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Materials Science & Engineering. C, Materials for Biological Applications

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https://www.readbyqxmd.com/read/29853152/efficacy-of-saccharides-bio-template-on-structural-morphological-optical-and-antibacterial-property-of-zno-nanoparticles
#1
A Dhanalakshmi, A Palanimurugan, B Natarajan
Mono, di and polysaccharides of glucose (C6 H12 O6 ), sucrose (C12 H24 O12 ) and starch (C6 H12 O6 )n bio-template ZnO nanoparticles (NPs) has prepared by chemical precipitation method. Saccharides bio-template ZnO (SBts-ZnO) NPs were efficiently prepared for their structural and optical properties were examined by using XRD, FE-SEM, AFM, FTIR, UV and PL techniques. All the samples are polycrystalline nature with a preferential orientation depending on the (1 0 1) plane. The reduction of crystalline size by utilizing glucose, sucrose and starch bio-template of ZnO NPs...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853151/decoration-of-1-d-nano-bioactive-glass-on-reduced-graphene-oxide-sheets-strategies-and-in-vitro-bioactivity-studies
#2
Ashok Raja C, Balakumar S, Bargavi P, Rajashree P, Anandkumar B, George R P, Kamachi Mudali U
45S5 Bioglass® is the most widely studied class of bioceramic in the field of dental and orthopedics. The present study highlights, one-dimensional bioactive glass nanorods (BGNR) of 45S5 composition synthesized by tuning the parameters of sol-gel process and hybridized with two-dimensional reduced graphene oxide sheets (rGO). BGNR was integrated with rGO by three different methods to form nano hybrids of rGO/BGNR. The prepared BGNR revealed combeite high mineral phase (Na5.27 Ca3 Si6 O18 ) whereas nano hybrids exhibited calcite mineral phase (CaCO3 ) along with combeite in XRD analysis...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853150/effect-of-calcium-pyrophosphate-on-microstructural-evolution-and-in-vitro-biocompatibility-of-ti-35nb-7zr-composite-by-spark-plasma-sintering
#3
L Zhang, J Tan, Z Y He, Y H Jiang
β-type Ti-35Nb-7Zr alloy has attracted considerable attentions as a bone implant material. The alloy, however, has poor bioactivity, which difficult to form a strong osseointegration between the bone tissues. Combining Ti alloy with a bioactive and biodegradable ceramic has been of interest to researchers. But the large difference in physicochemical property of high-melting metal and ceramic elements would bring the manufacturing restriction. In this work, Ti-35Nb-7Zr-CPP composites were fabricated with mechanical alloy of Ti, Nb, Zr and Nano calcium pyrophosphate (CPP) powders mixture followed by spark plasma sintering (SPS) routes...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853149/retraction-notice-to-effects-of-high-energy-electro-pulsing-treatment-on-microstructure-mechanical-properties-and-corrosion-behavior-of-ti-6al-4v-alloy-msec-volume-49-year-2015-pages-851-860
#4
Xiaoxin Ye, Lingsheng Wang, Zion T H Tse, Guoyi Tang, Guolin Song
No abstract text is available yet for this article.
