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Open Microbiology Journal

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https://www.readbyqxmd.com/read/28659996/the-immunomodulatory-effect-of-trichophyton-rubrum-exoantigens-in-the-treatment-of-experimental-septic-arthritis
#1
Seyed A Ghiasian, Amir H Maghsood, Asadollah Abniki, Abbas Mirshafiey
BACKGROUND: Understanding the nature and function of fungal exoantigens might lead to novel approaches in the treatment and prophylaxis of some infectious diseases. Septic arthritis represents a serious problem for medicine due to the high incidence rate and severe complications. OBJECTIVE: The present study aimed at assessing the immunomodulatory effects of Trichophyton rubrum culture filtrate as a novel compound in experimental septic arthritis. METHOD: The septic arthritis was haematogenously induced in Sprague-Dawley rats by a single intravenous injection of 10(9) colony forming units of the human clinical isolate Staphylococcus aureus producing toxic shock syndrome toxin-1...
2017: Open Microbiology Journal
https://www.readbyqxmd.com/read/28603564/a-study-on-the-microbiological-status-of-mineral-drinking-water
#2
Faria Y Aditi, Shafkat S Rahman, Md M Hossain
INTRODUCTION: Water-borne diseases constitute a major health burden in Bangladesh. The objective of this study was to assess the overall quality of mineral water samples that obtained from different shops of Dhaka city. MATERIAL AND METHODS: To achieve the above-mentioned objective, methods of heterotrophic plate count (HPC) and total coliform count (TCC) were applied. Moreover, isolated colony from mineral water samples were characterized by using biochemical and antimicrobial susceptibility tests...
2017: Open Microbiology Journal
https://www.readbyqxmd.com/read/28567147/ozone-sensitivity-and-catalase-activity-in-pigmented-and-non-pigmented-strains-of-serratia-marcescens
#3
José de Ondarza
BACKGROUND: Ozone exposure rapidly leads to bacterial death, making ozone an effective disinfectant in food industry and health care arena. However, microbial defenses may moderate this effect and play a role in the effective use of oxidizing agents for disinfection. Serratia marcescens is an opportunistic pathogen, expressing genes differentially during infection of a human host. A better understanding of regulatory systems that control expression of Serratia's virulence genes and defenses is therefore valuable...
2017: Open Microbiology Journal
https://www.readbyqxmd.com/read/28567146/virulence-factors-associated-with-enterococcus-faecalis-infective-endocarditis-a-mini-review
#4
REVIEW
Kristian T Madsen, Marianne N Skov, Sabine Gill, Michael Kemp
INTRODUCTION: The enterococci are accountable for up to 20% of all cases of infective endocarditis, with Enterococcus faecalis being the primary causative isolate. Infective endocarditis is a life-threatening infection of the endocardium that results in the formation of vegetations. Based on a literature review, this paper provides an overview of the virulence factors associated with E. faecalis infective endocarditis. Furthermore, it reports the effects of active or passive immunization against some of these involved factors...
2017: Open Microbiology Journal
https://www.readbyqxmd.com/read/28553417/synergistic-effect-of-colistin-and-rifampin-against-multidrug-resistant-acinetobacter-baumannii-a-systematic-review-and-meta-analysis
#5
REVIEW
Maryam Mohammadi, Hatef Khayat, Koroush Sayehmiri, Setareh Soroush, Fatemeh Sayehmiri, Somayeh Delfani, Lidija Bogdanovic, Morovat Taherikalani
The existence of infections caused by multidrug resistant (MDR) Acinetobacter baumannii is a growing problem because of the difficulty to treat them. We examined the published literature and focused our analysis on the investigation of the synergism of colistin and rifampin against MDR A. baumannii isolates via systematic review and meta-analysis. A systematic literature search was performed using the following 4 databases (PubMed, Scopus, EMBASE and ISI Web of Sciences). The related articles were evaluated during the period from December 2014 to January 2015...
