journal
MENU ▼
Read by QxMD icon Read
search

Materials Science & Engineering. C, Materials for Biological Applications

journal
https://www.readbyqxmd.com/read/28254338/controlled-co-release-of-doxorubicin-and-reactive-oxygen-species-for-synergistic-therapy-by-nir-remote-triggered-nanoimpellers
#1
Beibei Hou, Weitao Yang, Chunhong Dong, Bin Zheng, Ying Zhang, Jing Wu, Hanjie Wang, Jin Chang
How to encapsulate and transport the payload of multiple therapeutic compounds avoiding premature leakage, and simultaneously co-release them rapidly at specific lesions still remains the major concern in clinic. Herein, we designed the UCN@mSiO2-(Azo+RB) (azobenzene groups and Rose Bengal) nanoimpellers, which used the multicolor-emission capability of the core-shell upconverting nanoparticles (UCNs) at a single excitation wavelength to co-release anticarcinogen doxorubicin (Dox) and reactive oxygen species (ROS) for combined chemotherapy and photodynamic therapy (PDT)...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254337/electrospun-water-stable-zein-ethyl-cellulose-composite-nanofiber-and-its-drug-release-properties
#2
Hangyi Lu, Qingqing Wang, Guohui Li, Yuyu Qiu, Qufu Wei
A simple and cost-effective way to prepare water-stable zein-based nanofibers for potential drug delivery was presented in this article. Corn protein zein was co-electrospun with hydrophobic ethyl cellulose. Indomethacin, as a model drug, was incorporated in situ into the composite nanofibers. Scanning electron microscopy and element mapping revealed the morphologies of drug-loaded nanofibers and drug distribution, respectively. Fourier transform infrared spectra confirmed the physical blending among the components...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254336/nanofibrous-matrixes-with-biologically-active-hydroxybenzophenazine-pyrazolone-compound-for-cancer-theranostics
#3
Subramani Kandhasamy, Giriprasath Ramanathan, Thangavelu Muthukumar, SitaLakshmi Thyagarajan, Narayanan Umamaheshwari, V P Santhanakrishnan, Uma Tiruchirapalli Sivagnanam, Paramasivan Thirumalai Perumal
The nanomaterial with the novel biologically active compounds has been actively investigated for application in cancer research. Substantial use of nanofibrous scaffold for cancer research with potentially bioactive compounds through electrospinning has not been fully explored. Here, we describe the series of fabrication of nanofibrous scaffold loaded with novel potential biologically active hydroxybenzo[a]phenazine pyrazol-5(4H)-one derivatives were designed, synthesized by a simple one-pot, two step four component condensation based on Michael type addition reaction of lawsone, benzene-1,2-diamine, aromatic aldehydes and 3-methyl-1-phenyl-1H-pyrazol-5(4H)-one as the substrates...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254335/magnetism-assisted-modification-of-screen-printed-electrode-with-magnetic-multi-walled-carbon-nanotubes-for-electrochemical-determination-of-dopamine
#4
Yong-Mei Zhang, Pei-Li Xu, Qiong Zeng, Yi-Ming Liu, Xun Liao, Mei-Fang Hou
A simple and sensitive dopamine (DA) electrochemical sensor was fabricated based on magnetism-assisted modification of screen printed electrode (SPE) with magnetic multi-walled carbon nanotubes (mMWCNTs). The mMWCNTs modified electrodes (mMWCNTs/SPE) combines the advantages of SPE and the simultaneous contribution of magnetic nanoparticles (MNPs) and MWCNTs, increasing sensitivity and selectivity of DA detection. The linearity was found between 5μM to 180μM, with the limit of detection (LOD) of 0.43μM. In the mean time, this modified electrode exhibited excellent selectivity for DA detection with almost no interference from ascorbic acid (AA), which co-exists with DA in many bio-samples and causes common interference...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254334/selenium-nanoparticles-synthesized-in-aqueous-extract-of-allium-sativum-perturbs-the-structural-integrity-of-calf-thymus-dna-through-intercalation-and-groove-binding
#5
Preedia Babu Ezhuthupurakkal, Lokeswara Rao Polaki, Arumugam Suyavaran, Ariraman Subastri, Venugopal Sujatha, Chinnasamy Thirunavukkarasu
Biomedical application of selenium nanoparticles (SeNPs) demands the eco-friendly composite for synthesis of SeNPs. The present study reports an aqueous extract of Allium sativum (AqEAS) plug-up the current need. Modern spectroscopic, microscopic and gravimetric techniques were employed to characterize the synthesized nanoparticles. Characterization studies revealed the formation of crystalline spherical shaped SeNPs. FTIR spectrum brings out the presence of different functional groups in AqEAS, which influence the SeNPs formation and stabilization...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254333/improvement-of-the-mechanical-properties-and-corrosion-resistance-of-biodegradable-%C3%AE-ca3-po4-2-mg-zn-composites-prepared-by-powder-metallurgy-the-adding-%C3%AE-ca3-po4-2-hot-extrusion-and-aging-treatment