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853148/improved-near-infrared-mediated-hydrogel-formation-using-diacrylated-pluronic-f127-coated-upconversion-nanoparticles
#5
Kihak Gwon, Eun-Jung Jo, Abhishek Sahu, Jae Young Lee, Min-Gon Kim, Giyoong Tae
In situ hydrogel synthesis based on photopolymerization has been recognized as a promising strategy that can be used for tissue augmentation. In this study, we developed an efficient in situ gelation method to prepare bulk hydrogels via near infrared (NIR)-mediated photopolymerization using acrylated polyethylene glycol and diacrylated Pluronic F127-coated upconversion nanoparticles (UCNPs). In our system, upon 980-nm laser irradiation, UCNPs transmit visible light, which triggers the activation of eosin Y to initiate polymerization...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853147/advances-on-graphene-based-nanomaterials-for-biomedical-applications
#6
REVIEW
Ying Qu, Feng He, Chenggong Yu, Xuewu Liang, Dong Liang, Long Ma, Qiuqiong Zhang, Jiahui Lv, Jingde Wu
Graphene-based nanomaterials, such as graphene oxide and reduced graphene oxide, have been attracting increasing attention in the field of biology and biomedicine over the past few years. Incorporation of these novel materials with drug, gene, photosensitizer and other cargos to construct novel delivery systems has witnessed rapid advance on the basis of their large surface area, distinct surface properties, excellent biocompatibility and pH sensitivity. Moreover, the inherent photothermal effect of these appealing materials enables them with the ability of killing targeting cells via a physical mechanism...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853146/biomedical-application-and-controlled-drug-release-of-electrospun-fibrous-materials
#7
REVIEW
Huiling Cheng, Xiaoye Yang, Xin Che, Mingshi Yang, Guangxi Zhai
Electrospinning, as a nanotechnology, is able to produce polymeric fibers materials with nanoscale structure which are also named electrospun fibers material (EFM). These EFMs can be used in many biomedical applications such as wound dressing, tissue engineering, and medical textile materials. Over the last decades, electrospun nanofibers also have been applied to drug delivery such as orodispersible film, solid dispersion and various controlled release dosage forms due to many properties such as high surface to volume ratio, high porous, ease of fabrication and adaptability and so on...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853145/do-physico-chemical-properties-of-silver-nanoparticles-decide-their-interaction-with-biological-media-and-bactericidal-action-a-review
#8
REVIEW
Vikram Pareek, Rinki Gupta, Jitendra Panwar
The unprecedented increase in antibiotic resistance in this era has resuscitated the attention of scientific community to exploit silver and its various species as antimicrobial agents. Plenty of studies have been done to measure the antimicrobial potential of silver species (cationic silver, metallic Ag0 or silver nanoparticles, silver oxide particulates etc.) and indicated that membrane damage, oxidative stress, protein dysfunction and DNA damage to be the possible cause of injury to the microbial cell. However, the precise molecular mechanism of their mode of action has remained unclear, which makes an obstacle towards the generation of potential antibacterial agent against various pathogenic and multidrug resistant (MDR) bacteria...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853144/biofunctionalized-peptide-nanofiber-based-composite-scaffolds-for-bone-regeneration
#9
REVIEW
Bin He, Jinqiu Zhao, Yunsheng Ou, Dianming Jiang
Bone tissue had moderate self-healing capabilities, but biomaterial scaffolds were required for the repair of some defects such as large bone defects. Peptide nanofiber scaffolds demonstrated important potential in regenerative medicine. Functional modification and controlled release of signal molecules were two significant approaches to increase the bioactivity of biofunctionalized peptide nanofiber scaffolds, but peptide scaffolds were limited by insufficient mechanical strength. Thus, it was necessary to combine peptide scaffolds with other materials including polymers, hydroxyapatite, demineralized bone matrix (DBM) and metal materials based on the requirement of different bone defects...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853143/biodegradable-dendrimers-for-drug-delivery
#10
REVIEW
Da Huang, Decheng Wu
