabetes, we examined the possible effects of a 10-week endurance exercise-training program on serum levels of SP-D, leptin, lipid profile and insulin resistance in obese women with type-2 diabetes mellitus (T2DM). METHODS: Twenty-two obese women with T2DM were randomly assigned to either exercise training (ET) or control (C) group...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/29018490/the-promotion-of-nephropathy-by-porphyromonas-gingivalis-lipopolysaccharide-via-toll-like-receptors
#5
Koichiro Kajiwara, Shunsuke Takata, Thao T To, Kenyo Takara, Yuji Hatakeyama, Sachio Tamaoki, Richard Peters Darveau, Hiroyuki Ishikawa, Yoshihiko Sawa
BACKGROUND: Recently, we reported that toll-like receptor (TLR)2 and TLR4 localized on the glomerular endothelium in the glomeruli of streptozotocin (STZ)-induced type 1 diabetic mice and high fat diet feed-induced type 2 diabetic mice, and that periodontal pathogen Porphyromonas gingivalis LPS (Pg-LPS) administration lowered the survival rate of diabetic mice. The present study aims to examine the effect of TLR4 blocking on the suppression of Pg-LPS-induced diabetic nephropathy. METHODS: The survival rate and morphological/biochemical features for streptozotocin-induced diabetic mice with Pg-LPS and TLR4 blocker eritoran administration were investigated by reporter gene assay, urine and blood analysis, immunohistochemistry, and real time-PCR...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28943894/prevalence-and-severity-of-syndrome-z-in-women-with-metabolic-syndrome-on-waiting-list-for-bariatric-surgery-a-cross-sectional-study
#6
Eduardo Araujo Perez, Luis Vicente Franco Oliveira, Wilson Rodrigues Freitas, Carlos Alberto Malheiros, Elias Jirjoss Ilias, Anderson Soares Silva, Jessica Julioti Urbano, Patricia Clemente Oliveira, Felipe X Cepeda, Luciana M M Sampaio, Ivani C Trombetta, Humberto Delle, Daniel Gianella Neto, Sergio Roberto Nacif, Roberto Stirbulov
BACKGROUND: In recent years, obesity has become one of the most important public health problems in the world, with a growing prevalence in both developed and developing countries. Recent studies show that sleep disturbances, especially obstructive sleep apnoea (OSA) may be a manifestation of metabolic syndrome (MetS). Although the association of OSA with the MetS is largely attributed to obesity, the exact pathophysiological mechanisms and their individual characteristics still need to be identified...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28932290/moderate-to-high-intensity-statins-for-secondary-prevention-in-patients-with-type-2-diabetes-mellitus-on-dialysis-after-acute-myocardial-infarction
#7
Yan-Rong Li, Sung-Sheng Tsai, Yu-Sheng Lin, Chang-Min Chung, Szu-Tah Chen, Jui-Hung Sun, Miaw-Jene Liou, Tien-Hsing Chen
BACKGROUND: Evidences support the benefits of moderate- to high-intensity statins for patients with acute myocardial infarction (AMI) except for those with type 2 diabetes mellitus (T2DM) on dialysis after AMI. This study was aimed to investigate the safety and efficacy of secondary prevention of cardiovascular diseases using moderate- to high-intensity statins in T2DM patients on dialysis after AMI. METHODS: A simulated prospective cohort study was conducted between January 1st, 2001 and December 31st, 2013 utilizing data from the Taiwan National Health Insurance Research Database...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28932289/erratum-to-cardiovascular-risk-assessment-in-patients-with-diabetes
#8
Marcello Casaccia Bertoluci, Viviane Zorzanelli Rocha
[This corrects the article DOI: 10.1186/s13098-017-0225-1.].
