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Materials Science & Engineering. C, Materials for Biological Applications

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https://www.readbyqxmd.com/read/30184829/electrospun-three-dimensional-aligned-nanofibrous-scaffolds-for-tissue-engineering
#1
REVIEW
Guorui Jin, Rongyan He, Baoyong Sha, Wenfang Li, Huaibin Qing, Rui Teng, Feng Xu
Engineered tissue constructs rely on biomaterials as support structures for tissue repair and regeneration. Among these biomaterials, polyester biomaterials have been widely used for scaffold construction because of their merits such as ease in synthesis, degradable properties, and elastomeric characteristics. To mimic the aligned structures of native extracellular matrix (ECM) in tissues such as nerve, heart and tendon, various polyester materials have been fabricated into aligned fibrous scaffolds with fibers ranging from several nanometers to several micrometers in diameter by electrospinning in a simple and reproducible manner...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184828/polyester-based-nanoparticles-for-nucleic-acid-delivery
#2
REVIEW
Jing Zhao, Guojun Weng, Jianjun Li, Jian Zhu, Junwu Zhao
Gene therapy is promising for the treatment of inherited diseases and complex diseases such as chronic infections and cancer. The advancement in science and technology has extended the scope of gene therapy from gene transfer to the delivery of a variety of nucleic acids such as mRNA, antisense oligonucleotides (ASOs), siRNA and miRNA. Nanoparticle delivery systems can efficiently protect the nucleic acids from enzymatic degradation and immune recognition, facilitate intracellular transportation and assist the nucleic acid in escaping from renal and hepatic clearance, thus achieve sustained delivery to the target tissue...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184827/electrospinning-and-electrospray-of-bio-based-and-natural-polymers-for-biomaterials-development
#3
REVIEW
Rosane M D Soares, Nataly M Siqueira, Molamma P Prabhakaram, Seeram Ramakrishna
Over nearly 70 years, polymers have revolutionized the global economy, manufacturing and, mainly, the fields which require biocompatible materials, as food technology and packaging, controlled drug delivery, tissue engineering, regenerative medicine, wound dressing, anti-allergy textiles, and personal care. While new high-performance polymers were produced from fossil-based sources to meet the functional performance demands of new applications, Earth has been polluted by the operation of factories that released CO2 to the atmosphere during the production of synthetic polymers...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184826/antiviral-activity-of-multifunctional-composite-based-on-tio-2-modified-hydroxyapatite
#4
Naruporn Monmaturapoj, Autcharaporn Sri-On, Wattana Klinsukhon, Kobporn Boonnak, Chureerat Prahsarn
An antiviral activity of TiO2 -modified hydroxyapatite composite (HA/TiO2 ) had been investigated. The HA/TiO2 composite (HA50:Ti50) was prepared by a solid state reaction method followed by calcination at 650 °C for 2 h. Phase formations and morphologies of the obtained HA/TiO2 composite powders were determined using XRD and SEM. XRD result confirmed that HA/TiO2 composite was successfully prepared. SEM revealed small crystals of anatase TiO2 embedded in larger HA crystals. A strong antiviral activity against H1N1 Influenza A Virus was observed at 0...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184825/strain-and-damage-sensing-performance-of-biocompatible-smart-cnt-uhmwpe-nanocomposites
#5
S K Reddy, S Kumar, K M Varadarajan, P R Marpu, Tejendra K Gupta, M Choosri
Herein, we report strain- and damage-sensing performance of biocompatible smart CNT/UHMWPE nanocomposites for the first time. CNT/UHMWPE nanocomposites are fabricated by solution mixing followed by compression molding. The surface morphology, microstructural properties, thermal decomposition and stability, glass transition temperature and thermal conductivity of the nanocomposites are characterized. The degree of crystallinity of CNT/UHMWPE nanocomposites is found to have a maximum value of 52% at 0.1 wt% CNT loading...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184824/electrochemical-sensing-of-cholesterol-by-molecularly-imprinted-polymer-of-silylated-graphene-oxide-and-chemically-modified-nanocellulose-polymer
