Ting Gong, Yujing Zhou, Qinhong Shi, Yanyan Li, Haizhu Wang, Min Zhang, Linzheng Liao
Extensive research has been conducted to investigate the impact of capsaicin (CAP) on lipid metabolism, focusing specifically on its interaction with the vanilloid subtype 1 (TRPV1) ion channel. Additionally, studies have illuminated the role of Akkermansia muciniphila ( A. muciniphila ), a specific strain of intestinal microbiota, in lipid metabolism. In this study, a model utilizing resiniferatoxin (RTX) was employed to deactivate TRPV1 ion channels in germ-free mice, followed by the administration of A. muciniphila via gavage...
2023: Food & Nutrition Research