journal
MENU ▼
Read by QxMD icon Read
search

Materials Science & Engineering. C, Materials for Biological Applications

journal
https://www.readbyqxmd.com/read/29208293/mesoporous-silica-based-bioactive-glasses-for-antibiotic-free-antibacterial-applications
#1
REVIEW
Seray Kaya, Mark Cresswell, Aldo R Boccaccini
Bioactive glasses (BGs) are being used in several biomedical applications, one of them being as antibacterial materials. BGs can be produced via melt-quenching technique or sol-gel method. Bactericidal silver-doped sol-gel derived mesoporous silica-based bioactive glasses were reported for the first time in 2000, having the composition 76SiO2-19CaO-2P2O5-3Ag2O (wt%) and a mean pore diameter of 28nm. This review paper discusses studies carried out exploring the potential antibacterial applications of drug-free mesoporous silica-based BGs...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208292/hydroxyapatite-mesoporous-silica-coated-gold-nanorods-with-improved-degradability-as-a-multi-responsive-drug-delivery-platform
#2
Zhixuan Song, Yang Liu, Jun Shi, Teng Ma, Zheng Zhang, He Ma, Shaokui Cao
In this study, gold nanorods/mesoporous silica/hydroxyapatite (Au/SiO2/HAP) hybrid nanoparticles with AuNR core and SiO2/HAP hybrid inorganic shell for multi-responsive drug delivery had been prepared. The morphology and structure of the nanoparticles were characterized by TEM, XPS, XRD, FT-IR and N2 adsorption-desorption isotherms. The degradation of the hybrid nanoparticles could be significantly improved by the dissolution of HAP from the hybrid skeleton in acid environment. In vitro drug release results indicated that Au/SiO2/HAP nanoparticles exhibited high drug loading efficiency, excellent near-infrared (NIR)- and pH-responsive drug release properties...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208291/optimization-of-the-composition-and-dosage-of-pegylated-polyethylenimine-entrapped-gold-nanoparticles-for-blood-pool-tumor-and-lymph-node-ct-imaging
#3
Yue Wang, Zhijuan Xiong, Yao He, Benqing Zhou, Jiao Qu, Mingwu Shen, Xiangyang Shi, Jindong Xia
Gold nanoparticles (Au NPs) with a high X-ray attenuation coefficient have a good potential in CT imaging applications. Here, we report the design and synthesis of Au NPs entrapped within polyethylene glycol (PEG)-modified branched polyethyleneimine (PEI) with varying the initial Au salt/PEI molar ratios and with the remaining PEI surface amines being acetylated for blood pool, lung tumor and lymph node CT imaging. The formed unacetylated and acetylated PEGylated PEI-entrapped Au NPs (Au PENPs) were characterized via different methods...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208290/synthesis-spectroscopic-thermal-and-molecular-modeling-studies-of-zn2-cd2-and-uo22-complexes-of-schiff-bases-containing-triazole-moiety-antimicrobial-anticancer-antioxidant-and-dna-binding-studies
#4
Mohamed Gaber, Hoda A El-Ghamry, Shaimaa K Fathalla, Mohammed A Mansour
A novel series of Zn2+, Cd2+ and UO22+ complexes of ligands namely 1-[(5-mercapto-1H-1,2,4-triazole-3-ylimino) methyl]naphthalene-2-ol (HL1) and [(1H-1,2,4-triazole-3-ylimino) methyl] naphthalene-2-ol (HL2) have been prepared and characterized by different analytical and spectral techniques. The stoichiometry, stereochemistry, conductivity measurements and mode of bonding of the complexes have been elucidated. Accurate comparison of the IR spectra of the ligands with their metal chelates proved the involvement of nitrogen atoms of the azomethine group and/or triazole ring in chelation in addition to the deprotonated hydroxyl oxygen...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208289/elastic-polyurethane-bearing-pendant-tgf-%C3%AE-1-affinity-peptide-for-potential-tissue-engineering-applications
#5
Gang Wu, Meng Xiao, Jiangwei Xiao, Lin Guo, Yu Ke, Hong Li, Liming Fang, Chunlin Deng, Hua Liao
No abstract text is available yet for this article.