#6
Yang Yan, Yijun Kang, Ding Li, Kun Yu, Tao Xiao, Youwen Deng, Han Dai, Yilong Dai, Hanqing Xiong, Hongjie Fang
In this study, 10%β-Ca3(PO4)2/Mg-6%Zn (wt.%) composites with Mg-6%Zn alloy as control were prepared by powder metallurgy. After hot extrusion, the as-extruded composites were aged for 72h at 150°C. The effects of the adding β-Ca3(PO4)2, hot extrusion and aging treatment on their microstructure, mechanical properties and corrosion resistance were investigated. The XRD results identified α-Mg, MgZn phase and β-Ca3(PO4)2 phase in these composites. After hot extrusion, grains were significantly refined, and the larger-sized β-Ca3(PO4)2 particles and coarse MgZn phases were broken into linear-distributed β-Ca3(PO4)2 and MgZn phases along the extrusion direction...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254332/anti-bacterial-activity-of-graphene-oxide-as-a-new-weapon-nanomaterial-to-combat-multidrug-resistance-bacteria
#7
REVIEW
Mohammadreza Yousefi, Mehdi Dadashpour, Maryam Hejazi, Mohammad Hasanzadeh, Behzad Behnam, Miguel de la Guardia, Nasrin Shadjou, Ahad Mokhtarzadeh
Antibiotic resistance in microbial pathogens has become a serious health problem in the world. The increasing spread of hospital acquired infections especially in immunocompromised and cancer patients caused by multidrug-resistant (MDR) microbial pathogens is restricting the choices for impressive antibiotic therapy. So many efforts have been made to develop new compounds with antimicrobial activity. In recent years, nanoparticles, particularly graphene oxide (GO) nanoparticles have found many applications in various fields, including antibacterial action, pathogens bio detection, cancer therapy, and drug and gene delivery...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254331/flexible-magnetic-polyurethane-fe2o3-nanoparticles-as-organic-inorganic-nanocomposites-for-biomedical-applications-properties-and-cell-behavior
#8
Mohsen Shahrousvand, Monireh Sadat Hoseinian, Marzieh Ghollasi, Ali Karbalaeimahdi, Ali Salimi, Fatemeh Ahmadi Tabar
Nowadays, the discovery of cell behaviors and their responses in communication with the stem cell niches and/or microenvironments are one of the major topics in tissue engineering and regenerative medicine. In this study, incorporated organic-inorganic polyurethane (PU) nanocomposites were prepared for better understanding of cell signaling and the effect of magnetite nanoparticles on cell proliferation and cell responses. The properties of PU-IONs were evaluated by fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), atomic-force microscopy (AFM), differential scanning calorimetry (DSC), X-ray diffraction (XRD) and electrochemical impedance spectroscopy (EIS)...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254330/selective-colorimetric-and-fluorescence-turn-on-sensor-for-ag-and-in-situ-sensing-of-cn-off-on-off-via-displacement-approach
#9
Nirma Maurya, Shubhrajyotsna Bhardwaj, Ashok Kumar Singh
In this contemporary work we designed and synthesized a simple tetra dentate Schiff base, which displays colorimetric and fluorescence "turn on" sensing behavior towards Ag(+) in aqueous DMF (50%) solution. Benesi Hildebrand-plot reveals 1:2 binding mode between probe and Ag(+) with limit of detection down to 1.12μM. Cyclic voltammograms exhibits high anodic shift with Ag(+) due to the charge transfer from ligand to metal ion. The binding mode was proved by NMR titrations, FE-SEM elemental analysis & advance DFT calculation...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254329/how-do-wettability-zeta-potential-and-hydroxylation-degree-affect-the-biological-response-of-biomaterials
#10
S Spriano, V Sarath Chandra, A Cochis, F Uberti, L Rimondini, E Bertone, A Vitale, C Scolaro, M Ferrari, F Cirisano, G Gautier di Confiengo, S Ferraris
