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Pediatrics and Neonatology

Chung-Lin Lee, Chen-Hao Lee, Chih-Kuang Chuang, Huei-Ching Chiu, Yen-Jiun Chen, Chao-Ling Chou, Peih-Shan Wu, Chih-Ping Chen, Hsiang-Yu Lin, Shuan-Pei Lin
BACKGROUND: Unexplained developmental delay or intellectual disability (DD/ID) has an estimated prevalence of about 3%-5% in the general population of Taiwan. Array comparative genomic hybridization (array-CGH) is a high-resolution tool that can detect about 50 Kb chromosome aberrations. A previous study has reported a detection rate of 10%-20% for this array.1 This study aimed to investigate and compare the diagnosis rate for DD/ID using array-CGH and conventional chromosome study in DD/ID patients in Taiwan...
November 27, 2018: Pediatrics and Neonatology
Jiyoung Chun, Sang Hoon Chun, Yea Seul Han, Tae-Jung Sung
BACKGROUND: Ureaplasma spp. is a known risk factor for bronchopulmonary dysplasia (BPD). However, little is known about the effect of different degrees of maternal Ureaplasma colonization and their adverse outcomes. Hence, the aim of this study was to determine the effects of different degrees of maternal Ureaplasma colonization on BPD. METHODS: A retrospective cohort study of preterm infants delivered at <32 weeks' gestational age (GA) was performed. The infants were divided according to maternal Ureaplasma status as follows: high-colonization (≥104  CCU/ml, UUH), low-colonization (<104  CCU/ml, UUL), and noncolonization (controls)...
November 27, 2018: Pediatrics and Neonatology
Caixia Yan, Binghong Zhang
BACKGROUND: To investigate the clinical values of serum melatonin and αII spectrin cleavage products (SBDPs) in assessing the severity of brain injury in preterm infants. METHODS: Sixty-four premature infants in total were selected and classified into the brain injury group (BI, n = 30) and the non-brain injury group (CON, n = 34) according to cranial imaging examination. The serum melatonin and SBDPs were detected by ELISA. All the preterm infants were received NBNA testing at 40 weeks of corrected gestational age...
November 25, 2018: Pediatrics and Neonatology
Min Sun Kim, Dae Sun Jo, Dae-Yeol Lee
BACKGROUND: The aim of this study was to evaluate the correlation between plasma glucose and HbA1c and the diagnostic accuracy of HbA1c as a screening tool to identify asymptomatic diabetes mellitus in children and adolescents with obesity or asymptomatic glucosuria. METHODS: A total of 190 subjects who underwent an oral glucose tolerance test (OGTT) to confirm diabetes were categorized into normal glucose tolerance (NGT; n = 117), impaired glucose tolerance (IGT; n = 33), and diabetes (DM; n = 40) according to the OGTT...
November 9, 2018: Pediatrics and Neonatology
Chin Yee Ho, Gwo-Tsann Chuang, Wei-Chou Lin, I-Jung Tsai
No abstract text is available yet for this article.
November 8, 2018: Pediatrics and Neonatology
Tülin Güngör, Özlem Arman Bilir, Vildan Koşan Çulha, Ali Güngör, Abdurrahman Kara, Fatih Mehmet Azık, Hüsniye Neşe Yaralı
OBJECTIVE: Immune thrombocytopenic purpura (ITP) is the most common cause of acquired thrombocytopenia children. The aim of this retrospective study is to describe presenting features and clinical characteristics of ITP and evaluate clinical course, treatment modalities, and complications and determine the effects of preceding infection history, age, gender, treatment modality, and admission platelet count on chronicity. METHOD: Two hundred and eleven patients who were diagnosed ITP and followed-up in Department of Pediatric Hematology, Ankara Children Hematology Oncology Education and Research Hospital between January 2008 and September 2012 were included...
November 3, 2018: Pediatrics and Neonatology
Po-Cheng Hung, Yu-Ching Chang, Meng-Ying Hsieh, Chieh-Tsai Wu
No abstract text is available yet for this article.
November 1, 2018: Pediatrics and Neonatology
Andrew J Degnan, William W Fox, Huayan Zhang, David Saul
No abstract text is available yet for this article.
November 1, 2018: Pediatrics and Neonatology
Yosuke Ono, Kentaro Tamura, Satomi Inomata, Takeshi Futatani, Shigeru Saito, Taketoshi Yoshida
No abstract text is available yet for this article.
October 31, 2018: Pediatrics and Neonatology
Itamar Nitzan, Shmuel Goldberg, Cathy Hammerman, Alona Bin-Nun, Ruben Bromiker
BACKGROUND: To assess changes in clinical condition and oxygenation in neonates after rewarming following moderate therapeutic hypothermia (MTH) for neonatal encephalopathy. METHODS: Retrospective study of 28 neonates receiving MTH in a tertiary neonatal intensive care unit in Israel. We compared pre-and 24 h post-rewarming arterial oxygen saturation (SaO2 ) as measured by the blood gases analyzer, pulse-oximetry saturation (SpO2 ), and cardio-respiratory condition...