Dendrimers, as a type of artificial polymers with unique structural features, have been extensively explored for their applications in biomedical fields, especially in drug delivery. However, one important concern about the most commonly used dendrimers exists - the nondegradability, which may cause side effects induced by the accumulation of synthetic polymers in cells or tissues. Therefore, biodegradable dendrimers incorporating biodegradability with merits of dendrimers such as well-defined architectures, copious internal cavities and surface functionalities, are much more promising for developing novel nontoxic drug carriers...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853142/characterization-of-natural-hydroxyapatite-originated-from-fish-bone-and-its-biocompatibility-with-osteoblasts
#11
Pujie Shi, Meng Liu, Fengjiao Fan, Cuiping Yu, Weihong Lu, Ming Du
Hydroxyapatite (HAP) was very attractive for using as bone implant material for a long period due to the close similarity with natural bone in composition and osteoconductive properties. In this study, three kinds of natural HAP (nHAP) derived from rainbow trout (Onchorynchus mkiss), cod (Gadus) and salmon (Oncorhynchus keta) bones were prepared using thermal calcination method for the first time. Resultant nHAPs were characterized by fourier transform infrared spectroscopy (FT-IR), x-ray diffraction analysis (XRD), field-emission scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) analysis...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853141/novel-ph-responsive-tobramycin-embedded-micelles-in-nanostructured-multilayer-coatings-of-chitosan-heparin-with-efficient-and-sustained-antibacterial-properties
#12
Wenhao Zhou, Zhaojun Jia, Pan Xiong, Jianglong Yan, Ming Li, Yan Cheng, Yufeng Zheng
To endow orthopaedic implants with satisfactory antibacterial properties, the design and development of antibiotic coating on the surface of implants is highly desired. In this work a novel and facile strategy was developed to form pH-responsive layer-by-layer (LbL) films implanted with polymeric micelles as nano-vehicles loaded with charge-weak antibiotic drugs, enabling high drug loading efficiency. Negatively charged tobramycin (Tob)-embeded heparin miscells (HET) and positively charged chitosan (CHT) were exploited as a pH-responsive LBL multilayer building block, respectively...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853140/neurogenic-differentiation-of-adipose-derived-stem-cells-on-graphene-based-mat
#13
Zhang-Qi Feng, Ke Yan, Chuanmei Shi, Xuran Xu, Ting Wang, Ruitao Li, Wei Dong, Jie Zheng
Adipose derived stem cells (ADSCs) have been proved as an abundant and accessible cell source with the ability to differentiate into neuron-like cells. However, the low differentiation efficiency puts forward an important challenge to practical applications in clinic. Considering of the good biocompatibility of graphene-based materials and the potential interaction between graphene and cells mentioned in previous studies, herein, we investigated the effect of graphene oxide (GO) and reduced graphene oxide (rGO) mats on neurogenic differentiation of the ADSCs...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853139/surface-characteristics-and-antimicrobial-properties-of-modified-catheter-surfaces-by-polypyrogallol-and-metal-ions
#14
Praveen Kumar Balne, Sriram Harini, Chetna Dhand, Neeraj Dwivedi, Madhavi Latha Somaraju Chalasani, Navin Kumar Verma, Veluchamy Amutha Barathi, Roger Beuerman, Rupesh Agrawal, Rajamani Lakshminarayanan
Catheter associated infections (CAIs) are the major cause of nosocomial infections leading to increased morbidity, mortality rates and economical loss. Though the antibiotic coated surface modified catheters are reported to be effective in preventing CAIs, presence of sub-lethal concentrations of antibiotics in long term instilled catheters poses a risk of development and spread of drug resistant microbial strains. Herein, we have developed an antibiotic-free alternative strategy to coat catheter surfaces using pyrogallol (PG) and metal ions (Ag+ /Mg2+ )...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853138/injectable-synthetic-hydrogel-for-bone-regeneration-physicochemical-characterisation-of-a-high-and-a-low-ph-gelling-system
#15
Manuel Schweikle, Thomas Zinn, Reidar Lund, Hanna Tiainen
