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Probiotics and Antimicrobial Proteins

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https://www.readbyqxmd.com/read/29218506/in-silico-discovery-of-novel-ligands-for-antimicrobial-lipopeptides-for-computer-aided-drug-design
#1
REVIEW
Satya Eswari Jujjavarapu, Swasti Dhagat
The increase in antibiotic-resistant strains of pathogens has created havoc worldwide. These antibiotic-resistant pathogens require potent drugs for their inhibition. Lipopeptides, which are produced as secondary metabolites by many microorganisms, have the ability to act as potent safe drugs. Lipopeptides are amphiphilic molecules containing a lipid chain bound to the peptide. They exhibit broad-spectrum activities against both bacteria and fungi. Other than their antimicrobial properties, they have displayed anti-cancer properties as well, but their mechanism of action is not understood...
December 7, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29218505/antibacterial-and-antibiofilm-activity-of-lactic-acid-bacteria-isolated-from-traditional-artisanal-milk-cheese-from-northeast-china-against-enteropathogenic-bacteria
#2
Xingyang Cui, Yunjia Shi, Shanshan Gu, Xin Yan, Hongyan Chen, Junwei Ge
The present study aims to investigate the probiotic properties of novel strains of lactic acid bacteria isolated from traditional artisanal milk cheese from Northeast China and to explore their antibacterial activity against enteropathogenic bacteria. Of the 321 isolates, 86 exhibited survival in low pH, resistance to pancreatin, and tolerance to bile salts; of these, 12 inhibited the growth of more than seven enteropathogenic bacteria and exhibited antibiofilm activities against Staphylococcus aureus CMCC26003 and/or Escherichia coli CVCC230...
December 7, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29209903/influence-of-a-co-culture-of-streptococcus-thermophilus-and-lactobacillus-casei-on-the-proteolysis-and-ace-inhibitory-activity-of-a-beverage-based-on-reconstituted-goat-whey-powder
#3
Áurea Marcela de Souza Pereira, Daniely Rayane Bezerra de Farias, Blenda Brito de Queiroz, Michelangela Suelleny de Caldas Nobre, Mônica Tejo Cavalcanti, Hévila Oliveira Salles, Karina Maria Olbrich Dos Santos, Ana Claudia Dantas de Medeiros, Eliane Rolim Florentino, Flávia Carolina Alonso Buriti
The potential for reusability of whey is of concern due to its substantial nutritional value and, second, in view of the need to reduce environmental impact. The use of goat whey powder in the production of a fermented dairy beverage using a Lactobacillus casei culture as adjunct shows a good prospect of a food product with hypotensive activity. This study investigated the microbial viability, proteolysis and angiotensin-converting enzyme (ACE) inhibitory activity of a fermented dairy beverage produced with goat whey powder and a probiotic culture of L...
December 5, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29204797/prevention-of-renal-scarring-in-acute-pyelonephritis-by-probiotic-therapy-an-experimental-study
#4
Nastaran Sabetkish, Shabnam Sabetkish, Mohammad Javad Mohseni, Abdol-Mohammad Kajbafzadeh
We evaluated the protective effects of probiotic administration as a prophylaxis treatment and immediately after fever onset in increasing the immune response and decreasing the renal scarring in a rat model of acute pyelonephritis. Twenty-four rats were apportioned to three groups. In GI (n = 8), the rats were injected with direct inoculation of Escherichia coli into the right kidney. In GII (n = 8), the rats received a probiotic regimen 1 month before E. coli injection and the probiotic regimen was continued for the next 2 months...
December 4, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29196921/viability-and-stress-response-of-putative-probiotic-lactobacillus-plantarum-strains-in-honey-environment
#5
Bemmo Kamdem Ulrich Landry, Zambou Ngoufack François, Rui-Yan Wang, Zhu Taicheng, Yin Li
Due to problem of preservation of dairy products which serve as a matrix for probiotics, it is challenging to use these probiotics as food supplements in many developing countries. To determine the suitability of the Lactobacillus strains for exploitation as probiotics in honey, we investigated the effect of their storage on the viability, functionality, and the mechanism associated with their protective effect. Three isolates obtained from our laboratory collection were identified through amplification of the 16S rRNA gene...