#6
T S Anirudhan, J R Deepa, Binussreejayan
Silylated Graphene oxide-grafted-chemically modified nanocellulose (Si-GO-g-CMNC) is fabricated for selective sensing of Cholesterol. Zinc oxide (ZnO) incorporated in chemically modified nanocellulose (CMNC) for enhancing the conducting nature. The sensitivity of sensor was checked by modifying the glassy carbon electrode surface (GCE) with Si-GO-g-CMNC and the electro chemical studies were conducted with cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The physical and electrical properties of the sensor were analyzed by FTIR, Raman Spectroscopy, XRD, SEM, EDS and AFM techniques...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184823/synthesis-characterization-and-in-vitro-analysis-of-%C3%AE-fe-2-o-3-gdfeo-3-biphasic-materials-as-therapeutic-agent-for-magnetic-hyperthermia-applications
#7
Sunayan Deka, Varun Saxena, Abshar Hasan, Pranjal Chandra, Lalit M Pandey
The use of gadolinium orthoferrite for biomedical application like as contrast agents for magnetic resonance imaging (MRI) has been found to be very promising due to its fascinating properties. The present study focuses on the determination of the effect of the gadolinium concentration in the formation biphasic α-Fe2 O3 -GdFeO3 for hyperthermia applications. An in-situ sol-gel technique was adopted for the synthesis of biphasic orthoferrites with four different gadolinium concentrations. The XRD analysis confirmed the formation of gadolinium orthoferrites after heat treatment at 1000 °C, 1100 °C, and 1200 °C...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184822/incorporation-of-ce-3-ions-into-dodecatungstophosphoric-acid-for-the-production-of-biodiesel-from-waste-cooking-oil
#8
Dan Zhang, Xueyan Zhang, Yiming Li, Shengtian Wang, Xiaohong Wang, Zijiang Jiang
A series of cerium-exchanged dodecatungstophosphates Cex H3-3x PW12 O40 (Cex H3-3x PW, x = 0.4, 0.6, 0.7, 0.8, 0.9, and 1.0) were designed and characterized by Fourier transform infrared spectroscopy (FT-IR), pyridine adsorption IR spectra, X-ray diffraction (XRD), and temperature programmed desorption of ammonia (NH3 -TPD). The activity of these catalysts was evaluated for the generation of biodiesel from waste cooking oil (WCO) with 27 wt% of free fatty acids (FFAs) and 1 wt% of water. Compared to theri parent H3 PW12 O40 , Cex H3-3x PW showed higher activity for esterification of FFAs and transesterification of triglyceride to mono-alkyl esters of fatty acids (FAMEs) in one-pot...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184821/irmof-3-a-fluorescent-nanoscale-metal-organic-frameworks-for-selective-sensing-of-glucose-and-fe-iii-ions-without-any-modification
#9
Amit Kumar, Angshuman Ray Chowdhuri, Archana Kumari, Sumanta Kumar Sahu
The amine functionalized isoreticular metal-organic framework-3 (IRMOF-3) is synthesized by hydrothermal method. Till now, it's widely used in the area of gas separation, adsorption, and catalysis due to large surface area, structural stability, and tunability. Here, we have reported the use of fluorescent nanoscale IRMOF-3 for highly selective detection of glucose as well as Fe3+ ions without any modification. This is due to NH2 and COOH groups are present on the surface of IRMOF-3 to bind cis-diols of the glucose molecule via host-guest interaction, and Fe3+ ions via ligand to metal charge transfer...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184820/biomimetic-synthesis-of-silver-nanoparticles-using-matricaria-chamomilla-extract-and-their-potential-anticancer-activity-against-human-lung-cancer-cells
#10
Mehdi Dadashpour, Akram Firouzi-Amandi, Mohammad Pourhassan-Moghaddam, Mohammad Jafar Maleki, Narges Soozangar, Farhad Jeddi, Mohammad Nouri, Nosratollah Zarghami, Younes Pilehvar-Soltanahmadi
Herbs having various natural substances can be utilized for the biosynthesis of Silver nanoparticles (AgNPs) and act as a stable, reliable and biocompatible alternative instead of the current physical and chemical approaches. It has been reported that Matricaria chamomilla possesses unique properties, especially anti-cancerous effects. The objective of the current work was to assess the chemical characteristics and anticancer effects of biosynthesized AgNPs applying aqueous extracts of M. chamomilla against A549 lung cancer cells...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184819/ingenious-ph-sensitive-etoposide-loaded-folic-acid-decorated-mesoporous-silica-carbon-dot-with-carboxymethyl-%C3%AE-cyclodextrin-gatekeeper-for-targeted-drug-delivery-and-imaging