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28912840/the-relationship-between-insulin-sensitivity-and-heart-rate-corrected-qt-interval-in-patients-with-type-2-diabetes
#9
Xiao-Hua Yang, Jian-Bin Su, Xiu-Lin Zhang, Li-Hua Zhao, Feng Xu, Xue-Qin Wang, Xing-Bo Cheng
BACKGROUND: Reduced insulin sensitivity not only contributes to the pathogenesis of type 2 diabetes but is also linked to multiple metabolic risk factors and cardiovascular diseases (CVD). A prolonged heart rate-corrected QT interval (QTc interval) is related to ventricular arrhythmias and CVD mortality and exhibits a high prevalence among type 2 diabetes patients. The aim of the study was to investigate the relationship between insulin sensitivity and the QTc interval in patients with type 2 diabetes...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28912839/addition-of-nonalbumin-proteinuria-to-albuminuria-improves-prediction-of-type-2-diabetic-nephropathy-progression
#10
Jong Ho Kim, Seo Young Oh, Eun Heui Kim, Min Jin Lee, Yun Kyung Jeon, Bo Hyun Kim, Jin Mi Kim, Yong Ki Kim, Sang Soo Kim, In Joo Kim
BACKGROUND: Albuminuria is generally accepted as a sensitive marker of diabetic nephropathy but has limitations in predicting its progression. The aim of this study was to evaluate the use of nonalbumin proteinuria in addition to albuminuria for predicting the progression of type 2 diabetic nephropathy. METHODS: In this retrospective observational study, the urine albumin-to-creatinine ratio (ACR) and the nonalbumin protein-to-creatinine ratio (NAPCR) were measured in 325 patients with type 2 diabetes and estimated glomerular filtration rates (eGFR) ≥30 mL/min/1...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28883892/impact-of-post-meal-and-one-time-daily-exercise-in-patient-with-type-2-diabetes-mellitus-a-randomized-crossover-study
#11
Daizy Pahra, Nitasha Sharma, Sandhya Ghai, Abhishek Hajela, Shobhit Bhansali, Anil Bhansali
BACKGROUND: To evaluate the effectiveness of short-timed post-meal and one-time daily exercise on glycemic control in patients with T2DM. METHODS: Sixty-four T2DM patients were randomised into crossover design. Group A (n = 32) underwent post-meal exercise (moderate-intensity brisk walking covering 1500-1600 steps for 15 min, starting 15 min after each meal) from d1 to d60 followed by one-time daily exercise (45 min pre-breakfast brisk walking at stretch covering 4500-4800 steps) from d61 to d120, while it was vice versa for the group B (n = 32)...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28878828/elevated-serum-interleukin-6-is-predictive-of-coronary-artery-disease-in-intermediate-risk-overweight-patients-referred-for-coronary-angiography
#12
Marco V Wainstein, Márcio Mossmann, Gustavo N Araujo, Sandro C Gonçalves, Gabriela L Gravina, Marlei Sangalli, Francine Veadrigo, Roselene Matte, Rejane Reich, Fernanda G Costa, Michael Andrades, Antônio Marcos V da Silva, Marcello C Bertoluci
BACKGROUND: Interleukin-6 (IL-6) plays a central role in atherosclerosis and inflammation. It may improve risk prediction in patients at intermediate cardiovascular risk. OBJECTIVE: To analyze the impact of serum IL-6 in predicting early angiographic coronary artery disease in patients at intermediate cardiovascular risk with chest pain. METHODS: In a cross-sectional study, patients referred for coronary angiography due to suspected coronary artery disease (CAD) were included...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28878827/association-of-the-leptin-to-adiponectin-ratio-with-metabolic-syndrome-in-a-sub-saharan-african-population
#13
Clarisse Noël A Ayina, Francky Teddy A Endomba, Samuel Honoré Mandengue, Jean Jacques N Noubiap, Laurent Serge Etoundi Ngoa, Philippe Boudou, Jean-François Gautier, Jean Claude Mbanya, Eugene Sobngwi
BACKGROUND: Worldwide there is an increased prevalence of metabolic syndrome mainly due to life-style modifications, and Africans are not saved of this situation. Many markers have been studied to predict the risk of this syndrome but the most used are leptin and adiponectin. Data on these metabolic markers are scare in Africa and this study aimed to assess the association between the leptin-to-adiponectin ratio (LAR) with metabolic syndrome in a Cameroonian population. METHODS: This was a cross-sectional study that included 476 adults among a general population of Cameroon...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28878826/analysis-of-factors-influencing-glucose-tolerance-in-japanese-patients-with-non-alcoholic-fatty-liver-disease
#14
Satoko Ohmi, Masafumi Ono, Hiroshi Takata, Seiki Hirano, Shogo Funakoshi, Yuichi Nishi, Kumiko Yoshimura, Eri Amano, Yoshio Terada, Toshiji Saibara, Shimpei Fujimoto
BACKGROUND: While the association of the prevalence of non-alcoholic fatty liver disease (NAFLD) with impaired glucose metabolism has been reported, the factors influencing glucose tolerance in NAFLD remain to be clarified. METHODS: Glucose tolerance of 131 Japanese patients diagnosed as NAFLD by histological findings of liver biopsy specimen was examined using 75 g-OGTT. According to Matteoni's classification, patients were divided to 4 groups [M1 ~ 4, M1, 2: non-alcoholic fatty liver (NAFL); and M3, 4: non-alcoholic steatohepatitis (NASH)]...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28828040/association-between-aerobic-capacity-and-the-improvement-in-glycemic-control-after-the-exercise-training-in-type-2-diabetes