2017: Open Microbiology Journal
https://www.readbyqxmd.com/read/28553416/understanding-the-mechanism-of-bacterial-biofilms-resistance-to-antimicrobial-agents
#6
REVIEW
Shriti Singh, Santosh Kumar Singh, Indrajit Chowdhury, Rajesh Singh
A biofilm is a group of microorganisms, that causes health problems for the patients with indwelling medical devices via attachment of cells to the surface matrix. It increases the resistance of a microorganism for antimicrobial agents and developed the human infection. Current strategies are removed or prevent the microbial colonies from the medical devices, which are attached to the surfaces. This will improve the clinical outcomes in favor of the patients suffering from serious infectious diseases. Moreover, the identification and inhibition of genes, which have the major role in biofilm formation, could be the effective approach for health care systems...
2017: Open Microbiology Journal
https://www.readbyqxmd.com/read/28553415/use-of-proviral-dna-to-investigate-virus-resistance-mutations-in-hiv-infected-zimbabweans
#7
Tutsirai V Musingwini, Danai T Zhou, Doreen Mhandire, Kerina Duri, Exnevia Gomo, Olav Oktedalen, Benjamin Chimukangara, Tinei Shamu, Sandra Shawarira-Bote, Collet Dandara, Babill Stray-Pedersen
BACKGROUND: Antiretroviral therapy (ART) to suppress HIV replication has reduced morbidity and mortality yet effectiveness of current HIV drugs is threatened by HIV drug resistance (HIVDR) mutations. OBJECTIVE: To determine HIVDR mutations using proviral DNA from specimens of patients presenting to an HIV treatment clinic. METHODS: DNA from 103 patients, 86 treatment-experienced, 17 treatment-naïve, were genotyped for the HIV-1C reverse transcriptase gene (RT; codons 21-304) using Sanger sequencing and sequences analyzed using Sequencher software...
2017: Open Microbiology Journal
https://www.readbyqxmd.com/read/28553414/esbl-production-among-e-coli-and-klebsiella-spp-causing-urinary-tract-infection-a-hospital-based-study
#8
Pooja Shakya, Dhiraj Shrestha, Elina Maharjan, Vijay K Sharma, Rabin Paudyal
INTRODUCTION: Increase in extended-spectrum β-lactamases (ESBL) producing microbes in recent years has led to limitations of treatment options. This study aimed to assess the prevalence of ESBL producing E. coli and Klebsiella spp. at a tertiary hospital in Nepal. METHODS: A total of 2209 non-repetitive mid-stream urine (MSU) samples were collected during the study period (March to September 2014). Identification of the isolates was done by Gram's staining followed by biochemical tests...
2017: Open Microbiology Journal
https://www.readbyqxmd.com/read/28217194/prevalence-antibiogram-and-molecular-characterization-of-comunity-acquired-methicillin-resistant-staphylococcus-aureus-in-awka-anambra-nigeria
#9
Blessing Ike, Malachy C Ugwu, Moses N Ikegbunam, David Nwobodo, Chika Ejikeugwu, Thaddeus Gugu, Charles O Esimone
OBJECTIVES: This study evaluated the prevalence, antibiogram and molecular features of CA-MRSA in Awka, Nigeria. METHODS: Confirmation of MRSA was done by testing resistance to oxacillin (1µg), cloxacillin (5µg) and cefoxitin (30µg) on sterile Mueller Hinton agar supplemented with 4% sodium chloride. The MRSA strains were subjected to antimicrobial susceptibility testing using Kirby-Bauer disc diffusion method. Minimum inhibitory concentration was determined using agar dilution method...
2016: Open Microbiology Journal
https://www.readbyqxmd.com/read/28217193/letter-to-the-editor-coinfection-of-adenovirus-with-the-members-of-herpesviridae-in-ophthalmic-pterygium
#10
Mishar Kelishadi, Mandana Kelishadi, Alijan Tabarraei
No abstract text is available yet for this article.
2016: Open Microbiology Journal
https://www.readbyqxmd.com/read/28217192/matrix-assisted-laser-desorption-ionization-time-of-flight-mass-spectrometry-maldi-tof-ms-as-a-reliable-tool-to-identify-species-of-catalase-negative-gram-positive-cocci-not-belonging-to-the-streptococcus-genus
#11
Marisa Almuzara, Claudia Barberis, Viviana Rojas Velázquez, Maria Soledad Ramirez, Angela Famiglietti, Carlos Vay
OBJECTIVE: To evaluate the performance of matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS) by using 190 Catalase-negative Gram-Positive Cocci (GPC) clinical isolates. METHODS: All isolates were identified by conventional phenotypic tests following the proposed scheme by Ruoff and Christensen and MALDI-TOF MS (Bruker Daltonics, BD, Bremen, Germany). Two different extraction methods (direct transfer formic acid method on spot and ethanol formic acid extraction method) and different cut-offs for genus/specie level identification were used...
