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Open Neuroimaging Journal

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https://www.readbyqxmd.com/read/28979609/examining-microstructural-white-matter-in-active-duty-soldiers-with-a-history-of-mild-traumatic-brain-injury-and-traumatic-stress
#1
Michael N Dretsch, Rael T Lange, Jeffery S Katz, Adam Goodman, Thomas A Daniel, Gopikrishna Deshpande, Thomas S Denney, Grant L Iverson, Jennifer L Robinson
BACKGROUND: There is a high comorbidity of posttraumatic stress (PTS) and mild traumatic brain injury (mTBI), with largely overlapping symptomatology, in military service members. OBJECTIVE: To examine white matter integrity associated with PTS and mTBI as assessed using diffusion tensor imaging (DTI). METHOD: Seventy-four active-duty U.S. soldiers with PTS (n = 16) and PTS with co-morbid history of mTBI (PTS/mTBI; n = 28) were compared to a military control group (n = 30)...
2017: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/28761571/extending-inferential-group-analysis-in-type-2-diabetic-patients-with-multivariate-glm-implemented-in-spm8
#2
Fábio S Ferreira, João M S Pereira, João V Duarte, Miguel Castelo-Branco
BACKGROUND: Although voxel based morphometry studies are still the standard for analyzing brain structure, their dependence on massive univariate inferential methods is a limiting factor. A better understanding of brain pathologies can be achieved by applying inferential multivariate methods, which allow the study of multiple dependent variables, e.g. different imaging modalities of the same subject. OBJECTIVE: Given the widespread use of SPM software in the brain imaging community, the main aim of this work is the implementation of massive multivariate inferential analysis as a toolbox in this software package...
2017: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/28660006/convexity-subarachnoid-hemorrhage-pseudomonas-aeruginosa-pa-infective-endocarditis-and-left-atrial-appendage-occluder-laao-device-infection-a-case-report
#3
Monique Boukobza, Ibtissem Smaali, Xavier Duval, Jean-Pierre Laissy
An 83 year-old-man with left atrial appendage occluder (LAAO) developed Pseudomonas Aeruginosa (PA) infective endocarditis. MRI at day 3 of onset showed distal small infarcts in both middle cerebral arteries and left postero-inferior cerebellar artery territories. MRI at day 6 revealed two sites of convexity subarachnoid hemorrhage (cSAH). MRA and CTA failed to reveal a Mycotic aneurysm. The radiologic findings favor the assumption of necrosis of distal branches of mca or of pial arteries wall. This case present three unusual features: the presence of localized cSAH after initiation of antibiotherapy without mycotic aneurysm being individualized; the late occurrence of infective endocarditis after LAAO implantation; the very rare occurrence of PA in prosthetic infections...
2017: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/28567171/a-functional-mri-based-model-for-individual-memory-assessment-in-patients-eligible-for-anterior-temporal-lobe-resection
#4
Maria Strandberg, Peter Mannfolk, Lars Stenberg, Hanna Ljung, Ia Rorsman, Elna-Marie Larsson, Danielle van Westen, Kristina Källén
TITLE: A functional (f) MRI-based model for individual memory assessment in patients eligible for temporal lobe resection. AIM: To investigate if pre-operative fMRI memory paradigms, add predictive information with regard to post-surgical memory deficits. METHODS: Fourteen pharmacoresistant Temporal Lobe Epilepsy (TLE) patients accepted for Anterior Temporal Lobe Resection (ATLR) were included. A clinical risk assessment score (RAS 0-3) was constructed from structural MRI, neuropsychological testing and hemisphere dominance...
2017: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/28553427/functional-evaluation-of-awareness-in-vegetative-and-minimally-conscious-state
#5
Silvia Marino, Lilla Bonanno, Rosella Ciurleo, Annalisa Baglieri, Rosa Morabito, Silvia Guerrera, Carmela Rifici, Antonio Giorgio, Placido Bramanti, Nicola De Stefano
OBJECTIVE: The aim of this study was to assess differences in brain activation in a large sample of Vegetative State (VS) and Minimally Conscious State (MCS) patients, using functional magnetic resonance imaging (fMRI). METHODS: We studied 50 patients four to seven months after brain injury. By using international clinical criteria and validated behavioural scales such as the Glasgow Coma Scale and the Clinical Unawareness Assessment Scale, the patients were grouped into VS (n=23) and MCS (n=27)...
