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Food & Nutrition Research

Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Shaheen Majeed, Furqan Ali
Background: The modification of microbial ecology in human gut by supplementing probiotics may be an alternative strategy to ameliorate or prevent depression. Objective: The current study was conducted to assess the safety and efficacy of the probiotic strain Bacillus coagulans MTCC 5856 for major depressive disorder (MDD) in IBS patients. Method: Patients ( n = 40) diagnosed for MDD with IBS were randomized (1:1) to receive placebo or B. coagulans MTCC 5856 at a daily dose of 2 × 109 cfu (2 billion spores) and were maintained to the end of double-blind treatment (90 days)...
2018: Food & Nutrition Research
Liang Shen, Hui-Hui Jiang, Hong-Fang Ji
Background: As the major active component of turmeric (Curcuma longa), curcumin is widely used as a spice and food coloring agent, and also possesses multiple biological activities and therapeutic potential for neurodegenerative diseases. To answer the paradox between curcumin's biological activities and poor systemic bioavailability, we proposed that degradation products of curcumin may make important contributions to its biological activities, which needs to be verified. In addition, curcumin is usually heated or boiled used as a spice, it is necessary to explore whether boiled curcumin, which degrades readily, is still biologically active...
2018: Food & Nutrition Research
Susan G Woods, Allen Knehans, Sandra Arnold, Carol Dionne, Leah Hoffman, Peggy Turner, Jonathan Baldwin
Background: Research on aging in Prader-Willi syndrome (PWS) is limited, although people with PWS are living longer. Individuals with PWS present with high fat mass, low lean mass, and low levels of physical activity (PA). Previous reports in children and young adults with PWS show inadequate nutrient intake and body fat percentage indicating obesity. Previous studies in PWS rarely included individuals beyond young adulthood, especially studies conducted in the United States. This study includes adults from 18 to 62 years of age, and includes 19 of the estimated 60 adult individuals with PWS in Oklahoma...
2018: Food & Nutrition Research
Yao Jiang, Chuhan Fu, Guihua Liu, Jiao Guo, Zhengquan Su
Background: Chitooligosaccharide (COS) has shown potential antihyperlipidemic activity in a few studies as a functional food. Method: We investigated the cholesterol-lowering effect and potential mechanisms of chitooligosaccharide capsules (COSTC) in male SD rats fed a high-fat diet. Results: COSTC could ameliorate serum lipid levels. Simultaneously, the cholesterol-lowering effect is probably attributed to its role in two pathways: upregulating the gene expression and activity of cholesterol 7α-hydroxylase (CYP7A1), liver X receptor alpha (LXRA), and peroxisome proliferation activated receptor-α (PPARα), which facilitates the conversion of cholesterol into bile acid; downregulating the gene expression and activity of enzymes including 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) and sterol-responsive element binding protein-2 (SREBP2) and upregulating the low-density lipoprotein receptor (LDLR) to reduce the denovo synthesis of cholesterol...
2018: Food & Nutrition Research
Liu Xianchu, Liu Ming, Liu Xiangbin, Zheng Lan
Background: Grape seed proanthocyanidin extract (GSPE) has been extensively reported to possess a wide range of beneficial properties in multiple tissue damage. Previous studies have shown that exhaustive exercise-induced fatigue associates with oxidative stress injury, inflammatory response, and mitochondrial dysfunction. Objective: The aim of this study is to investigate the anti-fatigue effects of GSPE in mice and explore its possible underlying mechanism. Design: The mouse model of exhaustive exercise-induced fatigue was established by using the forced swimming test, and GSPE was orally treated for successive 28 days at 0, 1, 50 and 100 mg/kg/day of body weight, designated the control, GSPE-L, GSPE-M and GSPE-H groups, respectively...
2018: Food & Nutrition Research
Svein Olav Kolset, Marianne Nordstrøm, Sigrun Hope, Kjetil Retterstøl, Per Ole Iversen
Persons with intellectual disabilities (ID) are dependent on nutritional policies that have so far not been addressed in a systematic and health-promoting manner in Norway and other nations with a high socioeconomic standard. In many poor countries, such issues have not even been raised nor addressed. Nutritional issues facing persons with ID include the risk of both underweight and overweight. Deficiency in energy, vitamins, essential fatty acids and micronutrients can increase the risk of additional health burdens in already highly vulnerable individuals...
