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Open AIDS Journal

Marion Peyre, Aurélie Gauchet, Matthieu Roustit, Pascale Leclercq, Olivier Epaulard
BACKGROUND: Physician attitude influences the way patients cope with diagnosis and therapy in chronic severe diseases such as cancer. Previous studies showed that such an effect exists in HIV care; it is likely that it begins with the first contact with a physician. OBJECTIVE: We aimed to explore in HIV-infected persons their perception of the first consultation they had with an HIV specialist (PFC-H), and whether this perception correlates with adherence to antiretroviral therapy...
2016: Open AIDS Journal
William K Adih, Richard M Selik, H Irene Hall, Aruna Surendera Babu, Ruiguang Song
BACKGROUND: Published death rates for persons with HIV have not distinguished deaths due to HIV from deaths due to other causes. Cause-specific death rates would allow better assessment of care needs. METHODS: Using data reported to the US national HIV surveillance system, we examined a) associations between selected decedent characteristics and causes of death during 2007-2011, b) trends in rates of death due to underlying causes among persons with AIDS during 1990-2011, and among all persons with diagnosed HIV infection (with or without AIDS) during 2000-2011...
2016: Open AIDS Journal
Ronaldo Iachan, Christopher H Johnson, Richard L Harding, Tonja Kyle, Pedro Saavedra, Emma L Frazier, Linda Beer, Christine L Mattson, Jacek Skarbinski
BACKGROUND: Health surveys of the general US population are inadequate for monitoring human immunodeficiency virus (HIV) infection because the relatively low prevalence of the disease (<0.5%) leads to small subpopulation sample sizes. OBJECTIVE: To collect a nationally and locally representative probability sample of HIV-infected adults receiving medical care to monitor clinical and behavioral outcomes, supplementing the data in the National HIV Surveillance System...
2016: Open AIDS Journal
Daniel B Chastain, Travis S King, Kayla R Stover
BACKGROUND: Increasing rates of HIV have been observed in women, African Americans, and Hispanics, particularly those residing in rural areas of the United States. Although cardiovascular (CV) complications in patients infected with human immunodeficiency virus (HIV) have significantly decreased following the introduction of antiretroviral therapy on a global scale, in many rural areas, residents face geographic, social, and cultural barriers that result in decreased access to care. Despite the advancements to combat the disease, many patients in these medically underserved areas are not linked to care, and fewer than half achieve viral suppression...
2016: Open AIDS Journal
Dickson Shey Nsagha, Innocent Lange, Peter Nde Fon, Jules Clement Nguedia Assob, Elvis Asangbeng Tanue
BACKGROUND: HIV and AIDS are major public health problems in the world and Africa. In Cameroon, the HIV prevalence is 5.1%. Cellphones have been found to be useful in the provision of modern health care services using short message services (SMS). This study assessed the effectiveness of SMS in improving the adherence of people living with HIV and AIDS to their treatment and care in Cameroon. METHODS: This intervention study used a randomized controlled trial design...
2016: Open AIDS Journal
Maria Concetta Postorino, Eugenia Quiros-Roldan, Franco Maggiolo, Simona Di Giambenedetto, Nicoletta Ladisa, Giuseppe Lapadula, Silvia Lorenzotti, Laura Sighinolfi, Filippo Castelnuovo, Massimo Di Pietro, Daria Gotti, Nicola Mazzini, Carlo Torti
BACKGROUND AND OBJECTIVES: Renal toxicity due to tenofovir (TDF) has been largely described in patients with HIV infection. However, other antiretroviral drugs (such as atazanavir [ATV], especially when boosted by ritonavir, ATV/r) could perpetuate some degrees of renal impairment with or without TDF co-administration. Also, possible benefits of stopping TDF in patients without renal diseases is not well known. This study aimed at exploring evolution of renal function and lipid profile after switching from tenofovir/emtricitabine (TDF/FTC) to abacavir/lamivudine (ABC/3TC), maintaining the ATV/r component of the regimen...