2017: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/28144384/manganese-enhanced-mri-offers-correlation-with-severity-of-spinal-cord-injury-in-experimental-models
#6
Nikolay L Martirosyan, Gregory H Turner, Jason Kaufman, Arpan A Patel, Evgenii Belykh, M Yashar S Kalani, Nicholas Theodore, Mark C Preul
BACKGROUND: Spinal cord injuries (SCI) are clinically challenging, because neural regeneration after cord damage is unknown. In SCI animal models, regeneration is evaluated histologically, requiring animal sacrifice. Noninvasive techniques are needed to detect longitudinal SCI changes. OBJECTIVE: To compare manganese-enhanced magnetic resonance imaging (MRI [MEMRI]) in hemisection and transection of SCI rat models with diffusion tensor imaging (DTI) and histology...
2016: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/27867436/putamen-activation-represents-an-intrinsic-positive-prediction-error-signal-for-visual-search-in-repeated-configurations
#7
Susanne Sommer, Stefan Pollmann
We investigated fMRI responses to visual search targets appearing at locations that were predicted by the search context. Based on previous work in visual category learning we expected an intrinsic reward prediction error signal in the putamen whenever the target appeared at a location that was predicted with some degree of uncertainty. Comparing target appearance at locations predicted with 50% probability to either locations predicted with 100% probability or unpredicted locations, increased activation was observed in left posterior putamen and adjacent left posterior insula...
2016: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/27867434/exploring-the-neurocircuitry-underpinning-predictability-of-threat-in-soldiers-with-ptsd-compared-to-deployment-exposed-controls
#8
Michael N Dretsch, Kimberly H Wood, Thomas A Daniel, Jeffrey S Katz, Gopikrishna Deshpande, Adam M Goodman, Muriah D Wheelock, Kayli B Wood, Thomas S Denney, Stephanie Traynham, David C Knight
BACKGROUND: Prior work examining emotional dysregulation observed in posttraumatic stress disorder (PTSD) has primarily been limited to fear-learning processes specific to anticipation, habituation, and extinction of threat. In contrast, the response to threat itself has not been systematically evaluated. OBJECTIVE: To explore potential disruption in fear conditioning neurocircuitry in service members with PTSD, specifically in response to predictable versus unpredictable threats...
2016: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/27843514/attentional-networks-in-adolescents-with-high-functioning-autism-an-fmri-investigation
#9
Elizabeth C Hames, Ravi Rajmohan, Dan Fang, Ronald Anderson, Mary Baker, David M Richman, Michael O'Boyle
BACKGROUND: Attentional deficits in Autism spectrum disorder (ASD) are often noted, but their specific nature remains unclear. OBJECTIVE: The present study used the child Attentional Network Task (Child ANT) in combination with functional magnetic resonance imaging (fMRI) to determine if the consistently cited deficits of orienting attention are truly due to dysfunctions of orienting-based networks. We hypothesized that these observations are, in fact, a reflection of executive dysfunctions...
2016: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/27708745/sex-differences-in-gamma-band-functional-connectivity-between-the-frontal-lobe-and-cortical-areas-during-an-auditory-oddball-task-as-revealed-by-imaginary-coherence-assessment
#10
Toshiro Fujimoto, Eiichi Okumura, Atsushi Kodabashi, Kouzou Takeuchi, Toshiaki Otsubo, Katsumi Nakamura, Kazutaka Yatsushiro, Masaki Sekine, Shinichiro Kamiya, Susumu Shimooki, Toshiyo Tamura
We studied sex-related differences in gamma oscillation during an auditory oddball task, using magnetoencephalography and electroencephalography assessment of imaginary coherence (IC). We obtained a statistical source map of event-related desynchronization (ERD) / event-related synchronization (ERS), and compared females and males regarding ERD / ERS. Based on the results, we chose respectively seed regions for IC determinations in low (30-50 Hz), mid (50-100 Hz) and high gamma (100-150 Hz) bands. In males, ERD was increased in the left posterior cingulate cortex (CGp) at 500 ms in the low gamma band, and in the right caudal anterior cingulate cortex (cACC) at 125 ms in the mid-gamma band...
