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Open Virology Journal

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https://www.readbyqxmd.com/read/30288201/impact-of-emerging-re-emerging-and-zoonotic-viral-infectious-diseases-in-a-virologist-s-perspective
#1
Nobumichi Kobayashi
No abstract text is available yet for this article.
2018: Open Virology Journal
https://www.readbyqxmd.com/read/30288200/japanese-encephalitis-a-brief-review-on-indian-perspectives
#2
REVIEW
Reshma Kulkarni, Gajanan N Sapkal, Himanshu Kaushal, Devendra T Mourya
Introduction: Japanese encephalitis (JE) is recently declared as a notifiable disease in India due to its expanding geographical distribution. The disease notification facilitates effective implementation of preventive measures and case management. Expalantion: JE is a vector-borne disease that can be prevented by vaccine administration. It is caused by Japanese encephalitis virus (JEV), belonging to family Flaviviridae . Amongst the known etiological viral encephalitis agents, it is one of the leading viral agents of acute encephalitis syndrome in many Asian countries where it is identified to cause substantial morbidity and mortality as well as disability...
2018: Open Virology Journal
https://www.readbyqxmd.com/read/30288199/evidence-of-bvdv-in-pigs-from-north-eastern-part-of-india-genetic-profiling-and-characterisation
#3
Amit Kr Chakraborty, Priyanka Mukherjee, Amarjit Karam, Samir Das, Luit Barkalita, Kekungo Puro, Rajkumari Sanjukta, Sandeep Ghatak, Ingudam Sakuntala, Ram Gopal Laha, Prabodh Borah, S V Ngachan, Indu Sharma, Arnab Sen
Introduction: The work has been attempted to detect and genetically characterise the nature of Bovine Viral Diarrhea Virus (BVDV) isolates from the porcine population of the north east. Methods and Material: The samples have been collected over a two year period and are from areas where there is a mixed and integrated rearing of livestock in close proximity. The isolates were identified, cloned and sequenced using BVD specific genomic primers for two important domains viz...
2018: Open Virology Journal
https://www.readbyqxmd.com/read/30288198/epidemiologic-status-of-picobirnavirus-in-india-a-less-explored-viral-disease
#4
REVIEW
Yashpal Singh Malik, Shubhankar Sircar, Sharad Saurabh, Jobin Jose Kattoor, Rashmi Singh, Balasubramanian Ganesh, Souvik Ghosh, Kuldeep Dhama, Raj Kumar Singh
Since the unexpected discovery of picobirnaviruses (PBV) in 1988, they have been reported in many animals including mammals and birds, which comprises both terrestrial and marine species. Due to their divergent characteristics to other viral taxa they are classified into a new family Picobirnaviridae . Although their pathogenicity and role in causing diarrhea still remains a question since they have been discovered in symptomatic and asymptomatic cases both. Recent studies employing state-of-art molecular tools have described their presence in various clinical samples, like stool samples from different mammals and birds, respiratory tracts of pigs and humans, sewage water, different foods, etc ...
2018: Open Virology Journal
https://www.readbyqxmd.com/read/30288197/zoonotic-viral-diseases-of-equines-and-their-impact-on-human-and-animal-health
#5
REVIEW
Balvinder Kumar, Anju Manuja, B R Gulati, Nitin Virmani, B N Tripathi
Introduction: Zoonotic diseases are the infectious diseases that can be transmitted to human beings and vice versa from animals either directly or indirectly. These diseases can be caused by a range of organisms including bacteria, parasites, viruses and fungi. Viral diseases are highly infectious and capable of causing pandemics as evidenced by outbreaks of diseases like Ebola, Middle East Respiratory Syndrome, West Nile, SARS-Corona, Nipah, Hendra, Avian influenza and Swine influenza...
