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Journal of Gynecologic Oncology

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https://www.readbyqxmd.com/read/29027406/comparing-prediction-models-for-lymph-node-metastasis-risk-in-endometrial-cancer-the-winner-may-not-take-it-all
#1
EDITORIAL
Sokbom Kang
No abstract text is available yet for this article.
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29027405/safety-of-fertility-sparing-surgery-for-stage-i-ovarian-clear-cell-carcinoma
#2
EDITORIAL
Jeong Yeol Park
No abstract text is available yet for this article.
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29027404/transvaginal-ultrasound-versus-magnetic-resonance-imaging-for-preoperative-assessment-of-myometrial-infiltration-in-patients-with-endometrial-cancer-a-systematic-review-and-meta-analysis
#3
Juan Luis Alcázar, Begoña Gastón, Beatriz Navarro, Rocío Salas, Juana Aranda, Stefano Guerriero
OBJECTIVE: To compare the diagnostic accuracy of transvaginal ultrasound (TVS) and magnetic resonance imaging (MRI) for detecting myometrial infiltration (MI) in endometrial carcinoma. METHODS: An extensive search of papers comparing TVS and MRI in assessing MI in endometrial cancer was performed in MEDLINE (PubMed), Web of Science, and Cochrane Database from January 1989 to January 2017. Quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29027403/survival-of-gynecological-cancers-in-turkey-where-are-we-at
#4
Murat Gultekin, Selin Dundar, Irem Kucukyildiz, Mujdegul Zayifoglu Karaca, Guledal Boztas, Semra Hatice Turan, Ezgi Hacikamiloglu, Bekir Keskinkilic
OBJECTIVE: To investigate the 5-year relative survival rates in gynecological cancers diagnosed and treated in Turkey by year 2009 and to compare the results with developed countries. METHODS: Data of patients diagnosed for ovarian, corpus uteri or cervix uteri cancer at year 2009 are collected from 9 national cancer registry centers. Date of deaths are retracted from governmental Identity Information Sharing System (KPS). In order to calculate relative survival rates, national general population mortality tables are obtained from Turkish Statistical Institute (TurkStat)...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29027402/impact-of-vaginal-cylinder-diameter-on-outcomes-following-brachytherapy-for-early-stage-endometrial-cancer
#5
Jack M Qian, John M Stahl, Melissa R Young, Elena Ratner, Shari Damast
OBJECTIVE: To examine the outcomes (tolerability, toxicity, and recurrence) of vaginal brachytherapy (VBT) among endometrial cancer (EC) patients treated with small cylinder size. METHODS: Patients with EC who received adjuvant VBT between September 2011 and December 2015 were reviewed. Patients were fitted with the largest vaginal cylinder they could comfortably accommodate, from 2.0-3.0 cm diameter. Small cylinders were defined as size 2.3 cm or less. Patient, tumor, or treatment characteristics were correlated with need for small cylinders...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29027401/identification-of-dna-methylation-associated-gene-signatures-in-endometrial-cancer-via-integrated-analysis-of-dna-methylation-and-gene-expression-systematically
#6
Chuandi Men, Hongjuan Chai, Xumin Song, Yue Li, Huawen Du, Qing Ren
OBJECTIVE: Endometrial cancer (EC) is a common gynecologic cancer worldwide. However, the pathogenesis of EC has not been epigenetically elucidated. Here, this study aims to describe the DNA methylation profile and identify favorable gene signatures highly associated with aberrant DNA methylation changes in EC. METHODS: The data regarding DNA methylation and gene expression were downloaded from The Cancer Genome Atlas (TCGA) database. Differentially methylated CpG sites (DMCs), differentially methylated regions (DMRs), and differentially expressed genes (DEGs) were identified, and the relationship between the 2 omics was further analyzed...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29027400/surgical-and-oncologic-outcomes-after-robotic-radical-hysterectomy-as-compared-to-open-radical-hysterectomy-in-the-treatment-of-early-cervical-cancer
#7
Chirag A Shah, Tiffany Beck, John B Liao, Nadia V Giannakopoulos, Dan Veljovich, Pam Paley
OBJECTIVE: The use of robotic radical hysterectomy has greatly increased in the treatment of early stage cervical cancer. We sought to compare surgical and oncologic outcomes of women undergoing robotic radical hysterectomy compared to open radical hysterectomy. METHODS: The clinic-pathologic, treatment, and recurrence data were abstracted through an Institutional Review Board-approved protocol at 2 separate large tertiary care centers in Seattle, Swedish Medical Center and the University of Washington...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29027399/early-stage-node-negative-cervical-adenocarcinoma-and-squamous-cell-carcinoma-show-similar-survival-outcomes-after-hysterectomy-a-population-based-study
#8
San Gang Wu, Jia Yuan Sun, Zhen Yu He, Qiong Hua Chen, Juan Zhou
