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Open Ophthalmology Journal

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https://www.readbyqxmd.com/read/28761569/efficacy-and-safety-of-switching-from-prostaglandin-analog-therapy-to-prostaglandin-timolol-fixed-combination-or-prostaglandin-brimonidine-therapy
#1
Kenji Inoue, Mieko Masumoto, Kyoko Ishida, Goji Tomita
BACKGROUND: To compare the safety and efficacy between switching to prostaglandin/timolol fixed combination eye drops (PG/timolol FCs) and adding brimonidine to PG analogue monotherapy. METHODS: Eyes of 53 patients with primary open-angle glaucoma or ocular hypertension who were receiving PG analogue monotherapy were included. Participants were randomly divided into two treatment groups: one was prescribed PG/timolol FCs (switched group), and for the other, 0.1% brimonidine was added to the PG analogue (added group)...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28761568/the-effects-of-ramadan-fasting-on-anterior-segment-parameters-visual-acuity-and-intraocular-pressures-of-the-eye
#2
Ozlem Barut Selver, Melis Palamar, Kevser Gerceker, Sait Egrilmez, Ayse Yagci
OBJECTIVE: It is aimed to determine whether fasting during Ramadan has any significant effect on anterior chamber parameters, visual acuity and intraocular pressures. METHODS: 31 fasting (Group 1) and 30 non-fasting healthy volunteers (Group 2) were enrolled. All cases underwent an ophthalmological examination and anterior segment parameter evaluation (central corneal thickness (CCT), anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), pupil size) with Pentacam before and after the breaking of the Ramadan fast in Group 1, before and after dinner in Group 2...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28761567/using-an-image-fusion-methodology-to-improve-efficiency-and-traceability-of-posterior-pole-vessel-analysis-by-roptool
#3
Sasapin G Prakalapakorn, Laura A Vickers, Rolando Estrada, Sharon F Freedman, Carlo Tomasi, Sina Farsiu, David K Wallace
BACKGROUND: The diagnosis of plus disease in retinopathy of prematurity (ROP) largely determines the need for treatment; however, this diagnosis is subjective. To make the diagnosis of plus disease more objective, semi-automated computer programs (e.g. ROPtool) have been created to quantify vascular dilation and tortuosity. ROPtool can accurately analyze blood vessels only in images with very good quality, but many still images captured by indirect ophthalmoscopy have insufficient image quality for ROPtool analysis...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28761566/many-faces-of-renin-angiotensin-system-focus-on-eye
#4
REVIEW
Mervi Holappa, Heikki Vapaatalo, Anu Vaajanen
The renin-angiotensin system (RAS), that is known for its role in the regulation of blood pressure as well as in fluid and electrolyte homeostasis, comprises dozens of angiotensin peptides and peptidases and at least six receptors. Six central components constitute the two main axes of the RAS cascade. Angiotensin (1-7), an angiotensin converting enzyme 2 and Mas receptor axis (ACE2-Ang(1-7)-MasR) counterbalances the harmful effects of the angiotensin II, angiotensin converting enzyme 1 and angiotensin II type 1 receptor axis (ACE1-AngII-AT1R) Whereas systemic RAS is an important factor in blood pressure regulation, tissue-specific regulatory system, responsible for long term regional changes, that has been found in various organs...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28761565/first-reported-case-of-donor-related-candida-endophthalmitis-after-descemet-membrane-endothelial-keratoplasty
#5
Matthew Thompson, David Carli
PURPOSE: To report the first case of Candida donor to host transmission following descemet membrane endothelial keratoplasty (DMEK). METHODS: A retrospective case report. RESULTS: A patient underwent uneventful DMEK. Following surgery the donor rim was culture positive for Candida. The patient developed fungal endophthalmitis that was treated medically with multiple injections of voriconazole and amphotericin. Medical treatment was unable to clear the infection and removal of the donor material was required...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28660005/histological-findings-in-the-trabecular-meshwork-of-a-patient-with-atopic-glaucoma
#6
Satoru Kase, Shiki Chin, Teruhiko Hamanaka, Yasuhiro Shinmei, Takeshi Ohguchi, Riki Kijima, Akira Matsuda, Susumu Ishida
PURPOSE: The aim of this study was to report a case of atopic dermatitis showing elevated intraocular pressure (IOP) beyond the baseline levels followed by a modified 360-degree suture trabeculotomy, and to analyze the histological findings in the trabecular meshwork. METHODS: A 40-year-old male suffered from blurred vision in the right eye (OD). He had a medical history of severe atopic dermatitis and intraocular lens implantation OU due to atopic cataract. At the initial presentation, the visual acuity was 0...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28603574/central-retinal-vein-occlusion-in-younger-swedish-adults-case-reports-and-review-of-the-literature
#7
Elisabeth Wittström
