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Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment

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https://www.readbyqxmd.com/read/30016205/in-vitro-model-to-assess-the-adsorption-of-oral-veterinary-drugs-to-mycotoxin-binders-in-a-feed-and-aflatoxin-b1-containing-buffered-matrix
#1
Siegrid De Baere, Thomas De Mil, Gunther Antonissen, Mathias Devreese, Siska Croubels
Mycotoxin binders are feed additives which are mixed in the feed to adsorb mycotoxins and thereby reducing their toxic effects on animals. Interactions with orally administered veterinary medicinal products, such as antimicrobials or coccidiostats, have been reported previously. This paper describes an in vitro model to screen the interaction between mycotoxin binders and veterinary drugs with respect to the non-specific binding of drugs. It is designed as a static setup using a single concentration of drug and binder in a feed-containing or a feed-plus-mycotoxin-containing matrix, buffered at different pH values...
July 17, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/30016195/antifungal-effect-of-organic-acids-from-lactic-acid-bacteria-on-penicillium-nordicum
#2
Ana Guimarães, Armando Venâncio, Luís Abrunhosa
The control of fungal contamination is particularly important to avoid both spoilage of food and feed products and also the occurrence of toxic compounds, known as mycotoxins. Some Lactic acid bacteria (LAB) strains have shown the capacity to inhibit fungal growth and the production of mycotoxins. In this work, cell-free supernatants (CFS) of Lactobacillus plantarum UM55 and Lactobacillus buchneri UTAD104 were tested against Penicillium nordicum radial growth and ochratoxin A (OTA) production. When cell-free supernatants (CFS) of these strains were used, the radial growth of the fungus was inhibited by less than 20%, but the production of OTA was reduced by ca 60%...
July 17, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/30016190/evaluation-of-short-chain-chlorinated-paraffins-in-human-milk-and-their-intake-by-infants-in-hebei-province-china
#3
Lixin Yang, Ziyuan Wang, Jianguo Li, Yuxia Ma, Lingxiong Kong, Hui Yang, Liying Wang, Yinping Liu, Yang Lu, Jianbo Zhang
Short-chain chlorinated paraffins (SCCPs) have drawn increasing interest worldwide since they were included in the list of controlled persistent organic pollutants in Annex A of the Stockholm Convention in 2017, and the potential health risk they pose to humans must be evaluated. In this study, 86 human milk samples were collected from 55 healthy Chinese mothers living in the Shijiazhuang region of Northern China in 2014-2015. Advanced online gel permeation chromatography-gas-chromatography-coupled mass spectrometry with negative-ion chemical ionization was used to quantify the SCCPs in the samples...
July 17, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29889654/assessment-of-cytotoxic-and-genotoxic-effects-of-enniatin-a-in-vitro
#4
Sevcan Mamur, Deniz Yuzbasioglu, Serkan Yılmaz, Esra Erikel, Fatma Unal
Enniatin A (EN-A) is a Fusarium mycotoxin which is a common contaminant in grains and especially in maize and it causes serious loss of product. The aim of this study was to investigate the cytotoxic effects using 3-(4,5-dimethylthiazolyl-2)-2,5 diphenyltetrazolium bromide (MTT) assay in human cervix carcinoma (HeLa) cell line, and genotoxic effects of EN-A using chromosome aberrations (CAs), sister chromatid exchanges (SCEs), micronuclei (MN) and comet assays in human lymphocytes. The cells were treated with 0...
July 16, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29999471/modelling-the-long-term-feed-to-fillet-transfer-of-leuco-crystal-violet-and-leuco-malachite-green-in-atlantic-salmon-salmo-salar
#5
Marc Hg Berntssen, Rita Hannisdal, Louise Buttle, Rudolf Hoogenveen, Marcel Mengelers, Bas Gh Bokkers, Marco J Zeilmaker
Leuco crystal violet (LCV) and leuco malachite green (LMG) are the main metabolites of two dyes that are forbidden for use in food production, but can be present at low background concentration in novel Atlantic salmon feed ingredients such as processed animal proteins (ABP). In this study, the potential transfer of dietary LCV or LMG to the fillet of farmed Atlantic salmon was investigated. The uptake and elimination rate kinetics were determined in seawater-adapted Atlantic salmon (initial weight 587 ± 148 g) fed two levels of either LCV or LMG enriched diets (~500 and 4000 µg kg-1 , respectively) for 40 days, followed by a 90 days depuration period with feeding on control diets (< 0...
