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ARYA Atherosclerosis

Mohsen Yaghubi, Hossein Dinpanah, Fahimeh Ghanei-Motlagh, Samaneh Kakhki, Reza Ghasemi
BACKGROUND: Amyloidosis is a severe systemic disorder produces by the accumulation of inappropriately amyloid deposition in tissues. Cardiac involvement, as a main type of amyloidosis, has a major impact on prognosis. We describe a biopsy-proven cardiac amyloidosis in an old man with unexpected presentation. CASE REPORT: A 70-year-old man, with a complaint of severe weakness, lightheadedness, and lower limb paresthesia, was admitted to the emergency department. Electrocardiography revealed right bundle branch block and Trifascicular block...
March 2018: ARYA Atherosclerosis
Farshad Roghani-Dehkordi, Omid Hashemifard, Masoumeh Sadeghi, Rohollah Mansouri, Mehdi Akbarzadeh, Asieh Dehghani, Mojtaba Akbari
BACKGROUND: Trans-radial and trans-ulnar accesses have been practiced and recommended as default and alternative techniques for coronary angiography and angioplasty in recent years. In this study, we present new innovative approaches using more distal access points, i.e. trans-snuff box and trans-palmar approaches. METHODS: We conducted dorsal hand access (trans-snuff box) for angiography and/or angioplasty on 235 patients, and trans-palmar access (superficial palmar branch of ulnar artery) on 175 patients in 3 hospitals in Isfahan City, Iran...
March 2018: ARYA Atherosclerosis
Masoumeh Sadeghi, Hossein Khosravi-Broujeni, Amin Salehi-Abarghouei, Ramin Heidari, Gholamreza Masoumi, Hamidreza Roohafza
BACKGROUND: This systematic review and meta-analysis aimed to assess the effect of cardiac rehabilitation (CR) on serum C-reactive protein (CRP) as an indicator of the inflammatory state and predictor of recurrent cardiovascular events. METHODS: PubMed, SCOPUS, Cochrane library, and Google Scholar databases were searched up to January 2014 for original articles which investigated the effect of CR on CRP among adult patients with previous cardiovascular events. The random effects model was used to assess the overall effect of CR on the variation in serum CRP levels...
March 2018: ARYA Atherosclerosis
Javad Shahabi, Reihaneh Zavar, Afshin Amirpour, Mohammad Bidmeshki, Melinaz Barati-Chermahini
BACKGROUND: Acute pulmonary thromboembolism (PTE) is a common disease with a high mortality rate, and a variable and nonspecific clinical presentation. To detect the nonspecific signs and symptoms associated with this condition, several right ventricular (RV) echocardiographic parameters have been proposed as practical marker. METHODS: This cross-sectional study was performed on 93 patients with PTE diagnosed by computed tomography (CT) angiography, and 57 patients with negative PTE based on CT angiography...
March 2018: ARYA Atherosclerosis
Fereshteh Asgharzadeh, Rahimeh Bargi, Mahmoud Hosseini, Mehdi Farzadnia, Majid Khazaei
BACKGROUND: Subclinical inflammation induced by persistent exposure to lipopolysaccharide (LPS) is found in some clinical conditions such as obesity or diabetes. This study aimed to investigate the effect of recurrent LPS exposure on inflammatory markers, oxidative stress balance and cardiac and renal fibrosis in male rats. METHODS: Male Wistar rats were divided into control and LPS-treated. LPS (10 mg/kg/week) was injected intraperitoneally. After 4 weeks, left ventricles and kidneys were homogenized and stained with hematoxylin and eosin (H&E) and Masson trichrome for histological examination...
March 2018: ARYA Atherosclerosis
Fatemeh Nouri, Awat Feizi, Noushin Mohammadifard, Nizal Sarrafzadegan
BACKGROUND: The aim of this study was describing the sampling methods and sample size of the Isfahan Healthy Heart Program (IHHP) and its sub-studies in focus. METHODS: The IHHP was carried out between 2000 and 2007 in urban and rural areas in 3 districts, namely Isfahan and Najafabad (as the intervention areas), and Arak (as the reference area), Iran. It consisted of the 3 phases of baseline surveys during 2000-2001, interventions between 2002 and 2005, and post-intervention surveys during 2006-2007 on 4 target groups (adults, health professionals, cardiac patients, children, and adolescents)...