2016: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/27499824/primary-intracranial-choriocarcinoma-located-in-the-suprasellar-region
#11
Xiuli Li, Kazuhiro Murayama, Ayumi Watanabe, Masato Abe, Hiroshi Toyama
A 10 year old girl was admitted to our hospital due to headache, nausea, and weight loss for about half a year. She also had visual field disorders. Suprasellar tumor was found by X-ray computed tomography, and magnetic resonance imaging showed a ring-like lobulated enhanced mass with hemorrhage and necrosis. Biopsy of this lesion showed primary intracranial choriocarcinoma on histopathological examination. The serum human chorionic gonadotropin (hCG) level was measured after the biopsy and was elevated at 71,298...
2016: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/27347266/long-term-six-years-clinical-outcome-discrimination-of-patients-in-the-vegetative-state-could-be-achieved-based-on-the-operational-architectonics-eeg-analysis-a-pilot-feasibility-study
#12
Andrew A Fingelkurts, Alexander A Fingelkurts, Sergio Bagnato, Cristina Boccagni, Giuseppe Galardi
Electroencephalogram (EEG) recordings are increasingly used to evaluate patients with disorders of consciousness (DOC) or assess their prognosis outcome in the short-term perspective. However, there is a lack of information concerning the effectiveness of EEG in classifying long-term (many years) outcome in chronic DOC patients. Here we tested whether EEG operational architectonics parameters (geared towards consciousness phenomenon detection rather than neurophysiological processes) could be useful for distinguishing a very long-term (6 years) clinical outcome of DOC patients whose EEGs were registered within 3 months post-injury...
2016: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/27347265/the-role-of-neuroimaging-techniques-in-establishing-diagnosis-prognosis-and-therapy-in-disorders-of-consciousness
#13
Olivia Gosseries, Francesca Pistoia, Vanessa Charland-Verville, Antonio Carolei, Simona Sacco, Steven Laureys
Non-communicative brain damaged patients raise important clinical and scientific issues. Here, we review three major pathological disorders of consciousness: coma, the unresponsive wakefulness syndrome and the minimally conscious state. A number of clinical studies highlight the difficulty in making a correct diagnosis in patients with disorders of consciousness based only on behavioral examinations. The increasing use of neuroimaging techniques allows improving clinical characterization of these patients. Recent neuroimaging studies using positron emission tomography, functional magnetic resonance imaging, electroencephalography and transcranial magnetic stimulation can help assess diagnosis, prognosis, and therapeutic treatment...
2016: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/27347264/the-chief-role-of-frontal-operational-module-of-the-brain-default-mode-network-in-the-potential-recovery-of-consciousness-from-the-vegetative-state-a-preliminary-comparison-of-three-case-reports
#14
Alexander A Fingelkurts, Andrew A Fingelkurts, Sergio Bagnato, Cristina Boccagni, Giuseppe Galardi
It has been argued that complex subjective sense of self is linked to the brain default-mode network (DMN). Recent discovery of heterogeneity between distinct subnets (or operational modules - OMs) of the DMN leads to a reconceptualization of its role for the experiential sense of self. Considering the recent proposition that the frontal DMN OM is responsible for the first-person perspective and the sense of agency, while the posterior DMN OMs are linked to the continuity of 'I' experience (including autobiographical memories) through embodiment and localization within bodily space, we have tested in this study the hypothesis that heterogeneity in the operational synchrony strength within the frontal DMN OM among patients who are in a vegetative state (VS) could inform about a stable self-consciousness recovery later in the course of disease (up to six years post-injury)...
