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Open Ophthalmology Journal

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https://www.readbyqxmd.com/read/27843513/bilateral-choroidal-metastases-from-endobronchial-carcinoid-treated-with-somatostatin-analogues
#1
Deborah De Bruyn, Jan Lamont, Erik Vanderstraeten, Simon Van Belle, Elise Platteau, Julie De Zaeytijd, Kristien P Hoornaert
OBJECTIVE: To describe a patient with bilateral multifocal choroidal metastases from an endobronchial carcinoid treated with a somatostatin analogue. METHOD: A 60-year-old woman presenting with photopsia in the left eye underwent an extensive ophthalmic examination, including fluorescein angiography, OCT and ultrasound. RESULTS: Fundoscopy revealed a small retinal tear in the left eye, for which she received laser treatment. In addition, choroidal masses were detected in both eyes...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27651849/characteristics-of-sympathetic-ophthalmia-in-a-single-international-center
#2
Pablo Jose Guzman-Salas, Juan Carlos Serna-Ojeda, Ethel Beatriz Guinto-Arcos, Miguel Pedroza-Seres
AIM: To report the main features of sympathetic ophthalmia in a referral ophthalmology center. METHODS: Retrospective clinical study. We reviewed clinical records of patients with diagnosis of sympathetic ophthalmia attending the Uveitis Department from 2007 to 2013. Patients were selected by clinical criteria. Descriptive statistics were used to assess variables. RESULTS: Twenty patients were included for analysis, 13 males and 7 females...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27347250/ocular-tolerability-of-preservative-free-tafluprost-and-latanoprost-in-vitro-and-in-vivo-comparative-study
#3
Yoshihiko Esaki, Atsushi Shimazaki, Pertti Pellinen
OBJECTIVE: Detrimental effects of the preserved prostaglandin analogs (PGAs) have been thoroughly documented in the published literature. The current work studied two preservative-free (PF) prostaglandin eye drops: PF tafluprost and PF latanoprost. The aim of the study was to compare these two PF formulations in vitro for viability of the human corneal epithelial (HCE-T) cells and in vivo for ocular tolerability of the rabbit eye. METHOD: Viability of the HCE-T cells was measured by the MTS assay...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27347249/risk-factors-for-primary-open-angle-glaucoma-poag-progression-a-study-ruled-in-torino
#4
A G Actis, E Versino, B Brogliatti, T Rolle
PURPOSE: Aim of this retrospective, observational study is to describe features of a population sample, affected by primary open angle glaucoma (POAG) in order to evaluate damage progression on the basis of the emerged individual risk factors. METHODS: We included 190 caucasian patients (377 eyes), evaluating relationship between individual risk factors (explicative variables) and MD (Mean Deviation) of standard automated perimetry. We also considered the dependent variable NFI (Neural Fiber Index) of GDx scanning laser polarimetry...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27347248/lithium-induced-downbeat-nystagmus-and-horizontal-gaze-palsy
#5
Jesper Skovlund Jørgensen, Lisbeth Landschoff Lassen, Marianne Wegener
We report a case of lithium-induced downbeat nystagmus and horizontal gaze palsy in a 62-year-old woman who was treated for a bipolar affective disorder with lithium carbonate for one month. At presentation serum lithium was within therapeutic range. No alternative causes of the ocular motility disturbances were found, and the patient improved significantly as lithium carbonate was discontinued.