March 2018: ARYA Atherosclerosis
Fazele Atarbashi-Moghadam, Seyed Rohollah Havaei, Seyed Asghar Havaei, Nafiseh Sadat Hosseini, Gholamreza Behdadmehr, Saede Atarbashi-Moghadam
BACKGROUND: Atherosclerosis and periodontitis are both chronic inflammatory diseases. Although a strong relationship between the two has already been established, the underlying mechanism is unknown. The present study was conducted aiming to detect the deoxyribonucleic acid (DNA) of Aggregatibacter actinomycetemcomitans (A.a), Campylobacter rectus (C.r), and Porphyromonas gingivalis (P.g) in subgingival and atherosclerotic plaques of patients with both chronic periodontitis and cardiovascular disease (CVD)...
March 2018: ARYA Atherosclerosis
Beydolah Shahouzehi, Hamid Reza Nasri, Yaser Masoumi-Ardakani
BACKGROUND: Thalassaemia is a hereditary disorder and has an economic burden on patients and the government. The most prevalent complication in these patients is iron overload which is followed by cardiomyopathy. Digoxin is considered as a treatment against heart failure in thalassaemia. The present study evaluated the effect of two digoxin concentrations on iron content and antioxidative defense in cardiac tissue of iron-overloaded rats. METHODS: The study was conducted on 48 rats which were divided into 6 groups...
March 2018: ARYA Atherosclerosis
Saeid Komasi, Ali Soroush, Mozhgan Saeidi
No abstract text is available yet for this article.
January 2018: ARYA Atherosclerosis
Leili Iranirad, Mohammad Saleh Sadeghi
BACKGROUND: Coronary artery spasm (CAS) can result in life-threatening arrhythmia and sudden cardiac death. Although this disorder has been known for a long time, little is known about it, and its mechanisms have been not identified yet. CASE REPORT: We describe a 52-year-old woman with no significant cardiovascular risk factors who experienced several episodes of spontaneous and coincident multivessel coronary artery spasm, which led to myocardial infarction as well as malignant arrhythmias...
January 2018: ARYA Atherosclerosis
Mahdi Kahrom, Mostafa Ahmadi, Behrooz Mottahedi, Masoomeh Tabari, Atieh Vatanchi, Naser Paravi, Hamid Ghaderi
BACKGROUND: Critical aortic stenosis (AS) is an unusual cardiac pathology in pregnancy, but has significant impact on the fetal and maternal outcomes of pregnancy. Pregnant patients with aortic stenosis and heart failure represent a major challenge for the heart team and anesthesiologist who should balance the risks and benefits of different treatment strategies and their effects on the mother and fetus. CASE REPORT: We present a 26-year-old parturient who underwent cesarean section at 30 weeks of gestation under general anesthesia in the presence of cardiac surgical team followed by deferred aortic valve replacement after two weeks...
January 2018: ARYA Atherosclerosis
Ali Nasri, Jamshid Najafian, Seied Majid Derakhshandeh, Faezeh Madjlesi
BACKGROUND: Clinical imaging studies have demonstrated a strong direct correlation between epicardial fat and abdominal visceral adiposity. There are several studies about positive correlation of epicardial fat and atherosclerotic coronary disease in general population. This study aimed to evaluate the association of epicardial fat thickness with atherosclerotic coronary disease in patients with diabetes mellitus type II. METHODS: This cross-sectional observational study involved 80 patients with diabetes mellitus type II...
January 2018: ARYA Atherosclerosis
Mohammad Hasan Entezari, Rasol Salehi, Mohammad Kazemi, Mohsen Janghorbani, Marzieh Kafeshani
BACKGROUND: Peroxisome proliferator-activated receptor gamma (PPAR-γ) which controls body weight, glucose homeostasis, and adipocyte differentiation is a valuable candidate gene for insulin resistance (IR). The present study aimed to compare the effects of the Dietary Approaches to Stop Hypertension (DASH) diet and usual dietary advice (UDA) on PPAR-γ gene expression in women at risk for cardiovascular disease (CVD). METHODS: This randomized controlled trial was performed on 44 women aged 20-50 years at risk for CVD (BMI > 25 kg/m2 and low physical activity)...
January 2018: ARYA Atherosclerosis
Fereshteh Ghaderi, Farveh Vakilian, Pouya Nezafati, Omid Reza Amini, Mohammad Sobhan Sheikh-Andalibi
BACKGROUND: Differentiating ischemic from non-ischemic functional mitral regurgitationý (FMR) in patients with cardiomyopathy is important in terms of the therapeutic decision-making and prognosis, but might be clinically challenging. In this study, the deformation of mitral valve (MV) indices in the prediction of the etiology of FMR was assessed using 2D transthoracic and tissue Doppler echocardiography. METHODS: This case-control study was conducted from April 2015 to January 2016 in Imam Reza Hospital in Mashhad, Iran...