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208288/rhombicuboctahedron-unit-cell-based-scaffolds-for-bone-regeneration-geometry-optimization-with-a-mechanobiology-driven-algorithm
#6
Antonio Boccaccio, Michele Fiorentino, Antonio E Uva, Luca N Laghetti, Giuseppe Monno
In a context more and more oriented towards customized medical solutions, we propose a mechanobiology-driven algorithm to determine the optimal geometry of scaffolds for bone regeneration that is the most suited to specific boundary and loading conditions. In spite of the huge number of articles investigating different unit cells for porous biomaterials, no studies are reported in the literature that optimize the geometric parameters of such unit cells based on mechanobiological criteria. Parametric finite element models of scaffolds with rhombicuboctahedron unit cell were developed and incorporated into an optimization algorithm that combines them with a computational mechanobiological model...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208287/development-of-temozolomide-coated-nano-zinc-oxide-for-reversing-the-resistance-of-malignant-glioma-stem-cells
#7
Meiguang Zheng, Shengwen Wang, Zhenghao Liu, Lin Xie, Yuefei Deng
Recently most of the researchers have turned their interest towards plant mediated synthesis of metal nanoparticles to avoid several environmental toxicants. In this manuscript, we have discussed the ecofriendly syntheses of zinc oxide nanoparticles (ZnO NPs) were achieved using Glycyrrhiza glabra (G. glabra) seed aqueous extract. The green synthesized ZnO NPs were characterized using analytical techniques like XRD, TEM, particle size histogram and Zeta potential. From the results, it was found that the green synthesized ZnO NPs were around 35nm in size with irregular spherical shape...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208286/one-pot-biocatalytic-synthesis-of-a-biodegradable-electroactive-macromonomer-based-on-3-4-ethylenedioxytiophene-and-poly-l-lactic-acid
#8
Aruã C da Silva, Tatiana Augusto, Leandro H Andrade, Susana I Córdoba de Torresi
A novel electroactive macromonomer based on poly(l-lactic acid) (PLLA) with (3,4-ethylenedioxythiophene) (EDOT) functional end groups, was prepared by a traditional approach of organometallic polymerization with stannous octanoate [Sn(oct2)] and enzymatic polymerization using immobilized Candida antarctica Lipase B (CAL-B) and Amano lipase Pseudomonas cepacia(PS-IM), as catalysts. In the synthetic strategy, (2,3-dihydrothieno[3,4-b] dioxin-2-yl)methanol (EDOT-OH) was used to initiate the ring opening polymerization of lactide to yield PLLA with EDOT end group...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208285/hybrid-nanofibers-based-on-poly-caprolactone-gelatin-hydroxyapatite-nanoparticles-loaded-doxycycline-effective-anti-tumoral-and-antibacterial-activity
#9
Ricardo Ramírez-Agudelo, Karina Scheuermann, Alfonso Gala-García, Ana Paula F Monteiro, Ana Delia Pinzón-García, Maria E Cortés, Rubén D Sinisterra
Cancer is one of the leading causes of morbidity and mortality Worldwide, 19.3 million new cancer cases are expected to be identified in 2025. Among the therapeutic arsenal to cancer control one could find the Doxycycline and the nano hydroxyapatite. The Doxycycline (Dox) not only shown antibiotic effect but also exhibits a wide range of pleiotropic therapeutic properties as the control of the invasive and metastatic cancer cells characteristics. The purpose of the present study was to evaluate both cytotoxicity in vitro and antibacterial activity of electrospun Dox-loaded hybrid nanofibrous scaffolds composed by hydroxyapatite nanoparticles (nHA), poly-ε-caprolactone (PCL) and gelatin (Gel) polymers...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208284/corrigendum-to-liposome-based-drug-co-delivery-systems-in-cancer-cells-mater-sci-eng-c-71-2017-1327-1341
#10
Sepideh Zununi Vahed, Roya Salehi, Soodabeh Davaran, Simin Sharifi
No abstract text is available yet for this article.
