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Open Ophthalmology Journal

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https://www.readbyqxmd.com/read/28400890/comparison-of-ethnic-specific-databases-in-heidelberg-retina-tomography-3-to-discriminate-between-early-glaucoma-and-normal-chinese-eyes
#1
Xiu Ling Tan, Sae Cheong Yap, Xiang Li, Leonard W Yip
PURPOSE: To compare the diagnostic accuracy of the 3 race-specific normative databases in Heidelberg Retina Tomography (HRT)-3, in differentiating between early glaucomatous and healthy normal Chinese eyes. METHOD: 52 healthy volunteers and 25 glaucoma patients were recruited for this prospective cross-sectional study. All underwent standardized interviews, ophthalmic examination, perimetry and HRT optic disc imaging. Area under the curve (AUC) receiver operating characteristics, sensitivity and specificity were derived to assess the discriminating abilities of the 3 normative databases, for both Moorfields Regression Analysis (MRA) and Glaucoma Probability Score (GPS)...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28400889/evaluation-of-ocular-surface-disease-in-asian-patients-with-primary-angle-closure
#2
Tan Ee Ling, Khairuddin Othman, Ong Poh Yan, Rasdi Abdul Rashid, Cheong Min Tet, Azhany Yaakob, Liza-Sharmini Ahmad Tajudin
OBJECTIVE: To evaluate the incidence of ocular surface disease (OSD) and to determine the effects of topical pressure-lowering drugs on ocular surface disease in primary angle closure patients. METHODS: This was a cross-sectional comparative study comparing primary angle closure glaucoma (PACG) patients (Group A) with primary angle closure and primary angle closure suspect (Group B). Group A was treated with topical pressure-lowering drugs; Group B was not. Data on ocular diagnosis and details of treatment were obtained from medical records...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28400888/macular-evaluation-w%C3%A4-th-spectral-domain-type-optic-coherence-tomography-in-eyes-with-acute-nonarteritic-ischemic-optic-neuropathy-at-the-presentation-visit
#3
Oya Donmez, Gamze Kocaoglu, Aylin Yaman, Meltem Soylev Bajin, Ali Osman Saatci
PURPOSE: To evaluate the macula with spectral domain type optic coherence tomography (OCT) in eyes with acute nonarteritic anterior ischemic optic neuropathy (NAION) at the presentation visit. METHODS: Medical charts of the 133 patients who received the diagnosis of acute NAION between January 2008 and July 2014 at the Neuro-ophthalmology unit of Dokuz Eylul University were reviewed retrospectively. Sixtythree patients within 30 days of symptom onset with available baseline spectral domain type macular OCT were included in this study...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28400887/antibiotic-prophylaxis-in-orbital-fractures
#4
Benjamin Reiss, Lamise Rajjoub, Tamer Mansour, Tony Chen, Aisha Mumtaz
PURPOSE: To determine whether prophylactic antibiotic use in patients with orbital fracture prevent orbital infection. DESIGN: Retrospective cohort study. PARTICIPANTS: All patients diagnosed with orbital fracture between January 1, 2008 and March 1, 2014 at The George Washington University Hospital and Clinics. MAIN OUTCOME MEASURES: Development of orbital infection. RESULTS: One hundred seventy-two patients with orbital fracture met our inclusion and exclusion criteria...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28400886/corneal-toxicity-following-exposure-to-asclepias-tuberosa
#5
Lauge Hjorth Mikkelsen, Hassan Hamoudi, Cigdem Altuntas Gül, Steffen Heegaard
PURPOSE: To present a case of corneal toxicity following exposure to milky plant latex from Asclepias tuberosa. METHODS: A 70-year-old female presented with blurred vision and pain in her left eye after handling an Ascepias tuberosa. Clinical examination revealed a corneal stromal oedema with small epithelial defects. The corneal endothelium was intact and folds in Descemets membrane were observed. The oedema was treated with chloramphenicol, dexamethasone and scopolamine...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28484581/masquerading-orbital-sarcoidosis-with-isolated-extraocular-muscle-involvement
#6
Jane S Kim, Richard L Scawn, Bradford W Lee, Jonathan H Lin, Bobby S Korn, Don O Kikkawa
Two patients, previously diagnosed and treated for euthyroid, autoantibody-negative thyroid eye disease, presented with active orbitopathy. An atypical disease course and presentation prompted orbital biopsy. Extraocular muscle histopathology demonstrated noncaseating granulomatous inflammation consistent with presumed orbital sarcoidosis involving multiple extraocular muscles, including the inferior oblique in one of the cases. These two cases emphasize the importance of a broad differential diagnosis and the utility of an orbital biopsy in the context of an unusual disease presentation or poor treatment response...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27843513/bilateral-choroidal-metastases-from-endobronchial-carcinoid-treated-with-somatostatin-analogues
#7
Deborah De Bruyn, Jan Lamont, Erik Vanderstraeten, Simon Van Belle, Elise Platteau, Julie De Zaeytijd, Kristien P Hoornaert