Hybrid poly(ethylene glycol)-co-peptide hydrogels are a versatile platform for bone regeneration. For the use as injectable scaffolds, a good understanding of reaction kinetics and physical properties is vital. However, these factors have not yet been comprehensively illuminated. We show that gelation time can be effectively controlled by pH without affecting the elasticity of the formed hydrogels. Maleimide functionalised PEG gels at lower pH and produces more densely cross-linked networks than vinylsulfone functionalised PEG...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853137/titanium-dioxide-nanotubes-functionalized-with-cratylia-mollis-seed-lectin-cramoll-enhanced-osteoblast-like-cells-adhesion-and-proliferation
#16
Weslley F Oliveira, Germana M M Silva, Paulo E Cabral Filho, Adriana Fontes, Maria D L Oliveira, César A S Andrade, Márcia V Silva, Luana C B B Coelho, Giovanna Machado, Maria T S Correia
An alternative to accelerate the osseointegration on titanium dioxide nanotubes (TNTs) used in osseointegrated implants is through the functionalization of these nanostructured surfaces with biomolecules. In this work, we immobilized a lectin with recognized mitogenic activity, the Cramoll lectin, extracted from Cratylia mollis seeds, on surfaces modified by TNTs. For the immobilization of Cramoll on TNTs surfaces, we used the Layer-by-Layer technique (LbL) by growing five alternate layers of poly(allylamine) hydrochloride (PAH) and poly(acrylic) acid (PAA); lastly we incubated the lectin, at different concentrations, with the TNTs-LbL...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853136/antiosteoporotic-effect-of-hydrilla-verticillata-against-lead-induced-damage-in-bone-samples-of-edible-fish-labeo-rohita-an-ftir-approach
#17
S Pandi Prabha, Johanna Rajkumar, S Suresh, S Karthikeyan
No abstract text is available yet for this article.
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853135/biofunctionalization-of-tio-2-surfaces-with-self-assembling-oligopeptides-in-different-ph-and-ionic-strength-conditions-charge-effects-and-molecular-organization
#18
S Franchi, V Secchi, M Santi, M Dettin, A Zamuner, C Battocchio, G Iucci
Self-assembling peptides (SAPs) were investigated by means of XPS and Angular Dependent NEXAFS spectroscopies, with the aim to probe the influence of pH and Ionic Strength conditions on the chemical structure and molecular organization of SAPs anchored on titania surfaces. XPS at the C1s, N1s, O1s core levels allowed to study surfaces and biomolecule/substrate interfaces. NEXAFS data allowed ascertaining that SAPs molecular structure is preserved upon grafting to the titania surface. Angular Dependent NEXAFS was used to investigate the influence of environmental conditions on the molecular organization behaviour...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853134/biomechanical-analysis-of-different-implant-abutments-interfaces-in-different-bone-types-an-in-silico-analysis
#19
Eduardo P Pellizzer, Cleidiel A A Lemos, Daniel A F Almeida, Victor E de Souza Batista, Joel F Santiago Júnior, Fellippo R Verri
The purpose of this study was to analyze the stress distribution of bone tissue around implants with different implant-abutment interfaces: platform switching (PSW); external hexagon (EH) and Morse taper (MT) with different diameters (regular: Ø 4 mm and wide: Ø 5 mm), bone types (I-IV) and subjected to axial and oblique load conditions using three-dimensional finite element analysis (3D-FEA). Sixteen 3D models of various configurations were simulated using InVesalius, Rhinoceros 3D 4.0, and SolidWorks 2011 software, and processed using Femap 11...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29853133/polymer-coating-on-a-micropillar-chip-for-robust-attachment-of-puramatrix-peptide-hydrogel-for-3d-hepatic-cell-culture
#20
Alexander David Roth, Pratap Lama, Stephen Dunn, Stephen Hong, Moo-Yeal Lee
For better mimicking tissues in vivo and developing predictive cell models for high-throughput screening (HTS) of potential drug candidates, three-dimensional (3D) cell cultures have been performed in various hydrogels. In this study, we have investigated several polymer coating materials to robustly attach PuraMatrix peptide hydrogel on a micropillar chip for 3D culture of Hep3B human hepatic cells, which can be used as a tool for high-throughput assessment of compound hepatotoxicity. Among several amphiphilic polymers with maleic anhydride groups tested, 0...
September 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
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