2016: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/27347263/disembodied-mind-cortical-changes-following-brainstem-injury-in-patients-with-locked-in-syndrome
#15
Francesca Pistoia, Riccardo Cornia, Massimiliano Conson, Olivia Gosseries, Antonio Carolei, Simona Sacco, Carlo C Quattrocchi, Carlo A Mallio, Cristina Iani, Debora Di Mambro, Marco Sarà
Locked-in syndrome (LIS) following ventral brainstem damage is the most severe form of motor disability. Patients are completely entrapped in an unresponsive body despite consciousness is preserved. Although the main feature of LIS is this extreme motor impairment, minor non-motor dysfunctions such as motor imagery defects and impaired emotional recognition have been reported suggesting an alteration of embodied cognition, defined as the effects that the body and its performances may have on cognitive domains...
2016: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/27347262/challenges-and-pitfalls-associated-with-diagnostic-and-prognostic-applications-of-functional-neuroimaging-in-disorders-of-consciousness
#16
Yelena G Bodien, Joseph T Giacino
The diagnostic assessment of patients with disorder of consciousness is currently based on clinical testing at the bedside and prone to a high error rate in the assessment of the degree of conscious awareness. Investigation of more objective assessment strategies, such as the use of functional magnetic resonance imaging (fMRI) to detect conscious awareness, are becoming increasingly popular in the research community. However, inherent challenges to the use of fMRI threaten its validity as a diagnostic tool and will need to be resolved prior to its integration into the clinical setting...
2016: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/27347261/the-role-of-neuroimaging-in-the-diagnosis-prognosis-and-management-of-disorders-of-consciousness-and-locked-in-syndrome
#17
Francesca Pistoia, Antonio Carolei
Disorders of consciousness and locked-in syndrome are two completely different neurological conditions which share unresponsiveness or minimal responsiveness at an observable behavioral level. The key element of disorders of consciousness is the loss of self- and environmental awareness, while the main feature of locked-in syndrome is extreme motor entrapment despite preserved awareness. In both cases accurate diagnosis may come late and patients are at risk of being wrongly diagnosed and missing out on appropriate rehabilitative opportunities...
2016: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/27014392/does-congenital-deafness-affect-the-structural-and-functional-architecture-of-primary-visual-cortex
#18
C R Smittenaar, M MacSweeney, M I Sereno, D S Schwarzkopf
Deafness results in greater reliance on the remaining senses. It is unknown whether the cortical architecture of the intact senses is optimized to compensate for lost input. Here we performed widefield population receptive field (pRF) mapping of primary visual cortex (V1) with functional magnetic resonance imaging (fMRI) in hearing and congenitally deaf participants, all of whom had learnt sign language after the age of 10 years. We found larger pRFs encoding the peripheral visual field of deaf compared to hearing participants...
2016: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/26401174/arachnoiditis-ossificans-a-rare-cause-of-progressive-myelopathy
#19
Christopher J Steel, Erik L Abrames, William T O'Brien
Arachnoiditis ossificans is a rare cause of chronic, progressive myelopathy. In contrast to the more common benign causes of meningeal calcification, arachnoiditis ossificans results in replacement of portions of the spinal arachnoid by bone as an end-stage complication of adhesive arachnoiditis. It is usually the sequela of prior trauma or interventional procedures. Prognosis and treatment options depend upon the location and degree of spinal stenosis with thoracic involvement being more common and more severe than lumbar spine involvement...
2015: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/26401173/experimental-fusion-of-contrast-enhanced-high-field-magnetic-resonance-imaging-and-high-resolution-micro-computed-tomography-in-imaging-the-mouse-inner-ear
#20
S Allen Counter, Peter Damberg, Sahar Nikkhou Aski, Kálmán Nagy, Cecilia Engmér Berglin, Göran Laurell
OBJECTIVE: Imaging cochlear, vestibular, and 8th cranial nerve abnormalities remains a challenge. In this study, the membranous and osseous labyrinths of the wild type mouse inner ear were examined using volumetric data from ultra high-field magnetic resonance imaging (MRI) with gadolinium contrast at 9.4 Tesla and high-resolution micro-computed tomography (µCT) to visualize the scalae and vestibular apparatus, and to establish imaging protocols and parameters for comparative analysis of the normal and mutant mouse inner ear...
2015: Open Neuroimaging Journal
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