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27347247/evaluation-of-a-public-child-eye-health-tertiary-facility-for-pediatric-cataract-in-southern-nigeria-i-visual-acuity-outcome
#6
Roseline E Duke, Adedayo Adio, Sidney K Oparah, Friday Odey, Okon A Eyo
PURPOSE: A retrospective study of the outcome of congenital and developmental cataract surgery was conducted in a public child eye health tertiary facility in children <16 years of age in Southern Nigeria, as part of an evaluation. MATERIALS AND METHOD: Manual Small Incision Cataract Surgery with or without anterior vitrectomy was performed. The outcome measures were visual acuity (VA) and change (gain) in visual acuity. The age of the child at onset, duration of delay in presentation, ocular co-morbidity, non ocular co-morbidity, gender, and pre operative visual acuity were matched with postoperative visual acuity...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27347246/long-term-clinical-and-visual-outcomes-of-retrofixated-iris-claw-lenses-implantation-in-complicated-cases
#7
Sri Ganesh, Sheetal Brar, Kirti Relekar
AIMS: To evaluate the visual outcomes and complications after implantation of retrofixated iris claw (RFIC) lens in various challenging situations. SETTINGS AND DESIGN: Retrospective, single centre, 8 year clinical audit. MATERIALS AND METHODS: A retrospective analysis of cases who underwent RFIC lens implantation alone (group 1) or in combination with vitreoretinal (VR), corneal or glaucoma procedures (group 2) was performed. The main outcomes evaluated were corrected distant visual acuity (CDVA) and postoperative complications...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27073587/efficacy-and-safety-of-switching-latanoprost-monotherapy-to-bimatoprost-monotherapy-or-combination-of-brinzolamide-and-latanoprost
#8
Mitsuhiro Imasawa, Joji Tanabe, Fumiko Kashiwagi, Kenji Kashiwagi
PURPOSE: To prospectively assess the efficacy and safety of switching to bimatoprost monotherapy or brinzolamide and latanoprost combination therapy in patients who had been receiving latanoprost monotherapy. METHODS: A prospective, open-label study was conducted. Patients with primary open-angle glaucoma or ocular hypertension who had been receiving latanoprost monotherapy for three months or more were enrolled. Bimatoprost was substituted for latanoprost in one eye (BIM group), and brinzolamide was added to the latanoprost in the other eye (BRZ group) simultaneously...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27053973/serial-intravitreal-bevacizumab-injections-slow-the-progression-of-radiation-maculopathy-following-iodine-125-plaque-radiotherapy
#9
Andrew W Stacey, Hakan Demirci
BACKGROUND AND OBJECTIVE: To assess the outcomes of intravitreal bevacizumab injection in the management of radiation maculopathy secondary to plaque radiotherapy, and to identify optimal treatment strategies. STUDY DESIGN: A retrospective review of all choroidal melanoma patients at one referral center who were treated with plaque radiotherapy, subsequently developed radiation maculopathy, and received intravitreal bevacizumab. RESULTS: A total of 31 patients were identified...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27014390/managing-primary-angle-closure-glaucoma-the-role-of-lens-extraction-in-this-era
#10
Nafees Baig, Ka-Wai Kam, Clement C Y Tham
Trabeculectomy has been the gold standard in reducing intraocular pressure (IOP) in glaucoma patients, no matter it is angle closure or open angle glaucoma. However in primary angle closure glaucoma, no matter the lens is cataractous or not, it is likely to be pathological, this thicker than usual lens, with or without a more anterior position, is often regarded as a strong contributing factor to angle closure. Lens extraction, no matter it is cataractous or clear, can theoretically eliminate this anatomical predisposing factor of angle closure, and thus IOP can be reduced...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27014389/current-and-future-techniques-in-wound-healing-modulation-after-glaucoma-filtering-surgeries
#11
Masoumeh B Masoumpour, M Hossein Nowroozzadeh, M Reza Razeghinejad
Filtering surgeries are frequently used for controlling intraocular pressure in glaucoma patients. The long-term success of operation is intimately influenced by the process of wound healing at the site of surgery. Indeed, if has not been anticipated and managed accordingly, filtering surgery in high-risk patients could end up in bleb failure. Several strategies have been developed so far to overcome excessive scarring after filtering surgery. The principal step involves meticulous tissue handling and modification of surgical technique, which can minimize the severity of wound healing response at the first place...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27014388/current-and-future-of-laser-therapy-in-the-management-of-glaucoma
#12
Feyzahan Ekici, Michael Waisbourd, L Jay Katz
There has been tremendous progress in the past decades in the utilization of lasers for treating patients with glaucoma. This article reviews the use of lasers in different areas of glaucoma, including the shift from argon laser trabeculoplasty (ALT) to selective laser trabeculoplasty (SLT), laser trabeculoplasty as an initial treatment for glaucoma, new laser trabeculoplasty procedures under investigation, and other recent laser treatment modalities such as endoscopic cyclophotocoagulation and laser-assisted deep sclerectomy...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27014387/detecting-iop-fluctuations-in-glaucoma-patients
#13
Brenda Nuyen, Kaweh Mansouri
Lowering intraocular pressure (IOP) remains the guiding principle of glaucoma management. Although IOP is the only treatable risk factor, its 24-hour behavior is poorly understood. Current glaucoma management usually relies on single IOP measurements during clinic hours, even though IOP is a dynamic parameter with rhythms dependent on individual patients. It has further been shown that most glaucoma patients have their highest IOP measurements outside clinic hours. The fact that these IOP peaks go largely undetected may explain why certain patients progress in their disease despite treatment...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27014386/intra-ocular-pressure-measurement-in-a-patient-with-a-thin-thick-or-abnormal-cornea
#14
Colin I Clement, Douglas G A Parker, Ivan Goldberg
Accurate measurement of intra-ocular pressure is a fundamental component of the ocular examination. The most common method of measuring IOP is by Goldmann applanation tonometry, the accuracy of which is influenced by the thickness and biomechanical properties of the cornea. Algorithms devised to correct for corneal thickness to estimate IOP oversimplify the effects of corneal biomechanics. The viscous and elastic properties of the cornea influence IOP measurements in unpredictable ways, a finding borne out in studies of patients with inherently abnormal and surgically altered corneal biomechanics...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27014385/editorial-update-on-glaucoma-diagnosis-and-management
#15
M Reza Razeghinejad, M Hossein Nowroozzadeh
No abstract text is available yet for this article.