#15
Hideki Nojima, Masayasu Yoneda, Hiroshi Watanabe, Kiminori Yamane, Yoshihiro Kitahara, Kiyokazu Sekikawa, Hideya Yamamoto, Akihito Yokoyama, Noboru Hattori, Nobuoki Kohno
BACKGROUND: We investigated the influence of aerobic capacity on the improvement in glycemic control achieved by long-term aerobic exercise in type 2 diabetes. METHODS: Fifty-three male patients with type 2 diabetes, recruited from outpatient clinics, wore multiple-memory accelerometers and were instructed to exercise at moderate intensity for ≥30 min on ≥3 days per week over 12 months. Peak oxygen uptake (peak [Formula: see text]) and serum glycated albumin (GA) were measured at baseline and after 3, 6, 12 months...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28814977/worse-inflammatory-profile-in-omnivores-than-in-vegetarians-associates-with-the-gut-microbiota-composition
#16
Ana Carolina Franco-de-Moraes, Bianca de Almeida-Pititto, Gabriel da Rocha Fernandes, Everton Padilha Gomes, Alexandre da Costa Pereira, Sandra Roberta G Ferreira
AIMS: To describe the abundance of major phyla and some genera in the gut microbiota of individuals according to dietary habits and examine their associations with inflammatory markers, insulin resistance, and cardiovascular risk profile. METHODS: A total of 268 non-diabetic individuals were stratified into groups of dietary types (strict vegetarians, lacto-ovo-vegetarians, and omnivores). The taxonomic composition and phylogenetic structure of the microbiota were obtained through the analysis of the 16S rRNA gene...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28794803/translation-and-cultural-adaptation-into-brazilian-culture-of-type-1-diabetes-distress-scale
#17
M S V M Silveira, T G Bovi, P F Oliveira, E J Pavin, L Fisher
BACKGROUND: Diabetes related distress is common in type 1 diabetes patients (T1D). High levels of diabetes distress are related to poor metabolic control. An instrument to evaluate diabetes distress in T1D patients is "type 1 diabetes scale-T1DDS". The aim of this study was to translate and culturally adapt the T1DDS into Brazilian culture. METHODS: T1DDS scale was translated into Portuguese. Back translation was performed and evaluated by a specialists committee...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28785316/early-effects-of-sodium-glucose-co-transporter-2-inhibitors-in-type-2-diabetes-study-based-on-continuous-glucose-monitoring
#18
Keiichi Torimoto, Yosuke Okada, Kenji Koikawa, Yoshiya Tanaka
BACKGROUND: Inhibitors of sodium-glucose co-transporter 2 (SGLT2) have immediate glucose-lowering effects by promoting urinary glucose excretion, without altering insulin level. Only a few studies have evaluated blood glucose dynamics in the early period after administration. The present retrospective study was designed to determine the immediate effects of SGLT2 inhibitors on blood glucose dynamics. METHODS: The study subjects were 24 patients with type 2 diabetes whose blood glucose dynamics were evaluated with continuous glucose monitoring for 1 week before and after initiation of SGLT2 inhibitor therapy...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28770011/interactions-between-antidiabetic-drugs-and-herbs-an-overview-of-mechanisms-of-action-and-clinical-implications
#19
REVIEW
Ramesh C Gupta, Dennis Chang, Srinivas Nammi, Alan Bensoussan, Kellie Bilinski, Basil D Roufogalis
Diabetes is a complex condition with a variety of causes and pathophysiologies. The current single target approach has not provided ideal clinical outcomes for the treatment of the disease and its complications. Herbal medicine has been used for the management of various diseases such as diabetes over centuries. Many diabetic patients are known to use herbal medicines with antidiabetic properties in addition to their mainstream treatments, which may present both a benefit as well as potential risk to effective management of their disease...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28770010/a-qualitative-study-to-explore-the-perception-and-behavior-of-patients-towards-diabetes-management-with-physical-disability
#20
Syed Wasif Gillani, Syed Azhar Syed Sulaiman, Mohi Iqbal Mohammad Abdul, Sherif Y Saad
BACKGROUND: This study aimed to determine self-monitoring practices, awareness to dietary modifications and barriers to medication adherence among physically disabled type 2 diabetes mellitus patients. METHODS: Interview sessions were conducted at diabetes clinic-Penang general hospital. The invited participants represented three major ethnic groups of Malaysia (Malay, Chinese and Indians). An open-ended approach was used to elicit answers from participants. Interview questions were related to participant's perception towards self-monitoring blood glucose practices, Awareness towards diet management, behaviour to diabetes medication and cues of action...
2017: Diabetology & Metabolic Syndrome
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