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Pediatrics and Neonatology

Elif Bahat Ozdogan, Mehmet Mutlu, Secil Arslansoyu Camlar, Gülcin Bayramoglu, Sebnem Kader, Yakup Aslan
BACKGROUND: It is controversial to test for urinary tract infection (UTI) in patients with unexplained indirect hyperbilirubinemia in the first 2 weeks of life. We aimed to study the prevalence and significance of UTIs in such neonates who were requiring phototherapy. METHODS: Subjects were 2- to 14-day-old neonates with indirect bilirubin levels above phototherapy limit with no other abnormality in their bilirubinaemia-related etiologic workup. UTI was diagnosed by 2 consecutive positive cultures obtained by catheterisation, documenting growth of >10,000 colonies of the same microorganism with consistent antibiograms...
October 28, 2017: Pediatrics and Neonatology
Hao-Yuan Lee, Cheng-Hsun Chiu
No abstract text is available yet for this article.
October 24, 2017: Pediatrics and Neonatology
Patryk Lipiński, Irena Jankowska, Agnieszka Ługowska, Małgorzata Musielak, Maciej Pronicki, Anna Tylki-Szymańska
No abstract text is available yet for this article.
October 12, 2017: Pediatrics and Neonatology
François Niada, René Tabin, Simon Kayemba-Kay's
Renal vein thrombosis (RVT) is a rare but well-known neonatal entity for which several therapeutic modalities are reported in the literature because of the lack of consensus management guidelines. POPULATION AND METHODS: A retrospective study of the medical records of children managed between January 1990 and December 2013, and whose final diagnosis was RVT. The diagnosis was initially clinical and subsequently confirmed by the abdominal ultrasonography (AUS) and Doppler imaging if necessary...
October 9, 2017: Pediatrics and Neonatology
Xuetao Mu, Zhiqun Wang, Binbin Nie, Shaofeng Duan, Qiaozhi Ma, Guanghui Dai, Chunnan Wu, Yuru Dong, Baoci Shan, Lin Ma
BACKGROUND: Very few studies have been made to investigate functional activity changes in occult spastic diplegic cerebral palsy (SDCP). The purpose of this study was to analyze whole-brain resting state regional brain activity and functional connectivity (FC) changes in patients with SDCP. METHODS: We examined 12 occult SDCP and 14 healthy control subjects using resting-state functional magnetic resonance imaging. The data were analyzed using Resting-State fMRI Data Analysis Toolkit (REST) software...
October 7, 2017: Pediatrics and Neonatology
Hao-Wei Chung, Wei-Te Lee, Hsiu-Lin Chen
BACKGROUND: The appropriate endotracheal tube (ET) depth for the newborn with respiratory failure is important. Inappropriate ET depth increases the risk of uneven lung expansion and collapse. This retrospective study aimed to compare the final ideal ET depth with Tochen's formula in Taiwanese intubated neonates, and to determine the correlation between neonatal factors and final ideal ET depth, and to devise an accurate predictive formula for use in Taiwan. METHODS: Data were collected from neonates who required endotracheal intubation and who were admitted to the Neonatal Intensive Care Unit from 2011 to 2015...
October 6, 2017: Pediatrics and Neonatology
Natasha Ali
Children routinely receive packed red blood transfusion when they are admitted in the intensive care unit or undergoing cardiac surgeries. These guidelines aim to summarize literature and provide transfusion triggers exclusively in infants and children.
October 6, 2017: Pediatrics and Neonatology
Geovanny F Perez, Bassem Kurdi, Rosemary Megalaa, Krishna Pancham, Shehlanoor Huseni, Natalia Isaza, Carlos E Rodriguez-Martinez, Dinesh Pillai, Gustavo Nino
BACKGROUND: Human Rhinovirus (HRV) has been identified as the most common cause of acute respiratory infections and hospitalizations in premature children. It is unclear if premature children are more susceptible to HRV due to their decreased pulmonary reserve or because they have enhanced lower airway reactivity to HRV. METHODS: We conducted a retrospective analysis of the clinical respiratory presentation of all PCR-confirmed HRV infections in full-term and premature children aged ≤3 years in our institution...
September 27, 2017: Pediatrics and Neonatology
Kei Ogasawara, Maki Sato, Koichi Hashimoto, Takashi Imamura, Hayato Go, Mitsuaki Hosoya
BACKGROUND: Glucocorticoids play an important role in endocrine control. The association of glucocorticoid receptor (GR) gene polymorphisms with altered sensitivity to glucocorticoid therapy has been reported in adults. However, there are few such reports in infants. The present study analyzed the prevalence of four GR polymorphisms in preterm infants born before 30 weeks of gestation and determined the associations between these polymorphisms and clinical outcomes in the infants. METHODS: Totally, 41 preterm infants born at two hospitals in Fukushima were retrospectively screened for the presence of four GR gene polymorphisms, using a TaqMan single-nucleotide polymorphism genotyping assay...
September 27, 2017: Pediatrics and Neonatology
Vasanthan Tanigasalam, Mamatha Gowda, Nishad Plakkal, B Adhisivam, B Vishnu Bhat
No abstract text is available yet for this article.