October 31, 2018: Pediatrics and Neonatology
Shu-Sing Kong, Yun-Ju Chen, I-Chen Su, Jainn-Jim Lin, I-Jun Chou, Min-Liang Chou, Po-Cheng Hung, Meng-Ying Hsieh, Yi-Shan Wang, Cheng-Che Chou, Huei-Shyong Wang, Kuang-Lin Lin
BACKGROUND: Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an anti-neuronal antibody-mediated inflammatory brain disease that causes severe psychiatric and neurological deficits in previously healthy patients. The aims of this study were to demonstrate the clinical characteristics of patients diagnosed with anti-NMDA receptor encephalitis and to compare the different treatment strategies among these patients. METHODS: Patients presenting with newly acquired psychiatric and/or neurological deficits were studied retrospectively from 2009 to 2017...
October 31, 2018: Pediatrics and Neonatology
Hung-Chieh Chou
No abstract text is available yet for this article.
December 2018: Pediatrics and Neonatology
Il Ki Hong, Mi Hae Chung, Joong Hyun Bin, Kyung-Yil Lee, Jung Sue Kim, Chung Ho Kim, Jin-Soon Suh
BACKGROUND: Vesicoureteral reflux (VUR) is an important urologic anomaly that causes renal injury in children with febrile urinary tract infection (UTI). The present study aimed to evaluate the associations of abnormalities detected on technetium-99m-labeled dimercaptosuccinic acid (DMSA) scans, focusing on the association with VUR of the levels of relative decrease in kidney function and cortical defects after a first febrile UTI in children. METHODS: All 171 children underwent ultrasonography, DMSA scan and voiding cystourethrography (VCUG)...
December 2018: Pediatrics and Neonatology
Candice Fabre, Barthélémy Tosello, Estelle Pipon, Catherine Gire, Kathia Chaumoitre
BACKGROUND: Lenticulostriate vasculopathy (LSV) is a hyperechogenicity of the lenticulostriate branches of the basal ganglia and/or thalamus' middle cerebral arteries and is frequently seen in neonatology. Our study primarily describes the perinatal data and long-term follow-up of newborns with lenticulostriate vessel hyperechoic degeneration. Secondly, it describes the cerebral imaging data as a function of perinatal factors and neurodevelopmental follow-up of these newborns. METHODS: This retrospective study assesses the outcome of newborns with LSV hyperechogenicity on cerebral ultrasound (two grades)...
December 2018: Pediatrics and Neonatology
Sara Dal Bo, Francesca Currò, Alberto Ratta, Simona Straziuso, Federico Marchetti
No abstract text is available yet for this article.
October 4, 2018: Pediatrics and Neonatology
Wei-Tsun Kao, Yung-Hao Tseng, Yuh-Jyh Jong, Tai-Heng Chen
BACKGROUND: No previous studies have explored emergency medical care for children with chronic neuromuscular disorders (NMDs). We aimed to determine the major reasons for the emergency room (ER) readmission of pediatric patients with NMDs and suggest changes to the care plan to decrease readmissions. METHODS: Children with chronic NMDs (aged <18 years) who visited a medical center-based ER between January 2005 and January 2015 were included. The following data were extracted from the patient's ER records: presentations; demographic data, including sex and age; NMD diagnosis; triage classification; emergency examination; initial management and outcomes...
October 2, 2018: Pediatrics and Neonatology
Mei-Jy Jeng
No abstract text is available yet for this article.
October 2018: Pediatrics and Neonatology
Anca Chiriac, Cristian Podoleanu, Adrian Naznean, Simona Stolnicu
No abstract text is available yet for this article.
October 2018: Pediatrics and Neonatology
Tze Yee Diane Mok, Min-Hua Tseng, Ming-Chou Chiang, Ju-Li Lin, Shih Ming Chu, Jen-Fu Hsu, Reyin Lien
BACKGROUND: Renal replacement therapy (RRT) is becoming increasingly necessary for supporting critically ill neonates. Few studies have reported the use of RRT in the neonatal intensive care unit (NICU). Therefore, we performed a retrospective study to describe the use of RRT in our NICU and its associated efficacy, complications, and outcomes. METHODS: We identified patients requiring RRT between January 2009 and January 2017. Demographic data, mode of RRT, and associated factors were recorded...
October 2018: Pediatrics and Neonatology
Amir Bein, Smadar Eventov-Friedman, Dan Arbell, Betty Schwartz
BACKGROUND & AIMS: Necrotizing Enterocolitis (NEC) is a severe inflammatory disorder of the intestine endangering the health and survival of preterm infants. It is well established that the gut barrier is severely damaged in NEC patients, nonetheless an in depth investigation of modifications at the transcriptional and translational levels of tight junction genes and proteins during NEC are still missing. The aim of this study was to investigate changes in the expression of tight junctions and other associated proteins during NEC and determine their correlation to the disease severity...
October 2018: Pediatrics and Neonatology
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