2016: Open AIDS Journal
Debra L Karch, Kristen Mahle Gray, Jing Shi, H Irene Hall
OBJECTIVES: Assess outcomes along the care continuum for HIV-infected people who inject drugs (PWID), by type of facility and stage of infection at diagnosis. METHODS: Data reported by 28 jurisdictions to the National HIV Surveillance System by December 2014 were used to identify PWID aged ≥13 years, diagnosed with HIV infection before December 31, 2013. Analyses used the CDC definition of linkage to care (LTC), retention in care (RIC), and viral suppression (VS), and are stratified by age, sex, race/ethnicity, and type of facility and stage of HIV infection at diagnosis...
2016: Open AIDS Journal
Minsoo Jung
This qualitative study investigates the different methods for selecting sex partners by Korean homosexuals considering factors related to homosexual identity and sexual behavior. We take the approach of the grounded theory to examine the issue of sexual partnering of men who have sex with men (MSM). In-depth interviews of urban MSM and bisexual men were conducted. The snowball sampled through a MSM portal web site. Three key informants from the several areas were collected through a MSM portal website, and then, participants were gradually recruited with the snowball samplings in South Korea, 2011 (n=32)...
2016: Open AIDS Journal
Eric Houston, Thomas Lyons, Brenda Wolfe, Norma Rolfsen, Maryanne Williams, Monique Rucker, Nancy Glick
OBJECTIVE: While a growing body of research indicates that implicit cognitive processes play an important role in a range of health behaviors, the assessment of these impulsive, associative mental processes among patients living with HIV has received little attention. This preliminary study explored how multidimensional scaling (MDS) could be used to assess implicit cognitive processes among patients lost to follow-up for HIV care and develop interventions to improve their engagement...
2016: Open AIDS Journal
Engetani Nkuna, Norman Z Nyazema
HIV self-testing (HIVST) is an empowering process in which an individual performs an HIV rapid diagnostic test and interprets the result in privacy. Policy makers have turned to it to facilitate greater uptake, earlier diagnosis, access to prevention, care and treatment services. The University of Limpopo now has an established HIV counselling and testing (HCT) service. Unfortunately, the uptake of this HCT service by the student body is not encouraging. It was against this background that a study was carried out among health sciences students, to assess the potential of HIVST to increase access to and uptake of HIV testing on campus...
2016: Open AIDS Journal
Nana K Poku
There is no viable substitute for re-energizing, funding and supporting culturally attuned, locally staffed HIV advocacy and prevention programmes, especially in resource poor settings. The evidence that such interventions are effective remains compelling; and although the cost implications are not negligible, the medium to long-term outcomes must be regarded not as complementary, but as integral, to biomedical interventions. The success of the anti-retroviral drugs upscale has enabled a noticeable improvement in AIDS related morbidity and mortality in the recent years; yet the underlying dynamics of the epidemic remains undetermined by the rate at which new infections are taking place in relation to the number of AIDS deaths...
2016: Open AIDS Journal
Meredith G B Evans, Allanise Cloete, Nompumelelo Zungu, Leickness C Simbayi
BACKGROUND: The HIV epidemic in South Africa is characterized mainly by heterosexual transmission. Recently, the importance of targeting key populations and marginalized groups, including men who have sex with men (MSM) and transgender people, has been added to the national agenda. OBJECTIVES: This mini-review explores the current state of empirical research on HIV risk and MSM, women who have sex with women (WSW), lesbian, gay, bisexual and transgender (LGBT) populations in South Africa in order to assess the current state of research and identify gaps in the literature...
2016: Open AIDS Journal
Ayesha B M Kharsany, Quarraisha A Karim
Global trends in HIV infection demonstrate an overall increase in HIV prevalence and substantial declines in AIDS related deaths largely attributable to the survival benefits of antiretroviral treatment. Sub-Saharan Africa carries a disproportionate burden of HIV, accounting for more than 70% of the global burden of infection. Success in HIV prevention in sub-Saharan Africa has the potential to impact on the global burden of HIV. Notwithstanding substantial progress in scaling up antiretroviral therapy (ART), sub-Saharan Africa accounted for 74% of the 1...