December 1, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29196920/probiotic-bacillus-coagulans-gbi-30-6086-improves-protein-absorption-and-utilization
#6
Ralf Jäger, Martin Purpura, Sean Farmer, Howard A Cash, David Keller
Probiotics offer numerous health benefits, including digestive and immune health. Improved digestive health is linked to a more efficient absorption of important nutrients from our diet. This review focused on the rationale of using the probiotic Bacillus coagulans GBI-30, 6086 to aid protein absorption and utilization. B. coagulans GBI-30, 6086 can withstand the acidic environment of the stomach to reach the intestine where it germinates. Once active in the small intestine after germination, it has been shown to aid the digestion of carbohydrates and proteins...
December 1, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29196919/the-combined-efficiency-of-dietary-isomaltooligosaccharides-and-bacillus-spp-on-the-growth-hemato-serological-and-intestinal-microbiota-indices-of-caspian-brown-trout-salmo-trutta-caspius-kessler-1877
#7
Maryam Aftabgard, Alireza Salarzadeh, Mahmoud Mohseni, Amir Houshang Bahri Shabanipour, Mohammad Ebrahim Jalil Zorriehzahra
The combined effects of a commercial probiotic, BetaPlus®, and a prebiotic, isomaltooligosaccharides (IMOS) on the growth, survival rate, intestinal microbiota, and hemato-immunological parameters were evaluated in Caspian brown trout (Salmo trutta caspius Kessler, 1877). Caspian brown trout fingerlings (~ 9 g) were fed a control diet (basal diet) or a synbiotic diet (the basal diet + 2 g kg-1 IMOS + 1 g kg-1 BetaPlus®) for 7 weeks. At the end of this trial, fish fed the synbiotic diet showed significant improvements in body weight increase, feed conversion ratio, and survival rate compared with fish fed the control diet (P < 0...
December 1, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29185234/newly-isolated-lactobacilli-strains-from-algerian-human-vaginal-microbiota-lactobacillus-fermentum-strains-relevant-probiotic-s-candidates
#8
Liza Ouarabi, Yasmina Ait Chait, Hamza Ait Seddik, Djamel Drider, Farida Bendali
Lactobacilli strains are considered as a preventive means for treatment of vaginal infections or post-antibiotic treatment to repopulate the vaginal mucosa. This study aimed at establishing the vaginal lactobacillus profile of Algerian women with different vaginal diseases. Afterwards, lactobacilli isolated from swabs were in vitro characterized for their probiotic hallmarks. This prospective study allowed isolation of 44 Lactobacillus strains and 160 potentially pathogens, among which are Escherichia coli (50 isolates), Staphylococcus sp...
November 28, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29181803/functional-characterization-of-probiotic-potential-of-novel-pigmented-bacterial-strains-for-aquaculture-applications
#9
Sekar Jinendiran, Seenivasan Boopathi, Natesan Sivakumar, Gopal Selvakumar
The bioprospecting proficient of novel pigmented probiotic strains with respect to aquaculture industry was unexplored hitherto. In this study, we investigated the probiotic potential of novel pigmented bacterial strains isolated from the indigenous soil sediments in their vicinal habitats, which were screened for their antimicrobial activity against aquatic pathogens using agar well diffusion assay. The strains namely Exiguobacterium acetylicum (S01), Aeromonas veronii (V03), and Chryseobacterium joostei (V04) were phenotypically identified and confirmed by 16S rRNA gene sequence analysis...
November 27, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29181802/study-and-understanding-behavior-of-alginate-inulin-synbiotics-beads-for-protection-and-delivery-of-antimicrobial-producing-probiotics-in-colonic-simulated-conditions
#10
Abdelbasset Atia, Ahmed Gomaa, Benoit Fernandez, Muriel Subirade, Ismail Fliss
According to the World Health Organization (WHO), using antibiotics as growth promoters for livestock-particularly swine-is the principal cause of antibiotic resistance. It is therefore clear that finding an alternative to antibiotics becomes an emergency. Hundreds of recent studies have appointed probiotics as potential candidates to replace or to be used in combination with antibiotics. However, bringing probiotics alive to the colon-their site of action-remains a big challenge because of different physiological barriers encountered in proximal gastrointestinal tract (GIT) such as acidic pH and bile salts that may affect the viability of probiotic cultures...