July 12, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29995588/magnetic-nanocellulose-hybrid-nanoparticles-and-ionic-liquid-for-extraction-of-neonicotinoid-insecticides-from-milk-samples-prior-to-determination-by-liquid-chromatography-mass-spectrometry
#6
Carlos Adelantado, Ángel Ríos, Mohammed Zougagh
A simple and rapid microextraction procedure is reported on the use of ionic liquid in combination with magnetic nanocellulose hybrid nanoparticles. The procedure is ultrasound-assisted and applicable to selective preconcentration of neonicotinoid insecticides from milk samples, prior to being analysed by liquid chromatography-mass spectrometry. The extraction procedure uses small volume of organic solvents (<1 mL), and there is no need for centrifugation. In the experimental approach the ionic liquid was quickly disrupted by an ultrasonic probe and dispersed in milk samples in a cloudy form...
July 11, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29989848/when-lc-hrms-metabolomics-gets-iso17025-accredited-and-ready-for-official-controls-application-to-the-screening-of-forbidden-compounds-in-livestock
#7
Gaud Dervilly-Pinel, Anne-Lise Royer, Elena Bozetta, Marzia Pezzolato, Loïc Herpin, Stéphanie Prevost, LE Bizec Bruno
Within the particular context of controlling chemical residues in food, an alternative to targeted approaches has emerged; it consists in the characterization of physiological perturbations induced upon exposure of animals to a given chemical substance/class of substances to highlight suitable biomarkers addressing safety and/or regulatory issues. Metabolomics in particular has been investigated in the hope of identifying such biomarkers, and a range of studies have demonstrated the efficiency of the strategy...
July 10, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29975171/selective-adsorption-and-separation-of-illegal-cationic-dyes-from-foodstuffs-with-anionic-polyelectrolyte-functionalization-of-metal-organic-frameworks
#8
Xue Wang, Hui-Ling Duan, Shi-Yao Ma, Jun Wang, Han-Ying Zhan, Zhi-Qi Zhang
A novel adsorbent, poly(sodium 4-styrenesulfonate) modified MIL-101(Cr)-NH2 , was successfully prepared. Owing to its high surface area and degree of negative surface charge, it enables effective adsorption and separation of illegal cationic dyes, such as rhodamine B, pararosaniline, and auramine O, from foodstuffs prior to high performance liquid chromatography analysis. Under optimized conditions, good linearity was obtained over 1.0-80.0 or 1.0-120 ng mL-1 with a correlation coefficient (R2 ) >0.999. Limits of detection and limits of quantification of the three dyes were 0...
July 5, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29873606/parameters-affecting-5-hydroxymethylfurfural-exposure-from-beer
#9
Olga Viegas, Mafalda Prucha, Vural Gökmen, Isabel M P L V O Ferreira
5-Hydroxymethylfurfural (HMF) is generated during food and beverage heating processes and/or storage. Its daily intake, estimated as 4-10 mg day-1 , is several orders of magnitude higher than other process contaminants. Beer can be of relevance to the evaluation of HMF exposure; however, the information concerning its occurrence in different types of beer and during product storage is scarce. Therefore, the major goal of this work was to assess the amounts of HMF in different commercial beers, as well as the impact of storage, to deepen knowledge about the contribution of beer to HMF exposure...
June 25, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29843576/dietary-intake-of-dioxins-in-japan-in-2016-with-time-trends-since-1998
#10
Tomoaki Tsutsumi, Rieko Matsuda, Toshihiko Yanagi, Seiichiro Iizuka, Satoshi Isagawa, Satoshi Takatsuki, Takahiro Watanabe, Reiko Teshima, Hiroshi Akiyama
Total diet samples collected from seven regions throughout Japan in 2016 were analysed for polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and dioxin-like polychlorinated biphenyls (DL-PCBs), known collectively as dioxins. This led to estimates of the latest dietary intake of these contaminants for the general Japanese population (≥1 year old). The average daily intake of dioxins for a person weighing 50 kg, calculated at non-detected congener concentrations assumed to be equal to zero, was estimated to be 0...