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208283/a-review-of-recent-progress-in-drug-and-protein-encapsulation-approaches-applications-and-challenges
#11
REVIEW
Chen Ye, Hong Chi
Many drugs and proteins formulated for treatment of various diseases are not fully utilised due to environmentally problems such as degradation by enzymes or it being hydrophobic. To counter this problem, the drug and protein of interest are encapsulated by synthetic polymers where they are protected from the environment. This allows the molecule to reach its target safely and maximise its function. In this paper, we will discuss about the different techniques of encapsulation that includes emulsion evaporation, self-emulsifying drug delivery system and supercritical fluid...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208282/polyester-micelles-for-drug-delivery-and-cancer-theranostics-current-achievements-progresses-and-future-perspectives
#12
REVIEW
Yu Yi, Gan Lin, Shaoyi Chen, Jing Liu, Huaping Zhang, Peng Mi
The development of tumor-targeting nanocarriers is critical important for effective treatment. The synthetic polyesters have demonstrated high potential for developing nanocarriers for cancer theranostics. Especially, the biocompatible and biodegradable polyester micelles have held great promise for cancer therapy and diagnosis, while some candidates have been translated into clinical applications or under clinical trial. In this review, we have provided the state-of-the-art of polyester micelles for drug delivery and cancer theranostics...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208281/overcoming-stc2-mediated-drug-resistance-through-drug-and-gene-co-delivery-by-phb-pdmaema-cationic-polyester-in-liver-cancer-cells
#13
Hongwei Cheng, Zhixian Wu, Caisheng Wu, Xiaoyuan Wang, Sing Shy Liow, Zibiao Li, Yun-Long Wu
Stanniocalcin 2 (STC2) overexpression in hepatocellular carcinoma (HCC) could lead to poor prognosis, which might be due to its induced P-glycoprotein and Bcl-2 protein expression level increase. P-glycoprotein or membrane pump induced drug efflux and altered prosurvival Bcl-2 expression are key mechanisms for drug resistance leading to failure of chemotherapy in HCC. However, current strategy to overcome both P-glycoprotein and Bcl-2 protein induced drug resistance was rarely reported. In this work, we utilized an amphiphilic poly[(R)-3-hydroxybutyrate] (PHB)-b-poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) cationic polyester to encapsulate chemotherapeutic paclitaxel (PTX) in hydrophobic PHB domain and Bcl-2 convertor Nur77/ΔDBD gene (Nur77 without DNA binding domain for mitochondria localization) by formation of polyplex due to cationic PDMAEMA segment, to effectively inhibit the drug resistant HepG2/STC2 and SMCC7721/STC2 liver cancer cell growth...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208280/formulation-and-biological-actions-of-nano-bioglass-ceramic-particles-doped-with-calcarea-phosphorica-for-bone-tissue-engineering
#14
S Dinesh Kumar, K Mohamed Abudhahir, N Selvamurugan, S Vimalraj, R Murugesan, N Srinivasan, A Moorthi
The improvisation of the treatment procedures for treating the various kind of bone defects such as, bone or dental trauma and for diseases such as osteoporosis, osteomyelitis etc., need the suitable and promising biomaterials with resemblance of bone components. Bioactive glass ceramic (BGC) has recently acquired great attention as the most promising biomaterials; hence it has been widely applied as a filler material for bone tissue regeneration. Because it elicts specific biological responses after implantation in addition more potential in formation of strong interface with both hard and soft tissues by dissolution of calcium and phosphate ions...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208279/collagen-alginate-as-bioink-for-three-dimensional-3d-cell-printing-based-cartilage-tissue-engineering
#15
Xingchen Yang, Zhenhui Lu, Huayu Wu, Wei Li, Li Zheng, Jinmin Zhao
Articular cartilage repair is still a huge challenge for researchers and clinicians. 3D bioprinting could be an innovative technology for cartilage tissue engineering. In this study, we used collagen type I (COL) or agarose (AG) mixed with sodium alginate (SA) to serve as 3D bioprinting bioinks and incorporated chondrocytes to construct in vitro 3D printed cartilage tissue. Swelling ratio, mechanical properties, scanning electron microscopy (SEM), cell viability and cytoskeleton, biochemistry analysis and quantitative real-time polymerase chain reaction (qRT-PCR) were performed to investigate the function of different bioinks in 3D printing cartilage tissue engineering applications...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208278/mixed-ligand-copper-ii-complex-of-quercetin-regulate-osteogenesis-and-angiogenesis