November 27, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29177756/leucocin-c-607-a-novel-bacteriocin-from-the-multiple-bacteriocin-producing-leuconostoc-pseudomesenteroides-607-isolated-from-persimmon
#11
Yi-Sheng Chen, Hui-Chung Wu, Cheng-Yu Kuo, Yu-Wei Chen, Sin Ho, Fujitoshi Yanagida
Leuconostoc pseudomesenteroides 607, isolated from persimmon fruit, was found to have high inhibitory activity against Listeria monocytogenes and several other Gram-positive bacteria. Inhibitory substances were purified from culture supernatant by ion-exchange chromatography, Sep-Pak C18 cartridge, and reverse-phase high-performance liquid chromatography (RP-HPLC). Two antibacterial peptides were observed during the purification procedures. One of these peptides had a molecular size of 4623.05 Da and a partial N-terminal amino acid sequence of NH2-KNYGNGVHxTKKGxS, in which the YGNGV motif is specific for class IIa bacteriocins...
November 25, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29168155/in-silico-and-experimental-data-claiming-safety-aspects-and-beneficial-attributes-of-the-bacteriocinogenic-strain-enterococcus-faecalis-b3a-b3b
#12
Alaa Al Seraih, Yanath Belguesmia, Benoit Cudennec, John Baah, Djamel Drider
This study aimed at comparing the genome of Enterococcus faecalis B3A-B3B, a bacteriocinogenic strain recently isolated from a healthy Iraqi infant to those of Enterococci of clinical and beneficial grades. The putative genes gelE, cpd, efaAfm, ccf, agg, and cob coding for virulence factors were detected in B3A-B3B strain, which meanwhile resulted to be non-cytotoxic, non-hemolytic, devoid of inflammatory effects, and sensitive to most of the antibiotics tested except for clindamycin and trimethoprim, which resistance is usually ascribed to intrinsic nature...
November 22, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29168154/the-effect-of-probiotics-on-halitosis-a-systematic-review-and-meta-analysis
#13
REVIEW
Jun-Il Yoo, In-Soo Shin, Jae-Gyu Jeon, Yeon-Mi Yang, Jae-Gon Kim, Dae-Woo Lee
Although several studies have evaluated the inhibitory effect of probiotics on halitosis, findings are inconsistent. This systematic review and meta-analysis of randomized clinical trials (RCT) was conducted to summarize the evidence on the effect of probiotics on halitosis. RCT on any type of probiotic treatment with at least 2-week duration were identified through electronic databases (PubMed, EMBASE, Web of Science, and the Cochrane Central Register of Controlled Trials) and hand searched between 1946 and January 17, 2017...
November 22, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29164486/adaptation-and-probiotic-potential-of-lactobacilli-isolated-from-the-oral-cavity-and-intestines-of-healthy-people
#14
Yulia Chervinets, Vyacheslav Chervinets, Boris Shenderov, Ekaterina Belyaeva, Andrey Troshin, Sergey Lebedev, Valery Danilenko
The present study shows that, from 300 Lactobacillus strains isolated from the oral cavity and large intestine of 600 healthy people, only 9 had high antagonistic activity against pathogens and opportunistic pathogens. All antagonistic strains of lactobacilli have been identified by 16S rRNA sequencing and assigned to four species: Lactobacillus fermentum, Lactobacillus rhamnosus, Lactobacillus plantarum, and Lactobacillus casei. In addition, these lactobacilli appeared to be nonpathogenic and had some probiotic potential: the strains produced lactic acid and bacteriocins, showed high sensitivity to broad-spectrum antibiotics, and were capable of forming biofilms in vitro...
November 21, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29159445/probiotic-properties-and-cellular-antioxidant-activity-of-lactobacillus-plantarum-ma2-isolated-from-tibetan-kefir-grains
#15
Wei Tang, Chao Li, Zengguo He, Fen Pan, Shuo Pan, Yanping Wang
Lactobacillus plantarum MA2 was isolated from traditional Chinese Tibetan kefir grains. Its antioxidant properties had been demonstrated in vitro and in vivo previously. In the present study, the probiotic characteristics of this strain were further evaluated by investigating its acid and bile salt tolerances, cell surface hydrophobicity, and autoaggregation, respectively. In addition, the cellular antioxidant activity (CAA) assay was applied to test the antioxidant capacity of the isolate in different growth phases...