It is well known that composition, electric charge, wettability and roughness of implant surfaces have great influence on their interaction with the biological fluids and tissues, but systematic studies of different materials in the same experimental conditions are still lacking in the scientific literature. The aim of this research is to investigate the correlations between some surface characteristics (wettability, zeta potential and hydroxylation degree) and the biological response (protein adsorption, blood wettability, cell and bacterial adhesion) to some model biomaterials...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254328/antibacterial-activity-of-microstructured-sacrificial-anode-thin-films-by-combination-of-silver-with-platinum-group-elements-platinum-palladium-iridium
#11
LETTER
Manfred Köller, Petri Bellova, Siyamak Memar Javid, Yahya Motemani, Chinmay Khare, Christina Sengstock, Kristina Tschulik, Thomas A Schildhauer, Alfred Ludwig
Five different Ag dots arrays (16 to 400dots/mm(2)) were fabricated on a continuous platinum, palladium, or iridium thin film and for comparison also on titanium film by sputter deposition and photolithographic patterning. To analyze the antibacterial activity of these microstructured films Staphylococcus aureus (S. aureus) were placed onto the array surfaces and cultivated overnight. To analyze the viability of planktonic as well as surface adherent bacteria, the applied bacterial fluid was subsequently aspirated, plated on blood agar plates and adherent bacteria were detected by fluorescence microscopy...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254327/addition-of-mgo-nanoparticles-and-plasma-surface-treatment-of-three-dimensional-printed-polycaprolactone-hydroxyapatite-scaffolds-for-improving-bone-regeneration
#12
Hee-Sang Roh, Chang-Min Lee, Young-Hyoun Hwang, Min-Suk Kook, Seong-Won Yang, Donghun Lee, Byung-Hoon Kim
Magnesium (Mg) plays an important role in the body in mediating cell-extracellular matrix interactions and controlling bone apatite structure and density. Hydroxyapatite (HAp) has been used for osteoconductive bone replacement because of its good compressive strength and biocompatibility. The object of this study is to investigate the effects of adding Magnesium oxide (MgO) nanoparticles to polycaprolactone (PCL)/HAp composites and treating PCL/HAp/MgO scaffolds with oxygen and nitrogen plasma. The 3D PCL/HAp/MgO scaffolds were fabricated using a 3D bioextruder...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254326/direct-electrochemistry-and-electrocatalysis-of-lobetyolin-via-magnetic-functionalized-reduced-graphene-oxide-film-fabricated-electrochemical-sensor
#13
Bolu Sun, Xiaodan Gou, Ruibin Bai, Ahmed Attia Ahmed Abdelmoaty, Yuling Ma, Xiaoping Zheng, Fangdi Hu
A novel lobetyolin electrochemical sensor based on a magnetic functionalized reduced graphene oxide/Nafion nanohybrid film has been introduced in this work. The magnetic functionalized reduced graphene oxide was characterized by fourier transform infrared spectroscopy, atomic force microscope, X-ray diffraction, transmission electron microscopy and thermogravimetric analysis. The scanning electron microscopy characterized the morphology and microstructure of the prepared sensors, and the electrochemical effective surface areas of the prepared sensors were also calculated by chronocoulometry method...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254325/vacuum-arc-plasma-deposition-of-thin-titanium-dioxide-films-on-silicone-elastomer-as-a-functional-coating-for-medical-applications
#14
Cécile Boudot, Marvin Kühn, Marina Kühn-Kauffeldt, Jochen Schein
Silicone elastomer is a promising material for medical applications and is widely used for implants with blood and tissue contact. However, its strong hydrophobicity limits adhesion of tissue cells to silicone surfaces, which can impair the healing process. To improve the biological properties of silicone, a triggerless pulsed vacuum cathodic arc plasma deposition technique was applied to deposit titanium dioxide (TiO2) films onto the surface. Scanning electron microscopy, atomic force microscopy, X-ray photoelectron spectroscopy, Raman spectroscopy and contact angle measurements were used for coating characterization...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254324/modification-of-ti6al4v-implant-surfaces-by-biocompatible-tio2-pcl-hybrid-layers-prepared-via-sol-gel-dip-coating-structural-characterization-mechanical-and-corrosion-behavior
#15
Michelina Catauro, Flavia Bollino, Roberto Giovanardi, Paolo Veronesi