September 27, 2017: Pediatrics and Neonatology
Yan Li, Qiu-Fen Wei, Dan-Hua Meng, Xin-Nian Pan, Yan Mo, Li-Ping Yao, Lian-Fang Jing, Dan Zhao, Kai-Yan Shen, Jing Xu
BACKGROUND: In developing countries, infant survival rate and long-term outcomes of extremely preterm infants(EPIs) have significantly improved due to advances in perinatal care. The striking gap in the treatment outcome of EPIs between China and the other developed countries was a major concern. To assess treatment outcomes and associated factors among EPIs in Nanning, China. METHODS: This was a perspective study consisting of eligible cases with gestational age between 22 and 28 weeks and infants were followed to 18-24 months of age...
September 25, 2017: Pediatrics and Neonatology
Xia-Fang Chen, Jing Wu, Yi-Dan Zhang, Chen-Xing Zhang, Xu-Ting Chen, Jian-Hua Sun, Tong-Xin Chen
BACKGROUND: The uncontrolled inflammatory response following infection is closely related to the morbidity and mortality of neonates. Interleukin 6 (IL-6) plays an important role in the pathogenesis and prognosis of this process. To better elucidate the secretion of IL-6 following infection in neonates, we investigated the IL-6 level and mechanism of IL-6/TLR4 signaling pathways. METHODS: We compared the IL-6, procalcitonin (PCT), and CRP levels between septic neonates and toddlers...
September 21, 2017: Pediatrics and Neonatology
Syunsuke Nagara, Masanori Kouwaki, Takao Togawa, Tokio Sugiura, Mayumi Okada, Norihisa Koyama
BACKGROUND: Marked improvements have been achieved in the survival of extremely low birth weight infants, but survival rates and prognoses of extremely small infants with birth weights ≤500 g remain poor. The aim of this study was to clarify long-term outcomes for surviving infants with birth weights ≤500 g. METHODS: The study population comprised fetuses of gestational age ≥22 weeks, expected live- or stillbirth weight ≤500 g, and birth date between 2003 and 2012...
September 21, 2017: Pediatrics and Neonatology
Chun-Chih Peng, Jui-Hsing Chang, Hsiang-Yu Lin, Po-Jen Cheng, Bai-Horng Su
Chorioamnionitis is a common cause of preterm birth and may cause adverse neonatal outcomes, including neurodevelopmental sequelae. Chorioamnionitis has been marked to a heterogeneous setting of conditions characterized by infection or inflammation or both, followed by a great variety in clinical practice for mothers and their newborns. Recently, a descriptive term: "intrauterine inflammation or infection or both" abbreviated as "Triple I" has been proposed by a National Institute of Child Health and Human Development expert panel to replace the term chorioamnionitis...
September 19, 2017: Pediatrics and Neonatology
Hsin-Hsu Chou, Mei-Yung Chung, Xiao-Guang Zhou, Hung-Chih Lin
No abstract text is available yet for this article.
September 9, 2017: Pediatrics and Neonatology
Hideaki Yagasaki, Takako Toda, Keiichi Koizumi, Takeshi Sugiyama, Tetsuo Ohyama, Minako Hoshiai, Takaya Nakane, Kanji Sugita
No abstract text is available yet for this article.
September 6, 2017: Pediatrics and Neonatology
Chang-Yo Yang, Mei-Chin Yang, Shih-Ming Chu, Ming-Chou Chiang, Reyin Lien
BACKGROUND: There is a lack of evidence to guide step-wise weaning of positive pressure respiratory support for premature infants. This study sought to compare the efficacy of three weaning protocols we designed to facilitate weaning of very low birth weight (VLBW, less than 1500 g) preterm infants from nasal continuous positive airway pressure (NCPAP) support. METHODS: This was a prospective, randomized, controlled trial of VLBW preterm infants who received positive pressure ventilatory support in our neonatal intensive care unit (NICU) from April 2008 through March 2009...
September 6, 2017: Pediatrics and Neonatology
Ming-Dar Lee, Chun-Chen Lin, Brian Pin-Hsuan Chang, Pei-Yi Lin, Jeng-Daw Tsai
No abstract text is available yet for this article.
September 6, 2017: Pediatrics and Neonatology
Shio-Jean Lin
No abstract text is available yet for this article.
September 6, 2017: Pediatrics and Neonatology
Fu-Wen Liang, Hung-Chieh Chou, Shu-Ti Chiou, Li-Hua Chen, Mei-Hwan Wu, Hung-Chi Lue, Tung-Liang Chiang, Tsung-Hsueh Lu
BACKGROUND: A yearly increase in the proportion of very low birth weight (VLBW) live births has resulted in the slowdown of decreasing trends in crude infant mortality rates (IMRs). In this study, we examined the trends in birth weight-specific as well as birth weight-adjusted IMRs in Taiwan. METHODS: We linked three nationwide datasets, namely the National Birth Reporting Database, National Birth Certification Registry, and National Death Certification Registry databases, to calculate the IMRs according to the birth weight category...
September 4, 2017: Pediatrics and Neonatology
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