2018: Open Virology Journal
https://www.readbyqxmd.com/read/30288196/the-quest-for-materials-based-hydrogels-with-antimicrobial-and-antiviral-potentialities
#6
REVIEW
Hafiz M N Iqbal
In recent years, the Antimicrobial Resistance (AMR) or Multidrug Resistance (MDR) and viral infections have become serious health issues, globally. Finally, after decades of negligence, the AMR/MDR and viral infection issues have now captured a worldwide attention of the global leaders, public health community, legalization authorities, academia, research-based organizations, and medicinal sector of the modern world, alike. Aiming to resolve these issues, various methodological approaches have been exploited, in the past several years...
2018: Open Virology Journal
https://www.readbyqxmd.com/read/30288195/adaptation-of-newcastle-disease-virus-ndv-in-feral-birds-and-their-potential-role-in-interspecies-transmission
#7
REVIEW
Aziz-Ul- Rahman, Momena Habib, Muhammad Zubair Shabbir
Introduction: Newcastle Disease (ND), caused by Avian avulavirus 1 (AAvV 1, avulaviruses), is a notifiable disease throughout the world due to the economic impact on trading restrictions and its embargoes placed in endemic regions. The feral birds including aquatic/migratory birds and other wild birds may act as natural reservoir hosts of ND Viruses (NDVs) and may play a remarkable role in the spread of the virus in environment. In addition, other 19 avulaviruses namely: AAvV 2 to 20, have been potentially recognized from feral avian species...
2018: Open Virology Journal
https://www.readbyqxmd.com/read/30288194/chandipura-viral-encephalitis-a-brief-review
#8
REVIEW
Gajanan N Sapkal, Pradeep M Sawant, Devendra T Mourya
Introduction: In recent years, the Chandipura virus (CHPV) has emerged as an encephalitic pathogen and found associated with a number of outbreaks in different parts of India. Children under 15 years of age are most susceptible to natural infection. CHPV is emerging as a significant encephalitis, causing virus in the Indian subcontinent. Severe outbreaks caused by the virus have been reported from several parts of India. Expalanation: In the recent past, the noticeable association of CHPV with pediatric sporadic encephalitis cases as well as a number of outbreaks in Andhra Pradesh (2004, 2005, 2007 and 2008), Gujarat in (2005, 2009-12) and Vidarbha region of Maharashtra (2007, 2009-12) have been documented...
2018: Open Virology Journal
https://www.readbyqxmd.com/read/30288193/emerging-and-zoonotic-virus-challenges-of-developing-nations
#9
EDITORIAL
Yashpal Singh Malik, Kuldeep Dhama, Raj Kumar Singh
No abstract text is available yet for this article.
2018: Open Virology Journal
https://www.readbyqxmd.com/read/29576813/determining-the-actual-prevalence-of-hepatitis-b-in-khyber-pakhtunkhwa-pakistan-a-meta-analysis
#10
Najeeb Ullah Khan, Ali Zalan, Arnolfo Petruzziello, Iftikhar Ud Din, Fazle Haq, Yousaf Hayat
Background: Hepatitis B is considered the most dangerous among the five types of Hepatitis, as it is clinically asymptomatic. It can silently damage the liver over many years without being diagnosed. Hepatitis B is one of the top risks of liver complications in Khyber Pakhtunkhwa (KP), a province of Pakistan, with an average prevalence rate of 2.70%. Aims: We aimed to carefully review the previously published data on prevalence of Hepatitis B Virus (HBV) in KP-Pakistan and use the statistical approach to obtain more precise estimate of the prevalence of HBV in KP-Pakistan...