Surface modification of metallic implants is a promising strategy to improve tissue tolerance, osseointegration and corrosion resistance of them. In the present work, bioactive and biocompatible organic-inorganic hybrid coatings were prepared using a sol-gel dip coating route. They consist of an inorganic TiO2 matrix in which different percentages of poly(ε-caprolactone) (PCL), a biodegradable and biocompatible polymer, were incorporated. The coatings were used to modify the surface of Ti6Al4V substrates in order to improve their wear and corrosion resistance...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254323/on-spray-drying-of-oxidized-corn-starch-cross-linked-gelatin-microcapsules-for-drug-release
#16
Xugang Dang, Mao Yang, Zhihua Shan, Shahnaz Mansouri, Bee K May, Xiaodong Chen, Hui Chen, Meng Wai Woo
Spray-dried gelatin/oxidized corn starch (G/OCS) microcapsules were produced for drug release application. The prepared microcapsules were characterized through a scanning electron microscope (SEM) picture and thermogravimetric analysis (TGA). The swelling characteristics of the G/OCS microcapsules and release properties of vitamin C were then investigated. The results from structural analysis indicated that the presence of miscibility and compatibility between oxidized corn starch and gelatin, and exhibits high thermal stability up to 326°C...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254322/regenerated-cellulose-micro-nano-fiber-matrices-for-transdermal-drug-release
#17
Yue Liu, Andrew Nguyen, Alicia Allen, Janet Zoldan, Yuxiang Huang, Jonathan Y Chen
In this work, biobased fibrous membranes with micro- and nano-fibers are fabricated for use as drug delivery carries because of their biocompatibility, eco-friendly approach, and potential for scale-up. The cellulose micro-/nano-fiber (CMF) matrices were prepared by electrospinning of pulp in an ionic liquid, 1-butyl-3-methylimidazolium chloride. A model drug, ibuprofen (IBU), was loaded on the CMF matrices by a simple immersing method. The amount of IBU loading was about 6% based on the weight of cellulose membrane...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254321/characterization-and-in-vitro-evaluation-of-biphasic-%C3%AE-tricalcium-phosphate-%C3%AE-tricalcium-phosphate-cement
#18
Takaaki Arahira, Michito Maruta, Shigeki Matsuya
Biphasic calcium phosphate consisting of hydroxyapatite (HA) and β-tricalcium phosphate(β-TCP) is an excellent bone substitute with controllable bioresorbability. Fabrication of biphasic calcium phosphate with self-setting ability is expected to enhance its potential application as bone substitute. In this study, mixtures of α-TCP and β-TCP with various compositions were prepared through α-β phase transition of α-TCP powder at 1000°C for various periods. These powders were mixed with 0.25M Na2HPO4 at a P/L ratio of 2, and then hardened at 37°C at 100% RH for up to 24h...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254320/the-control-of-beads-diameter-of-bead-on-string-electrospun-nanofibers-and-the-corresponding-release-behaviors-of-embedded-drugs
#19
Tingxiao Li, Xin Ding, Lingling Tian, Jiyong Hu, Xudong Yang, Seeram Ramakrishna
Bead-on-string nanofibers, with appropriate control of the beads diameter, are potential fibrous structures for efficient encapsulation of particle drugs in micron scales and could achieve controlled drug release for tissue engineering applications. In this study, the beads diameter of electrospun bead-on-string nanofibers was controlled by adjusting the concentration of spinning polymer, poly (lactic-co-glycolic acid) (PLGA), and the solvent ratio of chloroform to acetone. The images of the scanning electron microscopy (SEM) suggested that bead-on-string nanofibers could be successfully obtained only with a certain range of PLGA solution concentration...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28254319/evaluation-of-bioactive-glass-incorporated-poly-caprolactone-poly-vinyl-alcohol-matrix-and-the-effect-of-bmp-2-modification
#20
Khamsone Keothongkham, Narattaphol Charoenphandhu, Jirawan Thongbunchoo, Panan Suntornsaratoon, Nateetip Krishnamra, I-Ming Tang, Weeraphat Pon-On
Composite materials having mechanical and biological properties similar to those of human bones are needed for bone regeneration and repair. In the present study, composites were made by incorporating bioactive glass (BG) into polycaprolactone (PCL)-polyvinyl alcohol (PVA) (PCLPVA) matrix. Composites with different BG contents of 10, 25 and 50wt% were fabricated by an in-situ blending method. Physicochemical properties measurements found that the composite with 50wt% BG in the PCLPVA organic matrix exhibited the best mechanical properties (compressive strength and compressive young's modulus up to 32...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
journal
journal
42150
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"