2016: Open Microbiology Journal
https://www.readbyqxmd.com/read/28077976/antifungal-activity-and-aflatoxin-degradation-of-bifidobacterium-bifidum-and-lactobacillus-fermentum-against-toxigenic-aspergillus-parasiticus
#12
Roshanak Daie Ghazvini, Ebrahim Kouhsari, Ensieh Zibafar, Seyed Jamal Hashemi, Abolfazl Amini, Farhad Niknejad
Food and feedstuff contamination with aflatoxins (AFTs) is a serious health problem for humans and animals, especially in developing countries. The present study evaluated antifungal activities of two lactic acid bacteria (LAB) against growth and aflatoxin production of toxigenic Aspergillus parasiticus. The mycelial growth inhibition rate of A. parasiticus PTCC 5286 was investigated in the presence of Bifidobacterium bifidum PTCC 1644 and Lactobacillus fermentum PTCC 1744 by the pour plate method. After seven days incubation in yeast extract sucrose broth at 30°C, the mycelial mass was weighed after drying...
2016: Open Microbiology Journal
https://www.readbyqxmd.com/read/28077975/evaluate-the-relationship-between-class-1-integrons-and-drug-resistance-genes-in-clinical-isolates-of-pseudomonas-aeruginosa
#13
Seyed Mohammad Javad Hosseini, Niloofar Shoaee Naeini, Azad Khaledi, Seyede Fatemeh Daymad, Davoud Esmaeili
BACKGROUND: The prevalence of resistant Pseudomonas aeruginosa isolates is increasing and it is considered as one of the major public health concerns in the world. The association between integrons and drug resistance has been proven and evidences suggest that integrons are coding and responsible for dissemination of antibiotic resistance among P. aeruginosa isolates. OBJECTIVE: This study is aimed to evaluate the relationship between class 1 integrons and drug resistance genes in clinical isolates of P...
2016: Open Microbiology Journal
https://www.readbyqxmd.com/read/28077974/cardiobacterium-hominis-and-cardiobacterium-valvarum-two-case-stories-with-infective-episodes-in-pacemaker-treated-patients
#14
Tina Bennett Bonavent, Xiaohui Chen Nielsen, Kjeld Skødebjerg Kristensen, Nikolaj Ihlemann, Claus Moser, Jens Jørgen Christensen
INTRODUCTION: Cardiobacterium hominis and Cardiobacterium valvarum are well known, though rare, etiologic agents of infective endocarditis. Cardiac devices are increasingly implanted. CASE REPORTS: Two cases of infective episodes in pacemaker (PM) treated patients with respectively C. hominis and C. valvarum are presented. In one case blood-culture bottles yielded growth of C. hominis at two episodes with two years apart. At the second episode a vegetation was recognized at the PM lead and the PM device and lead was removed...
2016: Open Microbiology Journal
https://www.readbyqxmd.com/read/28077973/respiratory-tularemia-francisella-tularensis-and-microarray-probe-designing
#15
Reza Ranjbar, Payam Behzadi, Caterina Mammina
BACKGROUND: Francisella tularensis (F. tularensis) is the etiological microorganism for tularemia. There are different forms of tularemia such as respiratory tularemia. Respiratory tularemia is the most severe form of tularemia with a high rate of mortality; if not treated. Therefore, traditional microbiological tools and Polymerase Chain Reaction (PCR) are not useful for a rapid, reliable, accurate, sensitive and specific diagnosis. But, DNA microarray technology does. DNA microarray technology needs to appropriate microarray probe designing...