OBJECTIVE: To investigate the clinicopathological features and outcomes between node-negative, early-stage cervical squamous cell carcinoma (SCC) and adenocarcinoma (AC) after hysterectomy. METHODS: Patients diagnosed with International Federation of Gynecology and Obstetrics (FIGO) stages I-IIA cervical SCC and AC between 1988 and 2013 were retrospectively reviewed using the Surveillance, Epidemiology, and End Results database. We used propensity score-matching to balance patient baseline characteristics...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29027398/nutritional-status-cachexia-and-anorexia-in-women-with-peritoneal-metastasis-and-intraperitoneal-chemotherapy-a-longitudinal-analysis
#9
Ziad Hilal, Günther A Rezniczek, Robert Klenke, Askin Dogan, Clemens B Tempfer
OBJECTIVE: To describe the nutritional status of women with peritoneal metastasis (PM) from recurrent ovarian, fallopian, or peritoneal cancer and to assess longitudinal variations of the cachexia-anorexia syndrome (CAS) during palliative pressurized intraperitoneal aerosol chemotherapy (PIPAC). METHODS: Nutritional assessment included body mass index (BMI), bioelectrical impedance analysis (BIA), and blood chemistry. CAS presence/absence was recorded before and during repeated cycles (1-11) of PIPAC...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29027397/comparing-treatment-outcomes-of-stage-iiib-cervical-cancer-patients-between-those-with-and-without-lower-third-of-vaginal-invasion
#10
Kanyarat Katanyoo
OBJECTIVE: To evaluate treatment outcomes between stage IIIB cervical cancer with and without lower third of vaginal invasion (LTI) in terms of response to treatment and overall survival (OS). METHODS: Matching one patient with LTI for 2 patients without LTI who had completed treatment between 1995 and 2012 were conducted by using treatment modalities (radiation therapy [RT] alone vs. concurrent chemoradiation therapy [CCRT]) and tumor histology (squamous cell carcinoma [SCC] vs...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29027396/comparison-of-three-different-risk-stratification-models-for-predicting-lymph-node-involvement-in-endometrioid-endometrial-cancer-clinically-confined-to-the-uterus
#11
Vakkas Korkmaz, Mehmet Mutlu Meydanli, Ibrahim Yalçın, Mustafa Erkan Sarı, Hanifi Sahin, Eda Kocaman, Ali Haberal, Polat Dursun, Tayfun Güngör, Ali Ayhan
OBJECTIVE: To compare the clinical validity of the Gynecologic Oncology Group-99 (GOG-99), the Mayo-modified and the European Society for Medical Oncology (ESMO)-modified criteria for predicting lymph node (LN) involvement in women with endometrioid endometrial cancer (EC) clinically confined to the uterus. METHODS: A total of 625 consecutive women who underwent comprehensive surgical staging for endometrioid EC clinically confined to the uterus were divided into low- and high-risk groups according to the GOG-99, the Mayo-modified, and the ESMO-modified criteria...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29027395/prognostic-value-of-programmed-death-ligand-1-pd-l1-expression-in-ovarian-clear-cell-carcinoma
#12
Jun Zhu, Hao Wen, Rui Bi, Yong Wu, Xiaohua Wu
OBJECTIVE: Programmed death-ligand 1 (PD-L1) was expressed in various tumors and antibodies targeting its receptor programmed cell death-1 (PD-1) are emerging cancer therapeutics. This study was designed to evaluate the expression of PD-L1 and its correlation with clinicopathologic features and clinical outcomes in ovarian clear cell carcinoma (OCCC). METHODS: The PD-L1 expression was measured by tissue-microarray-based immunohistochemistry from 122 eligible patients diagnosed with OCCC...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29027394/assessing-the-effect-of-guideline-introduction-on-clinical-practice-and-outcome-in-patients-with-endometrial-cancer-in-japan-a-project-of-the-japan-society-of-gynecologic-oncology-jsgo-guideline-evaluation-committee
#13
Shogo Shigeta, Satoru Nagase, Mikio Mikami, Masae Ikeda, Masako Shida, Isao Sakaguchi, Norichika Ushioda, Fumiaki Takahashi, Wataru Yamagami, Nobuo Yaegashi, Yasuhiro Udagawa, Hidetaka Katabuchi
OBJECTIVE: The Japan Society of Gynecologic Oncology (JSGO) published the first practice guideline for endometrial cancer in 2006. The JSGO guideline evaluation committee assessed the effect of this guideline introduction on clinical practice and patient outcome using data provided by the Japan Society of Obstetrics and Gynecology (JSOG) cancer registration system. METHODS: Data of patients with endometrial cancer registered between 2000 and 2012 were analyzed, and epidemiological and clinical trends were assessed...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29027393/down-regulated-serum-microrna-101-is-associated-with-aggressive-progression-and-poor-prognosis-of-cervical-cancer
#14
Wei Jiang, Jia Jia Pan, Ying Hui Deng, Mei Rong Liang, Li Hua Yao