2018: Open Virology Journal
https://www.readbyqxmd.com/read/29541276/epidemiology-of-hepatitis-b-virus-hbv-and-hepatitis-c-virus-hcv-related-hepatocellular-carcinoma
#11
REVIEW
Arnolfo Petruzziello
Introduction: Hepatocellular carcinoma (HCC) is one of the most prevalent primary malignant tumors and accounts for about 90% of all primary liver cancers. Its distribution varies greatly according to geographic location and it is more common in middle and low- income countries than in developed ones especially in Eastern Asia and Sub Saharan Africa (70% of all new HCCs worldwide), with incidence rates of over 20 per 100,000 individuals. Explanation: The most important risk factors for HCC are Hepatitis B Virus (HBV) infection, Hepatitis C Virus (HCV) infection, excessive consumption of alcohol and exposition to aflatoxin B1...
2018: Open Virology Journal
https://www.readbyqxmd.com/read/29541275/hepatitis-c-virus-and-hepatocellular-carcinoma-pathogenetic-mechanisms-and-impact-of-direct-acting-antivirals
#12
REVIEW
Ivan Schietroma, Giuseppe Corano Scheri, Claudia Pinacchio, Maura Statzu, Arnolfo Petruzziello, Vincenzo Vullo
Introduction: Globally, between 64 and 103 million people are chronically infected with Hepatitis C virus (HCV), with more than 4.6 million people in the United States and is associated with more than 15.000 deaths annually. Chronic infection can result in cirrhosis and hepatocellular carcinoma. Explanation: Epidemiological studies have indicated that persistent infection with hepatitis C virus (HCV) is a major risk for the development of hepatocellular carcinoma (HCC), mainly through chronic inflammation, cell deaths, and proliferation...
2018: Open Virology Journal
https://www.readbyqxmd.com/read/29541274/viral-replication-and-progression-of-cancer
#13
EDITORIAL
Guest Editor S, Arnolfo Petruzziello
No abstract text is available yet for this article.
2018: Open Virology Journal
https://www.readbyqxmd.com/read/29541273/protection-efficacy-of-c5a-against-vaginal-and-rectal-hiv-challenges-in-humanized-mice
#14
Philippe A Gallay, Udayan Chatterji, Aaron Kirchhoff, Angel Gandarilla, Richard B Pyles, Marc M Baum, John A Moss
Introduction: In the absence of a vaccine, there is an urgent need for the identification of effective agents that prevent HIV transmission in uninfected individuals. Non-vaccine Biomedical Prevention (nBP) methods, such as topical or systemic pre-exposure prophylaxis (PrEP), are promising strategies to slow down the spread of AIDS. Methods: In this study, we investigated the microbicidal efficacy of the viral membrane-disrupting amphipathic SWLRDIWDWICEVLSDFK peptide called C5A...
2018: Open Virology Journal
https://www.readbyqxmd.com/read/29399232/a-diagnostic-laboratory-based-study-on-frequency-and-distribution-of-viral-hepatitis-b-and-c-among-sudanese
#15
Marwan M Badawi, Alshaimaa A Mohammed, Mohammed S Mohammed, Mohammed M Saeed, Elmoez Y Ali, Ashraf Khalil
Background: Hepatitis B infection is an alarming public health problem. Almost two billion people of the population alive today, would have been infected at some time in their lives by hepatitis B. Hepatitis C virus is another life threatening condition, and about 425,000 deaths occur each year due to its complications.The current study was carried out to provide care givers and health planners basic epidemiological data regarding the frequency and distribution of HBV and HCV based on age and sex during a time period of more than 5 years...
2017: Open Virology Journal
https://www.readbyqxmd.com/read/28839509/analysis-of-genetic-variation-of-two-nadc30-like-strains-of-porcine-reproductive-and-respiratory-syndrome-virus-in-china
#16
Zhi Zhou, Jiajun Wu, Shuo Zhang, Bo Hou, Tao Han, Jing Wang, Qi Xu, Dongyue Wang, Yinyi Liu, Shengpeng Xin, Xinyan Zhai
BACKGROUND: NADC30-like strains of porcine reproductive and respiratory syndrome virus first appeared in Chinese swine herds in 2012. OBJECTIVE AND METHOD: To explore the possible genetic diversity of these strains, we sequenced and analyzed the complete genomes of two NADC30-like strains. These isolates shared 95.4% homology with NADC30. RESULT: The two strains displayed a discontinuous deletion of 131 amino acids in NSP2, mutations of amino acids in GP3 and GP5, and a 3-nucleotide deletion in the 3' untranslated region...