OBJECTIVE: To describe a patient with bilateral multifocal choroidal metastases from an endobronchial carcinoid treated with a somatostatin analogue. METHOD: A 60-year-old woman presenting with photopsia in the left eye underwent an extensive ophthalmic examination, including fluorescein angiography, OCT and ultrasound. RESULTS: Fundoscopy revealed a small retinal tear in the left eye, for which she received laser treatment. In addition, choroidal masses were detected in both eyes...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27651849/characteristics-of-sympathetic-ophthalmia-in-a-single-international-center
#8
Pablo Jose Guzman-Salas, Juan Carlos Serna-Ojeda, Ethel Beatriz Guinto-Arcos, Miguel Pedroza-Seres
AIM: To report the main features of sympathetic ophthalmia in a referral ophthalmology center. METHODS: Retrospective clinical study. We reviewed clinical records of patients with diagnosis of sympathetic ophthalmia attending the Uveitis Department from 2007 to 2013. Patients were selected by clinical criteria. Descriptive statistics were used to assess variables. RESULTS: Twenty patients were included for analysis, 13 males and 7 females...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27347250/ocular-tolerability-of-preservative-free-tafluprost-and-latanoprost-in-vitro-and-in-vivo-comparative-study
#9
Yoshihiko Esaki, Atsushi Shimazaki, Pertti Pellinen
OBJECTIVE: Detrimental effects of the preserved prostaglandin analogs (PGAs) have been thoroughly documented in the published literature. The current work studied two preservative-free (PF) prostaglandin eye drops: PF tafluprost and PF latanoprost. The aim of the study was to compare these two PF formulations in vitro for viability of the human corneal epithelial (HCE-T) cells and in vivo for ocular tolerability of the rabbit eye. METHOD: Viability of the HCE-T cells was measured by the MTS assay...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27347249/risk-factors-for-primary-open-angle-glaucoma-poag-progression-a-study-ruled-in-torino
#10
A G Actis, E Versino, B Brogliatti, T Rolle
PURPOSE: Aim of this retrospective, observational study is to describe features of a population sample, affected by primary open angle glaucoma (POAG) in order to evaluate damage progression on the basis of the emerged individual risk factors. METHODS: We included 190 caucasian patients (377 eyes), evaluating relationship between individual risk factors (explicative variables) and MD (Mean Deviation) of standard automated perimetry. We also considered the dependent variable NFI (Neural Fiber Index) of GDx scanning laser polarimetry...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27347248/lithium-induced-downbeat-nystagmus-and-horizontal-gaze-palsy
#11
Jesper Skovlund Jørgensen, Lisbeth Landschoff Lassen, Marianne Wegener
We report a case of lithium-induced downbeat nystagmus and horizontal gaze palsy in a 62-year-old woman who was treated for a bipolar affective disorder with lithium carbonate for one month. At presentation serum lithium was within therapeutic range. No alternative causes of the ocular motility disturbances were found, and the patient improved significantly as lithium carbonate was discontinued.
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27347247/evaluation-of-a-public-child-eye-health-tertiary-facility-for-pediatric-cataract-in-southern-nigeria-i-visual-acuity-outcome
#12
Roseline E Duke, Adedayo Adio, Sidney K Oparah, Friday Odey, Okon A Eyo
PURPOSE: A retrospective study of the outcome of congenital and developmental cataract surgery was conducted in a public child eye health tertiary facility in children <16 years of age in Southern Nigeria, as part of an evaluation. MATERIALS AND METHOD: Manual Small Incision Cataract Surgery with or without anterior vitrectomy was performed. The outcome measures were visual acuity (VA) and change (gain) in visual acuity. The age of the child at onset, duration of delay in presentation, ocular co-morbidity, non ocular co-morbidity, gender, and pre operative visual acuity were matched with postoperative visual acuity...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27347246/long-term-clinical-and-visual-outcomes-of-retrofixated-iris-claw-lenses-implantation-in-complicated-cases
#13
Sri Ganesh, Sheetal Brar, Kirti Relekar
AIMS: To evaluate the visual outcomes and complications after implantation of retrofixated iris claw (RFIC) lens in various challenging situations. SETTINGS AND DESIGN: Retrospective, single centre, 8 year clinical audit. MATERIALS AND METHODS: A retrospective analysis of cases who underwent RFIC lens implantation alone (group 1) or in combination with vitreoretinal (VR), corneal or glaucoma procedures (group 2) was performed. The main outcomes evaluated were corrected distant visual acuity (CDVA) and postoperative complications...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27073587/efficacy-and-safety-of-switching-latanoprost-monotherapy-to-bimatoprost-monotherapy-or-combination-of-brinzolamide-and-latanoprost
#14
Mitsuhiro Imasawa, Joji Tanabe, Fumiko Kashiwagi, Kenji Kashiwagi