#16
Selvaraj Vimalraj, Subramaniyam Rajalakshmi, Desingh Raj Preeth, Sivasubramanian Vinoth Kumar, Thirumalai Deepak, Venkatraman Gopinath, Kadarkarai Murugan, Suvro Chatterjee
Copper(II) complex of quercetin Cu+Q, mixed ligand complexes, quercetin-Cu(II)-phenanthroline [Cu+Q(PHt)] and quercetin-Cu(II)-neocuproine [Cu+Q(Neo)] have been synthesized and characterized. From the FT-IR spectroscopic studies, it was evident that C-ring of quercetin is involved in the metal chelation in all the three copper complexes. C-ring chelation was further proven by UV-Visible spectra and the presence of Cu(II) from EPR spectroscopic investigations. These complexes were found to have osteogenic and angiogenic properties, observed through in vitro osteoblast differentiation and chick embryo angiogenesis assay...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208277/preliminary-investigation-of-the-effect-of-doping-of-copper-oxide-in-cao-sio2-p2o5-mgo-bioactive-composition-for-bone-repair-applications
#17
Pardeep Kaur, K J Singh, Arun Kumar Yadav, Henna Sood, Sumanpreet Kaur, Ramandeep Kaur, Daljit Singh Arora, Sukhraj Kaur
A diopside based bioactive system with a nominal composition of xCuO-(45.55-x)CaO-29.44 SiO2-10.28P2O5-14.73 MgO (x=0,1,3 and 5mol%) has been prepared by sol gel technique in the laboratory. X-ray Diffraction, Fourier Transform Infra-Red and Raman Spectroscopy, Field Emission Scanning Electron Microscopy along with Energy Dispersive X-ray Analysis and pH studies have been undertaken on the prepared samples before and after dipping the samples in simulated body fluid. It has been observed that hydroxyapatite layer starts to form with in 24h during immersion in simulated body fluid...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208276/development-of-novel-ph-sensitive-thiolated-chitosan-pmla-nanoparticles-for-amoxicillin-delivery-to-treat-helicobacter-pylori
#18
Muhammad Arif, Quan-Jiang Dong, Mazhar Ali Raja, Shah Zeenat, Zhe Chi, Chen-Guang Liu
The cysteine conjugated chitosan/PMLA multifunctional nanoparticles were synthesized as targeted Nano-drug delivery system to eradicate Helicobacter pylori. Helicobacter pylori specifically express urea transport protein on its membrane to carrying urea to the cytoplasm urease to supply ammonia that protects bacteria in the acid environment of the stomach. The clinical suitability of topical antimicrobial agents is required to get rid of Helicobacter pylori inside the inflamed basal region. In this work, cysteine conjugated chitosan derivative, Cys-CS for their mucoadhesive and anticoagulant properties was designed and synthesized, for the preparation of multifunctional nanoparticles...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208275/synergetically-understanding-the-interaction-between-nano-microspheres-and-peptide-for-controllable-drug-loading-via-experimental-and-theoretical-approaches
#19
Chunbao Du, Xiaoling Hu, Yuan Cheng, Junfeng Gao, Yong-Wei Zhang, Kehe Su, Zhijian Li, Nan Zhang, Ninghui Chang, Kaiyang Zeng
In this paper we systematically investigate the loading capacity of raspberry-like nano/microspheres with highly cross-linked structure for the peptide, immunostimulating hexapeptide from human (IHH), by integrating both experimental and simulation efforts. The experimental results indicate that the loading capacities of raspberry-like nano/microspheres with different functionalized chains vary drastically. To provide theoretical insights into the observed phenomenon, the typical raspberry-like nano/microspheres were simplified as effective functionalized groups, thereby the interactions between them and IHH were accurately calculated by ab initio method...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29208274/hemostatic-porous-sponges-of-cross-linked-hyaluronic-acid-cationized-dextran-by-one-self-foaming-process
#20
Jia-Ying Liu, Yang Li, Yang Hu, Gang Cheng, Enyi Ye, Chuanan Shen, Fu-Jian Xu
Effective hemostatic materials are very important for treating trauma cases. Natural polysaccharides have been particularly appealing in the development of new hemostatic materials due to their unique functions in human bodies. In this work, different polysaccharide-based hemostatic porous sponges (SHDP or SHDQ) of cross-linked hyaluronic acid (HA)/cationized dextran were readily prepared by the self-foaming process of HA and poly((2-dimethyl amino)-ethyl methacrylate)-grafted dextran (Dex-PDM) or partially-quaternized Dex-PDM in the presence of sodium trimetaphosphate crosslinkers...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
journal
journal
42150
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"