June 25, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29843566/urinary-aflatoxin-exposure-monitoring-in-rural-and-semi-urban-populations-in-ogun-state-nigeria
#11
Chibundu N Ezekiel, Oyetunde T Oyeyemi, Oluwawapelumi A Oyedele, Kolawole I Ayeni, Ifeoluwa T Oyeyemi, Williams Nabofa, Chinomso U Nwozichi, Adeyemi Dada
Aflatoxins are a major class of fungal toxins that have food safety importance due to their economic and health impacts. This pilot aflatoxin exposure biomonitoring study on 84 individuals was conducted in a rural (Ilumafon) and a semi-urban community (Ilishan Remo) of Ogun state, Nigeria, to compare aflatoxin exposures among the two population cohorts. First morning urine samples were obtained from the participants, and the urinary aflatoxin M1 (AFM1 ) levels were measured by a quantitative Helica Biosystems Inc...
June 19, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29787353/survey-of-roasted-street-vended-nuts-in-sierra-leone-for-toxic-metabolites-of-fungal-origin
#12
Julius I N Sombie, Chibundu N Ezekiel, Michael Sulyok, Kolawole I Ayeni, Felixtina Jonsyn-Ellis, Rudolf Krska
Consumption of mycotoxin contaminated foodstuffs is common in regions where foods are not adequately controlled and routinely monitored, and this could have adverse effects on the health of consumers. In this study, 100 samples of roasted nuts (50 cashew nuts and 50 peanuts) vended within two cities of Sierra Leone were analysed for mycotoxins and other microbial metabolites by a LC-MS/MS method. The peanut samples contained detectable levels of 17 microbial metabolites, including aflatoxins B1 , B2 , G1 and G2 and alternariol, while none of these metabolites were found in the cashew samples...
June 19, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29775427/determination-of-fipronil-and-its-metabolites-in-chicken-egg-muscle-and-cake-by-a-modified-quechers-method-coupled-with-lc-ms-ms
#13
Qiaozhen Guo, Shan Zhao, Jing Zhang, Kailun Qi, Zhenxia Du, Bing Shao
An easy-to-use method for determining the levels of fipronil and its metabolites (fipronil-desulfinyl, fipronil-sulfone and fipronil-sulfide) in chicken egg, muscle and cake was developed and validated using a modified quick, easy, cheap, effective, rugged and safe (QuEChERS) approach coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis. The samples were extracted using acetonitrile, salted out with sodium chloride at -20°C, and then purified by combined PSA and C18 phases and anhydrous magnesium sulphate...
June 19, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29913103/inhibitory-effect-of-mixture-herbs-spices-on-formation-of-heterocyclic-amines-and-mutagenic-activity-of-grilled-beef
#14
Shabnam Sepahpour, Jinap Selamat, Alfi Khatib, Mohd Yazid Abdul Manap, Ahmad Faizal Abdull Razis
Natural antioxidants in spices and herbs have attracted considerable attention as potential inhibitors against the formation of mutagenic heterocyclic amines (HCAs) in heat processed meat. In this study, the inhibitory activity of four spices/herbs and their mixtures on HCAs formation in grilled beef were examined. A simplex centroid mixture design with four components comprising turmeric, curry leaf, torch ginger and lemon grass in 19 different proportions were applied on beef samples before grilling at 240 ºC for 10 min...
June 18, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29912678/game-meat-consumption-by-hunters-and-their-relatives-a-probabilistic-approach
#15
Jesus Sevillano Morales, Alicia Moreno-Ortega, Manual Angel Amaro Lopez, Antonio Arenas Casas, Fernando Cámara-Martos, Rafael Moreno-Rojas
This study aimed to estimate the consumption of meat and products derived from hunting by the consumer population and, specifically, by hunters and their relatives. For this purpose, a survey was conducted on the frequency of consuming meat from the four most representative game species in Spain, two of big game, wild boar (Sus scrofa) and red deer (Cervus elaphus) and two of small game, rabbit (Oryctolagus cunulucus) and red partridge (Alectoris rufa), as well as of processed meat products (salami-type sausage) made from those big game species...