OBJECTIVE: MicroRNAs (miRNAs) play a vital role in pathogenesis and progression of many cancers, including cervical cancer. However, importance of serum level of miR-101 in cervical cancer has rarely been studied. In the present study, clinical significance and prognostic value of serum miR-101 for cervical cancer was investigated. METHODS: Association between miR-101 level in cervical cancer tissues and prognosis of patients was analyzed by using data retrieved from The Cancer Genome Atlas (TCGA) database, which was followed with our clinical study in which miR-101 serum level comparison between cervical cancer patients and healthy controls was conducted by real-time quantitative polymerase chain reaction (PCR)...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/28758379/external-validation-of-chemotherapy-response-score-system-for-histopathological-assessment-of-tumor-regression-after-neoadjuvant-chemotherapy-in-tubo-ovarian-high-grade-serous-carcinoma
#15
Jung Yun Lee, Young Shin Chung, Kiyong Na, Hye Min Kim, Cheol Keun Park, Eun Ji Nam, Sunghoon Kim, Sang Wun Kim, Young Tae Kim, Hyun Soo Kim
OBJECTIVE: The chemotherapy response score (CRS) system based on histopathological examination has been recently proposed for tubo-ovarian high-grade serous carcinoma (HGSC) to assess response to neoadjuvant chemotherapy (NAC). This study was aimed at validating the CRS system in an external cohort of tubo-ovarian HGSC patients. METHODS: This study included 110 tubo-ovarian HGSC patients who underwent NAC followed by interval debulking surgery. The 3-tiered CRS of the omental and adnexal tissue sections was determined by 3 independent pathologists...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/28758378/fear-of-cancer-recurrence-and-its-predictors-among-cervical-cancer-survivors
#16
Jitti Hanprasertpong, Alan Geater, Ingporn Jiamset, Laaong Padungkul, Phongchawee Hirunkajonpan, Nartya Songhong
OBJECTIVE: To identify the characteristics of fear of cancer recurrence (FCR) in cervical cancer survivors (CCSs) and investigate the relationship of FCR with demographic and medical characteristics, level of quality of life (QOL), and psychological distress. We also aimed to determine the predictors of FCR. METHODS: The short version of the Fear of Progression Questionnaire (FoP-Q-SF), the Hospital Anxiety and Depression Scale (HADS), and the Functional Assessment of Cancer Therapy-Cervical (FACT-Cx) questionnaire were administered to 699 CCSs who had complete treatment at Songklanagarind Hospital between 2006 and 2016...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/28758377/could-fertility-sparing-surgery-be-considered-for-women-with-early-stage-ovarian-clear-cell-carcinoma
#17
Dimitrios Nasioudis, Eloise Chapman-Davis, Melissa K Frey, Steven S Witkin, Kevin Holcomb
OBJECTIVE: The aim of the present retrospective population-based study was to investigate the oncologic impact of uterine and ovarian preservation (OP) in premenopausal women with stage IA or IC ovarian clear cell carcinoma (OCCC). METHODS: The National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) database was accessed and a cohort of surgically-staged premenopausal women (age <50 years) diagnosed with unilateral stage IA or IC OCCC was drawn...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/28758380/highlights-from-the-gynecologic-oncology-track-at-the-2017-annual-meeting-of-the-american-society-of-clinical-oncology
#18
Juliet E Wolford, Krishnansu S Tewari
No abstract text is available yet for this article.
September 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/28657231/does-a-robotic-surgery-approach-offer-optimal-ergonomics-to-gynecologic-surgeons-a-comprehensive-ergonomics-survey-study-in-gynecologic-robotic-surgery
#19
Mija Ruth Lee, Gyusung Isaiah Lee
OBJECTIVE: To better understand the ergonomics associated with robotic surgery including physical discomfort and symptoms, factors influencing symptom reporting, and robotic surgery systems components recommended to be improved. METHODS: The anonymous survey included 20 questions regarding demographics, systems, ergonomics, and physical symptoms and was completed by experienced robotic surgeons online through American Association of Gynecologic Laparoscopists (AAGL) and Society of Robotic Surgery (SRS)...
September 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/28657230/malignant-transformation-of-ovarian-mature-cystic-teratoma-into-squamous-cell-carcinoma-a-taiwanese-gynecologic-oncology-group-tgog-study
#20
An Jen Chiang, Min Yu Chen, Chia Sui Weng, Hao Lin, Chien Hsing Lu, Peng Hui Wang, Yu Fang Huang, Ying Cheng Chiang, Mu Hsien Yu, Chih Long Chang
OBJECTIVE: The malignant transformation (MT) of ovarian mature cystic teratoma (MCT) to squamous cell carcinoma (SCC) is very rare. This study analyzed cases from multiple medical centers in Taiwan to investigate the clinicopathologic characteristics, treatment, and prognostic factors of this disease and reviewed related literature. METHODS: Pathological reports of 16,001 patients with primary ovarian cancer who were treated at Taiwan medical centers from 1990 to 2011 were reviewed...
September 2017: Journal of Gynecologic Oncology
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