2018: Food & Nutrition Research
Jiang Wu, Yan Zhong, Xiuhua Shen, Kefeng Yang, Wei Cai
Background: Recent studies have shown that vitamin D deficiency may contribute to the high prevalence of food allergy but the underlying mechanisms are far from clear. Objective: The present study was designed to investigate the effect of maternal and early-life vitamin D deficiency in the development of food allergy. Design: BALB/c mice were treated with ovalbumin (OVA) to trigger allergic reactions, under vitamin D-deficient (by maternal and early-life feeding of vitamin D deprived chow diet) or vitamin D-sufficient conditions...
2018: Food & Nutrition Research
Ive Nerhus, Maria Wik Markhus, Bente M Nilsen, Jannike Øyen, Amund Maage, Elisabeth Rasmussen Ødegård, Lisa Kolden Midtbø, Sylvia Frantzen, Tanja Kögel, Ingvild Eide Graff, Øyvind Lie, Lisbeth Dahl, Marian Kjellevold
Iodine is a trace element required for the production of thyroid hormones, essential for metabolism, growth and brain development, particularly in the first trimester of pregnancy. Milk and lean fish are the main dietary sources of iodine in the Norwegian diet. Thus, the aim of the present study was to provide updated analysed values of iodine concentration in six fish species, 27 selected Norwegian iodine-rich dairy foods and Norwegian hen's eggs. The iodine concentrations in the wild fish species varied between 18 μg/100 g (Atlantic halibut) and 1,210 μg/100 g (pollack)...
2018: Food & Nutrition Research
Yu-Si Liang, Wen-Tao Qi, Weiqun Guo, Chun-Ling Wang, Ze-Bin Hu, Ai-Ke Li
Aim: The purpose of this study was to investigate the possible mechanisms of genistein (GEN) and daidzein (DAI) in inducing apoptosis of colon cancer cells by inhibition of lipid droplets (LDs) accumulation. Methods: HT-29 cells were used and treated by GEN or DAI in this paper. LDs accumulation was induced and inhibited by oleic acid (OA) and C75, respectively. The expression changes of LDs-related markers were confirmed by semiquantitative real time-PCR (RT-PCR), Western blotting, and immunofluorescence staining...
2018: Food & Nutrition Research
Conrad Murendo, Brighton Nhau, Kizito Mazvimavi, Thamsanqa Khanye, Simon Gwara
Background: Nutrition education is crucial for improved nutrition outcomes. However, there are no studies to the best of our knowledge that have jointly analysed the roles of nutrition education, farm production diversity and commercialization on household, women and child dietary diversity. Objective: This article jointly analyses the role of nutrition education, farm production diversity and commercialization on household, women and children dietary diversity in Zimbabwe...
2018: Food & Nutrition Research
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2018: Food & Nutrition Research
Stina Engelheart, Robert Brummer
Background: There is no accepted or standardized definition of 'malnutrition'. Hence, there is also no definition of what constitutes an adequate nutritional status. In elderly people, assessment of nutritional status is complex and is complicated by multi-morbidity and disabilities combined with nutrition-related problems, such as dysphagia, decreased appetite, fatigue, and muscle weakness. Objective: We propose a nutritional status model that presents nutritional status from a comprehensive functional perspective...
2018: Food & Nutrition Research
Holly L Rippin, Jayne Hutchinson, Charlotte E L Evans, Jo Jewell, Joao J Breda, Janet E Cade
Objectives: The objectives of this study were (1) to determine the coverage of national nutrition surveys in the 53 countries monitored by the World Health Organization (WHO) Regional Office for Europe and identify gaps in provision, (2) to describe relevant survey attributes and (3) to check whether energy and nutrients are reported with a view to providing information for evidence-based nutrition policy planning. Design: Dietary survey information was gathered using three methods: (1) direct email to survey authors and other relevant contacts, (2) systematic review of literature databases and (3) general web-based searches...