2016: Open AIDS Journal
Nawa Sanjobo, Matilda Lukwesa, Charity Kaziya, Cornwell Tepa, Bernard Puta
BACKGROUND: Universities present the foundation for socio-economic and political development. Without structures and processes to fight HIV, there is no prospect of enhancing treatment, prevention, care and support services. Copperbelt University HIV and AIDS response was initiated in 2003 with the aim of building capacity of students and employees in HIV and AIDS. OBJECTIVES: The main objective of this paper is to demonstrate how the CBU HIV response has evolved over time and provide a timeline of important milestones in the development process...
2016: Open AIDS Journal
K Bowa, B Kawimbe, D Mugala, D Musowoya, A Makupe, M Njobvu, C Simutowe
HIV has a significant impact on surgery in Africa. Its' influence has spanned a period of about 30 years. In the 1980s' Africa experienced a rise in the national prevalence of HIV spreading across East Africa through Southern Africa, and reaching peak prevalence in the Southern African region. These prevalence levels have affected four key areas of surgical practice; namely patient care, practice of surgery, surgical pathologies, the practitioner and more recently prevention. The surgical patient is more likely to be HIV positive in Africa, than elsewhere in the world...
2016: Open AIDS Journal
Oscar O Simooya
No abstract text is available yet for this article.
2016: Open AIDS Journal
Kristin M Wall, Lauren Canary, Kimberly Workowski, Annie Lockard, Jeb Jones, Patrick Sullivan, Katherine Hills, Kadija Fofana, Rob Stephenson, Susan Allen
INTRODUCTION: Couples' voluntary HIV counseling and testing (CHTC) is an HIV risk reduction strategy not widely available in the US. METHODS: We assessed willingness to participate in CHTC among US HIV-infected clinic patients via tablet-based survey and among HIV-negative persons with HIV-infected partners in care via mixed-method phone interviews. RESULTS: Most of the N=64 HIV-infected partners surveyed were men (89%), on antiretroviral treatment (ART) (92%), and many self-identified homosexual (62%)...
2016: Open AIDS Journal
Kate Buchacz, Emma L Frazier, H Irene Hall, Rachel Hart, Ping Huang, Dana Franklin, Xiaohong Hu, Frank J Palella, Joan S Chmiel, Richard M Novak, Kathy Wood, Bienvenido Yangco, Carl Armon, John T Brooks, Jacek Skarbinski
Comparative analyses of the characteristics of persons living with HIV infection (PLWH) in the United States (US) captured in surveillance and other observational databases are few. To explore potential joint data use to guide HIV treatment and prevention in the US, we examined three CDC-funded data sources in 2012: the HIV Outpatient Study (HOPS), a multisite longitudinal cohort; the Medical Monitoring Project (MMP), a probability sample of PLWH receiving medical care; and the National HIV Surveillance System (NHSS), a surveillance system of all PLWH...
2015: Open AIDS Journal
Marian P Laderoute, Louise J Larocque, Antonio Giulivi, Francisco Diaz-Mitoma
OBJECTIVE: The goals of the research were to determine if a foamy effect on macrophages was due to human endogenous retrovirus K102 (HERV-K102) replication, and to further address its potential significance in HIV-1 infection. METHODS: An RT-PCR HERV-K HML-2 pol method was used to screen the unknown HERV, and isolated bands were sent for sequencing. Confirmation of RNA expression was performed by a real time quantitative PCR (qPCR) pol ddCt method. Rabbit antibodies to Env peptides were used to assess expression by immunohistology and processing of Env by western blots...
2015: Open AIDS Journal
Wamalwa Emmanuel, Neyole Edward, Poipoi Moses, Ringera William, Otomu Geoffrey, Bitok Monicah, Mbaluka Rosemary
The male condom remains the single, most efficient and available technology to reduce sexual transmission of HIV as well as sexually transmitted infections. This study sought to establish condom use determinants and practices among people living with HIV (PLHIVs) in Kisii County, Kenya. We interviewed 340 PLHIVs and 6 health workers. Although most PLHIVs had correct knowledge and approved condoms as effective for HIV prevention, consistent use and condom use at last sex were notably low especially among PLHIVs aged 18 - 24, those who depended on remittances from kin as main source of income, as well as during sex with secondary and casual partners...
2015: Open AIDS Journal
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