#11
Marziyeh Poshteh Shirani, Behzad Rezaei, Taghi Khayamian, Mohammad Dinari, Fazileh Hosseini Shamili, Mohammad Ramezani, Mona Alibolandi
A new strategy is reported for the synthesis of label-free fluorescent mesoporous silica (MS) by the introduction of fluorescent carbon dots in the MSs (MSCDs) in this work. Etoposide (ETO) loaded MSCDs have been used as a drug model. Carboxymethyl β-cyclodextrin (CβCD) used as a gatekeeper agent was attached to amine-functionalized MSCDs to retain ETO molecules inside the nanocarrier. In order to target the nanocarrier to the site of action, folic acid (FA) was grafted onto the MSCDs surface (FA-CβCD-MSCDs)...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184818/biological-effect-of-hydrothermally-synthesized-silica-nanoparticles-within-crystalline-hydroxyapatite-coatings-for-titanium-implants
#12
Amanda Bartkowiak, Katarzyna Suchanek, Elżbieta Menaszek, Barbara Szaraniec, Janusz Lekki, Marcin Perzanowski, Marta Marszałek
Development of functional coatings for artificial bone implants that strengthen the osseointegration and accelerate bone healing processes is urgently needed in the biomedical field. In this study we present biological effect of novel composite coatings with different concentration of silica nanoparticles within crystalline hydroxyapatite matrix (HAp-SiO2 ) synthesized on titanium under hydrothermal conditions. Samples were analyzed for their elemental composition, structure, bioactivity and in vitro cytotoxicity...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184817/harnessing-the-pleiotropic-effects-of-atorvastatin-fenofibrate-combination-for-cardiovascular-stents
#13
Purandhi Roopmani, Uma Maheswari Krishnan
Atorvastatin and fenofibrate have been conventionally employed as lipid-lowering agents. They also exhibit beneficial effects in the treatment of endothelial dysfunction, oxidative stress and vascular inflammation due to their pleiotropic effects that include vasodilatory and anti-inflammatory effects. These pleiotropic effects may serve to overcome the drawbacks of late stent thrombosis and delayed endothelialization that plague conventional drug eluting stents. However, the combination has not been explored yet as therapeutic coatings in drug eluting stents...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184816/electroactive-biomaterial-surface-engineering-effects-on-muscle-cells-differentiation
#14
S Ribeiro, A C Gomes, I Etxebarria, S Lanceros-Méndez, C Ribeiro
Even though skeletal muscle cells can naturally regenerate as a response to insignificant tissue damages, more severe injuries can cause irreversible loss of muscle cells mass and/or function. Until now, cell therapies are not a good approach to treat those injuries. Biomaterials such as poly(vinylidene fluoride), PVDF, can improve muscle regeneration by presenting physical cues to muscle cells that mimic the natural regeneration environment. In this way, the ferroelectric and piezoelectric properties of PVDF offer new opportunities for skeletal muscle tissue engineering once the piezoelectricity is an electromechanical effect that can be used to provide electrical signals to the cells, upon mechanical solicitations, similar to the ones found in several body tissues...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184815/an-analysis-on-the-potential-of-diode-pumped-solid-state-lasers-for-dental-materials
#15
Roberto De Santis, Teresa Russo, Antonio Gloria
Material structure-property relationship is strongly related to the employed process technology. Over the past years, laser processing of engineering materials has been proposed in many fields and different uses for diode lasers have been found in dentistry. In this contest, the potential of GaN- and InGaN-based laser diodes to cure dental materials was analysed. Two wavelengths of 405 nm and 445 nm were used as heat or light sources for warm condensation of gutta-percha, light transmission in dental posts and brackets or light curing of dental composites...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184814/characterization-of-chemically-treated-ti-zr-system-alloys-for-dental-implant-application
#16