2018: Food & Nutrition Research
Huandong Zhao, Jian Li, Juan Zhao, Yang Chen, Caiping Ren, Yuxiang Chen
Background: Many plant original foods have been shown beneficial effects in humans. In the previous work, we have developed a compound capsule which contains major constituents of walnut oil and grape seed extract. Objective: To investigate the antioxidant effects of the Compound Walnut Oil Capsule (WOC) in aging model induced by D-gal. Design: 70 C57BL/6J mice were randomly divided into seven groups. Mice in normal group received daily subcutaneous injection of saline while the control group, WOC groups, Vitamin C (VC) group and pure walnut oil group received daily subcutaneous injection of D-galactose (D-gal) for 8 weeks...
2018: Food & Nutrition Research
Karianne Svendsen, Hege Berg Henriksen, Beate Østengen, David R Jacobs, Vibeke H Telle-Hansen, Monica H Carlsen, Kjetil Retterstøl
Background: The Vascular lifestyle-Intervention and Screening in phArmacies (VISA) study investigates diet and lifestyle factors associated with risk of cardiovascular disease (CVD). As part of the study methodology, a short Food Frequency Questionnaire (FFQ), the VISA-FFQ, was adapted from the Norwegian NORDIET-FFQ. Objective: The aim of this study was to evaluate the VISA-FFQ and its ability to estimate intakes of foods and lifestyle factors in screening for elevated risk of CVD...
2018: Food & Nutrition Research
Xirun Liu, Shanshan Huang, Wangdong Xu, Aijing Zhou, Hui Li, Rong Zhang, Ya Liu, Yan Yang, Hong Jia
Background: Diet plays an important role in the development of hyperuricemia (HUA), but evidence for association between overall dietary patterns and HUA is scarce and inconsistent. The present study aims to explore association of dietary patterns and HUA among the Yi ethnic group of China. Methods: This is a cross-sectional study involving people aged more than 18 years. Principal component factor analysis (PCFA) on food groups from a semi-quantitative 52-item food frequency questionnaire was applied to identify dietary patterns...
2018: Food & Nutrition Research
Bodil Ohlsson, Gassan Darwiche, Bodil Roth, Peter Höglund
Background: An Okinawa-based Nordic diet with moderately low carbohydrate content and high fat and protein content has been shown to improve anthropometry and metabolism in type 2 diabetes. Objective: The objectives of this study were to measure plasma or serum levels of hormones regulating energy metabolism and metabolic control, that is, cholecystokinin (CCK), Cortisol, C-peptide, ghrelin, glucagon, glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), insulin, leptin, plasminogen activator inhibitor-1 (PAI-1), polypeptide YY (PYY), resistin, and visfatin after this diet intervention, and to determine partial correlations between hormonal levels and anthropometric and metabolic responses...
2018: Food & Nutrition Research
Elizabeth A Wood, Katharine McNamara, Agata Kowalewska, Nargiza Ludgate
This study was conducted to research and develop recommendations for gender transformative approaches that will address misconceptions around food and nutrition, and reducing barriers around dietary diversity within rural Khatlon Province, Tajikistan. Most of the population in Tajikistan live in rural areas and spend a large part of their income on food. While stunting in children under 5 years has decreased, acute malnutrition and the number of underweight children has increased. This is a qualitative, cross-sectional study that involved secondary data analysis, key informant interviews (KIIs), and focus group discussions (FGDs) to gauge appropriate interventions for agricultural extension agents seeking to improve the nutritional outcomes of their communities...
2018: Food & Nutrition Research
Zhu Yi-Shen, Sun Shuai, Richard FitzGerald
To date, no extensive literature review exists regarding potential uses of mung bean proteins and peptides. As mung bean has long been widely used as a food source, early studies evaluated mung bean nutritional value against the Food and Agriculture Organization of the United Nations (FAO)/the World Health Organization (WHO) amino acids dietary recommendations. The comparison demonstrated mung bean to be a good protein source, except for deficiencies in sulphur-containing amino acids, methionine and cysteine...
2018: Food & Nutrition Research
BoYoon Chang, BongSeong Koo, HyeonCheol Lee, Joa Sub Oh, SungYeon Kim
Background: The innate immune system plays a crucial role in the initiation and subsequent direction of adaptive immune responses, as well as in the removal of pathogens that have been targeted by an adaptive immune response. Objective: Morus alba L. was reported to have immunostimulatory properties that might protect against infectious diseases. However, this possibility has not yet been explored. The present study investigated the protective and immune-enhancing ability of M...
2018: Food & Nutrition Research
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