June 18, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29912642/investigation-of-the-potential-for-a-simplified-exposure-tool-in-medical-nutrition-setim-to-minimise-exposures-to-sweeteners-in-young-patients-aged-1-3-years-with-pku-and-cmpa
#16
Aaron J O'Sullivan, Cian O'Mahony, Leo Meunier, Nik Loveridge, Aideen I McKevitt
Children with Phenylketonuria (PKU) and severe cow's milk protein allergy (CMPA) consume prescribed, specially formulated, foods for special medical purposes (FSMPs) in addition to having restricted intake of normal foods. These vulnerable patients are exposed to artificial sweeteners from the consumption of a combination of both free and prescribed foods. Young patients with PKU and CMPA aged from 1-3 years have a higher risk of exceeding the acceptable daily intake (ADI) for sweeteners than age-matched healthy children...
June 18, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29912639/evaluation-of-aflatoxins-and-aspergillus-sp-contamination-in-raw-peanuts-and-peanut-based-products-along-the-supply-chain-in-malaysia
#17
Mahror Norlia, M A R Nor-Khaizura, Jinap Selamat, Fatimah Abu Bakar, Son Radu, Cheow Keat Chin
The peanut supply chain in Malaysia is dominated by three main stakeholders (importers, manufacturers, retailers). The present study, aimed to determine the levels and critical points of aflatoxins and fungal contamination in peanuts along the supply chain. Specifically, two types of raw peanuts and six types of peanut-based products were collected (N = 178). Samples were analysed for aflatoxins by using High Performance Liquid Chromatography. Results revealed that the aflatoxins contamination was significantly higher (P≤0...
June 18, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29912638/mycotoxin-contamination-of-sorghum-and-its-contribution-to-human-dietary-exposure-in-four-sub-saharan-countries
#18
Geoffrey Ssepuuya, Christof Van Poucke, Emmanuel Njumbe Ediage, Catherine Mulholland, Angelika Tritscher, Philippe Verger, Mary Kenny, Catherine Bessy, Sarah De Saeger
This research aimed at evaluating the safety, and the type, level and prevalence of mycotoxins in grain sorghum of four sub-Saharan African (SSA) countries (Burkina Faso, Ethiopia, Mali and Sudan). A multi-analyte LC-MS/MS method for quantification of 23 mycotoxins (nivalenol, deoxynivalenol, fusarenon X, neosolaniol, 3-acetyl deoxynivalenol, 15-acetyl deoxynivalenol, diacetoxyscirpenol, roquefortine C, HT-2 toxin, alternariol, T-2 toxin, FB1, FB2, FB3, zearalenone, aflatoxin G1 , aflatoxin G2 , aflatoxin B1 , aflatoxin B2 , sterigmatocystin, OTA, altenuene, alternariol monomethylether) was applied to different sorghum matrices...
June 18, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29856688/determination-of-benzo-%C3%AE-pyrene-in-edible-oil-using-tetraoxocalix-2-arene-2-triazine-bonded-silica-spe-sorbent
#19
Yun Guo, Wen-Jie Zhao, Zhi-Fen Deng, Hong-Bo Wang, Bin Peng, Xue Ma, Chen Lan, Shu-Sheng Zhang
Benzo[α]pyrene (BaP) is a well-known carcinogen in edible oil. In this study, a method combined solid-phase extraction (SPE) with fluorescent detection was developed using tetraoxocalix[2]arene[2]triazine sorbent (SiO2 -OCA) for the clean-up and enrichment of BaP. The interaction between SiO2 -OCA and BaP involves a donor-acceptor complex mechanism. The experimental procedure was as follows: BaP was extracted from edible oil with DMF/H2 O (9:1, v/v). Then, the ratio of DMF/H2 O was adjusted to 1:2 prior to SPE...
June 18, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29847212/determination-and-identification-of-titanium-dioxide-nanoparticles-in-confectionery-foods-marketed-in-south-korea-using-inductively-coupled-plasma-optical-emission-spectrometry-and-transmission-electron-microscopy
#20
Namhoon Kim, Changkyu Kim, Soyoung Jung, Youngae Park, Youngju Lee, Juyeon Jo, Misun Hong, Sangmi Lee, Younghee Oh, Kweon Jung
Food-grade titanium dioxide (TiO2 ) is a common and widespread food additive in many processed foods, personal care products, and other industrial categories as it boosts the brightness and whiteness of colours. Although it is generally recognised as safe for humans, there is a growing interest in the health risks associated with its oral intake. This study quantified and identified TiO2 nanoparticles present in confectionery foods, which are children's favourite foods, with inductively coupled plasma optical emission spectrometry (ICP-OES) and transmission electron microscopy (TEM)...
June 18, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
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