PURPOSE: To prospectively assess the efficacy and safety of switching to bimatoprost monotherapy or brinzolamide and latanoprost combination therapy in patients who had been receiving latanoprost monotherapy. METHODS: A prospective, open-label study was conducted. Patients with primary open-angle glaucoma or ocular hypertension who had been receiving latanoprost monotherapy for three months or more were enrolled. Bimatoprost was substituted for latanoprost in one eye (BIM group), and brinzolamide was added to the latanoprost in the other eye (BRZ group) simultaneously...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27053973/serial-intravitreal-bevacizumab-injections-slow-the-progression-of-radiation-maculopathy-following-iodine-125-plaque-radiotherapy
#15
Andrew W Stacey, Hakan Demirci
BACKGROUND AND OBJECTIVE: To assess the outcomes of intravitreal bevacizumab injection in the management of radiation maculopathy secondary to plaque radiotherapy, and to identify optimal treatment strategies. STUDY DESIGN: A retrospective review of all choroidal melanoma patients at one referral center who were treated with plaque radiotherapy, subsequently developed radiation maculopathy, and received intravitreal bevacizumab. RESULTS: A total of 31 patients were identified...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27014390/managing-primary-angle-closure-glaucoma-the-role-of-lens-extraction-in-this-era
#16
Nafees Baig, Ka-Wai Kam, Clement C Y Tham
Trabeculectomy has been the gold standard in reducing intraocular pressure (IOP) in glaucoma patients, no matter it is angle closure or open angle glaucoma. However in primary angle closure glaucoma, no matter the lens is cataractous or not, it is likely to be pathological, this thicker than usual lens, with or without a more anterior position, is often regarded as a strong contributing factor to angle closure. Lens extraction, no matter it is cataractous or clear, can theoretically eliminate this anatomical predisposing factor of angle closure, and thus IOP can be reduced...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27014389/current-and-future-techniques-in-wound-healing-modulation-after-glaucoma-filtering-surgeries
#17
Masoumeh B Masoumpour, M Hossein Nowroozzadeh, M Reza Razeghinejad
Filtering surgeries are frequently used for controlling intraocular pressure in glaucoma patients. The long-term success of operation is intimately influenced by the process of wound healing at the site of surgery. Indeed, if has not been anticipated and managed accordingly, filtering surgery in high-risk patients could end up in bleb failure. Several strategies have been developed so far to overcome excessive scarring after filtering surgery. The principal step involves meticulous tissue handling and modification of surgical technique, which can minimize the severity of wound healing response at the first place...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27014388/current-and-future-of-laser-therapy-in-the-management-of-glaucoma
#18
Feyzahan Ekici, Michael Waisbourd, L Jay Katz
There has been tremendous progress in the past decades in the utilization of lasers for treating patients with glaucoma. This article reviews the use of lasers in different areas of glaucoma, including the shift from argon laser trabeculoplasty (ALT) to selective laser trabeculoplasty (SLT), laser trabeculoplasty as an initial treatment for glaucoma, new laser trabeculoplasty procedures under investigation, and other recent laser treatment modalities such as endoscopic cyclophotocoagulation and laser-assisted deep sclerectomy...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27014387/detecting-iop-fluctuations-in-glaucoma-patients
#19
Brenda Nuyen, Kaweh Mansouri
Lowering intraocular pressure (IOP) remains the guiding principle of glaucoma management. Although IOP is the only treatable risk factor, its 24-hour behavior is poorly understood. Current glaucoma management usually relies on single IOP measurements during clinic hours, even though IOP is a dynamic parameter with rhythms dependent on individual patients. It has further been shown that most glaucoma patients have their highest IOP measurements outside clinic hours. The fact that these IOP peaks go largely undetected may explain why certain patients progress in their disease despite treatment...
2016: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/27014386/intra-ocular-pressure-measurement-in-a-patient-with-a-thin-thick-or-abnormal-cornea
#20
Colin I Clement, Douglas G A Parker, Ivan Goldberg
Accurate measurement of intra-ocular pressure is a fundamental component of the ocular examination. The most common method of measuring IOP is by Goldmann applanation tonometry, the accuracy of which is influenced by the thickness and biomechanical properties of the cornea. Algorithms devised to correct for corneal thickness to estimate IOP oversimplify the effects of corneal biomechanics. The viscous and elastic properties of the cornea influence IOP measurements in unpredictable ways, a finding borne out in studies of patients with inherently abnormal and surgically altered corneal biomechanics...
2016: Open Ophthalmology Journal
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