January 2018: ARYA Atherosclerosis
Davoud Kazemisaleh, Keivan Kiani, Masoumeh Sadeghi, Hamidreza Roohafza, Minoo Dianatkhah, Nizal Sarrafzadegan
BACKGROUND: Vitamin D deficiency is a prevalent condition in Iran and previous studies have shown that a low level of serum vitamin D is related to low ankle-brachial index (ABI). In the present study, the relationship of the serum level of vitamin D with ABI, as an index for atherosclerosis of peripheral arteries, was evaluated. METHODS: In this cross-sectional study, data on 91 patients with metabolic syndrome (Mets) from the Isfahan Cohort Study (ICS) were analyzed in order to evaluate the association between serum 25(OH) vitamin D level and ABI...
January 2018: ARYA Atherosclerosis
Maryam Esfahani, Masoud Saidijam, Rezvan Najafi, Mohammad Taghi Goodarzi, Ahmad Movahedian
BACKGROUND: Atherosclerosis is one of the predominant causes of cardiovascular disease (CVD). Several studies indicated the significant pathophysiological role of salusin-β in atherosclerosis. Cytokines are involved in all stages of atherosclerosis. Therefore, we aimed to assess the effect of salusin-β on interleukin 6 (IL-6), interleukin 8 (IL-8), interleukin 18 (IL-18) (as inflammatory cytokines) and interleukin 1Ra (IL-1Ra) (as anti-inflammatory cytokines) levels in human umbilical vein endothelial cells (HUVECs)...
January 2018: ARYA Atherosclerosis
Mahdi Najafi-Dalui, Hasan Shemirani, Reyhaneh Zavar, Ali Eghbal
BACKGROUND: Atrial fibrillation (AF) is the most common tachyarrhythmia and an important risk factor for thromboembolic stroke. CHA2DS2-VASc score was introduced for assessment of embolic events and as criteria for starting anticoagulants. This study was performed to evaluate the left ventricular diastolic dysfunction (LVDD) in patients with non-hemorrhagic stroke and AF. METHODS: This cross-sectional study consisted of 76 consecutive patients with suspected non-hemorrhagic stroke referred to the Cardiology Department of Alzahra and Ayatollah Kashani hospitals in Isfahan, Iran, during 2015-2016...
November 2017: ARYA Atherosclerosis
Niloufar Samiei, Hooman Dehghan, Maryam Pourmojib, Ahmad Mohebbi, Saeid Hosseini, Yousef Rezaei
BACKGROUND: Double-orifice mitral valve (DOMV) is an extremely rare cardiac malformation. It has been found to be accompanied by congenital anomalies (CAs), however, it can be detected as an isolated anomaly. The clinical findings of a DOMV are variable and depend predominantly on the associated cardiac abnormalities, particularly atrioventricular septal defects or mitral valve (MV) regurgitation and/or stenosis. CASE REPORT: In this regard, we describe an isolated DOMV in an 18-year-old young girl who complained of a short-term nonspecific chest pain...
November 2017: ARYA Atherosclerosis
Fatemeh Bazyar, Mohammad Gholami-Fesharaki, Mohsen Rowzati
BACKGROUND: There is a small number of studies that considered the relationship between shift work (SW) and Framingham risk score (FRS). This study prospectively examined the association between SW and FRS among man workers based on the multilevel modeling approach. METHODS: This five-year prospective cohort study was done among workers (using stratified random sampling) who work in Esfahan's Mobarakeh Steel Company (EMSC), Iran, from March 2011 to February 2015...
November 2017: ARYA Atherosclerosis
Gholamreza Shahsavari, Amir Raoufi, Aram Toolabi, Nahid Hosseninejadmir, Hassan Ahmadvand, Mehdi Safariebrahimsarabie
BACKGROUND: The major aim of this study was evaluating the effect of atorvastatin treatment on thiobarbituric acid reactive substances (TBARS), ferric reducing the ability of plasma (FRAP), small dense low-density lipoprotein cholesterol (sdLDL) and lipid profile in coronary artery disease (CAD) patients. METHODS: This study was carried out on 83 patients with angiographically proven coronary artery stenosis (52 men and 31 women) at Shahid Madani Hospital, Khorramabad, Iran, in 2015...
November 2017: ARYA Atherosclerosis
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