PURPOSE: To investigate associated systemic diseases, other conditions, visual outcome, ocular complications and treatment in Swedish patients younger than 50 years with central retinal vein occlusion (CRVO) and reviewing the literature. METHODS: Twenty-two patients with CRVO, younger than 50 years, were examined with full-field electroretinography (ERG) within 3 months after a thrombotic event, or were periodically examined and were observed for at least 6 months...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28584563/the-relationship-of-amount-of-resection-and-time-for-recovery-of-bell-s-phenomenon-after-levator-resection-in-congenital-ptosis
#8
Ruchi Goel, Divya Kishore, Smriti Nagpal, Sparshi Jain, Tushar Agarwal
BACKGROUND: Recovery of Bell`s phenomenon after levator resection is unpredicatable. Delayed recovery can result in vision threatening corneal complications. AIM: To study the variability of Bell's phenomenon and time taken for its recovery following levator resection for blepharoptosis and to correlate it with the amount of resection. METHODS: A prospective observational study was conducted on 32 eyes of 32 patients diagnosed as unilateral simple congenital blepharoptosis who underwent levator resection at a tertiary care center between July 2013 and May 2015...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28567166/the-effect-of-vitamin-e-on-oxidative-stress-indicated-by-serum-malondialdehyde-in-insulin-dependent-type-2-diabetes-mellitus-patients-with-retinopathy
#9
Irini P Chatziralli, George Theodossiadis, Prodromos Dimitriadis, Michail Charalambidis, Antonios Agorastos, Zisis Migkos, Nikolaos Platogiannis, Marilita M Moschos, Panagiotis Theodossiadis, Petros Keryttopoulos
BACKGROUND: Several studies have focused on oxidative stress on diabetes mellitus (DM). Our purpose was to investigate the impact of oxidative stress on progression of diabetic retinopathy (DR) in insulin-dependent type 2 DM patients, measuring serum malondialdehyde (MDA), as well as to examine the effect of vitamin E on DR progression in the above-mentioned patients. METHODS: Participants in the study were 282 insulin-dependent type 2 DM patients with DR. All participants underwent a thorough ophthalmological examination, so as to grade DR, along with serum MDA measurement...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28567165/letter-to-the-editor-corneoscleral-melt-50-years-after-excision-of-pterygium
#10
Aki Kondo, Tatsuya Mimura, Mari Goto, Yuko Kamei, Saito Yusuke, Hiroko Okuma, Masao Matsubara
PURPOSE: To report a case of corneoscleral melt that occurred 50 years after resection of pterygium with postoperative administration of mitomycin C (MMC). RESULTS: A 93-year-old woman developed acute corneal perforation and scleral melt in her left eye at 50 years after pterygium surgery with postoperative topical MMC. She underwent limbal transplantation. The anterior chamber reformed postoperatively and her intraocular pressure was normal. At 12 months after transplantation, best-corrected visual acuity was 20/500 and the graft-host junction was well apposed...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28567164/pars-plana-vitrectomy-with-internal-limiting-membrane-peeling-for-nontractional-diabetic-macular-edema
#11
Jan Niklas Ulrich
BACKGROUND: Diabetes mellitus remains the leading cause of blindness among working age Americans with diabetic macular edema being the most common cause for moderate and severe vision loss. OBJECTIVE: To investigate the anatomical and visual benefits of pars plana vitrectomy with inner limiting membrane peeling in patients with nontractional diabetic macular edema as well as correlation of integrity of outer retinal layers on spectral domain optical coherence tomography to visual outcomes...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28553426/characteristics-of-anterior-lens-opacities-in-children
#12
Lena Dixit, Michael Puente, Kimberly G Yen
BACKGROUND: Anterior lens opacities (ALO) are found in 3-14% of pediatric patients with cataracts. No clear guidelines exist in the management and treatment of these cataracts. OBJECTIVE: To evaluate pediatric patients with anterior lens opacities and assess rate of amblyopia and need for surgery over time. METHODS: A retrospective chart review was performed on patients with unilateral and bilateral anterior lens opacities (ALOs) seen between January 2008 and December 2014...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28553425/treatment-of-symptomatic-vitreomacular-adhesion-with-expansile-sulfur-hexafluoride-sf6-gas
#13
Dominic M Buzzacco, Sugat S Patel
BACKGROUND: To evaluate intravitreal injection of expansile sulfur hexafluoride (SF6) as a low cost and effective treatment for symptomatic vitreomacular adhesion (sVMA). METHODS: Retrospective analysis of all patients with sVMA treated with pneumatic vitreolysis using SF6 gas presenting to a clinical practice from January 2005 and June 2013. RESULTS: Six cases were included in the study. Five patients (83%) experienced complete resolution of the vitreomacular adhesion...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28553424/bilateral-idiopathic-sclerochoroidal-calcifications
#14
Venkatesh L Brahma, Sumit P Shah, Nauman A Chaudhry, Jonathan L Prenner