November 20, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29151250/mudskipper-boleophthalmus-pectinirostris-hepcidin-1-and-hepcidin-2-present-different-gene-expression-profile-and-antibacterial-activity-and-possess-distinct-protective-effect-against-edwardsiella-tarda-infection
#16
Jie Chen, Li Nie, Jiong Chen
Hepcidins are small cysteine-rich antimicrobial peptides that play an important role in fish immunity against pathogens. Most fish species have two or more hepcidin homologs that have distinct functions. This study investigated the immune functions of mudskipper (Boleophthalmus pectinirostris) hepcidin-1 (BpHep-1) and hepcidin-2 (BpHep-2) in vitro and in vivo. Upon infection with Edwardsiella tarda, the expression of BpHep-1 and BpHep-2 mRNA in immune tissues was significantly upregulated, but the expression profiles were different...
November 18, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29150754/detoxification-of-aflatoxin-b1-by-antifungal-compounds-from-lactobacillus-brevis-and-lactobacillus-paracasei-isolated-from-dairy-products
#17
Eman Zakaria Gomaa, Manal Farouk Abdelall, Omima Mohammed El-Mahdy
Aflatoxins are a large group of highly toxic, mutagenic, and carcinogenic mycotoxins produced by specific species of fungi. Potential contamination of food commodities by these compounds causes extensive damage that lead to great economic losses. This study explored the potential use of antifungal compounds, produced by Lactobacillus brevis and Lactobacillus paracasei, for growth inhibition and subsequent aflatoxin B1 production from select strains of Aspergillus flavus and Aspergillus parasiticus. Lactobacilli strains were isolated from traditional Egyptian dairy products, whereas fungal strains were isolated from infected cereal seeds...
November 18, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29124564/encapsulation-of-probiotics-proper-selection-of-the-probiotic-strain-and-the-influence-of-encapsulation-technology-and-materials-on-the-viability-of-encapsulated-microorganisms
#18
REVIEW
Aušra Šipailienė, Sigita Petraitytė
Probiotic encapsulation is an entire system that not only involves but also depends on many factors. Elements such as the encapsulation method itself, materials, environmental conditions, and last, but not least, the strain; all play an important role in the encapsulation process. The current paper focuses on the right selection of probiotics, the various stress factors that impact the survival capacity of probiotics during and after encapsulation, and the rational selection of appropriate protection strategies to overcome these factors and achieve the highest possible encapsulation efficiency under optimal conditions...
November 9, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29119465/probiotic-and-synbiotic-sorbets-produced-with-jussara-euterpe-edulis-pulp-evaluation-throughout-the-storage-period-and-effect-of-the-matrix-on-probiotics-exposed-to-simulated-gastrointestinal-fluids
#19
Júlia Fernanda Urbano Marinho, Marluci Palazzolli da Silva, Marcella Chalella Mazzocato, Fabrício Luiz Tulini, Carmen Sílvia Favaro-Trindade
The aims of the present study were to develop and evaluate different formulations of probiotic and synbiotic sorbets produced with jussara (Euterpe edulis) pulp, polydextrose, Lactobacillus acidophilus LA3, and Lactobacillus paracasei BGP1. The pasteurized jussara pulp presented high content of phenolic compounds, especially anthocyanins, which were not inhibitory to the probiotics used in this study. The levels of polyphenols and anthocyanins present in the sorbets were also high and kept stable for 120 days, as well as the populations of both probiotics...
November 8, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29110259/antifungal-activity-of-lactobacillus-pentosus-%C3%A5-ock-0979-in-the-presence-of-polyols-and-galactosyl-polyols
#20
Lidia Lipińska, Robert Klewicki, Michał Sójka, Radosław Bonikowski, Dorota Żyżelewicz, Krzysztof Kołodziejczyk, Elżbieta Klewicka
The antifungal activity of Lactobacillus pentosus ŁOCK 0979 depends both on the culture medium and on the fungal species. In the control medium, the strain exhibited limited antagonistic activity against indicator food-borne molds and yeasts. However, the supplementation of the bacterial culture medium with polyols (erythritol, lactitol, maltitol, mannitol, sorbitol, xylitol) or their galactosyl derivatives (gal-erythritol, gal-sorbitol, gal-xylitol) enhanced the antifungal properties of Lactobacillus pentosus ŁOCK 0979...
November 6, 2017: Probiotics and Antimicrobial Proteins
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