2017: Open Virology Journal
https://www.readbyqxmd.com/read/28839508/pathogenic-characterization-of-european-genotype-porcine-reproductive-and-respiratory-syndrome-virus-recently-isolated-in-mainland-china
#17
Sun Ming, Ma Yongying, Liu Bohua, Lu Huiying, Deng Xiaoyu, Liu Qiaorong, Qiao Mingming, Chen Xi, Yang Xinyan, Chen Xizhao
BACKGROUND: Porcine reproductive and respiratory syndrome virus (PRRSV) is an important pathogen in pig that causes tremendous economic loss in the global swine industry. PRRSV is divided into the European and North American genotypes, with virulence ranging from apathogenic-moderately virulent to highly pathogenic. The emergence of new highly virulent type 1 strains and coexistence of the two genotypes complicate the differential diagnosis, disease prevention, and control of PRRSV. Although the emergence of a novel type 1 PRRSV strain in mainland China was first confirmed in 2011, there is no information available concerning the pathogenesis of this strain...
2017: Open Virology Journal
https://www.readbyqxmd.com/read/28839507/comparison-of-immune-responses-in-pigs-infected-with-chinese-highly-pathogenic-prrs-virus-strain-hv-and-north-american-strain-nadc-20
#18
X Li, A Galliher-Beckley, L Wang, J Nietfeld, W Feng, J Shi
INTRODUCTION: Chinese HP-PRRSV characterized by high morbidity and mortality of all ages of pigs emerged since 2006 in China. The immune response of HP-PRRSV was never compared with conventional low pathogenic PRRSV strain. OBJECTIVE: In this study, we compared the immune responses elicited by a Chinese HP-PRRSV strain HV and a North American RRSV strain NADC20 infections. RESULT: Pigs infected with NADC-20 showed significantly higher Ab titers than HV-PRRSV infected pigs at 9 DPI...
2017: Open Virology Journal
https://www.readbyqxmd.com/read/28839506/development-and-application-of-an-rt-pcr-to-differentiate-the-prevalent-na-prrsv-strains-in-china
#19
Yanlin Li, Guobiao Ji, Xiaodong Xu, Juan Wang, Yingying Li, Feifei Tan, Xiangdong Li
BACKGROUND: PRRSV features with genetic diversity and high mutation which leads to the emergence of a multiple of circulating virus strains with different virulence. North American (genotype 2) PRRSV (NA-PRRSV) can be divided into classical PRRSV (C-PRRSV), highly pathogenic PRRSV (HP-PRRSV), and NADC30-like PRRSV (NL-PRRSV) according to their genomic characteristics and pathogenicity. So far, the above three subtypes of NA-PRRSV are now circulating in China. OBJECTIVE AND METHOD: In this study, a reverse transcript polymerase chain reaction (RT-PCR) was established to simultaneously differentiate three subtypes of NA-PRRSV...
2017: Open Virology Journal
https://www.readbyqxmd.com/read/28839505/nadc30-like-porcine-reproductive-and-respiratory-syndrome-in-china
#20
REVIEW
Kegong Tian
NADC30-like porcine reproductive and respiratory syndrome virus (PRRSV) has widely spread in China and become locally dominant virus strain in some provinces. Although they are not pathogenic as highly pathogenic PRRSV (HP-RRRSV) that outbreaks since 2006, NADC30-like PRRSVs distinguished themselves by high incidence of recombination with other virus strains which lead to change of virulence. The outbreaks of NADC30-like PRRSV in the vaccinated pig herds suggested that current commercial PRRSV vaccines cannot provide complete protection to the infection...
2017: Open Virology Journal
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