Jairo M Cordeiro, Leonardo P Faverani, Carlos R Grandini, Elidiane C Rangel, Nilson C da Cruz, Francisco H Nociti Junior, Amanda B Almeida, Fabio B Vicente, Bruna R G Morais, Valentim A R Barão, Wirley G Assunção
Materials and surfaces developed for dental implants need to withstand degradation processes that take place in the oral cavity. Therefore, the aim of the study was to develop and evaluate the topographical, mechanical, chemical, electrochemical and biological properties of Ti-xZr alloys (x = 5, 10, and 15 wt%) with two surface features (machined and double acid etched). Commercially pure titanium (cpTi) and Ti-6Al-4V alloy were used as controls. Surface characterization was performed using dispersive energy spectroscopy, X-ray diffraction, scanning electron microscopy, atomic force microscopy, profilometry and surface energy...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184813/antibacterial-effect-and-biocompatibility-of-a-novel-nanostructured-zno-coated-gutta-percha-cone-for-improved-endodontic-treatment
#17
M J Alves, L Grenho, C Lopes, J Borges, F Vaz, I P Vaz, M H Fernandes
This work explored a novel approach to enhance the antibacterial activity of commercial Gutta-percha (GP) cones, the most commonly used core filling materials used in endodontic treatment. The reported procedure involved an argon (Ar) plasma treatment (PT) of the GP cone surface, followed by the deposition of a ZnO thin film by magnetron sputtering. The resulting surfaces were evaluated for surface topography, antibacterial activity against Enterococcus faecalis and Staphylococcus aureus, and cytocompatibility with human osteoblastic cells...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184812/sodium-caseinate-magnesium-aluminum-silicate-nanocomposite-films-for-modified-release-tablets
#18
Wanassnant Kajthunyakarn, Duangkamon Sakloetsakun, Thaned Pongjanyakul
The aim of this study was to investigate the effect of clay, magnesium aluminum silicate (MAS), on the properties of sodium caseinate (SC) dispersions and films. Moreover, the SC-MAS dispersions were evaluated for film coating of modified-release tablets. The results showed that MAS addition led to particle flocculation and viscosity synergism in the SC-MAS dispersions. Exfoliated or intercalated nanocomposites of the SC-MAS films could be formed because of the molecular interaction of both components via hydrogen bonding...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184811/hemocompatibility-of-plasma-electrolytic-oxidation-peo-coated-mg-re-and-mg-zn-ca-alloys-for-vascular-scaffold-applications
#19
Nadja Kröger, Alexander Kopp, Mareike Staudt, Mihaela Rusu, Alexander Schuh, Elisa A Liehn
Percutaneous transluminal coronary angioplasty and subsequent vascular scaffold implantation remains the prevalent invasive treatment of coronary heart disease. In-stent restenosis remained a problem with bare metal stents, until drug-eluting stents were introduced. The inhibition of the healing process by the antimitotic drug coating and the permanent metallic remnant can promote sub-acute and delayed stent thrombosis. Thus, the development of biodegradable stents emerged as a subject of research. Magnesium-based bioabsorbable devices can provide sufficient radial force in the acute phase of vessel-treatment and degrade thoroughly in aqueous environment, making them potential new candidates for vascular scaffold applications...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/30184810/molecular-insights-to-alkaline-based-bio-fabrication-of-silver-nanoparticles-for-inverse-cytotoxicity-and-enhanced-antibacterial-activity
#20
Suresh K Verma, Ealisha Jha, Pritam Kumar Panda, Arun Thirumurugan, Shubhransu Patro, S K S Parashar, Mrutyunjay Suar
High demand for silver nanoparticles due to their extensive applications in different field has raised need of eco-friendly green synthesis with determined biomedical effects. This study proposes a novel rapid controlled alkaline based green synthesis of antibacterial silver nanoparticles from Calotropis gigantea for reduced cytotoxic effects. Silver nanoparticles termed as FAg, FAg1N, and FAg5N were synthesized with the help of floral extract of Calotropis gigantea as reducing and capping agent in presence of UV light and NaOH for catalysis and were characterized for their physiochemical properties by FESEM, DLS, UV-Visible spectrophotometry and FTIR...
November 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
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