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27014384/a-case-of-anterior-chamber-cholesterolosis-due-to-coats-disease-and-a-review-of-reported-cases
#16
Andrew W Stacey, Melissa Borri, Sonia De Francesco, Angela S Antenore, Felice Menicacci, Theodora Hadjistilianou
PURPOSE: To present the case of an 18 month old boy with Coats' disease who was found to have anterior chamber cholesterolosis. METHODS: Case presentation and review of reported cases. RESULTS: An 18 month old boy presented with unilateral stage 3B Coats' disease without other clinical findings. Two weeks after presentation he returned with xanthocoria due to anterior chamber cholesterolosis. He subsequently developed hyphema, neovascular glaucoma, and was enucleated...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27014383/coats-disease-very-long-term-outcome-after-early-stage-conventional-treatment
#17
Salvatore Perrone, Alberto Rossetti, Patrick Sportiello, Pierfrancesco Mirabelli, Pierangela Cimatti, Daniele Doro
PURPOSE: To report on the outcome of conventional therapy in patients with Coats' disease. METHODS: Retrospective analysis of the charts of thirteen patients with Coats' disease. RESULTS: Mean age of 9 male (70%) and 4 female (30%) patients was 17.7 (range, 5-33) years; one female had bilateral disease. Eleven eyes with retinal telangiectasia and exudation were treated with argon laser photocoagulation alone or photocoagulation associated with cryotherapy; the mean follow up was 32...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27014382/retinopathy-of-prematurity-in-neonates-and-its-risk-factors-a-seven-year-study-in-northern-iran
#18
Seyed Ahmad Rasoulinejad, Mohammad Montazeri
PURPOSE: An important cause of avoidable childhood blindness is retinopathy of prematurity (ROP) in countries with high human development index and also in some emerging economies countries. To date, no research have been conducted on analyzing data of ROP prevalence in Babol, and this is the first research performed on ROP in this area. METHODS: All VLBW babies who referred to Babol ophthalmology center over the seven years, from February 2007 to December 2013 were enrolled in this descriptive cross-sectional research...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27014381/the-effect-of-intravitreal-azithromycin-on-the-albino-newborn-rabbit-retina
#19
Duygu Cam, Ali Osman Saatci, Serap Cilaker Micili, Bekir Ugur Ergur, Revan Yildirim Karabag, Ismet Durak, Ayse Tulin Berk
PURPOSE: To evaluate the effect of intravitreal azithromycin on the retina in a newborn rabbit model. METHODS: Twelve, two-week old New Zealand albino rabbits were divided into two groups (six in each). The right eyes of six rabbits received 0.75 mg (0.05 mL) azithromycin and the right eyes of the remaining six rabbits 1.5 mg (0.1 mL) azithromycin intravitreally. Left eyes were served as the control and received the same volume of saline. All eyes were enucleated at the third postinjection week...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27014380/ocular-neurologic-and-systemic-findings-of-the-cases-with-optic-nerve-hypoplasia
#20
Eyyup Karahan, Ayse Tulin Berk
AIM: To describe the associated ocular, neurologic, and systemic findings in a population of children with optic nerve hypoplasia (ONH) and to evaluate the relationship between ocular signs and neurologic findings. METHOD: A retrospective chart review of 53 patients with the diagnosis of ONH seen between December 1998 and September 2012 was performed. All neurodevelopmental anomalies, neuroradiologic findings, endocrinologic and systemic findings were recorded. Poor vision was defined as the visual acuity poorer than logMAR 1...
2016: Open Ophthalmology Journal
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