2016: Open Microbiology Journal
https://www.readbyqxmd.com/read/27867430/evaluation-in-mouse-model-of-combined-virus-bacterial-vaccine-based-on-attenuated-influenza-a-h7n3-virus-and-the-group-b-streptococcus-recombinant-polypeptides
#16
Yulia A Desheva, Galina F Leontieva, Tatiana A Kramskaya, Tatiana A Smolonogina, Kornelia B Grabovskaya, Irina V Kiseleva, Larisa G Rudenko, Alexander N Suvorov
BACKGROUND: Secondary bacterial influenza complications are a common cause of excesses morbidity and mortality, which determines the need to develop means for specific prophylaxis. Group B streptococcal infection is especially common cause of pneumonia among children and the elderly with underlying conditions. Here we investigate in a mouse model the effects of combined intranasal immunization using live attenuated influenza vaccine and recombinant polypeptides based on group B Streptococcus surface proteins...
2016: Open Microbiology Journal
https://www.readbyqxmd.com/read/27857820/detection-of-specific-antibody-reactivity-to-toxocara-larval-excretory-secretory-antigens-in-asthmatic-patients-5-15-years
#17
Mahdi Mosayebi, Latif Moini, Reza Hajihossein, Mojtaba Didehdar, Zahra Eslamirad
BACKGROUND & PURPOSE: Humans act as an intermediate host for Toxocara canis and Toxocara cati. Toxocara may be an important risk factor for asthma in humans. The aim of the present study was to evaluate immunoglobulin G (IgG) anti-Toxocara canis antibody, using enzyme-linked immunosorbent assay (ELISA) in asthmatic patients (aged 5-15 years), referring to a clinic of pulmonary diseases in Arak, Iran. MATERIALS & METHODS: In this bi-group cross sectional study, serum samples were collected from 110 children with confirmed asthma and 70 children without asthma within one year...
2016: Open Microbiology Journal
https://www.readbyqxmd.com/read/27651848/a-systemic-review-on-staphylococcal-scalded-skin-syndrome-ssss-a-rare-and-critical-disease-of-neonates
#18
Arun K Mishra, Pragya Yadav, Amrita Mishra
The symptoms of Staphylococcal scalded skin syndrome (SSSS) include blistering of skin on superficial layers due to the exfoliative toxins released from Staphylococcus aureus. After the acute exfoliation of skin surface, erythematous cellulitis occurs. The SSSS may be confined to few blisters localized to the infection site and spread to severe exfoliation affecting complete body. The specific antibodies to exotoxins and increased clearence of exotoxins decrease the frequency of SSSS in adults. Immediate medication with parenteral anti-staphylococcal antibiotics is mandatory...
2016: Open Microbiology Journal
https://www.readbyqxmd.com/read/27651847/the-diversity-of-sulfide-oxidation-and-sulfate-reduction-genes-expressed-by-the-bacterial-communities-of-the-cariaco-basin-venezuela
#19
Maria J Rodriguez-Mora, Virginia P Edgcomb, Craig Taylor, Mary I Scranton, Gordon T Taylor, Andrei Y Chistoserdov
Qualitative expression of dissimilative sulfite reductase (dsrA), a key gene in sulfate reduction, and sulfide:quinone oxidoreductase (sqr), a key gene in sulfide oxidation was investigated. Neither of the two could be amplified from mRNA retrieved with Niskin bottles but were amplified from mRNA retrieved by the Deep SID. The sqr and sqr-like genes retrieved from the Cariaco Basin were related to the sqr genes from a Bradyrhizobium sp., Methylomicrobium alcaliphilum, Sulfurovum sp. NBC37-1, Sulfurimonas autotrophica, Thiorhodospira sibirica and Chlorobium tepidum...
2016: Open Microbiology Journal
https://www.readbyqxmd.com/read/27478518/comparison-between-pathogen-associated-laboratory-and-clinical-parameters-in-early-onset-sepsis-of-the-newborn
#20
Bernhard Resch, Renoldner B, Hofer N
OBJECTIVES: To identify laboratory and clinical characteristics of different pathogens associated with early-onset sepsis (EOS) of the newborn. METHODS: Newborns with EOS were retrospectively analyzed regarding laboratory and clinical parameters associated with the identified pathogen. RESULTS: We identified 125 newborns having diagnosis of culture proven EOS between 1993 and 2011. One hundred cases had diagnosis of group B streptococci (GBS) infection (80%), 11 had Escherichia coli (8...
2016: Open Microbiology Journal
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