BACKGROUND: Sclerochoroidal calcification (SCC) is a rare and benign condition found mostly in middle-aged and elderly Caucasian men, characterized by multiple yellow-white lesions seen most commonly in the temporal regions of the fundus. While they may be concerning for benign tumors, primary neoplasias or metastases, SCCs most commonly present as asymptomatic findings during routine ophthalmologic testing and have a very good prognosis as they rarely cause visual deficits. OBJECTIVE: To report and describe the findings in a case of bilateral idiopathic sclerochoroidal calcifications...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28553423/corneal-refractive-procedures-for-the-treatment-of-presbyopia
#15
REVIEW
Kareem Moussa, Naz Jehangir, Tova Mannis, Wai L Wong, Majid Moshirfar
PURPOSE: Refractive surgery has been in use for a long time and is evolving at a fast pace with several new corneal procedures being used for the correction of presbyopia. The purpose of this article is to give a comprehensive review of the literature to evaluate the outcome and success of different corneal refractive surgical procedures in presbyopic patients. METHODS: We performed a comprehensive search on PubMed to identify published reports of the various procedures utilized in the past and present to correct presbyopia...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28400890/comparison-of-ethnic-specific-databases-in-heidelberg-retina-tomography-3-to-discriminate-between-early-glaucoma-and-normal-chinese-eyes
#16
Xiu Ling Tan, Sae Cheong Yap, Xiang Li, Leonard W Yip
PURPOSE: To compare the diagnostic accuracy of the 3 race-specific normative databases in Heidelberg Retina Tomography (HRT)-3, in differentiating between early glaucomatous and healthy normal Chinese eyes. METHOD: 52 healthy volunteers and 25 glaucoma patients were recruited for this prospective cross-sectional study. All underwent standardized interviews, ophthalmic examination, perimetry and HRT optic disc imaging. Area under the curve (AUC) receiver operating characteristics, sensitivity and specificity were derived to assess the discriminating abilities of the 3 normative databases, for both Moorfields Regression Analysis (MRA) and Glaucoma Probability Score (GPS)...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28400889/evaluation-of-ocular-surface-disease-in-asian-patients-with-primary-angle-closure
#17
Tan Ee Ling, Khairuddin Othman, Ong Poh Yan, Rasdi Abdul Rashid, Cheong Min Tet, Azhany Yaakob, Liza-Sharmini Ahmad Tajudin
OBJECTIVE: To evaluate the incidence of ocular surface disease (OSD) and to determine the effects of topical pressure-lowering drugs on ocular surface disease in primary angle closure patients. METHODS: This was a cross-sectional comparative study comparing primary angle closure glaucoma (PACG) patients (Group A) with primary angle closure and primary angle closure suspect (Group B). Group A was treated with topical pressure-lowering drugs; Group B was not. Data on ocular diagnosis and details of treatment were obtained from medical records...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28400888/macular-evaluation-w%C3%A4-th-spectral-domain-type-optic-coherence-tomography-in-eyes-with-acute-nonarteritic-ischemic-optic-neuropathy-at-the-presentation-visit
#18
Oya Donmez, Gamze Kocaoglu, Aylin Yaman, Meltem Soylev Bajin, Ali Osman Saatci
PURPOSE: To evaluate the macula with spectral domain type optic coherence tomography (OCT) in eyes with acute nonarteritic anterior ischemic optic neuropathy (NAION) at the presentation visit. METHODS: Medical charts of the 133 patients who received the diagnosis of acute NAION between January 2008 and July 2014 at the Neuro-ophthalmology unit of Dokuz Eylul University were reviewed retrospectively. Sixtythree patients within 30 days of symptom onset with available baseline spectral domain type macular OCT were included in this study...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28400887/antibiotic-prophylaxis-in-orbital-fractures
#19
Benjamin Reiss, Lamise Rajjoub, Tamer Mansour, Tony Chen, Aisha Mumtaz
PURPOSE: To determine whether prophylactic antibiotic use in patients with orbital fracture prevent orbital infection. DESIGN: Retrospective cohort study. PARTICIPANTS: All patients diagnosed with orbital fracture between January 1, 2008 and March 1, 2014 at The George Washington University Hospital and Clinics. MAIN OUTCOME MEASURES: Development of orbital infection. RESULTS: One hundred seventy-two patients with orbital fracture met our inclusion and exclusion criteria...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28400886/corneal-toxicity-following-exposure-to-asclepias-tuberosa
#20
Lauge Hjorth Mikkelsen, Hassan Hamoudi, Cigdem Altuntas Gül, Steffen Heegaard
PURPOSE: To present a case of corneal toxicity following exposure to milky plant latex from Asclepias tuberosa. METHODS: A 70-year-old female presented with blurred vision and pain in her left eye after handling an Ascepias tuberosa. Clinical examination revealed a corneal stromal oedema with small epithelial defects. The corneal endothelium was intact and folds in Descemets membrane were observed. The oedema was treated with chloramphenicol, dexamethasone and scopolamine...
2017: Open Ophthalmology Journal
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